id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-271501-yjobthaj	Hirschberg, Carlos B.	Transporters of nucleotide sugars, nucleotide sulfate and ATP in the Golgi apparatus membrane: Where next?	1997-02-17		.txt	text/plain	1961	96	39	UMP is the antiporter for all undine containing nucleotide sugars (Hirschberg and Snider, 1987; Waldman and Rudnick, 1990; Milla et al., 1992) ; thus, one would expect all these uridine nucleotide sugar transporters to have common structural features facing the lumenal and cytosolic side of the membrane. Recent evidence in mammals and yeast suggests that Golgi membrane transporters play a regulatory role in determining which macromolecules undergo specific posttranslational modifications in the lumen of the Golgi apparatus (Abeijon et al., 1993; Toma et al., 1996) . A combination of genetics and overexpression of wild-type and mutant transporter proteins followed by reconstitution into liposomes should allow determination of structural motifs required for membrane insertion, nucleotide recognition, and specific sugar translocation. What structural features determine that these transporters become localized in the Golgi apparatus and/or the endoplasmic reticulum and not another organelle?	./cache/cord-271501-yjobthaj.txt	./txt/cord-271501-yjobthaj.txt