id author title date pages extension mime words sentences flesch summary cache txt cord-351964-hduv0ur4 nan Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells 1987-09-01 .txt text/plain 7606 355 54 The virus, which buds into pre-Golgi compartments, moves through the Golgi cisternae and exploits vesicles of the constitutive exocytic pathway of these fibroblastic hosts, which lack a regulated pathway, to reach the cell surface; the post-Golgi vesicles filled with progeny virions that can be seen near the cell surface apparently fuse with the plasma membrane to release the virus into the medium (for review see Dubois-Dalcq et al., 1984) . Condensation of secretory proteins and the formation of secretory granules of the regulated exocytic pathway occurs exclusively in the trans-Golgi network in uninfected AtT20 cells . B shows, near the lower surface of a cell growing on ECM, one of the extremely rare classes of post-Golgi transport vesicles which contain both virions (arrows) and a clump of condensed secretory protein that labels heavily with anti-ACTH antibody (arrowhead). In AtT20 cells, at 7-10-h postinfection with MHV-A59, both progeny virions and condensing secretory proteins accumulate in the trans-Golgi network. ./cache/cord-351964-hduv0ur4.txt ./txt/cord-351964-hduv0ur4.txt