id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-004521-25t4s7fr	Marie, M.	Membrane traffic in the secretory pathway: Take the ’A’ train: on fast tracks to the cell surface	2008-08-26		.txt	text/plain	9278	431	46	Typical for this transport is (i) its insensitivity to brefeldin A (BFA), which dissociates selected coat complexes from membranes, resulting in the disassembly of the Golgi apparatus; (ii) its rapid kinetics as compared to the classical secretory pathway; and (iii) its role in the trafficking of lipid raft components. COPII coats function at ER exit sites in the initial export of cargo from the ER [22, 23] , COPI coats operate in forward transport and recycling in the IC and cis-Golgi membranes [24] , while clathrin and associated adaptor proteins (AP1, AP3, AP4, GGA) localize variably to trans-Golgi/TGN and endosomes [25] . However, since different cargo proteins display variable localization in the 20 o C-treated cells, it remained unclear whether they are arrested in a specialized trans-Golgi secretory organelle, or within a complex membrane system located at the crossroads of the exocytic and endocytic pathways [127, 130, 9a] .	./cache/cord-004521-25t4s7fr.txt	./txt/cord-004521-25t4s7fr.txt