id author title date pages extension mime words sentences flesch summary cache txt cord-326015-ky4y2xjt Füllekrug, Joachim Protein sorting in the Golgi complex 1998-08-14 .txt text/plain 3937 202 50 In this review, we will discuss sorting of resident proteins in the Golgi complex mainly in the context of cisternal maturation [1, 2] . An essential feature of this maturation model is the prediction that Golgi resident proteins are more concentrated in retrograde vesicles than they are in the cisternae of the Golgi apparatus. This shows that Golgi resident enzymes do form gradients across the pathway and that these are unique to the particular protein. The surprising ¢nding that the membrane spanning domain (MSD) of Golgi residents su¤ced to localise reporter molecules to the appropriate part of the pathway suggested that this domain harboured important sorting information (for review, see [22] ). As this form of coatomer is found on Golgi associated transport vesicles [50] , COP I vesicles constitute RTCs. The presence of K(X)KXX or related signals on membrane proteins other than ER residents allows for the possibility that this motif also acts later in the pathway. ./cache/cord-326015-ky4y2xjt.txt ./txt/cord-326015-ky4y2xjt.txt