id author title date pages extension mime words sentences flesch summary cache txt cord-001082-sufwsu77 Bär, Séverine Vesicular Transport of Progeny Parvovirus Particles through ER and Golgi Regulates Maturation and Cytolysis 2013-09-19 .txt text/plain 8949 468 46 By colocalization with cellular marker proteins and specific modulation of the pathways through over-expression of variant effector genes transduced by recombinant adeno-associated virus vectors, we show that progeny PV particles become engulfed into COPII-vesicles in the endoplasmic reticulum (ER) and are transported through the Golgi to the plasma membrane. Moreover, a very limited reduction of secreted particles was observed with dnRab11, and nothing at all upon inhibition of Rab8, suggesting that PV particles take a different route from the Golgi apparatus to the plasma membrane as compared to GLuc. Due to their impact on MVM plaque morphology in A9 cells, the ERM family proteins moesin (Moe) and radixin (Rdx) have been implicated in the spreading capacity of this parvovirus [38] . ./cache/cord-001082-sufwsu77.txt ./txt/cord-001082-sufwsu77.txt