id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-104269-9r7rqqqk	nan	Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment	1994-07-02		.txt	text/plain	8622	384	48	title: Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment Ii-TR chimera containing the Ii cytoplasmic tail and transmembrane region is delivered directly to the endocytic pathway by an intracellular route, implying that the Ii sorting signals are efficiently recognized by sorting machinery located in the trans-Golgi. Ii-TR chimera containing the Ii cytoplasmic tail and transmembrane region is delivered directly to the endocytic pathway by an intracellular route, implying that the Ii sorting signals are efficiently recognized by sorting machinery located in the trans-Golgi. Further, the rate of synthesis of the Iicx and Iicr+m chimeras was 4-and 8-fold higher, respectively, than that of wild-type TR even though the chimeric receptors were expressed in lower amounts on the cell surface suggesting most of the chimeric molecules were trafficking by a direct intracellular route to the endocytic compartment where they were degraded.	./cache/cord-104269-9r7rqqqk.txt	./txt/cord-104269-9r7rqqqk.txt