id	sid	tid	token	lemma	pos
cord-350019-4nlbu54e	1	1	key	key	NN
cord-350019-4nlbu54e	1	2	:	:	:
cord-350019-4nlbu54e	2	1	cord-350019	cord-350019	NNP
cord-350019-4nlbu54e	2	2	-	-	HYPH
cord-350019-4nlbu54e	2	3	4nlbu54e	4nlbu54e	CD
cord-350019-4nlbu54e	2	4	authors	author	NNS
cord-350019-4nlbu54e	2	5	:	:	:
cord-350019-4nlbu54e	2	6	Robinson	Robinson	NNP
cord-350019-4nlbu54e	2	7	,	,	,
cord-350019-4nlbu54e	2	8	Elektra	Elektra	NNP
cord-350019-4nlbu54e	2	9	K.	K.	NNP
cord-350019-4nlbu54e	2	10	;	;	:
cord-350019-4nlbu54e	2	11	Covarrubias	Covarrubias	NNP
cord-350019-4nlbu54e	2	12	,	,	,
cord-350019-4nlbu54e	2	13	Sergio	Sergio	NNP
cord-350019-4nlbu54e	2	14	;	;	:
cord-350019-4nlbu54e	2	15	Carpenter	Carpenter	NNP
cord-350019-4nlbu54e	2	16	,	,	,
cord-350019-4nlbu54e	3	1	Susan	Susan	NNP
cord-350019-4nlbu54e	3	2	title	title	NN
cord-350019-4nlbu54e	3	3	:	:	:
cord-350019-4nlbu54e	4	1	The	the	DT
cord-350019-4nlbu54e	4	2	how	how	WRB
cord-350019-4nlbu54e	4	3	and	and	CC
cord-350019-4nlbu54e	4	4	why	why	WRB
cord-350019-4nlbu54e	4	5	of	of	IN
cord-350019-4nlbu54e	4	6	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	4	7	function	function	NN
cord-350019-4nlbu54e	4	8	:	:	:
cord-350019-4nlbu54e	4	9	An	an	DT
cord-350019-4nlbu54e	4	10	innate	innate	JJ
cord-350019-4nlbu54e	4	11	immune	immune	JJ
cord-350019-4nlbu54e	4	12	perspective	perspective	NN
cord-350019-4nlbu54e	4	13	(	(	-LRB-
cord-350019-4nlbu54e	4	14	)	)	-RRB-
cord-350019-4nlbu54e	4	15	date	date	NN
cord-350019-4nlbu54e	4	16	:	:	:
cord-350019-4nlbu54e	4	17	2019	2019	CD
cord-350019-4nlbu54e	4	18	-	-	HYPH
cord-350019-4nlbu54e	4	19	09	09	CD
cord-350019-4nlbu54e	4	20	-	-	HYPH
cord-350019-4nlbu54e	4	21	02	02	CD
cord-350019-4nlbu54e	4	22	journal	journal	NN
cord-350019-4nlbu54e	4	23	:	:	:
cord-350019-4nlbu54e	5	1	Biochim	Biochim	NNP
cord-350019-4nlbu54e	5	2	Biophys	Biophys	NNP
cord-350019-4nlbu54e	6	1	Acta	Acta	NNP
cord-350019-4nlbu54e	6	2	Gene	Gene	NNP
cord-350019-4nlbu54e	7	1	Regul	Regul	NNP
cord-350019-4nlbu54e	7	2	Mech	Mech	NNP
cord-350019-4nlbu54e	7	3	DOI	DOI	NNP
cord-350019-4nlbu54e	7	4	:	:	:
cord-350019-4nlbu54e	8	1	10.1016/	10.1016/	CD
cord-350019-4nlbu54e	9	1	j.bbagrm.2019.194419	j.bbagrm.2019.194419	NNP
cord-350019-4nlbu54e	9	2	sha	sha	NNP
cord-350019-4nlbu54e	9	3	:	:	:
cord-350019-4nlbu54e	9	4	a849cf92949f2e1ac39d231b788cd410bf211487	a849cf92949f2e1ac39d231b788cd410bf211487	NNP
cord-350019-4nlbu54e	9	5	doc_id	doc_id	CD
cord-350019-4nlbu54e	9	6	:	:	:
cord-350019-4nlbu54e	9	7	350019	350019	CD
cord-350019-4nlbu54e	9	8	cord_uid	cord_uid	NNS
cord-350019-4nlbu54e	9	9	:	:	:
cord-350019-4nlbu54e	10	1	4nlbu54e	4nlbu54e	LS
cord-350019-4nlbu54e	10	2	Next	next	JJ
cord-350019-4nlbu54e	10	3	-	-	HYPH
cord-350019-4nlbu54e	10	4	generation	generation	NN
cord-350019-4nlbu54e	10	5	sequencing	sequencing	NN
cord-350019-4nlbu54e	10	6	has	have	VBZ
cord-350019-4nlbu54e	10	7	provided	provide	VBN
cord-350019-4nlbu54e	10	8	a	a	DT
cord-350019-4nlbu54e	10	9	more	more	RBR
cord-350019-4nlbu54e	10	10	complete	complete	JJ
cord-350019-4nlbu54e	10	11	picture	picture	NN
cord-350019-4nlbu54e	10	12	of	of	IN
cord-350019-4nlbu54e	10	13	the	the	DT
cord-350019-4nlbu54e	10	14	composition	composition	NN
cord-350019-4nlbu54e	10	15	of	of	IN
cord-350019-4nlbu54e	10	16	the	the	DT
cord-350019-4nlbu54e	10	17	human	human	JJ
cord-350019-4nlbu54e	10	18	transcriptome	transcriptome	NN
cord-350019-4nlbu54e	10	19	indicating	indicate	VBG
cord-350019-4nlbu54e	10	20	that	that	IN
cord-350019-4nlbu54e	10	21	much	much	JJ
cord-350019-4nlbu54e	10	22	of	of	IN
cord-350019-4nlbu54e	10	23	the	the	DT
cord-350019-4nlbu54e	10	24	“	"	``
cord-350019-4nlbu54e	10	25	blueprint	blueprint	NN
cord-350019-4nlbu54e	10	26	”	"	''
cord-350019-4nlbu54e	10	27	is	be	VBZ
cord-350019-4nlbu54e	10	28	a	a	DT
cord-350019-4nlbu54e	10	29	vastness	vastness	NN
cord-350019-4nlbu54e	10	30	of	of	IN
cord-350019-4nlbu54e	10	31	poorly	poorly	RB
cord-350019-4nlbu54e	10	32	understood	understand	VBN
cord-350019-4nlbu54e	10	33	non	non	JJ
cord-350019-4nlbu54e	10	34	-	-	JJ
cord-350019-4nlbu54e	10	35	protein	protein	JJ
cord-350019-4nlbu54e	10	36	-	-	HYPH
cord-350019-4nlbu54e	10	37	coding	code	VBG
cord-350019-4nlbu54e	10	38	transcripts	transcript	NNS
cord-350019-4nlbu54e	10	39	.	.	.
cord-350019-4nlbu54e	11	1	This	this	DT
cord-350019-4nlbu54e	11	2	includes	include	VBZ
cord-350019-4nlbu54e	11	3	a	a	DT
cord-350019-4nlbu54e	11	4	newly	newly	RB
cord-350019-4nlbu54e	11	5	identified	identify	VBN
cord-350019-4nlbu54e	11	6	class	class	NN
cord-350019-4nlbu54e	11	7	of	of	IN
cord-350019-4nlbu54e	11	8	genes	gene	NNS
cord-350019-4nlbu54e	11	9	called	call	VBN
cord-350019-4nlbu54e	11	10	long	long	JJ
cord-350019-4nlbu54e	11	11	noncoding	noncoding	JJ
cord-350019-4nlbu54e	11	12	RNAs	rna	NNS
cord-350019-4nlbu54e	11	13	(	(	-LRB-
cord-350019-4nlbu54e	11	14	lncRNAs	lncrnas	RB
cord-350019-4nlbu54e	11	15	)	)	-RRB-
cord-350019-4nlbu54e	11	16	.	.	.
cord-350019-4nlbu54e	12	1	The	the	DT
cord-350019-4nlbu54e	12	2	lack	lack	NN
cord-350019-4nlbu54e	12	3	of	of	IN
cord-350019-4nlbu54e	12	4	sequence	sequence	NN
cord-350019-4nlbu54e	12	5	conservation	conservation	NN
cord-350019-4nlbu54e	12	6	for	for	IN
cord-350019-4nlbu54e	12	7	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	12	8	across	across	IN
cord-350019-4nlbu54e	12	9	species	specie	NNS
cord-350019-4nlbu54e	12	10	meant	mean	VBN
cord-350019-4nlbu54e	12	11	that	that	IN
cord-350019-4nlbu54e	12	12	their	-PRON-	PRP$
cord-350019-4nlbu54e	12	13	biological	biological	JJ
cord-350019-4nlbu54e	12	14	importance	importance	NN
cord-350019-4nlbu54e	12	15	was	be	VBD
cord-350019-4nlbu54e	12	16	initially	initially	RB
cord-350019-4nlbu54e	12	17	met	meet	VBN
cord-350019-4nlbu54e	12	18	with	with	IN
cord-350019-4nlbu54e	12	19	some	some	DT
cord-350019-4nlbu54e	12	20	skepticism	skepticism	NN
cord-350019-4nlbu54e	12	21	.	.	.
cord-350019-4nlbu54e	13	1	LncRNAs	LncRNAs	NNP
cord-350019-4nlbu54e	13	2	mediate	mediate	VBP
cord-350019-4nlbu54e	13	3	their	-PRON-	PRP$
cord-350019-4nlbu54e	13	4	functions	function	NNS
cord-350019-4nlbu54e	13	5	through	through	IN
cord-350019-4nlbu54e	13	6	interactions	interaction	NNS
cord-350019-4nlbu54e	13	7	with	with	IN
cord-350019-4nlbu54e	13	8	proteins	protein	NNS
cord-350019-4nlbu54e	13	9	,	,	,
cord-350019-4nlbu54e	13	10	RNA	RNA	NNP
cord-350019-4nlbu54e	13	11	,	,	,
cord-350019-4nlbu54e	13	12	DNA	DNA	NNP
cord-350019-4nlbu54e	13	13	,	,	,
cord-350019-4nlbu54e	13	14	or	or	CC
cord-350019-4nlbu54e	13	15	a	a	DT
cord-350019-4nlbu54e	13	16	combination	combination	NN
cord-350019-4nlbu54e	13	17	of	of	IN
cord-350019-4nlbu54e	13	18	these	these	DT
cord-350019-4nlbu54e	13	19	.	.	.
cord-350019-4nlbu54e	14	1	Their	-PRON-	PRP$
cord-350019-4nlbu54e	14	2	functions	function	NNS
cord-350019-4nlbu54e	14	3	can	can	MD
cord-350019-4nlbu54e	14	4	often	often	RB
cord-350019-4nlbu54e	14	5	be	be	VB
cord-350019-4nlbu54e	14	6	dictated	dictate	VBN
cord-350019-4nlbu54e	14	7	by	by	IN
cord-350019-4nlbu54e	14	8	their	-PRON-	PRP$
cord-350019-4nlbu54e	14	9	localization	localization	NN
cord-350019-4nlbu54e	14	10	,	,	,
cord-350019-4nlbu54e	14	11	sequence	sequence	NN
cord-350019-4nlbu54e	14	12	,	,	,
cord-350019-4nlbu54e	14	13	and/or	and/or	CC
cord-350019-4nlbu54e	14	14	secondary	secondary	JJ
cord-350019-4nlbu54e	14	15	structure	structure	NN
cord-350019-4nlbu54e	14	16	.	.	.
cord-350019-4nlbu54e	15	1	Here	here	RB
cord-350019-4nlbu54e	15	2	we	-PRON-	PRP
cord-350019-4nlbu54e	15	3	provide	provide	VBP
cord-350019-4nlbu54e	15	4	a	a	DT
cord-350019-4nlbu54e	15	5	review	review	NN
cord-350019-4nlbu54e	15	6	of	of	IN
cord-350019-4nlbu54e	15	7	the	the	DT
cord-350019-4nlbu54e	15	8	approaches	approach	NNS
cord-350019-4nlbu54e	15	9	typically	typically	RB
cord-350019-4nlbu54e	15	10	adopted	adopt	VBN
cord-350019-4nlbu54e	15	11	to	to	TO
cord-350019-4nlbu54e	15	12	study	study	VB
cord-350019-4nlbu54e	15	13	the	the	DT
cord-350019-4nlbu54e	15	14	complexity	complexity	NN
cord-350019-4nlbu54e	15	15	of	of	IN
cord-350019-4nlbu54e	15	16	these	these	DT
cord-350019-4nlbu54e	15	17	genes	gene	NNS
cord-350019-4nlbu54e	15	18	with	with	IN
cord-350019-4nlbu54e	15	19	an	an	DT
cord-350019-4nlbu54e	15	20	emphasis	emphasis	NN
cord-350019-4nlbu54e	15	21	on	on	IN
cord-350019-4nlbu54e	15	22	recent	recent	JJ
cord-350019-4nlbu54e	15	23	discoveries	discovery	NNS
cord-350019-4nlbu54e	15	24	within	within	IN
cord-350019-4nlbu54e	15	25	the	the	DT
cord-350019-4nlbu54e	15	26	innate	innate	JJ
cord-350019-4nlbu54e	15	27	immune	immune	JJ
cord-350019-4nlbu54e	15	28	field	field	NN
cord-350019-4nlbu54e	15	29	.	.	.
cord-350019-4nlbu54e	16	1	Finally	finally	RB
cord-350019-4nlbu54e	16	2	,	,	,
cord-350019-4nlbu54e	16	3	we	-PRON-	PRP
cord-350019-4nlbu54e	16	4	discuss	discuss	VBP
cord-350019-4nlbu54e	16	5	the	the	DT
cord-350019-4nlbu54e	16	6	challenges	challenge	NNS
cord-350019-4nlbu54e	16	7	,	,	,
cord-350019-4nlbu54e	16	8	as	as	RB
cord-350019-4nlbu54e	16	9	well	well	RB
cord-350019-4nlbu54e	16	10	as	as	IN
cord-350019-4nlbu54e	16	11	the	the	DT
cord-350019-4nlbu54e	16	12	emergence	emergence	NN
cord-350019-4nlbu54e	16	13	of	of	IN
cord-350019-4nlbu54e	16	14	new	new	JJ
cord-350019-4nlbu54e	16	15	technologies	technology	NNS
cord-350019-4nlbu54e	16	16	that	that	WDT
cord-350019-4nlbu54e	16	17	will	will	MD
cord-350019-4nlbu54e	16	18	continue	continue	VB
cord-350019-4nlbu54e	16	19	to	to	TO
cord-350019-4nlbu54e	16	20	move	move	VB
cord-350019-4nlbu54e	16	21	this	this	DT
cord-350019-4nlbu54e	16	22	field	field	NN
cord-350019-4nlbu54e	16	23	forward	forward	RB
cord-350019-4nlbu54e	16	24	and	and	CC
cord-350019-4nlbu54e	16	25	provide	provide	VB
cord-350019-4nlbu54e	16	26	greater	great	JJR
cord-350019-4nlbu54e	16	27	insight	insight	NN
cord-350019-4nlbu54e	16	28	into	into	IN
cord-350019-4nlbu54e	16	29	the	the	DT
cord-350019-4nlbu54e	16	30	biological	biological	JJ
cord-350019-4nlbu54e	16	31	importance	importance	NN
cord-350019-4nlbu54e	16	32	of	of	IN
cord-350019-4nlbu54e	16	33	this	this	DT
cord-350019-4nlbu54e	16	34	class	class	NN
cord-350019-4nlbu54e	16	35	of	of	IN
cord-350019-4nlbu54e	16	36	genes	gene	NNS
cord-350019-4nlbu54e	16	37	.	.	.
cord-350019-4nlbu54e	17	1	This	this	DT
cord-350019-4nlbu54e	17	2	article	article	NN
cord-350019-4nlbu54e	17	3	is	be	VBZ
cord-350019-4nlbu54e	17	4	part	part	NN
cord-350019-4nlbu54e	17	5	of	of	IN
cord-350019-4nlbu54e	17	6	a	a	DT
cord-350019-4nlbu54e	17	7	Special	Special	NNP
cord-350019-4nlbu54e	17	8	Issue	Issue	NNP
cord-350019-4nlbu54e	17	9	entitled	entitle	VBN
cord-350019-4nlbu54e	17	10	:	:	:
cord-350019-4nlbu54e	17	11	ncRNA	ncRNA	.
cord-350019-4nlbu54e	18	1	in	in	IN
cord-350019-4nlbu54e	18	2	control	control	NN
cord-350019-4nlbu54e	18	3	of	of	IN
cord-350019-4nlbu54e	18	4	gene	gene	NN
cord-350019-4nlbu54e	18	5	expression	expression	NN
cord-350019-4nlbu54e	18	6	edited	edit	VBN
cord-350019-4nlbu54e	18	7	by	by	IN
cord-350019-4nlbu54e	18	8	Kotb	Kotb	NNP
cord-350019-4nlbu54e	18	9	Abdelmohsen	Abdelmohsen	NNP
cord-350019-4nlbu54e	18	10	.	.	.
cord-350019-4nlbu54e	19	1	One	one	CD
cord-350019-4nlbu54e	19	2	of	of	IN
cord-350019-4nlbu54e	19	3	the	the	DT
cord-350019-4nlbu54e	19	4	most	most	RBS
cord-350019-4nlbu54e	19	5	profound	profound	JJ
cord-350019-4nlbu54e	19	6	discoveries	discovery	NNS
cord-350019-4nlbu54e	19	7	from	from	IN
cord-350019-4nlbu54e	19	8	the	the	DT
cord-350019-4nlbu54e	19	9	sequencing	sequencing	NN
cord-350019-4nlbu54e	19	10	of	of	IN
cord-350019-4nlbu54e	19	11	the	the	DT
cord-350019-4nlbu54e	19	12	human	human	JJ
cord-350019-4nlbu54e	19	13	genome	genome	NN
cord-350019-4nlbu54e	19	14	is	be	VBZ
cord-350019-4nlbu54e	19	15	that	that	IN
cord-350019-4nlbu54e	19	16	over	over	IN
cord-350019-4nlbu54e	19	17	85	85	CD
cord-350019-4nlbu54e	19	18	%	%	NN
cord-350019-4nlbu54e	19	19	of	of	IN
cord-350019-4nlbu54e	19	20	the	the	DT
cord-350019-4nlbu54e	19	21	genome	genome	NN
cord-350019-4nlbu54e	19	22	is	be	VBZ
cord-350019-4nlbu54e	19	23	transcribed	transcribe	VBN
cord-350019-4nlbu54e	19	24	,	,	,
cord-350019-4nlbu54e	19	25	yet	yet	RB
cord-350019-4nlbu54e	19	26	<	<	XX
cord-350019-4nlbu54e	19	27	2	2	CD
cord-350019-4nlbu54e	19	28	%	%	NN
cord-350019-4nlbu54e	19	29	encodes	encode	VBZ
cord-350019-4nlbu54e	19	30	protein	protein	NN
cord-350019-4nlbu54e	19	31	-	-	HYPH
cord-350019-4nlbu54e	19	32	coding	code	VBG
cord-350019-4nlbu54e	19	33	genes	gene	NNS
cord-350019-4nlbu54e	19	34	[	[	-LRB-
cord-350019-4nlbu54e	19	35	1	1	CD
cord-350019-4nlbu54e	19	36	]	]	-RRB-
cord-350019-4nlbu54e	19	37	.	.	.
cord-350019-4nlbu54e	20	1	Large	large	JJ
cord-350019-4nlbu54e	20	2	consortiums	consortium	NNS
cord-350019-4nlbu54e	20	3	such	such	JJ
cord-350019-4nlbu54e	20	4	as	as	IN
cord-350019-4nlbu54e	20	5	ENCODE	ENCODE	NNP
cord-350019-4nlbu54e	20	6	and	and	CC
cord-350019-4nlbu54e	20	7	FANTOM	FANTOM	NNP
cord-350019-4nlbu54e	20	8	have	have	VBP
cord-350019-4nlbu54e	20	9	embarked	embark	VBN
cord-350019-4nlbu54e	20	10	on	on	IN
cord-350019-4nlbu54e	20	11	attempting	attempt	VBG
cord-350019-4nlbu54e	20	12	to	to	TO
cord-350019-4nlbu54e	20	13	characterize	characterize	VB
cord-350019-4nlbu54e	20	14	all	all	DT
cord-350019-4nlbu54e	20	15	functional	functional	JJ
cord-350019-4nlbu54e	20	16	coding	coding	NN
cord-350019-4nlbu54e	20	17	and	and	CC
cord-350019-4nlbu54e	20	18	noncoding	noncoding	JJ
cord-350019-4nlbu54e	20	19	elements	element	NNS
cord-350019-4nlbu54e	20	20	in	in	IN
cord-350019-4nlbu54e	20	21	the	the	DT
cord-350019-4nlbu54e	20	22	genome	genome	NN
cord-350019-4nlbu54e	20	23	and	and	CC
cord-350019-4nlbu54e	20	24	have	have	VBP
cord-350019-4nlbu54e	20	25	compiled	compile	VBN
cord-350019-4nlbu54e	20	26	important	important	JJ
cord-350019-4nlbu54e	20	27	regulatory	regulatory	JJ
cord-350019-4nlbu54e	20	28	data	datum	NNS
cord-350019-4nlbu54e	20	29	for	for	IN
cord-350019-4nlbu54e	20	30	these	these	DT
cord-350019-4nlbu54e	20	31	elements	element	NNS
cord-350019-4nlbu54e	20	32	[	[	-LRB-
cord-350019-4nlbu54e	20	33	2	2	CD
cord-350019-4nlbu54e	20	34	]	]	-RRB-
cord-350019-4nlbu54e	20	35	[	[	-LRB-
cord-350019-4nlbu54e	20	36	3	3	CD
cord-350019-4nlbu54e	20	37	]	]	-RRB-
cord-350019-4nlbu54e	20	38	[	[	-LRB-
cord-350019-4nlbu54e	20	39	4	4	CD
cord-350019-4nlbu54e	20	40	]	]	-RRB-
cord-350019-4nlbu54e	20	41	.	.	.
cord-350019-4nlbu54e	21	1	Long	long	JJ
cord-350019-4nlbu54e	21	2	noncoding	noncoding	JJ
cord-350019-4nlbu54e	21	3	RNAs	rna	NNS
cord-350019-4nlbu54e	21	4	(	(	-LRB-
cord-350019-4nlbu54e	21	5	lncRNAs	lncrnas	RB
cord-350019-4nlbu54e	21	6	)	)	-RRB-
cord-350019-4nlbu54e	21	7	represent	represent	VB
cord-350019-4nlbu54e	21	8	the	the	DT
cord-350019-4nlbu54e	21	9	largest	large	JJS
cord-350019-4nlbu54e	21	10	group	group	NN
cord-350019-4nlbu54e	21	11	of	of	IN
cord-350019-4nlbu54e	21	12	non	non	JJ
cord-350019-4nlbu54e	21	13	-	-	JJ
cord-350019-4nlbu54e	21	14	coding	coding	JJ
cord-350019-4nlbu54e	21	15	RNAs	rna	NNS
cord-350019-4nlbu54e	21	16	produced	produce	VBN
cord-350019-4nlbu54e	21	17	from	from	IN
cord-350019-4nlbu54e	21	18	the	the	DT
cord-350019-4nlbu54e	21	19	genome	genome	NN
cord-350019-4nlbu54e	21	20	.	.	.
cord-350019-4nlbu54e	22	1	LncRNAs	LncRNAs	NNP
cord-350019-4nlbu54e	22	2	are	be	VBP
cord-350019-4nlbu54e	22	3	defined	define	VBN
cord-350019-4nlbu54e	22	4	as	as	IN
cord-350019-4nlbu54e	22	5	transcripts	transcript	NNS
cord-350019-4nlbu54e	22	6	>	>	XX
cord-350019-4nlbu54e	22	7	200	200	CD
cord-350019-4nlbu54e	22	8	nucleotides	nucleotide	NNS
cord-350019-4nlbu54e	22	9	in	in	IN
cord-350019-4nlbu54e	22	10	length	length	NN
cord-350019-4nlbu54e	22	11	,	,	,
cord-350019-4nlbu54e	22	12	lacking	lack	VBG
cord-350019-4nlbu54e	22	13	protein	protein	NN
cord-350019-4nlbu54e	22	14	-	-	HYPH
cord-350019-4nlbu54e	22	15	coding	code	VBG
cord-350019-4nlbu54e	22	16	potential	potential	NN
cord-350019-4nlbu54e	22	17	.	.	.
cord-350019-4nlbu54e	23	1	In	in	IN
cord-350019-4nlbu54e	23	2	the	the	DT
cord-350019-4nlbu54e	23	3	most	most	RBS
cord-350019-4nlbu54e	23	4	recent	recent	JJ
cord-350019-4nlbu54e	23	5	GENCODE	GENCODE	NNP
cord-350019-4nlbu54e	23	6	V30	V30	NNP
cord-350019-4nlbu54e	23	7	release	release	NN
cord-350019-4nlbu54e	23	8	,	,	,
cord-350019-4nlbu54e	23	9	there	there	EX
cord-350019-4nlbu54e	23	10	are	be	VBP
cord-350019-4nlbu54e	23	11	16	16	CD
cord-350019-4nlbu54e	23	12	,	,	,
cord-350019-4nlbu54e	23	13	193	193	CD
cord-350019-4nlbu54e	23	14	annotated	annotate	VBN
cord-350019-4nlbu54e	23	15	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	23	16	in	in	IN
cord-350019-4nlbu54e	23	17	the	the	DT
cord-350019-4nlbu54e	23	18	human	human	JJ
cord-350019-4nlbu54e	23	19	genome	genome	NN
cord-350019-4nlbu54e	23	20	[	[	-LRB-
cord-350019-4nlbu54e	23	21	4	4	CD
cord-350019-4nlbu54e	23	22	]	]	-RRB-
cord-350019-4nlbu54e	23	23	.	.	.
cord-350019-4nlbu54e	24	1	Additionally	additionally	RB
cord-350019-4nlbu54e	24	2	,	,	,
cord-350019-4nlbu54e	24	3	there	there	EX
cord-350019-4nlbu54e	24	4	are	be	VBP
cord-350019-4nlbu54e	24	5	over	over	IN
cord-350019-4nlbu54e	24	6	14,000	14,000	CD
cord-350019-4nlbu54e	24	7	pseudogenes	pseudogene	NNS
cord-350019-4nlbu54e	24	8	,	,	,
cord-350019-4nlbu54e	24	9	that	that	WDT
cord-350019-4nlbu54e	24	10	could	could	MD
cord-350019-4nlbu54e	24	11	fall	fall	VB
cord-350019-4nlbu54e	24	12	under	under	IN
cord-350019-4nlbu54e	24	13	the	the	DT
cord-350019-4nlbu54e	24	14	description	description	NN
cord-350019-4nlbu54e	24	15	of	of	IN
cord-350019-4nlbu54e	24	16	long	long	JJ
cord-350019-4nlbu54e	24	17	noncoding	noncoding	JJ
cord-350019-4nlbu54e	24	18	RNAs	rna	NNS
cord-350019-4nlbu54e	24	19	which	which	WDT
cord-350019-4nlbu54e	24	20	is	be	VBZ
cord-350019-4nlbu54e	24	21	simply	simply	RB
cord-350019-4nlbu54e	24	22	based	base	VBN
cord-350019-4nlbu54e	24	23	on	on	IN
cord-350019-4nlbu54e	24	24	them	-PRON-	PRP
cord-350019-4nlbu54e	24	25	being	be	VBG
cord-350019-4nlbu54e	24	26	200	200	CD
cord-350019-4nlbu54e	24	27	nucleotides	nucleotide	NNS
cord-350019-4nlbu54e	24	28	or	or	CC
cord-350019-4nlbu54e	24	29	greater	great	JJR
cord-350019-4nlbu54e	24	30	in	in	IN
cord-350019-4nlbu54e	24	31	length	length	NN
cord-350019-4nlbu54e	24	32	.	.	.
cord-350019-4nlbu54e	25	1	Less	Less	JJR
cord-350019-4nlbu54e	25	2	than~3	than~3	IN
cord-350019-4nlbu54e	25	3	%	%	NN
cord-350019-4nlbu54e	25	4	of	of	IN
cord-350019-4nlbu54e	25	5	annotated	annotate	VBN
cord-350019-4nlbu54e	25	6	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	25	7	have	have	VBP
cord-350019-4nlbu54e	25	8	ascribed	ascribe	VBN
cord-350019-4nlbu54e	25	9	functions	function	NNS
cord-350019-4nlbu54e	25	10	.	.	.
cord-350019-4nlbu54e	26	1	Hence	hence	RB
cord-350019-4nlbu54e	26	2	this	this	DT
cord-350019-4nlbu54e	26	3	class	class	NN
cord-350019-4nlbu54e	26	4	of	of	IN
cord-350019-4nlbu54e	26	5	RNAs	rna	NNS
cord-350019-4nlbu54e	26	6	is	be	VBZ
cord-350019-4nlbu54e	26	7	greatly	greatly	RB
cord-350019-4nlbu54e	26	8	in	in	IN
cord-350019-4nlbu54e	26	9	need	need	NN
cord-350019-4nlbu54e	26	10	of	of	IN
cord-350019-4nlbu54e	26	11	further	further	JJ
cord-350019-4nlbu54e	26	12	investigation	investigation	NN
cord-350019-4nlbu54e	26	13	[	[	-LRB-
cord-350019-4nlbu54e	26	14	4	4	CD
cord-350019-4nlbu54e	26	15	]	]	-RRB-
cord-350019-4nlbu54e	26	16	.	.	.
cord-350019-4nlbu54e	27	1	From	from	IN
cord-350019-4nlbu54e	27	2	those	those	DT
cord-350019-4nlbu54e	27	3	that	that	WDT
cord-350019-4nlbu54e	27	4	have	have	VBP
cord-350019-4nlbu54e	27	5	been	be	VBN
cord-350019-4nlbu54e	27	6	characterized	characterize	VBN
cord-350019-4nlbu54e	27	7	,	,	,
cord-350019-4nlbu54e	27	8	it	-PRON-	PRP
cord-350019-4nlbu54e	27	9	is	be	VBZ
cord-350019-4nlbu54e	27	10	clear	clear	JJ
cord-350019-4nlbu54e	27	11	that	that	IN
cord-350019-4nlbu54e	27	12	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	27	13	can	can	MD
cord-350019-4nlbu54e	27	14	function	function	VB
cord-350019-4nlbu54e	27	15	through	through	IN
cord-350019-4nlbu54e	27	16	a	a	DT
cord-350019-4nlbu54e	27	17	variety	variety	NN
cord-350019-4nlbu54e	27	18	of	of	IN
cord-350019-4nlbu54e	27	19	mechanisms	mechanism	NNS
cord-350019-4nlbu54e	27	20	to	to	TO
cord-350019-4nlbu54e	27	21	regulate	regulate	VB
cord-350019-4nlbu54e	27	22	gene	gene	NN
cord-350019-4nlbu54e	27	23	expression	expression	NN
cord-350019-4nlbu54e	27	24	both	both	CC
cord-350019-4nlbu54e	27	25	at	at	IN
cord-350019-4nlbu54e	27	26	the	the	DT
cord-350019-4nlbu54e	27	27	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	27	28	and	and	CC
cord-350019-4nlbu54e	27	29	post	post	JJ
cord-350019-4nlbu54e	27	30	-	-	JJ
cord-350019-4nlbu54e	27	31	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	27	32	levels	level	NNS
cord-350019-4nlbu54e	27	33	[	[	-LRB-
cord-350019-4nlbu54e	27	34	5	5	CD
cord-350019-4nlbu54e	27	35	]	]	-RRB-
cord-350019-4nlbu54e	27	36	.	.	.
cord-350019-4nlbu54e	28	1	As	as	IN
cord-350019-4nlbu54e	28	2	we	-PRON-	PRP
cord-350019-4nlbu54e	28	3	will	will	MD
cord-350019-4nlbu54e	28	4	discuss	discuss	VB
cord-350019-4nlbu54e	28	5	through	through	IN
cord-350019-4nlbu54e	28	6	this	this	DT
cord-350019-4nlbu54e	28	7	review	review	NN
cord-350019-4nlbu54e	28	8	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	28	9	can	can	MD
cord-350019-4nlbu54e	28	10	mediate	mediate	VB
cord-350019-4nlbu54e	28	11	their	-PRON-	PRP$
cord-350019-4nlbu54e	28	12	functions	function	NNS
cord-350019-4nlbu54e	28	13	through	through	IN
cord-350019-4nlbu54e	28	14	interactions	interaction	NNS
cord-350019-4nlbu54e	28	15	with	with	IN
cord-350019-4nlbu54e	28	16	proteins	protein	NNS
cord-350019-4nlbu54e	28	17	,	,	,
cord-350019-4nlbu54e	28	18	RNA	RNA	NNP
cord-350019-4nlbu54e	28	19	,	,	,
cord-350019-4nlbu54e	28	20	DNA	DNA	NNP
cord-350019-4nlbu54e	28	21	,	,	,
cord-350019-4nlbu54e	28	22	or	or	CC
cord-350019-4nlbu54e	28	23	a	a	DT
cord-350019-4nlbu54e	28	24	combination	combination	NN
cord-350019-4nlbu54e	28	25	of	of	IN
cord-350019-4nlbu54e	28	26	these	these	DT
cord-350019-4nlbu54e	28	27	.	.	.
cord-350019-4nlbu54e	29	1	Furthermore	furthermore	RB
cord-350019-4nlbu54e	29	2	,	,	,
cord-350019-4nlbu54e	29	3	the	the	DT
cord-350019-4nlbu54e	29	4	function	function	NN
cord-350019-4nlbu54e	29	5	of	of	IN
cord-350019-4nlbu54e	29	6	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	29	7	can	can	MD
cord-350019-4nlbu54e	29	8	often	often	RB
cord-350019-4nlbu54e	29	9	be	be	VB
cord-350019-4nlbu54e	29	10	dictated	dictate	VBN
cord-350019-4nlbu54e	29	11	by	by	IN
cord-350019-4nlbu54e	29	12	their	-PRON-	PRP$
cord-350019-4nlbu54e	29	13	localization	localization	NN
cord-350019-4nlbu54e	29	14	,	,	,
cord-350019-4nlbu54e	29	15	sequence	sequence	NN
cord-350019-4nlbu54e	29	16	and/or	and/or	CC
cord-350019-4nlbu54e	29	17	secondary	secondary	JJ
cord-350019-4nlbu54e	29	18	structure	structure	NN
cord-350019-4nlbu54e	29	19	.	.	.
cord-350019-4nlbu54e	30	1	There	there	EX
cord-350019-4nlbu54e	30	2	are	be	VBP
cord-350019-4nlbu54e	30	3	many	many	JJ
cord-350019-4nlbu54e	30	4	categories	category	NNS
cord-350019-4nlbu54e	30	5	and	and	CC
cord-350019-4nlbu54e	30	6	sub	sub	NN
cord-350019-4nlbu54e	30	7	-	-	NNS
cord-350019-4nlbu54e	30	8	categories	category	NNS
cord-350019-4nlbu54e	30	9	of	of	IN
cord-350019-4nlbu54e	30	10	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	30	11	,	,	,
cord-350019-4nlbu54e	30	12	but	but	CC
cord-350019-4nlbu54e	30	13	some	some	DT
cord-350019-4nlbu54e	30	14	of	of	IN
cord-350019-4nlbu54e	30	15	the	the	DT
cord-350019-4nlbu54e	30	16	major	major	JJ
cord-350019-4nlbu54e	30	17	classifications	classification	NNS
cord-350019-4nlbu54e	30	18	include	include	VBP
cord-350019-4nlbu54e	30	19	:	:	:
cord-350019-4nlbu54e	30	20	antisense	antisense	NNP
cord-350019-4nlbu54e	30	21	[	[	-LRB-
cord-350019-4nlbu54e	30	22	6	6	CD
cord-350019-4nlbu54e	30	23	]	]	-RRB-
cord-350019-4nlbu54e	30	24	,	,	,
cord-350019-4nlbu54e	30	25	bi	bi	JJ
cord-350019-4nlbu54e	30	26	-	-	JJ
cord-350019-4nlbu54e	30	27	directional	directional	JJ
cord-350019-4nlbu54e	30	28	[	[	-LRB-
cord-350019-4nlbu54e	30	29	7	7	CD
cord-350019-4nlbu54e	30	30	]	]	-RRB-
cord-350019-4nlbu54e	30	31	,	,	,
cord-350019-4nlbu54e	30	32	enhancer	enhancer	NN
cord-350019-4nlbu54e	30	33	-	-	HYPH
cord-350019-4nlbu54e	30	34	associated	associate	VBN
cord-350019-4nlbu54e	30	35	[	[	-LRB-
cord-350019-4nlbu54e	30	36	8	8	CD
cord-350019-4nlbu54e	30	37	]	]	-RRB-
cord-350019-4nlbu54e	30	38	,	,	,
cord-350019-4nlbu54e	30	39	intergenic	intergenic	JJ
cord-350019-4nlbu54e	30	40	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	30	41	(	(	-LRB-
cord-350019-4nlbu54e	30	42	lincRNAs	lincrnas	RB
cord-350019-4nlbu54e	30	43	)	)	-RRB-
cord-350019-4nlbu54e	30	44	[	[	-LRB-
cord-350019-4nlbu54e	30	45	9	9	CD
cord-350019-4nlbu54e	30	46	]	]	-RRB-
cord-350019-4nlbu54e	30	47	,	,	,
cord-350019-4nlbu54e	30	48	pseudogenes	pseudogene	NNS
cord-350019-4nlbu54e	30	49	[	[	-LRB-
cord-350019-4nlbu54e	30	50	10	10	CD
cord-350019-4nlbu54e	30	51	]	]	-RRB-
cord-350019-4nlbu54e	30	52	,	,	,
cord-350019-4nlbu54e	30	53	while	while	IN
cord-350019-4nlbu54e	30	54	a	a	DT
cord-350019-4nlbu54e	30	55	full	full	JJ
cord-350019-4nlbu54e	30	56	review	review	NN
cord-350019-4nlbu54e	30	57	of	of	IN
cord-350019-4nlbu54e	30	58	all	all	DT
cord-350019-4nlbu54e	30	59	classifications	classification	NNS
cord-350019-4nlbu54e	30	60	can	can	MD
cord-350019-4nlbu54e	30	61	be	be	VB
cord-350019-4nlbu54e	30	62	obtained	obtain	VBN
cord-350019-4nlbu54e	30	63	from	from	IN
cord-350019-4nlbu54e	30	64	the	the	DT
cord-350019-4nlbu54e	30	65	recent	recent	JJ
cord-350019-4nlbu54e	30	66	review	review	NN
cord-350019-4nlbu54e	30	67	by	by	IN
cord-350019-4nlbu54e	30	68	Jarroux	Jarroux	NNP
cord-350019-4nlbu54e	30	69	et	et	NNP
cord-350019-4nlbu54e	30	70	al	al	NNP
cord-350019-4nlbu54e	30	71	.	.	.
cord-350019-4nlbu54e	31	1	[	[	-LRB-
cord-350019-4nlbu54e	31	2	11	11	CD
cord-350019-4nlbu54e	31	3	]	]	-RRB-
cord-350019-4nlbu54e	31	4	.	.	.
cord-350019-4nlbu54e	32	1	LncRNA	LncRNA	NNS
cord-350019-4nlbu54e	32	2	function	function	NN
cord-350019-4nlbu54e	32	3	can	can	MD
cord-350019-4nlbu54e	32	4	not	not	RB
cord-350019-4nlbu54e	32	5	be	be	VB
cord-350019-4nlbu54e	32	6	determined	determine	VBN
cord-350019-4nlbu54e	32	7	simply	simply	RB
cord-350019-4nlbu54e	32	8	based	base	VBN
cord-350019-4nlbu54e	32	9	on	on	IN
cord-350019-4nlbu54e	32	10	the	the	DT
cord-350019-4nlbu54e	32	11	lncRNA	lncrna	NN
cord-350019-4nlbu54e	32	12	classification	classification	NN
cord-350019-4nlbu54e	32	13	.	.	.
cord-350019-4nlbu54e	33	1	However	however	RB
cord-350019-4nlbu54e	33	2	,	,	,
cord-350019-4nlbu54e	33	3	the	the	DT
cord-350019-4nlbu54e	33	4	classification	classification	NN
cord-350019-4nlbu54e	33	5	can	can	MD
cord-350019-4nlbu54e	33	6	sometimes	sometimes	RB
cord-350019-4nlbu54e	33	7	provide	provide	VB
cord-350019-4nlbu54e	33	8	insight	insight	NN
cord-350019-4nlbu54e	33	9	into	into	IN
cord-350019-4nlbu54e	33	10	its	-PRON-	PRP$
cord-350019-4nlbu54e	33	11	mechanism	mechanism	NN
cord-350019-4nlbu54e	33	12	of	of	IN
cord-350019-4nlbu54e	33	13	action	action	NN
cord-350019-4nlbu54e	33	14	,	,	,
cord-350019-4nlbu54e	33	15	such	such	JJ
cord-350019-4nlbu54e	33	16	as	as	IN
cord-350019-4nlbu54e	33	17	antisense	antisense	NN
cord-350019-4nlbu54e	33	18	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	33	19	impacting	impact	VBG
cord-350019-4nlbu54e	33	20	their	-PRON-	PRP$
cord-350019-4nlbu54e	33	21	neighboring	neighboring	JJ
cord-350019-4nlbu54e	33	22	genes	gene	NNS
cord-350019-4nlbu54e	33	23	.	.	.
cord-350019-4nlbu54e	34	1	However	however	RB
cord-350019-4nlbu54e	34	2	,	,	,
cord-350019-4nlbu54e	34	3	this	this	DT
cord-350019-4nlbu54e	34	4	same	same	JJ
cord-350019-4nlbu54e	34	5	classification	classification	NN
cord-350019-4nlbu54e	34	6	can	can	MD
cord-350019-4nlbu54e	34	7	also	also	RB
cord-350019-4nlbu54e	34	8	lead	lead	VB
cord-350019-4nlbu54e	34	9	to	to	IN
cord-350019-4nlbu54e	34	10	erroneous	erroneous	JJ
cord-350019-4nlbu54e	34	11	assumptions	assumption	NNS
cord-350019-4nlbu54e	34	12	about	about	IN
cord-350019-4nlbu54e	34	13	how	how	WRB
cord-350019-4nlbu54e	34	14	the	the	DT
cord-350019-4nlbu54e	34	15	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	34	16	regulates	regulate	VBZ
cord-350019-4nlbu54e	34	17	gene	gene	NN
cord-350019-4nlbu54e	34	18	expression	expression	NN
cord-350019-4nlbu54e	34	19	.	.	.
cord-350019-4nlbu54e	35	1	Recently	recently	RB
cord-350019-4nlbu54e	35	2	,	,	,
cord-350019-4nlbu54e	35	3	some	some	DT
cord-350019-4nlbu54e	35	4	lncRNAs	lncrnas	UH
cord-350019-4nlbu54e	35	5	have	have	VBP
cord-350019-4nlbu54e	35	6	been	be	VBN
cord-350019-4nlbu54e	35	7	demonstrated	demonstrate	VBN
cord-350019-4nlbu54e	35	8	to	to	TO
cord-350019-4nlbu54e	35	9	actually	actually	RB
cord-350019-4nlbu54e	35	10	encode	encode	VB
cord-350019-4nlbu54e	35	11	small	small	JJ
cord-350019-4nlbu54e	35	12	peptides	peptide	NNS
cord-350019-4nlbu54e	35	13	indicating	indicate	VBG
cord-350019-4nlbu54e	35	14	that	that	IN
cord-350019-4nlbu54e	35	15	these	these	DT
cord-350019-4nlbu54e	35	16	genes	gene	NNS
cord-350019-4nlbu54e	35	17	are	be	VBP
cord-350019-4nlbu54e	35	18	misclassified	misclassifie	VBN
cord-350019-4nlbu54e	35	19	as	as	IN
cord-350019-4nlbu54e	35	20	noncoding	noncoding	JJ
cord-350019-4nlbu54e	35	21	,	,	,
cord-350019-4nlbu54e	35	22	although	although	IN
cord-350019-4nlbu54e	35	23	it	-PRON-	PRP
cord-350019-4nlbu54e	35	24	is	be	VBZ
cord-350019-4nlbu54e	35	25	possible	possible	JJ
cord-350019-4nlbu54e	35	26	that	that	IN
cord-350019-4nlbu54e	35	27	they	-PRON-	PRP
cord-350019-4nlbu54e	35	28	could	could	MD
cord-350019-4nlbu54e	35	29	also	also	RB
cord-350019-4nlbu54e	35	30	have	have	VB
cord-350019-4nlbu54e	35	31	functions	function	NNS
cord-350019-4nlbu54e	35	32	as	as	IN
cord-350019-4nlbu54e	35	33	a	a	DT
cord-350019-4nlbu54e	35	34	noncoding	noncoding	JJ
cord-350019-4nlbu54e	35	35	RNA	RNA	NNP
cord-350019-4nlbu54e	35	36	in	in	IN
cord-350019-4nlbu54e	35	37	addition	addition	NN
cord-350019-4nlbu54e	35	38	to	to	IN
cord-350019-4nlbu54e	35	39	their	-PRON-	PRP$
cord-350019-4nlbu54e	35	40	peptide	peptide	NN
cord-350019-4nlbu54e	35	41	coding	coding	NN
cord-350019-4nlbu54e	35	42	capacity	capacity	NN
cord-350019-4nlbu54e	35	43	[	[	-LRB-
cord-350019-4nlbu54e	35	44	12	12	CD
cord-350019-4nlbu54e	35	45	]	]	-RRB-
cord-350019-4nlbu54e	35	46	[	[	-LRB-
cord-350019-4nlbu54e	35	47	13	13	CD
cord-350019-4nlbu54e	35	48	]	]	-RRB-
cord-350019-4nlbu54e	35	49	[	[	-LRB-
cord-350019-4nlbu54e	35	50	14	14	CD
cord-350019-4nlbu54e	35	51	]	]	-RRB-
cord-350019-4nlbu54e	35	52	[	[	-LRB-
cord-350019-4nlbu54e	35	53	15	15	CD
cord-350019-4nlbu54e	35	54	]	]	-RRB-
cord-350019-4nlbu54e	35	55	[	[	-LRB-
cord-350019-4nlbu54e	35	56	16	16	CD
cord-350019-4nlbu54e	35	57	]	]	-RRB-
cord-350019-4nlbu54e	35	58	[	[	-LRB-
cord-350019-4nlbu54e	35	59	17	17	CD
cord-350019-4nlbu54e	35	60	]	]	-RRB-
cord-350019-4nlbu54e	35	61	.	.	.
cord-350019-4nlbu54e	36	1	It	-PRON-	PRP
cord-350019-4nlbu54e	36	2	is	be	VBZ
cord-350019-4nlbu54e	36	3	therefore	therefore	RB
cord-350019-4nlbu54e	36	4	,	,	,
cord-350019-4nlbu54e	36	5	important	important	JJ
cord-350019-4nlbu54e	36	6	to	to	TO
cord-350019-4nlbu54e	36	7	have	have	VB
cord-350019-4nlbu54e	36	8	a	a	DT
cord-350019-4nlbu54e	36	9	logical	logical	JJ
cord-350019-4nlbu54e	36	10	methodology	methodology	NN
cord-350019-4nlbu54e	36	11	to	to	TO
cord-350019-4nlbu54e	36	12	study	study	VB
cord-350019-4nlbu54e	36	13	the	the	DT
cord-350019-4nlbu54e	36	14	biological	biological	JJ
cord-350019-4nlbu54e	36	15	importance	importance	NN
cord-350019-4nlbu54e	36	16	of	of	IN
cord-350019-4nlbu54e	36	17	these	these	DT
cord-350019-4nlbu54e	36	18	genes	gene	NNS
cord-350019-4nlbu54e	36	19	.	.	.
cord-350019-4nlbu54e	37	1	The	the	DT
cord-350019-4nlbu54e	37	2	innate	innate	JJ
cord-350019-4nlbu54e	37	3	immune	immune	JJ
cord-350019-4nlbu54e	37	4	system	system	NN
cord-350019-4nlbu54e	37	5	functions	function	NNS
cord-350019-4nlbu54e	37	6	as	as	IN
cord-350019-4nlbu54e	37	7	a	a	DT
cord-350019-4nlbu54e	37	8	rapid	rapid	JJ
cord-350019-4nlbu54e	37	9	initial	initial	JJ
cord-350019-4nlbu54e	37	10	response	response	NN
cord-350019-4nlbu54e	37	11	against	against	IN
cord-350019-4nlbu54e	37	12	specific	specific	JJ
cord-350019-4nlbu54e	37	13	pathogens	pathogen	NNS
cord-350019-4nlbu54e	37	14	,	,	,
cord-350019-4nlbu54e	37	15	while	while	IN
cord-350019-4nlbu54e	37	16	also	also	RB
cord-350019-4nlbu54e	37	17	promoting	promote	VBG
cord-350019-4nlbu54e	37	18	the	the	DT
cord-350019-4nlbu54e	37	19	activation	activation	NN
cord-350019-4nlbu54e	37	20	and	and	CC
cord-350019-4nlbu54e	37	21	development	development	NN
cord-350019-4nlbu54e	37	22	of	of	IN
cord-350019-4nlbu54e	37	23	the	the	DT
cord-350019-4nlbu54e	37	24	adaptive	adaptive	JJ
cord-350019-4nlbu54e	37	25	immune	immune	JJ
cord-350019-4nlbu54e	37	26	system	system	NN
cord-350019-4nlbu54e	37	27	[	[	-LRB-
cord-350019-4nlbu54e	37	28	18	18	CD
cord-350019-4nlbu54e	37	29	]	]	-RRB-
cord-350019-4nlbu54e	37	30	.	.	.
cord-350019-4nlbu54e	38	1	Macrophages	macrophage	NNS
cord-350019-4nlbu54e	38	2	and	and	CC
cord-350019-4nlbu54e	38	3	dendritic	dendritic	JJ
cord-350019-4nlbu54e	38	4	cells	cell	NNS
cord-350019-4nlbu54e	38	5	are	be	VBP
cord-350019-4nlbu54e	38	6	important	important	JJ
cord-350019-4nlbu54e	38	7	innate	innate	JJ
cord-350019-4nlbu54e	38	8	immune	immune	JJ
cord-350019-4nlbu54e	38	9	cells	cell	NNS
cord-350019-4nlbu54e	38	10	that	that	WDT
cord-350019-4nlbu54e	38	11	initiate	initiate	VBP
cord-350019-4nlbu54e	38	12	the	the	DT
cord-350019-4nlbu54e	38	13	immune	immune	JJ
cord-350019-4nlbu54e	38	14	response	response	NN
cord-350019-4nlbu54e	38	15	through	through	IN
cord-350019-4nlbu54e	38	16	recognition	recognition	NN
cord-350019-4nlbu54e	38	17	of	of	IN
cord-350019-4nlbu54e	38	18	specific	specific	JJ
cord-350019-4nlbu54e	38	19	pathogen	pathogen	NN
cord-350019-4nlbu54e	38	20	-	-	HYPH
cord-350019-4nlbu54e	38	21	associated	associate	VBN
cord-350019-4nlbu54e	38	22	molecular	molecular	JJ
cord-350019-4nlbu54e	38	23	patterns	pattern	NNS
cord-350019-4nlbu54e	38	24	(	(	-LRB-
cord-350019-4nlbu54e	38	25	PAMPs	pamp	NNS
cord-350019-4nlbu54e	38	26	)	)	-RRB-
cord-350019-4nlbu54e	38	27	through	through	IN
cord-350019-4nlbu54e	38	28	their	-PRON-	PRP$
cord-350019-4nlbu54e	38	29	germline	germline	NN
cord-350019-4nlbu54e	38	30	-	-	HYPH
cord-350019-4nlbu54e	38	31	encoded	encode	VBN
cord-350019-4nlbu54e	38	32	pattern	pattern	NN
cord-350019-4nlbu54e	38	33	recognition	recognition	NN
cord-350019-4nlbu54e	38	34	receptors	receptor	NNS
cord-350019-4nlbu54e	38	35	(	(	-LRB-
cord-350019-4nlbu54e	38	36	PRRs	PRRs	NNP
cord-350019-4nlbu54e	38	37	)	)	-RRB-
cord-350019-4nlbu54e	39	1	[	[	-LRB-
cord-350019-4nlbu54e	39	2	18	18	CD
cord-350019-4nlbu54e	39	3	]	]	-RRB-
cord-350019-4nlbu54e	39	4	.	.	.
cord-350019-4nlbu54e	40	1	These	these	DT
cord-350019-4nlbu54e	40	2	receptors	receptor	NNS
cord-350019-4nlbu54e	40	3	couple	couple	VBP
cord-350019-4nlbu54e	40	4	pathogensensing	pathogensense	VBG
cord-350019-4nlbu54e	40	5	to	to	IN
cord-350019-4nlbu54e	40	6	activation	activation	NN
cord-350019-4nlbu54e	40	7	of	of	IN
cord-350019-4nlbu54e	40	8	downstream	downstream	JJ
cord-350019-4nlbu54e	40	9	signaling	signaling	NN
cord-350019-4nlbu54e	40	10	cascades	cascade	NNS
cord-350019-4nlbu54e	40	11	resulting	result	VBG
cord-350019-4nlbu54e	40	12	in	in	IN
cord-350019-4nlbu54e	40	13	upregulation	upregulation	NN
cord-350019-4nlbu54e	40	14	of	of	IN
cord-350019-4nlbu54e	40	15	numerous	numerous	JJ
cord-350019-4nlbu54e	40	16	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	40	17	pathways	pathway	NNS
cord-350019-4nlbu54e	40	18	[	[	-LRB-
cord-350019-4nlbu54e	40	19	19	19	CD
cord-350019-4nlbu54e	40	20	]	]	-RRB-
cord-350019-4nlbu54e	40	21	.	.	.
cord-350019-4nlbu54e	41	1	While	while	IN
cord-350019-4nlbu54e	41	2	a	a	DT
cord-350019-4nlbu54e	41	3	robust	robust	JJ
cord-350019-4nlbu54e	41	4	immune	immune	JJ
cord-350019-4nlbu54e	41	5	response	response	NN
cord-350019-4nlbu54e	41	6	is	be	VBZ
cord-350019-4nlbu54e	41	7	crucial	crucial	JJ
cord-350019-4nlbu54e	41	8	for	for	IN
cord-350019-4nlbu54e	41	9	eliminating	eliminate	VBG
cord-350019-4nlbu54e	41	10	pathogens	pathogen	NNS
cord-350019-4nlbu54e	41	11	,	,	,
cord-350019-4nlbu54e	41	12	prolonged	prolonged	JJ
cord-350019-4nlbu54e	41	13	activation	activation	NN
cord-350019-4nlbu54e	41	14	can	can	MD
cord-350019-4nlbu54e	41	15	be	be	VB
cord-350019-4nlbu54e	41	16	detrimental	detrimental	JJ
cord-350019-4nlbu54e	41	17	to	to	IN
cord-350019-4nlbu54e	41	18	the	the	DT
cord-350019-4nlbu54e	41	19	host	host	NN
cord-350019-4nlbu54e	41	20	[	[	-LRB-
cord-350019-4nlbu54e	41	21	20	20	CD
cord-350019-4nlbu54e	41	22	]	]	-RRB-
cord-350019-4nlbu54e	41	23	.	.	.
cord-350019-4nlbu54e	42	1	Not	not	RB
cord-350019-4nlbu54e	42	2	surprisingly	surprisingly	RB
cord-350019-4nlbu54e	42	3	,	,	,
cord-350019-4nlbu54e	42	4	many	many	JJ
cord-350019-4nlbu54e	42	5	aspects	aspect	NNS
cord-350019-4nlbu54e	42	6	of	of	IN
cord-350019-4nlbu54e	42	7	the	the	DT
cord-350019-4nlbu54e	42	8	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	42	9	response	response	NN
cord-350019-4nlbu54e	42	10	are	be	VBP
cord-350019-4nlbu54e	42	11	tightly	tightly	RB
cord-350019-4nlbu54e	42	12	regulated	regulate	VBN
cord-350019-4nlbu54e	42	13	at	at	IN
cord-350019-4nlbu54e	42	14	both	both	DT
cord-350019-4nlbu54e	42	15	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	42	16	and	and	CC
cord-350019-4nlbu54e	42	17	post	post	JJ
cord-350019-4nlbu54e	42	18	-	-	JJ
cord-350019-4nlbu54e	42	19	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	42	20	levels	level	NNS
cord-350019-4nlbu54e	42	21	allowing	allow	VBG
cord-350019-4nlbu54e	42	22	for	for	IN
cord-350019-4nlbu54e	42	23	a	a	DT
cord-350019-4nlbu54e	42	24	transient	transient	JJ
cord-350019-4nlbu54e	42	25	antimicrobial	antimicrobial	JJ
cord-350019-4nlbu54e	42	26	response	response	NN
cord-350019-4nlbu54e	42	27	while	while	IN
cord-350019-4nlbu54e	42	28	subsequently	subsequently	RB
cord-350019-4nlbu54e	42	29	promoting	promote	VBG
cord-350019-4nlbu54e	42	30	a	a	DT
cord-350019-4nlbu54e	42	31	return	return	NN
cord-350019-4nlbu54e	42	32	to	to	IN
cord-350019-4nlbu54e	42	33	homeostasis	homeostasis	NN
cord-350019-4nlbu54e	42	34	[	[	-LRB-
cord-350019-4nlbu54e	42	35	21	21	CD
cord-350019-4nlbu54e	42	36	]	]	-RRB-
cord-350019-4nlbu54e	42	37	.	.	.
cord-350019-4nlbu54e	43	1	Perturbations	perturbation	NNS
cord-350019-4nlbu54e	43	2	in	in	IN
cord-350019-4nlbu54e	43	3	this	this	DT
cord-350019-4nlbu54e	43	4	regulation	regulation	NN
cord-350019-4nlbu54e	43	5	can	can	MD
cord-350019-4nlbu54e	43	6	have	have	VB
cord-350019-4nlbu54e	43	7	significant	significant	JJ
cord-350019-4nlbu54e	43	8	consequences	consequence	NNS
cord-350019-4nlbu54e	43	9	that	that	WDT
cord-350019-4nlbu54e	43	10	can	can	MD
cord-350019-4nlbu54e	43	11	manifest	manifest	VB
cord-350019-4nlbu54e	43	12	in	in	IN
cord-350019-4nlbu54e	43	13	diseases	disease	NNS
cord-350019-4nlbu54e	43	14	,	,	,
cord-350019-4nlbu54e	43	15	such	such	JJ
cord-350019-4nlbu54e	43	16	as	as	IN
cord-350019-4nlbu54e	43	17	arthritis	arthritis	NN
cord-350019-4nlbu54e	43	18	[	[	-LRB-
cord-350019-4nlbu54e	43	19	22	22	CD
cord-350019-4nlbu54e	43	20	]	]	-RRB-
cord-350019-4nlbu54e	43	21	,	,	,
cord-350019-4nlbu54e	43	22	multiple	multiple	JJ
cord-350019-4nlbu54e	43	23	sclerosis	sclerosis	NN
cord-350019-4nlbu54e	43	24	[	[	-LRB-
cord-350019-4nlbu54e	43	25	23	23	CD
cord-350019-4nlbu54e	43	26	]	]	-RRB-
cord-350019-4nlbu54e	43	27	and	and	CC
cord-350019-4nlbu54e	43	28	cancer	cancer	NN
cord-350019-4nlbu54e	43	29	[	[	-LRB-
cord-350019-4nlbu54e	43	30	20	20	CD
cord-350019-4nlbu54e	43	31	,	,	,
cord-350019-4nlbu54e	43	32	24	24	CD
cord-350019-4nlbu54e	43	33	]	]	-RRB-
cord-350019-4nlbu54e	43	34	.	.	.
cord-350019-4nlbu54e	44	1	While	while	IN
cord-350019-4nlbu54e	44	2	the	the	DT
cord-350019-4nlbu54e	44	3	role	role	NN
cord-350019-4nlbu54e	44	4	of	of	IN
cord-350019-4nlbu54e	44	5	coding	code	VBG
cord-350019-4nlbu54e	44	6	genes	gene	NNS
cord-350019-4nlbu54e	44	7	in	in	IN
cord-350019-4nlbu54e	44	8	immune	immune	JJ
cord-350019-4nlbu54e	44	9	cell	cell	NN
cord-350019-4nlbu54e	44	10	function	function	NN
cord-350019-4nlbu54e	44	11	has	have	VBZ
cord-350019-4nlbu54e	44	12	been	be	VBN
cord-350019-4nlbu54e	44	13	well	well	RB
cord-350019-4nlbu54e	44	14	characterized	characterize	VBN
cord-350019-4nlbu54e	44	15	,	,	,
cord-350019-4nlbu54e	44	16	the	the	DT
cord-350019-4nlbu54e	44	17	role	role	NN
cord-350019-4nlbu54e	44	18	of	of	IN
cord-350019-4nlbu54e	44	19	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	44	20	in	in	IN
cord-350019-4nlbu54e	44	21	these	these	DT
cord-350019-4nlbu54e	44	22	processes	process	NNS
cord-350019-4nlbu54e	44	23	is	be	VBZ
cord-350019-4nlbu54e	44	24	just	just	RB
cord-350019-4nlbu54e	44	25	beginning	begin	VBG
cord-350019-4nlbu54e	44	26	to	to	TO
cord-350019-4nlbu54e	44	27	emerge	emerge	VB
cord-350019-4nlbu54e	44	28	[	[	-LRB-
cord-350019-4nlbu54e	44	29	25	25	CD
cord-350019-4nlbu54e	44	30	]	]	-RRB-
cord-350019-4nlbu54e	45	1	(	(	-LRB-
cord-350019-4nlbu54e	45	2	Fig	Fig	NNP
cord-350019-4nlbu54e	45	3	.	.	.
cord-350019-4nlbu54e	46	1	1	1	LS
cord-350019-4nlbu54e	46	2	)	)	-RRB-
cord-350019-4nlbu54e	46	3	.	.	.
cord-350019-4nlbu54e	47	1	Here	here	RB
cord-350019-4nlbu54e	47	2	,	,	,
cord-350019-4nlbu54e	47	3	we	-PRON-	PRP
cord-350019-4nlbu54e	47	4	use	use	VBP
cord-350019-4nlbu54e	47	5	the	the	DT
cord-350019-4nlbu54e	47	6	biological	biological	JJ
cord-350019-4nlbu54e	47	7	model	model	NN
cord-350019-4nlbu54e	47	8	system	system	NN
cord-350019-4nlbu54e	47	9	of	of	IN
cord-350019-4nlbu54e	47	10	macrophage	macrophage	NN
cord-350019-4nlbu54e	47	11	activation	activation	NN
cord-350019-4nlbu54e	47	12	as	as	IN
cord-350019-4nlbu54e	47	13	a	a	DT
cord-350019-4nlbu54e	47	14	framework	framework	NN
cord-350019-4nlbu54e	47	15	to	to	TO
cord-350019-4nlbu54e	47	16	demonstrate	demonstrate	VB
cord-350019-4nlbu54e	47	17	how	how	WRB
cord-350019-4nlbu54e	47	18	we	-PRON-	PRP
cord-350019-4nlbu54e	47	19	approach	approach	VBP
cord-350019-4nlbu54e	47	20	the	the	DT
cord-350019-4nlbu54e	47	21	study	study	NN
cord-350019-4nlbu54e	47	22	of	of	IN
cord-350019-4nlbu54e	47	23	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	47	24	biology	biology	NN
cord-350019-4nlbu54e	47	25	.	.	.
cord-350019-4nlbu54e	48	1	We	-PRON-	PRP
cord-350019-4nlbu54e	48	2	provide	provide	VBP
cord-350019-4nlbu54e	48	3	a	a	DT
cord-350019-4nlbu54e	48	4	step	step	NN
cord-350019-4nlbu54e	48	5	-	-	HYPH
cord-350019-4nlbu54e	48	6	by	by	IN
cord-350019-4nlbu54e	48	7	-	-	HYPH
cord-350019-4nlbu54e	48	8	step	step	NN
cord-350019-4nlbu54e	48	9	guide	guide	NN
cord-350019-4nlbu54e	48	10	to	to	TO
cord-350019-4nlbu54e	48	11	consider	consider	VB
cord-350019-4nlbu54e	48	12	when	when	WRB
cord-350019-4nlbu54e	48	13	studying	study	VBG
cord-350019-4nlbu54e	48	14	lncRNAs	lncrnas	UH
cord-350019-4nlbu54e	48	15	.	.	.
cord-350019-4nlbu54e	49	1	Furthermore	furthermore	RB
cord-350019-4nlbu54e	49	2	,	,	,
cord-350019-4nlbu54e	49	3	we	-PRON-	PRP
cord-350019-4nlbu54e	49	4	discuss	discuss	VBP
cord-350019-4nlbu54e	49	5	the	the	DT
cord-350019-4nlbu54e	49	6	challenges	challenge	NNS
cord-350019-4nlbu54e	49	7	,	,	,
cord-350019-4nlbu54e	49	8	as	as	RB
cord-350019-4nlbu54e	49	9	well	well	RB
cord-350019-4nlbu54e	49	10	as	as	IN
cord-350019-4nlbu54e	49	11	the	the	DT
cord-350019-4nlbu54e	49	12	emergence	emergence	NN
cord-350019-4nlbu54e	49	13	of	of	IN
cord-350019-4nlbu54e	49	14	new	new	JJ
cord-350019-4nlbu54e	49	15	technologies	technology	NNS
cord-350019-4nlbu54e	49	16	that	that	WDT
cord-350019-4nlbu54e	49	17	are	be	VBP
cord-350019-4nlbu54e	49	18	helping	help	VBG
cord-350019-4nlbu54e	49	19	evolve	evolve	VB
cord-350019-4nlbu54e	49	20	the	the	DT
cord-350019-4nlbu54e	49	21	ways	way	NNS
cord-350019-4nlbu54e	49	22	we	-PRON-	PRP
cord-350019-4nlbu54e	49	23	study	study	VBP
cord-350019-4nlbu54e	49	24	these	these	DT
cord-350019-4nlbu54e	49	25	genes	gene	NNS
cord-350019-4nlbu54e	49	26	.	.	.
cord-350019-4nlbu54e	50	1	The	the	DT
cord-350019-4nlbu54e	50	2	lncRNA	lncrna	NN
cord-350019-4nlbu54e	50	3	field	field	NN
cord-350019-4nlbu54e	50	4	is	be	VBZ
cord-350019-4nlbu54e	50	5	in	in	IN
cord-350019-4nlbu54e	50	6	its	-PRON-	PRP$
cord-350019-4nlbu54e	50	7	infancy	infancy	NN
cord-350019-4nlbu54e	50	8	yet	yet	RB
cord-350019-4nlbu54e	50	9	from	from	IN
cord-350019-4nlbu54e	50	10	what	what	WP
cord-350019-4nlbu54e	50	11	we	-PRON-	PRP
cord-350019-4nlbu54e	50	12	do	do	VBP
cord-350019-4nlbu54e	50	13	know	know	VB
cord-350019-4nlbu54e	50	14	we	-PRON-	PRP
cord-350019-4nlbu54e	50	15	find	find	VBP
cord-350019-4nlbu54e	50	16	that	that	IN
cord-350019-4nlbu54e	50	17	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	50	18	play	play	VB
cord-350019-4nlbu54e	50	19	critical	critical	JJ
cord-350019-4nlbu54e	50	20	roles	role	NNS
cord-350019-4nlbu54e	50	21	in	in	IN
cord-350019-4nlbu54e	50	22	a	a	DT
cord-350019-4nlbu54e	50	23	wide	wide	JJ
cord-350019-4nlbu54e	50	24	variety	variety	NN
cord-350019-4nlbu54e	50	25	of	of	IN
cord-350019-4nlbu54e	50	26	biological	biological	JJ
cord-350019-4nlbu54e	50	27	processes	process	NNS
cord-350019-4nlbu54e	50	28	and	and	CC
cord-350019-4nlbu54e	50	29	diseases	disease	NNS
cord-350019-4nlbu54e	50	30	from	from	IN
cord-350019-4nlbu54e	50	31	cell	cell	NN
cord-350019-4nlbu54e	50	32	differentiation	differentiation	NN
cord-350019-4nlbu54e	50	33	,	,	,
cord-350019-4nlbu54e	50	34	tissue	tissue	NN
cord-350019-4nlbu54e	50	35	organ	organ	NN
cord-350019-4nlbu54e	50	36	development	development	NN
cord-350019-4nlbu54e	50	37	,	,	,
cord-350019-4nlbu54e	50	38	flowering	flower	VBG
cord-350019-4nlbu54e	50	39	in	in	IN
cord-350019-4nlbu54e	50	40	plants	plant	NNS
cord-350019-4nlbu54e	50	41	,	,	,
cord-350019-4nlbu54e	50	42	to	to	IN
cord-350019-4nlbu54e	50	43	cancer	cancer	NN
cord-350019-4nlbu54e	50	44	metastasis	metastasis	NN
cord-350019-4nlbu54e	50	45	to	to	TO
cord-350019-4nlbu54e	50	46	name	name	VB
cord-350019-4nlbu54e	50	47	just	just	RB
cord-350019-4nlbu54e	50	48	a	a	DT
cord-350019-4nlbu54e	50	49	few	few	JJ
cord-350019-4nlbu54e	50	50	[	[	-LRB-
cord-350019-4nlbu54e	50	51	26	26	CD
cord-350019-4nlbu54e	50	52	]	]	-RRB-
cord-350019-4nlbu54e	51	1	[	[	-LRB-
cord-350019-4nlbu54e	51	2	27	27	CD
cord-350019-4nlbu54e	51	3	]	]	-RRB-
cord-350019-4nlbu54e	51	4	[	[	-LRB-
cord-350019-4nlbu54e	51	5	28	28	CD
cord-350019-4nlbu54e	51	6	]	]	-RRB-
cord-350019-4nlbu54e	51	7	[	[	-LRB-
cord-350019-4nlbu54e	51	8	29	29	CD
cord-350019-4nlbu54e	51	9	]	]	-RRB-
cord-350019-4nlbu54e	51	10	[	[	-LRB-
cord-350019-4nlbu54e	51	11	30	30	CD
cord-350019-4nlbu54e	51	12	]	]	-RRB-
cord-350019-4nlbu54e	51	13	.	.	.
cord-350019-4nlbu54e	52	1	We	-PRON-	PRP
cord-350019-4nlbu54e	52	2	believe	believe	VBP
cord-350019-4nlbu54e	52	3	that	that	IN
cord-350019-4nlbu54e	52	4	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	52	5	play	play	VB
cord-350019-4nlbu54e	52	6	regulatory	regulatory	JJ
cord-350019-4nlbu54e	52	7	roles	role	NNS
cord-350019-4nlbu54e	52	8	in	in	IN
cord-350019-4nlbu54e	52	9	many	many	JJ
cord-350019-4nlbu54e	52	10	biological	biological	JJ
cord-350019-4nlbu54e	52	11	processes	process	NNS
cord-350019-4nlbu54e	52	12	and	and	CC
cord-350019-4nlbu54e	52	13	diseases	disease	NNS
cord-350019-4nlbu54e	52	14	.	.	.
cord-350019-4nlbu54e	53	1	Therefore	therefore	RB
cord-350019-4nlbu54e	53	2	,	,	,
cord-350019-4nlbu54e	53	3	no	no	RB
cord-350019-4nlbu54e	53	4	matter	matter	RB
cord-350019-4nlbu54e	53	5	what	what	WP
cord-350019-4nlbu54e	53	6	your	-PRON-	PRP$
cord-350019-4nlbu54e	53	7	research	research	NN
cord-350019-4nlbu54e	53	8	area	area	NN
cord-350019-4nlbu54e	53	9	is	be	VBZ
cord-350019-4nlbu54e	53	10	,	,	,
cord-350019-4nlbu54e	53	11	there	there	EX
cord-350019-4nlbu54e	53	12	is	be	VBZ
cord-350019-4nlbu54e	53	13	a	a	DT
cord-350019-4nlbu54e	53	14	rich	rich	JJ
cord-350019-4nlbu54e	53	15	source	source	NN
cord-350019-4nlbu54e	53	16	of	of	IN
cord-350019-4nlbu54e	53	17	information	information	NN
cord-350019-4nlbu54e	53	18	to	to	TO
cord-350019-4nlbu54e	53	19	be	be	VB
cord-350019-4nlbu54e	53	20	obtained	obtain	VBN
cord-350019-4nlbu54e	53	21	from	from	IN
cord-350019-4nlbu54e	53	22	the	the	DT
cord-350019-4nlbu54e	53	23	study	study	NN
cord-350019-4nlbu54e	53	24	of	of	IN
cord-350019-4nlbu54e	53	25	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	53	26	in	in	IN
cord-350019-4nlbu54e	53	27	your	-PRON-	PRP$
cord-350019-4nlbu54e	53	28	field	field	NN
cord-350019-4nlbu54e	53	29	of	of	IN
cord-350019-4nlbu54e	53	30	interest	interest	NN
cord-350019-4nlbu54e	53	31	.	.	.
cord-350019-4nlbu54e	54	1	The	the	DT
cord-350019-4nlbu54e	54	2	bulk	bulk	NN
cord-350019-4nlbu54e	54	3	of	of	IN
cord-350019-4nlbu54e	54	4	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	54	5	studies	study	NNS
cord-350019-4nlbu54e	54	6	to	to	IN
cord-350019-4nlbu54e	54	7	date	date	NN
cord-350019-4nlbu54e	54	8	have	have	VBP
cord-350019-4nlbu54e	54	9	focused	focus	VBN
cord-350019-4nlbu54e	54	10	on	on	IN
cord-350019-4nlbu54e	54	11	the	the	DT
cord-350019-4nlbu54e	54	12	cancer	cancer	NN
cord-350019-4nlbu54e	54	13	field	field	NN
cord-350019-4nlbu54e	54	14	[	[	-LRB-
cord-350019-4nlbu54e	54	15	31	31	CD
cord-350019-4nlbu54e	54	16	]	]	-RRB-
cord-350019-4nlbu54e	54	17	[	[	-LRB-
cord-350019-4nlbu54e	54	18	32	32	CD
cord-350019-4nlbu54e	54	19	]	]	-RRB-
cord-350019-4nlbu54e	54	20	[	[	-LRB-
cord-350019-4nlbu54e	54	21	33	33	CD
cord-350019-4nlbu54e	54	22	]	]	-RRB-
cord-350019-4nlbu54e	54	23	.	.	.
cord-350019-4nlbu54e	55	1	Meanwhile	meanwhile	RB
cord-350019-4nlbu54e	55	2	,	,	,
cord-350019-4nlbu54e	55	3	studies	study	NNS
cord-350019-4nlbu54e	55	4	of	of	IN
cord-350019-4nlbu54e	55	5	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	55	6	in	in	IN
cord-350019-4nlbu54e	55	7	the	the	DT
cord-350019-4nlbu54e	55	8	context	context	NN
cord-350019-4nlbu54e	55	9	of	of	IN
cord-350019-4nlbu54e	55	10	innate	innate	JJ
cord-350019-4nlbu54e	55	11	immunity	immunity	NN
cord-350019-4nlbu54e	55	12	have	have	VBP
cord-350019-4nlbu54e	55	13	lagged	lag	VBN
cord-350019-4nlbu54e	55	14	,	,	,
cord-350019-4nlbu54e	55	15	making	make	VBG
cord-350019-4nlbu54e	55	16	up	up	RP
cord-350019-4nlbu54e	55	17	only~4	only~4	NNP
cord-350019-4nlbu54e	55	18	%	%	NN
cord-350019-4nlbu54e	55	19	of	of	IN
cord-350019-4nlbu54e	55	20	all	all	DT
cord-350019-4nlbu54e	55	21	lncRNA	lncrna	NN
cord-350019-4nlbu54e	55	22	papers	paper	NNS
cord-350019-4nlbu54e	55	23	to	to	IN
cord-350019-4nlbu54e	55	24	date	date	NN
cord-350019-4nlbu54e	55	25	(	(	-LRB-
cord-350019-4nlbu54e	55	26	Fig	fig	NN
cord-350019-4nlbu54e	55	27	.	.	.
cord-350019-4nlbu54e	55	28	1	1	CD
cord-350019-4nlbu54e	55	29	)	)	-RRB-
cord-350019-4nlbu54e	55	30	.	.	.
cord-350019-4nlbu54e	56	1	The	the	DT
cord-350019-4nlbu54e	56	2	innate	innate	JJ
cord-350019-4nlbu54e	56	3	immune	immune	JJ
cord-350019-4nlbu54e	56	4	system	system	NN
cord-350019-4nlbu54e	56	5	provides	provide	VBZ
cord-350019-4nlbu54e	56	6	one	one	CD
cord-350019-4nlbu54e	56	7	of	of	IN
cord-350019-4nlbu54e	56	8	the	the	DT
cord-350019-4nlbu54e	56	9	first	first	JJ
cord-350019-4nlbu54e	56	10	lines	line	NNS
cord-350019-4nlbu54e	56	11	of	of	IN
cord-350019-4nlbu54e	56	12	defense	defense	NN
cord-350019-4nlbu54e	56	13	against	against	IN
cord-350019-4nlbu54e	56	14	infection	infection	NN
cord-350019-4nlbu54e	56	15	through	through	IN
cord-350019-4nlbu54e	56	16	the	the	DT
cord-350019-4nlbu54e	56	17	induction	induction	NN
cord-350019-4nlbu54e	56	18	of	of	IN
cord-350019-4nlbu54e	56	19	inflammation	inflammation	NN
cord-350019-4nlbu54e	56	20	[	[	-LRB-
cord-350019-4nlbu54e	56	21	34	34	CD
cord-350019-4nlbu54e	56	22	,	,	,
cord-350019-4nlbu54e	56	23	35	35	CD
cord-350019-4nlbu54e	56	24	]	]	-RRB-
cord-350019-4nlbu54e	56	25	.	.	.
cord-350019-4nlbu54e	57	1	The	the	DT
cord-350019-4nlbu54e	57	2	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	57	3	response	response	NN
cord-350019-4nlbu54e	57	4	of	of	IN
cord-350019-4nlbu54e	57	5	murine	murine	JJ
cord-350019-4nlbu54e	57	6	macrophages	macrophage	NNS
cord-350019-4nlbu54e	57	7	offers	offer	VBZ
cord-350019-4nlbu54e	57	8	a	a	DT
cord-350019-4nlbu54e	57	9	powerful	powerful	JJ
cord-350019-4nlbu54e	57	10	system	system	NN
cord-350019-4nlbu54e	57	11	for	for	IN
cord-350019-4nlbu54e	57	12	applying	apply	VBG
cord-350019-4nlbu54e	57	13	genomic	genomic	JJ
cord-350019-4nlbu54e	57	14	approaches	approach	NNS
cord-350019-4nlbu54e	57	15	for	for	IN
cord-350019-4nlbu54e	57	16	studying	study	VBG
cord-350019-4nlbu54e	57	17	novel	novel	NN
cord-350019-4nlbu54e	58	1	lncRNAs	lncrnas	RB
cord-350019-4nlbu54e	58	2	within	within	IN
cord-350019-4nlbu54e	58	3	the	the	DT
cord-350019-4nlbu54e	58	4	framework	framework	NN
cord-350019-4nlbu54e	58	5	of	of	IN
cord-350019-4nlbu54e	58	6	a	a	DT
cord-350019-4nlbu54e	58	7	pathway	pathway	NN
cord-350019-4nlbu54e	58	8	that	that	WDT
cord-350019-4nlbu54e	58	9	has	have	VBZ
cord-350019-4nlbu54e	58	10	been	be	VBN
cord-350019-4nlbu54e	58	11	studied	study	VBN
cord-350019-4nlbu54e	58	12	for	for	IN
cord-350019-4nlbu54e	58	13	decades	decade	NNS
cord-350019-4nlbu54e	58	14	.	.	.
cord-350019-4nlbu54e	59	1	Macrophages	macrophage	NNS
cord-350019-4nlbu54e	59	2	are	be	VBP
cord-350019-4nlbu54e	59	3	important	important	JJ
cord-350019-4nlbu54e	59	4	mediators	mediator	NNS
cord-350019-4nlbu54e	59	5	of	of	IN
cord-350019-4nlbu54e	59	6	inflammation	inflammation	NN
cord-350019-4nlbu54e	59	7	and	and	CC
cord-350019-4nlbu54e	59	8	initiate	initiate	VB
cord-350019-4nlbu54e	59	9	this	this	DT
cord-350019-4nlbu54e	59	10	response	response	NN
cord-350019-4nlbu54e	59	11	through	through	IN
cord-350019-4nlbu54e	59	12	recognition	recognition	NN
cord-350019-4nlbu54e	59	13	of	of	IN
cord-350019-4nlbu54e	59	14	specific	specific	JJ
cord-350019-4nlbu54e	59	15	pathogen	pathogen	NN
cord-350019-4nlbu54e	59	16	-	-	HYPH
cord-350019-4nlbu54e	59	17	associated	associate	VBN
cord-350019-4nlbu54e	59	18	molecular	molecular	JJ
cord-350019-4nlbu54e	59	19	patterns	pattern	NNS
cord-350019-4nlbu54e	59	20	(	(	-LRB-
cord-350019-4nlbu54e	59	21	PAMPs	pamp	NNS
cord-350019-4nlbu54e	59	22	)	)	-RRB-
cord-350019-4nlbu54e	59	23	through	through	IN
cord-350019-4nlbu54e	59	24	their	-PRON-	PRP$
cord-350019-4nlbu54e	59	25	germline	germline	NN
cord-350019-4nlbu54e	59	26	-	-	HYPH
cord-350019-4nlbu54e	59	27	encoded	encode	VBN
cord-350019-4nlbu54e	59	28	pattern	pattern	NN
cord-350019-4nlbu54e	59	29	recognition	recognition	NN
cord-350019-4nlbu54e	59	30	receptors	receptor	NNS
cord-350019-4nlbu54e	59	31	(	(	-LRB-
cord-350019-4nlbu54e	59	32	PRRs	PRRs	NNP
cord-350019-4nlbu54e	59	33	)	)	-RRB-
cord-350019-4nlbu54e	59	34	.	.	.
cord-350019-4nlbu54e	60	1	These	these	DT
cord-350019-4nlbu54e	60	2	receptors	receptor	NNS
cord-350019-4nlbu54e	60	3	couple	couple	VBP
cord-350019-4nlbu54e	60	4	pathogensensing	pathogensense	VBG
cord-350019-4nlbu54e	60	5	to	to	IN
cord-350019-4nlbu54e	60	6	activation	activation	NN
cord-350019-4nlbu54e	60	7	of	of	IN
cord-350019-4nlbu54e	60	8	downstream	downstream	JJ
cord-350019-4nlbu54e	60	9	signaling	signaling	NN
cord-350019-4nlbu54e	60	10	cascades	cascade	NNS
cord-350019-4nlbu54e	60	11	resulting	result	VBG
cord-350019-4nlbu54e	60	12	in	in	IN
cord-350019-4nlbu54e	60	13	activation	activation	NN
cord-350019-4nlbu54e	60	14	of	of	IN
cord-350019-4nlbu54e	60	15	numerous	numerous	JJ
cord-350019-4nlbu54e	60	16	transcription	transcription	NN
cord-350019-4nlbu54e	60	17	factors	factor	NNS
cord-350019-4nlbu54e	60	18	,	,	,
cord-350019-4nlbu54e	60	19	including	include	VBG
cord-350019-4nlbu54e	60	20	NF	nf	NN
cord-350019-4nlbu54e	60	21	-	-	HYPH
cord-350019-4nlbu54e	60	22	kappaB	kappaB	NNP
cord-350019-4nlbu54e	60	23	(	(	-LRB-
cord-350019-4nlbu54e	60	24	NF	nf	NN
cord-350019-4nlbu54e	60	25	-	-	HYPH
cord-350019-4nlbu54e	60	26	κB	κB	NNP
cord-350019-4nlbu54e	60	27	)	)	-RRB-
cord-350019-4nlbu54e	60	28	and	and	CC
cord-350019-4nlbu54e	60	29	interferon	interferon	NN
cord-350019-4nlbu54e	60	30	regulatory	regulatory	JJ
cord-350019-4nlbu54e	60	31	factors	factor	NNS
cord-350019-4nlbu54e	60	32	(	(	-LRB-
cord-350019-4nlbu54e	60	33	IRFs	IRFs	NNP
cord-350019-4nlbu54e	60	34	)	)	-RRB-
cord-350019-4nlbu54e	60	35	that	that	WDT
cord-350019-4nlbu54e	60	36	can	can	MD
cord-350019-4nlbu54e	60	37	act	act	VB
cord-350019-4nlbu54e	60	38	in	in	IN
cord-350019-4nlbu54e	60	39	combination	combination	NN
cord-350019-4nlbu54e	60	40	to	to	IN
cord-350019-4nlbu54e	60	41	both	both	CC
cord-350019-4nlbu54e	60	42	positively	positively	RB
cord-350019-4nlbu54e	60	43	and	and	CC
cord-350019-4nlbu54e	60	44	negatively	negatively	RB
cord-350019-4nlbu54e	60	45	regulate	regulate	VB
cord-350019-4nlbu54e	60	46	the	the	DT
cord-350019-4nlbu54e	60	47	expression	expression	NN
cord-350019-4nlbu54e	60	48	of	of	IN
cord-350019-4nlbu54e	60	49	thousands	thousand	NNS
cord-350019-4nlbu54e	60	50	of	of	IN
cord-350019-4nlbu54e	60	51	genes	gene	NNS
cord-350019-4nlbu54e	60	52	[	[	-LRB-
cord-350019-4nlbu54e	60	53	36	36	CD
cord-350019-4nlbu54e	60	54	,	,	,
cord-350019-4nlbu54e	60	55	37	37	CD
cord-350019-4nlbu54e	60	56	]	]	-RRB-
cord-350019-4nlbu54e	60	57	.	.	.
cord-350019-4nlbu54e	61	1	There	there	EX
cord-350019-4nlbu54e	61	2	are	be	VBP
cord-350019-4nlbu54e	61	3	10	10	CD
cord-350019-4nlbu54e	61	4	different	different	JJ
cord-350019-4nlbu54e	61	5	TLR	TLR	NNP
cord-350019-4nlbu54e	61	6	genes	gene	NNS
cord-350019-4nlbu54e	61	7	in	in	IN
cord-350019-4nlbu54e	61	8	the	the	DT
cord-350019-4nlbu54e	61	9	human	human	JJ
cord-350019-4nlbu54e	61	10	genome	genome	NN
cord-350019-4nlbu54e	61	11	and	and	CC
cord-350019-4nlbu54e	61	12	13	13	CD
cord-350019-4nlbu54e	61	13	TLR	TLR	NNP
cord-350019-4nlbu54e	61	14	genes	gene	NNS
cord-350019-4nlbu54e	61	15	in	in	IN
cord-350019-4nlbu54e	61	16	mice	mouse	NNS
cord-350019-4nlbu54e	61	17	[	[	-LRB-
cord-350019-4nlbu54e	61	18	38	38	CD
cord-350019-4nlbu54e	61	19	]	]	-RRB-
cord-350019-4nlbu54e	61	20	[	[	-LRB-
cord-350019-4nlbu54e	61	21	39	39	CD
cord-350019-4nlbu54e	61	22	]	]	-RRB-
cord-350019-4nlbu54e	61	23	[	[	-LRB-
cord-350019-4nlbu54e	61	24	40	40	CD
cord-350019-4nlbu54e	61	25	]	]	-RRB-
cord-350019-4nlbu54e	61	26	,	,	,
cord-350019-4nlbu54e	61	27	each	each	DT
cord-350019-4nlbu54e	61	28	binding	bind	VBG
cord-350019-4nlbu54e	61	29	a	a	DT
cord-350019-4nlbu54e	61	30	different	different	JJ
cord-350019-4nlbu54e	61	31	PAMP	PAMP	NNS
cord-350019-4nlbu54e	61	32	[	[	-LRB-
cord-350019-4nlbu54e	61	33	41	41	CD
cord-350019-4nlbu54e	61	34	]	]	-RRB-
cord-350019-4nlbu54e	61	35	.	.	.
cord-350019-4nlbu54e	62	1	Using	use	VBG
cord-350019-4nlbu54e	62	2	this	this	DT
cord-350019-4nlbu54e	62	3	extensively	extensively	RB
cord-350019-4nlbu54e	62	4	studied	study	VBN
cord-350019-4nlbu54e	62	5	biological	biological	JJ
cord-350019-4nlbu54e	62	6	system	system	NN
cord-350019-4nlbu54e	62	7	,	,	,
cord-350019-4nlbu54e	62	8	we	-PRON-	PRP
cord-350019-4nlbu54e	62	9	identified	identify	VBD
cord-350019-4nlbu54e	62	10	the	the	DT
cord-350019-4nlbu54e	62	11	first	first	JJ
cord-350019-4nlbu54e	62	12	example	example	NN
cord-350019-4nlbu54e	62	13	of	of	IN
cord-350019-4nlbu54e	62	14	a	a	DT
cord-350019-4nlbu54e	62	15	TLR	TLR	NNP
cord-350019-4nlbu54e	62	16	-	-	HYPH
cord-350019-4nlbu54e	62	17	stimulated	stimulate	VBN
cord-350019-4nlbu54e	62	18	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	62	19	,	,	,
cord-350019-4nlbu54e	62	20	lincRNA	lincRNA	VBG
cord-350019-4nlbu54e	62	21	-	-	HYPH
cord-350019-4nlbu54e	62	22	Cox2	Cox2	NNP
cord-350019-4nlbu54e	62	23	,	,	,
cord-350019-4nlbu54e	62	24	which	which	WDT
cord-350019-4nlbu54e	62	25	was	be	VBD
cord-350019-4nlbu54e	62	26	capable	capable	JJ
cord-350019-4nlbu54e	62	27	of	of	IN
cord-350019-4nlbu54e	62	28	positively	positively	RB
cord-350019-4nlbu54e	62	29	and	and	CC
cord-350019-4nlbu54e	62	30	negatively	negatively	RB
cord-350019-4nlbu54e	62	31	regulating	regulate	VBG
cord-350019-4nlbu54e	62	32	distinct	distinct	JJ
cord-350019-4nlbu54e	62	33	types	type	NNS
cord-350019-4nlbu54e	62	34	of	of	IN
cord-350019-4nlbu54e	62	35	innate	innate	JJ
cord-350019-4nlbu54e	62	36	immune	immune	JJ
cord-350019-4nlbu54e	62	37	genes	gene	NNS
cord-350019-4nlbu54e	62	38	[	[	-LRB-
cord-350019-4nlbu54e	62	39	42	42	CD
cord-350019-4nlbu54e	62	40	]	]	-RRB-
cord-350019-4nlbu54e	62	41	[	[	-LRB-
cord-350019-4nlbu54e	62	42	43	43	CD
cord-350019-4nlbu54e	62	43	]	]	-RRB-
cord-350019-4nlbu54e	62	44	[	[	-LRB-
cord-350019-4nlbu54e	62	45	44	44	CD
cord-350019-4nlbu54e	62	46	]	]	-RRB-
cord-350019-4nlbu54e	62	47	[	[	-LRB-
cord-350019-4nlbu54e	62	48	45	45	CD
cord-350019-4nlbu54e	62	49	]	]	-RRB-
cord-350019-4nlbu54e	62	50	[	[	-LRB-
cord-350019-4nlbu54e	62	51	46	46	CD
cord-350019-4nlbu54e	62	52	]	]	-RRB-
cord-350019-4nlbu54e	62	53	.	.	.
cord-350019-4nlbu54e	63	1	Knockdown	knockdown	NN
cord-350019-4nlbu54e	63	2	of	of	IN
cord-350019-4nlbu54e	63	3	lincRNA	lincrna	RB
cord-350019-4nlbu54e	63	4	-	-	HYPH
cord-350019-4nlbu54e	63	5	Cox2	Cox2	NNP
cord-350019-4nlbu54e	63	6	resulted	result	VBD
cord-350019-4nlbu54e	63	7	in	in	IN
cord-350019-4nlbu54e	63	8	impaired	impaired	JJ
cord-350019-4nlbu54e	63	9	production	production	NN
cord-350019-4nlbu54e	63	10	of	of	IN
cord-350019-4nlbu54e	63	11	proinflammatory	proinflammatory	JJ
cord-350019-4nlbu54e	63	12	genes	gene	NNS
cord-350019-4nlbu54e	63	13	(	(	-LRB-
cord-350019-4nlbu54e	63	14	i.e.	i.e.	FW
cord-350019-4nlbu54e	63	15	,	,	,
cord-350019-4nlbu54e	63	16	IL-6	IL-6	NNP
cord-350019-4nlbu54e	63	17	)	)	-RRB-
cord-350019-4nlbu54e	63	18	,	,	,
cord-350019-4nlbu54e	63	19	while	while	IN
cord-350019-4nlbu54e	63	20	IFNrelated	ifnrelate	VBN
cord-350019-4nlbu54e	63	21	genes	gene	NNS
cord-350019-4nlbu54e	63	22	were	be	VBD
cord-350019-4nlbu54e	63	23	hyperactivated	hyperactivate	VBN
cord-350019-4nlbu54e	63	24	in	in	IN
cord-350019-4nlbu54e	63	25	the	the	DT
cord-350019-4nlbu54e	63	26	absence	absence	NN
cord-350019-4nlbu54e	63	27	of	of	IN
cord-350019-4nlbu54e	63	28	lincRNA	lincrna	RB
cord-350019-4nlbu54e	63	29	-	-	HYPH
cord-350019-4nlbu54e	63	30	Cox2	Cox2	NNP
cord-350019-4nlbu54e	63	31	[	[	-LRB-
cord-350019-4nlbu54e	63	32	42	42	CD
cord-350019-4nlbu54e	63	33	]	]	-RRB-
cord-350019-4nlbu54e	64	1	[	[	-LRB-
cord-350019-4nlbu54e	64	2	43	43	CD
cord-350019-4nlbu54e	64	3	]	]	-RRB-
cord-350019-4nlbu54e	64	4	[	[	-LRB-
cord-350019-4nlbu54e	64	5	44	44	CD
cord-350019-4nlbu54e	64	6	]	]	-RRB-
cord-350019-4nlbu54e	65	1	[	[	-LRB-
cord-350019-4nlbu54e	65	2	45	45	CD
cord-350019-4nlbu54e	65	3	]	]	-RRB-
cord-350019-4nlbu54e	65	4	[	[	-LRB-
cord-350019-4nlbu54e	65	5	46	46	CD
cord-350019-4nlbu54e	65	6	]	]	-RRB-
cord-350019-4nlbu54e	65	7	.	.	.
cord-350019-4nlbu54e	66	1	Numerous	numerous	JJ
cord-350019-4nlbu54e	66	2	other	other	JJ
cord-350019-4nlbu54e	66	3	studies	study	NNS
cord-350019-4nlbu54e	66	4	have	have	VBP
cord-350019-4nlbu54e	66	5	made	make	VBN
cord-350019-4nlbu54e	66	6	use	use	NN
cord-350019-4nlbu54e	66	7	of	of	IN
cord-350019-4nlbu54e	66	8	the	the	DT
cord-350019-4nlbu54e	66	9	TLR	TLR	NNP
cord-350019-4nlbu54e	66	10	-	-	HYPH
cord-350019-4nlbu54e	66	11	signaling	signal	VBG
cord-350019-4nlbu54e	66	12	biological	biological	JJ
cord-350019-4nlbu54e	66	13	system	system	NN
cord-350019-4nlbu54e	66	14	,	,	,
cord-350019-4nlbu54e	66	15	uncovering	uncover	VBG
cord-350019-4nlbu54e	66	16	and	and	CC
cord-350019-4nlbu54e	66	17	characterizing	characterize	VBG
cord-350019-4nlbu54e	66	18	dozens	dozen	NNS
cord-350019-4nlbu54e	66	19	of	of	IN
cord-350019-4nlbu54e	66	20	novel	novel	NN
cord-350019-4nlbu54e	66	21	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	66	22	that	that	WDT
cord-350019-4nlbu54e	66	23	act	act	VBP
cord-350019-4nlbu54e	66	24	in	in	IN
cord-350019-4nlbu54e	66	25	a	a	DT
cord-350019-4nlbu54e	66	26	wide	wide	JJ
cord-350019-4nlbu54e	66	27	range	range	NN
cord-350019-4nlbu54e	66	28	of	of	IN
cord-350019-4nlbu54e	66	29	mechanisms	mechanism	NNS
cord-350019-4nlbu54e	66	30	to	to	IN
cord-350019-4nlbu54e	66	31	either	either	CC
cord-350019-4nlbu54e	66	32	positively	positively	RB
cord-350019-4nlbu54e	66	33	or	or	CC
cord-350019-4nlbu54e	66	34	negatively	negatively	RB
cord-350019-4nlbu54e	66	35	regulate	regulate	VB
cord-350019-4nlbu54e	66	36	this	this	DT
cord-350019-4nlbu54e	66	37	pathway	pathway	NN
cord-350019-4nlbu54e	66	38	as	as	IN
cord-350019-4nlbu54e	66	39	reviewed	review	VBN
cord-350019-4nlbu54e	66	40	in	in	IN
cord-350019-4nlbu54e	66	41	Carpenter	Carpenter	NNP
cord-350019-4nlbu54e	66	42	et	et	NNP
cord-350019-4nlbu54e	66	43	al	al	NNP
cord-350019-4nlbu54e	66	44	.	.	.
cord-350019-4nlbu54e	67	1	and	and	CC
cord-350019-4nlbu54e	67	2	Hadjicharalambous	Hadjicharalambous	NNP
cord-350019-4nlbu54e	67	3	et	et	NNP
cord-350019-4nlbu54e	67	4	al	al	NNP
cord-350019-4nlbu54e	67	5	.	.	.
cord-350019-4nlbu54e	68	1	[	[	-LRB-
cord-350019-4nlbu54e	68	2	47	47	CD
cord-350019-4nlbu54e	68	3	,	,	,
cord-350019-4nlbu54e	68	4	48	48	CD
cord-350019-4nlbu54e	68	5	]	]	-RRB-
cord-350019-4nlbu54e	68	6	.	.	.
cord-350019-4nlbu54e	69	1	As	as	IN
cord-350019-4nlbu54e	69	2	mentioned	mention	VBN
cord-350019-4nlbu54e	69	3	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	69	4	are	be	VBP
cord-350019-4nlbu54e	69	5	categorized	categorize	VBN
cord-350019-4nlbu54e	69	6	into	into	IN
cord-350019-4nlbu54e	69	7	five	five	CD
cord-350019-4nlbu54e	69	8	main	main	JJ
cord-350019-4nlbu54e	69	9	classes	class	NNS
cord-350019-4nlbu54e	69	10	of	of	IN
cord-350019-4nlbu54e	69	11	long	long	JJ
cord-350019-4nlbu54e	69	12	noncoding	noncoding	JJ
cord-350019-4nlbu54e	69	13	RNAs	rna	NNS
cord-350019-4nlbu54e	69	14	based	base	VBN
cord-350019-4nlbu54e	69	15	on	on	IN
cord-350019-4nlbu54e	69	16	their	-PRON-	PRP$
cord-350019-4nlbu54e	69	17	genomic	genomic	JJ
cord-350019-4nlbu54e	69	18	location	location	NN
cord-350019-4nlbu54e	69	19	:	:	:
cord-350019-4nlbu54e	69	20	antisense	antisense	NN
cord-350019-4nlbu54e	69	21	,	,	,
cord-350019-4nlbu54e	69	22	bidirectional	bidirectional	JJ
cord-350019-4nlbu54e	69	23	,	,	,
cord-350019-4nlbu54e	69	24	intronic	intronic	JJ
cord-350019-4nlbu54e	69	25	,	,	,
cord-350019-4nlbu54e	69	26	enhancer	enhancer	NN
cord-350019-4nlbu54e	69	27	-	-	HYPH
cord-350019-4nlbu54e	69	28	associated	associate	VBN
cord-350019-4nlbu54e	69	29	,	,	,
cord-350019-4nlbu54e	69	30	and	and	CC
cord-350019-4nlbu54e	69	31	intergenic	intergenic	JJ
cord-350019-4nlbu54e	69	32	.	.	.
cord-350019-4nlbu54e	70	1	Intergenic	intergenic	JJ
cord-350019-4nlbu54e	70	2	and	and	CC
cord-350019-4nlbu54e	70	3	enhancer	enhancer	NN
cord-350019-4nlbu54e	70	4	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	70	5	contain	contain	VBP
cord-350019-4nlbu54e	70	6	their	-PRON-	PRP$
cord-350019-4nlbu54e	70	7	own	own	JJ
cord-350019-4nlbu54e	70	8	promoters	promoter	NNS
cord-350019-4nlbu54e	70	9	and	and	CC
cord-350019-4nlbu54e	70	10	are	be	VBP
cord-350019-4nlbu54e	70	11	distinct	distinct	JJ
cord-350019-4nlbu54e	70	12	from	from	IN
cord-350019-4nlbu54e	70	13	protein	protein	NN
cord-350019-4nlbu54e	70	14	-	-	HYPH
cord-350019-4nlbu54e	70	15	coding	code	VBG
cord-350019-4nlbu54e	70	16	genes	gene	NNS
cord-350019-4nlbu54e	70	17	.	.	.
cord-350019-4nlbu54e	71	1	Bidirectional	bidirectional	JJ
cord-350019-4nlbu54e	71	2	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	71	3	share	share	VB
cord-350019-4nlbu54e	71	4	a	a	DT
cord-350019-4nlbu54e	71	5	promoter	promoter	NN
cord-350019-4nlbu54e	71	6	and	and	CC
cord-350019-4nlbu54e	71	7	are	be	VBP
cord-350019-4nlbu54e	71	8	transcribed	transcribe	VBN
cord-350019-4nlbu54e	71	9	from	from	IN
cord-350019-4nlbu54e	71	10	the	the	DT
cord-350019-4nlbu54e	71	11	opposite	opposite	JJ
cord-350019-4nlbu54e	71	12	strand	strand	NN
cord-350019-4nlbu54e	71	13	of	of	IN
cord-350019-4nlbu54e	71	14	a	a	DT
cord-350019-4nlbu54e	71	15	protein	protein	NN
cord-350019-4nlbu54e	71	16	-	-	HYPH
cord-350019-4nlbu54e	71	17	coding	code	VBG
cord-350019-4nlbu54e	71	18	gene	gene	NN
cord-350019-4nlbu54e	71	19	,	,	,
cord-350019-4nlbu54e	71	20	while	while	IN
cord-350019-4nlbu54e	71	21	intronic	intronic	JJ
cord-350019-4nlbu54e	71	22	lncRNAs	lncrnas	UH
cord-350019-4nlbu54e	71	23	are	be	VBP
cord-350019-4nlbu54e	71	24	transcribed	transcribe	VBN
cord-350019-4nlbu54e	71	25	within	within	IN
cord-350019-4nlbu54e	71	26	an	an	DT
cord-350019-4nlbu54e	71	27	intronic	intronic	JJ
cord-350019-4nlbu54e	71	28	region	region	NN
cord-350019-4nlbu54e	71	29	of	of	IN
cord-350019-4nlbu54e	71	30	a	a	DT
cord-350019-4nlbu54e	71	31	proteincoding	proteincode	VBG
cord-350019-4nlbu54e	71	32	gene	gene	NN
cord-350019-4nlbu54e	71	33	(	(	-LRB-
cord-350019-4nlbu54e	71	34	Fig	Fig	NNP
cord-350019-4nlbu54e	71	35	.	.	.
cord-350019-4nlbu54e	71	36	2A	2a	CD
cord-350019-4nlbu54e	71	37	)	)	-RRB-
cord-350019-4nlbu54e	71	38	[	[	-LRB-
cord-350019-4nlbu54e	71	39	49	49	CD
cord-350019-4nlbu54e	71	40	,	,	,
cord-350019-4nlbu54e	71	41	50	50	CD
cord-350019-4nlbu54e	71	42	]	]	-RRB-
cord-350019-4nlbu54e	71	43	.	.	.
cord-350019-4nlbu54e	72	1	The	the	DT
cord-350019-4nlbu54e	72	2	specific	specific	JJ
cord-350019-4nlbu54e	72	3	class	class	NN
cord-350019-4nlbu54e	72	4	of	of	IN
cord-350019-4nlbu54e	72	5	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	72	6	can	can	MD
cord-350019-4nlbu54e	72	7	often	often	RB
cord-350019-4nlbu54e	72	8	provide	provide	VB
cord-350019-4nlbu54e	72	9	significant	significant	JJ
cord-350019-4nlbu54e	72	10	insight	insight	NN
cord-350019-4nlbu54e	72	11	into	into	IN
cord-350019-4nlbu54e	72	12	how	how	WRB
cord-350019-4nlbu54e	72	13	it	-PRON-	PRP
cord-350019-4nlbu54e	72	14	may	may	MD
cord-350019-4nlbu54e	72	15	regulate	regulate	VB
cord-350019-4nlbu54e	72	16	gene	gene	NN
cord-350019-4nlbu54e	72	17	expression	expression	NN
cord-350019-4nlbu54e	72	18	.	.	.
cord-350019-4nlbu54e	73	1	For	for	IN
cord-350019-4nlbu54e	73	2	example	example	NN
cord-350019-4nlbu54e	73	3	,	,	,
cord-350019-4nlbu54e	73	4	lncRNAs	lncrnas	RB
cord-350019-4nlbu54e	73	5	antisense	antisense	XX
cord-350019-4nlbu54e	73	6	to	to	IN
cord-350019-4nlbu54e	73	7	a	a	DT
cord-350019-4nlbu54e	73	8	coding	code	VBG
cord-350019-4nlbu54e	73	9	gene	gene	NN
cord-350019-4nlbu54e	73	10	have	have	VBP
cord-350019-4nlbu54e	73	11	been	be	VBN
cord-350019-4nlbu54e	73	12	demonstrated	demonstrate	VBN
cord-350019-4nlbu54e	73	13	to	to	TO
cord-350019-4nlbu54e	73	14	be	be	VB
cord-350019-4nlbu54e	73	15	involved	involve	VBN
cord-350019-4nlbu54e	73	16	in	in	IN
cord-350019-4nlbu54e	73	17	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	73	18	interference	interference	NN
cord-350019-4nlbu54e	73	19	,	,	,
cord-350019-4nlbu54e	73	20	negatively	negatively	RB
cord-350019-4nlbu54e	73	21	affecting	affect	VBG
cord-350019-4nlbu54e	73	22	the	the	DT
cord-350019-4nlbu54e	73	23	expression	expression	NN
cord-350019-4nlbu54e	73	24	of	of	IN
cord-350019-4nlbu54e	73	25	their	-PRON-	PRP$
cord-350019-4nlbu54e	73	26	coding	code	VBG
cord-350019-4nlbu54e	73	27	gene	gene	NN
cord-350019-4nlbu54e	73	28	[	[	-LRB-
cord-350019-4nlbu54e	73	29	51	51	CD
cord-350019-4nlbu54e	73	30	]	]	-RRB-
cord-350019-4nlbu54e	73	31	.	.	.
cord-350019-4nlbu54e	74	1	While	while	IN
cord-350019-4nlbu54e	74	2	all	all	DT
cord-350019-4nlbu54e	74	3	categories	category	NNS
cord-350019-4nlbu54e	74	4	of	of	IN
cord-350019-4nlbu54e	74	5	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	74	6	will	will	MD
cord-350019-4nlbu54e	74	7	no	no	RB
cord-350019-4nlbu54e	74	8	doubt	doubt	RB
cord-350019-4nlbu54e	74	9	be	be	VB
cord-350019-4nlbu54e	74	10	important	important	JJ
cord-350019-4nlbu54e	74	11	in	in	IN
cord-350019-4nlbu54e	74	12	various	various	JJ
cord-350019-4nlbu54e	74	13	biological	biological	JJ
cord-350019-4nlbu54e	74	14	processes	process	NNS
cord-350019-4nlbu54e	74	15	,	,	,
cord-350019-4nlbu54e	74	16	the	the	DT
cord-350019-4nlbu54e	74	17	most	most	RBS
cord-350019-4nlbu54e	74	18	targetable	targetable	JJ
cord-350019-4nlbu54e	74	19	lncRNAs	lncRNAs	NNPS
cord-350019-4nlbu54e	74	20	are	be	VBP
cord-350019-4nlbu54e	74	21	intergenic	intergenic	JJ
cord-350019-4nlbu54e	74	22	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	74	23	.	.	.
cord-350019-4nlbu54e	75	1	A	a	DT
cord-350019-4nlbu54e	75	2	benefit	benefit	NN
cord-350019-4nlbu54e	75	3	to	to	IN
cord-350019-4nlbu54e	75	4	studying	study	VBG
cord-350019-4nlbu54e	75	5	an	an	DT
cord-350019-4nlbu54e	75	6	intergenic	intergenic	JJ
cord-350019-4nlbu54e	75	7	lncRNA	lncrna	NN
cord-350019-4nlbu54e	75	8	(	(	-LRB-
cord-350019-4nlbu54e	75	9	lincRNA	lincRNA	NNP
cord-350019-4nlbu54e	75	10	)	)	-RRB-
cord-350019-4nlbu54e	75	11	is	be	VBZ
cord-350019-4nlbu54e	75	12	the	the	DT
cord-350019-4nlbu54e	75	13	immense	immense	JJ
cord-350019-4nlbu54e	75	14	variety	variety	NN
cord-350019-4nlbu54e	75	15	of	of	IN
cord-350019-4nlbu54e	75	16	molecular	molecular	JJ
cord-350019-4nlbu54e	75	17	techniques	technique	NNS
cord-350019-4nlbu54e	75	18	that	that	WDT
cord-350019-4nlbu54e	75	19	would	would	MD
cord-350019-4nlbu54e	75	20	not	not	RB
cord-350019-4nlbu54e	75	21	apply	apply	VB
cord-350019-4nlbu54e	75	22	to	to	IN
cord-350019-4nlbu54e	75	23	other	other	JJ
cord-350019-4nlbu54e	75	24	types	type	NNS
cord-350019-4nlbu54e	75	25	of	of	IN
cord-350019-4nlbu54e	75	26	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	75	27	,	,	,
cord-350019-4nlbu54e	75	28	such	such	JJ
cord-350019-4nlbu54e	75	29	as	as	IN
cord-350019-4nlbu54e	75	30	antisense	antisense	NN
cord-350019-4nlbu54e	75	31	,	,	,
cord-350019-4nlbu54e	75	32	bidirectional	bidirectional	JJ
cord-350019-4nlbu54e	75	33	and	and	CC
cord-350019-4nlbu54e	75	34	intronic	intronic	JJ
cord-350019-4nlbu54e	75	35	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	75	36	,	,	,
cord-350019-4nlbu54e	75	37	which	which	WDT
cord-350019-4nlbu54e	75	38	often	often	RB
cord-350019-4nlbu54e	75	39	overlap	overlap	VBP
cord-350019-4nlbu54e	75	40	coding	code	VBG
cord-350019-4nlbu54e	75	41	genes	gene	NNS
cord-350019-4nlbu54e	75	42	and	and	CC
cord-350019-4nlbu54e	75	43	their	-PRON-	PRP$
cord-350019-4nlbu54e	75	44	targeting	targeting	NN
cord-350019-4nlbu54e	75	45	could	could	MD
cord-350019-4nlbu54e	75	46	lead	lead	VB
cord-350019-4nlbu54e	75	47	to	to	IN
cord-350019-4nlbu54e	75	48	possible	possible	JJ
cord-350019-4nlbu54e	75	49	unwanted	unwanted	JJ
cord-350019-4nlbu54e	75	50	interference	interference	NN
cord-350019-4nlbu54e	75	51	of	of	IN
cord-350019-4nlbu54e	75	52	that	that	DT
cord-350019-4nlbu54e	75	53	coding	code	VBG
cord-350019-4nlbu54e	75	54	gene	gene	NN
cord-350019-4nlbu54e	75	55	.	.	.
cord-350019-4nlbu54e	76	1	Numerous	numerous	JJ
cord-350019-4nlbu54e	76	2	studies	study	NNS
cord-350019-4nlbu54e	76	3	have	have	VBP
cord-350019-4nlbu54e	76	4	established	establish	VBN
cord-350019-4nlbu54e	76	5	that	that	IN
cord-350019-4nlbu54e	76	6	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	76	7	can	can	MD
cord-350019-4nlbu54e	76	8	regulate	regulate	VB
cord-350019-4nlbu54e	76	9	the	the	DT
cord-350019-4nlbu54e	76	10	expression	expression	NN
cord-350019-4nlbu54e	76	11	of	of	IN
cord-350019-4nlbu54e	76	12	their	-PRON-	PRP$
cord-350019-4nlbu54e	76	13	neighboring	neighboring	JJ
cord-350019-4nlbu54e	76	14	coding	coding	NN
cord-350019-4nlbu54e	76	15	genes	gene	NNS
cord-350019-4nlbu54e	76	16	(	(	-LRB-
cord-350019-4nlbu54e	76	17	cis	cis	NNP
cord-350019-4nlbu54e	76	18	regulation	regulation	NN
cord-350019-4nlbu54e	76	19	)	)	-RRB-
cord-350019-4nlbu54e	76	20	[	[	-LRB-
cord-350019-4nlbu54e	76	21	51	51	CD
cord-350019-4nlbu54e	76	22	]	]	-RRB-
cord-350019-4nlbu54e	76	23	.	.	.
cord-350019-4nlbu54e	77	1	A	a	DT
cord-350019-4nlbu54e	77	2	recent	recent	JJ
cord-350019-4nlbu54e	77	3	study	study	NN
cord-350019-4nlbu54e	77	4	by	by	IN
cord-350019-4nlbu54e	77	5	Engreitz	Engreitz	NNP
cord-350019-4nlbu54e	77	6	et	et	NNP
cord-350019-4nlbu54e	77	7	al	al	NNP
cord-350019-4nlbu54e	77	8	.	.	NNP
cord-350019-4nlbu54e	77	9	demonstrated	demonstrate	VBD
cord-350019-4nlbu54e	77	10	that	that	IN
cord-350019-4nlbu54e	77	11	a	a	DT
cord-350019-4nlbu54e	77	12	significant	significant	JJ
cord-350019-4nlbu54e	77	13	portion	portion	NN
cord-350019-4nlbu54e	77	14	of	of	IN
cord-350019-4nlbu54e	77	15	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	77	16	had	have	VBD
cord-350019-4nlbu54e	77	17	cis	cis	JJ
cord-350019-4nlbu54e	77	18	effects	effect	NNS
cord-350019-4nlbu54e	77	19	on	on	IN
cord-350019-4nlbu54e	77	20	their	-PRON-	PRP$
cord-350019-4nlbu54e	77	21	neighboring	neighboring	NN
cord-350019-4nlbu54e	77	22	genes	gene	NNS
cord-350019-4nlbu54e	77	23	[	[	-LRB-
cord-350019-4nlbu54e	77	24	52	52	CD
cord-350019-4nlbu54e	77	25	]	]	-RRB-
cord-350019-4nlbu54e	77	26	.	.	.
cord-350019-4nlbu54e	78	1	Interestingly	interestingly	RB
cord-350019-4nlbu54e	78	2	,	,	,
cord-350019-4nlbu54e	78	3	in	in	IN
cord-350019-4nlbu54e	78	4	most	most	JJS
cord-350019-4nlbu54e	78	5	cases	case	NNS
cord-350019-4nlbu54e	78	6	,	,	,
cord-350019-4nlbu54e	78	7	the	the	DT
cord-350019-4nlbu54e	78	8	cis	cis	NNP
cord-350019-4nlbu54e	78	9	effect	effect	NN
cord-350019-4nlbu54e	78	10	did	do	VBD
cord-350019-4nlbu54e	78	11	not	not	RB
cord-350019-4nlbu54e	78	12	require	require	VB
cord-350019-4nlbu54e	78	13	the	the	DT
cord-350019-4nlbu54e	78	14	production	production	NN
cord-350019-4nlbu54e	78	15	of	of	IN
cord-350019-4nlbu54e	78	16	the	the	DT
cord-350019-4nlbu54e	78	17	lncRNA	lncrna	NN
cord-350019-4nlbu54e	78	18	transcripts	transcript	NNS
cord-350019-4nlbu54e	78	19	themselves	-PRON-	PRP
cord-350019-4nlbu54e	78	20	,	,	,
cord-350019-4nlbu54e	78	21	but	but	CC
cord-350019-4nlbu54e	78	22	instead	instead	RB
cord-350019-4nlbu54e	78	23	required	require	VBD
cord-350019-4nlbu54e	78	24	the	the	DT
cord-350019-4nlbu54e	78	25	processes	process	NNS
cord-350019-4nlbu54e	78	26	associated	associate	VBN
cord-350019-4nlbu54e	78	27	with	with	IN
cord-350019-4nlbu54e	78	28	their	-PRON-	PRP$
cord-350019-4nlbu54e	78	29	production	production	NN
cord-350019-4nlbu54e	78	30	,	,	,
cord-350019-4nlbu54e	78	31	such	such	JJ
cord-350019-4nlbu54e	78	32	as	as	IN
cord-350019-4nlbu54e	78	33	transcription	transcription	NN
cord-350019-4nlbu54e	78	34	and	and	CC
cord-350019-4nlbu54e	78	35	splicing	splicing	NN
cord-350019-4nlbu54e	78	36	[	[	-LRB-
cord-350019-4nlbu54e	78	37	52	52	CD
cord-350019-4nlbu54e	78	38	]	]	-RRB-
cord-350019-4nlbu54e	78	39	.	.	.
cord-350019-4nlbu54e	79	1	There	there	EX
cord-350019-4nlbu54e	79	2	are	be	VBP
cord-350019-4nlbu54e	79	3	many	many	JJ
cord-350019-4nlbu54e	79	4	examples	example	NNS
cord-350019-4nlbu54e	79	5	of	of	IN
cord-350019-4nlbu54e	79	6	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	79	7	that	that	WDT
cord-350019-4nlbu54e	79	8	regulate	regulate	VBP
cord-350019-4nlbu54e	79	9	their	-PRON-	PRP$
cord-350019-4nlbu54e	79	10	neighboring	neighbor	VBG
cord-350019-4nlbu54e	79	11	coding	coding	NN
cord-350019-4nlbu54e	79	12	genes	gene	NNS
cord-350019-4nlbu54e	79	13	,	,	,
cord-350019-4nlbu54e	79	14	for	for	IN
cord-350019-4nlbu54e	79	15	example	example	NN
cord-350019-4nlbu54e	79	16	:	:	:
cord-350019-4nlbu54e	79	17	lnc	lnc	NNP
cord-350019-4nlbu54e	79	18	-	-	HYPH
cord-350019-4nlbu54e	79	19	MARCKS	MARCKS	NNP
cord-350019-4nlbu54e	79	20	,	,	,
cord-350019-4nlbu54e	79	21	lnc	lnc	NNP
cord-350019-4nlbu54e	79	22	-	-	HYPH
cord-350019-4nlbu54e	79	23	TNFAIP3	TNFAIP3	NNP
cord-350019-4nlbu54e	79	24	,	,	,
cord-350019-4nlbu54e	79	25	AS	AS	NNP
cord-350019-4nlbu54e	79	26	-	-	HYPH
cord-350019-4nlbu54e	79	27	IL1α	IL1α	NNP
cord-350019-4nlbu54e	79	28	,	,	,
cord-350019-4nlbu54e	79	29	lnc	lnc	NNP
cord-350019-4nlbu54e	79	30	-	-	HYPH
cord-350019-4nlbu54e	79	31	IL7R	IL7R	NNP
cord-350019-4nlbu54e	79	32	,	,	,
cord-350019-4nlbu54e	79	33	and	and	CC
cord-350019-4nlbu54e	79	34	IL-1β	il-1β	NN
cord-350019-4nlbu54e	79	35	-	-	HYPH
cord-350019-4nlbu54e	79	36	eRNA	erna	NN
cord-350019-4nlbu54e	79	37	[	[	-LRB-
cord-350019-4nlbu54e	79	38	52	52	CD
cord-350019-4nlbu54e	79	39	]	]	-RRB-
cord-350019-4nlbu54e	79	40	[	[	-LRB-
cord-350019-4nlbu54e	79	41	53	53	CD
cord-350019-4nlbu54e	79	42	]	]	-RRB-
cord-350019-4nlbu54e	79	43	[	[	-LRB-
cord-350019-4nlbu54e	79	44	54	54	CD
cord-350019-4nlbu54e	79	45	]	]	-RRB-
cord-350019-4nlbu54e	79	46	[	[	-LRB-
cord-350019-4nlbu54e	79	47	55	55	CD
cord-350019-4nlbu54e	79	48	]	]	-RRB-
cord-350019-4nlbu54e	79	49	[	[	-LRB-
cord-350019-4nlbu54e	79	50	56	56	CD
cord-350019-4nlbu54e	79	51	]	]	-RRB-
cord-350019-4nlbu54e	79	52	.	.	.
cord-350019-4nlbu54e	80	1	Recently	recently	RB
cord-350019-4nlbu54e	80	2	we	-PRON-	PRP
cord-350019-4nlbu54e	80	3	used	use	VBD
cord-350019-4nlbu54e	80	4	genetic	genetic	JJ
cord-350019-4nlbu54e	80	5	mouse	mouse	NN
cord-350019-4nlbu54e	80	6	models	model	NNS
cord-350019-4nlbu54e	80	7	to	to	TO
cord-350019-4nlbu54e	80	8	show	show	VB
cord-350019-4nlbu54e	80	9	that	that	IN
cord-350019-4nlbu54e	80	10	lincRNA	lincrna	RB
cord-350019-4nlbu54e	80	11	-	-	:
cord-350019-4nlbu54e	80	12	Cox2	Cox2	NNP
cord-350019-4nlbu54e	80	13	can	can	MD
cord-350019-4nlbu54e	80	14	function	function	VB
cord-350019-4nlbu54e	80	15	as	as	IN
cord-350019-4nlbu54e	80	16	an	an	DT
cord-350019-4nlbu54e	80	17	enhancer	enhancer	NN
cord-350019-4nlbu54e	80	18	RNA	RNA	NNP
cord-350019-4nlbu54e	80	19	in	in	IN
cord-350019-4nlbu54e	80	20	cis	cis	NNP
cord-350019-4nlbu54e	80	21	to	to	TO
cord-350019-4nlbu54e	80	22	regulate	regulate	VB
cord-350019-4nlbu54e	80	23	its	-PRON-	PRP$
cord-350019-4nlbu54e	80	24	neighboring	neighboring	NN
cord-350019-4nlbu54e	80	25	gene	gene	NN
cord-350019-4nlbu54e	80	26	Ptgs2	Ptgs2	NNS
cord-350019-4nlbu54e	80	27	[	[	-LRB-
cord-350019-4nlbu54e	80	28	46	46	CD
cord-350019-4nlbu54e	80	29	]	]	-RRB-
cord-350019-4nlbu54e	80	30	.	.	.
cord-350019-4nlbu54e	81	1	For	for	IN
cord-350019-4nlbu54e	81	2	these	these	DT
cord-350019-4nlbu54e	81	3	reasons	reason	NNS
cord-350019-4nlbu54e	81	4	,	,	,
cord-350019-4nlbu54e	81	5	one	one	CD
cord-350019-4nlbu54e	81	6	aspect	aspect	NN
cord-350019-4nlbu54e	81	7	to	to	TO
cord-350019-4nlbu54e	81	8	consider	consider	VB
cord-350019-4nlbu54e	81	9	when	when	WRB
cord-350019-4nlbu54e	81	10	selecting	select	VBG
cord-350019-4nlbu54e	81	11	a	a	DT
cord-350019-4nlbu54e	81	12	candidate	candidate	NN
cord-350019-4nlbu54e	81	13	,	,	,
cord-350019-4nlbu54e	81	14	no	no	RB
cord-350019-4nlbu54e	81	15	matter	matter	RB
cord-350019-4nlbu54e	81	16	the	the	DT
cord-350019-4nlbu54e	81	17	class	class	NN
cord-350019-4nlbu54e	81	18	,	,	,
cord-350019-4nlbu54e	81	19	is	be	VBZ
cord-350019-4nlbu54e	81	20	to	to	TO
cord-350019-4nlbu54e	81	21	investigate	investigate	VB
cord-350019-4nlbu54e	81	22	the	the	DT
cord-350019-4nlbu54e	81	23	effect	effect	NN
cord-350019-4nlbu54e	81	24	of	of	IN
cord-350019-4nlbu54e	81	25	the	the	DT
cord-350019-4nlbu54e	81	26	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	81	27	expression	expression	NN
cord-350019-4nlbu54e	81	28	on	on	IN
cord-350019-4nlbu54e	81	29	neighboring	neighbor	VBG
cord-350019-4nlbu54e	81	30	coding	coding	NN
cord-350019-4nlbu54e	81	31	genes	gene	NNS
cord-350019-4nlbu54e	81	32	.	.	.
cord-350019-4nlbu54e	82	1	This	this	DT
cord-350019-4nlbu54e	82	2	candidate	candidate	NN
cord-350019-4nlbu54e	82	3	selection	selection	NN
cord-350019-4nlbu54e	82	4	approach	approach	NN
cord-350019-4nlbu54e	82	5	is	be	VBZ
cord-350019-4nlbu54e	82	6	sometimes	sometimes	RB
cord-350019-4nlbu54e	82	7	referred	refer	VBN
cord-350019-4nlbu54e	82	8	to	to	IN
cord-350019-4nlbu54e	82	9	as	as	IN
cord-350019-4nlbu54e	82	10	"	"	``
cord-350019-4nlbu54e	82	11	guilt	guilt	NN
cord-350019-4nlbu54e	82	12	by	by	IN
cord-350019-4nlbu54e	82	13	association	association	NN
cord-350019-4nlbu54e	82	14	"	"	''
cord-350019-4nlbu54e	82	15	[	[	-LRB-
cord-350019-4nlbu54e	82	16	57	57	CD
cord-350019-4nlbu54e	82	17	,	,	,
cord-350019-4nlbu54e	82	18	58	58	CD
cord-350019-4nlbu54e	82	19	]	]	-RRB-
cord-350019-4nlbu54e	82	20	.	.	.
cord-350019-4nlbu54e	83	1	This	this	DT
cord-350019-4nlbu54e	83	2	bioinformatic	bioinformatic	JJ
cord-350019-4nlbu54e	83	3	approach	approach	NN
cord-350019-4nlbu54e	83	4	drives	drive	VBZ
cord-350019-4nlbu54e	83	5	an	an	DT
cord-350019-4nlbu54e	83	6	initial	initial	JJ
cord-350019-4nlbu54e	83	7	hypothesis	hypothesis	NN
cord-350019-4nlbu54e	83	8	that	that	IN
cord-350019-4nlbu54e	83	9	the	the	DT
cord-350019-4nlbu54e	83	10	lncRNA	lncrna	NN
cord-350019-4nlbu54e	83	11	could	could	MD
cord-350019-4nlbu54e	83	12	be	be	VB
cord-350019-4nlbu54e	83	13	involved	involve	VBN
cord-350019-4nlbu54e	83	14	in	in	IN
cord-350019-4nlbu54e	83	15	the	the	DT
cord-350019-4nlbu54e	83	16	similar	similar	JJ
cord-350019-4nlbu54e	83	17	biological	biological	JJ
cord-350019-4nlbu54e	83	18	pathway	pathway	NN
cord-350019-4nlbu54e	83	19	as	as	IN
cord-350019-4nlbu54e	83	20	their	-PRON-	PRP$
cord-350019-4nlbu54e	83	21	neighboring	neighbor	VBG
cord-350019-4nlbu54e	83	22	protein	protein	NN
cord-350019-4nlbu54e	83	23	-	-	HYPH
cord-350019-4nlbu54e	83	24	coding	code	VBG
cord-350019-4nlbu54e	83	25	gene	gene	NN
cord-350019-4nlbu54e	83	26	due	due	IN
cord-350019-4nlbu54e	83	27	to	to	IN
cord-350019-4nlbu54e	83	28	their	-PRON-	PRP$
cord-350019-4nlbu54e	83	29	co	co	NN
cord-350019-4nlbu54e	83	30	-	-	NN
cord-350019-4nlbu54e	83	31	expression	expression	NN
cord-350019-4nlbu54e	83	32	.	.	.
cord-350019-4nlbu54e	84	1	A	a	DT
cord-350019-4nlbu54e	84	2	large	large	JJ
cord-350019-4nlbu54e	84	3	number	number	NN
cord-350019-4nlbu54e	84	4	of	of	IN
cord-350019-4nlbu54e	84	5	studies	study	NNS
cord-350019-4nlbu54e	84	6	to	to	IN
cord-350019-4nlbu54e	84	7	date	date	NN
cord-350019-4nlbu54e	84	8	have	have	VBP
cord-350019-4nlbu54e	84	9	also	also	RB
cord-350019-4nlbu54e	84	10	shown	show	VBN
cord-350019-4nlbu54e	84	11	that	that	IN
cord-350019-4nlbu54e	84	12	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	84	13	can	can	MD
cord-350019-4nlbu54e	84	14	regulate	regulate	VB
cord-350019-4nlbu54e	84	15	gene	gene	NN
cord-350019-4nlbu54e	84	16	expression	expression	NN
cord-350019-4nlbu54e	84	17	on	on	IN
cord-350019-4nlbu54e	84	18	different	different	JJ
cord-350019-4nlbu54e	84	19	chromosomes	chromosome	NNS
cord-350019-4nlbu54e	84	20	(	(	-LRB-
cord-350019-4nlbu54e	84	21	trans	trans	NNP
cord-350019-4nlbu54e	84	22	regulation	regulation	NN
cord-350019-4nlbu54e	84	23	)	)	-RRB-
cord-350019-4nlbu54e	84	24	[	[	-LRB-
cord-350019-4nlbu54e	84	25	59	59	CD
cord-350019-4nlbu54e	84	26	]	]	-RRB-
cord-350019-4nlbu54e	84	27	(	(	-LRB-
cord-350019-4nlbu54e	84	28	Fig	Fig	NNP
cord-350019-4nlbu54e	84	29	.	.	.
cord-350019-4nlbu54e	84	30	2C	2C	NNP
cord-350019-4nlbu54e	84	31	)	)	-RRB-
cord-350019-4nlbu54e	84	32	.	.	.
cord-350019-4nlbu54e	85	1	The	the	DT
cord-350019-4nlbu54e	85	2	majority	majority	NN
cord-350019-4nlbu54e	85	3	of	of	IN
cord-350019-4nlbu54e	85	4	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	85	5	studied	study	VBN
cord-350019-4nlbu54e	85	6	in	in	IN
cord-350019-4nlbu54e	85	7	immunity	immunity	NN
cord-350019-4nlbu54e	85	8	were	be	VBD
cord-350019-4nlbu54e	85	9	initially	initially	RB
cord-350019-4nlbu54e	85	10	identified	identify	VBN
cord-350019-4nlbu54e	85	11	following	follow	VBG
cord-350019-4nlbu54e	85	12	RNA	rna	NN
cord-350019-4nlbu54e	85	13	-	-	HYPH
cord-350019-4nlbu54e	85	14	sequencing	sequencing	NN
cord-350019-4nlbu54e	85	15	to	to	TO
cord-350019-4nlbu54e	85	16	examine	examine	VB
cord-350019-4nlbu54e	85	17	their	-PRON-	PRP$
cord-350019-4nlbu54e	85	18	expression	expression	NN
cord-350019-4nlbu54e	85	19	profiles	profile	NNS
cord-350019-4nlbu54e	85	20	in	in	IN
cord-350019-4nlbu54e	85	21	specific	specific	JJ
cord-350019-4nlbu54e	85	22	cell	cell	NN
cord-350019-4nlbu54e	85	23	lines	line	NNS
cord-350019-4nlbu54e	85	24	or	or	CC
cord-350019-4nlbu54e	85	25	tissues	tissue	NNS
cord-350019-4nlbu54e	85	26	during	during	IN
cord-350019-4nlbu54e	85	27	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	85	28	activation	activation	NN
cord-350019-4nlbu54e	85	29	.	.	.
cord-350019-4nlbu54e	86	1	For	for	IN
cord-350019-4nlbu54e	86	2	example	example	NN
cord-350019-4nlbu54e	86	3	,	,	,
cord-350019-4nlbu54e	86	4	lincRNA	lincrna	UH
cord-350019-4nlbu54e	86	5	-	-	:
cord-350019-4nlbu54e	86	6	Cox2	Cox2	NNP
cord-350019-4nlbu54e	86	7	was	be	VBD
cord-350019-4nlbu54e	86	8	initially	initially	RB
cord-350019-4nlbu54e	86	9	identified	identify	VBN
cord-350019-4nlbu54e	86	10	as	as	IN
cord-350019-4nlbu54e	86	11	an	an	DT
cord-350019-4nlbu54e	86	12	up	up	RB
cord-350019-4nlbu54e	86	13	-	-	HYPH
cord-350019-4nlbu54e	86	14	regulated	regulate	VBN
cord-350019-4nlbu54e	86	15	lncRNA	lncrna	NN
cord-350019-4nlbu54e	86	16	in	in	IN
cord-350019-4nlbu54e	86	17	murine	murine	JJ
cord-350019-4nlbu54e	86	18	dendritic	dendritic	JJ
cord-350019-4nlbu54e	86	19	cells	cell	NNS
cord-350019-4nlbu54e	86	20	following	follow	VBG
cord-350019-4nlbu54e	86	21	TLR4	TLR4	NNP
cord-350019-4nlbu54e	86	22	stimulation	stimulation	NN
cord-350019-4nlbu54e	86	23	[	[	-LRB-
cord-350019-4nlbu54e	86	24	60	60	CD
cord-350019-4nlbu54e	86	25	]	]	-RRB-
cord-350019-4nlbu54e	86	26	,	,	,
cord-350019-4nlbu54e	86	27	as	as	RB
cord-350019-4nlbu54e	86	28	well	well	RB
cord-350019-4nlbu54e	86	29	as	as	IN
cord-350019-4nlbu54e	86	30	murine	murine	JJ
cord-350019-4nlbu54e	86	31	bone	bone	NN
cord-350019-4nlbu54e	86	32	marrow	marrow	NN
cord-350019-4nlbu54e	86	33	derived	derive	VBN
cord-350019-4nlbu54e	86	34	macrophages	macrophage	NNS
cord-350019-4nlbu54e	86	35	(	(	-LRB-
cord-350019-4nlbu54e	86	36	BMDMs	bmdm	NNS
cord-350019-4nlbu54e	86	37	)	)	-RRB-
cord-350019-4nlbu54e	86	38	following	follow	VBG
cord-350019-4nlbu54e	86	39	TLR2-depedent	TLR2-depedent	NNP
cord-350019-4nlbu54e	86	40	stimulation	stimulation	NN
cord-350019-4nlbu54e	86	41	[	[	-LRB-
cord-350019-4nlbu54e	86	42	42	42	CD
cord-350019-4nlbu54e	86	43	]	]	-RRB-
cord-350019-4nlbu54e	86	44	.	.	.
cord-350019-4nlbu54e	87	1	Studies	study	NNS
cord-350019-4nlbu54e	87	2	have	have	VBP
cord-350019-4nlbu54e	87	3	also	also	RB
cord-350019-4nlbu54e	87	4	highlighted	highlight	VBN
cord-350019-4nlbu54e	87	5	the	the	DT
cord-350019-4nlbu54e	87	6	functions	function	NNS
cord-350019-4nlbu54e	87	7	of	of	IN
cord-350019-4nlbu54e	87	8	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	87	9	that	that	WDT
cord-350019-4nlbu54e	87	10	are	be	VBP
cord-350019-4nlbu54e	87	11	highly	highly	RB
cord-350019-4nlbu54e	87	12	downregulated	downregulate	VBN
cord-350019-4nlbu54e	87	13	post	post	JJ
cord-350019-4nlbu54e	87	14	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	87	15	activation	activation	NN
cord-350019-4nlbu54e	87	16	,	,	,
cord-350019-4nlbu54e	87	17	such	such	JJ
cord-350019-4nlbu54e	87	18	as	as	IN
cord-350019-4nlbu54e	87	19	lincRNA	lincrna	NN
cord-350019-4nlbu54e	87	20	-	-	HYPH
cord-350019-4nlbu54e	87	21	EPS	eps	NN
cord-350019-4nlbu54e	87	22	[	[	-LRB-
cord-350019-4nlbu54e	87	23	61	61	CD
cord-350019-4nlbu54e	87	24	]	]	-RRB-
cord-350019-4nlbu54e	87	25	and	and	CC
cord-350019-4nlbu54e	87	26	lnc13	lnc13	CD
cord-350019-4nlbu54e	87	27	[	[	-LRB-
cord-350019-4nlbu54e	87	28	62	62	CD
cord-350019-4nlbu54e	87	29	]	]	-RRB-
cord-350019-4nlbu54e	87	30	.	.	.
cord-350019-4nlbu54e	88	1	Both	both	DT
cord-350019-4nlbu54e	88	2	lincRNA	lincrna	RB
cord-350019-4nlbu54e	88	3	-	-	HYPH
cord-350019-4nlbu54e	88	4	Cox2	Cox2	NNP
cord-350019-4nlbu54e	88	5	and	and	CC
cord-350019-4nlbu54e	88	6	lincRNA	lincrna	NN
cord-350019-4nlbu54e	88	7	-	-	HYPH
cord-350019-4nlbu54e	88	8	EPS	EPS	NNP
cord-350019-4nlbu54e	88	9	were	be	VBD
cord-350019-4nlbu54e	88	10	discovered	discover	VBN
cord-350019-4nlbu54e	88	11	in	in	IN
cord-350019-4nlbu54e	88	12	BMDMs	BMDMs	NNP
cord-350019-4nlbu54e	88	13	post	post	NN
cord-350019-4nlbu54e	88	14	TLR	TLR	NNP
cord-350019-4nlbu54e	88	15	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	88	16	activation	activation	NN
cord-350019-4nlbu54e	88	17	and	and	CC
cord-350019-4nlbu54e	88	18	were	be	VBD
cord-350019-4nlbu54e	88	19	chosen	choose	VBN
cord-350019-4nlbu54e	88	20	for	for	IN
cord-350019-4nlbu54e	88	21	further	further	JJ
cord-350019-4nlbu54e	88	22	characterization	characterization	NN
cord-350019-4nlbu54e	88	23	based	base	VBN
cord-350019-4nlbu54e	88	24	on	on	IN
cord-350019-4nlbu54e	88	25	their	-PRON-	PRP$
cord-350019-4nlbu54e	88	26	extreme	extreme	JJ
cord-350019-4nlbu54e	88	27	expression	expression	NN
cord-350019-4nlbu54e	88	28	profile	profile	NN
cord-350019-4nlbu54e	88	29	.	.	.
cord-350019-4nlbu54e	89	1	LincRNA	lincrna	LS
cord-350019-4nlbu54e	89	2	-	-	:
cord-350019-4nlbu54e	89	3	Cox2	Cox2	NNP
cord-350019-4nlbu54e	89	4	is	be	VBZ
cord-350019-4nlbu54e	89	5	rapidly	rapidly	RB
cord-350019-4nlbu54e	89	6	upregulated	upregulate	VBN
cord-350019-4nlbu54e	89	7	and	and	CC
cord-350019-4nlbu54e	89	8	regulates	regulate	VBZ
cord-350019-4nlbu54e	89	9	a	a	DT
cord-350019-4nlbu54e	89	10	large	large	JJ
cord-350019-4nlbu54e	89	11	number	number	NN
cord-350019-4nlbu54e	89	12	of	of	IN
cord-350019-4nlbu54e	89	13	interferon	interferon	NN
cord-350019-4nlbu54e	89	14	stimulated	stimulate	VBN
cord-350019-4nlbu54e	89	15	genes	gene	NNS
cord-350019-4nlbu54e	89	16	(	(	-LRB-
cord-350019-4nlbu54e	89	17	ISGs	ISGs	NNP
cord-350019-4nlbu54e	89	18	)	)	-RRB-
cord-350019-4nlbu54e	89	19	and	and	CC
cord-350019-4nlbu54e	89	20	NF	NF	NNP
cord-350019-4nlbu54e	89	21	-	-	HYPH
cord-350019-4nlbu54e	89	22	κB	κb	CD
cord-350019-4nlbu54e	89	23	regulated	regulate	VBN
cord-350019-4nlbu54e	89	24	genes	gene	NNS
cord-350019-4nlbu54e	89	25	[	[	-LRB-
cord-350019-4nlbu54e	89	26	42	42	CD
cord-350019-4nlbu54e	89	27	]	]	-RRB-
cord-350019-4nlbu54e	89	28	.	.	.
cord-350019-4nlbu54e	90	1	Meanwhile	meanwhile	RB
cord-350019-4nlbu54e	90	2	,	,	,
cord-350019-4nlbu54e	90	3	lincRNA	lincrna	JJ
cord-350019-4nlbu54e	90	4	-	-	HYPH
cord-350019-4nlbu54e	90	5	EPS	EPS	NNP
cord-350019-4nlbu54e	90	6	is	be	VBZ
cord-350019-4nlbu54e	90	7	rapidly	rapidly	RB
cord-350019-4nlbu54e	90	8	down	down	RB
cord-350019-4nlbu54e	90	9	-	-	HYPH
cord-350019-4nlbu54e	90	10	regulated	regulate	VBN
cord-350019-4nlbu54e	90	11	during	during	IN
cord-350019-4nlbu54e	90	12	inflammation	inflammation	NN
cord-350019-4nlbu54e	90	13	and	and	CC
cord-350019-4nlbu54e	90	14	acts	act	VBZ
cord-350019-4nlbu54e	90	15	as	as	IN
cord-350019-4nlbu54e	90	16	an	an	DT
cord-350019-4nlbu54e	90	17	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	90	18	brake	brake	NN
cord-350019-4nlbu54e	90	19	on	on	IN
cord-350019-4nlbu54e	90	20	all	all	DT
cord-350019-4nlbu54e	90	21	ISGs	isg	NNS
cord-350019-4nlbu54e	90	22	during	during	IN
cord-350019-4nlbu54e	90	23	periods	period	NNS
cord-350019-4nlbu54e	90	24	of	of	IN
cord-350019-4nlbu54e	90	25	homeostasis	homeostasis	NN
cord-350019-4nlbu54e	90	26	[	[	-LRB-
cord-350019-4nlbu54e	90	27	61	61	CD
cord-350019-4nlbu54e	90	28	]	]	-RRB-
cord-350019-4nlbu54e	90	29	.	.	.
cord-350019-4nlbu54e	91	1	These	these	DT
cord-350019-4nlbu54e	91	2	are	be	VBP
cord-350019-4nlbu54e	91	3	just	just	RB
cord-350019-4nlbu54e	91	4	two	two	CD
cord-350019-4nlbu54e	91	5	examples	example	NNS
cord-350019-4nlbu54e	91	6	of	of	IN
cord-350019-4nlbu54e	91	7	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	91	8	that	that	WDT
cord-350019-4nlbu54e	91	9	have	have	VBP
cord-350019-4nlbu54e	91	10	provided	provide	VBN
cord-350019-4nlbu54e	91	11	critical	critical	JJ
cord-350019-4nlbu54e	91	12	insights	insight	NNS
cord-350019-4nlbu54e	91	13	into	into	IN
cord-350019-4nlbu54e	91	14	the	the	DT
cord-350019-4nlbu54e	91	15	roles	role	NNS
cord-350019-4nlbu54e	91	16	of	of	IN
cord-350019-4nlbu54e	91	17	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	91	18	in	in	IN
cord-350019-4nlbu54e	91	19	immunity	immunity	NN
cord-350019-4nlbu54e	91	20	.	.	.
cord-350019-4nlbu54e	92	1	For	for	IN
cord-350019-4nlbu54e	92	2	more	more	JJR
cord-350019-4nlbu54e	92	3	information	information	NN
cord-350019-4nlbu54e	92	4	on	on	IN
cord-350019-4nlbu54e	92	5	specific	specific	JJ
cord-350019-4nlbu54e	92	6	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	92	7	that	that	WDT
cord-350019-4nlbu54e	92	8	are	be	VBP
cord-350019-4nlbu54e	92	9	involved	involve	VBN
cord-350019-4nlbu54e	92	10	in	in	IN
cord-350019-4nlbu54e	92	11	innate	innate	JJ
cord-350019-4nlbu54e	92	12	immunity	immunity	NN
cord-350019-4nlbu54e	92	13	we	-PRON-	PRP
cord-350019-4nlbu54e	92	14	direct	direct	VBP
cord-350019-4nlbu54e	92	15	you	-PRON-	PRP
cord-350019-4nlbu54e	92	16	to	to	IN
cord-350019-4nlbu54e	92	17	the	the	DT
cord-350019-4nlbu54e	92	18	following	follow	VBG
cord-350019-4nlbu54e	92	19	recent	recent	JJ
cord-350019-4nlbu54e	92	20	reviews	review	NNS
cord-350019-4nlbu54e	92	21	on	on	IN
cord-350019-4nlbu54e	92	22	this	this	DT
cord-350019-4nlbu54e	92	23	topic	topic	NN
cord-350019-4nlbu54e	92	24	[	[	-LRB-
cord-350019-4nlbu54e	92	25	42	42	CD
cord-350019-4nlbu54e	92	26	,	,	,
cord-350019-4nlbu54e	92	27	47	47	CD
cord-350019-4nlbu54e	92	28	,	,	,
cord-350019-4nlbu54e	92	29	63	63	CD
cord-350019-4nlbu54e	92	30	]	]	-RRB-
cord-350019-4nlbu54e	92	31	.	.	.
cord-350019-4nlbu54e	93	1	In	in	IN
cord-350019-4nlbu54e	93	2	addition	addition	NN
cord-350019-4nlbu54e	93	3	to	to	IN
cord-350019-4nlbu54e	93	4	these	these	DT
cord-350019-4nlbu54e	93	5	bulk	bulk	NN
cord-350019-4nlbu54e	93	6	RNA	RNA	NNP
cord-350019-4nlbu54e	93	7	sequencing	sequencing	NN
cord-350019-4nlbu54e	93	8	studies	study	NNS
cord-350019-4nlbu54e	93	9	,	,	,
cord-350019-4nlbu54e	93	10	a	a	DT
cord-350019-4nlbu54e	93	11	small	small	JJ
cord-350019-4nlbu54e	93	12	number	number	NN
cord-350019-4nlbu54e	93	13	of	of	IN
cord-350019-4nlbu54e	93	14	single	single	JJ
cord-350019-4nlbu54e	93	15	cell	cell	NN
cord-350019-4nlbu54e	93	16	RNA	rna	NN
cord-350019-4nlbu54e	93	17	sequencing	sequencing	NN
cord-350019-4nlbu54e	93	18	studies	study	NNS
cord-350019-4nlbu54e	93	19	have	have	VBP
cord-350019-4nlbu54e	93	20	been	be	VBN
cord-350019-4nlbu54e	93	21	performed	perform	VBN
cord-350019-4nlbu54e	93	22	in	in	IN
cord-350019-4nlbu54e	93	23	both	both	DT
cord-350019-4nlbu54e	93	24	human	human	JJ
cord-350019-4nlbu54e	93	25	and	and	CC
cord-350019-4nlbu54e	93	26	mouse	mouse	NN
cord-350019-4nlbu54e	93	27	that	that	WDT
cord-350019-4nlbu54e	93	28	can	can	MD
cord-350019-4nlbu54e	93	29	be	be	VB
cord-350019-4nlbu54e	93	30	utilized	utilize	VBN
cord-350019-4nlbu54e	93	31	to	to	TO
cord-350019-4nlbu54e	93	32	examine	examine	VB
cord-350019-4nlbu54e	93	33	differential	differential	JJ
cord-350019-4nlbu54e	93	34	expression	expression	NN
cord-350019-4nlbu54e	93	35	of	of	IN
cord-350019-4nlbu54e	93	36	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	93	37	in	in	IN
cord-350019-4nlbu54e	93	38	basal	basal	NN
cord-350019-4nlbu54e	93	39	versus	versus	IN
cord-350019-4nlbu54e	93	40	treatment	treatment	NN
cord-350019-4nlbu54e	93	41	conditions	condition	NNS
cord-350019-4nlbu54e	93	42	or	or	CC
cord-350019-4nlbu54e	93	43	between	between	IN
cord-350019-4nlbu54e	93	44	cell	cell	NN
cord-350019-4nlbu54e	93	45	types	type	NNS
cord-350019-4nlbu54e	93	46	[	[	-LRB-
cord-350019-4nlbu54e	93	47	64	64	CD
cord-350019-4nlbu54e	93	48	]	]	-RRB-
cord-350019-4nlbu54e	93	49	[	[	-LRB-
cord-350019-4nlbu54e	93	50	65	65	CD
cord-350019-4nlbu54e	93	51	]	]	-RRB-
cord-350019-4nlbu54e	94	1	[	[	-LRB-
cord-350019-4nlbu54e	94	2	66	66	CD
cord-350019-4nlbu54e	94	3	]	]	-RRB-
cord-350019-4nlbu54e	95	1	[	[	-LRB-
cord-350019-4nlbu54e	95	2	67	67	CD
cord-350019-4nlbu54e	95	3	]	]	-RRB-
cord-350019-4nlbu54e	95	4	[	[	-LRB-
cord-350019-4nlbu54e	95	5	68	68	CD
cord-350019-4nlbu54e	95	6	]	]	-RRB-
cord-350019-4nlbu54e	95	7	.	.	.
cord-350019-4nlbu54e	96	1	Numerous	Numerous	NNP
cord-350019-4nlbu54e	96	2	RNA	RNA	NNP
cord-350019-4nlbu54e	96	3	-	-	HYPH
cord-350019-4nlbu54e	96	4	seq	seq	NNP
cord-350019-4nlbu54e	96	5	(	(	-LRB-
cord-350019-4nlbu54e	96	6	both	both	DT
cord-350019-4nlbu54e	96	7	bulk	bulk	JJ
cord-350019-4nlbu54e	96	8	and	and	CC
cord-350019-4nlbu54e	96	9	single	single	JJ
cord-350019-4nlbu54e	96	10	cell	cell	NN
cord-350019-4nlbu54e	96	11	)	)	-RRB-
cord-350019-4nlbu54e	96	12	datasets	dataset	NNS
cord-350019-4nlbu54e	96	13	are	be	VBP
cord-350019-4nlbu54e	96	14	available	available	JJ
cord-350019-4nlbu54e	96	15	for	for	IN
cord-350019-4nlbu54e	96	16	a	a	DT
cord-350019-4nlbu54e	96	17	variety	variety	NN
cord-350019-4nlbu54e	96	18	of	of	IN
cord-350019-4nlbu54e	96	19	primary	primary	JJ
cord-350019-4nlbu54e	96	20	cells	cell	NNS
cord-350019-4nlbu54e	96	21	,	,	,
cord-350019-4nlbu54e	96	22	cell	cell	NN
cord-350019-4nlbu54e	96	23	lines	line	NNS
cord-350019-4nlbu54e	96	24	or	or	CC
cord-350019-4nlbu54e	96	25	tissues	tissue	NNS
cord-350019-4nlbu54e	96	26	of	of	IN
cord-350019-4nlbu54e	96	27	interest	interest	NN
cord-350019-4nlbu54e	96	28	either	either	CC
cord-350019-4nlbu54e	96	29	basally	basally	RB
cord-350019-4nlbu54e	96	30	or	or	CC
cord-350019-4nlbu54e	96	31	under	under	IN
cord-350019-4nlbu54e	96	32	a	a	DT
cord-350019-4nlbu54e	96	33	multitude	multitude	NN
cord-350019-4nlbu54e	96	34	of	of	IN
cord-350019-4nlbu54e	96	35	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	96	36	or	or	CC
cord-350019-4nlbu54e	96	37	cellular	cellular	JJ
cord-350019-4nlbu54e	96	38	differentiation	differentiation	NN
cord-350019-4nlbu54e	96	39	treatments	treatment	NNS
cord-350019-4nlbu54e	96	40	.	.	.
cord-350019-4nlbu54e	97	1	These	these	DT
cord-350019-4nlbu54e	97	2	datasets	dataset	NNS
cord-350019-4nlbu54e	97	3	outlined	outline	VBN
cord-350019-4nlbu54e	97	4	in	in	IN
cord-350019-4nlbu54e	97	5	Table	Table	NNP
cord-350019-4nlbu54e	97	6	1	1	CD
cord-350019-4nlbu54e	97	7	[	[	-LRB-
cord-350019-4nlbu54e	97	8	42,46,74	42,46,74	CD
cord-350019-4nlbu54e	97	9	-	-	SYM
cord-350019-4nlbu54e	97	10	77	77	CD
cord-350019-4nlbu54e	97	11	,	,	,
cord-350019-4nlbu54e	97	12	57	57	CD
cord-350019-4nlbu54e	97	13	,	,	,
cord-350019-4nlbu54e	97	14	61	61	CD
cord-350019-4nlbu54e	97	15	,	,	,
cord-350019-4nlbu54e	97	16	64	64	CD
cord-350019-4nlbu54e	97	17	,	,	,
cord-350019-4nlbu54e	97	18	69	69	CD
cord-350019-4nlbu54e	97	19	-	-	SYM
cord-350019-4nlbu54e	97	20	73	73	CD
cord-350019-4nlbu54e	97	21	]	]	-RRB-
cord-350019-4nlbu54e	97	22	and	and	CC
cord-350019-4nlbu54e	97	23	Table	table	NN
cord-350019-4nlbu54e	97	24	2	2	CD
cord-350019-4nlbu54e	97	25	[	[	-LRB-
cord-350019-4nlbu54e	97	26	53,56	53,56	CD
cord-350019-4nlbu54e	97	27	,	,	,
cord-350019-4nlbu54e	97	28	82	82	CD
cord-350019-4nlbu54e	97	29	-	-	SYM
cord-350019-4nlbu54e	97	30	90	90	CD
cord-350019-4nlbu54e	97	31	,	,	,
cord-350019-4nlbu54e	97	32	65	65	CD
cord-350019-4nlbu54e	97	33	-	-	SYM
cord-350019-4nlbu54e	97	34	68	68	CD
cord-350019-4nlbu54e	97	35	,	,	,
cord-350019-4nlbu54e	97	36	78	78	CD
cord-350019-4nlbu54e	97	37	-	-	SYM
cord-350019-4nlbu54e	97	38	81	81	CD
cord-350019-4nlbu54e	97	39	]	]	-RRB-
cord-350019-4nlbu54e	97	40	provide	provide	VB
cord-350019-4nlbu54e	97	41	a	a	DT
cord-350019-4nlbu54e	97	42	rich	rich	JJ
cord-350019-4nlbu54e	97	43	source	source	NN
cord-350019-4nlbu54e	97	44	of	of	IN
cord-350019-4nlbu54e	97	45	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	97	46	for	for	IN
cord-350019-4nlbu54e	97	47	further	further	JJ
cord-350019-4nlbu54e	97	48	investigation	investigation	NN
cord-350019-4nlbu54e	97	49	.	.	.
cord-350019-4nlbu54e	98	1	EVLncRNAs	EVLncRNAs	NNP
cord-350019-4nlbu54e	98	2	[	[	-LRB-
cord-350019-4nlbu54e	98	3	91	91	CD
cord-350019-4nlbu54e	98	4	]	]	-RRB-
cord-350019-4nlbu54e	98	5	,	,	,
cord-350019-4nlbu54e	98	6	NONCODE	NONCODE	NNP
cord-350019-4nlbu54e	98	7	[	[	-LRB-
cord-350019-4nlbu54e	98	8	92	92	CD
cord-350019-4nlbu54e	98	9	]	]	-RRB-
cord-350019-4nlbu54e	98	10	,	,	,
cord-350019-4nlbu54e	98	11	or	or	CC
cord-350019-4nlbu54e	98	12	LNCipedia	LNCipedia	NNP
cord-350019-4nlbu54e	99	1	[	[	-LRB-
cord-350019-4nlbu54e	99	2	93	93	CD
cord-350019-4nlbu54e	99	3	]	]	-RRB-
cord-350019-4nlbu54e	99	4	are	be	VBP
cord-350019-4nlbu54e	99	5	databases	database	NNS
cord-350019-4nlbu54e	99	6	that	that	WDT
cord-350019-4nlbu54e	99	7	categorize	categorize	VBP
cord-350019-4nlbu54e	99	8	published	publish	VBN
cord-350019-4nlbu54e	99	9	information	information	NN
cord-350019-4nlbu54e	99	10	on	on	IN
cord-350019-4nlbu54e	99	11	all	all	DT
cord-350019-4nlbu54e	99	12	annotated	annotate	VBN
cord-350019-4nlbu54e	99	13	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	99	14	.	.	.
cord-350019-4nlbu54e	100	1	These	these	DT
cord-350019-4nlbu54e	100	2	databases	database	NNS
cord-350019-4nlbu54e	100	3	can	can	MD
cord-350019-4nlbu54e	100	4	be	be	VB
cord-350019-4nlbu54e	100	5	utilized	utilize	VBN
cord-350019-4nlbu54e	100	6	to	to	TO
cord-350019-4nlbu54e	100	7	determine	determine	VB
cord-350019-4nlbu54e	100	8	if	if	IN
cord-350019-4nlbu54e	100	9	a	a	DT
cord-350019-4nlbu54e	100	10	lncRNA	lncrna	NN
cord-350019-4nlbu54e	100	11	is	be	VBZ
cord-350019-4nlbu54e	100	12	experimentally	experimentally	RB
cord-350019-4nlbu54e	100	13	validated	validate	VBN
cord-350019-4nlbu54e	100	14	within	within	IN
cord-350019-4nlbu54e	100	15	one	one	CD
cord-350019-4nlbu54e	100	16	or	or	CC
cord-350019-4nlbu54e	100	17	more	more	JJR
cord-350019-4nlbu54e	100	18	studies	study	NNS
cord-350019-4nlbu54e	100	19	.	.	.
cord-350019-4nlbu54e	101	1	Additionally	additionally	RB
cord-350019-4nlbu54e	101	2	,	,	,
cord-350019-4nlbu54e	101	3	these	these	DT
cord-350019-4nlbu54e	101	4	databases	database	NNS
cord-350019-4nlbu54e	101	5	can	can	MD
cord-350019-4nlbu54e	101	6	provide	provide	VB
cord-350019-4nlbu54e	101	7	information	information	NN
cord-350019-4nlbu54e	101	8	on	on	IN
cord-350019-4nlbu54e	101	9	whether	whether	IN
cord-350019-4nlbu54e	101	10	a	a	DT
cord-350019-4nlbu54e	101	11	lncRNA	lncrna	NN
cord-350019-4nlbu54e	101	12	possesses	possess	VBZ
cord-350019-4nlbu54e	101	13	multiple	multiple	JJ
cord-350019-4nlbu54e	101	14	isoforms	isoform	NNS
cord-350019-4nlbu54e	101	15	,	,	,
cord-350019-4nlbu54e	101	16	secondary	secondary	JJ
cord-350019-4nlbu54e	101	17	structure	structure	NN
cord-350019-4nlbu54e	101	18	,	,	,
cord-350019-4nlbu54e	101	19	cross	cross	NN
cord-350019-4nlbu54e	101	20	-	-	JJ
cord-350019-4nlbu54e	101	21	species	species	JJ
cord-350019-4nlbu54e	101	22	conservation	conservation	NN
cord-350019-4nlbu54e	101	23	and/or	and/or	CC
cord-350019-4nlbu54e	101	24	disease	disease	NN
cord-350019-4nlbu54e	101	25	-	-	HYPH
cord-350019-4nlbu54e	101	26	association	association	NN
cord-350019-4nlbu54e	101	27	via	via	IN
cord-350019-4nlbu54e	101	28	presence	presence	NN
cord-350019-4nlbu54e	101	29	of	of	IN
cord-350019-4nlbu54e	101	30	single	single	JJ
cord-350019-4nlbu54e	101	31	nucleotide	nucleotide	JJ
cord-350019-4nlbu54e	101	32	polymorphisms	polymorphism	NNS
cord-350019-4nlbu54e	101	33	(	(	-LRB-
cord-350019-4nlbu54e	101	34	SNPs	SNPs	NNP
cord-350019-4nlbu54e	101	35	)	)	-RRB-
cord-350019-4nlbu54e	101	36	.	.	.
cord-350019-4nlbu54e	102	1	Multiple	multiple	JJ
cord-350019-4nlbu54e	102	2	studies	study	NNS
cord-350019-4nlbu54e	102	3	have	have	VBP
cord-350019-4nlbu54e	102	4	demonstrated	demonstrate	VBN
cord-350019-4nlbu54e	102	5	that	that	IN
cord-350019-4nlbu54e	102	6	lncRNA	lncrna	NN
cord-350019-4nlbu54e	102	7	expression	expression	NN
cord-350019-4nlbu54e	102	8	is	be	VBZ
cord-350019-4nlbu54e	102	9	more	more	JJR
cord-350019-4nlbu54e	102	10	cell	cell	NN
cord-350019-4nlbu54e	102	11	type	type	NN
cord-350019-4nlbu54e	102	12	specific	specific	JJ
cord-350019-4nlbu54e	102	13	compared	compare	VBN
cord-350019-4nlbu54e	102	14	to	to	IN
cord-350019-4nlbu54e	102	15	protein	protein	NN
cord-350019-4nlbu54e	102	16	-	-	HYPH
cord-350019-4nlbu54e	102	17	coding	code	VBG
cord-350019-4nlbu54e	102	18	genes	gene	NNS
cord-350019-4nlbu54e	102	19	[	[	-LRB-
cord-350019-4nlbu54e	102	20	94	94	CD
cord-350019-4nlbu54e	102	21	]	]	-RRB-
cord-350019-4nlbu54e	102	22	[	[	-LRB-
cord-350019-4nlbu54e	102	23	95	95	CD
cord-350019-4nlbu54e	102	24	]	]	-RRB-
cord-350019-4nlbu54e	102	25	[	[	-LRB-
cord-350019-4nlbu54e	102	26	96	96	CD
cord-350019-4nlbu54e	102	27	]	]	-RRB-
cord-350019-4nlbu54e	102	28	.	.	.
cord-350019-4nlbu54e	103	1	Such	such	JJ
cord-350019-4nlbu54e	103	2	specific	specific	JJ
cord-350019-4nlbu54e	103	3	expression	expression	NN
cord-350019-4nlbu54e	103	4	patterns	pattern	NNS
cord-350019-4nlbu54e	103	5	can	can	MD
cord-350019-4nlbu54e	103	6	often	often	RB
cord-350019-4nlbu54e	103	7	provide	provide	VB
cord-350019-4nlbu54e	103	8	important	important	JJ
cord-350019-4nlbu54e	103	9	clues	clue	NNS
cord-350019-4nlbu54e	103	10	into	into	IN
cord-350019-4nlbu54e	103	11	the	the	DT
cord-350019-4nlbu54e	103	12	specific	specific	JJ
cord-350019-4nlbu54e	103	13	biology	biology	NN
cord-350019-4nlbu54e	103	14	that	that	WDT
cord-350019-4nlbu54e	103	15	the	the	DT
cord-350019-4nlbu54e	103	16	gene	gene	NN
cord-350019-4nlbu54e	103	17	could	could	MD
cord-350019-4nlbu54e	103	18	be	be	VB
cord-350019-4nlbu54e	103	19	involved	involve	VBN
cord-350019-4nlbu54e	103	20	in	in	IN
cord-350019-4nlbu54e	103	21	[	[	-LRB-
cord-350019-4nlbu54e	103	22	46	46	CD
cord-350019-4nlbu54e	103	23	]	]	-RRB-
cord-350019-4nlbu54e	104	1	(	(	-LRB-
cord-350019-4nlbu54e	104	2	Tables	table	NNS
cord-350019-4nlbu54e	104	3	1	1	CD
cord-350019-4nlbu54e	104	4	and	and	CC
cord-350019-4nlbu54e	104	5	 	 	_SP
cord-350019-4nlbu54e	104	6	2	2	CD
cord-350019-4nlbu54e	104	7	)	)	-RRB-
cord-350019-4nlbu54e	104	8	.	.	.
cord-350019-4nlbu54e	105	1	A	a	DT
cord-350019-4nlbu54e	105	2	variety	variety	NN
cord-350019-4nlbu54e	105	3	of	of	IN
cord-350019-4nlbu54e	105	4	consortiums	consortium	NNS
cord-350019-4nlbu54e	105	5	exist	exist	VBP
cord-350019-4nlbu54e	105	6	for	for	IN
cord-350019-4nlbu54e	105	7	both	both	CC
cord-350019-4nlbu54e	105	8	human	human	JJ
cord-350019-4nlbu54e	105	9	and	and	CC
cord-350019-4nlbu54e	105	10	mouse	mouse	NN
cord-350019-4nlbu54e	105	11	and	and	CC
cord-350019-4nlbu54e	105	12	can	can	MD
cord-350019-4nlbu54e	105	13	be	be	VB
cord-350019-4nlbu54e	105	14	utilized	utilize	VBN
cord-350019-4nlbu54e	105	15	to	to	TO
cord-350019-4nlbu54e	105	16	determine	determine	VB
cord-350019-4nlbu54e	105	17	cell	cell	NN
cord-350019-4nlbu54e	105	18	type	type	NN
cord-350019-4nlbu54e	105	19	specificity	specificity	NN
cord-350019-4nlbu54e	105	20	of	of	IN
cord-350019-4nlbu54e	105	21	a	a	DT
cord-350019-4nlbu54e	105	22	lncRNA	lncrna	NN
cord-350019-4nlbu54e	105	23	candidate	candidate	NN
cord-350019-4nlbu54e	105	24	further	further	RB
cord-350019-4nlbu54e	105	25	.	.	.
cord-350019-4nlbu54e	106	1	For	for	IN
cord-350019-4nlbu54e	106	2	instance	instance	NN
cord-350019-4nlbu54e	106	3	,	,	,
cord-350019-4nlbu54e	106	4	GTEx	GTEx	NNP
cord-350019-4nlbu54e	106	5	[	[	-LRB-
cord-350019-4nlbu54e	106	6	97	97	CD
cord-350019-4nlbu54e	106	7	]	]	-RRB-
cord-350019-4nlbu54e	106	8	and	and	CC
cord-350019-4nlbu54e	106	9	XENA	XENA	NNP
cord-350019-4nlbu54e	106	10	[	[	-LRB-
cord-350019-4nlbu54e	106	11	98	98	CD
cord-350019-4nlbu54e	106	12	]	]	-RRB-
cord-350019-4nlbu54e	106	13	are	be	VBP
cord-350019-4nlbu54e	106	14	two	two	CD
cord-350019-4nlbu54e	106	15	websites	website	NNS
cord-350019-4nlbu54e	106	16	that	that	WDT
cord-350019-4nlbu54e	106	17	include	include	VBP
cord-350019-4nlbu54e	106	18	RNA	RNA	NNP
cord-350019-4nlbu54e	106	19	sequencing	sequence	VBG
cord-350019-4nlbu54e	106	20	on	on	IN
cord-350019-4nlbu54e	106	21	healthy	healthy	JJ
cord-350019-4nlbu54e	106	22	primary	primary	JJ
cord-350019-4nlbu54e	106	23	human	human	JJ
cord-350019-4nlbu54e	106	24	tissue	tissue	NN
cord-350019-4nlbu54e	106	25	samples	sample	NNS
cord-350019-4nlbu54e	106	26	,	,	,
cord-350019-4nlbu54e	106	27	in	in	IN
cord-350019-4nlbu54e	106	28	addition	addition	NN
cord-350019-4nlbu54e	106	29	to	to	IN
cord-350019-4nlbu54e	106	30	samples	sample	NNS
cord-350019-4nlbu54e	106	31	from	from	IN
cord-350019-4nlbu54e	106	32	patients	patient	NNS
cord-350019-4nlbu54e	106	33	with	with	IN
cord-350019-4nlbu54e	106	34	diagnosed	diagnosed	JJ
cord-350019-4nlbu54e	106	35	cancers	cancer	NNS
cord-350019-4nlbu54e	106	36	.	.	.
cord-350019-4nlbu54e	107	1	This	this	DT
cord-350019-4nlbu54e	107	2	will	will	MD
cord-350019-4nlbu54e	107	3	further	further	RB
cord-350019-4nlbu54e	107	4	assist	assist	VB
cord-350019-4nlbu54e	107	5	the	the	DT
cord-350019-4nlbu54e	107	6	initial	initial	JJ
cord-350019-4nlbu54e	107	7	understanding	understanding	NN
cord-350019-4nlbu54e	107	8	of	of	IN
cord-350019-4nlbu54e	107	9	the	the	DT
cord-350019-4nlbu54e	107	10	expression	expression	NN
cord-350019-4nlbu54e	107	11	of	of	IN
cord-350019-4nlbu54e	107	12	the	the	DT
cord-350019-4nlbu54e	107	13	lncRNA	lncrna	NN
cord-350019-4nlbu54e	107	14	in	in	IN
cord-350019-4nlbu54e	107	15	specific	specific	JJ
cord-350019-4nlbu54e	107	16	tissues	tissue	NNS
cord-350019-4nlbu54e	107	17	as	as	RB
cord-350019-4nlbu54e	107	18	well	well	RB
cord-350019-4nlbu54e	107	19	as	as	IN
cord-350019-4nlbu54e	107	20	obtaining	obtain	VBG
cord-350019-4nlbu54e	107	21	information	information	NN
cord-350019-4nlbu54e	107	22	on	on	IN
cord-350019-4nlbu54e	107	23	whether	whether	IN
cord-350019-4nlbu54e	107	24	a	a	DT
cord-350019-4nlbu54e	107	25	lncRNA	lncrna	NN
cord-350019-4nlbu54e	107	26	is	be	VBZ
cord-350019-4nlbu54e	107	27	involved	involve	VBN
cord-350019-4nlbu54e	107	28	in	in	IN
cord-350019-4nlbu54e	107	29	cancer	cancer	NN
cord-350019-4nlbu54e	107	30	.	.	.
cord-350019-4nlbu54e	108	1	In	in	IN
cord-350019-4nlbu54e	108	2	contrast	contrast	NN
cord-350019-4nlbu54e	108	3	,	,	,
cord-350019-4nlbu54e	108	4	if	if	IN
cord-350019-4nlbu54e	108	5	a	a	DT
cord-350019-4nlbu54e	108	6	researcher	researcher	NN
cord-350019-4nlbu54e	108	7	is	be	VBZ
cord-350019-4nlbu54e	108	8	studying	study	VBG
cord-350019-4nlbu54e	108	9	a	a	DT
cord-350019-4nlbu54e	108	10	mouse	mouse	NN
cord-350019-4nlbu54e	108	11	candidate	candidate	NN
cord-350019-4nlbu54e	108	12	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	108	13	,	,	,
cord-350019-4nlbu54e	108	14	the	the	DT
cord-350019-4nlbu54e	108	15	Mouse	Mouse	NNP
cord-350019-4nlbu54e	108	16	Cell	Cell	NNP
cord-350019-4nlbu54e	108	17	Atlas	Atlas	NNP
cord-350019-4nlbu54e	108	18	(	(	-LRB-
cord-350019-4nlbu54e	108	19	MCA	MCA	NNP
cord-350019-4nlbu54e	108	20	)	)	-RRB-
cord-350019-4nlbu54e	108	21	[	[	-LRB-
cord-350019-4nlbu54e	108	22	99	99	CD
cord-350019-4nlbu54e	108	23	]	]	-RRB-
cord-350019-4nlbu54e	108	24	,	,	,
cord-350019-4nlbu54e	108	25	as	as	RB
cord-350019-4nlbu54e	108	26	well	well	RB
cord-350019-4nlbu54e	108	27	as	as	IN
cord-350019-4nlbu54e	108	28	Tabula	Tabula	NNP
cord-350019-4nlbu54e	108	29	Muris	Muris	NNP
cord-350019-4nlbu54e	108	30	[	[	-LRB-
cord-350019-4nlbu54e	108	31	100	100	CD
cord-350019-4nlbu54e	108	32	]	]	-RRB-
cord-350019-4nlbu54e	108	33	are	be	VBP
cord-350019-4nlbu54e	108	34	excellent	excellent	JJ
cord-350019-4nlbu54e	108	35	tools	tool	NNS
cord-350019-4nlbu54e	108	36	to	to	TO
cord-350019-4nlbu54e	108	37	assess	assess	VB
cord-350019-4nlbu54e	108	38	specificity	specificity	NN
cord-350019-4nlbu54e	108	39	in	in	IN
cord-350019-4nlbu54e	108	40	cellular	cellular	JJ
cord-350019-4nlbu54e	108	41	expression	expression	NN
cord-350019-4nlbu54e	108	42	,	,	,
cord-350019-4nlbu54e	108	43	as	as	RB
cord-350019-4nlbu54e	108	44	well	well	RB
cord-350019-4nlbu54e	108	45	as	as	IN
cord-350019-4nlbu54e	108	46	differential	differential	JJ
cord-350019-4nlbu54e	108	47	splicing	splicing	NN
cord-350019-4nlbu54e	108	48	isoforms	isoform	NNS
cord-350019-4nlbu54e	108	49	amongst	amongst	IN
cord-350019-4nlbu54e	108	50	differentiated	differentiated	JJ
cord-350019-4nlbu54e	108	51	cell	cell	NN
cord-350019-4nlbu54e	108	52	types	type	NNS
cord-350019-4nlbu54e	108	53	.	.	.
cord-350019-4nlbu54e	109	1	Additional	additional	JJ
cord-350019-4nlbu54e	109	2	websites	website	NNS
cord-350019-4nlbu54e	109	3	for	for	IN
cord-350019-4nlbu54e	109	4	mouse	mouse	NN
cord-350019-4nlbu54e	109	5	and	and	CC
cord-350019-4nlbu54e	109	6	human	human	JJ
cord-350019-4nlbu54e	109	7	expression	expression	NN
cord-350019-4nlbu54e	109	8	datasets	dataset	NNS
cord-350019-4nlbu54e	109	9	can	can	MD
cord-350019-4nlbu54e	109	10	be	be	VB
cord-350019-4nlbu54e	109	11	found	find	VBN
cord-350019-4nlbu54e	109	12	at	at	IN
cord-350019-4nlbu54e	109	13	the	the	DT
cord-350019-4nlbu54e	109	14	ENCODE	encode	NN
cord-350019-4nlbu54e	109	15	project	project	NN
cord-350019-4nlbu54e	109	16	[	[	-LRB-
cord-350019-4nlbu54e	109	17	101	101	CD
cord-350019-4nlbu54e	109	18	]	]	-RRB-
cord-350019-4nlbu54e	109	19	,	,	,
cord-350019-4nlbu54e	109	20	the	the	DT
cord-350019-4nlbu54e	109	21	European	European	NNP
cord-350019-4nlbu54e	109	22	Bioinformatics	Bioinformatics	NNP
cord-350019-4nlbu54e	109	23	Institute	Institute	NNP
cord-350019-4nlbu54e	109	24	Expression	Expression	NNP
cord-350019-4nlbu54e	109	25	and	and	CC
cord-350019-4nlbu54e	109	26	the	the	DT
cord-350019-4nlbu54e	109	27	FANTOM	FANTOM	NNP
cord-350019-4nlbu54e	109	28	projects	project	NNS
cord-350019-4nlbu54e	109	29	[	[	-LRB-
cord-350019-4nlbu54e	109	30	102	102	CD
cord-350019-4nlbu54e	109	31	]	]	-RRB-
cord-350019-4nlbu54e	109	32	.	.	.
cord-350019-4nlbu54e	110	1	These	these	DT
cord-350019-4nlbu54e	110	2	sites	site	NNS
cord-350019-4nlbu54e	110	3	are	be	VBP
cord-350019-4nlbu54e	110	4	filled	fill	VBN
cord-350019-4nlbu54e	110	5	with	with	IN
cord-350019-4nlbu54e	110	6	raw	raw	JJ
cord-350019-4nlbu54e	110	7	and	and	CC
cord-350019-4nlbu54e	110	8	analyzed	analyze	VBN
cord-350019-4nlbu54e	110	9	data	data	NN
cord-350019-4nlbu54e	110	10	sets	set	NNS
cord-350019-4nlbu54e	110	11	from	from	IN
cord-350019-4nlbu54e	110	12	either	either	DT
cord-350019-4nlbu54e	110	13	single	single	JJ
cord-350019-4nlbu54e	110	14	cell	cell	NN
cord-350019-4nlbu54e	110	15	or	or	CC
cord-350019-4nlbu54e	110	16	bulk	bulk	NN
cord-350019-4nlbu54e	110	17	RNA	RNA	NNP
cord-350019-4nlbu54e	110	18	sequencing	sequencing	NN
cord-350019-4nlbu54e	110	19	from	from	IN
cord-350019-4nlbu54e	110	20	primary	primary	JJ
cord-350019-4nlbu54e	110	21	cells	cell	NNS
cord-350019-4nlbu54e	110	22	,	,	,
cord-350019-4nlbu54e	110	23	tissues	tissue	NNS
cord-350019-4nlbu54e	110	24	or	or	CC
cord-350019-4nlbu54e	110	25	immortalized	immortalize	VBN
cord-350019-4nlbu54e	110	26	cells	cell	NNS
cord-350019-4nlbu54e	110	27	ready	ready	JJ
cord-350019-4nlbu54e	110	28	to	to	TO
cord-350019-4nlbu54e	110	29	use	use	VB
cord-350019-4nlbu54e	110	30	to	to	TO
cord-350019-4nlbu54e	110	31	determine	determine	VB
cord-350019-4nlbu54e	110	32	the	the	DT
cord-350019-4nlbu54e	110	33	statistical	statistical	JJ
cord-350019-4nlbu54e	110	34	significance	significance	NN
cord-350019-4nlbu54e	110	35	of	of	IN
cord-350019-4nlbu54e	110	36	expression	expression	NN
cord-350019-4nlbu54e	110	37	for	for	IN
cord-350019-4nlbu54e	110	38	any	any	DT
cord-350019-4nlbu54e	110	39	annotated	annotated	JJ
cord-350019-4nlbu54e	110	40	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	110	41	candidate	candidate	NN
cord-350019-4nlbu54e	110	42	.	.	.
cord-350019-4nlbu54e	111	1	Transcriptional	Transcriptional	NNP
cord-350019-4nlbu54e	111	2	activation	activation	NN
cord-350019-4nlbu54e	111	3	is	be	VBZ
cord-350019-4nlbu54e	111	4	depicted	depict	VBN
cord-350019-4nlbu54e	111	5	basally	basally	RB
cord-350019-4nlbu54e	111	6	'	'	``
cord-350019-4nlbu54e	111	7	Part	part	NN
cord-350019-4nlbu54e	111	8	I	-PRON-	PRP
cord-350019-4nlbu54e	111	9	'	'	''
cord-350019-4nlbu54e	111	10	,	,	,
cord-350019-4nlbu54e	111	11	as	as	RB
cord-350019-4nlbu54e	111	12	well	well	RB
cord-350019-4nlbu54e	111	13	as	as	IN
cord-350019-4nlbu54e	111	14	during	during	IN
cord-350019-4nlbu54e	111	15	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	111	16	activation	activation	NN
cord-350019-4nlbu54e	111	17	'	'	''
cord-350019-4nlbu54e	111	18	Part	Part	NNP
cord-350019-4nlbu54e	111	19	II	II	NNP
cord-350019-4nlbu54e	111	20	'	'	POS
cord-350019-4nlbu54e	111	21	following	follow	VBG
cord-350019-4nlbu54e	111	22	stimulation	stimulation	NN
cord-350019-4nlbu54e	111	23	of	of	IN
cord-350019-4nlbu54e	111	24	a	a	DT
cord-350019-4nlbu54e	111	25	pattern	pattern	NN
cord-350019-4nlbu54e	111	26	recognition	recognition	NN
cord-350019-4nlbu54e	111	27	receptor	receptor	NN
cord-350019-4nlbu54e	111	28	(	(	-LRB-
cord-350019-4nlbu54e	111	29	PRR	PRR	NNP
cord-350019-4nlbu54e	111	30	)	)	-RRB-
cord-350019-4nlbu54e	111	31	.	.	.
cord-350019-4nlbu54e	112	1	Three	three	CD
cord-350019-4nlbu54e	112	2	lncRNA	lncRNA	NNS
cord-350019-4nlbu54e	112	3	examples	example	NNS
cord-350019-4nlbu54e	112	4	genes	gene	NNS
cord-350019-4nlbu54e	112	5	are	be	VBP
cord-350019-4nlbu54e	112	6	shown	show	VBN
cord-350019-4nlbu54e	112	7	A	A	NNP
cord-350019-4nlbu54e	112	8	,	,	,
cord-350019-4nlbu54e	112	9	B	B	NNP
cord-350019-4nlbu54e	112	10	and	and	CC
cord-350019-4nlbu54e	112	11	C.	C.	NNP
cord-350019-4nlbu54e	112	12	Part	Part	NNP
cord-350019-4nlbu54e	112	13	III	III	NNP
cord-350019-4nlbu54e	112	14	depicts	depict	VBZ
cord-350019-4nlbu54e	112	15	how	how	WRB
cord-350019-4nlbu54e	112	16	a	a	DT
cord-350019-4nlbu54e	112	17	lncRNA	lncrna	NN
cord-350019-4nlbu54e	112	18	can	can	MD
cord-350019-4nlbu54e	112	19	undergo	undergo	VB
cord-350019-4nlbu54e	112	20	differential	differential	JJ
cord-350019-4nlbu54e	112	21	isoform	isoform	NN
cord-350019-4nlbu54e	112	22	expression	expression	NN
cord-350019-4nlbu54e	112	23	which	which	WDT
cord-350019-4nlbu54e	112	24	is	be	VBZ
cord-350019-4nlbu54e	112	25	regulated	regulate	VBN
cord-350019-4nlbu54e	112	26	co	co	NN
cord-350019-4nlbu54e	112	27	-	-	NN
cord-350019-4nlbu54e	112	28	transcriptionally	transcriptionally	RB
cord-350019-4nlbu54e	112	29	.	.	.
cord-350019-4nlbu54e	113	1	During	during	IN
cord-350019-4nlbu54e	113	2	active	active	JJ
cord-350019-4nlbu54e	113	3	transcription	transcription	NN
cord-350019-4nlbu54e	113	4	a	a	DT
cord-350019-4nlbu54e	113	5	lncRNA	lncrna	NN
cord-350019-4nlbu54e	113	6	can	can	MD
cord-350019-4nlbu54e	113	7	either	either	CC
cord-350019-4nlbu54e	113	8	undergo	undergo	VB
cord-350019-4nlbu54e	113	9	differential	differential	JJ
cord-350019-4nlbu54e	113	10	splicing	splicing	NN
cord-350019-4nlbu54e	113	11	or	or	CC
cord-350019-4nlbu54e	113	12	utilize	utilize	VB
cord-350019-4nlbu54e	114	1	a	a	DT
cord-350019-4nlbu54e	114	2	new	new	JJ
cord-350019-4nlbu54e	114	3	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	114	4	start	start	NN
cord-350019-4nlbu54e	114	5	site	site	NN
cord-350019-4nlbu54e	114	6	post	post	JJ
cord-350019-4nlbu54e	114	7	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	114	8	stimulation	stimulation	NN
cord-350019-4nlbu54e	114	9	,	,	,
cord-350019-4nlbu54e	114	10	such	such	JJ
cord-350019-4nlbu54e	114	11	as	as	IN
cord-350019-4nlbu54e	114	12	lipopolysaccharides	lipopolysaccharides	NNP
cord-350019-4nlbu54e	114	13	(	(	-LRB-
cord-350019-4nlbu54e	114	14	LPS	LPS	NNP
cord-350019-4nlbu54e	114	15	)	)	-RRB-
cord-350019-4nlbu54e	114	16	.	.	.
cord-350019-4nlbu54e	115	1	Post	post	JJ
cord-350019-4nlbu54e	115	2	-	-	JJ
cord-350019-4nlbu54e	115	3	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	115	4	regulation	regulation	NN
cord-350019-4nlbu54e	115	5	of	of	IN
cord-350019-4nlbu54e	115	6	a	a	DT
cord-350019-4nlbu54e	115	7	lncRNA	lncrna	NN
cord-350019-4nlbu54e	115	8	is	be	VBZ
cord-350019-4nlbu54e	115	9	broken	break	VBN
cord-350019-4nlbu54e	115	10	up	up	RP
cord-350019-4nlbu54e	115	11	into	into	IN
cord-350019-4nlbu54e	115	12	three	three	CD
cord-350019-4nlbu54e	115	13	parts	part	NNS
cord-350019-4nlbu54e	115	14	:	:	:
cord-350019-4nlbu54e	115	15	IV	IV	NNP
cord-350019-4nlbu54e	115	16	,	,	,
cord-350019-4nlbu54e	115	17	V	v	NN
cord-350019-4nlbu54e	115	18	and	and	CC
cord-350019-4nlbu54e	115	19	VI	VI	NNP
cord-350019-4nlbu54e	115	20	.	.	.
cord-350019-4nlbu54e	116	1	After	after	IN
cord-350019-4nlbu54e	116	2	transcription	transcription	NN
cord-350019-4nlbu54e	116	3	is	be	VBZ
cord-350019-4nlbu54e	116	4	completed	complete	VBN
cord-350019-4nlbu54e	116	5	there	there	EX
cord-350019-4nlbu54e	116	6	is	be	VBZ
cord-350019-4nlbu54e	116	7	several	several	JJ
cord-350019-4nlbu54e	116	8	processes	process	NNS
cord-350019-4nlbu54e	116	9	that	that	WDT
cord-350019-4nlbu54e	116	10	a	a	DT
cord-350019-4nlbu54e	116	11	lncRNA	lncrna	NN
cord-350019-4nlbu54e	116	12	can	can	MD
cord-350019-4nlbu54e	116	13	undergo	undergo	VB
cord-350019-4nlbu54e	116	14	.	.	.
cord-350019-4nlbu54e	117	1	Part	Part	NNP
cord-350019-4nlbu54e	117	2	IV	IV	NNP
cord-350019-4nlbu54e	117	3	depicts	depict	VBZ
cord-350019-4nlbu54e	117	4	RNA	RNA	NNP
cord-350019-4nlbu54e	117	5	modifications	modification	NNS
cord-350019-4nlbu54e	117	6	,	,	,
cord-350019-4nlbu54e	117	7	which	which	WDT
cord-350019-4nlbu54e	117	8	can	can	MD
cord-350019-4nlbu54e	117	9	change	change	VB
cord-350019-4nlbu54e	117	10	the	the	DT
cord-350019-4nlbu54e	117	11	structure	structure	NN
cord-350019-4nlbu54e	117	12	of	of	IN
cord-350019-4nlbu54e	117	13	a	a	DT
cord-350019-4nlbu54e	117	14	lncRNA	lncrna	NN
cord-350019-4nlbu54e	117	15	molecule	molecule	NN
cord-350019-4nlbu54e	117	16	.	.	.
cord-350019-4nlbu54e	118	1	These	these	DT
cord-350019-4nlbu54e	118	2	modifications	modification	NNS
cord-350019-4nlbu54e	118	3	can	can	MD
cord-350019-4nlbu54e	118	4	be	be	VB
cord-350019-4nlbu54e	118	5	added	add	VBN
cord-350019-4nlbu54e	118	6	or	or	CC
cord-350019-4nlbu54e	118	7	removed	remove	VBN
cord-350019-4nlbu54e	118	8	depending	depend	VBG
cord-350019-4nlbu54e	118	9	on	on	IN
cord-350019-4nlbu54e	118	10	the	the	DT
cord-350019-4nlbu54e	118	11	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	118	12	state	state	NN
cord-350019-4nlbu54e	118	13	of	of	IN
cord-350019-4nlbu54e	118	14	a	a	DT
cord-350019-4nlbu54e	118	15	cell	cell	NN
cord-350019-4nlbu54e	118	16	.	.	.
cord-350019-4nlbu54e	119	1	Part	part	NN
cord-350019-4nlbu54e	119	2	V	V	NNP
cord-350019-4nlbu54e	119	3	depicts	depict	VBZ
cord-350019-4nlbu54e	119	4	the	the	DT
cord-350019-4nlbu54e	119	5	process	process	NN
cord-350019-4nlbu54e	119	6	of	of	IN
cord-350019-4nlbu54e	119	7	miRNA	miRNA	NNP
cord-350019-4nlbu54e	119	8	biogenesis	biogenesis	NN
cord-350019-4nlbu54e	119	9	,	,	,
cord-350019-4nlbu54e	119	10	where	where	WRB
cord-350019-4nlbu54e	119	11	a	a	DT
cord-350019-4nlbu54e	119	12	lncRNA	lncrna	NN
cord-350019-4nlbu54e	119	13	can	can	MD
cord-350019-4nlbu54e	119	14	be	be	VB
cord-350019-4nlbu54e	119	15	processed	process	VBN
cord-350019-4nlbu54e	119	16	to	to	IN
cord-350019-4nlbu54e	119	17	a	a	DT
cord-350019-4nlbu54e	119	18	mature	mature	JJ
cord-350019-4nlbu54e	119	19	miRNA	miRNA	NNP
cord-350019-4nlbu54e	119	20	.	.	.
cord-350019-4nlbu54e	120	1	Part	part	NN
cord-350019-4nlbu54e	120	2	VI	VI	NNP
cord-350019-4nlbu54e	120	3	shows	show	VBZ
cord-350019-4nlbu54e	120	4	that	that	IN
cord-350019-4nlbu54e	120	5	a	a	DT
cord-350019-4nlbu54e	120	6	lncRNA	lncrna	NN
cord-350019-4nlbu54e	120	7	can	can	MD
cord-350019-4nlbu54e	120	8	also	also	RB
cord-350019-4nlbu54e	120	9	be	be	VB
cord-350019-4nlbu54e	120	10	translated	translate	VBN
cord-350019-4nlbu54e	120	11	if	if	IN
cord-350019-4nlbu54e	120	12	it	-PRON-	PRP
cord-350019-4nlbu54e	120	13	has	have	VBZ
cord-350019-4nlbu54e	120	14	a	a	DT
cord-350019-4nlbu54e	120	15	small	small	JJ
cord-350019-4nlbu54e	120	16	open	open	JJ
cord-350019-4nlbu54e	120	17	reading	reading	NN
cord-350019-4nlbu54e	120	18	frame	frame	NN
cord-350019-4nlbu54e	120	19	(	(	-LRB-
cord-350019-4nlbu54e	120	20	smORF	smorf	RB
cord-350019-4nlbu54e	120	21	)	)	-RRB-
cord-350019-4nlbu54e	120	22	.	.	.
cord-350019-4nlbu54e	121	1	(	(	-LRB-
cord-350019-4nlbu54e	121	2	C	C	NNP
cord-350019-4nlbu54e	121	3	)	)	-RRB-
cord-350019-4nlbu54e	122	1	The	the	DT
cord-350019-4nlbu54e	122	2	lower	low	JJR
cord-350019-4nlbu54e	122	3	right	right	JJ
cord-350019-4nlbu54e	122	4	panel	panel	NN
cord-350019-4nlbu54e	122	5	of	of	IN
cord-350019-4nlbu54e	122	6	the	the	DT
cord-350019-4nlbu54e	122	7	figure	figure	NN
cord-350019-4nlbu54e	122	8	illustrates	illustrate	VBZ
cord-350019-4nlbu54e	122	9	the	the	DT
cord-350019-4nlbu54e	122	10	regulatory	regulatory	JJ
cord-350019-4nlbu54e	122	11	function	function	NN
cord-350019-4nlbu54e	122	12	of	of	IN
cord-350019-4nlbu54e	122	13	a	a	DT
cord-350019-4nlbu54e	122	14	lncRNA	lncrna	NN
cord-350019-4nlbu54e	122	15	in	in	IN
cord-350019-4nlbu54e	122	16	the	the	DT
cord-350019-4nlbu54e	122	17	nucleus	nucleus	NN
cord-350019-4nlbu54e	122	18	and	and	CC
cord-350019-4nlbu54e	122	19	the	the	DT
cord-350019-4nlbu54e	122	20	cytoplasm	cytoplasm	NN
cord-350019-4nlbu54e	122	21	.	.	.
cord-350019-4nlbu54e	123	1	During	during	IN
cord-350019-4nlbu54e	123	2	active	active	JJ
cord-350019-4nlbu54e	123	3	transcription	transcription	NN
cord-350019-4nlbu54e	123	4	(	(	-LRB-
cord-350019-4nlbu54e	123	5	basally	basally	RB
cord-350019-4nlbu54e	123	6	'	'	``
cord-350019-4nlbu54e	123	7	Part	part	NN
cord-350019-4nlbu54e	123	8	I	-PRON-	PRP
cord-350019-4nlbu54e	123	9	'	'	''
cord-350019-4nlbu54e	123	10	or	or	CC
cord-350019-4nlbu54e	123	11	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	123	12	'	'	''
cord-350019-4nlbu54e	123	13	Part	Part	NNP
cord-350019-4nlbu54e	123	14	II	II	NNP
cord-350019-4nlbu54e	123	15	'	'	''
cord-350019-4nlbu54e	123	16	)	)	-RRB-
cord-350019-4nlbu54e	123	17	,	,	,
cord-350019-4nlbu54e	123	18	a	a	DT
cord-350019-4nlbu54e	123	19	lncRNA	lncrna	NN
cord-350019-4nlbu54e	123	20	can	can	MD
cord-350019-4nlbu54e	123	21	function	function	VB
cord-350019-4nlbu54e	123	22	to	to	TO
cord-350019-4nlbu54e	123	23	repress	repress	VB
cord-350019-4nlbu54e	123	24	genes	gene	NNS
cord-350019-4nlbu54e	123	25	(	(	-LRB-
cord-350019-4nlbu54e	123	26	mRNA	mrna	NN
cord-350019-4nlbu54e	123	27	gene	gene	NN
cord-350019-4nlbu54e	123	28	A	A	NNP
cord-350019-4nlbu54e	123	29	and	and	CC
cord-350019-4nlbu54e	123	30	C	C	NNP
cord-350019-4nlbu54e	123	31	)	)	-RRB-
cord-350019-4nlbu54e	123	32	or	or	CC
cord-350019-4nlbu54e	123	33	activate	activate	VB
cord-350019-4nlbu54e	123	34	genes	gene	NNS
cord-350019-4nlbu54e	123	35	(	(	-LRB-
cord-350019-4nlbu54e	123	36	mRNA	mRNA	NNP
cord-350019-4nlbu54e	123	37	gene	gene	NN
cord-350019-4nlbu54e	123	38	A	A	NNP
cord-350019-4nlbu54e	123	39	and	and	CC
cord-350019-4nlbu54e	123	40	B	b	NN
cord-350019-4nlbu54e	123	41	)	)	-RRB-
cord-350019-4nlbu54e	123	42	.	.	.
cord-350019-4nlbu54e	124	1	A	a	DT
cord-350019-4nlbu54e	124	2	lncRNA	lncrna	NN
cord-350019-4nlbu54e	124	3	can	can	MD
cord-350019-4nlbu54e	124	4	either	either	CC
cord-350019-4nlbu54e	124	5	be	be	VB
cord-350019-4nlbu54e	124	6	a	a	DT
cord-350019-4nlbu54e	124	7	scaffold	scaffold	NN
cord-350019-4nlbu54e	124	8	for	for	IN
cord-350019-4nlbu54e	124	9	transcription	transcription	NN
cord-350019-4nlbu54e	124	10	factors	factor	NNS
cord-350019-4nlbu54e	124	11	to	to	TO
cord-350019-4nlbu54e	124	12	enhance	enhance	VB
cord-350019-4nlbu54e	124	13	activation	activation	NN
cord-350019-4nlbu54e	124	14	,	,	,
cord-350019-4nlbu54e	124	15	or	or	CC
cord-350019-4nlbu54e	124	16	a	a	DT
cord-350019-4nlbu54e	124	17	scaffold	scaffold	NN
cord-350019-4nlbu54e	124	18	for	for	IN
cord-350019-4nlbu54e	124	19	chromatin	chromatin	NN
cord-350019-4nlbu54e	124	20	remodeler	remodeler	NN
cord-350019-4nlbu54e	124	21	proteins	protein	NNS
cord-350019-4nlbu54e	124	22	to	to	TO
cord-350019-4nlbu54e	124	23	open	open	VB
cord-350019-4nlbu54e	124	24	or	or	CC
cord-350019-4nlbu54e	124	25	close	close	JJ
cord-350019-4nlbu54e	124	26	chromatin	chromatin	NN
cord-350019-4nlbu54e	124	27	.	.	.
cord-350019-4nlbu54e	125	1	A	a	DT
cord-350019-4nlbu54e	125	2	lncRNA	lncrna	NN
cord-350019-4nlbu54e	125	3	can	can	MD
cord-350019-4nlbu54e	125	4	also	also	RB
cord-350019-4nlbu54e	125	5	regulate	regulate	VB
cord-350019-4nlbu54e	125	6	a	a	DT
cord-350019-4nlbu54e	125	7	mRNA	mRNA	NNP
cord-350019-4nlbu54e	125	8	transcript	transcript	NN
cord-350019-4nlbu54e	125	9	co	co	NN
cord-350019-4nlbu54e	125	10	-	-	NN
cord-350019-4nlbu54e	125	11	transcriptionally	transcriptionally	RB
cord-350019-4nlbu54e	125	12	'	'	''
cord-350019-4nlbu54e	125	13	Part	Part	NNP
cord-350019-4nlbu54e	125	14	III	III	NNP
cord-350019-4nlbu54e	125	15	'	'	''
cord-350019-4nlbu54e	125	16	by	by	IN
cord-350019-4nlbu54e	125	17	affecting	affect	VBG
cord-350019-4nlbu54e	125	18	either	either	CC
cord-350019-4nlbu54e	125	19	the	the	DT
cord-350019-4nlbu54e	125	20	stability	stability	NN
cord-350019-4nlbu54e	125	21	,	,	,
cord-350019-4nlbu54e	125	22	change	change	VB
cord-350019-4nlbu54e	125	23	the	the	DT
cord-350019-4nlbu54e	125	24	splicing	splicing	NN
cord-350019-4nlbu54e	125	25	activity	activity	NN
cord-350019-4nlbu54e	125	26	,	,	,
cord-350019-4nlbu54e	125	27	editing	editing	NN
cord-350019-4nlbu54e	125	28	of	of	IN
cord-350019-4nlbu54e	125	29	modifications	modification	NNS
cord-350019-4nlbu54e	125	30	,	,	,
cord-350019-4nlbu54e	125	31	or	or	CC
cord-350019-4nlbu54e	125	32	even	even	RB
cord-350019-4nlbu54e	125	33	the	the	DT
cord-350019-4nlbu54e	125	34	capping	capping	NN
cord-350019-4nlbu54e	125	35	of	of	IN
cord-350019-4nlbu54e	125	36	the	the	DT
cord-350019-4nlbu54e	125	37	mature	mature	JJ
cord-350019-4nlbu54e	125	38	mRNA	mrna	NN
cord-350019-4nlbu54e	125	39	.	.	.
cord-350019-4nlbu54e	126	1	Finally	finally	RB
cord-350019-4nlbu54e	126	2	,	,	,
cord-350019-4nlbu54e	126	3	post	post	VB
cord-350019-4nlbu54e	126	4	-	-	JJ
cord-350019-4nlbu54e	126	5	transcriptionally	transcriptionally	RB
cord-350019-4nlbu54e	126	6	a	a	DT
cord-350019-4nlbu54e	126	7	lncRNA	lncrna	NN
cord-350019-4nlbu54e	126	8	can	can	MD
cord-350019-4nlbu54e	126	9	function	function	VB
cord-350019-4nlbu54e	126	10	to	to	TO
cord-350019-4nlbu54e	126	11	regulate	regulate	VB
cord-350019-4nlbu54e	126	12	the	the	DT
cord-350019-4nlbu54e	126	13	mRNA	mrna	NN
cord-350019-4nlbu54e	126	14	in	in	IN
cord-350019-4nlbu54e	126	15	several	several	JJ
cord-350019-4nlbu54e	126	16	ways	way	NNS
cord-350019-4nlbu54e	126	17	.	.	.
cord-350019-4nlbu54e	127	1	A	a	DT
cord-350019-4nlbu54e	127	2	lncRNA	lncrna	NN
cord-350019-4nlbu54e	127	3	can	can	MD
cord-350019-4nlbu54e	127	4	affect	affect	VB
cord-350019-4nlbu54e	127	5	the	the	DT
cord-350019-4nlbu54e	127	6	stability	stability	NN
cord-350019-4nlbu54e	127	7	of	of	IN
cord-350019-4nlbu54e	127	8	a	a	DT
cord-350019-4nlbu54e	127	9	mRNA	mRNA	NNP
cord-350019-4nlbu54e	127	10	transcript	transcript	NN
cord-350019-4nlbu54e	127	11	:	:	:
cord-350019-4nlbu54e	127	12	'	'	``
cord-350019-4nlbu54e	127	13	Part	Part	NNP
cord-350019-4nlbu54e	127	14	IV	IV	NNP
cord-350019-4nlbu54e	127	15	and	and	CC
cord-350019-4nlbu54e	127	16	Part	Part	NNP
cord-350019-4nlbu54e	127	17	V.	V.	NNP
cord-350019-4nlbu54e	127	18	'	'	''
cord-350019-4nlbu54e	128	1	Alternatively	alternatively	RB
cord-350019-4nlbu54e	128	2	,	,	,
cord-350019-4nlbu54e	128	3	a	a	DT
cord-350019-4nlbu54e	128	4	lncRNA	lncrna	NN
cord-350019-4nlbu54e	128	5	can	can	MD
cord-350019-4nlbu54e	128	6	function	function	VB
cord-350019-4nlbu54e	128	7	as	as	IN
cord-350019-4nlbu54e	128	8	a	a	DT
cord-350019-4nlbu54e	128	9	miRNA	miRNA	NNP
cord-350019-4nlbu54e	128	10	sponge	sponge	NN
cord-350019-4nlbu54e	128	11	which	which	WDT
cord-350019-4nlbu54e	128	12	indirectly	indirectly	RB
cord-350019-4nlbu54e	128	13	de	de	VBD
cord-350019-4nlbu54e	128	14	-	-	NN
cord-350019-4nlbu54e	128	15	represses	repress	VBZ
cord-350019-4nlbu54e	128	16	the	the	DT
cord-350019-4nlbu54e	128	17	expression	expression	NN
cord-350019-4nlbu54e	128	18	of	of	IN
cord-350019-4nlbu54e	128	19	a	a	DT
cord-350019-4nlbu54e	128	20	mRNA	mrna	NN
cord-350019-4nlbu54e	128	21	that	that	WDT
cord-350019-4nlbu54e	128	22	would	would	MD
cord-350019-4nlbu54e	128	23	be	be	VB
cord-350019-4nlbu54e	128	24	targeted	target	VBN
cord-350019-4nlbu54e	128	25	by	by	IN
cord-350019-4nlbu54e	128	26	the	the	DT
cord-350019-4nlbu54e	128	27	miRNAs	miRNAs	NNP
cord-350019-4nlbu54e	128	28	.	.	.
cord-350019-4nlbu54e	129	1	Lastly	lastly	RB
cord-350019-4nlbu54e	129	2	,	,	,
cord-350019-4nlbu54e	129	3	a	a	DT
cord-350019-4nlbu54e	129	4	lncRNA	lncrna	NN
cord-350019-4nlbu54e	129	5	can	can	MD
cord-350019-4nlbu54e	129	6	modulate	modulate	VB
cord-350019-4nlbu54e	129	7	the	the	DT
cord-350019-4nlbu54e	129	8	translation	translation	NN
cord-350019-4nlbu54e	129	9	of	of	IN
cord-350019-4nlbu54e	129	10	a	a	DT
cord-350019-4nlbu54e	129	11	mRNA	mrna	NN
cord-350019-4nlbu54e	129	12	by	by	IN
cord-350019-4nlbu54e	129	13	binding	bind	VBG
cord-350019-4nlbu54e	129	14	to	to	IN
cord-350019-4nlbu54e	129	15	ribosomes	ribosome	NNS
cord-350019-4nlbu54e	129	16	or	or	CC
cord-350019-4nlbu54e	129	17	mRNA	mrna	NN
cord-350019-4nlbu54e	129	18	transcripts	transcript	NNS
cord-350019-4nlbu54e	129	19	during	during	IN
cord-350019-4nlbu54e	129	20	translation	translation	NN
cord-350019-4nlbu54e	129	21	.	.	.
cord-350019-4nlbu54e	130	1	Genome	genome	NN
cord-350019-4nlbu54e	130	2	-	-	HYPH
cord-350019-4nlbu54e	130	3	wide	wide	JJ
cord-350019-4nlbu54e	130	4	association	association	NN
cord-350019-4nlbu54e	130	5	studies	study	NNS
cord-350019-4nlbu54e	130	6	(	(	-LRB-
cord-350019-4nlbu54e	130	7	GWAS	GWAS	NNP
cord-350019-4nlbu54e	130	8	)	)	-RRB-
cord-350019-4nlbu54e	130	9	have	have	VBP
cord-350019-4nlbu54e	130	10	revolutionized	revolutionize	VBN
cord-350019-4nlbu54e	130	11	the	the	DT
cord-350019-4nlbu54e	130	12	study	study	NN
cord-350019-4nlbu54e	130	13	of	of	IN
cord-350019-4nlbu54e	130	14	complex	complex	JJ
cord-350019-4nlbu54e	130	15	diseases	disease	NNS
cord-350019-4nlbu54e	130	16	by	by	IN
cord-350019-4nlbu54e	130	17	allowing	allow	VBG
cord-350019-4nlbu54e	130	18	quantitative	quantitative	JJ
cord-350019-4nlbu54e	130	19	disease	disease	NN
cord-350019-4nlbu54e	130	20	-	-	HYPH
cord-350019-4nlbu54e	130	21	association	association	NN
cord-350019-4nlbu54e	130	22	of	of	IN
cord-350019-4nlbu54e	130	23	thousands	thousand	NNS
cord-350019-4nlbu54e	130	24	of	of	IN
cord-350019-4nlbu54e	130	25	genetic	genetic	JJ
cord-350019-4nlbu54e	130	26	loci	locus	NNS
cord-350019-4nlbu54e	130	27	[	[	-LRB-
cord-350019-4nlbu54e	130	28	103	103	CD
cord-350019-4nlbu54e	130	29	]	]	-RRB-
cord-350019-4nlbu54e	130	30	.	.	.
cord-350019-4nlbu54e	131	1	These	these	DT
cord-350019-4nlbu54e	131	2	studies	study	NNS
cord-350019-4nlbu54e	131	3	include	include	VBP
cord-350019-4nlbu54e	131	4	evaluation	evaluation	NN
cord-350019-4nlbu54e	131	5	of	of	IN
cord-350019-4nlbu54e	131	6	single	single	JJ
cord-350019-4nlbu54e	131	7	-	-	HYPH
cord-350019-4nlbu54e	131	8	nucleotide	nucleotide	NN
cord-350019-4nlbu54e	131	9	polymorphisms	polymorphism	NNS
cord-350019-4nlbu54e	131	10	(	(	-LRB-
cord-350019-4nlbu54e	131	11	SNPs	SNPs	NNP
cord-350019-4nlbu54e	131	12	)	)	-RRB-
cord-350019-4nlbu54e	131	13	or	or	CC
cord-350019-4nlbu54e	131	14	deletions	deletion	NNS
cord-350019-4nlbu54e	131	15	and	and	CC
cord-350019-4nlbu54e	131	16	determination	determination	NN
cord-350019-4nlbu54e	131	17	of	of	IN
cord-350019-4nlbu54e	131	18	their	-PRON-	PRP$
cord-350019-4nlbu54e	131	19	association	association	NN
cord-350019-4nlbu54e	131	20	with	with	IN
cord-350019-4nlbu54e	131	21	a	a	DT
cord-350019-4nlbu54e	131	22	disease	disease	NN
cord-350019-4nlbu54e	131	23	phenotype	phenotype	NN
cord-350019-4nlbu54e	131	24	.	.	.
cord-350019-4nlbu54e	132	1	Diseases	disease	NNS
cord-350019-4nlbu54e	132	2	studied	study	VBD
cord-350019-4nlbu54e	132	3	range	range	VBP
cord-350019-4nlbu54e	132	4	from	from	IN
cord-350019-4nlbu54e	132	5	Inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	132	6	Bowel	Bowel	NNP
cord-350019-4nlbu54e	132	7	Disease	Disease	NNP
cord-350019-4nlbu54e	132	8	(	(	-LRB-
cord-350019-4nlbu54e	132	9	IDB	IDB	NNP
cord-350019-4nlbu54e	132	10	)	)	-RRB-
cord-350019-4nlbu54e	132	11	to	to	IN
cord-350019-4nlbu54e	132	12	schizophrenia	schizophrenia	NN
cord-350019-4nlbu54e	132	13	[	[	-LRB-
cord-350019-4nlbu54e	132	14	104	104	CD
cord-350019-4nlbu54e	132	15	,	,	,
cord-350019-4nlbu54e	132	16	105	105	CD
cord-350019-4nlbu54e	132	17	]	]	-RRB-
cord-350019-4nlbu54e	132	18	.	.	.
cord-350019-4nlbu54e	133	1	Until	until	IN
cord-350019-4nlbu54e	133	2	recently	recently	RB
cord-350019-4nlbu54e	133	3	,	,	,
cord-350019-4nlbu54e	133	4	most	most	JJS
cord-350019-4nlbu54e	133	5	GWAS	GWAS	NNP
cord-350019-4nlbu54e	133	6	studies	study	NNS
cord-350019-4nlbu54e	133	7	focused	focus	VBD
cord-350019-4nlbu54e	133	8	on	on	IN
cord-350019-4nlbu54e	133	9	proteincoding	proteincode	VBG
cord-350019-4nlbu54e	133	10	genes	gene	NNS
cord-350019-4nlbu54e	133	11	,	,	,
cord-350019-4nlbu54e	133	12	even	even	RB
cord-350019-4nlbu54e	133	13	though	though	IN
cord-350019-4nlbu54e	133	14	90	90	CD
cord-350019-4nlbu54e	133	15	%	%	NN
cord-350019-4nlbu54e	133	16	of	of	IN
cord-350019-4nlbu54e	133	17	disease	disease	NN
cord-350019-4nlbu54e	133	18	-	-	HYPH
cord-350019-4nlbu54e	133	19	associated	associate	VBN
cord-350019-4nlbu54e	133	20	SNPs	SNPs	NNPS
cord-350019-4nlbu54e	133	21	lie	lie	VBP
cord-350019-4nlbu54e	133	22	in	in	IN
cord-350019-4nlbu54e	133	23	noncoding	noncoding	JJ
cord-350019-4nlbu54e	133	24	regions	region	NNS
cord-350019-4nlbu54e	133	25	of	of	IN
cord-350019-4nlbu54e	133	26	the	the	DT
cord-350019-4nlbu54e	133	27	genome	genome	NN
cord-350019-4nlbu54e	133	28	[	[	-LRB-
cord-350019-4nlbu54e	133	29	106	106	CD
cord-350019-4nlbu54e	133	30	]	]	-RRB-
cord-350019-4nlbu54e	133	31	.	.	.
cord-350019-4nlbu54e	134	1	There	there	EX
cord-350019-4nlbu54e	134	2	are	be	VBP
cord-350019-4nlbu54e	134	3	several	several	JJ
cord-350019-4nlbu54e	134	4	databases	database	NNS
cord-350019-4nlbu54e	134	5	that	that	WDT
cord-350019-4nlbu54e	134	6	summarize	summarize	VBP
cord-350019-4nlbu54e	134	7	the	the	DT
cord-350019-4nlbu54e	134	8	plethora	plethora	NN
cord-350019-4nlbu54e	134	9	of	of	IN
cord-350019-4nlbu54e	134	10	published	publish	VBN
cord-350019-4nlbu54e	134	11	human	human	JJ
cord-350019-4nlbu54e	134	12	sequencing	sequencing	NN
cord-350019-4nlbu54e	134	13	studies	study	NNS
cord-350019-4nlbu54e	134	14	,	,	,
cord-350019-4nlbu54e	134	15	including	include	VBG
cord-350019-4nlbu54e	134	16	UK	UK	NNP
cord-350019-4nlbu54e	134	17	Biobank	Biobank	NNP
cord-350019-4nlbu54e	134	18	[	[	-LRB-
cord-350019-4nlbu54e	134	19	107	107	CD
cord-350019-4nlbu54e	134	20	]	]	-RRB-
cord-350019-4nlbu54e	134	21	and	and	CC
cord-350019-4nlbu54e	134	22	GWAS	GWAS	NNP
cord-350019-4nlbu54e	134	23	Catalog	Catalog	NNP
cord-350019-4nlbu54e	134	24	-EMBL	-EMBL	:
cord-350019-4nlbu54e	134	25	-	-	HYPH
cord-350019-4nlbu54e	134	26	EBI	ebi	NN
cord-350019-4nlbu54e	134	27	[	[	-LRB-
cord-350019-4nlbu54e	134	28	108	108	CD
cord-350019-4nlbu54e	134	29	]	]	-RRB-
cord-350019-4nlbu54e	134	30	.	.	.
cord-350019-4nlbu54e	135	1	Other	other	JJ
cord-350019-4nlbu54e	135	2	databases	database	NNS
cord-350019-4nlbu54e	135	3	specifically	specifically	RB
cord-350019-4nlbu54e	135	4	focus	focus	VBP
cord-350019-4nlbu54e	135	5	on	on	IN
cord-350019-4nlbu54e	135	6	SNPs	snp	NNS
cord-350019-4nlbu54e	135	7	within	within	IN
cord-350019-4nlbu54e	135	8	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	135	9	,	,	,
cord-350019-4nlbu54e	135	10	such	such	JJ
cord-350019-4nlbu54e	135	11	as	as	IN
cord-350019-4nlbu54e	135	12	lncRNASNP2	lncRNASNP2	NNP
cord-350019-4nlbu54e	135	13	[	[	-LRB-
cord-350019-4nlbu54e	135	14	109	109	CD
cord-350019-4nlbu54e	135	15	]	]	-RRB-
cord-350019-4nlbu54e	135	16	and	and	CC
cord-350019-4nlbu54e	135	17	Lnc2Catlas	Lnc2Catlas	NNP
cord-350019-4nlbu54e	135	18	[	[	-LRB-
cord-350019-4nlbu54e	135	19	110	110	CD
cord-350019-4nlbu54e	135	20	]	]	-RRB-
cord-350019-4nlbu54e	135	21	.	.	.
cord-350019-4nlbu54e	136	1	To	to	IN
cord-350019-4nlbu54e	136	2	date	date	NN
cord-350019-4nlbu54e	136	3	,	,	,
cord-350019-4nlbu54e	136	4	a	a	DT
cord-350019-4nlbu54e	136	5	couple	couple	NN
cord-350019-4nlbu54e	136	6	of	of	IN
cord-350019-4nlbu54e	136	7	studies	study	NNS
cord-350019-4nlbu54e	136	8	have	have	VBP
cord-350019-4nlbu54e	136	9	clearly	clearly	RB
cord-350019-4nlbu54e	136	10	shown	show	VBN
cord-350019-4nlbu54e	136	11	how	how	WRB
cord-350019-4nlbu54e	136	12	SNPs	snp	NNS
cord-350019-4nlbu54e	136	13	from	from	IN
cord-350019-4nlbu54e	136	14	GWAS	GWAS	NNP
cord-350019-4nlbu54e	136	15	studies	study	NNS
cord-350019-4nlbu54e	136	16	can	can	MD
cord-350019-4nlbu54e	136	17	be	be	VB
cord-350019-4nlbu54e	136	18	used	use	VBN
cord-350019-4nlbu54e	136	19	to	to	TO
cord-350019-4nlbu54e	136	20	identify	identify	VB
cord-350019-4nlbu54e	136	21	clinically	clinically	RB
cord-350019-4nlbu54e	136	22	relevant	relevant	JJ
cord-350019-4nlbu54e	136	23	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	136	24	.	.	.
cord-350019-4nlbu54e	137	1	Castellanos	Castellanos	NNP
cord-350019-4nlbu54e	137	2	-	-	HYPH
cord-350019-4nlbu54e	137	3	Rubio	Rubio	NNP
cord-350019-4nlbu54e	137	4	et	et	NNP
cord-350019-4nlbu54e	137	5	al	al	NNP
cord-350019-4nlbu54e	137	6	.	.	NNP
cord-350019-4nlbu54e	137	7	identified	identify	VBD
cord-350019-4nlbu54e	137	8	a	a	DT
cord-350019-4nlbu54e	137	9	SNP	SNP	NNP
cord-350019-4nlbu54e	137	10	rs917997	rs917997	VBN
cord-350019-4nlbu54e	137	11	associated	associate	VBN
cord-350019-4nlbu54e	137	12	with	with	IN
cord-350019-4nlbu54e	137	13	Celiac	Celiac	NNP
cord-350019-4nlbu54e	137	14	Disease	Disease	NNP
cord-350019-4nlbu54e	137	15	and	and	CC
cord-350019-4nlbu54e	137	16	showed	show	VBD
cord-350019-4nlbu54e	137	17	it	-PRON-	PRP
cord-350019-4nlbu54e	137	18	was	be	VBD
cord-350019-4nlbu54e	137	19	located	locate	VBN
cord-350019-4nlbu54e	137	20	within	within	IN
cord-350019-4nlbu54e	137	21	a	a	DT
cord-350019-4nlbu54e	137	22	novel	novel	NN
cord-350019-4nlbu54e	137	23	lncRNA	lncrna	NN
cord-350019-4nlbu54e	137	24	,	,	,
cord-350019-4nlbu54e	137	25	Lnc13	Lnc13	NNP
cord-350019-4nlbu54e	137	26	[	[	-LRB-
cord-350019-4nlbu54e	137	27	62	62	CD
cord-350019-4nlbu54e	137	28	]	]	-RRB-
cord-350019-4nlbu54e	137	29	.	.	.
cord-350019-4nlbu54e	138	1	Lnc13	Lnc13	NNP
cord-350019-4nlbu54e	138	2	regulates	regulate	VBZ
cord-350019-4nlbu54e	138	3	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	138	4	genes	gene	NNS
cord-350019-4nlbu54e	138	5	and	and	CC
cord-350019-4nlbu54e	138	6	mediates	mediate	VBZ
cord-350019-4nlbu54e	138	7	its	-PRON-	PRP$
cord-350019-4nlbu54e	138	8	function	function	NN
cord-350019-4nlbu54e	138	9	via	via	IN
cord-350019-4nlbu54e	138	10	an	an	DT
cord-350019-4nlbu54e	138	11	interaction	interaction	NN
cord-350019-4nlbu54e	138	12	with	with	IN
cord-350019-4nlbu54e	138	13	an	an	DT
cord-350019-4nlbu54e	138	14	hnRNP	hnrnp	DT
cord-350019-4nlbu54e	138	15	protein	protein	NN
cord-350019-4nlbu54e	138	16	[	[	-LRB-
cord-350019-4nlbu54e	138	17	62	62	CD
cord-350019-4nlbu54e	138	18	]	]	-RRB-
cord-350019-4nlbu54e	138	19	.	.	.
cord-350019-4nlbu54e	139	1	Furthermore	furthermore	RB
cord-350019-4nlbu54e	139	2	,	,	,
cord-350019-4nlbu54e	139	3	they	-PRON-	PRP
cord-350019-4nlbu54e	139	4	showed	show	VBD
cord-350019-4nlbu54e	139	5	that	that	IN
cord-350019-4nlbu54e	139	6	the	the	DT
cord-350019-4nlbu54e	139	7	SNP	SNP	NNP
cord-350019-4nlbu54e	139	8	disrupted	disrupt	VBD
cord-350019-4nlbu54e	139	9	the	the	DT
cord-350019-4nlbu54e	139	10	RNA	rna	NN
cord-350019-4nlbu54e	139	11	-	-	HYPH
cord-350019-4nlbu54e	139	12	protein	protein	NN
cord-350019-4nlbu54e	139	13	interaction	interaction	NN
cord-350019-4nlbu54e	139	14	,	,	,
cord-350019-4nlbu54e	139	15	thus	thus	RB
cord-350019-4nlbu54e	139	16	making	make	VBG
cord-350019-4nlbu54e	139	17	the	the	DT
cord-350019-4nlbu54e	139	18	lncRNA	lncrna	NN
cord-350019-4nlbu54e	139	19	dysfunctional	dysfunctional	JJ
cord-350019-4nlbu54e	139	20	[	[	-LRB-
cord-350019-4nlbu54e	139	21	62	62	CD
cord-350019-4nlbu54e	139	22	]	]	-RRB-
cord-350019-4nlbu54e	139	23	.	.	.
cord-350019-4nlbu54e	140	1	Another	another	DT
cord-350019-4nlbu54e	140	2	fascinating	fascinating	JJ
cord-350019-4nlbu54e	140	3	study	study	NN
cord-350019-4nlbu54e	140	4	began	begin	VBD
cord-350019-4nlbu54e	140	5	by	by	IN
cord-350019-4nlbu54e	140	6	mining	mine	VBG
cord-350019-4nlbu54e	140	7	GWAS	GWAS	NNP
cord-350019-4nlbu54e	140	8	for	for	IN
cord-350019-4nlbu54e	140	9	atherosclerosis	atherosclerosis	NN
cord-350019-4nlbu54e	140	10	disease	disease	NN
cord-350019-4nlbu54e	140	11	-	-	HYPH
cord-350019-4nlbu54e	140	12	associated	associate	VBN
cord-350019-4nlbu54e	140	13	SNPs	SNPs	NNPS
cord-350019-4nlbu54e	140	14	,	,	,
cord-350019-4nlbu54e	140	15	which	which	WDT
cord-350019-4nlbu54e	140	16	led	lead	VBD
cord-350019-4nlbu54e	140	17	to	to	IN
cord-350019-4nlbu54e	140	18	the	the	DT
cord-350019-4nlbu54e	140	19	discovery	discovery	NN
cord-350019-4nlbu54e	140	20	of	of	IN
cord-350019-4nlbu54e	140	21	a	a	DT
cord-350019-4nlbu54e	140	22	novel	novel	NN
cord-350019-4nlbu54e	140	23	lncRNA	lncrna	NN
cord-350019-4nlbu54e	140	24	,	,	,
cord-350019-4nlbu54e	140	25	LIN00305	LIN00305	NNP
cord-350019-4nlbu54e	140	26	,	,	,
cord-350019-4nlbu54e	140	27	that	that	WDT
cord-350019-4nlbu54e	140	28	had	have	VBD
cord-350019-4nlbu54e	140	29	5	5	CD
cord-350019-4nlbu54e	140	30	SNPs	snp	NNS
cord-350019-4nlbu54e	140	31	that	that	WDT
cord-350019-4nlbu54e	140	32	were	be	VBD
cord-350019-4nlbu54e	140	33	associated	associate	VBN
cord-350019-4nlbu54e	140	34	with	with	IN
cord-350019-4nlbu54e	140	35	atherosclerosis	atherosclerosis	NN
cord-350019-4nlbu54e	140	36	all	all	DT
cord-350019-4nlbu54e	140	37	located	locate	VBN
cord-350019-4nlbu54e	140	38	within	within	IN
cord-350019-4nlbu54e	140	39	an	an	DT
cord-350019-4nlbu54e	140	40	intronic	intronic	JJ
cord-350019-4nlbu54e	140	41	region	region	NN
cord-350019-4nlbu54e	140	42	[	[	-LRB-
cord-350019-4nlbu54e	140	43	111	111	CD
cord-350019-4nlbu54e	140	44	]	]	-RRB-
cord-350019-4nlbu54e	140	45	.	.	.
cord-350019-4nlbu54e	141	1	The	the	DT
cord-350019-4nlbu54e	141	2	group	group	NN
cord-350019-4nlbu54e	141	3	went	go	VBD
cord-350019-4nlbu54e	141	4	on	on	RP
cord-350019-4nlbu54e	141	5	to	to	TO
cord-350019-4nlbu54e	141	6	characterize	characterize	VB
cord-350019-4nlbu54e	141	7	LINC00305	LINC00305	NNP
cord-350019-4nlbu54e	141	8	in	in	IN
cord-350019-4nlbu54e	141	9	human	human	JJ
cord-350019-4nlbu54e	141	10	primary	primary	NN
cord-350019-4nlbu54e	141	11	and	and	CC
cord-350019-4nlbu54e	141	12	immortalized	immortalize	VBN
cord-350019-4nlbu54e	141	13	monocytes	monocyte	NNS
cord-350019-4nlbu54e	141	14	as	as	IN
cord-350019-4nlbu54e	141	15	a	a	DT
cord-350019-4nlbu54e	141	16	promoter	promoter	NN
cord-350019-4nlbu54e	141	17	of	of	IN
cord-350019-4nlbu54e	141	18	inflammation	inflammation	NN
cord-350019-4nlbu54e	141	19	through	through	IN
cord-350019-4nlbu54e	141	20	activating	activate	VBG
cord-350019-4nlbu54e	141	21	the	the	DT
cord-350019-4nlbu54e	141	22	aryl	aryl	NN
cord-350019-4nlbu54e	141	23	-	-	HYPH
cord-350019-4nlbu54e	141	24	hydrocarbon	hydrocarbon	NN
cord-350019-4nlbu54e	141	25	receptor	receptor	NN
cord-350019-4nlbu54e	141	26	repressor	repressor	NN
cord-350019-4nlbu54e	141	27	(	(	-LRB-
cord-350019-4nlbu54e	141	28	AHRR	AHRR	NNP
cord-350019-4nlbu54e	141	29	)	)	-RRB-
cord-350019-4nlbu54e	142	1	-NF	-NF	,
cord-350019-4nlbu54e	142	2	-	-	:
cord-350019-4nlbu54e	142	3	κB	κB	NNP
cord-350019-4nlbu54e	142	4	pathway	pathway	NN
cord-350019-4nlbu54e	142	5	by	by	IN
cord-350019-4nlbu54e	142	6	directly	directly	RB
cord-350019-4nlbu54e	142	7	binding	bind	VBG
cord-350019-4nlbu54e	142	8	to	to	IN
cord-350019-4nlbu54e	142	9	lipocalin-1	lipocalin-1	NNP
cord-350019-4nlbu54e	142	10	interacting	interact	VBG
cord-350019-4nlbu54e	142	11	membrane	membrane	NN
cord-350019-4nlbu54e	142	12	receptor	receptor	NN
cord-350019-4nlbu54e	142	13	(	(	-LRB-
cord-350019-4nlbu54e	142	14	LIMR	LIMR	NNP
cord-350019-4nlbu54e	142	15	)	)	-RRB-
cord-350019-4nlbu54e	142	16	,	,	,
cord-350019-4nlbu54e	142	17	acting	act	VBG
cord-350019-4nlbu54e	142	18	as	as	IN
cord-350019-4nlbu54e	142	19	a	a	DT
cord-350019-4nlbu54e	142	20	scaffold	scaffold	NN
cord-350019-4nlbu54e	142	21	to	to	TO
cord-350019-4nlbu54e	142	22	promote	promote	VB
cord-350019-4nlbu54e	142	23	the	the	DT
cord-350019-4nlbu54e	142	24	interaction	interaction	NN
cord-350019-4nlbu54e	142	25	between	between	IN
cord-350019-4nlbu54e	142	26	LIMR	LIMR	NNP
cord-350019-4nlbu54e	142	27	and	and	CC
cord-350019-4nlbu54e	142	28	AHRR	AHRR	NNP
cord-350019-4nlbu54e	142	29	[	[	-LRB-
cord-350019-4nlbu54e	142	30	111	111	CD
cord-350019-4nlbu54e	142	31	]	]	-RRB-
cord-350019-4nlbu54e	142	32	.	.	.
cord-350019-4nlbu54e	143	1	Both	both	DT
cord-350019-4nlbu54e	143	2	of	of	IN
cord-350019-4nlbu54e	143	3	these	these	DT
cord-350019-4nlbu54e	143	4	studies	study	NNS
cord-350019-4nlbu54e	143	5	started	start	VBD
cord-350019-4nlbu54e	143	6	by	by	IN
cord-350019-4nlbu54e	143	7	investigating	investigate	VBG
cord-350019-4nlbu54e	143	8	clinically	clinically	RB
cord-350019-4nlbu54e	143	9	relevant	relevant	JJ
cord-350019-4nlbu54e	143	10	SNPs	snp	NNS
cord-350019-4nlbu54e	143	11	that	that	WDT
cord-350019-4nlbu54e	143	12	led	lead	VBD
cord-350019-4nlbu54e	143	13	to	to	IN
cord-350019-4nlbu54e	143	14	the	the	DT
cord-350019-4nlbu54e	143	15	discovery	discovery	NN
cord-350019-4nlbu54e	143	16	of	of	IN
cord-350019-4nlbu54e	143	17	disease	disease	NN
cord-350019-4nlbu54e	143	18	-	-	HYPH
cord-350019-4nlbu54e	143	19	associated	associate	VBN
cord-350019-4nlbu54e	143	20	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	143	21	,	,	,
cord-350019-4nlbu54e	143	22	providing	provide	VBG
cord-350019-4nlbu54e	143	23	the	the	DT
cord-350019-4nlbu54e	143	24	groundwork	groundwork	NN
cord-350019-4nlbu54e	143	25	for	for	IN
cord-350019-4nlbu54e	143	26	future	future	JJ
cord-350019-4nlbu54e	143	27	studies	study	NNS
cord-350019-4nlbu54e	143	28	on	on	IN
cord-350019-4nlbu54e	143	29	potential	potential	JJ
cord-350019-4nlbu54e	143	30	biomarkers	biomarker	NNS
cord-350019-4nlbu54e	143	31	or	or	CC
cord-350019-4nlbu54e	143	32	the	the	DT
cord-350019-4nlbu54e	143	33	development	development	NN
cord-350019-4nlbu54e	143	34	of	of	IN
cord-350019-4nlbu54e	143	35	novel	novel	JJ
cord-350019-4nlbu54e	143	36	therapeutic	therapeutic	JJ
cord-350019-4nlbu54e	143	37	targets	target	NNS
cord-350019-4nlbu54e	143	38	for	for	IN
cord-350019-4nlbu54e	143	39	a	a	DT
cord-350019-4nlbu54e	143	40	variety	variety	NN
cord-350019-4nlbu54e	143	41	of	of	IN
cord-350019-4nlbu54e	143	42	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	143	43	diseases	disease	NNS
cord-350019-4nlbu54e	143	44	.	.	.
cord-350019-4nlbu54e	144	1	Additionally	additionally	RB
cord-350019-4nlbu54e	144	2	,	,	,
cord-350019-4nlbu54e	144	3	as	as	IN
cord-350019-4nlbu54e	144	4	previously	previously	RB
cord-350019-4nlbu54e	144	5	mentioned	mention	VBN
cord-350019-4nlbu54e	144	6	,	,	,
cord-350019-4nlbu54e	144	7	XENA	XENA	NNP
cord-350019-4nlbu54e	144	8	or	or	CC
cord-350019-4nlbu54e	144	9	Lnc2Catlas	Lnc2Catlas	NNP
cord-350019-4nlbu54e	144	10	are	be	VBP
cord-350019-4nlbu54e	144	11	databases	database	NNS
cord-350019-4nlbu54e	144	12	that	that	WDT
cord-350019-4nlbu54e	144	13	combine	combine	VBP
cord-350019-4nlbu54e	144	14	RNA	RNA	NNP
cord-350019-4nlbu54e	144	15	sequencing	sequencing	NN
cord-350019-4nlbu54e	144	16	of	of	IN
cord-350019-4nlbu54e	144	17	tissue	tissue	NN
cord-350019-4nlbu54e	144	18	samples	sample	NNS
cord-350019-4nlbu54e	144	19	from	from	IN
cord-350019-4nlbu54e	144	20	healthy	healthy	JJ
cord-350019-4nlbu54e	144	21	and	and	CC
cord-350019-4nlbu54e	144	22	cancer	cancer	NN
cord-350019-4nlbu54e	144	23	patients	patient	NNS
cord-350019-4nlbu54e	144	24	,	,	,
cord-350019-4nlbu54e	144	25	these	these	DT
cord-350019-4nlbu54e	144	26	tools	tool	NNS
cord-350019-4nlbu54e	144	27	can	can	MD
cord-350019-4nlbu54e	144	28	also	also	RB
cord-350019-4nlbu54e	144	29	be	be	VB
cord-350019-4nlbu54e	144	30	adapted	adapt	VBN
cord-350019-4nlbu54e	144	31	to	to	TO
cord-350019-4nlbu54e	144	32	assess	assess	VB
cord-350019-4nlbu54e	144	33	age	age	NN
cord-350019-4nlbu54e	144	34	,	,	,
cord-350019-4nlbu54e	144	35	gender	gender	NN
cord-350019-4nlbu54e	144	36	,	,	,
cord-350019-4nlbu54e	144	37	tissue	tissue	NN
cord-350019-4nlbu54e	144	38	or	or	CC
cord-350019-4nlbu54e	144	39	even	even	RB
cord-350019-4nlbu54e	144	40	disease	disease	NNP
cord-350019-4nlbu54e	144	41	association	association	NNP
cord-350019-4nlbu54e	144	42	of	of	IN
cord-350019-4nlbu54e	144	43	splice	splice	NN
cord-350019-4nlbu54e	144	44	variants	variant	NNS
cord-350019-4nlbu54e	144	45	[	[	-LRB-
cord-350019-4nlbu54e	144	46	98	98	CD
cord-350019-4nlbu54e	144	47	,	,	,
cord-350019-4nlbu54e	144	48	110	110	CD
cord-350019-4nlbu54e	144	49	]	]	-RRB-
cord-350019-4nlbu54e	144	50	.	.	.
cord-350019-4nlbu54e	145	1	These	these	DT
cord-350019-4nlbu54e	145	2	disease	disease	NN
cord-350019-4nlbu54e	145	3	-	-	HYPH
cord-350019-4nlbu54e	145	4	associated	associate	VBN
cord-350019-4nlbu54e	145	5	SNPs	snp	NNS
cord-350019-4nlbu54e	145	6	or	or	CC
cord-350019-4nlbu54e	145	7	splice	splice	NN
cord-350019-4nlbu54e	145	8	variants	variant	NNS
cord-350019-4nlbu54e	145	9	will	will	MD
cord-350019-4nlbu54e	145	10	help	help	VB
cord-350019-4nlbu54e	145	11	guide	guide	VB
cord-350019-4nlbu54e	145	12	further	further	JJ
cord-350019-4nlbu54e	145	13	studies	study	NNS
cord-350019-4nlbu54e	145	14	to	to	TO
cord-350019-4nlbu54e	145	15	determine	determine	VB
cord-350019-4nlbu54e	145	16	therapeutic	therapeutic	JJ
cord-350019-4nlbu54e	145	17	or	or	CC
cord-350019-4nlbu54e	145	18	biomarker	biomarker	NN
cord-350019-4nlbu54e	145	19	potential	potential	NN
cord-350019-4nlbu54e	145	20	.	.	.
cord-350019-4nlbu54e	146	1	In	in	IN
cord-350019-4nlbu54e	146	2	summary	summary	NN
cord-350019-4nlbu54e	146	3	,	,	,
cord-350019-4nlbu54e	146	4	assessing	assess	VBG
cord-350019-4nlbu54e	146	5	disease	disease	NNP
cord-350019-4nlbu54e	146	6	association	association	NNP
cord-350019-4nlbu54e	146	7	by	by	IN
cord-350019-4nlbu54e	146	8	a	a	DT
cord-350019-4nlbu54e	146	9	variety	variety	NN
cord-350019-4nlbu54e	146	10	of	of	IN
cord-350019-4nlbu54e	146	11	databases	database	NNS
cord-350019-4nlbu54e	146	12	can	can	MD
cord-350019-4nlbu54e	146	13	provide	provide	VB
cord-350019-4nlbu54e	146	14	insight	insight	NN
cord-350019-4nlbu54e	146	15	into	into	IN
cord-350019-4nlbu54e	146	16	the	the	DT
cord-350019-4nlbu54e	146	17	function	function	NN
cord-350019-4nlbu54e	146	18	of	of	IN
cord-350019-4nlbu54e	146	19	a	a	DT
cord-350019-4nlbu54e	146	20	lncRNA	lncrna	NN
cord-350019-4nlbu54e	146	21	[	[	-LRB-
cord-350019-4nlbu54e	146	22	112	112	CD
cord-350019-4nlbu54e	146	23	]	]	-RRB-
cord-350019-4nlbu54e	146	24	.	.	.
cord-350019-4nlbu54e	147	1	Unlike	unlike	IN
cord-350019-4nlbu54e	147	2	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	147	3	,	,	,
cord-350019-4nlbu54e	147	4	coding	code	VBG
cord-350019-4nlbu54e	147	5	genes	gene	NNS
cord-350019-4nlbu54e	147	6	are	be	VBP
cord-350019-4nlbu54e	147	7	highly	highly	RB
cord-350019-4nlbu54e	147	8	conserved	conserve	VBN
cord-350019-4nlbu54e	147	9	across	across	IN
cord-350019-4nlbu54e	147	10	distal	distal	JJ
cord-350019-4nlbu54e	147	11	and	and	CC
cord-350019-4nlbu54e	147	12	related	related	JJ
cord-350019-4nlbu54e	147	13	species	specie	NNS
cord-350019-4nlbu54e	147	14	.	.	.
cord-350019-4nlbu54e	148	1	The	the	DT
cord-350019-4nlbu54e	148	2	requirement	requirement	NN
cord-350019-4nlbu54e	148	3	of	of	IN
cord-350019-4nlbu54e	148	4	coding	code	VBG
cord-350019-4nlbu54e	148	5	genes	gene	NNS
cord-350019-4nlbu54e	148	6	to	to	TO
cord-350019-4nlbu54e	148	7	encode	encode	VB
cord-350019-4nlbu54e	148	8	functional	functional	JJ
cord-350019-4nlbu54e	148	9	peptides	peptide	NNS
cord-350019-4nlbu54e	148	10	likely	likely	RB
cord-350019-4nlbu54e	148	11	constrains	constrain	VBZ
cord-350019-4nlbu54e	148	12	the	the	DT
cord-350019-4nlbu54e	148	13	variation	variation	NN
cord-350019-4nlbu54e	148	14	within	within	IN
cord-350019-4nlbu54e	148	15	the	the	DT
cord-350019-4nlbu54e	148	16	open	open	JJ
cord-350019-4nlbu54e	148	17	reading	reading	NN
cord-350019-4nlbu54e	148	18	frame	frame	NN
cord-350019-4nlbu54e	148	19	(	(	-LRB-
cord-350019-4nlbu54e	148	20	ORF	ORF	NNP
cord-350019-4nlbu54e	148	21	)	)	-RRB-
cord-350019-4nlbu54e	148	22	sequence	sequence	NN
cord-350019-4nlbu54e	148	23	[	[	-LRB-
cord-350019-4nlbu54e	148	24	113	113	CD
cord-350019-4nlbu54e	148	25	]	]	-RRB-
cord-350019-4nlbu54e	148	26	.	.	.
cord-350019-4nlbu54e	149	1	LncRNAs	LncRNAs	NNP
cord-350019-4nlbu54e	149	2	by	by	IN
cord-350019-4nlbu54e	149	3	definition	definition	NN
cord-350019-4nlbu54e	149	4	are	be	VBP
cord-350019-4nlbu54e	149	5	not	not	RB
cord-350019-4nlbu54e	149	6	translated	translate	VBN
cord-350019-4nlbu54e	149	7	and	and	CC
cord-350019-4nlbu54e	149	8	often	often	RB
cord-350019-4nlbu54e	149	9	have	have	VBP
cord-350019-4nlbu54e	149	10	poor	poor	JJ
cord-350019-4nlbu54e	149	11	sequence	sequence	NN
cord-350019-4nlbu54e	149	12	conservation	conservation	NN
cord-350019-4nlbu54e	149	13	across	across	IN
cord-350019-4nlbu54e	149	14	related	relate	VBN
cord-350019-4nlbu54e	149	15	species	specie	NNS
cord-350019-4nlbu54e	149	16	.	.	.
cord-350019-4nlbu54e	150	1	Many	many	JJ
cord-350019-4nlbu54e	150	2	lncRNAs	lncrnas	UH
cord-350019-4nlbu54e	150	3	display	display	NN
cord-350019-4nlbu54e	150	4	species	species	NN
cord-350019-4nlbu54e	150	5	-	-	HYPH
cord-350019-4nlbu54e	150	6	specific	specific	JJ
cord-350019-4nlbu54e	150	7	expression	expression	NN
cord-350019-4nlbu54e	150	8	.	.	.
cord-350019-4nlbu54e	151	1	Thus	thus	RB
cord-350019-4nlbu54e	151	2	,	,	,
cord-350019-4nlbu54e	151	3	inferring	infer	VBG
cord-350019-4nlbu54e	151	4	function	function	NN
cord-350019-4nlbu54e	151	5	based	base	VBN
cord-350019-4nlbu54e	151	6	on	on	IN
cord-350019-4nlbu54e	151	7	sequence	sequence	NN
cord-350019-4nlbu54e	151	8	similarity	similarity	NN
cord-350019-4nlbu54e	151	9	is	be	VBZ
cord-350019-4nlbu54e	151	10	a	a	DT
cord-350019-4nlbu54e	151	11	challenge	challenge	NN
cord-350019-4nlbu54e	151	12	(	(	-LRB-
cord-350019-4nlbu54e	151	13	reviewed	review	VBN
cord-350019-4nlbu54e	151	14	in	in	IN
cord-350019-4nlbu54e	151	15	[	[	-LRB-
cord-350019-4nlbu54e	151	16	114	114	CD
cord-350019-4nlbu54e	151	17	]	]	-RRB-
cord-350019-4nlbu54e	151	18	)	)	-RRB-
cord-350019-4nlbu54e	151	19	.	.	.
cord-350019-4nlbu54e	152	1	A	a	DT
cord-350019-4nlbu54e	152	2	more	more	RBR
cord-350019-4nlbu54e	152	3	useful	useful	JJ
cord-350019-4nlbu54e	152	4	conservation	conservation	NN
cord-350019-4nlbu54e	152	5	metric	metric	NN
cord-350019-4nlbu54e	152	6	is	be	VBZ
cord-350019-4nlbu54e	152	7	to	to	TO
cord-350019-4nlbu54e	152	8	assess	assess	VB
cord-350019-4nlbu54e	152	9	whether	whether	IN
cord-350019-4nlbu54e	152	10	the	the	DT
cord-350019-4nlbu54e	152	11	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	152	12	have	have	VBP
cord-350019-4nlbu54e	152	13	conservation	conservation	NN
cord-350019-4nlbu54e	152	14	of	of	IN
cord-350019-4nlbu54e	152	15	synteny	synteny	NNP
cord-350019-4nlbu54e	152	16	(	(	-LRB-
cord-350019-4nlbu54e	152	17	location	location	NN
cord-350019-4nlbu54e	152	18	relative	relative	JJ
cord-350019-4nlbu54e	152	19	to	to	IN
cord-350019-4nlbu54e	152	20	flanking	flanking	JJ
cord-350019-4nlbu54e	152	21	coding	coding	NN
cord-350019-4nlbu54e	152	22	genes	gene	NNS
cord-350019-4nlbu54e	152	23	)	)	-RRB-
cord-350019-4nlbu54e	152	24	,	,	,
cord-350019-4nlbu54e	152	25	along	along	IN
cord-350019-4nlbu54e	152	26	with	with	IN
cord-350019-4nlbu54e	152	27	expression	expression	NN
cord-350019-4nlbu54e	152	28	conservation	conservation	NN
cord-350019-4nlbu54e	152	29	[	[	-LRB-
cord-350019-4nlbu54e	152	30	115	115	CD
cord-350019-4nlbu54e	152	31	]	]	-RRB-
cord-350019-4nlbu54e	152	32	.	.	.
cord-350019-4nlbu54e	153	1	The	the	DT
cord-350019-4nlbu54e	153	2	databases	database	NNS
cord-350019-4nlbu54e	153	3	LNCipedia	LNCipedia	NNP
cord-350019-4nlbu54e	153	4	and	and	CC
cord-350019-4nlbu54e	153	5	NONCODE	NONCODE	NNP
cord-350019-4nlbu54e	153	6	have	have	VBP
cord-350019-4nlbu54e	153	7	user	user	NN
cord-350019-4nlbu54e	153	8	-	-	HYPH
cord-350019-4nlbu54e	153	9	friendly	friendly	JJ
cord-350019-4nlbu54e	153	10	interfaces	interface	NNS
cord-350019-4nlbu54e	153	11	,	,	,
cord-350019-4nlbu54e	153	12	allowing	allow	VBG
cord-350019-4nlbu54e	153	13	assessment	assessment	NN
cord-350019-4nlbu54e	153	14	of	of	IN
cord-350019-4nlbu54e	153	15	both	both	DT
cord-350019-4nlbu54e	153	16	conservation	conservation	NN
cord-350019-4nlbu54e	153	17	of	of	IN
cord-350019-4nlbu54e	153	18	synteny	synteny	NN
cord-350019-4nlbu54e	153	19	and	and	CC
cord-350019-4nlbu54e	153	20	sequence	sequence	NN
cord-350019-4nlbu54e	153	21	for	for	IN
cord-350019-4nlbu54e	153	22	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	153	23	.	.	.
cord-350019-4nlbu54e	154	1	Additionally	additionally	RB
cord-350019-4nlbu54e	154	2	,	,	,
cord-350019-4nlbu54e	154	3	expression	expression	NN
cord-350019-4nlbu54e	154	4	conservation	conservation	NN
cord-350019-4nlbu54e	154	5	can	can	MD
cord-350019-4nlbu54e	154	6	be	be	VB
cord-350019-4nlbu54e	154	7	useful	useful	JJ
cord-350019-4nlbu54e	154	8	to	to	TO
cord-350019-4nlbu54e	154	9	assess	assess	VB
cord-350019-4nlbu54e	154	10	whether	whether	IN
cord-350019-4nlbu54e	154	11	the	the	DT
cord-350019-4nlbu54e	154	12	specific	specific	JJ
cord-350019-4nlbu54e	154	13	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	154	14	has	have	VBZ
cord-350019-4nlbu54e	154	15	the	the	DT
cord-350019-4nlbu54e	154	16	same	same	JJ
cord-350019-4nlbu54e	154	17	biological	biological	JJ
cord-350019-4nlbu54e	154	18	role	role	NN
cord-350019-4nlbu54e	154	19	in	in	IN
cord-350019-4nlbu54e	154	20	similar	similar	JJ
cord-350019-4nlbu54e	154	21	and	and	CC
cord-350019-4nlbu54e	154	22	divergent	divergent	JJ
cord-350019-4nlbu54e	154	23	species	specie	NNS
cord-350019-4nlbu54e	154	24	[	[	-LRB-
cord-350019-4nlbu54e	154	25	116	116	CD
cord-350019-4nlbu54e	154	26	]	]	-RRB-
cord-350019-4nlbu54e	154	27	.	.	.
cord-350019-4nlbu54e	155	1	Conservation	conservation	NN
cord-350019-4nlbu54e	155	2	of	of	IN
cord-350019-4nlbu54e	155	3	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	155	4	expression	expression	NN
cord-350019-4nlbu54e	155	5	can	can	MD
cord-350019-4nlbu54e	155	6	also	also	RB
cord-350019-4nlbu54e	155	7	be	be	VB
cord-350019-4nlbu54e	155	8	indicative	indicative	JJ
cord-350019-4nlbu54e	155	9	of	of	IN
cord-350019-4nlbu54e	155	10	conservation	conservation	NN
cord-350019-4nlbu54e	155	11	of	of	IN
cord-350019-4nlbu54e	155	12	regulatory	regulatory	JJ
cord-350019-4nlbu54e	155	13	regions	region	NNS
cord-350019-4nlbu54e	155	14	,	,	,
cord-350019-4nlbu54e	155	15	such	such	JJ
cord-350019-4nlbu54e	155	16	as	as	IN
cord-350019-4nlbu54e	155	17	transcription	transcription	NN
cord-350019-4nlbu54e	155	18	factor	factor	NN
cord-350019-4nlbu54e	155	19	binding	bind	VBG
cord-350019-4nlbu54e	155	20	sites	site	NNS
cord-350019-4nlbu54e	155	21	within	within	IN
cord-350019-4nlbu54e	155	22	promoters	promoter	NNS
cord-350019-4nlbu54e	155	23	[	[	-LRB-
cord-350019-4nlbu54e	155	24	117	117	CD
cord-350019-4nlbu54e	155	25	]	]	-RRB-
cord-350019-4nlbu54e	155	26	.	.	.
cord-350019-4nlbu54e	156	1	However	however	RB
cord-350019-4nlbu54e	156	2	,	,	,
cord-350019-4nlbu54e	156	3	conservation	conservation	NN
cord-350019-4nlbu54e	156	4	of	of	IN
cord-350019-4nlbu54e	156	5	expression	expression	NN
cord-350019-4nlbu54e	156	6	does	do	VBZ
cord-350019-4nlbu54e	156	7	not	not	RB
cord-350019-4nlbu54e	156	8	necessarily	necessarily	RB
cord-350019-4nlbu54e	156	9	mean	mean	VB
cord-350019-4nlbu54e	156	10	the	the	DT
cord-350019-4nlbu54e	156	11	RNA	RNA	NNP
cord-350019-4nlbu54e	156	12	product	product	NN
cord-350019-4nlbu54e	156	13	is	be	VBZ
cord-350019-4nlbu54e	156	14	important	important	JJ
cord-350019-4nlbu54e	156	15	for	for	IN
cord-350019-4nlbu54e	156	16	lncRNA	lncrna	NN
cord-350019-4nlbu54e	156	17	function	function	NN
cord-350019-4nlbu54e	156	18	.	.	.
cord-350019-4nlbu54e	157	1	Enhancer	Enhancer	NNP
cord-350019-4nlbu54e	157	2	RNAs	rna	NNS
cord-350019-4nlbu54e	157	3	(	(	-LRB-
cord-350019-4nlbu54e	157	4	eRNAs	ernas	CD
cord-350019-4nlbu54e	157	5	)	)	-RRB-
cord-350019-4nlbu54e	157	6	,	,	,
cord-350019-4nlbu54e	157	7	for	for	IN
cord-350019-4nlbu54e	157	8	example	example	NN
cord-350019-4nlbu54e	157	9	,	,	,
cord-350019-4nlbu54e	157	10	are	be	VBP
cord-350019-4nlbu54e	157	11	thought	think	VBN
cord-350019-4nlbu54e	157	12	to	to	TO
cord-350019-4nlbu54e	157	13	predominantly	predominantly	RB
cord-350019-4nlbu54e	157	14	function	function	VB
cord-350019-4nlbu54e	157	15	by	by	IN
cord-350019-4nlbu54e	157	16	creating	create	VBG
cord-350019-4nlbu54e	157	17	a	a	DT
cord-350019-4nlbu54e	157	18	localized	localized	JJ
cord-350019-4nlbu54e	157	19	,	,	,
cord-350019-4nlbu54e	157	20	active	active	JJ
cord-350019-4nlbu54e	157	21	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	157	22	state	state	NN
cord-350019-4nlbu54e	157	23	,	,	,
cord-350019-4nlbu54e	157	24	which	which	WDT
cord-350019-4nlbu54e	157	25	can	can	MD
cord-350019-4nlbu54e	157	26	activate	activate	VB
cord-350019-4nlbu54e	157	27	neighboring	neighboring	NN
cord-350019-4nlbu54e	157	28	genes	gene	NNS
cord-350019-4nlbu54e	157	29	[	[	-LRB-
cord-350019-4nlbu54e	157	30	118	118	CD
cord-350019-4nlbu54e	157	31	]	]	-RRB-
cord-350019-4nlbu54e	157	32	[	[	-LRB-
cord-350019-4nlbu54e	157	33	119	119	CD
cord-350019-4nlbu54e	157	34	]	]	-RRB-
cord-350019-4nlbu54e	157	35	[	[	-LRB-
cord-350019-4nlbu54e	157	36	120	120	CD
cord-350019-4nlbu54e	157	37	]	]	-RRB-
cord-350019-4nlbu54e	157	38	.	.	.
cord-350019-4nlbu54e	158	1	It	-PRON-	PRP
cord-350019-4nlbu54e	158	2	is	be	VBZ
cord-350019-4nlbu54e	158	3	unclear	unclear	JJ
cord-350019-4nlbu54e	158	4	to	to	TO
cord-350019-4nlbu54e	158	5	what	what	WDT
cord-350019-4nlbu54e	158	6	extent	extent	NN
cord-350019-4nlbu54e	158	7	the	the	DT
cord-350019-4nlbu54e	158	8	specific	specific	JJ
cord-350019-4nlbu54e	158	9	RNA	RNA	NNP
cord-350019-4nlbu54e	158	10	sequence	sequence	NN
cord-350019-4nlbu54e	158	11	of	of	IN
cord-350019-4nlbu54e	158	12	eRNAs	eRNAs	NNPS
cord-350019-4nlbu54e	158	13	is	be	VBZ
cord-350019-4nlbu54e	158	14	important	important	JJ
cord-350019-4nlbu54e	158	15	for	for	IN
cord-350019-4nlbu54e	158	16	their	-PRON-	PRP$
cord-350019-4nlbu54e	158	17	function	function	NN
cord-350019-4nlbu54e	158	18	[	[	-LRB-
cord-350019-4nlbu54e	158	19	118	118	CD
cord-350019-4nlbu54e	158	20	]	]	-RRB-
cord-350019-4nlbu54e	158	21	.	.	.
cord-350019-4nlbu54e	159	1	Nevertheless	nevertheless	RB
cord-350019-4nlbu54e	159	2	,	,	,
cord-350019-4nlbu54e	159	3	a	a	DT
cord-350019-4nlbu54e	159	4	couple	couple	NN
cord-350019-4nlbu54e	159	5	of	of	IN
cord-350019-4nlbu54e	159	6	studies	study	NNS
cord-350019-4nlbu54e	159	7	have	have	VBP
cord-350019-4nlbu54e	159	8	provided	provide	VBN
cord-350019-4nlbu54e	159	9	examples	example	NNS
cord-350019-4nlbu54e	159	10	of	of	IN
cord-350019-4nlbu54e	159	11	eRNAs	eRNAs	NNPS
cord-350019-4nlbu54e	159	12	for	for	IN
cord-350019-4nlbu54e	159	13	which	which	WDT
cord-350019-4nlbu54e	159	14	the	the	DT
cord-350019-4nlbu54e	159	15	transcript	transcript	NN
cord-350019-4nlbu54e	159	16	sequence	sequence	NN
cord-350019-4nlbu54e	159	17	was	be	VBD
cord-350019-4nlbu54e	159	18	necessary	necessary	JJ
cord-350019-4nlbu54e	159	19	for	for	IN
cord-350019-4nlbu54e	159	20	their	-PRON-	PRP$
cord-350019-4nlbu54e	159	21	function	function	NN
cord-350019-4nlbu54e	159	22	[	[	-LRB-
cord-350019-4nlbu54e	159	23	121	121	CD
cord-350019-4nlbu54e	159	24	,	,	,
cord-350019-4nlbu54e	159	25	122	122	CD
cord-350019-4nlbu54e	159	26	]	]	-RRB-
cord-350019-4nlbu54e	159	27	.	.	.
cord-350019-4nlbu54e	160	1	To	to	TO
cord-350019-4nlbu54e	160	2	further	further	RB
cord-350019-4nlbu54e	160	3	investigate	investigate	VB
cord-350019-4nlbu54e	160	4	conservation	conservation	NN
cord-350019-4nlbu54e	160	5	of	of	IN
cord-350019-4nlbu54e	160	6	a	a	DT
cord-350019-4nlbu54e	160	7	candidate	candidate	NN
cord-350019-4nlbu54e	160	8	,	,	,
cord-350019-4nlbu54e	160	9	BLAST	blast	NN
cord-350019-4nlbu54e	160	10	(	(	-LRB-
cord-350019-4nlbu54e	160	11	basic	basic	JJ
cord-350019-4nlbu54e	160	12	local	local	JJ
cord-350019-4nlbu54e	160	13	alignment	alignment	NN
cord-350019-4nlbu54e	160	14	search	search	NN
cord-350019-4nlbu54e	160	15	tool	tool	NN
cord-350019-4nlbu54e	160	16	)	)	-RRB-
cord-350019-4nlbu54e	160	17	on	on	IN
cord-350019-4nlbu54e	160	18	NCBI	NCBI	NNP
cord-350019-4nlbu54e	160	19	(	(	-LRB-
cord-350019-4nlbu54e	160	20	national	national	NNP
cord-350019-4nlbu54e	160	21	center	center	NNP
cord-350019-4nlbu54e	160	22	for	for	IN
cord-350019-4nlbu54e	160	23	biotechnology	biotechnology	NN
cord-350019-4nlbu54e	160	24	information	information	NN
cord-350019-4nlbu54e	160	25	)	)	-RRB-
cord-350019-4nlbu54e	160	26	can	can	MD
cord-350019-4nlbu54e	160	27	be	be	VB
cord-350019-4nlbu54e	160	28	utilized	utilize	VBN
cord-350019-4nlbu54e	160	29	to	to	TO
cord-350019-4nlbu54e	160	30	explore	explore	VB
cord-350019-4nlbu54e	160	31	conservation	conservation	NN
cord-350019-4nlbu54e	160	32	across	across	IN
cord-350019-4nlbu54e	160	33	species	specie	NNS
cord-350019-4nlbu54e	160	34	[	[	-LRB-
cord-350019-4nlbu54e	160	35	123	123	CD
cord-350019-4nlbu54e	160	36	]	]	-RRB-
cord-350019-4nlbu54e	160	37	or	or	CC
cord-350019-4nlbu54e	160	38	lncRNAdb	lncRNAdb	NNS
cord-350019-4nlbu54e	160	39	v2.0	v2.0	JJ
cord-350019-4nlbu54e	160	40	[	[	-LRB-
cord-350019-4nlbu54e	160	41	124	124	CD
cord-350019-4nlbu54e	160	42	]	]	-RRB-
cord-350019-4nlbu54e	160	43	,	,	,
cord-350019-4nlbu54e	160	44	by	by	IN
cord-350019-4nlbu54e	160	45	inputting	inputte	VBG
cord-350019-4nlbu54e	160	46	the	the	DT
cord-350019-4nlbu54e	160	47	entire	entire	JJ
cord-350019-4nlbu54e	160	48	sequence	sequence	NN
cord-350019-4nlbu54e	160	49	of	of	IN
cord-350019-4nlbu54e	160	50	a	a	DT
cord-350019-4nlbu54e	160	51	lncRNA	lncrna	NN
cord-350019-4nlbu54e	160	52	of	of	IN
cord-350019-4nlbu54e	160	53	interest	interest	NN
cord-350019-4nlbu54e	160	54	.	.	.
cord-350019-4nlbu54e	161	1	If	if	IN
cord-350019-4nlbu54e	161	2	a	a	DT
cord-350019-4nlbu54e	161	3	lncRNA	lncrna	NN
cord-350019-4nlbu54e	161	4	has	have	VBZ
cord-350019-4nlbu54e	161	5	a	a	DT
cord-350019-4nlbu54e	161	6	known	know	VBN
cord-350019-4nlbu54e	161	7	structure	structure	NN
cord-350019-4nlbu54e	161	8	,	,	,
cord-350019-4nlbu54e	161	9	inputting	inputte	VBG
cord-350019-4nlbu54e	161	10	the	the	DT
cord-350019-4nlbu54e	161	11	shorter	short	JJR
cord-350019-4nlbu54e	161	12	structured	structure	VBN
cord-350019-4nlbu54e	161	13	RNA	RNA	NNP
cord-350019-4nlbu54e	161	14	sequence	sequence	NN
cord-350019-4nlbu54e	161	15	can	can	MD
cord-350019-4nlbu54e	161	16	enhance	enhance	VB
cord-350019-4nlbu54e	161	17	conservation	conservation	NN
cord-350019-4nlbu54e	161	18	results	result	NNS
cord-350019-4nlbu54e	161	19	.	.	.
cord-350019-4nlbu54e	162	1	One	one	PRP
cord-350019-4nlbu54e	162	2	can	can	MD
cord-350019-4nlbu54e	162	3	also	also	RB
cord-350019-4nlbu54e	162	4	,	,	,
cord-350019-4nlbu54e	162	5	view	view	VB
cord-350019-4nlbu54e	162	6	the	the	DT
cord-350019-4nlbu54e	162	7	conservation	conservation	NN
cord-350019-4nlbu54e	162	8	track	track	NN
cord-350019-4nlbu54e	162	9	of	of	IN
cord-350019-4nlbu54e	162	10	the	the	DT
cord-350019-4nlbu54e	162	11	UCSC	UCSC	NNP
cord-350019-4nlbu54e	162	12	genome	genome	NN
cord-350019-4nlbu54e	162	13	browser	browser	NN
cord-350019-4nlbu54e	162	14	[	[	-LRB-
cord-350019-4nlbu54e	162	15	125	125	CD
cord-350019-4nlbu54e	162	16	]	]	-RRB-
cord-350019-4nlbu54e	162	17	to	to	TO
cord-350019-4nlbu54e	162	18	assess	assess	VB
cord-350019-4nlbu54e	162	19	if	if	IN
cord-350019-4nlbu54e	162	20	this	this	DT
cord-350019-4nlbu54e	162	21	specific	specific	JJ
cord-350019-4nlbu54e	162	22	sequence	sequence	NN
cord-350019-4nlbu54e	162	23	within	within	IN
cord-350019-4nlbu54e	162	24	the	the	DT
cord-350019-4nlbu54e	162	25	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	162	26	transcript	transcript	NN
cord-350019-4nlbu54e	162	27	is	be	VBZ
cord-350019-4nlbu54e	162	28	conserved	conserve	VBN
cord-350019-4nlbu54e	162	29	across	across	IN
cord-350019-4nlbu54e	162	30	species	specie	NNS
cord-350019-4nlbu54e	162	31	.	.	.
cord-350019-4nlbu54e	163	1	In	in	IN
cord-350019-4nlbu54e	163	2	summary	summary	NN
cord-350019-4nlbu54e	163	3	,	,	,
cord-350019-4nlbu54e	163	4	conservation	conservation	NN
cord-350019-4nlbu54e	163	5	of	of	IN
cord-350019-4nlbu54e	163	6	a	a	DT
cord-350019-4nlbu54e	163	7	lncRNA	lncrna	NN
cord-350019-4nlbu54e	163	8	is	be	VBZ
cord-350019-4nlbu54e	163	9	complicated	complicated	JJ
cord-350019-4nlbu54e	163	10	to	to	TO
cord-350019-4nlbu54e	163	11	assess	assess	VB
cord-350019-4nlbu54e	163	12	using	use	VBG
cord-350019-4nlbu54e	163	13	current	current	JJ
cord-350019-4nlbu54e	163	14	bioinformatic	bioinformatic	JJ
cord-350019-4nlbu54e	163	15	methods	method	NNS
cord-350019-4nlbu54e	163	16	.	.	.
cord-350019-4nlbu54e	164	1	However	however	RB
cord-350019-4nlbu54e	164	2	,	,	,
cord-350019-4nlbu54e	164	3	understanding	understand	VBG
cord-350019-4nlbu54e	164	4	if	if	IN
cord-350019-4nlbu54e	164	5	there	there	EX
cord-350019-4nlbu54e	164	6	is	be	VBZ
cord-350019-4nlbu54e	164	7	a	a	DT
cord-350019-4nlbu54e	164	8	functional	functional	JJ
cord-350019-4nlbu54e	164	9	motif	motif	NN
cord-350019-4nlbu54e	164	10	(	(	-LRB-
cord-350019-4nlbu54e	164	11	therefore	therefore	RB
cord-350019-4nlbu54e	164	12	a	a	DT
cord-350019-4nlbu54e	164	13	shorter	short	JJR
cord-350019-4nlbu54e	164	14	starting	start	VBG
cord-350019-4nlbu54e	164	15	input	input	NN
cord-350019-4nlbu54e	164	16	sequence	sequence	NN
cord-350019-4nlbu54e	164	17	)	)	-RRB-
cord-350019-4nlbu54e	164	18	within	within	IN
cord-350019-4nlbu54e	164	19	a	a	DT
cord-350019-4nlbu54e	164	20	lncRNA	lncrna	NN
cord-350019-4nlbu54e	164	21	can	can	MD
cord-350019-4nlbu54e	164	22	allow	allow	VB
cord-350019-4nlbu54e	164	23	for	for	IN
cord-350019-4nlbu54e	164	24	an	an	DT
cord-350019-4nlbu54e	164	25	increased	increase	VBN
cord-350019-4nlbu54e	164	26	assessment	assessment	NN
cord-350019-4nlbu54e	164	27	of	of	IN
cord-350019-4nlbu54e	164	28	functional	functional	JJ
cord-350019-4nlbu54e	164	29	conservation	conservation	NN
cord-350019-4nlbu54e	164	30	across	across	IN
cord-350019-4nlbu54e	164	31	species	specie	NNS
cord-350019-4nlbu54e	164	32	.	.	.
cord-350019-4nlbu54e	165	1	Activation	activation	NN
cord-350019-4nlbu54e	165	2	of	of	IN
cord-350019-4nlbu54e	165	3	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	165	4	pathways	pathway	NNS
cord-350019-4nlbu54e	165	5	result	result	VBP
cord-350019-4nlbu54e	165	6	in	in	IN
cord-350019-4nlbu54e	165	7	both	both	CC
cord-350019-4nlbu54e	165	8	up	up	IN
cord-350019-4nlbu54e	165	9	and	and	CC
cord-350019-4nlbu54e	165	10	down	down	IN
cord-350019-4nlbu54e	165	11	regulation	regulation	NN
cord-350019-4nlbu54e	165	12	of	of	IN
cord-350019-4nlbu54e	165	13	specific	specific	JJ
cord-350019-4nlbu54e	165	14	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	165	15	,	,	,
cord-350019-4nlbu54e	165	16	which	which	WDT
cord-350019-4nlbu54e	165	17	in	in	IN
cord-350019-4nlbu54e	165	18	turn	turn	NN
cord-350019-4nlbu54e	165	19	can	can	MD
cord-350019-4nlbu54e	165	20	have	have	VB
cord-350019-4nlbu54e	165	21	either	either	CC
cord-350019-4nlbu54e	165	22	positive	positive	JJ
cord-350019-4nlbu54e	165	23	or	or	CC
cord-350019-4nlbu54e	165	24	negative	negative	JJ
cord-350019-4nlbu54e	165	25	regulatory	regulatory	JJ
cord-350019-4nlbu54e	165	26	effects	effect	NNS
cord-350019-4nlbu54e	165	27	on	on	IN
cord-350019-4nlbu54e	165	28	the	the	DT
cord-350019-4nlbu54e	165	29	pathway	pathway	NN
cord-350019-4nlbu54e	165	30	,	,	,
cord-350019-4nlbu54e	165	31	such	such	JJ
cord-350019-4nlbu54e	165	32	as	as	IN
cord-350019-4nlbu54e	165	33	activation	activation	NN
cord-350019-4nlbu54e	165	34	of	of	IN
cord-350019-4nlbu54e	165	35	sequestered	sequester	VBN
cord-350019-4nlbu54e	165	36	transcription	transcription	NN
cord-350019-4nlbu54e	165	37	factors	factor	NNS
cord-350019-4nlbu54e	165	38	[	[	-LRB-
cord-350019-4nlbu54e	165	39	45	45	CD
cord-350019-4nlbu54e	165	40	,	,	,
cord-350019-4nlbu54e	165	41	126	126	CD
cord-350019-4nlbu54e	165	42	]	]	-RRB-
cord-350019-4nlbu54e	165	43	or	or	CC
cord-350019-4nlbu54e	165	44	enhanced	enhance	VBN
cord-350019-4nlbu54e	165	45	or	or	CC
cord-350019-4nlbu54e	165	46	repressed	repressed	JJ
cord-350019-4nlbu54e	165	47	expression	expression	NN
cord-350019-4nlbu54e	165	48	of	of	IN
cord-350019-4nlbu54e	165	49	specific	specific	JJ
cord-350019-4nlbu54e	165	50	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	165	51	cytokines	cytokine	NNS
cord-350019-4nlbu54e	165	52	[	[	-LRB-
cord-350019-4nlbu54e	165	53	61	61	CD
cord-350019-4nlbu54e	165	54	,	,	,
cord-350019-4nlbu54e	165	55	84	84	CD
cord-350019-4nlbu54e	165	56	,	,	,
cord-350019-4nlbu54e	165	57	127	127	CD
cord-350019-4nlbu54e	165	58	]	]	-RRB-
cord-350019-4nlbu54e	165	59	.	.	.
cord-350019-4nlbu54e	166	1	Genes	gene	NNS
cord-350019-4nlbu54e	166	2	that	that	WDT
cord-350019-4nlbu54e	166	3	are	be	VBP
cord-350019-4nlbu54e	166	4	immediate	immediate	JJ
cord-350019-4nlbu54e	166	5	regulators	regulator	NNS
cord-350019-4nlbu54e	166	6	of	of	IN
cord-350019-4nlbu54e	166	7	immunity	immunity	NN
cord-350019-4nlbu54e	166	8	are	be	VBP
cord-350019-4nlbu54e	166	9	poised	poise	VBN
cord-350019-4nlbu54e	166	10	for	for	IN
cord-350019-4nlbu54e	166	11	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	166	12	activation	activation	NN
cord-350019-4nlbu54e	166	13	,	,	,
cord-350019-4nlbu54e	166	14	which	which	WDT
cord-350019-4nlbu54e	166	15	can	can	MD
cord-350019-4nlbu54e	166	16	be	be	VB
cord-350019-4nlbu54e	166	17	assessed	assess	VBN
cord-350019-4nlbu54e	166	18	by	by	IN
cord-350019-4nlbu54e	166	19	defining	define	VBG
cord-350019-4nlbu54e	166	20	the	the	DT
cord-350019-4nlbu54e	166	21	openness	openness	NN
cord-350019-4nlbu54e	166	22	of	of	IN
cord-350019-4nlbu54e	166	23	promoter	promoter	NN
cord-350019-4nlbu54e	166	24	regions	region	NNS
cord-350019-4nlbu54e	166	25	of	of	IN
cord-350019-4nlbu54e	166	26	a	a	DT
cord-350019-4nlbu54e	166	27	lncRNA	lncrna	FW
cord-350019-4nlbu54e	166	28	pre	pre	JJ
cord-350019-4nlbu54e	166	29	-	-	JJ
cord-350019-4nlbu54e	166	30	and	and	CC
cord-350019-4nlbu54e	166	31	post	post	JJ
cord-350019-4nlbu54e	166	32	-	-	JJ
cord-350019-4nlbu54e	166	33	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	166	34	stimulation	stimulation	NN
cord-350019-4nlbu54e	166	35	.	.	.
cord-350019-4nlbu54e	167	1	Common	common	JJ
cord-350019-4nlbu54e	167	2	methods	method	NNS
cord-350019-4nlbu54e	167	3	for	for	IN
cord-350019-4nlbu54e	167	4	assessing	assess	VBG
cord-350019-4nlbu54e	167	5	chromatin	chromatin	NN
cord-350019-4nlbu54e	167	6	accessibility	accessibility	NN
cord-350019-4nlbu54e	167	7	of	of	IN
cord-350019-4nlbu54e	167	8	promoters	promoter	NNS
cord-350019-4nlbu54e	167	9	include	include	VBP
cord-350019-4nlbu54e	167	10	DNase	DNase	NNP
cord-350019-4nlbu54e	167	11	-	-	HYPH
cord-350019-4nlbu54e	167	12	hyper	hyper	NN
cord-350019-4nlbu54e	167	13	-	-	NN
cord-350019-4nlbu54e	167	14	sensitivity	sensitivity	NN
cord-350019-4nlbu54e	167	15	(	(	-LRB-
cord-350019-4nlbu54e	167	16	DNAseHS	DNAseHS	NNP
cord-350019-4nlbu54e	167	17	)	)	-RRB-
cord-350019-4nlbu54e	167	18	[	[	-LRB-
cord-350019-4nlbu54e	167	19	128	128	CD
cord-350019-4nlbu54e	167	20	]	]	-RRB-
cord-350019-4nlbu54e	167	21	and	and	CC
cord-350019-4nlbu54e	167	22	the	the	DT
cord-350019-4nlbu54e	167	23	Assay	Assay	NNP
cord-350019-4nlbu54e	167	24	for	for	IN
cord-350019-4nlbu54e	167	25	Transposase	Transposase	NNP
cord-350019-4nlbu54e	167	26	-	-	HYPH
cord-350019-4nlbu54e	167	27	Accessible	Accessible	NNP
cord-350019-4nlbu54e	167	28	Chromatin	Chromatin	NNP
cord-350019-4nlbu54e	167	29	(	(	-LRB-
cord-350019-4nlbu54e	167	30	ATAC	ATAC	NNP
cord-350019-4nlbu54e	167	31	)	)	-RRB-
cord-350019-4nlbu54e	167	32	[	[	-LRB-
cord-350019-4nlbu54e	167	33	129	129	CD
cord-350019-4nlbu54e	167	34	]	]	-RRB-
cord-350019-4nlbu54e	167	35	.	.	.
cord-350019-4nlbu54e	168	1	DNAse	DNAse	NNP
cord-350019-4nlbu54e	168	2	HS	HS	NNP
cord-350019-4nlbu54e	168	3	-	-	HYPH
cord-350019-4nlbu54e	168	4	seq	seq	NNP
cord-350019-4nlbu54e	168	5	and	and	CC
cord-350019-4nlbu54e	168	6	ATAC	ATAC	NNP
cord-350019-4nlbu54e	168	7	-	-	HYPH
cord-350019-4nlbu54e	168	8	seq	seq	NN
cord-350019-4nlbu54e	168	9	datasets	dataset	NNS
cord-350019-4nlbu54e	168	10	are	be	VBP
cord-350019-4nlbu54e	168	11	available	available	JJ
cord-350019-4nlbu54e	168	12	from	from	IN
cord-350019-4nlbu54e	168	13	a	a	DT
cord-350019-4nlbu54e	168	14	variety	variety	NN
cord-350019-4nlbu54e	168	15	of	of	IN
cord-350019-4nlbu54e	168	16	tissues	tissue	NNS
cord-350019-4nlbu54e	168	17	on	on	IN
cord-350019-4nlbu54e	168	18	ENCODE	encode	NN
cord-350019-4nlbu54e	168	19	for	for	IN
cord-350019-4nlbu54e	168	20	both	both	DT
cord-350019-4nlbu54e	168	21	mouse	mouse	NN
cord-350019-4nlbu54e	168	22	and	and	CC
cord-350019-4nlbu54e	168	23	humans	human	NNS
cord-350019-4nlbu54e	169	1	(	(	-LRB-
cord-350019-4nlbu54e	169	2	Tables	table	NNS
cord-350019-4nlbu54e	169	3	1	1	CD
cord-350019-4nlbu54e	169	4	and	and	CC
cord-350019-4nlbu54e	169	5	2	2	CD
cord-350019-4nlbu54e	169	6	)	)	-RRB-
cord-350019-4nlbu54e	169	7	.	.	.
cord-350019-4nlbu54e	170	1	If	if	IN
cord-350019-4nlbu54e	170	2	the	the	DT
cord-350019-4nlbu54e	170	3	promoter	promoter	NN
cord-350019-4nlbu54e	170	4	is	be	VBZ
cord-350019-4nlbu54e	170	5	open	open	JJ
cord-350019-4nlbu54e	170	6	(	(	-LRB-
cord-350019-4nlbu54e	170	7	accessible	accessible	JJ
cord-350019-4nlbu54e	170	8	)	)	-RRB-
cord-350019-4nlbu54e	170	9	,	,	,
cord-350019-4nlbu54e	170	10	this	this	DT
cord-350019-4nlbu54e	170	11	is	be	VBZ
cord-350019-4nlbu54e	170	12	indicative	indicative	JJ
cord-350019-4nlbu54e	170	13	of	of	IN
cord-350019-4nlbu54e	170	14	either	either	CC
cord-350019-4nlbu54e	170	15	a	a	DT
cord-350019-4nlbu54e	170	16	poised	poised	JJ
cord-350019-4nlbu54e	170	17	or	or	CC
cord-350019-4nlbu54e	170	18	actively	actively	RB
cord-350019-4nlbu54e	170	19	transcribed	transcribe	VBN
cord-350019-4nlbu54e	170	20	gene	gene	NN
cord-350019-4nlbu54e	170	21	.	.	.
cord-350019-4nlbu54e	171	1	Accessibility	accessibility	NN
cord-350019-4nlbu54e	171	2	of	of	IN
cord-350019-4nlbu54e	171	3	promoter	promoter	NN
cord-350019-4nlbu54e	171	4	regions	region	NNS
cord-350019-4nlbu54e	171	5	in	in	IN
cord-350019-4nlbu54e	171	6	the	the	DT
cord-350019-4nlbu54e	171	7	hematopoietic	hematopoietic	JJ
cord-350019-4nlbu54e	171	8	cell	cell	NN
cord-350019-4nlbu54e	171	9	lineage	lineage	NN
cord-350019-4nlbu54e	171	10	was	be	VBD
cord-350019-4nlbu54e	171	11	assessed	assess	VBN
cord-350019-4nlbu54e	171	12	by	by	IN
cord-350019-4nlbu54e	171	13	Lara	Lara	NNP
cord-350019-4nlbu54e	171	14	-	-	HYPH
cord-350019-4nlbu54e	171	15	Astiaso	Astiaso	NNP
cord-350019-4nlbu54e	171	16	et	et	NNP
cord-350019-4nlbu54e	171	17	al	al	NNP
cord-350019-4nlbu54e	171	18	.	.	.
cord-350019-4nlbu54e	172	1	through	through	IN
cord-350019-4nlbu54e	172	2	performing	perform	VBG
cord-350019-4nlbu54e	172	3	ATAC	ATAC	NNP
cord-350019-4nlbu54e	172	4	-	-	HYPH
cord-350019-4nlbu54e	172	5	seq	seq	NNP
cord-350019-4nlbu54e	172	6	for	for	IN
cord-350019-4nlbu54e	172	7	all	all	DT
cord-350019-4nlbu54e	172	8	cells	cell	NNS
cord-350019-4nlbu54e	172	9	in	in	IN
cord-350019-4nlbu54e	172	10	the	the	DT
cord-350019-4nlbu54e	172	11	hematopoietic	hematopoietic	JJ
cord-350019-4nlbu54e	172	12	lineage	lineage	NN
cord-350019-4nlbu54e	172	13	[	[	-LRB-
cord-350019-4nlbu54e	172	14	76	76	CD
cord-350019-4nlbu54e	172	15	]	]	-RRB-
cord-350019-4nlbu54e	172	16	.	.	.
cord-350019-4nlbu54e	173	1	This	this	DT
cord-350019-4nlbu54e	173	2	dataset	dataset	NN
cord-350019-4nlbu54e	173	3	provides	provide	VBZ
cord-350019-4nlbu54e	173	4	insight	insight	NN
cord-350019-4nlbu54e	173	5	into	into	IN
cord-350019-4nlbu54e	173	6	a	a	DT
cord-350019-4nlbu54e	173	7	gene	gene	NN
cord-350019-4nlbu54e	173	8	's	's	POS
cord-350019-4nlbu54e	173	9	promoter	promoter	NN
cord-350019-4nlbu54e	173	10	accessibility	accessibility	NN
cord-350019-4nlbu54e	173	11	,	,	,
cord-350019-4nlbu54e	173	12	as	as	RB
cord-350019-4nlbu54e	173	13	well	well	RB
cord-350019-4nlbu54e	173	14	as	as	IN
cord-350019-4nlbu54e	173	15	cell	cell	NN
cord-350019-4nlbu54e	173	16	type	type	NN
cord-350019-4nlbu54e	173	17	specificity	specificity	NN
cord-350019-4nlbu54e	173	18	.	.	.
cord-350019-4nlbu54e	174	1	For	for	IN
cord-350019-4nlbu54e	174	2	instance	instance	NN
cord-350019-4nlbu54e	174	3	,	,	,
cord-350019-4nlbu54e	174	4	if	if	IN
cord-350019-4nlbu54e	174	5	the	the	DT
cord-350019-4nlbu54e	174	6	promoter	promoter	NN
cord-350019-4nlbu54e	174	7	is	be	VBZ
cord-350019-4nlbu54e	174	8	open	open	JJ
cord-350019-4nlbu54e	174	9	in	in	IN
cord-350019-4nlbu54e	174	10	all	all	DT
cord-350019-4nlbu54e	174	11	cell	cell	NN
cord-350019-4nlbu54e	174	12	types	type	NNS
cord-350019-4nlbu54e	174	13	,	,	,
cord-350019-4nlbu54e	174	14	it	-PRON-	PRP
cord-350019-4nlbu54e	174	15	shows	show	VBZ
cord-350019-4nlbu54e	174	16	that	that	IN
cord-350019-4nlbu54e	174	17	it	-PRON-	PRP
cord-350019-4nlbu54e	174	18	is	be	VBZ
cord-350019-4nlbu54e	174	19	ubiquitously	ubiquitously	RB
cord-350019-4nlbu54e	174	20	accessible	accessible	JJ
cord-350019-4nlbu54e	174	21	and	and	CC
cord-350019-4nlbu54e	174	22	possibly	possibly	RB
cord-350019-4nlbu54e	174	23	expressed	express	VBN
cord-350019-4nlbu54e	174	24	,	,	,
cord-350019-4nlbu54e	174	25	while	while	IN
cord-350019-4nlbu54e	174	26	if	if	IN
cord-350019-4nlbu54e	174	27	a	a	DT
cord-350019-4nlbu54e	174	28	promoter	promoter	NN
cord-350019-4nlbu54e	174	29	is	be	VBZ
cord-350019-4nlbu54e	174	30	only	only	RB
cord-350019-4nlbu54e	174	31	accessible	accessible	JJ
cord-350019-4nlbu54e	174	32	in	in	IN
cord-350019-4nlbu54e	174	33	myeloid	myeloid	JJ
cord-350019-4nlbu54e	174	34	cells	cell	NNS
cord-350019-4nlbu54e	174	35	or	or	CC
cord-350019-4nlbu54e	174	36	terminally	terminally	RB
cord-350019-4nlbu54e	174	37	differentiated	differentiate	VBN
cord-350019-4nlbu54e	174	38	macrophages	macrophage	NNS
cord-350019-4nlbu54e	174	39	this	this	DT
cord-350019-4nlbu54e	174	40	provides	provide	VBZ
cord-350019-4nlbu54e	174	41	insight	insight	NN
cord-350019-4nlbu54e	174	42	into	into	IN
cord-350019-4nlbu54e	174	43	the	the	DT
cord-350019-4nlbu54e	174	44	cell	cell	NN
cord-350019-4nlbu54e	174	45	type	type	NN
cord-350019-4nlbu54e	174	46	that	that	WDT
cord-350019-4nlbu54e	174	47	could	could	MD
cord-350019-4nlbu54e	174	48	be	be	VB
cord-350019-4nlbu54e	174	49	most	most	RBS
cord-350019-4nlbu54e	174	50	biologically	biologically	RB
cord-350019-4nlbu54e	174	51	relevant	relevant	JJ
cord-350019-4nlbu54e	174	52	for	for	IN
cord-350019-4nlbu54e	174	53	a	a	DT
cord-350019-4nlbu54e	174	54	particular	particular	JJ
cord-350019-4nlbu54e	174	55	lncRNA	lncrna	NN
cord-350019-4nlbu54e	174	56	.	.	.
cord-350019-4nlbu54e	175	1	Another	another	DT
cord-350019-4nlbu54e	175	2	interesting	interesting	JJ
cord-350019-4nlbu54e	175	3	data	datum	NNS
cord-350019-4nlbu54e	175	4	set	set	VBN
cord-350019-4nlbu54e	175	5	from	from	IN
cord-350019-4nlbu54e	175	6	Tong	Tong	NNP
cord-350019-4nlbu54e	175	7	et	et	NNP
cord-350019-4nlbu54e	175	8	al	al	NNP
cord-350019-4nlbu54e	175	9	.	.	NNP
cord-350019-4nlbu54e	175	10	have	have	VBP
cord-350019-4nlbu54e	175	11	provided	provide	VBN
cord-350019-4nlbu54e	175	12	ATAC	ATAC	NNP
cord-350019-4nlbu54e	175	13	sequencing	sequence	VBG
cord-350019-4nlbu54e	175	14	from	from	IN
cord-350019-4nlbu54e	175	15	bone	bone	NN
cord-350019-4nlbu54e	175	16	marrow	marrow	NN
cord-350019-4nlbu54e	175	17	derived	derive	VBN
cord-350019-4nlbu54e	175	18	macrophages	macrophage	NNS
cord-350019-4nlbu54e	175	19	(	(	-LRB-
cord-350019-4nlbu54e	175	20	BMDMs	bmdm	NNS
cord-350019-4nlbu54e	175	21	)	)	-RRB-
cord-350019-4nlbu54e	175	22	pre	pre	VB
cord-350019-4nlbu54e	175	23	-	-	JJ
cord-350019-4nlbu54e	175	24	and	and	CC
cord-350019-4nlbu54e	175	25	post	post	JJ
cord-350019-4nlbu54e	175	26	-	-	JJ
cord-350019-4nlbu54e	175	27	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	175	28	time	time	NN
cord-350019-4nlbu54e	175	29	course	course	NN
cord-350019-4nlbu54e	175	30	stimulation	stimulation	NN
cord-350019-4nlbu54e	175	31	[	[	-LRB-
cord-350019-4nlbu54e	175	32	72	72	CD
cord-350019-4nlbu54e	175	33	]	]	-RRB-
cord-350019-4nlbu54e	175	34	.	.	.
cord-350019-4nlbu54e	176	1	This	this	DT
cord-350019-4nlbu54e	176	2	dataset	dataset	NN
cord-350019-4nlbu54e	176	3	assesses	assess	VBZ
cord-350019-4nlbu54e	176	4	both	both	DT
cord-350019-4nlbu54e	176	5	poised	poise	VBN
cord-350019-4nlbu54e	176	6	genes	gene	NNS
cord-350019-4nlbu54e	176	7	and	and	CC
cord-350019-4nlbu54e	176	8	genes	gene	NNS
cord-350019-4nlbu54e	176	9	that	that	WDT
cord-350019-4nlbu54e	176	10	undergo	undergo	VBP
cord-350019-4nlbu54e	176	11	promoter	promoter	NN
cord-350019-4nlbu54e	176	12	remodeling	remodeling	NN
cord-350019-4nlbu54e	176	13	during	during	IN
cord-350019-4nlbu54e	176	14	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	176	15	activation	activation	NN
cord-350019-4nlbu54e	176	16	.	.	.
cord-350019-4nlbu54e	177	1	If	if	IN
cord-350019-4nlbu54e	177	2	a	a	DT
cord-350019-4nlbu54e	177	3	promoter	promoter	NN
cord-350019-4nlbu54e	177	4	of	of	IN
cord-350019-4nlbu54e	177	5	a	a	DT
cord-350019-4nlbu54e	177	6	lncRNA	lncrna	NN
cord-350019-4nlbu54e	177	7	is	be	VBZ
cord-350019-4nlbu54e	177	8	inaccessible	inaccessible	JJ
cord-350019-4nlbu54e	177	9	or	or	CC
cord-350019-4nlbu54e	177	10	accessible	accessible	JJ
cord-350019-4nlbu54e	177	11	during	during	IN
cord-350019-4nlbu54e	177	12	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	177	13	stimulation	stimulation	NN
cord-350019-4nlbu54e	177	14	,	,	,
cord-350019-4nlbu54e	177	15	this	this	DT
cord-350019-4nlbu54e	177	16	could	could	MD
cord-350019-4nlbu54e	177	17	provide	provide	VB
cord-350019-4nlbu54e	177	18	insight	insight	NN
cord-350019-4nlbu54e	177	19	to	to	IN
cord-350019-4nlbu54e	177	20	its	-PRON-	PRP$
cord-350019-4nlbu54e	177	21	regulation	regulation	NN
cord-350019-4nlbu54e	177	22	and	and	CC
cord-350019-4nlbu54e	177	23	biological	biological	JJ
cord-350019-4nlbu54e	177	24	significance	significance	NN
cord-350019-4nlbu54e	177	25	during	during	IN
cord-350019-4nlbu54e	177	26	an	an	DT
cord-350019-4nlbu54e	177	27	immune	immune	JJ
cord-350019-4nlbu54e	177	28	response	response	NN
cord-350019-4nlbu54e	177	29	.	.	.
cord-350019-4nlbu54e	178	1	Once	once	IN
cord-350019-4nlbu54e	178	2	the	the	DT
cord-350019-4nlbu54e	178	3	accessibility	accessibility	NN
cord-350019-4nlbu54e	178	4	of	of	IN
cord-350019-4nlbu54e	178	5	a	a	DT
cord-350019-4nlbu54e	178	6	promoter	promoter	NN
cord-350019-4nlbu54e	178	7	region	region	NN
cord-350019-4nlbu54e	178	8	is	be	VBZ
cord-350019-4nlbu54e	178	9	determined	determine	VBN
cord-350019-4nlbu54e	178	10	,	,	,
cord-350019-4nlbu54e	178	11	defining	define	VBG
cord-350019-4nlbu54e	178	12	post	post	JJ
cord-350019-4nlbu54e	178	13	-	-	JJ
cord-350019-4nlbu54e	178	14	translational	translational	JJ
cord-350019-4nlbu54e	178	15	modifications	modification	NNS
cord-350019-4nlbu54e	178	16	of	of	IN
cord-350019-4nlbu54e	178	17	histones	histone	NNS
cord-350019-4nlbu54e	178	18	on	on	IN
cord-350019-4nlbu54e	178	19	promoter	promoter	NN
cord-350019-4nlbu54e	178	20	regions	region	NNS
cord-350019-4nlbu54e	178	21	will	will	MD
cord-350019-4nlbu54e	178	22	assess	assess	VB
cord-350019-4nlbu54e	178	23	promoter	promoter	NN
cord-350019-4nlbu54e	178	24	activity	activity	NN
cord-350019-4nlbu54e	178	25	in	in	IN
cord-350019-4nlbu54e	178	26	specific	specific	JJ
cord-350019-4nlbu54e	178	27	cell	cell	NN
cord-350019-4nlbu54e	178	28	types	type	NNS
cord-350019-4nlbu54e	178	29	or	or	CC
cord-350019-4nlbu54e	178	30	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	178	31	states	state	NNS
cord-350019-4nlbu54e	178	32	[	[	-LRB-
cord-350019-4nlbu54e	178	33	130	130	CD
cord-350019-4nlbu54e	178	34	]	]	-RRB-
cord-350019-4nlbu54e	178	35	[	[	-LRB-
cord-350019-4nlbu54e	178	36	131	131	CD
cord-350019-4nlbu54e	178	37	]	]	-RRB-
cord-350019-4nlbu54e	178	38	[	[	-LRB-
cord-350019-4nlbu54e	178	39	132	132	CD
cord-350019-4nlbu54e	178	40	]	]	-RRB-
cord-350019-4nlbu54e	178	41	.	.	.
cord-350019-4nlbu54e	179	1	A	a	DT
cord-350019-4nlbu54e	179	2	histone	histone	NN
cord-350019-4nlbu54e	179	3	modification	modification	NN
cord-350019-4nlbu54e	179	4	is	be	VBZ
cord-350019-4nlbu54e	179	5	a	a	DT
cord-350019-4nlbu54e	179	6	covalent	covalent	JJ
cord-350019-4nlbu54e	179	7	post	post	JJ
cord-350019-4nlbu54e	179	8	-	-	JJ
cord-350019-4nlbu54e	179	9	translational	translational	JJ
cord-350019-4nlbu54e	179	10	modification	modification	NN
cord-350019-4nlbu54e	179	11	(	(	-LRB-
cord-350019-4nlbu54e	179	12	PTM	PTM	NNP
cord-350019-4nlbu54e	179	13	)	)	-RRB-
cord-350019-4nlbu54e	179	14	to	to	IN
cord-350019-4nlbu54e	179	15	histone	histone	NN
cord-350019-4nlbu54e	179	16	proteins	protein	NNS
cord-350019-4nlbu54e	179	17	which	which	WDT
cord-350019-4nlbu54e	179	18	includes	include	VBZ
cord-350019-4nlbu54e	179	19	methylation	methylation	NN
cord-350019-4nlbu54e	179	20	,	,	,
cord-350019-4nlbu54e	179	21	phosphorylation	phosphorylation	NN
cord-350019-4nlbu54e	179	22	,	,	,
cord-350019-4nlbu54e	179	23	acetylation	acetylation	NN
cord-350019-4nlbu54e	179	24	,	,	,
cord-350019-4nlbu54e	179	25	ubiquitylation	ubiquitylation	NN
cord-350019-4nlbu54e	179	26	,	,	,
cord-350019-4nlbu54e	179	27	and	and	CC
cord-350019-4nlbu54e	179	28	sumoylation	sumoylation	NN
cord-350019-4nlbu54e	179	29	(	(	-LRB-
cord-350019-4nlbu54e	179	30	reviewed	review	VBN
cord-350019-4nlbu54e	179	31	in	in	IN
cord-350019-4nlbu54e	179	32	[	[	-LRB-
cord-350019-4nlbu54e	179	33	133	133	CD
cord-350019-4nlbu54e	179	34	]	]	-RRB-
cord-350019-4nlbu54e	179	35	)	)	-RRB-
cord-350019-4nlbu54e	179	36	.	.	.
cord-350019-4nlbu54e	180	1	Posttranslational	posttranslational	JJ
cord-350019-4nlbu54e	180	2	histone	histone	NN
cord-350019-4nlbu54e	180	3	modifications	modification	NNS
cord-350019-4nlbu54e	180	4	do	do	VBP
cord-350019-4nlbu54e	180	5	not	not	RB
cord-350019-4nlbu54e	180	6	affect	affect	VB
cord-350019-4nlbu54e	180	7	DNA	dna	NN
cord-350019-4nlbu54e	180	8	nucleotide	nucleotide	JJ
cord-350019-4nlbu54e	180	9	sequence	sequence	NN
cord-350019-4nlbu54e	180	10	but	but	CC
cord-350019-4nlbu54e	180	11	can	can	MD
cord-350019-4nlbu54e	180	12	modify	modify	VB
cord-350019-4nlbu54e	180	13	chromatin	chromatin	NN
cord-350019-4nlbu54e	180	14	availability	availability	NN
cord-350019-4nlbu54e	180	15	to	to	IN
cord-350019-4nlbu54e	180	16	the	the	DT
cord-350019-4nlbu54e	180	17	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	180	18	machinery	machinery	NN
cord-350019-4nlbu54e	180	19	[	[	-LRB-
cord-350019-4nlbu54e	180	20	134	134	CD
cord-350019-4nlbu54e	180	21	]	]	-RRB-
cord-350019-4nlbu54e	180	22	.	.	.
cord-350019-4nlbu54e	181	1	Identifying	identify	VBG
cord-350019-4nlbu54e	181	2	the	the	DT
cord-350019-4nlbu54e	181	3	types	type	NNS
cord-350019-4nlbu54e	181	4	of	of	IN
cord-350019-4nlbu54e	181	5	epigenetic	epigenetic	JJ
cord-350019-4nlbu54e	181	6	histone	histone	NN
cord-350019-4nlbu54e	181	7	marks	mark	NNS
cord-350019-4nlbu54e	181	8	will	will	MD
cord-350019-4nlbu54e	181	9	add	add	VB
cord-350019-4nlbu54e	181	10	additional	additional	JJ
cord-350019-4nlbu54e	181	11	layers	layer	NNS
cord-350019-4nlbu54e	181	12	of	of	IN
cord-350019-4nlbu54e	181	13	understanding	understanding	NN
cord-350019-4nlbu54e	181	14	if	if	IN
cord-350019-4nlbu54e	181	15	the	the	DT
cord-350019-4nlbu54e	181	16	candidate	candidate	NN
cord-350019-4nlbu54e	181	17	is	be	VBZ
cord-350019-4nlbu54e	181	18	active	active	JJ
cord-350019-4nlbu54e	181	19	,	,	,
cord-350019-4nlbu54e	181	20	poised	poised	JJ
cord-350019-4nlbu54e	181	21	,	,	,
cord-350019-4nlbu54e	181	22	silenced	silence	VBN
cord-350019-4nlbu54e	181	23	or	or	CC
cord-350019-4nlbu54e	181	24	an	an	DT
cord-350019-4nlbu54e	181	25	enhancer	enhancer	NN
cord-350019-4nlbu54e	181	26	.	.	.
cord-350019-4nlbu54e	182	1	Many	many	JJ
cord-350019-4nlbu54e	182	2	publicly	publicly	RB
cord-350019-4nlbu54e	182	3	available	available	JJ
cord-350019-4nlbu54e	182	4	datasets	dataset	NNS
cord-350019-4nlbu54e	182	5	provide	provide	VBP
cord-350019-4nlbu54e	182	6	this	this	DT
cord-350019-4nlbu54e	182	7	information	information	NN
cord-350019-4nlbu54e	182	8	outlined	outline	VBN
cord-350019-4nlbu54e	182	9	in	in	IN
cord-350019-4nlbu54e	182	10	Tables	table	NNS
cord-350019-4nlbu54e	182	11	1	1	CD
cord-350019-4nlbu54e	182	12	and	and	CC
cord-350019-4nlbu54e	182	13	2	2	CD
cord-350019-4nlbu54e	182	14	.	.	.
cord-350019-4nlbu54e	183	1	While	while	IN
cord-350019-4nlbu54e	183	2	the	the	DT
cord-350019-4nlbu54e	183	3	examples	example	NNS
cord-350019-4nlbu54e	183	4	we	-PRON-	PRP
cord-350019-4nlbu54e	183	5	outlined	outline	VBD
cord-350019-4nlbu54e	183	6	here	here	RB
cord-350019-4nlbu54e	183	7	are	be	VBP
cord-350019-4nlbu54e	183	8	immune	immune	JJ
cord-350019-4nlbu54e	183	9	focused	focused	JJ
cord-350019-4nlbu54e	183	10	there	there	EX
cord-350019-4nlbu54e	183	11	is	be	VBZ
cord-350019-4nlbu54e	183	12	a	a	DT
cord-350019-4nlbu54e	183	13	vast	vast	JJ
cord-350019-4nlbu54e	183	14	array	array	NN
cord-350019-4nlbu54e	183	15	of	of	IN
cord-350019-4nlbu54e	183	16	additional	additional	JJ
cord-350019-4nlbu54e	183	17	primary	primary	NN
cord-350019-4nlbu54e	183	18	and	and	CC
cord-350019-4nlbu54e	183	19	immortalized	immortalized	JJ
cord-350019-4nlbu54e	183	20	cell	cell	NN
cord-350019-4nlbu54e	183	21	line	line	NN
cord-350019-4nlbu54e	183	22	for	for	IN
cord-350019-4nlbu54e	183	23	every	every	DT
cord-350019-4nlbu54e	183	24	histone	histone	NN
cord-350019-4nlbu54e	183	25	mark	mark	NN
cord-350019-4nlbu54e	183	26	available	available	JJ
cord-350019-4nlbu54e	183	27	through	through	IN
cord-350019-4nlbu54e	183	28	the	the	DT
cord-350019-4nlbu54e	183	29	easily	easily	RB
cord-350019-4nlbu54e	183	30	accessible	accessible	JJ
cord-350019-4nlbu54e	183	31	ENCODE	encode	NN
cord-350019-4nlbu54e	183	32	database	database	NN
cord-350019-4nlbu54e	183	33	[	[	-LRB-
cord-350019-4nlbu54e	183	34	101	101	CD
cord-350019-4nlbu54e	183	35	]	]	-RRB-
cord-350019-4nlbu54e	183	36	.	.	.
cord-350019-4nlbu54e	184	1	Finally	finally	RB
cord-350019-4nlbu54e	184	2	,	,	,
cord-350019-4nlbu54e	184	3	the	the	DT
cord-350019-4nlbu54e	184	4	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	184	5	regulation	regulation	NN
cord-350019-4nlbu54e	184	6	of	of	IN
cord-350019-4nlbu54e	184	7	a	a	DT
cord-350019-4nlbu54e	184	8	lncRNA	lncrna	NN
cord-350019-4nlbu54e	184	9	can	can	MD
cord-350019-4nlbu54e	184	10	be	be	VB
cord-350019-4nlbu54e	184	11	defined	define	VBN
cord-350019-4nlbu54e	184	12	by	by	IN
cord-350019-4nlbu54e	184	13	analyzing	analyze	VBG
cord-350019-4nlbu54e	184	14	the	the	DT
cord-350019-4nlbu54e	184	15	transcription	transcription	NN
cord-350019-4nlbu54e	184	16	factor	factor	NN
cord-350019-4nlbu54e	184	17	(	(	-LRB-
cord-350019-4nlbu54e	184	18	TF	TF	NNP
cord-350019-4nlbu54e	184	19	)	)	-RRB-
cord-350019-4nlbu54e	184	20	motif	motif	NN
cord-350019-4nlbu54e	184	21	's	be	VBZ
cord-350019-4nlbu54e	184	22	that	that	DT
cord-350019-4nlbu54e	184	23	lie	lie	NN
cord-350019-4nlbu54e	184	24	within	within	IN
cord-350019-4nlbu54e	184	25	the	the	DT
cord-350019-4nlbu54e	184	26	predicted	predict	VBN
cord-350019-4nlbu54e	184	27	promoter	promoter	NN
cord-350019-4nlbu54e	184	28	region	region	NN
cord-350019-4nlbu54e	184	29	[	[	-LRB-
cord-350019-4nlbu54e	184	30	135	135	CD
cord-350019-4nlbu54e	184	31	]	]	-RRB-
cord-350019-4nlbu54e	184	32	[	[	-LRB-
cord-350019-4nlbu54e	184	33	136	136	CD
cord-350019-4nlbu54e	184	34	]	]	-RRB-
cord-350019-4nlbu54e	184	35	[	[	-LRB-
cord-350019-4nlbu54e	184	36	137	137	CD
cord-350019-4nlbu54e	184	37	]	]	-RRB-
cord-350019-4nlbu54e	184	38	.	.	.
cord-350019-4nlbu54e	185	1	RNAReg2.0	RNAReg2.0	NNPS
cord-350019-4nlbu54e	185	2	[	[	-LRB-
cord-350019-4nlbu54e	185	3	138	138	CD
cord-350019-4nlbu54e	185	4	]	]	-RRB-
cord-350019-4nlbu54e	185	5	or	or	CC
cord-350019-4nlbu54e	185	6	HOMER	HOMER	NNP
cord-350019-4nlbu54e	185	7	[	[	-LRB-
cord-350019-4nlbu54e	185	8	139	139	CD
cord-350019-4nlbu54e	185	9	,	,	,
cord-350019-4nlbu54e	185	10	140	140	CD
cord-350019-4nlbu54e	185	11	]	]	-RRB-
cord-350019-4nlbu54e	185	12	are	be	VBP
cord-350019-4nlbu54e	185	13	useful	useful	JJ
cord-350019-4nlbu54e	185	14	tools	tool	NNS
cord-350019-4nlbu54e	185	15	to	to	TO
cord-350019-4nlbu54e	185	16	predict	predict	VB
cord-350019-4nlbu54e	185	17	TF	TF	NNP
cord-350019-4nlbu54e	185	18	binding	binding	NN
cord-350019-4nlbu54e	185	19	sites	site	NNS
cord-350019-4nlbu54e	185	20	by	by	IN
cord-350019-4nlbu54e	185	21	motif	motif	NN
cord-350019-4nlbu54e	185	22	analysis	analysis	NN
cord-350019-4nlbu54e	185	23	.	.	.
cord-350019-4nlbu54e	186	1	TF	TF	NNP
cord-350019-4nlbu54e	186	2	motifs	motif	NNS
cord-350019-4nlbu54e	186	3	can	can	MD
cord-350019-4nlbu54e	186	4	be	be	VB
cord-350019-4nlbu54e	186	5	indicative	indicative	JJ
cord-350019-4nlbu54e	186	6	of	of	IN
cord-350019-4nlbu54e	186	7	biological	biological	JJ
cord-350019-4nlbu54e	186	8	pathway	pathway	NN
cord-350019-4nlbu54e	186	9	regulation	regulation	NN
cord-350019-4nlbu54e	186	10	indicating	indicate	VBG
cord-350019-4nlbu54e	186	11	when	when	WRB
cord-350019-4nlbu54e	186	12	a	a	DT
cord-350019-4nlbu54e	186	13	gene	gene	NN
cord-350019-4nlbu54e	186	14	is	be	VBZ
cord-350019-4nlbu54e	186	15	expressed	express	VBN
cord-350019-4nlbu54e	186	16	.	.	.
cord-350019-4nlbu54e	187	1	These	these	DT
cord-350019-4nlbu54e	187	2	findings	finding	NNS
cord-350019-4nlbu54e	187	3	of	of	IN
cord-350019-4nlbu54e	187	4	predicted	predict	VBN
cord-350019-4nlbu54e	187	5	TF	TF	NNP
cord-350019-4nlbu54e	187	6	can	can	MD
cord-350019-4nlbu54e	187	7	then	then	RB
cord-350019-4nlbu54e	187	8	be	be	VB
cord-350019-4nlbu54e	187	9	put	put	VBN
cord-350019-4nlbu54e	187	10	into	into	IN
cord-350019-4nlbu54e	187	11	a	a	DT
cord-350019-4nlbu54e	187	12	gene	gene	NN
cord-350019-4nlbu54e	187	13	ontology	ontology	NN
cord-350019-4nlbu54e	187	14	tool	tool	NN
cord-350019-4nlbu54e	187	15	(	(	-LRB-
cord-350019-4nlbu54e	187	16	PANTHER	PANTHER	NNP
cord-350019-4nlbu54e	187	17	or	or	CC
cord-350019-4nlbu54e	187	18	DAVID	DAVID	NNP
cord-350019-4nlbu54e	187	19	)	)	-RRB-
cord-350019-4nlbu54e	187	20	to	to	TO
cord-350019-4nlbu54e	187	21	assess	assess	VB
cord-350019-4nlbu54e	187	22	how	how	WRB
cord-350019-4nlbu54e	187	23	a	a	DT
cord-350019-4nlbu54e	187	24	candidate	candidate	NN
cord-350019-4nlbu54e	187	25	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	187	26	is	be	VBZ
cord-350019-4nlbu54e	187	27	transcriptionally	transcriptionally	RB
cord-350019-4nlbu54e	187	28	regulated	regulate	VBN
cord-350019-4nlbu54e	187	29	.	.	.
cord-350019-4nlbu54e	188	1	For	for	IN
cord-350019-4nlbu54e	188	2	instance	instance	NN
cord-350019-4nlbu54e	188	3	,	,	,
cord-350019-4nlbu54e	188	4	the	the	DT
cord-350019-4nlbu54e	188	5	presence	presence	NN
cord-350019-4nlbu54e	188	6	of	of	IN
cord-350019-4nlbu54e	188	7	pioneering	pioneer	VBG
cord-350019-4nlbu54e	188	8	transcription	transcription	NN
cord-350019-4nlbu54e	188	9	factors	factor	NNS
cord-350019-4nlbu54e	188	10	could	could	MD
cord-350019-4nlbu54e	188	11	provide	provide	VB
cord-350019-4nlbu54e	188	12	information	information	NN
cord-350019-4nlbu54e	188	13	on	on	IN
cord-350019-4nlbu54e	188	14	the	the	DT
cord-350019-4nlbu54e	188	15	cell	cell	NN
cord-350019-4nlbu54e	188	16	type	type	NN
cord-350019-4nlbu54e	188	17	specificity	specificity	NN
cord-350019-4nlbu54e	188	18	of	of	IN
cord-350019-4nlbu54e	188	19	a	a	DT
cord-350019-4nlbu54e	188	20	lncRNA	lncrna	NN
cord-350019-4nlbu54e	188	21	.	.	.
cord-350019-4nlbu54e	189	1	On	on	IN
cord-350019-4nlbu54e	189	2	the	the	DT
cord-350019-4nlbu54e	189	3	other	other	JJ
cord-350019-4nlbu54e	189	4	hand	hand	NN
cord-350019-4nlbu54e	189	5	,	,	,
cord-350019-4nlbu54e	189	6	if	if	IN
cord-350019-4nlbu54e	189	7	the	the	DT
cord-350019-4nlbu54e	189	8	promoter	promoter	NN
cord-350019-4nlbu54e	189	9	motifs	motif	NNS
cord-350019-4nlbu54e	189	10	are	be	VBP
cord-350019-4nlbu54e	189	11	enriched	enrich	VBN
cord-350019-4nlbu54e	189	12	for	for	IN
cord-350019-4nlbu54e	189	13	p65	p65	NN
cord-350019-4nlbu54e	189	14	,	,	,
cord-350019-4nlbu54e	189	15	Interferon	Interferon	NNP
cord-350019-4nlbu54e	189	16	Response	Response	NNP
cord-350019-4nlbu54e	189	17	Factors	Factors	NNP
cord-350019-4nlbu54e	189	18	(	(	-LRB-
cord-350019-4nlbu54e	189	19	IRFs	IRFs	NNP
cord-350019-4nlbu54e	189	20	)	)	-RRB-
cord-350019-4nlbu54e	189	21	or	or	CC
cord-350019-4nlbu54e	189	22	Activating	Activating	NNP
cord-350019-4nlbu54e	189	23	Transcription	Transcription	NNP
cord-350019-4nlbu54e	189	24	Factors	Factors	NNP
cord-350019-4nlbu54e	189	25	(	(	-LRB-
cord-350019-4nlbu54e	189	26	ATFs	atf	NNS
cord-350019-4nlbu54e	189	27	)	)	-RRB-
cord-350019-4nlbu54e	190	1	this	this	DT
cord-350019-4nlbu54e	190	2	would	would	MD
cord-350019-4nlbu54e	190	3	be	be	VB
cord-350019-4nlbu54e	190	4	indicative	indicative	JJ
cord-350019-4nlbu54e	190	5	of	of	IN
cord-350019-4nlbu54e	190	6	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	190	7	specific	specific	JJ
cord-350019-4nlbu54e	190	8	expression	expression	NN
cord-350019-4nlbu54e	190	9	.	.	.
cord-350019-4nlbu54e	191	1	This	this	DT
cord-350019-4nlbu54e	191	2	finding	finding	NN
cord-350019-4nlbu54e	191	3	can	can	MD
cord-350019-4nlbu54e	191	4	be	be	VB
cord-350019-4nlbu54e	191	5	further	further	RB
cord-350019-4nlbu54e	191	6	supported	support	VBN
cord-350019-4nlbu54e	191	7	by	by	IN
cord-350019-4nlbu54e	191	8	Chromatin	Chromatin	NNP
cord-350019-4nlbu54e	191	9	immunoprecipitation	immunoprecipitation	NN
cord-350019-4nlbu54e	191	10	(	(	-LRB-
cord-350019-4nlbu54e	191	11	ChIP	chip	NN
cord-350019-4nlbu54e	191	12	)	)	-RRB-
cord-350019-4nlbu54e	191	13	sequencing	sequencing	NN
cord-350019-4nlbu54e	191	14	data	data	NN
cord-350019-4nlbu54e	191	15	sets	set	NNS
cord-350019-4nlbu54e	191	16	from	from	IN
cord-350019-4nlbu54e	191	17	a	a	DT
cord-350019-4nlbu54e	191	18	multitude	multitude	NN
cord-350019-4nlbu54e	191	19	of	of	IN
cord-350019-4nlbu54e	191	20	labs	lab	NNS
cord-350019-4nlbu54e	191	21	,	,	,
cord-350019-4nlbu54e	191	22	as	as	RB
cord-350019-4nlbu54e	191	23	well	well	RB
cord-350019-4nlbu54e	191	24	as	as	IN
cord-350019-4nlbu54e	191	25	data	datum	NNS
cord-350019-4nlbu54e	191	26	from	from	IN
cord-350019-4nlbu54e	191	27	the	the	DT
cord-350019-4nlbu54e	191	28	ENCODE	encode	NN
cord-350019-4nlbu54e	191	29	project	project	NN
cord-350019-4nlbu54e	191	30	(	(	-LRB-
cord-350019-4nlbu54e	191	31	outlined	outline	VBN
cord-350019-4nlbu54e	191	32	in	in	IN
cord-350019-4nlbu54e	191	33	Tables	table	NNS
cord-350019-4nlbu54e	191	34	1	1	CD
cord-350019-4nlbu54e	191	35	and	and	CC
cord-350019-4nlbu54e	191	36	2	2	CD
cord-350019-4nlbu54e	191	37	)	)	-RRB-
cord-350019-4nlbu54e	191	38	.	.	.
cord-350019-4nlbu54e	192	1	The	the	DT
cord-350019-4nlbu54e	192	2	categorization	categorization	NN
cord-350019-4nlbu54e	192	3	of	of	IN
cord-350019-4nlbu54e	192	4	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	192	5	as	as	IN
cord-350019-4nlbu54e	192	6	"	"	``
cord-350019-4nlbu54e	192	7	noncoding	noncoding	JJ
cord-350019-4nlbu54e	192	8	"	"	''
cord-350019-4nlbu54e	192	9	is	be	VBZ
cord-350019-4nlbu54e	192	10	initially	initially	RB
cord-350019-4nlbu54e	192	11	determined	determine	VBN
cord-350019-4nlbu54e	192	12	bioinformatically	bioinformatically	RB
cord-350019-4nlbu54e	192	13	using	use	VBG
cord-350019-4nlbu54e	192	14	the	the	DT
cord-350019-4nlbu54e	192	15	arbitrary	arbitrary	JJ
cord-350019-4nlbu54e	192	16	cut	cut	NN
cord-350019-4nlbu54e	192	17	-	-	HYPH
cord-350019-4nlbu54e	192	18	off	off	NN
cord-350019-4nlbu54e	192	19	of	of	IN
cord-350019-4nlbu54e	192	20	<	<	NNP
cord-350019-4nlbu54e	192	21	100	100	CD
cord-350019-4nlbu54e	192	22	codons	codon	NNS
cord-350019-4nlbu54e	192	23	[	[	-LRB-
cord-350019-4nlbu54e	192	24	141	141	CD
cord-350019-4nlbu54e	192	25	]	]	-RRB-
cord-350019-4nlbu54e	192	26	.	.	.
cord-350019-4nlbu54e	193	1	This	this	DT
cord-350019-4nlbu54e	193	2	leaves	leave	VBZ
cord-350019-4nlbu54e	193	3	the	the	DT
cord-350019-4nlbu54e	193	4	possibility	possibility	NN
cord-350019-4nlbu54e	193	5	that	that	IN
cord-350019-4nlbu54e	193	6	some	some	DT
cord-350019-4nlbu54e	193	7	lncRNAs	lncrnas	VBP
cord-350019-4nlbu54e	193	8	may	may	MD
cord-350019-4nlbu54e	193	9	be	be	VB
cord-350019-4nlbu54e	193	10	mRNAs	mrnas	ADD
cord-350019-4nlbu54e	193	11	.	.	.
cord-350019-4nlbu54e	194	1	Therefore	therefore	RB
cord-350019-4nlbu54e	194	2	,	,	,
cord-350019-4nlbu54e	194	3	one	one	CD
cord-350019-4nlbu54e	194	4	of	of	IN
cord-350019-4nlbu54e	194	5	the	the	DT
cord-350019-4nlbu54e	194	6	first	first	JJ
cord-350019-4nlbu54e	194	7	steps	step	NNS
cord-350019-4nlbu54e	194	8	in	in	IN
cord-350019-4nlbu54e	194	9	characterizing	characterize	VBG
cord-350019-4nlbu54e	194	10	a	a	DT
cord-350019-4nlbu54e	194	11	candidate	candidate	NN
cord-350019-4nlbu54e	194	12	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	194	13	is	be	VBZ
cord-350019-4nlbu54e	194	14	to	to	TO
cord-350019-4nlbu54e	194	15	confirm	confirm	VB
cord-350019-4nlbu54e	194	16	that	that	IN
cord-350019-4nlbu54e	194	17	it	-PRON-	PRP
cord-350019-4nlbu54e	194	18	is	be	VBZ
cord-350019-4nlbu54e	194	19	noncoding	noncoding	JJ
cord-350019-4nlbu54e	194	20	.	.	.
cord-350019-4nlbu54e	195	1	For	for	IN
cord-350019-4nlbu54e	195	2	example	example	NN
cord-350019-4nlbu54e	195	3	,	,	,
cord-350019-4nlbu54e	195	4	in	in	IN
cord-350019-4nlbu54e	195	5	Drosophila	Drosophila	NNP
cord-350019-4nlbu54e	195	6	,	,	,
cord-350019-4nlbu54e	195	7	a	a	DT
cord-350019-4nlbu54e	195	8	gene	gene	NN
cord-350019-4nlbu54e	195	9	annotated	annotate	VBN
cord-350019-4nlbu54e	195	10	as	as	IN
cord-350019-4nlbu54e	195	11	a	a	DT
cord-350019-4nlbu54e	195	12	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	195	13	FBgn0087003	fbgn0087003	NN
cord-350019-4nlbu54e	195	14	,	,	,
cord-350019-4nlbu54e	195	15	was	be	VBD
cord-350019-4nlbu54e	195	16	shown	show	VBN
cord-350019-4nlbu54e	195	17	to	to	TO
cord-350019-4nlbu54e	195	18	encode	encode	VB
cord-350019-4nlbu54e	195	19	multiple	multiple	JJ
cord-350019-4nlbu54e	195	20	small	small	JJ
cord-350019-4nlbu54e	195	21	~	~	CD
cord-350019-4nlbu54e	195	22	ten	ten	CD
cord-350019-4nlbu54e	195	23	amino	amino	NN
cord-350019-4nlbu54e	195	24	acid	acid	NN
cord-350019-4nlbu54e	195	25	peptides	peptide	NNS
cord-350019-4nlbu54e	195	26	critical	critical	JJ
cord-350019-4nlbu54e	195	27	for	for	IN
cord-350019-4nlbu54e	195	28	development	development	NN
cord-350019-4nlbu54e	195	29	[	[	-LRB-
cord-350019-4nlbu54e	195	30	142	142	CD
cord-350019-4nlbu54e	195	31	]	]	-RRB-
cord-350019-4nlbu54e	195	32	.	.	.
cord-350019-4nlbu54e	196	1	The	the	DT
cord-350019-4nlbu54e	196	2	discovery	discovery	NN
cord-350019-4nlbu54e	196	3	of	of	IN
cord-350019-4nlbu54e	196	4	these	these	DT
cord-350019-4nlbu54e	196	5	germline	germline	NN
cord-350019-4nlbu54e	196	6	-	-	HYPH
cord-350019-4nlbu54e	196	7	encoded	encode	VBN
cord-350019-4nlbu54e	196	8	biologically	biologically	RB
cord-350019-4nlbu54e	196	9	active	active	JJ
cord-350019-4nlbu54e	196	10	peptides	peptide	NNS
cord-350019-4nlbu54e	196	11	has	have	VBZ
cord-350019-4nlbu54e	196	12	opened	open	VBN
cord-350019-4nlbu54e	196	13	the	the	DT
cord-350019-4nlbu54e	196	14	door	door	NN
cord-350019-4nlbu54e	196	15	into	into	IN
cord-350019-4nlbu54e	196	16	new	new	JJ
cord-350019-4nlbu54e	196	17	and	and	CC
cord-350019-4nlbu54e	196	18	exciting	exciting	JJ
cord-350019-4nlbu54e	196	19	levels	level	NNS
cord-350019-4nlbu54e	196	20	of	of	IN
cord-350019-4nlbu54e	196	21	regulation	regulation	NN
cord-350019-4nlbu54e	196	22	.	.	.
cord-350019-4nlbu54e	197	1	However	however	RB
cord-350019-4nlbu54e	197	2	,	,	,
cord-350019-4nlbu54e	197	3	this	this	DT
cord-350019-4nlbu54e	197	4	discovery	discovery	NN
cord-350019-4nlbu54e	197	5	also	also	RB
cord-350019-4nlbu54e	197	6	shows	show	VBZ
cord-350019-4nlbu54e	197	7	that	that	IN
cord-350019-4nlbu54e	197	8	we	-PRON-	PRP
cord-350019-4nlbu54e	197	9	should	should	MD
cord-350019-4nlbu54e	197	10	be	be	VB
cord-350019-4nlbu54e	197	11	cautious	cautious	JJ
cord-350019-4nlbu54e	197	12	when	when	WRB
cord-350019-4nlbu54e	197	13	characterizing	characterize	VBG
cord-350019-4nlbu54e	197	14	a	a	DT
cord-350019-4nlbu54e	197	15	lncRNA	lncrna	NN
cord-350019-4nlbu54e	197	16	to	to	TO
cord-350019-4nlbu54e	197	17	confirm	confirm	VB
cord-350019-4nlbu54e	197	18	that	that	IN
cord-350019-4nlbu54e	197	19	indeed	indeed	RB
cord-350019-4nlbu54e	197	20	they	-PRON-	PRP
cord-350019-4nlbu54e	197	21	are	be	VBP
cord-350019-4nlbu54e	197	22	noncoding	noncoding	JJ
cord-350019-4nlbu54e	197	23	.	.	.
cord-350019-4nlbu54e	198	1	Several	several	JJ
cord-350019-4nlbu54e	198	2	bioinformatic	bioinformatic	JJ
cord-350019-4nlbu54e	198	3	tools	tool	NNS
cord-350019-4nlbu54e	198	4	exist	exist	VBP
cord-350019-4nlbu54e	198	5	for	for	IN
cord-350019-4nlbu54e	198	6	predicting	predict	VBG
cord-350019-4nlbu54e	198	7	small	small	JJ
cord-350019-4nlbu54e	198	8	ORFs	orf	NNS
cord-350019-4nlbu54e	198	9	(	(	-LRB-
cord-350019-4nlbu54e	198	10	smORF	smorf	JJ
cord-350019-4nlbu54e	198	11	)	)	-RRB-
cord-350019-4nlbu54e	198	12	but	but	CC
cord-350019-4nlbu54e	198	13	have	have	VBP
cord-350019-4nlbu54e	198	14	noted	note	VBN
cord-350019-4nlbu54e	198	15	that	that	IN
cord-350019-4nlbu54e	198	16	the	the	DT
cord-350019-4nlbu54e	198	17	predictive	predictive	JJ
cord-350019-4nlbu54e	198	18	ability	ability	NN
cord-350019-4nlbu54e	198	19	for	for	IN
cord-350019-4nlbu54e	198	20	smaller	small	JJR
cord-350019-4nlbu54e	198	21	ORF	ORF	NNP
cord-350019-4nlbu54e	198	22	size	size	NN
cord-350019-4nlbu54e	198	23	is	be	VBZ
cord-350019-4nlbu54e	198	24	in	in	IN
cord-350019-4nlbu54e	198	25	general	general	JJ
cord-350019-4nlbu54e	198	26	very	very	RB
cord-350019-4nlbu54e	198	27	poor	poor	JJ
cord-350019-4nlbu54e	198	28	[	[	-LRB-
cord-350019-4nlbu54e	198	29	143	143	CD
cord-350019-4nlbu54e	198	30	]	]	-RRB-
cord-350019-4nlbu54e	198	31	.	.	.
cord-350019-4nlbu54e	198	32	PhyloCSF	PhyloCSF	NNS
cord-350019-4nlbu54e	199	1	uses	use	VBZ
cord-350019-4nlbu54e	199	2	codon	codon	NN
cord-350019-4nlbu54e	199	3	substitution	substitution	NN
cord-350019-4nlbu54e	199	4	frequency	frequency	NN
cord-350019-4nlbu54e	199	5	,	,	,
cord-350019-4nlbu54e	199	6	together	together	RB
cord-350019-4nlbu54e	199	7	with	with	IN
cord-350019-4nlbu54e	199	8	conservation	conservation	NN
cord-350019-4nlbu54e	199	9	across	across	IN
cord-350019-4nlbu54e	199	10	multiple	multiple	JJ
cord-350019-4nlbu54e	199	11	species	specie	NNS
cord-350019-4nlbu54e	199	12	,	,	,
cord-350019-4nlbu54e	199	13	to	to	TO
cord-350019-4nlbu54e	199	14	provide	provide	VB
cord-350019-4nlbu54e	199	15	a	a	DT
cord-350019-4nlbu54e	199	16	score	score	NN
cord-350019-4nlbu54e	199	17	metric	metric	NN
cord-350019-4nlbu54e	199	18	that	that	WDT
cord-350019-4nlbu54e	199	19	can	can	MD
cord-350019-4nlbu54e	199	20	be	be	VB
cord-350019-4nlbu54e	199	21	used	use	VBN
cord-350019-4nlbu54e	199	22	to	to	TO
cord-350019-4nlbu54e	199	23	determine	determine	VB
cord-350019-4nlbu54e	199	24	the	the	DT
cord-350019-4nlbu54e	199	25	presence	presence	NN
cord-350019-4nlbu54e	199	26	of	of	IN
cord-350019-4nlbu54e	199	27	a	a	DT
cord-350019-4nlbu54e	199	28	conserved	conserve	VBN
cord-350019-4nlbu54e	199	29	ORF	ORF	NNP
cord-350019-4nlbu54e	199	30	[	[	-LRB-
cord-350019-4nlbu54e	199	31	113	113	CD
cord-350019-4nlbu54e	199	32	]	]	-RRB-
cord-350019-4nlbu54e	199	33	.	.	.
cord-350019-4nlbu54e	200	1	Other	other	JJ
cord-350019-4nlbu54e	200	2	approaches	approach	NNS
cord-350019-4nlbu54e	200	3	have	have	VBP
cord-350019-4nlbu54e	200	4	sought	seek	VBN
cord-350019-4nlbu54e	200	5	to	to	TO
cord-350019-4nlbu54e	200	6	identify	identify	VB
cord-350019-4nlbu54e	200	7	novel	novel	JJ
cord-350019-4nlbu54e	200	8	small	small	JJ
cord-350019-4nlbu54e	200	9	peptides	peptide	NNS
cord-350019-4nlbu54e	200	10	using	use	VBG
cord-350019-4nlbu54e	200	11	mass	mass	NN
cord-350019-4nlbu54e	200	12	spectrometry	spectrometry	NN
cord-350019-4nlbu54e	200	13	.	.	.
cord-350019-4nlbu54e	201	1	However	however	RB
cord-350019-4nlbu54e	201	2	,	,	,
cord-350019-4nlbu54e	201	3	a	a	DT
cord-350019-4nlbu54e	201	4	major	major	JJ
cord-350019-4nlbu54e	201	5	challenge	challenge	NN
cord-350019-4nlbu54e	201	6	is	be	VBZ
cord-350019-4nlbu54e	201	7	determining	determine	VBG
cord-350019-4nlbu54e	201	8	whether	whether	IN
cord-350019-4nlbu54e	201	9	the	the	DT
cord-350019-4nlbu54e	201	10	peptides	peptide	NNS
cord-350019-4nlbu54e	201	11	identified	identify	VBN
cord-350019-4nlbu54e	201	12	correspond	correspond	VBP
cord-350019-4nlbu54e	201	13	to	to	IN
cord-350019-4nlbu54e	201	14	novel	novel	NN
cord-350019-4nlbu54e	201	15	smORFs	smORFs	NNP
cord-350019-4nlbu54e	201	16	or	or	CC
cord-350019-4nlbu54e	201	17	represent	represent	VB
cord-350019-4nlbu54e	201	18	degraded	degraded	JJ
cord-350019-4nlbu54e	201	19	intermediates	intermediate	NNS
cord-350019-4nlbu54e	201	20	of	of	IN
cord-350019-4nlbu54e	201	21	larger	large	JJR
cord-350019-4nlbu54e	201	22	proteins	protein	NNS
cord-350019-4nlbu54e	201	23	[	[	-LRB-
cord-350019-4nlbu54e	201	24	144	144	CD
cord-350019-4nlbu54e	201	25	]	]	-RRB-
cord-350019-4nlbu54e	201	26	.	.	.
cord-350019-4nlbu54e	202	1	The	the	DT
cord-350019-4nlbu54e	202	2	development	development	NN
cord-350019-4nlbu54e	202	3	of	of	IN
cord-350019-4nlbu54e	202	4	ribosomal	ribosomal	JJ
cord-350019-4nlbu54e	202	5	foot	foot	NN
cord-350019-4nlbu54e	202	6	-	-	HYPH
cord-350019-4nlbu54e	202	7	printing	printing	NN
cord-350019-4nlbu54e	202	8	coupled	couple	VBN
cord-350019-4nlbu54e	202	9	to	to	IN
cord-350019-4nlbu54e	202	10	next	next	JJ
cord-350019-4nlbu54e	202	11	-	-	HYPH
cord-350019-4nlbu54e	202	12	generation	generation	NN
cord-350019-4nlbu54e	202	13	sequencing	sequencing	NN
cord-350019-4nlbu54e	202	14	(	(	-LRB-
cord-350019-4nlbu54e	202	15	ribo	ribo	NN
cord-350019-4nlbu54e	202	16	-	-	HYPH
cord-350019-4nlbu54e	202	17	seq	seq	NNP
cord-350019-4nlbu54e	202	18	)	)	-RRB-
cord-350019-4nlbu54e	202	19	has	have	VBZ
cord-350019-4nlbu54e	202	20	provided	provide	VBN
cord-350019-4nlbu54e	202	21	a	a	DT
cord-350019-4nlbu54e	202	22	powerful	powerful	JJ
cord-350019-4nlbu54e	202	23	quantitative	quantitative	JJ
cord-350019-4nlbu54e	202	24	method	method	NN
cord-350019-4nlbu54e	202	25	for	for	IN
cord-350019-4nlbu54e	202	26	assessing	assess	VBG
cord-350019-4nlbu54e	202	27	global	global	JJ
cord-350019-4nlbu54e	202	28	translation	translation	NN
cord-350019-4nlbu54e	202	29	[	[	-LRB-
cord-350019-4nlbu54e	202	30	145	145	CD
cord-350019-4nlbu54e	202	31	,	,	,
cord-350019-4nlbu54e	202	32	146	146	CD
cord-350019-4nlbu54e	202	33	]	]	-RRB-
cord-350019-4nlbu54e	202	34	.	.	.
cord-350019-4nlbu54e	203	1	While	while	IN
cord-350019-4nlbu54e	203	2	ribosome	ribosome	NN
cord-350019-4nlbu54e	203	3	profiling	profiling	NN
cord-350019-4nlbu54e	203	4	allows	allow	VBZ
cord-350019-4nlbu54e	203	5	for	for	IN
cord-350019-4nlbu54e	203	6	ribosome	ribosome	NN
cord-350019-4nlbu54e	203	7	nuclease	nuclease	NN
cord-350019-4nlbu54e	203	8	-	-	HYPH
cord-350019-4nlbu54e	203	9	protected	protect	VBN
cord-350019-4nlbu54e	203	10	RNA	rna	NN
cord-350019-4nlbu54e	203	11	fragments	fragment	NNS
cord-350019-4nlbu54e	203	12	to	to	TO
cord-350019-4nlbu54e	203	13	be	be	VB
cord-350019-4nlbu54e	203	14	mapped	map	VBN
cord-350019-4nlbu54e	203	15	to	to	IN
cord-350019-4nlbu54e	203	16	transcripts	transcript	NNS
cord-350019-4nlbu54e	203	17	to	to	TO
cord-350019-4nlbu54e	203	18	enable	enable	VB
cord-350019-4nlbu54e	203	19	quantitative	quantitative	JJ
cord-350019-4nlbu54e	203	20	measurement	measurement	NN
cord-350019-4nlbu54e	203	21	of	of	IN
cord-350019-4nlbu54e	203	22	the	the	DT
cord-350019-4nlbu54e	203	23	translation	translation	NN
cord-350019-4nlbu54e	203	24	efficiency	efficiency	NN
cord-350019-4nlbu54e	203	25	[	[	-LRB-
cord-350019-4nlbu54e	203	26	146	146	CD
cord-350019-4nlbu54e	203	27	]	]	-RRB-
cord-350019-4nlbu54e	203	28	.	.	.
cord-350019-4nlbu54e	204	1	In	in	IN
cord-350019-4nlbu54e	204	2	addition	addition	NN
cord-350019-4nlbu54e	204	3	,	,	,
cord-350019-4nlbu54e	204	4	to	to	IN
cord-350019-4nlbu54e	204	5	mapping	mapping	NN
cord-350019-4nlbu54e	204	6	ORFs	ORFs	NNP
cord-350019-4nlbu54e	204	7	,	,	,
cord-350019-4nlbu54e	204	8	ribo	ribo	NN
cord-350019-4nlbu54e	204	9	-	-	HYPH
cord-350019-4nlbu54e	204	10	seq	seq	NN
cord-350019-4nlbu54e	204	11	can	can	MD
cord-350019-4nlbu54e	204	12	be	be	VB
cord-350019-4nlbu54e	204	13	performed	perform	VBN
cord-350019-4nlbu54e	204	14	with	with	IN
cord-350019-4nlbu54e	204	15	a	a	DT
cord-350019-4nlbu54e	204	16	drug	drug	NN
cord-350019-4nlbu54e	204	17	that	that	WDT
cord-350019-4nlbu54e	204	18	stalls	stall	NNS
cord-350019-4nlbu54e	204	19	ribosomes	ribosomes	VBP
cord-350019-4nlbu54e	204	20	at	at	IN
cord-350019-4nlbu54e	204	21	the	the	DT
cord-350019-4nlbu54e	204	22	start	start	NN
cord-350019-4nlbu54e	204	23	codon	codon	NN
cord-350019-4nlbu54e	204	24	to	to	IN
cord-350019-4nlbu54e	204	25	globally	globally	RB
cord-350019-4nlbu54e	204	26	map	map	VB
cord-350019-4nlbu54e	204	27	translation	translation	NN
cord-350019-4nlbu54e	204	28	start	start	NN
cord-350019-4nlbu54e	204	29	sites	site	NNS
cord-350019-4nlbu54e	204	30	-	-	:
cord-350019-4nlbu54e	204	31	this	this	DT
cord-350019-4nlbu54e	204	32	revealed	reveal	VBD
cord-350019-4nlbu54e	204	33	significant	significant	JJ
cord-350019-4nlbu54e	204	34	numbers	number	NNS
cord-350019-4nlbu54e	204	35	of	of	IN
cord-350019-4nlbu54e	204	36	non	non	JJ
cord-350019-4nlbu54e	204	37	-	-	JJ
cord-350019-4nlbu54e	204	38	canonical	canonical	JJ
cord-350019-4nlbu54e	204	39	translation	translation	NN
cord-350019-4nlbu54e	204	40	initiation	initiation	NN
cord-350019-4nlbu54e	204	41	from	from	IN
cord-350019-4nlbu54e	204	42	CTG	CTG	NNP
cord-350019-4nlbu54e	204	43	codons	codon	NNS
cord-350019-4nlbu54e	204	44	[	[	-LRB-
cord-350019-4nlbu54e	204	45	146	146	CD
cord-350019-4nlbu54e	204	46	]	]	-RRB-
cord-350019-4nlbu54e	204	47	.	.	.
cord-350019-4nlbu54e	205	1	Riboseq	Riboseq	NNP
cord-350019-4nlbu54e	205	2	has	have	VBZ
cord-350019-4nlbu54e	205	3	also	also	RB
cord-350019-4nlbu54e	205	4	found	find	VBN
cord-350019-4nlbu54e	205	5	that	that	IN
cord-350019-4nlbu54e	205	6	many	many	JJ
cord-350019-4nlbu54e	205	7	lncRNAs	lncRNAs	NNPS
cord-350019-4nlbu54e	205	8	appear	appear	VBP
cord-350019-4nlbu54e	205	9	to	to	TO
cord-350019-4nlbu54e	205	10	be	be	VB
cord-350019-4nlbu54e	205	11	translated	translate	VBN
cord-350019-4nlbu54e	205	12	,	,	,
cord-350019-4nlbu54e	205	13	raising	raise	VBG
cord-350019-4nlbu54e	205	14	the	the	DT
cord-350019-4nlbu54e	205	15	possibility	possibility	NN
cord-350019-4nlbu54e	205	16	that	that	IN
cord-350019-4nlbu54e	205	17	some	some	DT
cord-350019-4nlbu54e	205	18	of	of	IN
cord-350019-4nlbu54e	205	19	these	these	DT
cord-350019-4nlbu54e	205	20	transcripts	transcript	NNS
cord-350019-4nlbu54e	205	21	could	could	MD
cord-350019-4nlbu54e	205	22	be	be	VB
cord-350019-4nlbu54e	205	23	producing	produce	VBG
cord-350019-4nlbu54e	205	24	small	small	JJ
cord-350019-4nlbu54e	205	25	peptides	peptide	NNS
cord-350019-4nlbu54e	205	26	[	[	-LRB-
cord-350019-4nlbu54e	205	27	145	145	CD
cord-350019-4nlbu54e	205	28	]	]	-RRB-
cord-350019-4nlbu54e	205	29	.	.	.
cord-350019-4nlbu54e	206	1	Guttman	Guttman	NNP
cord-350019-4nlbu54e	206	2	et	et	NNP
cord-350019-4nlbu54e	206	3	al	al	NNP
cord-350019-4nlbu54e	206	4	.	.	NNP
cord-350019-4nlbu54e	206	5	developed	develop	VBD
cord-350019-4nlbu54e	206	6	the	the	DT
cord-350019-4nlbu54e	206	7	ribosome	ribosome	NN
cord-350019-4nlbu54e	206	8	release	release	NN
cord-350019-4nlbu54e	206	9	score	score	NN
cord-350019-4nlbu54e	206	10	metric	metric	JJ
cord-350019-4nlbu54e	206	11	as	as	IN
cord-350019-4nlbu54e	206	12	part	part	NN
cord-350019-4nlbu54e	206	13	of	of	IN
cord-350019-4nlbu54e	206	14	the	the	DT
cord-350019-4nlbu54e	206	15	ribosome	ribosome	NN
cord-350019-4nlbu54e	206	16	profiling	profiling	NN
cord-350019-4nlbu54e	206	17	analysis	analysis	NN
cord-350019-4nlbu54e	206	18	pipeline	pipeline	NN
cord-350019-4nlbu54e	206	19	to	to	IN
cord-350019-4nlbu54e	206	20	more	more	RBR
cord-350019-4nlbu54e	206	21	accurately	accurately	RB
cord-350019-4nlbu54e	206	22	predict	predict	VB
cord-350019-4nlbu54e	206	23	translational	translational	JJ
cord-350019-4nlbu54e	206	24	efficiency	efficiency	NN
cord-350019-4nlbu54e	206	25	.	.	.
cord-350019-4nlbu54e	207	1	Their	-PRON-	PRP$
cord-350019-4nlbu54e	207	2	findings	finding	NNS
cord-350019-4nlbu54e	207	3	show	show	VBP
cord-350019-4nlbu54e	207	4	that	that	IN
cord-350019-4nlbu54e	207	5	ribosome	ribosome	NN
cord-350019-4nlbu54e	207	6	occupancy	occupancy	NN
cord-350019-4nlbu54e	207	7	of	of	IN
cord-350019-4nlbu54e	207	8	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	207	9	and	and	CC
cord-350019-4nlbu54e	207	10	5′UTRs	5′utrs	CD
cord-350019-4nlbu54e	207	11	does	do	VBZ
cord-350019-4nlbu54e	207	12	not	not	RB
cord-350019-4nlbu54e	207	13	always	always	RB
cord-350019-4nlbu54e	207	14	equate	equate	VB
cord-350019-4nlbu54e	207	15	to	to	TO
cord-350019-4nlbu54e	207	16	translation	translation	VB
cord-350019-4nlbu54e	207	17	[	[	-LRB-
cord-350019-4nlbu54e	207	18	147	147	CD
cord-350019-4nlbu54e	207	19	]	]	-RRB-
cord-350019-4nlbu54e	207	20	.	.	.
cord-350019-4nlbu54e	208	1	Furthermore	furthermore	RB
cord-350019-4nlbu54e	208	2	,	,	,
cord-350019-4nlbu54e	208	3	Guttman	Guttman	NNP
cord-350019-4nlbu54e	208	4	et	et	NNP
cord-350019-4nlbu54e	208	5	al	al	NNP
cord-350019-4nlbu54e	208	6	.	.	NNP
cord-350019-4nlbu54e	208	7	concluded	conclude	VBD
cord-350019-4nlbu54e	208	8	that	that	IN
cord-350019-4nlbu54e	208	9	most	most	RBS
cord-350019-4nlbu54e	208	10	noncoding	noncoding	JJ
cord-350019-4nlbu54e	208	11	transcripts	transcript	NNS
cord-350019-4nlbu54e	208	12	are	be	VBP
cord-350019-4nlbu54e	208	13	not	not	RB
cord-350019-4nlbu54e	208	14	translated	translate	VBN
cord-350019-4nlbu54e	208	15	into	into	IN
cord-350019-4nlbu54e	208	16	peptides	peptide	NNS
cord-350019-4nlbu54e	208	17	.	.	.
cord-350019-4nlbu54e	209	1	Several	several	JJ
cord-350019-4nlbu54e	209	2	additional	additional	JJ
cord-350019-4nlbu54e	209	3	studies	study	NNS
cord-350019-4nlbu54e	209	4	have	have	VBP
cord-350019-4nlbu54e	209	5	examined	examine	VBN
cord-350019-4nlbu54e	209	6	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	209	7	binding	bind	VBG
cord-350019-4nlbu54e	209	8	to	to	IN
cord-350019-4nlbu54e	209	9	ribosomes	ribosome	NNS
cord-350019-4nlbu54e	209	10	and	and	CC
cord-350019-4nlbu54e	209	11	have	have	VBP
cord-350019-4nlbu54e	209	12	concluded	conclude	VBN
cord-350019-4nlbu54e	209	13	that	that	IN
cord-350019-4nlbu54e	209	14	ribosome	ribosome	NN
cord-350019-4nlbu54e	209	15	binding	binding	NN
cord-350019-4nlbu54e	209	16	may	may	MD
cord-350019-4nlbu54e	209	17	not	not	RB
cord-350019-4nlbu54e	209	18	be	be	VB
cord-350019-4nlbu54e	209	19	functional	functional	JJ
cord-350019-4nlbu54e	209	20	and	and	CC
cord-350019-4nlbu54e	209	21	may	may	MD
cord-350019-4nlbu54e	209	22	serve	serve	VB
cord-350019-4nlbu54e	209	23	as	as	IN
cord-350019-4nlbu54e	209	24	a	a	DT
cord-350019-4nlbu54e	209	25	quality	quality	NN
cord-350019-4nlbu54e	209	26	control	control	NN
cord-350019-4nlbu54e	209	27	process	process	NN
cord-350019-4nlbu54e	209	28	to	to	TO
cord-350019-4nlbu54e	209	29	degrade	degrade	VB
cord-350019-4nlbu54e	209	30	transcripts	transcript	NNS
cord-350019-4nlbu54e	209	31	with	with	IN
cord-350019-4nlbu54e	209	32	low	low	JJ
cord-350019-4nlbu54e	209	33	coding	coding	NN
cord-350019-4nlbu54e	209	34	potential	potential	NN
cord-350019-4nlbu54e	209	35	via	via	IN
cord-350019-4nlbu54e	209	36	the	the	DT
cord-350019-4nlbu54e	209	37	nonsense	nonsense	NN
cord-350019-4nlbu54e	209	38	-	-	HYPH
cord-350019-4nlbu54e	209	39	mediated	mediate	VBN
cord-350019-4nlbu54e	209	40	decay	decay	NN
cord-350019-4nlbu54e	209	41	(	(	-LRB-
cord-350019-4nlbu54e	209	42	NMD	NMD	NNP
cord-350019-4nlbu54e	209	43	)	)	-RRB-
cord-350019-4nlbu54e	209	44	pathway	pathway	NN
cord-350019-4nlbu54e	209	45	[	[	-LRB-
cord-350019-4nlbu54e	209	46	148	148	CD
cord-350019-4nlbu54e	209	47	,	,	,
cord-350019-4nlbu54e	209	48	149	149	CD
cord-350019-4nlbu54e	209	49	]	]	-RRB-
cord-350019-4nlbu54e	209	50	.	.	.
cord-350019-4nlbu54e	210	1	A	a	DT
cord-350019-4nlbu54e	210	2	recent	recent	JJ
cord-350019-4nlbu54e	210	3	study	study	NN
cord-350019-4nlbu54e	210	4	by	by	IN
cord-350019-4nlbu54e	210	5	Jackson	Jackson	NNP
cord-350019-4nlbu54e	210	6	et	et	NNP
cord-350019-4nlbu54e	210	7	al	al	NNP
cord-350019-4nlbu54e	210	8	.	.	.
cord-350019-4nlbu54e	211	1	used	use	VBN
cord-350019-4nlbu54e	211	2	ribo	ribo	NN
cord-350019-4nlbu54e	211	3	-	-	HYPH
cord-350019-4nlbu54e	211	4	tagging	tagging	NN
cord-350019-4nlbu54e	211	5	in	in	IN
cord-350019-4nlbu54e	211	6	LPS	LPS	NNP
cord-350019-4nlbu54e	211	7	-	-	HYPH
cord-350019-4nlbu54e	211	8	stimulated	stimulate	VBN
cord-350019-4nlbu54e	211	9	mouse	mouse	NN
cord-350019-4nlbu54e	211	10	macrophages	macrophage	NNS
cord-350019-4nlbu54e	211	11	to	to	TO
cord-350019-4nlbu54e	211	12	identify	identify	VB
cord-350019-4nlbu54e	211	13	ribosome	ribosome	NN
cord-350019-4nlbu54e	211	14	footprints	footprint	NNS
cord-350019-4nlbu54e	211	15	within	within	IN
cord-350019-4nlbu54e	211	16	hundreds	hundred	NNS
cord-350019-4nlbu54e	211	17	of	of	IN
cord-350019-4nlbu54e	211	18	annotated	annotate	VBN
cord-350019-4nlbu54e	211	19	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	211	20	,	,	,
cord-350019-4nlbu54e	211	21	raising	raise	VBG
cord-350019-4nlbu54e	211	22	the	the	DT
cord-350019-4nlbu54e	211	23	possibility	possibility	NN
cord-350019-4nlbu54e	211	24	that	that	IN
cord-350019-4nlbu54e	211	25	they	-PRON-	PRP
cord-350019-4nlbu54e	211	26	may	may	MD
cord-350019-4nlbu54e	211	27	be	be	VB
cord-350019-4nlbu54e	211	28	producing	produce	VBG
cord-350019-4nlbu54e	211	29	functional	functional	JJ
cord-350019-4nlbu54e	211	30	peptides	peptide	NNS
cord-350019-4nlbu54e	211	31	[	[	-LRB-
cord-350019-4nlbu54e	211	32	150	150	CD
cord-350019-4nlbu54e	211	33	]	]	-RRB-
cord-350019-4nlbu54e	211	34	.	.	.
cord-350019-4nlbu54e	212	1	They	-PRON-	PRP
cord-350019-4nlbu54e	212	2	characterized	characterize	VBD
cord-350019-4nlbu54e	212	3	an	an	DT
cord-350019-4nlbu54e	212	4	83aa	83aa	JJ
cord-350019-4nlbu54e	212	5	peptide	peptide	NN
cord-350019-4nlbu54e	212	6	located	locate	VBN
cord-350019-4nlbu54e	212	7	within	within	IN
cord-350019-4nlbu54e	212	8	a	a	DT
cord-350019-4nlbu54e	212	9	previously	previously	RB
cord-350019-4nlbu54e	212	10	annotated	annotate	VBN
cord-350019-4nlbu54e	212	11	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	212	12	Aw112010	Aw112010	NNP
cord-350019-4nlbu54e	212	13	and	and	CC
cord-350019-4nlbu54e	212	14	showed	show	VBD
cord-350019-4nlbu54e	212	15	it	-PRON-	PRP
cord-350019-4nlbu54e	212	16	was	be	VBD
cord-350019-4nlbu54e	212	17	produced	produce	VBN
cord-350019-4nlbu54e	212	18	by	by	IN
cord-350019-4nlbu54e	212	19	non	non	JJ
cord-350019-4nlbu54e	212	20	-	-	JJ
cord-350019-4nlbu54e	212	21	canonical	canonical	JJ
cord-350019-4nlbu54e	212	22	"	"	``
cord-350019-4nlbu54e	212	23	CTG	CTG	NNP
cord-350019-4nlbu54e	212	24	"	"	''
cord-350019-4nlbu54e	212	25	translation	translation	NN
cord-350019-4nlbu54e	212	26	initiation	initiation	NN
cord-350019-4nlbu54e	212	27	[	[	-LRB-
cord-350019-4nlbu54e	212	28	150	150	CD
cord-350019-4nlbu54e	212	29	]	]	-RRB-
cord-350019-4nlbu54e	212	30	.	.	.
cord-350019-4nlbu54e	213	1	They	-PRON-	PRP
cord-350019-4nlbu54e	213	2	demonstrated	demonstrate	VBD
cord-350019-4nlbu54e	213	3	that	that	IN
cord-350019-4nlbu54e	213	4	this	this	DT
cord-350019-4nlbu54e	213	5	small	small	JJ
cord-350019-4nlbu54e	213	6	peptide	peptide	NN
cord-350019-4nlbu54e	213	7	had	have	VBD
cord-350019-4nlbu54e	213	8	a	a	DT
cord-350019-4nlbu54e	213	9	critical	critical	JJ
cord-350019-4nlbu54e	213	10	role	role	NN
cord-350019-4nlbu54e	213	11	in	in	IN
cord-350019-4nlbu54e	213	12	mucosal	mucosal	JJ
cord-350019-4nlbu54e	213	13	immunity	immunity	NN
cord-350019-4nlbu54e	213	14	in	in	IN
cord-350019-4nlbu54e	213	15	mice	mouse	NNS
cord-350019-4nlbu54e	213	16	and	and	CC
cord-350019-4nlbu54e	213	17	was	be	VBD
cord-350019-4nlbu54e	213	18	specifically	specifically	RB
cord-350019-4nlbu54e	213	19	required	require	VBN
cord-350019-4nlbu54e	213	20	for	for	IN
cord-350019-4nlbu54e	213	21	the	the	DT
cord-350019-4nlbu54e	213	22	expression	expression	NN
cord-350019-4nlbu54e	213	23	of	of	IN
cord-350019-4nlbu54e	213	24	Il12	Il12	NNP
cord-350019-4nlbu54e	214	1	mRNA	mRNA	NNP
cord-350019-4nlbu54e	214	2	[	[	-LRB-
cord-350019-4nlbu54e	214	3	150	150	CD
cord-350019-4nlbu54e	214	4	]	]	-RRB-
cord-350019-4nlbu54e	214	5	.	.	.
cord-350019-4nlbu54e	215	1	The	the	DT
cord-350019-4nlbu54e	215	2	exact	exact	JJ
cord-350019-4nlbu54e	215	3	mechanism	mechanism	NN
cord-350019-4nlbu54e	215	4	of	of	IN
cord-350019-4nlbu54e	215	5	how	how	WRB
cord-350019-4nlbu54e	215	6	this	this	DT
cord-350019-4nlbu54e	215	7	peptide	peptide	NN
cord-350019-4nlbu54e	215	8	drives	drive	VBZ
cord-350019-4nlbu54e	215	9	Il12	Il12	.
cord-350019-4nlbu54e	216	1	expression	expression	NN
cord-350019-4nlbu54e	216	2	is	be	VBZ
cord-350019-4nlbu54e	216	3	yet	yet	RB
cord-350019-4nlbu54e	216	4	to	to	TO
cord-350019-4nlbu54e	216	5	be	be	VB
cord-350019-4nlbu54e	216	6	elucidated	elucidate	VBN
cord-350019-4nlbu54e	216	7	.	.	.
cord-350019-4nlbu54e	217	1	The	the	DT
cord-350019-4nlbu54e	217	2	laborious	laborious	JJ
cord-350019-4nlbu54e	217	3	process	process	NN
cord-350019-4nlbu54e	217	4	of	of	IN
cord-350019-4nlbu54e	217	5	functionally	functionally	RB
cord-350019-4nlbu54e	217	6	characterizing	characterize	VBG
cord-350019-4nlbu54e	217	7	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	217	8	has	have	VBZ
cord-350019-4nlbu54e	217	9	remained	remain	VBN
cord-350019-4nlbu54e	217	10	a	a	DT
cord-350019-4nlbu54e	217	11	major	major	JJ
cord-350019-4nlbu54e	217	12	limitation	limitation	NN
cord-350019-4nlbu54e	217	13	to	to	TO
cord-350019-4nlbu54e	217	14	lncRNA	lncrna	VB
cord-350019-4nlbu54e	217	15	functional	functional	JJ
cord-350019-4nlbu54e	217	16	discovery	discovery	NN
cord-350019-4nlbu54e	217	17	.	.	.
cord-350019-4nlbu54e	218	1	For	for	IN
cord-350019-4nlbu54e	218	2	example	example	NN
cord-350019-4nlbu54e	218	3	,	,	,
cord-350019-4nlbu54e	218	4	while~16,000	while~16,000	NNP
cord-350019-4nlbu54e	218	5	long	long	JJ
cord-350019-4nlbu54e	218	6	noncoding	noncoding	JJ
cord-350019-4nlbu54e	218	7	RNAs	rna	NNS
cord-350019-4nlbu54e	218	8	(	(	-LRB-
cord-350019-4nlbu54e	218	9	lncRNAs	lncrnas	RB
cord-350019-4nlbu54e	218	10	)	)	-RRB-
cord-350019-4nlbu54e	218	11	have	have	VBP
cord-350019-4nlbu54e	218	12	been	be	VBN
cord-350019-4nlbu54e	218	13	identified	identify	VBN
cord-350019-4nlbu54e	218	14	in	in	IN
cord-350019-4nlbu54e	218	15	the	the	DT
cord-350019-4nlbu54e	218	16	human	human	JJ
cord-350019-4nlbu54e	218	17	genome	genome	NN
cord-350019-4nlbu54e	218	18	,	,	,
cord-350019-4nlbu54e	218	19	only	only	RB
cord-350019-4nlbu54e	218	20	3	3	CD
cord-350019-4nlbu54e	218	21	%	%	NN
cord-350019-4nlbu54e	218	22	of	of	IN
cord-350019-4nlbu54e	218	23	all	all	DT
cord-350019-4nlbu54e	218	24	validated	validate	VBN
cord-350019-4nlbu54e	218	25	lncRNAs	lncRNAs	NNPS
cord-350019-4nlbu54e	218	26	have	have	VB
cord-350019-4nlbu54e	218	27	an	an	DT
cord-350019-4nlbu54e	218	28	ascribed	ascribe	VBN
cord-350019-4nlbu54e	218	29	function	function	NN
cord-350019-4nlbu54e	218	30	[	[	-LRB-
cord-350019-4nlbu54e	218	31	47	47	CD
cord-350019-4nlbu54e	218	32	,	,	,
cord-350019-4nlbu54e	218	33	91	91	CD
cord-350019-4nlbu54e	218	34	,	,	,
cord-350019-4nlbu54e	218	35	151	151	CD
cord-350019-4nlbu54e	218	36	]	]	-RRB-
cord-350019-4nlbu54e	218	37	.	.	.
cord-350019-4nlbu54e	219	1	For	for	IN
cord-350019-4nlbu54e	219	2	more	more	JJR
cord-350019-4nlbu54e	219	3	than	than	IN
cord-350019-4nlbu54e	219	4	two	two	CD
cord-350019-4nlbu54e	219	5	decades	decade	NNS
cord-350019-4nlbu54e	219	6	since	since	IN
cord-350019-4nlbu54e	219	7	its	-PRON-	PRP$
cord-350019-4nlbu54e	219	8	discovery	discovery	NN
cord-350019-4nlbu54e	219	9	,	,	,
cord-350019-4nlbu54e	219	10	RNA	RNA	NNP
cord-350019-4nlbu54e	219	11	interference	interference	NN
cord-350019-4nlbu54e	219	12	(	(	-LRB-
cord-350019-4nlbu54e	219	13	RNAi	RNAi	NNP
cord-350019-4nlbu54e	219	14	)	)	-RRB-
cord-350019-4nlbu54e	219	15	has	have	VBZ
cord-350019-4nlbu54e	219	16	been	be	VBN
cord-350019-4nlbu54e	219	17	the	the	DT
cord-350019-4nlbu54e	219	18	method	method	NN
cord-350019-4nlbu54e	219	19	of	of	IN
cord-350019-4nlbu54e	219	20	choice	choice	NN
cord-350019-4nlbu54e	219	21	for	for	IN
cord-350019-4nlbu54e	219	22	loss	loss	NN
cord-350019-4nlbu54e	219	23	of	of	IN
cord-350019-4nlbu54e	219	24	function	function	NN
cord-350019-4nlbu54e	219	25	studies	study	NNS
cord-350019-4nlbu54e	219	26	.	.	.
cord-350019-4nlbu54e	220	1	The	the	DT
cord-350019-4nlbu54e	220	2	ease	ease	NN
cord-350019-4nlbu54e	220	3	and	and	CC
cord-350019-4nlbu54e	220	4	versatility	versatility	NN
cord-350019-4nlbu54e	220	5	of	of	IN
cord-350019-4nlbu54e	220	6	RNAi	RNAi	NNS
cord-350019-4nlbu54e	220	7	make	make	VBP
cord-350019-4nlbu54e	220	8	it	-PRON-	PRP
cord-350019-4nlbu54e	220	9	appealing	appealing	JJ
cord-350019-4nlbu54e	220	10	for	for	IN
cord-350019-4nlbu54e	220	11	use	use	NN
cord-350019-4nlbu54e	220	12	,	,	,
cord-350019-4nlbu54e	220	13	requiring	require	VBG
cord-350019-4nlbu54e	220	14	short	short	JJ
cord-350019-4nlbu54e	220	15	complementary	complementary	JJ
cord-350019-4nlbu54e	220	16	small	small	JJ
cord-350019-4nlbu54e	220	17	RNAs	rna	NNS
cord-350019-4nlbu54e	220	18	transfected	transfecte	VBN
cord-350019-4nlbu54e	220	19	into	into	IN
cord-350019-4nlbu54e	220	20	cells	cell	NNS
cord-350019-4nlbu54e	220	21	that	that	WDT
cord-350019-4nlbu54e	220	22	can	can	MD
cord-350019-4nlbu54e	220	23	then	then	RB
cord-350019-4nlbu54e	220	24	utilize	utilize	VB
cord-350019-4nlbu54e	220	25	the	the	DT
cord-350019-4nlbu54e	220	26	endogenous	endogenous	JJ
cord-350019-4nlbu54e	220	27	cellular	cellular	JJ
cord-350019-4nlbu54e	220	28	machinery	machinery	NN
cord-350019-4nlbu54e	220	29	to	to	TO
cord-350019-4nlbu54e	220	30	target	target	VB
cord-350019-4nlbu54e	220	31	specific	specific	JJ
cord-350019-4nlbu54e	220	32	transcripts	transcript	NNS
cord-350019-4nlbu54e	220	33	[	[	-LRB-
cord-350019-4nlbu54e	220	34	152	152	CD
cord-350019-4nlbu54e	220	35	,	,	,
cord-350019-4nlbu54e	220	36	153	153	CD
cord-350019-4nlbu54e	220	37	]	]	-RRB-
cord-350019-4nlbu54e	221	1	(	(	-LRB-
cord-350019-4nlbu54e	221	2	Fig	Fig	NNP
cord-350019-4nlbu54e	221	3	.	.	.
cord-350019-4nlbu54e	221	4	3A	3A	NNP
cord-350019-4nlbu54e	221	5	)	)	-RRB-
cord-350019-4nlbu54e	221	6	.	.	.
cord-350019-4nlbu54e	222	1	Additionally	additionally	RB
cord-350019-4nlbu54e	222	2	,	,	,
cord-350019-4nlbu54e	222	3	short	short	JJ
cord-350019-4nlbu54e	222	4	hairpin	hairpin	NN
cord-350019-4nlbu54e	222	5	RNAs	rna	NNS
cord-350019-4nlbu54e	222	6	(	(	-LRB-
cord-350019-4nlbu54e	222	7	shRNAs	shRNAs	NNP
cord-350019-4nlbu54e	222	8	)	)	-RRB-
cord-350019-4nlbu54e	222	9	can	can	MD
cord-350019-4nlbu54e	222	10	be	be	VB
cord-350019-4nlbu54e	222	11	expressed	express	VBN
cord-350019-4nlbu54e	222	12	in	in	IN
cord-350019-4nlbu54e	222	13	a	a	DT
cord-350019-4nlbu54e	222	14	lentiviral	lentiviral	JJ
cord-350019-4nlbu54e	222	15	context	context	NN
cord-350019-4nlbu54e	222	16	to	to	TO
cord-350019-4nlbu54e	222	17	accomplish	accomplish	VB
cord-350019-4nlbu54e	222	18	stable	stable	JJ
cord-350019-4nlbu54e	222	19	RNAi	RNAi	NNS
cord-350019-4nlbu54e	222	20	in	in	IN
cord-350019-4nlbu54e	222	21	cells	cell	NNS
cord-350019-4nlbu54e	222	22	[	[	-LRB-
cord-350019-4nlbu54e	222	23	154	154	CD
cord-350019-4nlbu54e	222	24	]	]	-RRB-
cord-350019-4nlbu54e	222	25	.	.	.
cord-350019-4nlbu54e	223	1	RNAi	RNAi	NNP
cord-350019-4nlbu54e	223	2	is	be	VBZ
cord-350019-4nlbu54e	223	3	most	most	RBS
cord-350019-4nlbu54e	223	4	active	active	JJ
cord-350019-4nlbu54e	223	5	in	in	IN
cord-350019-4nlbu54e	223	6	the	the	DT
cord-350019-4nlbu54e	223	7	cytoplasm	cytoplasm	NN
cord-350019-4nlbu54e	223	8	,	,	,
cord-350019-4nlbu54e	223	9	which	which	WDT
cord-350019-4nlbu54e	223	10	makes	make	VBZ
cord-350019-4nlbu54e	223	11	it	-PRON-	PRP
cord-350019-4nlbu54e	223	12	most	most	RBS
cord-350019-4nlbu54e	223	13	useful	useful	JJ
cord-350019-4nlbu54e	223	14	for	for	IN
cord-350019-4nlbu54e	223	15	targeting	target	VBG
cord-350019-4nlbu54e	223	16	mRNAs	mrnas	CD
cord-350019-4nlbu54e	223	17	and	and	CC
cord-350019-4nlbu54e	223	18	lncRNAs	lncrnas	VB
cord-350019-4nlbu54e	223	19	that	that	WDT
cord-350019-4nlbu54e	223	20	reside	reside	VBP
cord-350019-4nlbu54e	223	21	in	in	IN
cord-350019-4nlbu54e	223	22	the	the	DT
cord-350019-4nlbu54e	223	23	cytoplasm	cytoplasm	NN
cord-350019-4nlbu54e	223	24	[	[	-LRB-
cord-350019-4nlbu54e	223	25	155	155	CD
cord-350019-4nlbu54e	223	26	]	]	-RRB-
cord-350019-4nlbu54e	223	27	.	.	.
cord-350019-4nlbu54e	224	1	Success	success	NN
cord-350019-4nlbu54e	224	2	in	in	IN
cord-350019-4nlbu54e	224	3	knocking	knock	VBG
cord-350019-4nlbu54e	224	4	down	down	RP
cord-350019-4nlbu54e	224	5	some	some	DT
cord-350019-4nlbu54e	224	6	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	224	7	,	,	,
cord-350019-4nlbu54e	224	8	for	for	IN
cord-350019-4nlbu54e	224	9	example	example	NN
cord-350019-4nlbu54e	225	1	lincRNA	lincRNA	NNP
cord-350019-4nlbu54e	225	2	-	-	:
cord-350019-4nlbu54e	225	3	Cox2	Cox2	NNP
cord-350019-4nlbu54e	225	4	,	,	,
cord-350019-4nlbu54e	225	5	has	have	VBZ
cord-350019-4nlbu54e	225	6	been	be	VBN
cord-350019-4nlbu54e	225	7	attributed	attribute	VBN
cord-350019-4nlbu54e	225	8	to	to	IN
cord-350019-4nlbu54e	225	9	the	the	DT
cord-350019-4nlbu54e	225	10	fact	fact	NN
cord-350019-4nlbu54e	225	11	that	that	IN
cord-350019-4nlbu54e	225	12	this	this	DT
cord-350019-4nlbu54e	225	13	lncRNA	lncrna	NN
cord-350019-4nlbu54e	225	14	is	be	VBZ
cord-350019-4nlbu54e	225	15	expressed	express	VBN
cord-350019-4nlbu54e	225	16	both	both	CC
cord-350019-4nlbu54e	225	17	in	in	IN
cord-350019-4nlbu54e	225	18	the	the	DT
cord-350019-4nlbu54e	225	19	cytoplasm	cytoplasm	NN
cord-350019-4nlbu54e	225	20	and	and	CC
cord-350019-4nlbu54e	225	21	the	the	DT
cord-350019-4nlbu54e	225	22	nucleus	nucleus	NN
cord-350019-4nlbu54e	225	23	(	(	-LRB-
cord-350019-4nlbu54e	225	24	perhaps	perhaps	RB
cord-350019-4nlbu54e	225	25	cycling	cycle	VBG
cord-350019-4nlbu54e	225	26	between	between	IN
cord-350019-4nlbu54e	225	27	both	both	DT
cord-350019-4nlbu54e	225	28	compartments	compartment	NNS
cord-350019-4nlbu54e	225	29	)	)	-RRB-
cord-350019-4nlbu54e	225	30	and	and	CC
cord-350019-4nlbu54e	225	31	hence	hence	RB
cord-350019-4nlbu54e	225	32	is	be	VBZ
cord-350019-4nlbu54e	225	33	susceptible	susceptible	JJ
cord-350019-4nlbu54e	225	34	to	to	IN
cord-350019-4nlbu54e	225	35	RNAi	RNAi	NNS
cord-350019-4nlbu54e	225	36	[	[	-LRB-
cord-350019-4nlbu54e	225	37	42	42	CD
cord-350019-4nlbu54e	225	38	]	]	-RRB-
cord-350019-4nlbu54e	225	39	.	.	.
cord-350019-4nlbu54e	226	1	However	however	RB
cord-350019-4nlbu54e	226	2	,	,	,
cord-350019-4nlbu54e	226	3	many	many	JJ
cord-350019-4nlbu54e	226	4	lncRNAs	lncrna	NNS
cord-350019-4nlbu54e	226	5	are	be	VBP
cord-350019-4nlbu54e	226	6	thought	think	VBN
cord-350019-4nlbu54e	226	7	to	to	TO
cord-350019-4nlbu54e	226	8	be	be	VB
cord-350019-4nlbu54e	226	9	nuclear	nuclear	JJ
cord-350019-4nlbu54e	226	10	-	-	HYPH
cord-350019-4nlbu54e	226	11	restricted	restrict	VBN
cord-350019-4nlbu54e	226	12	where	where	WRB
cord-350019-4nlbu54e	226	13	RNAi	RNAi	NNP
cord-350019-4nlbu54e	226	14	has	have	VBZ
cord-350019-4nlbu54e	226	15	been	be	VBN
cord-350019-4nlbu54e	226	16	demonstrated	demonstrate	VBN
cord-350019-4nlbu54e	226	17	to	to	TO
cord-350019-4nlbu54e	226	18	have	have	VB
cord-350019-4nlbu54e	226	19	limited	limit	VBN
cord-350019-4nlbu54e	226	20	efficiency	efficiency	NN
cord-350019-4nlbu54e	226	21	[	[	-LRB-
cord-350019-4nlbu54e	226	22	156	156	CD
cord-350019-4nlbu54e	226	23	]	]	-RRB-
cord-350019-4nlbu54e	227	1	(	(	-LRB-
cord-350019-4nlbu54e	227	2	Fig	Fig	NNP
cord-350019-4nlbu54e	227	3	.	.	.
cord-350019-4nlbu54e	227	4	3	3	CD
cord-350019-4nlbu54e	227	5	)	)	-RRB-
cord-350019-4nlbu54e	227	6	.	.	.
cord-350019-4nlbu54e	228	1	Antisense	Antisense	NNP
cord-350019-4nlbu54e	228	2	oligonucleotides	oligonucleotide	NNS
cord-350019-4nlbu54e	228	3	(	(	-LRB-
cord-350019-4nlbu54e	228	4	ASOs	ASOs	NNP
cord-350019-4nlbu54e	228	5	)	)	-RRB-
cord-350019-4nlbu54e	228	6	can	can	MD
cord-350019-4nlbu54e	228	7	be	be	VB
cord-350019-4nlbu54e	228	8	either	either	CC
cord-350019-4nlbu54e	228	9	RNA	RNA	NNP
cord-350019-4nlbu54e	228	10	or	or	CC
cord-350019-4nlbu54e	228	11	DNA	dna	NN
cord-350019-4nlbu54e	228	12	-	-	HYPH
cord-350019-4nlbu54e	228	13	based	base	VBN
cord-350019-4nlbu54e	228	14	and	and	CC
cord-350019-4nlbu54e	228	15	can	can	MD
cord-350019-4nlbu54e	228	16	be	be	VB
cord-350019-4nlbu54e	228	17	used	use	VBN
cord-350019-4nlbu54e	228	18	to	to	TO
cord-350019-4nlbu54e	228	19	target	target	VB
cord-350019-4nlbu54e	228	20	complementary	complementary	JJ
cord-350019-4nlbu54e	228	21	sequences	sequence	NNS
cord-350019-4nlbu54e	228	22	within	within	IN
cord-350019-4nlbu54e	228	23	a	a	DT
cord-350019-4nlbu54e	228	24	transcript	transcript	NN
cord-350019-4nlbu54e	228	25	.	.	.
cord-350019-4nlbu54e	229	1	Unlike	unlike	IN
cord-350019-4nlbu54e	229	2	RNAi	RNAi	NNP
cord-350019-4nlbu54e	229	3	,	,	,
cord-350019-4nlbu54e	229	4	ASOs	ASOs	NNP
cord-350019-4nlbu54e	229	5	do	do	VBP
cord-350019-4nlbu54e	229	6	not	not	RB
cord-350019-4nlbu54e	229	7	engage	engage	VB
cord-350019-4nlbu54e	229	8	the	the	DT
cord-350019-4nlbu54e	229	9	cellular	cellular	JJ
cord-350019-4nlbu54e	229	10	RNAi	RNAi	NNP
cord-350019-4nlbu54e	229	11	machinery	machinery	NN
cord-350019-4nlbu54e	229	12	[	[	-LRB-
cord-350019-4nlbu54e	229	13	157	157	CD
cord-350019-4nlbu54e	229	14	]	]	-RRB-
cord-350019-4nlbu54e	229	15	.	.	.
cord-350019-4nlbu54e	230	1	Instead	instead	RB
cord-350019-4nlbu54e	230	2	,	,	,
cord-350019-4nlbu54e	230	3	ASOs	ASOs	NNP
cord-350019-4nlbu54e	230	4	function	function	NN
cord-350019-4nlbu54e	230	5	by	by	IN
cord-350019-4nlbu54e	230	6	hybridizing	hybridize	VBG
cord-350019-4nlbu54e	230	7	to	to	IN
cord-350019-4nlbu54e	230	8	the	the	DT
cord-350019-4nlbu54e	230	9	target	target	NN
cord-350019-4nlbu54e	230	10	RNA	RNA	NNP
cord-350019-4nlbu54e	230	11	and	and	CC
cord-350019-4nlbu54e	230	12	inhibiting	inhibit	VBG
cord-350019-4nlbu54e	230	13	its	-PRON-	PRP$
cord-350019-4nlbu54e	230	14	function	function	NN
cord-350019-4nlbu54e	230	15	by	by	IN
cord-350019-4nlbu54e	230	16	either	either	CC
cord-350019-4nlbu54e	230	17	inducing	induce	VBG
cord-350019-4nlbu54e	230	18	the	the	DT
cord-350019-4nlbu54e	230	19	RNase	RNase	NNP
cord-350019-4nlbu54e	230	20	H	h	NN
cord-350019-4nlbu54e	230	21	pathway	pathway	NN
cord-350019-4nlbu54e	230	22	or	or	CC
cord-350019-4nlbu54e	230	23	by	by	IN
cord-350019-4nlbu54e	230	24	steric	steric	JJ
cord-350019-4nlbu54e	230	25	inhibition	inhibition	NN
cord-350019-4nlbu54e	230	26	.	.	.
cord-350019-4nlbu54e	231	1	The	the	DT
cord-350019-4nlbu54e	231	2	RNase	rnase	NN
cord-350019-4nlbu54e	231	3	H	h	NN
cord-350019-4nlbu54e	231	4	enzyme	enzyme	NN
cord-350019-4nlbu54e	231	5	is	be	VBZ
cord-350019-4nlbu54e	231	6	part	part	NN
cord-350019-4nlbu54e	231	7	of	of	IN
cord-350019-4nlbu54e	231	8	a	a	DT
cord-350019-4nlbu54e	231	9	cellular	cellular	JJ
cord-350019-4nlbu54e	231	10	pathway	pathway	NN
cord-350019-4nlbu54e	231	11	that	that	WDT
cord-350019-4nlbu54e	231	12	normally	normally	RB
cord-350019-4nlbu54e	231	13	functions	function	VBZ
cord-350019-4nlbu54e	231	14	to	to	TO
cord-350019-4nlbu54e	231	15	resolve	resolve	VB
cord-350019-4nlbu54e	231	16	unwanted	unwanted	JJ
cord-350019-4nlbu54e	231	17	DNA	dna	NN
cord-350019-4nlbu54e	231	18	:	:	:
cord-350019-4nlbu54e	231	19	RNA	rna	NN
cord-350019-4nlbu54e	231	20	interactions	interaction	NNS
cord-350019-4nlbu54e	231	21	that	that	WDT
cord-350019-4nlbu54e	231	22	can	can	MD
cord-350019-4nlbu54e	231	23	occur	occur	VB
cord-350019-4nlbu54e	231	24	during	during	IN
cord-350019-4nlbu54e	231	25	replication	replication	NN
cord-350019-4nlbu54e	231	26	and/or	and/or	CC
cord-350019-4nlbu54e	231	27	transcription	transcription	NN
cord-350019-4nlbu54e	231	28	[	[	-LRB-
cord-350019-4nlbu54e	231	29	158	158	CD
cord-350019-4nlbu54e	231	30	]	]	-RRB-
cord-350019-4nlbu54e	231	31	.	.	.
cord-350019-4nlbu54e	232	1	One	one	CD
cord-350019-4nlbu54e	232	2	of	of	IN
cord-350019-4nlbu54e	232	3	the	the	DT
cord-350019-4nlbu54e	232	4	most	most	RBS
cord-350019-4nlbu54e	232	5	widely	widely	RB
cord-350019-4nlbu54e	232	6	used	use	VBN
cord-350019-4nlbu54e	232	7	types	type	NNS
cord-350019-4nlbu54e	232	8	of	of	IN
cord-350019-4nlbu54e	232	9	ASOs	ASOs	NNP
cord-350019-4nlbu54e	232	10	for	for	IN
cord-350019-4nlbu54e	232	11	targeting	target	VBG
cord-350019-4nlbu54e	232	12	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	232	13	are	be	VBP
cord-350019-4nlbu54e	232	14	gapmers	gapmer	NNS
cord-350019-4nlbu54e	232	15	which	which	WDT
cord-350019-4nlbu54e	232	16	contain	contain	VBP
cord-350019-4nlbu54e	232	17	a	a	DT
cord-350019-4nlbu54e	232	18	"	"	``
cord-350019-4nlbu54e	232	19	hybrid	hybrid	NN
cord-350019-4nlbu54e	232	20	"	"	''
cord-350019-4nlbu54e	232	21	modified	modify	VBN
cord-350019-4nlbu54e	232	22	/	/	SYM
cord-350019-4nlbu54e	232	23	unmodified	unmodified	JJ
cord-350019-4nlbu54e	232	24	configuration	configuration	NN
cord-350019-4nlbu54e	232	25	consisting	consist	VBG
cord-350019-4nlbu54e	232	26	of	of	IN
cord-350019-4nlbu54e	232	27	10	10	CD
cord-350019-4nlbu54e	232	28	nt	nt	RB
cord-350019-4nlbu54e	232	29	DNA	dna	NN
cord-350019-4nlbu54e	232	30	core	core	NN
cord-350019-4nlbu54e	232	31	flanked	flank	VBN
cord-350019-4nlbu54e	232	32	by	by	IN
cord-350019-4nlbu54e	232	33	2′-O	2′-o	CD
cord-350019-4nlbu54e	232	34	-	-	:
cord-350019-4nlbu54e	232	35	Methyl	Methyl	NNP
cord-350019-4nlbu54e	232	36	or	or	CC
cord-350019-4nlbu54e	232	37	LNA	LNA	NNP
cord-350019-4nlbu54e	232	38	-	-	HYPH
cord-350019-4nlbu54e	232	39	modified	modify	VBN
cord-350019-4nlbu54e	232	40	synthetic	synthetic	JJ
cord-350019-4nlbu54e	232	41	nucleotides	nucleotide	NNS
cord-350019-4nlbu54e	232	42	(	(	-LRB-
cord-350019-4nlbu54e	232	43	Fig	fig	NN
cord-350019-4nlbu54e	232	44	.	.	.
cord-350019-4nlbu54e	232	45	3B	3B	NNP
cord-350019-4nlbu54e	232	46	)	)	-RRB-
cord-350019-4nlbu54e	232	47	.	.	.
cord-350019-4nlbu54e	233	1	Gapmers	gapmer	NNS
cord-350019-4nlbu54e	233	2	offer	offer	VBP
cord-350019-4nlbu54e	233	3	the	the	DT
cord-350019-4nlbu54e	233	4	benefit	benefit	NN
cord-350019-4nlbu54e	233	5	of	of	IN
cord-350019-4nlbu54e	233	6	modifications	modification	NNS
cord-350019-4nlbu54e	233	7	for	for	IN
cord-350019-4nlbu54e	233	8	stability	stability	NN
cord-350019-4nlbu54e	233	9	and	and	CC
cord-350019-4nlbu54e	233	10	reduced	reduce	VBN
cord-350019-4nlbu54e	233	11	toxicity	toxicity	NN
cord-350019-4nlbu54e	233	12	,	,	,
cord-350019-4nlbu54e	233	13	while	while	IN
cord-350019-4nlbu54e	233	14	still	still	RB
cord-350019-4nlbu54e	233	15	allowing	allow	VBG
cord-350019-4nlbu54e	233	16	engagement	engagement	NN
cord-350019-4nlbu54e	233	17	of	of	IN
cord-350019-4nlbu54e	233	18	the	the	DT
cord-350019-4nlbu54e	233	19	RNase	RNase	NNP
cord-350019-4nlbu54e	233	20	H	h	NN
cord-350019-4nlbu54e	233	21	pathway	pathway	NN
cord-350019-4nlbu54e	233	22	(	(	-LRB-
cord-350019-4nlbu54e	233	23	Fig	fig	NN
cord-350019-4nlbu54e	233	24	.	.	.
cord-350019-4nlbu54e	233	25	3B	3b	LS
cord-350019-4nlbu54e	233	26	)	)	-RRB-
cord-350019-4nlbu54e	233	27	[	[	-LRB-
cord-350019-4nlbu54e	233	28	159	159	CD
cord-350019-4nlbu54e	233	29	]	]	-RRB-
cord-350019-4nlbu54e	233	30	.	.	.
cord-350019-4nlbu54e	234	1	Efficient	efficient	JJ
cord-350019-4nlbu54e	234	2	depletion	depletion	NN
cord-350019-4nlbu54e	234	3	of	of	IN
cord-350019-4nlbu54e	234	4	nuclear	nuclear	JJ
cord-350019-4nlbu54e	234	5	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	234	6	has	have	VBZ
cord-350019-4nlbu54e	234	7	been	be	VBN
cord-350019-4nlbu54e	234	8	demonstrated	demonstrate	VBN
cord-350019-4nlbu54e	234	9	using	use	VBG
cord-350019-4nlbu54e	234	10	modified	modify	VBN
cord-350019-4nlbu54e	234	11	DNA	DNA	NNP
cord-350019-4nlbu54e	234	12	anti	anti	JJ
cord-350019-4nlbu54e	234	13	-	-	JJ
cord-350019-4nlbu54e	234	14	sense	sense	JJ
cord-350019-4nlbu54e	234	15	oligonucleotides	oligonucleotide	NNS
cord-350019-4nlbu54e	234	16	[	[	-LRB-
cord-350019-4nlbu54e	234	17	155	155	CD
cord-350019-4nlbu54e	234	18	]	]	-RRB-
cord-350019-4nlbu54e	234	19	.	.	.
cord-350019-4nlbu54e	235	1	Ilott	Ilott	NNP
cord-350019-4nlbu54e	235	2	et	et	NNP
cord-350019-4nlbu54e	235	3	al	al	NNP
cord-350019-4nlbu54e	235	4	.	.	.
cord-350019-4nlbu54e	236	1	used	use	VBN
cord-350019-4nlbu54e	236	2	gapmers	gapmer	NNS
cord-350019-4nlbu54e	236	3	to	to	TO
cord-350019-4nlbu54e	236	4	successfully	successfully	RB
cord-350019-4nlbu54e	236	5	knock	knock	VB
cord-350019-4nlbu54e	236	6	-	-	HYPH
cord-350019-4nlbu54e	236	7	down	down	RP
cord-350019-4nlbu54e	236	8	TLR	TLR	NNP
cord-350019-4nlbu54e	236	9	-	-	HYPH
cord-350019-4nlbu54e	236	10	induced	induce	VBN
cord-350019-4nlbu54e	236	11	enhancer	enhancer	NN
cord-350019-4nlbu54e	236	12	RNA	RNA	NNP
cord-350019-4nlbu54e	236	13	,	,	,
cord-350019-4nlbu54e	236	14	as	as	IN
cord-350019-4nlbu54e	236	15	they	-PRON-	PRP
cord-350019-4nlbu54e	236	16	were	be	VBD
cord-350019-4nlbu54e	236	17	unable	unable	JJ
cord-350019-4nlbu54e	236	18	to	to	TO
cord-350019-4nlbu54e	236	19	knock	knock	VB
cord-350019-4nlbu54e	236	20	-	-	HYPH
cord-350019-4nlbu54e	236	21	down	down	RP
cord-350019-4nlbu54e	236	22	these	these	DT
cord-350019-4nlbu54e	236	23	same	same	JJ
cord-350019-4nlbu54e	237	1	eRNAs	erna	VBG
cord-350019-4nlbu54e	237	2	with	with	IN
cord-350019-4nlbu54e	237	3	4	4	CD
cord-350019-4nlbu54e	237	4	different	different	JJ
cord-350019-4nlbu54e	237	5	siRNAs	sirna	NNS
cord-350019-4nlbu54e	237	6	[	[	-LRB-
cord-350019-4nlbu54e	237	7	56	56	CD
cord-350019-4nlbu54e	237	8	]	]	-RRB-
cord-350019-4nlbu54e	237	9	.	.	.
cord-350019-4nlbu54e	238	1	Recent	recent	JJ
cord-350019-4nlbu54e	238	2	in	in	IN
cord-350019-4nlbu54e	238	3	vivo	vivo	NN
cord-350019-4nlbu54e	238	4	applications	application	NNS
cord-350019-4nlbu54e	238	5	for	for	IN
cord-350019-4nlbu54e	238	6	DNA	dna	NN
cord-350019-4nlbu54e	238	7	oligonucleotides	oligonucleotide	NNS
cord-350019-4nlbu54e	238	8	have	have	VBP
cord-350019-4nlbu54e	238	9	also	also	RB
cord-350019-4nlbu54e	238	10	proven	prove	VBN
cord-350019-4nlbu54e	238	11	successful	successful	JJ
cord-350019-4nlbu54e	238	12	as	as	IN
cord-350019-4nlbu54e	238	13	a	a	DT
cord-350019-4nlbu54e	238	14	possible	possible	JJ
cord-350019-4nlbu54e	238	15	treatment	treatment	NN
cord-350019-4nlbu54e	238	16	of	of	IN
cord-350019-4nlbu54e	238	17	a	a	DT
cord-350019-4nlbu54e	238	18	neural	neural	JJ
cord-350019-4nlbu54e	238	19	degenerative	degenerative	JJ
cord-350019-4nlbu54e	238	20	disease	disease	NN
cord-350019-4nlbu54e	238	21	called	call	VBN
cord-350019-4nlbu54e	238	22	Angelman	Angelman	NNP
cord-350019-4nlbu54e	238	23	's	's	POS
cord-350019-4nlbu54e	238	24	syndrome	syndrome	NN
cord-350019-4nlbu54e	238	25	.	.	.
cord-350019-4nlbu54e	239	1	Angelman	Angelman	NNP
cord-350019-4nlbu54e	239	2	's	's	POS
cord-350019-4nlbu54e	239	3	syndrome	syndrome	NN
cord-350019-4nlbu54e	239	4	is	be	VBZ
cord-350019-4nlbu54e	239	5	a	a	DT
cord-350019-4nlbu54e	239	6	monogenic	monogenic	JJ
cord-350019-4nlbu54e	239	7	disorder	disorder	NN
cord-350019-4nlbu54e	239	8	caused	cause	VBN
cord-350019-4nlbu54e	239	9	by	by	IN
cord-350019-4nlbu54e	239	10	mutations	mutation	NNS
cord-350019-4nlbu54e	239	11	in	in	IN
cord-350019-4nlbu54e	239	12	the	the	DT
cord-350019-4nlbu54e	239	13	E3	e3	NN
cord-350019-4nlbu54e	239	14	ubiquitin	ubiquitin	NN
cord-350019-4nlbu54e	239	15	ligase	ligase	NN
cord-350019-4nlbu54e	239	16	3A	3A	NNP
cord-350019-4nlbu54e	239	17	(	(	-LRB-
cord-350019-4nlbu54e	239	18	UBE3A	ube3a	CD
cord-350019-4nlbu54e	239	19	)	)	-RRB-
cord-350019-4nlbu54e	239	20	[	[	-LRB-
cord-350019-4nlbu54e	239	21	160	160	CD
cord-350019-4nlbu54e	239	22	,	,	,
cord-350019-4nlbu54e	239	23	161	161	CD
cord-350019-4nlbu54e	239	24	]	]	-RRB-
cord-350019-4nlbu54e	239	25	.	.	.
cord-350019-4nlbu54e	240	1	As	as	IN
cord-350019-4nlbu54e	240	2	UBE3A	ube3a	CD
cord-350019-4nlbu54e	240	3	is	be	VBZ
cord-350019-4nlbu54e	240	4	a	a	DT
cord-350019-4nlbu54e	240	5	paternally	paternally	RB
cord-350019-4nlbu54e	240	6	-	-	HYPH
cord-350019-4nlbu54e	240	7	imprinted	imprint	VBN
cord-350019-4nlbu54e	240	8	gene	gene	NN
cord-350019-4nlbu54e	240	9	,	,	,
cord-350019-4nlbu54e	240	10	a	a	DT
cord-350019-4nlbu54e	240	11	mutation	mutation	NN
cord-350019-4nlbu54e	240	12	in	in	IN
cord-350019-4nlbu54e	240	13	the	the	DT
cord-350019-4nlbu54e	240	14	maternal	maternal	JJ
cord-350019-4nlbu54e	240	15	allele	allele	NN
cord-350019-4nlbu54e	240	16	is	be	VBZ
cord-350019-4nlbu54e	240	17	sufficient	sufficient	JJ
cord-350019-4nlbu54e	240	18	to	to	TO
cord-350019-4nlbu54e	240	19	lead	lead	VB
cord-350019-4nlbu54e	240	20	to	to	IN
cord-350019-4nlbu54e	240	21	disease	disease	NN
cord-350019-4nlbu54e	240	22	[	[	-LRB-
cord-350019-4nlbu54e	240	23	160	160	CD
cord-350019-4nlbu54e	240	24	,	,	,
cord-350019-4nlbu54e	240	25	161	161	CD
cord-350019-4nlbu54e	240	26	]	]	-RRB-
cord-350019-4nlbu54e	240	27	.	.	.
cord-350019-4nlbu54e	241	1	Paternal	paternal	JJ
cord-350019-4nlbu54e	241	2	imprinting	imprinting	NN
cord-350019-4nlbu54e	241	3	of	of	IN
cord-350019-4nlbu54e	241	4	UBE3A	UBE3A	NNP
cord-350019-4nlbu54e	241	5	requires	require	VBZ
cord-350019-4nlbu54e	241	6	the	the	DT
cord-350019-4nlbu54e	241	7	expression	expression	NN
cord-350019-4nlbu54e	241	8	of	of	IN
cord-350019-4nlbu54e	241	9	an	an	DT
cord-350019-4nlbu54e	241	10	antisense	antisense	NN
cord-350019-4nlbu54e	241	11	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	241	12	called	call	VBN
cord-350019-4nlbu54e	241	13	UBE3A	UBE3A	NNP
cord-350019-4nlbu54e	241	14	-	-	HYPH
cord-350019-4nlbu54e	241	15	ATS	ATS	NNP
cord-350019-4nlbu54e	241	16	.	.	.
cord-350019-4nlbu54e	242	1	Therefore	therefore	RB
cord-350019-4nlbu54e	242	2	,	,	,
cord-350019-4nlbu54e	242	3	targeting	target	VBG
cord-350019-4nlbu54e	242	4	the	the	DT
cord-350019-4nlbu54e	242	5	paternal	paternal	JJ
cord-350019-4nlbu54e	242	6	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	242	7	UBE3A	ube3a	CD
cord-350019-4nlbu54e	242	8	-	-	HYPH
cord-350019-4nlbu54e	242	9	ATS	ATS	NNP
cord-350019-4nlbu54e	242	10	using	use	VBG
cord-350019-4nlbu54e	242	11	ASOs	ASOs	NNP
cord-350019-4nlbu54e	242	12	leads	lead	VBZ
cord-350019-4nlbu54e	242	13	to	to	IN
cord-350019-4nlbu54e	242	14	de	de	NN
cord-350019-4nlbu54e	242	15	-	-	NN
cord-350019-4nlbu54e	242	16	repression	repression	NN
cord-350019-4nlbu54e	242	17	of	of	IN
cord-350019-4nlbu54e	242	18	expression	expression	NN
cord-350019-4nlbu54e	242	19	of	of	IN
cord-350019-4nlbu54e	242	20	paternal	paternal	JJ
cord-350019-4nlbu54e	242	21	UBE3A	ube3a	NN
cord-350019-4nlbu54e	242	22	,	,	,
cord-350019-4nlbu54e	242	23	allowing	allow	VBG
cord-350019-4nlbu54e	242	24	the	the	DT
cord-350019-4nlbu54e	242	25	rescue	rescue	NN
cord-350019-4nlbu54e	242	26	of	of	IN
cord-350019-4nlbu54e	242	27	the	the	DT
cord-350019-4nlbu54e	242	28	defective	defective	JJ
cord-350019-4nlbu54e	242	29	maternal	maternal	JJ
cord-350019-4nlbu54e	242	30	copy	copy	NN
cord-350019-4nlbu54e	242	31	[	[	-LRB-
cord-350019-4nlbu54e	242	32	161	161	CD
cord-350019-4nlbu54e	242	33	]	]	-RRB-
cord-350019-4nlbu54e	242	34	.	.	.
cord-350019-4nlbu54e	243	1	In	in	IN
cord-350019-4nlbu54e	243	2	a	a	DT
cord-350019-4nlbu54e	243	3	mouse	mouse	NN
cord-350019-4nlbu54e	243	4	model	model	NN
cord-350019-4nlbu54e	243	5	,	,	,
cord-350019-4nlbu54e	243	6	they	-PRON-	PRP
cord-350019-4nlbu54e	243	7	showed	show	VBD
cord-350019-4nlbu54e	243	8	that	that	IN
cord-350019-4nlbu54e	243	9	even	even	RB
cord-350019-4nlbu54e	243	10	partial	partial	JJ
cord-350019-4nlbu54e	243	11	restoration	restoration	NN
cord-350019-4nlbu54e	243	12	of	of	IN
cord-350019-4nlbu54e	243	13	the	the	DT
cord-350019-4nlbu54e	243	14	UBE3A	ube3a	CD
cord-350019-4nlbu54e	243	15	protein	protein	NN
cord-350019-4nlbu54e	243	16	expression	expression	NN
cord-350019-4nlbu54e	243	17	ameliorated	ameliorate	VBD
cord-350019-4nlbu54e	243	18	some	some	DT
cord-350019-4nlbu54e	243	19	cognitive	cognitive	JJ
cord-350019-4nlbu54e	243	20	deficits	deficit	NNS
cord-350019-4nlbu54e	243	21	associated	associate	VBN
cord-350019-4nlbu54e	243	22	with	with	IN
cord-350019-4nlbu54e	243	23	the	the	DT
cord-350019-4nlbu54e	243	24	disease	disease	NN
cord-350019-4nlbu54e	243	25	[	[	-LRB-
cord-350019-4nlbu54e	243	26	161	161	CD
cord-350019-4nlbu54e	243	27	]	]	-RRB-
cord-350019-4nlbu54e	243	28	.	.	.
cord-350019-4nlbu54e	244	1	Mechanistically	Mechanistically	NNP
cord-350019-4nlbu54e	244	2	,	,	,
cord-350019-4nlbu54e	244	3	it	-PRON-	PRP
cord-350019-4nlbu54e	244	4	is	be	VBZ
cord-350019-4nlbu54e	244	5	important	important	JJ
cord-350019-4nlbu54e	244	6	to	to	TO
cord-350019-4nlbu54e	244	7	dissect	dissect	VB
cord-350019-4nlbu54e	244	8	what	what	WP
cord-350019-4nlbu54e	244	9	features	feature	NNS
cord-350019-4nlbu54e	244	10	of	of	IN
cord-350019-4nlbu54e	244	11	a	a	DT
cord-350019-4nlbu54e	244	12	lncRNA	lncrna	NN
cord-350019-4nlbu54e	244	13	are	be	VBP
cord-350019-4nlbu54e	244	14	important	important	JJ
cord-350019-4nlbu54e	244	15	for	for	IN
cord-350019-4nlbu54e	244	16	its	-PRON-	PRP$
cord-350019-4nlbu54e	244	17	functionfor	functionfor	NN
cord-350019-4nlbu54e	244	18	example	example	NN
cord-350019-4nlbu54e	244	19	,	,	,
cord-350019-4nlbu54e	244	20	determining	determine	VBG
cord-350019-4nlbu54e	244	21	whether	whether	IN
cord-350019-4nlbu54e	244	22	the	the	DT
cord-350019-4nlbu54e	244	23	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	244	24	transcript	transcript	NN
cord-350019-4nlbu54e	244	25	is	be	VBZ
cord-350019-4nlbu54e	244	26	required	require	VBN
cord-350019-4nlbu54e	244	27	or	or	CC
cord-350019-4nlbu54e	244	28	whether	whether	IN
cord-350019-4nlbu54e	244	29	the	the	DT
cord-350019-4nlbu54e	244	30	mere	mere	JJ
cord-350019-4nlbu54e	244	31	act	act	NN
cord-350019-4nlbu54e	244	32	of	of	IN
cord-350019-4nlbu54e	244	33	transcription	transcription	NN
cord-350019-4nlbu54e	244	34	is	be	VBZ
cord-350019-4nlbu54e	244	35	the	the	DT
cord-350019-4nlbu54e	244	36	important	important	JJ
cord-350019-4nlbu54e	244	37	feature	feature	NN
cord-350019-4nlbu54e	244	38	needed	need	VBN
cord-350019-4nlbu54e	244	39	to	to	TO
cord-350019-4nlbu54e	244	40	mediate	mediate	VB
cord-350019-4nlbu54e	244	41	its	-PRON-	PRP$
cord-350019-4nlbu54e	244	42	function	function	NN
cord-350019-4nlbu54e	244	43	(	(	-LRB-
cord-350019-4nlbu54e	244	44	discussed	discuss	VBN
cord-350019-4nlbu54e	244	45	further	further	RB
cord-350019-4nlbu54e	244	46	below	below	RB
cord-350019-4nlbu54e	244	47	)	)	-RRB-
cord-350019-4nlbu54e	244	48	.	.	.
cord-350019-4nlbu54e	245	1	siRNAs	siRNAs	NNP
cord-350019-4nlbu54e	245	2	and	and	CC
cord-350019-4nlbu54e	245	3	ASOs	ASOs	NNP
cord-350019-4nlbu54e	245	4	are	be	VBP
cord-350019-4nlbu54e	245	5	thought	think	VBN
cord-350019-4nlbu54e	245	6	to	to	TO
cord-350019-4nlbu54e	245	7	inhibit	inhibit	VB
cord-350019-4nlbu54e	245	8	gene	gene	NN
cord-350019-4nlbu54e	245	9	expression	expression	NN
cord-350019-4nlbu54e	245	10	at	at	IN
cord-350019-4nlbu54e	245	11	the	the	DT
cord-350019-4nlbu54e	245	12	posttranscriptional	posttranscriptional	JJ
cord-350019-4nlbu54e	245	13	level	level	NN
cord-350019-4nlbu54e	245	14	,	,	,
cord-350019-4nlbu54e	245	15	albeit	albeit	IN
cord-350019-4nlbu54e	245	16	by	by	IN
cord-350019-4nlbu54e	245	17	different	different	JJ
cord-350019-4nlbu54e	245	18	mechanisms	mechanism	NNS
cord-350019-4nlbu54e	245	19	[	[	-LRB-
cord-350019-4nlbu54e	245	20	162	162	CD
cord-350019-4nlbu54e	245	21	,	,	,
cord-350019-4nlbu54e	245	22	163	163	CD
cord-350019-4nlbu54e	245	23	]	]	-RRB-
cord-350019-4nlbu54e	245	24	.	.	.
cord-350019-4nlbu54e	246	1	Nevertheless	nevertheless	RB
cord-350019-4nlbu54e	246	2	,	,	,
cord-350019-4nlbu54e	246	3	there	there	EX
cord-350019-4nlbu54e	246	4	are	be	VBP
cord-350019-4nlbu54e	246	5	examples	example	NNS
cord-350019-4nlbu54e	246	6	of	of	IN
cord-350019-4nlbu54e	246	7	siRNAs	siRNAs	NNP
cord-350019-4nlbu54e	246	8	(	(	-LRB-
cord-350019-4nlbu54e	246	9	reviewed	review	VBN
cord-350019-4nlbu54e	246	10	in	in	IN
cord-350019-4nlbu54e	246	11	[	[	-LRB-
cord-350019-4nlbu54e	246	12	164	164	CD
cord-350019-4nlbu54e	246	13	]	]	-RRB-
cord-350019-4nlbu54e	246	14	)	)	-RRB-
cord-350019-4nlbu54e	246	15	mediating	mediate	VBG
cord-350019-4nlbu54e	246	16	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	246	17	inhibition	inhibition	NN
cord-350019-4nlbu54e	246	18	.	.	.
cord-350019-4nlbu54e	247	1	Targeting	target	VBG
cord-350019-4nlbu54e	247	2	sequences	sequence	NNS
cord-350019-4nlbu54e	247	3	near	near	IN
cord-350019-4nlbu54e	247	4	the	the	DT
cord-350019-4nlbu54e	247	5	5′	5′	CD
cord-350019-4nlbu54e	247	6	end	end	NN
cord-350019-4nlbu54e	247	7	of	of	IN
cord-350019-4nlbu54e	247	8	the	the	DT
cord-350019-4nlbu54e	247	9	transcript	transcript	NN
cord-350019-4nlbu54e	247	10	can	can	MD
cord-350019-4nlbu54e	247	11	induce	induce	VB
cord-350019-4nlbu54e	247	12	the	the	DT
cord-350019-4nlbu54e	247	13	"	"	``
cord-350019-4nlbu54e	247	14	torpedo	torpedo	NN
cord-350019-4nlbu54e	247	15	-	-	HYPH
cord-350019-4nlbu54e	247	16	effect	effect	NN
cord-350019-4nlbu54e	247	17	,	,	,
cord-350019-4nlbu54e	247	18	"	"	''
cord-350019-4nlbu54e	247	19	resulting	result	VBG
cord-350019-4nlbu54e	247	20	in	in	IN
cord-350019-4nlbu54e	247	21	pre	pre	JJ
cord-350019-4nlbu54e	247	22	-	-	JJ
cord-350019-4nlbu54e	247	23	mature	mature	JJ
cord-350019-4nlbu54e	247	24	termination	termination	NN
cord-350019-4nlbu54e	247	25	of	of	IN
cord-350019-4nlbu54e	247	26	transcription	transcription	NN
cord-350019-4nlbu54e	247	27	[	[	-LRB-
cord-350019-4nlbu54e	247	28	165	165	CD
cord-350019-4nlbu54e	247	29	,	,	,
cord-350019-4nlbu54e	247	30	166	166	CD
cord-350019-4nlbu54e	247	31	]	]	-RRB-
cord-350019-4nlbu54e	247	32	.	.	.
cord-350019-4nlbu54e	248	1	Therefore	therefore	RB
cord-350019-4nlbu54e	248	2	,	,	,
cord-350019-4nlbu54e	248	3	when	when	WRB
cord-350019-4nlbu54e	248	4	targeting	target	VBG
cord-350019-4nlbu54e	248	5	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	248	6	with	with	IN
cord-350019-4nlbu54e	248	7	ASOs	ASOs	NNP
cord-350019-4nlbu54e	248	8	or	or	CC
cord-350019-4nlbu54e	248	9	siRNAs	siRNAs	NNP
cord-350019-4nlbu54e	248	10	,	,	,
cord-350019-4nlbu54e	248	11	it	-PRON-	PRP
cord-350019-4nlbu54e	248	12	's	be	VBZ
cord-350019-4nlbu54e	248	13	important	important	JJ
cord-350019-4nlbu54e	248	14	to	to	TO
cord-350019-4nlbu54e	248	15	consider	consider	VB
cord-350019-4nlbu54e	248	16	where	where	WRB
cord-350019-4nlbu54e	248	17	along	along	IN
cord-350019-4nlbu54e	248	18	with	with	IN
cord-350019-4nlbu54e	248	19	the	the	DT
cord-350019-4nlbu54e	248	20	transcript	transcript	NN
cord-350019-4nlbu54e	248	21	you	-PRON-	PRP
cord-350019-4nlbu54e	248	22	are	be	VBP
cord-350019-4nlbu54e	248	23	targeting	target	VBG
cord-350019-4nlbu54e	248	24	to	to	TO
cord-350019-4nlbu54e	248	25	ensure	ensure	VB
cord-350019-4nlbu54e	248	26	biological	biological	JJ
cord-350019-4nlbu54e	248	27	interpretation	interpretation	NN
cord-350019-4nlbu54e	248	28	of	of	IN
cord-350019-4nlbu54e	248	29	the	the	DT
cord-350019-4nlbu54e	248	30	ablation	ablation	NN
cord-350019-4nlbu54e	248	31	is	be	VBZ
cord-350019-4nlbu54e	248	32	correct	correct	JJ
cord-350019-4nlbu54e	248	33	.	.	.
cord-350019-4nlbu54e	249	1	The	the	DT
cord-350019-4nlbu54e	249	2	introduction	introduction	NN
cord-350019-4nlbu54e	249	3	of	of	IN
cord-350019-4nlbu54e	249	4	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	249	5	/	/	SYM
cord-350019-4nlbu54e	249	6	Cas9	Cas9	NNP
cord-350019-4nlbu54e	249	7	technology	technology	NN
cord-350019-4nlbu54e	249	8	has	have	VBZ
cord-350019-4nlbu54e	249	9	revolutionized	revolutionize	VBN
cord-350019-4nlbu54e	249	10	the	the	DT
cord-350019-4nlbu54e	249	11	field	field	NN
cord-350019-4nlbu54e	249	12	of	of	IN
cord-350019-4nlbu54e	249	13	functional	functional	JJ
cord-350019-4nlbu54e	249	14	genomics	genomic	NNS
cord-350019-4nlbu54e	249	15	by	by	IN
cord-350019-4nlbu54e	249	16	providing	provide	VBG
cord-350019-4nlbu54e	249	17	a	a	DT
cord-350019-4nlbu54e	249	18	novel	novel	JJ
cord-350019-4nlbu54e	249	19	tool	tool	NN
cord-350019-4nlbu54e	249	20	for	for	IN
cord-350019-4nlbu54e	249	21	interrogating	interrogate	VBG
cord-350019-4nlbu54e	249	22	gene	gene	NN
cord-350019-4nlbu54e	249	23	function	function	NN
cord-350019-4nlbu54e	249	24	.	.	.
cord-350019-4nlbu54e	250	1	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	250	2	/	/	SYM
cord-350019-4nlbu54e	250	3	Cas9	Cas9	NNP
cord-350019-4nlbu54e	250	4	is	be	VBZ
cord-350019-4nlbu54e	250	5	a	a	DT
cord-350019-4nlbu54e	250	6	deoxyribose	deoxyribose	JJ
cord-350019-4nlbu54e	250	7	nuclease	nuclease	NN
cord-350019-4nlbu54e	250	8	(	(	-LRB-
cord-350019-4nlbu54e	250	9	DNase	DNase	NNP
cord-350019-4nlbu54e	250	10	)	)	-RRB-
cord-350019-4nlbu54e	250	11	that	that	WDT
cord-350019-4nlbu54e	250	12	can	can	MD
cord-350019-4nlbu54e	250	13	be	be	VB
cord-350019-4nlbu54e	250	14	specifically	specifically	RB
cord-350019-4nlbu54e	250	15	targeted	target	VBN
cord-350019-4nlbu54e	250	16	to	to	IN
cord-350019-4nlbu54e	250	17	genomic	genomic	JJ
cord-350019-4nlbu54e	250	18	regions	region	NNS
cord-350019-4nlbu54e	250	19	via	via	IN
cord-350019-4nlbu54e	250	20	a	a	DT
cord-350019-4nlbu54e	250	21	guide	guide	NN
cord-350019-4nlbu54e	250	22	RNA	RNA	NNP
cord-350019-4nlbu54e	250	23	(	(	-LRB-
cord-350019-4nlbu54e	250	24	gRNA	gRNA	NNP
cord-350019-4nlbu54e	250	25	)	)	-RRB-
cord-350019-4nlbu54e	250	26	[	[	-LRB-
cord-350019-4nlbu54e	250	27	167	167	CD
cord-350019-4nlbu54e	250	28	,	,	,
cord-350019-4nlbu54e	250	29	168	168	CD
cord-350019-4nlbu54e	250	30	]	]	-RRB-
cord-350019-4nlbu54e	250	31	.	.	.
cord-350019-4nlbu54e	251	1	Targeting	target	VBG
cord-350019-4nlbu54e	251	2	of	of	IN
cord-350019-4nlbu54e	251	3	Cas9	Cas9	NNP
cord-350019-4nlbu54e	251	4	to	to	IN
cord-350019-4nlbu54e	251	5	a	a	DT
cord-350019-4nlbu54e	251	6	region	region	NN
cord-350019-4nlbu54e	251	7	results	result	VBZ
cord-350019-4nlbu54e	251	8	in	in	IN
cord-350019-4nlbu54e	251	9	a	a	DT
cord-350019-4nlbu54e	251	10	blunt	blunt	JJ
cord-350019-4nlbu54e	251	11	doublestranded	doublestranded	JJ
cord-350019-4nlbu54e	251	12	DNA	dna	NN
cord-350019-4nlbu54e	251	13	break	break	NN
cord-350019-4nlbu54e	251	14	that	that	WDT
cord-350019-4nlbu54e	251	15	engages	engage	VBZ
cord-350019-4nlbu54e	251	16	the	the	DT
cord-350019-4nlbu54e	251	17	cellular	cellular	JJ
cord-350019-4nlbu54e	251	18	Non	Non	NNP
cord-350019-4nlbu54e	251	19	-	-	NNP
cord-350019-4nlbu54e	251	20	Homologous	homologous	JJ
cord-350019-4nlbu54e	251	21	End	end	NN
cord-350019-4nlbu54e	251	22	-	-	HYPH
cord-350019-4nlbu54e	251	23	Joining	joining	NN
cord-350019-4nlbu54e	251	24	(	(	-LRB-
cord-350019-4nlbu54e	251	25	NHEJ	NHEJ	NNP
cord-350019-4nlbu54e	251	26	)	)	-RRB-
cord-350019-4nlbu54e	251	27	DNA	dna	NN
cord-350019-4nlbu54e	251	28	repair	repair	NN
cord-350019-4nlbu54e	251	29	pathway	pathway	NN
cord-350019-4nlbu54e	251	30	,	,	,
cord-350019-4nlbu54e	251	31	which	which	WDT
cord-350019-4nlbu54e	251	32	promotes	promote	VBZ
cord-350019-4nlbu54e	251	33	imprecise	imprecise	JJ
cord-350019-4nlbu54e	251	34	repair	repair	NN
cord-350019-4nlbu54e	251	35	,	,	,
cord-350019-4nlbu54e	251	36	yielding	yield	VBG
cord-350019-4nlbu54e	251	37	small	small	JJ
cord-350019-4nlbu54e	251	38	deletions	deletion	NNS
cord-350019-4nlbu54e	251	39	in	in	IN
cord-350019-4nlbu54e	251	40	the	the	DT
cord-350019-4nlbu54e	251	41	repaired	repair	VBN
cord-350019-4nlbu54e	251	42	sequence	sequence	NN
cord-350019-4nlbu54e	251	43	.	.	.
cord-350019-4nlbu54e	252	1	These	these	DT
cord-350019-4nlbu54e	252	2	small	small	JJ
cord-350019-4nlbu54e	252	3	deletions	deletion	NNS
cord-350019-4nlbu54e	252	4	result	result	VBP
cord-350019-4nlbu54e	252	5	in	in	IN
cord-350019-4nlbu54e	252	6	a	a	DT
cord-350019-4nlbu54e	252	7	frame	frame	NN
cord-350019-4nlbu54e	252	8	-	-	HYPH
cord-350019-4nlbu54e	252	9	shift	shift	NN
cord-350019-4nlbu54e	252	10	that	that	WDT
cord-350019-4nlbu54e	252	11	disrupts	disrupt	VBZ
cord-350019-4nlbu54e	252	12	the	the	DT
cord-350019-4nlbu54e	252	13	ORFs	orfs	NN
cord-350019-4nlbu54e	252	14	within	within	IN
cord-350019-4nlbu54e	252	15	coding	code	VBG
cord-350019-4nlbu54e	252	16	genes	gene	NNS
cord-350019-4nlbu54e	252	17	,	,	,
cord-350019-4nlbu54e	252	18	thereby	thereby	RB
cord-350019-4nlbu54e	252	19	disrupting	disrupt	VBG
cord-350019-4nlbu54e	252	20	protein	protein	NN
cord-350019-4nlbu54e	252	21	synthesis	synthesis	NN
cord-350019-4nlbu54e	252	22	.	.	.
cord-350019-4nlbu54e	253	1	LncRNAs	lncrna	NNS
cord-350019-4nlbu54e	253	2	do	do	VBP
cord-350019-4nlbu54e	253	3	not	not	RB
cord-350019-4nlbu54e	253	4	contain	contain	VB
cord-350019-4nlbu54e	253	5	ORFs	ORFs	NNP
cord-350019-4nlbu54e	253	6	and	and	CC
cord-350019-4nlbu54e	253	7	span	span	VB
cord-350019-4nlbu54e	253	8	tens	ten	NNS
cord-350019-4nlbu54e	253	9	of	of	IN
cord-350019-4nlbu54e	253	10	kilobases	kilobase	NNS
cord-350019-4nlbu54e	253	11	of	of	IN
cord-350019-4nlbu54e	253	12	sequence	sequence	NN
cord-350019-4nlbu54e	253	13	in	in	IN
cord-350019-4nlbu54e	253	14	size	size	NN
cord-350019-4nlbu54e	253	15	.	.	.
cord-350019-4nlbu54e	254	1	As	as	IN
cord-350019-4nlbu54e	254	2	such	such	JJ
cord-350019-4nlbu54e	254	3	,	,	,
cord-350019-4nlbu54e	254	4	targeting	target	VBG
cord-350019-4nlbu54e	254	5	them	-PRON-	PRP
cord-350019-4nlbu54e	254	6	with	with	IN
cord-350019-4nlbu54e	254	7	a	a	DT
cord-350019-4nlbu54e	254	8	single	single	JJ
cord-350019-4nlbu54e	254	9	gRNA	grna	NN
cord-350019-4nlbu54e	254	10	is	be	VBZ
cord-350019-4nlbu54e	254	11	thought	think	VBN
cord-350019-4nlbu54e	254	12	to	to	TO
cord-350019-4nlbu54e	254	13	be	be	VB
cord-350019-4nlbu54e	254	14	insufficient	insufficient	JJ
cord-350019-4nlbu54e	254	15	to	to	TO
cord-350019-4nlbu54e	254	16	disrupt	disrupt	VB
cord-350019-4nlbu54e	254	17	their	-PRON-	PRP$
cord-350019-4nlbu54e	254	18	function	function	NN
cord-350019-4nlbu54e	254	19	[	[	-LRB-
cord-350019-4nlbu54e	254	20	169	169	CD
cord-350019-4nlbu54e	254	21	]	]	-RRB-
cord-350019-4nlbu54e	254	22	.	.	.
cord-350019-4nlbu54e	255	1	An	an	DT
cord-350019-4nlbu54e	255	2	alternative	alternative	JJ
cord-350019-4nlbu54e	255	3	application	application	NN
cord-350019-4nlbu54e	255	4	of	of	IN
cord-350019-4nlbu54e	255	5	Cas9	Cas9	NNP
cord-350019-4nlbu54e	255	6	that	that	WDT
cord-350019-4nlbu54e	255	7	has	have	VBZ
cord-350019-4nlbu54e	255	8	proven	prove	VBN
cord-350019-4nlbu54e	255	9	effective	effective	JJ
cord-350019-4nlbu54e	255	10	for	for	IN
cord-350019-4nlbu54e	255	11	targeting	target	VBG
cord-350019-4nlbu54e	255	12	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	255	13	involves	involve	NNS
cord-350019-4nlbu54e	255	14	using	use	VBG
cord-350019-4nlbu54e	255	15	two	two	CD
cord-350019-4nlbu54e	255	16	gRNAs	gRNAs	NNPS
cord-350019-4nlbu54e	255	17	flanking	flank	VBG
cord-350019-4nlbu54e	255	18	the	the	DT
cord-350019-4nlbu54e	255	19	lncRNA	lncrna	NN
cord-350019-4nlbu54e	255	20	region	region	NN
cord-350019-4nlbu54e	255	21	of	of	IN
cord-350019-4nlbu54e	255	22	interest	interest	NN
cord-350019-4nlbu54e	255	23	to	to	TO
cord-350019-4nlbu54e	255	24	induce	induce	VB
cord-350019-4nlbu54e	255	25	deletion	deletion	NN
cord-350019-4nlbu54e	255	26	of	of	IN
cord-350019-4nlbu54e	255	27	the	the	DT
cord-350019-4nlbu54e	255	28	entire	entire	JJ
cord-350019-4nlbu54e	255	29	locus	locus	NN
cord-350019-4nlbu54e	255	30	(	(	-LRB-
cord-350019-4nlbu54e	255	31	Fig	Fig	NNP
cord-350019-4nlbu54e	255	32	.	.	.
cord-350019-4nlbu54e	255	33	3E	3E	NNP
cord-350019-4nlbu54e	255	34	)	)	-RRB-
cord-350019-4nlbu54e	255	35	.	.	.
cord-350019-4nlbu54e	256	1	The	the	DT
cord-350019-4nlbu54e	256	2	main	main	JJ
cord-350019-4nlbu54e	256	3	advantage	advantage	NN
cord-350019-4nlbu54e	256	4	of	of	IN
cord-350019-4nlbu54e	256	5	deleting	delete	VBG
cord-350019-4nlbu54e	256	6	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	256	7	is	be	VBZ
cord-350019-4nlbu54e	256	8	obtaining	obtain	VBG
cord-350019-4nlbu54e	256	9	complete	complete	JJ
cord-350019-4nlbu54e	256	10	loss	loss	NN
cord-350019-4nlbu54e	256	11	-	-	HYPH
cord-350019-4nlbu54e	256	12	of	of	IN
cord-350019-4nlbu54e	256	13	-	-	HYPH
cord-350019-4nlbu54e	256	14	function	function	NN
cord-350019-4nlbu54e	256	15	,	,	,
cord-350019-4nlbu54e	256	16	as	as	IN
cord-350019-4nlbu54e	256	17	demonstrated	demonstrate	VBN
cord-350019-4nlbu54e	256	18	in	in	IN
cord-350019-4nlbu54e	256	19	a	a	DT
cord-350019-4nlbu54e	256	20	recent	recent	JJ
cord-350019-4nlbu54e	256	21	study	study	NN
cord-350019-4nlbu54e	256	22	that	that	WDT
cord-350019-4nlbu54e	256	23	performed	perform	VBD
cord-350019-4nlbu54e	256	24	a	a	DT
cord-350019-4nlbu54e	256	25	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	256	26	-	-	HYPH
cord-350019-4nlbu54e	256	27	mediated	mediate	VBN
cord-350019-4nlbu54e	256	28	deletion	deletion	NN
cord-350019-4nlbu54e	256	29	-	-	HYPH
cord-350019-4nlbu54e	256	30	screen	screen	NN
cord-350019-4nlbu54e	256	31	to	to	TO
cord-350019-4nlbu54e	256	32	identify	identify	VB
cord-350019-4nlbu54e	256	33	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	256	34	that	that	WDT
cord-350019-4nlbu54e	256	35	positively	positively	RB
cord-350019-4nlbu54e	256	36	and	and	CC
cord-350019-4nlbu54e	256	37	negatively	negatively	RB
cord-350019-4nlbu54e	256	38	regulate	regulate	VB
cord-350019-4nlbu54e	256	39	cancer	cancer	NN
cord-350019-4nlbu54e	256	40	growth	growth	NN
cord-350019-4nlbu54e	256	41	[	[	-LRB-
cord-350019-4nlbu54e	256	42	170	170	CD
cord-350019-4nlbu54e	256	43	]	]	-RRB-
cord-350019-4nlbu54e	256	44	.	.	.
cord-350019-4nlbu54e	257	1	On	on	IN
cord-350019-4nlbu54e	257	2	the	the	DT
cord-350019-4nlbu54e	257	3	other	other	JJ
cord-350019-4nlbu54e	257	4	hand	hand	NN
cord-350019-4nlbu54e	257	5	,	,	,
cord-350019-4nlbu54e	257	6	deletion	deletion	NN
cord-350019-4nlbu54e	257	7	of	of	IN
cord-350019-4nlbu54e	257	8	the	the	DT
cord-350019-4nlbu54e	257	9	DNA	dna	NN
cord-350019-4nlbu54e	257	10	sequence	sequence	NN
cord-350019-4nlbu54e	257	11	may	may	MD
cord-350019-4nlbu54e	257	12	result	result	VB
cord-350019-4nlbu54e	257	13	in	in	IN
cord-350019-4nlbu54e	257	14	an	an	DT
cord-350019-4nlbu54e	257	15	inability	inability	NN
cord-350019-4nlbu54e	257	16	to	to	TO
cord-350019-4nlbu54e	257	17	resolve	resolve	VB
cord-350019-4nlbu54e	257	18	whether	whether	IN
cord-350019-4nlbu54e	257	19	a	a	DT
cord-350019-4nlbu54e	257	20	phenotype	phenotype	NN
cord-350019-4nlbu54e	257	21	is	be	VBZ
cord-350019-4nlbu54e	257	22	due	due	JJ
cord-350019-4nlbu54e	257	23	to	to	IN
cord-350019-4nlbu54e	257	24	loss	loss	NN
cord-350019-4nlbu54e	257	25	of	of	IN
cord-350019-4nlbu54e	257	26	lncRNA	lncrna	NN
cord-350019-4nlbu54e	257	27	production	production	NN
cord-350019-4nlbu54e	257	28	or	or	CC
cord-350019-4nlbu54e	257	29	loss	loss	NN
cord-350019-4nlbu54e	257	30	of	of	IN
cord-350019-4nlbu54e	257	31	DNA	dna	NN
cord-350019-4nlbu54e	257	32	sequence	sequence	NN
cord-350019-4nlbu54e	257	33	(	(	-LRB-
cord-350019-4nlbu54e	257	34	discussed	discuss	VBN
cord-350019-4nlbu54e	257	35	below	below	RB
cord-350019-4nlbu54e	257	36	)	)	-RRB-
cord-350019-4nlbu54e	257	37	[	[	-LRB-
cord-350019-4nlbu54e	257	38	171	171	CD
cord-350019-4nlbu54e	257	39	]	]	-RRB-
cord-350019-4nlbu54e	257	40	.	.	.
cord-350019-4nlbu54e	258	1	In	in	IN
cord-350019-4nlbu54e	258	2	an	an	DT
cord-350019-4nlbu54e	258	3	alternative	alternative	JJ
cord-350019-4nlbu54e	258	4	approach	approach	NN
cord-350019-4nlbu54e	258	5	,	,	,
cord-350019-4nlbu54e	258	6	Liu	Liu	NNP
cord-350019-4nlbu54e	258	7	and	and	CC
cord-350019-4nlbu54e	258	8	colleagues	colleague	NNS
cord-350019-4nlbu54e	258	9	recently	recently	RB
cord-350019-4nlbu54e	258	10	performed	perform	VBD
cord-350019-4nlbu54e	258	11	a	a	DT
cord-350019-4nlbu54e	258	12	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	258	13	screen	screen	NN
cord-350019-4nlbu54e	258	14	targeting	target	VBG
cord-350019-4nlbu54e	258	15	the	the	DT
cord-350019-4nlbu54e	258	16	splice	splice	NN
cord-350019-4nlbu54e	258	17	sites	site	NNS
cord-350019-4nlbu54e	258	18	of	of	IN
cord-350019-4nlbu54e	258	19	over	over	IN
cord-350019-4nlbu54e	258	20	10-thousand	10-thousand	CD
cord-350019-4nlbu54e	258	21	lncRNAs	lncRNAs	NNPS
cord-350019-4nlbu54e	258	22	and	and	CC
cord-350019-4nlbu54e	258	23	identified	identify	VBD
cord-350019-4nlbu54e	258	24	230	230	CD
cord-350019-4nlbu54e	258	25	lncRNAs	lncrna	NNS
cord-350019-4nlbu54e	258	26	that	that	WDT
cord-350019-4nlbu54e	258	27	proved	prove	VBD
cord-350019-4nlbu54e	258	28	essential	essential	JJ
cord-350019-4nlbu54e	258	29	for	for	IN
cord-350019-4nlbu54e	258	30	viability	viability	NN
cord-350019-4nlbu54e	258	31	(	(	-LRB-
cord-350019-4nlbu54e	258	32	Fig	Fig	NNP
cord-350019-4nlbu54e	258	33	.	.	.
cord-350019-4nlbu54e	258	34	3D	3D	NNP
cord-350019-4nlbu54e	258	35	)	)	-RRB-
cord-350019-4nlbu54e	258	36	[	[	-LRB-
cord-350019-4nlbu54e	258	37	172	172	CD
cord-350019-4nlbu54e	258	38	]	]	-RRB-
cord-350019-4nlbu54e	258	39	.	.	.
cord-350019-4nlbu54e	259	1	Targeting	target	VBG
cord-350019-4nlbu54e	259	2	of	of	IN
cord-350019-4nlbu54e	259	3	splice	splice	NN
cord-350019-4nlbu54e	259	4	sites	site	NNS
cord-350019-4nlbu54e	259	5	has	have	VBZ
cord-350019-4nlbu54e	259	6	also	also	RB
cord-350019-4nlbu54e	259	7	been	be	VBN
cord-350019-4nlbu54e	259	8	shown	show	VBN
cord-350019-4nlbu54e	259	9	to	to	TO
cord-350019-4nlbu54e	259	10	induce	induce	VB
cord-350019-4nlbu54e	259	11	exon	exon	NN
cord-350019-4nlbu54e	259	12	skipping	skip	VBG
cord-350019-4nlbu54e	259	13	within	within	IN
cord-350019-4nlbu54e	259	14	coding	code	VBG
cord-350019-4nlbu54e	259	15	genes	gene	NNS
cord-350019-4nlbu54e	259	16	[	[	-LRB-
cord-350019-4nlbu54e	259	17	173	173	CD
cord-350019-4nlbu54e	259	18	]	]	-RRB-
cord-350019-4nlbu54e	259	19	.	.	.
cord-350019-4nlbu54e	260	1	LncRNAs	lncrna	NNS
cord-350019-4nlbu54e	260	2	have	have	VBP
cord-350019-4nlbu54e	260	3	many	many	JJ
cord-350019-4nlbu54e	260	4	of	of	IN
cord-350019-4nlbu54e	260	5	the	the	DT
cord-350019-4nlbu54e	260	6	same	same	JJ
cord-350019-4nlbu54e	260	7	regulatory	regulatory	JJ
cord-350019-4nlbu54e	260	8	elements	element	NNS
cord-350019-4nlbu54e	260	9	as	as	IN
cord-350019-4nlbu54e	260	10	coding	code	VBG
cord-350019-4nlbu54e	260	11	genes	gene	NNS
cord-350019-4nlbu54e	260	12	.	.	.
cord-350019-4nlbu54e	261	1	Hence	hence	RB
cord-350019-4nlbu54e	261	2	future	future	JJ
cord-350019-4nlbu54e	261	3	studies	study	NNS
cord-350019-4nlbu54e	261	4	may	may	MD
cord-350019-4nlbu54e	261	5	opt	opt	VB
cord-350019-4nlbu54e	261	6	to	to	TO
cord-350019-4nlbu54e	261	7	target	target	VB
cord-350019-4nlbu54e	261	8	TF	TF	NNP
cord-350019-4nlbu54e	261	9	binding	bind	VBG
cord-350019-4nlbu54e	261	10	sites	site	NNS
cord-350019-4nlbu54e	261	11	,	,	,
cord-350019-4nlbu54e	261	12	secondary	secondary	JJ
cord-350019-4nlbu54e	261	13	structure	structure	NN
cord-350019-4nlbu54e	261	14	and/or	and/or	CC
cord-350019-4nlbu54e	261	15	polyadenylation	polyadenylation	NN
cord-350019-4nlbu54e	261	16	sites	site	NNS
cord-350019-4nlbu54e	261	17	as	as	IN
cord-350019-4nlbu54e	261	18	a	a	DT
cord-350019-4nlbu54e	261	19	way	way	NN
cord-350019-4nlbu54e	261	20	to	to	IN
cord-350019-4nlbu54e	261	21	more	more	RBR
cord-350019-4nlbu54e	261	22	finely	finely	RB
cord-350019-4nlbu54e	261	23	dissect	dissect	VB
cord-350019-4nlbu54e	261	24	the	the	DT
cord-350019-4nlbu54e	261	25	functional	functional	JJ
cord-350019-4nlbu54e	261	26	portions	portion	NNS
cord-350019-4nlbu54e	261	27	of	of	IN
cord-350019-4nlbu54e	261	28	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	261	29	.	.	.
cord-350019-4nlbu54e	262	1	The	the	DT
cord-350019-4nlbu54e	262	2	ease	ease	NN
cord-350019-4nlbu54e	262	3	in	in	IN
cord-350019-4nlbu54e	262	4	which	which	WDT
cord-350019-4nlbu54e	262	5	Cas9	Cas9	NNP
cord-350019-4nlbu54e	262	6	can	can	MD
cord-350019-4nlbu54e	262	7	be	be	VB
cord-350019-4nlbu54e	262	8	targeted	target	VBN
cord-350019-4nlbu54e	262	9	to	to	IN
cord-350019-4nlbu54e	262	10	specific	specific	JJ
cord-350019-4nlbu54e	262	11	genomic	genomic	JJ
cord-350019-4nlbu54e	262	12	regions	region	NNS
cord-350019-4nlbu54e	262	13	sparked	spark	VBD
cord-350019-4nlbu54e	262	14	the	the	DT
cord-350019-4nlbu54e	262	15	development	development	NN
cord-350019-4nlbu54e	262	16	of	of	IN
cord-350019-4nlbu54e	262	17	a	a	DT
cord-350019-4nlbu54e	262	18	modified	modify	VBN
cord-350019-4nlbu54e	262	19	(	(	-LRB-
cord-350019-4nlbu54e	262	20	catalytically	catalytically	RB
cord-350019-4nlbu54e	262	21	inactivated	inactivate	VBN
cord-350019-4nlbu54e	262	22	)	)	-RRB-
cord-350019-4nlbu54e	262	23	version	version	NN
cord-350019-4nlbu54e	262	24	of	of	IN
cord-350019-4nlbu54e	262	25	the	the	DT
cord-350019-4nlbu54e	262	26	protein	protein	NN
cord-350019-4nlbu54e	262	27	fused	fuse	VBN
cord-350019-4nlbu54e	262	28	to	to	IN
cord-350019-4nlbu54e	262	29	the	the	DT
cord-350019-4nlbu54e	262	30	KRAB	krab	NN
cord-350019-4nlbu54e	263	1	(	(	-LRB-
cord-350019-4nlbu54e	263	2	Krüppel	Krüppel	NNP
cord-350019-4nlbu54e	263	3	associated	associate	VBD
cord-350019-4nlbu54e	263	4	box	box	NN
cord-350019-4nlbu54e	263	5	)	)	-RRB-
cord-350019-4nlbu54e	264	1	chromatin	chromatin	NN
cord-350019-4nlbu54e	264	2	-	-	HYPH
cord-350019-4nlbu54e	264	3	silencing	silence	VBG
cord-350019-4nlbu54e	264	4	domain	domain	NN
cord-350019-4nlbu54e	264	5	termed	term	VBN
cord-350019-4nlbu54e	264	6	CRISPRi	CRISPRi	NNS
cord-350019-4nlbu54e	264	7	[	[	-LRB-
cord-350019-4nlbu54e	264	8	174	174	CD
cord-350019-4nlbu54e	264	9	,	,	,
cord-350019-4nlbu54e	264	10	175	175	CD
cord-350019-4nlbu54e	264	11	]	]	-RRB-
cord-350019-4nlbu54e	265	1	(	(	-LRB-
cord-350019-4nlbu54e	265	2	Fig	Fig	NNP
cord-350019-4nlbu54e	265	3	.	.	.
cord-350019-4nlbu54e	265	4	3C	3C	NNP
cord-350019-4nlbu54e	265	5	)	)	-RRB-
cord-350019-4nlbu54e	265	6	.	.	.
cord-350019-4nlbu54e	266	1	CRISPRi	CRISPRi	NNS
cord-350019-4nlbu54e	266	2	can	can	MD
cord-350019-4nlbu54e	266	3	be	be	VB
cord-350019-4nlbu54e	266	4	used	use	VBN
cord-350019-4nlbu54e	266	5	to	to	TO
cord-350019-4nlbu54e	266	6	target	target	VB
cord-350019-4nlbu54e	266	7	both	both	DT
cord-350019-4nlbu54e	266	8	coding	code	VBG
cord-350019-4nlbu54e	266	9	and	and	CC
cord-350019-4nlbu54e	266	10	noncoding	noncoding	JJ
cord-350019-4nlbu54e	266	11	genes	gene	NNS
cord-350019-4nlbu54e	266	12	(	(	-LRB-
cord-350019-4nlbu54e	266	13	such	such	JJ
cord-350019-4nlbu54e	266	14	as	as	IN
cord-350019-4nlbu54e	266	15	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	266	16	)	)	-RRB-
cord-350019-4nlbu54e	266	17	,	,	,
cord-350019-4nlbu54e	266	18	triggering	trigger	VBG
cord-350019-4nlbu54e	266	19	localized	localize	VBN
cord-350019-4nlbu54e	266	20	heterochromatin	heterochromatin	NN
cord-350019-4nlbu54e	266	21	-	-	HYPH
cord-350019-4nlbu54e	266	22	silencing	silencing	NN
cord-350019-4nlbu54e	266	23	at	at	IN
cord-350019-4nlbu54e	266	24	the	the	DT
cord-350019-4nlbu54e	266	25	transcription	transcription	NN
cord-350019-4nlbu54e	266	26	start	start	NN
cord-350019-4nlbu54e	266	27	site	site	NN
cord-350019-4nlbu54e	266	28	(	(	-LRB-
cord-350019-4nlbu54e	266	29	TSS	TSS	NNP
cord-350019-4nlbu54e	266	30	)	)	-RRB-
cord-350019-4nlbu54e	266	31	[	[	-LRB-
cord-350019-4nlbu54e	266	32	176	176	CD
cord-350019-4nlbu54e	266	33	]	]	-RRB-
cord-350019-4nlbu54e	266	34	.	.	.
cord-350019-4nlbu54e	267	1	Unlike	unlike	IN
cord-350019-4nlbu54e	267	2	RNAi	RNAi	NNP
cord-350019-4nlbu54e	267	3	,	,	,
cord-350019-4nlbu54e	267	4	the	the	DT
cord-350019-4nlbu54e	267	5	transcription	transcription	NN
cord-350019-4nlbu54e	267	6	-	-	HYPH
cord-350019-4nlbu54e	267	7	based	base	VBN
cord-350019-4nlbu54e	267	8	inhibition	inhibition	NN
cord-350019-4nlbu54e	267	9	by	by	IN
cord-350019-4nlbu54e	267	10	CRISPRi	CRISPRi	NNS
cord-350019-4nlbu54e	267	11	offers	offer	VBZ
cord-350019-4nlbu54e	267	12	the	the	DT
cord-350019-4nlbu54e	267	13	ability	ability	NN
cord-350019-4nlbu54e	267	14	to	to	TO
cord-350019-4nlbu54e	267	15	efficiently	efficiently	RB
cord-350019-4nlbu54e	267	16	target	target	VB
cord-350019-4nlbu54e	267	17	lncRNAs	lncrnas	RB
cord-350019-4nlbu54e	267	18	regardless	regardless	RB
cord-350019-4nlbu54e	267	19	of	of	IN
cord-350019-4nlbu54e	267	20	their	-PRON-	PRP$
cord-350019-4nlbu54e	267	21	localization	localization	NN
cord-350019-4nlbu54e	267	22	in	in	IN
cord-350019-4nlbu54e	267	23	the	the	DT
cord-350019-4nlbu54e	267	24	cell	cell	NN
cord-350019-4nlbu54e	267	25	.	.	.
cord-350019-4nlbu54e	268	1	Gilbert	Gilbert	NNP
cord-350019-4nlbu54e	268	2	et	et	NNP
cord-350019-4nlbu54e	268	3	al	al	NNP
cord-350019-4nlbu54e	268	4	.	.	NNP
cord-350019-4nlbu54e	268	5	have	have	VBP
cord-350019-4nlbu54e	268	6	shown	show	VBN
cord-350019-4nlbu54e	268	7	maximum	maximum	JJ
cord-350019-4nlbu54e	268	8	knock	knock	VB
cord-350019-4nlbu54e	268	9	-	-	HYPH
cord-350019-4nlbu54e	268	10	down	down	RP
cord-350019-4nlbu54e	268	11	efficiency	efficiency	NN
cord-350019-4nlbu54e	268	12	when	when	WRB
cord-350019-4nlbu54e	268	13	targeting	target	VBG
cord-350019-4nlbu54e	268	14	regions	region	NNS
cord-350019-4nlbu54e	268	15	+50	+50	XX
cord-350019-4nlbu54e	268	16	to	to	IN
cord-350019-4nlbu54e	268	17	+500	+500	NNP
cord-350019-4nlbu54e	268	18	nucleotides	nucleotide	NNS
cord-350019-4nlbu54e	268	19	relative	relative	JJ
cord-350019-4nlbu54e	268	20	to	to	IN
cord-350019-4nlbu54e	268	21	the	the	DT
cord-350019-4nlbu54e	268	22	transcription	transcription	NN
cord-350019-4nlbu54e	268	23	start	start	NN
cord-350019-4nlbu54e	268	24	site	site	NN
cord-350019-4nlbu54e	268	25	(	(	-LRB-
cord-350019-4nlbu54e	268	26	TSS	TSS	NNP
cord-350019-4nlbu54e	268	27	)	)	-RRB-
cord-350019-4nlbu54e	268	28	[	[	-LRB-
cord-350019-4nlbu54e	268	29	174	174	CD
cord-350019-4nlbu54e	268	30	]	]	-RRB-
cord-350019-4nlbu54e	268	31	.	.	.
cord-350019-4nlbu54e	269	1	However	however	RB
cord-350019-4nlbu54e	269	2	,	,	,
cord-350019-4nlbu54e	269	3	CRISPRi	CRISPRi	NNP
cord-350019-4nlbu54e	269	4	is	be	VBZ
cord-350019-4nlbu54e	269	5	limited	limit	VBN
cord-350019-4nlbu54e	269	6	by	by	IN
cord-350019-4nlbu54e	269	7	the	the	DT
cord-350019-4nlbu54e	269	8	availability	availability	NN
cord-350019-4nlbu54e	269	9	of	of	IN
cord-350019-4nlbu54e	269	10	an	an	DT
cord-350019-4nlbu54e	269	11	accurately	accurately	RB
cord-350019-4nlbu54e	269	12	annotated	annotate	VBN
cord-350019-4nlbu54e	269	13	TSS	TSS	NNP
cord-350019-4nlbu54e	269	14	,	,	,
cord-350019-4nlbu54e	269	15	particularly	particularly	RB
cord-350019-4nlbu54e	269	16	for	for	IN
cord-350019-4nlbu54e	269	17	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	269	18	.	.	.
cord-350019-4nlbu54e	270	1	Incorporating	incorporate	VBG
cord-350019-4nlbu54e	270	2	CAGE	cage	NN
cord-350019-4nlbu54e	270	3	-	-	HYPH
cord-350019-4nlbu54e	270	4	seq	seq	NN
cord-350019-4nlbu54e	270	5	,	,	,
cord-350019-4nlbu54e	270	6	Gro	Gro	NNP
cord-350019-4nlbu54e	270	7	-	-	HYPH
cord-350019-4nlbu54e	270	8	seq	seq	NNP
cord-350019-4nlbu54e	270	9	and/or	and/or	CC
cord-350019-4nlbu54e	270	10	ChIP	chip	NN
cord-350019-4nlbu54e	270	11	-	-	HYPH
cord-350019-4nlbu54e	270	12	seq	seq	NN
cord-350019-4nlbu54e	270	13	data	datum	NNS
cord-350019-4nlbu54e	270	14	into	into	IN
cord-350019-4nlbu54e	270	15	gRNA	grna	NN
cord-350019-4nlbu54e	270	16	design	design	NN
cord-350019-4nlbu54e	270	17	may	may	MD
cord-350019-4nlbu54e	270	18	improve	improve	VB
cord-350019-4nlbu54e	270	19	efficient	efficient	JJ
cord-350019-4nlbu54e	270	20	targeting	targeting	NN
cord-350019-4nlbu54e	270	21	of	of	IN
cord-350019-4nlbu54e	270	22	a	a	DT
cord-350019-4nlbu54e	270	23	lncRNA	lncrna	NN
cord-350019-4nlbu54e	270	24	of	of	IN
cord-350019-4nlbu54e	270	25	interest	interest	NN
cord-350019-4nlbu54e	270	26	[	[	-LRB-
cord-350019-4nlbu54e	270	27	177	177	CD
cord-350019-4nlbu54e	270	28	]	]	-RRB-
cord-350019-4nlbu54e	270	29	.	.	.
cord-350019-4nlbu54e	271	1	Nevertheless	nevertheless	RB
cord-350019-4nlbu54e	271	2	,	,	,
cord-350019-4nlbu54e	271	3	a	a	DT
cord-350019-4nlbu54e	271	4	recent	recent	JJ
cord-350019-4nlbu54e	271	5	study	study	NN
cord-350019-4nlbu54e	271	6	from	from	IN
cord-350019-4nlbu54e	271	7	the	the	DT
cord-350019-4nlbu54e	271	8	Weissman	Weissman	NNP
cord-350019-4nlbu54e	271	9	and	and	CC
cord-350019-4nlbu54e	271	10	Lim	Lim	NNP
cord-350019-4nlbu54e	271	11	groups	group	NNS
cord-350019-4nlbu54e	271	12	utilized	utilize	VBD
cord-350019-4nlbu54e	271	13	CRISPRi	CRISPRi	NNS
cord-350019-4nlbu54e	271	14	to	to	TO
cord-350019-4nlbu54e	271	15	target	target	VB
cord-350019-4nlbu54e	271	16	16,401	16,401	CD
cord-350019-4nlbu54e	271	17	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	271	18	loci	locus	NNS
cord-350019-4nlbu54e	271	19	in	in	IN
cord-350019-4nlbu54e	271	20	7	7	CD
cord-350019-4nlbu54e	271	21	diverse	diverse	JJ
cord-350019-4nlbu54e	271	22	cell	cell	NN
cord-350019-4nlbu54e	271	23	lines	line	NNS
cord-350019-4nlbu54e	271	24	and	and	CC
cord-350019-4nlbu54e	271	25	identified	identify	VBD
cord-350019-4nlbu54e	271	26	hundreds	hundred	NNS
cord-350019-4nlbu54e	271	27	of	of	IN
cord-350019-4nlbu54e	271	28	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	271	29	required	require	VBN
cord-350019-4nlbu54e	271	30	for	for	IN
cord-350019-4nlbu54e	271	31	cell	cell	NN
cord-350019-4nlbu54e	271	32	growth	growth	NN
cord-350019-4nlbu54e	271	33	[	[	-LRB-
cord-350019-4nlbu54e	271	34	96	96	CD
cord-350019-4nlbu54e	271	35	]	]	-RRB-
cord-350019-4nlbu54e	271	36	.	.	.
cord-350019-4nlbu54e	272	1	Therefore	therefore	RB
cord-350019-4nlbu54e	272	2	,	,	,
cord-350019-4nlbu54e	272	3	despite	despite	IN
cord-350019-4nlbu54e	272	4	its	-PRON-	PRP$
cord-350019-4nlbu54e	272	5	caveats	caveat	NNS
cord-350019-4nlbu54e	272	6	,	,	,
cord-350019-4nlbu54e	272	7	it	-PRON-	PRP
cord-350019-4nlbu54e	272	8	appears	appear	VBZ
cord-350019-4nlbu54e	272	9	that	that	IN
cord-350019-4nlbu54e	272	10	CRISPRi	CRISPRi	NNS
cord-350019-4nlbu54e	272	11	can	can	MD
cord-350019-4nlbu54e	272	12	be	be	VB
cord-350019-4nlbu54e	272	13	a	a	DT
cord-350019-4nlbu54e	272	14	useful	useful	JJ
cord-350019-4nlbu54e	272	15	and	and	CC
cord-350019-4nlbu54e	272	16	powerful	powerful	JJ
cord-350019-4nlbu54e	272	17	tool	tool	NN
cord-350019-4nlbu54e	272	18	for	for	IN
cord-350019-4nlbu54e	272	19	interrogating	interrogate	VBG
cord-350019-4nlbu54e	272	20	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	272	21	biology	biology	NN
cord-350019-4nlbu54e	272	22	.	.	.
cord-350019-4nlbu54e	273	1	An	an	DT
cord-350019-4nlbu54e	273	2	alternative	alternative	JJ
cord-350019-4nlbu54e	273	3	approach	approach	NN
cord-350019-4nlbu54e	273	4	to	to	IN
cord-350019-4nlbu54e	273	5	gene	gene	NN
cord-350019-4nlbu54e	273	6	ablation	ablation	NN
cord-350019-4nlbu54e	273	7	is	be	VBZ
cord-350019-4nlbu54e	273	8	overexpression	overexpression	NN
cord-350019-4nlbu54e	273	9	,	,	,
cord-350019-4nlbu54e	273	10	gain	gain	NN
cord-350019-4nlbu54e	273	11	-	-	HYPH
cord-350019-4nlbu54e	273	12	offunction	offunction	NN
cord-350019-4nlbu54e	273	13	.	.	.
cord-350019-4nlbu54e	274	1	Plasmid	plasmid	NN
cord-350019-4nlbu54e	274	2	-	-	HYPH
cord-350019-4nlbu54e	274	3	based	base	VBN
cord-350019-4nlbu54e	274	4	overexpression	overexpression	NN
cord-350019-4nlbu54e	274	5	systems	system	NNS
cord-350019-4nlbu54e	274	6	have	have	VBP
cord-350019-4nlbu54e	274	7	been	be	VBN
cord-350019-4nlbu54e	274	8	used	use	VBN
cord-350019-4nlbu54e	274	9	for	for	IN
cord-350019-4nlbu54e	274	10	decades	decade	NNS
cord-350019-4nlbu54e	274	11	to	to	TO
cord-350019-4nlbu54e	274	12	overexpress	overexpress	VB
cord-350019-4nlbu54e	274	13	specific	specific	JJ
cord-350019-4nlbu54e	274	14	coding	code	VBG
cord-350019-4nlbu54e	274	15	genes	gene	NNS
cord-350019-4nlbu54e	274	16	[	[	-LRB-
cord-350019-4nlbu54e	274	17	178	178	CD
cord-350019-4nlbu54e	274	18	]	]	-RRB-
cord-350019-4nlbu54e	274	19	.	.	.
cord-350019-4nlbu54e	275	1	Plasmid	plasmid	NN
cord-350019-4nlbu54e	275	2	-	-	HYPH
cord-350019-4nlbu54e	275	3	based	base	VBN
cord-350019-4nlbu54e	275	4	over	over	IN
cord-350019-4nlbu54e	275	5	-	-	HYPH
cord-350019-4nlbu54e	275	6	expression	expression	NN
cord-350019-4nlbu54e	275	7	of	of	IN
cord-350019-4nlbu54e	275	8	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	275	9	is	be	VBZ
cord-350019-4nlbu54e	275	10	possible	possible	JJ
cord-350019-4nlbu54e	275	11	but	but	CC
cord-350019-4nlbu54e	275	12	is	be	VBZ
cord-350019-4nlbu54e	275	13	limited	limit	VBN
cord-350019-4nlbu54e	275	14	by	by	IN
cord-350019-4nlbu54e	275	15	the	the	DT
cord-350019-4nlbu54e	275	16	size	size	NN
cord-350019-4nlbu54e	275	17	(	(	-LRB-
cord-350019-4nlbu54e	275	18	max	max	NNP
cord-350019-4nlbu54e	275	19	size	size	NN
cord-350019-4nlbu54e	275	20	:	:	:
cord-350019-4nlbu54e	275	21	6	6	CD
cord-350019-4nlbu54e	275	22	-	-	SYM
cord-350019-4nlbu54e	275	23	8	8	CD
cord-350019-4nlbu54e	275	24	kb	kb	NNP
cord-350019-4nlbu54e	275	25	)	)	-RRB-
cord-350019-4nlbu54e	275	26	of	of	IN
cord-350019-4nlbu54e	275	27	the	the	DT
cord-350019-4nlbu54e	275	28	specific	specific	JJ
cord-350019-4nlbu54e	275	29	lncRNA	lncrna	NN
cord-350019-4nlbu54e	275	30	(	(	-LRB-
cord-350019-4nlbu54e	275	31	unpublished	unpublished	JJ
cord-350019-4nlbu54e	275	32	observations	observation	NNS
cord-350019-4nlbu54e	275	33	)	)	-RRB-
cord-350019-4nlbu54e	275	34	.	.	.
cord-350019-4nlbu54e	276	1	However	however	RB
cord-350019-4nlbu54e	276	2	,	,	,
cord-350019-4nlbu54e	276	3	because	because	IN
cord-350019-4nlbu54e	276	4	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	276	5	can	can	MD
cord-350019-4nlbu54e	276	6	function	function	VB
cord-350019-4nlbu54e	276	7	in	in	IN
cord-350019-4nlbu54e	276	8	cis	cis	NNP
cord-350019-4nlbu54e	276	9	,	,	,
cord-350019-4nlbu54e	276	10	it	-PRON-	PRP
cord-350019-4nlbu54e	276	11	's	be	VBZ
cord-350019-4nlbu54e	276	12	important	important	JJ
cord-350019-4nlbu54e	276	13	that	that	IN
cord-350019-4nlbu54e	276	14	there	there	EX
cord-350019-4nlbu54e	276	15	is	be	VBZ
cord-350019-4nlbu54e	276	16	the	the	DT
cord-350019-4nlbu54e	276	17	significant	significant	JJ
cord-350019-4nlbu54e	276	18	mechanistic	mechanistic	JJ
cord-350019-4nlbu54e	276	19	characterization	characterization	NN
cord-350019-4nlbu54e	276	20	of	of	IN
cord-350019-4nlbu54e	276	21	the	the	DT
cord-350019-4nlbu54e	276	22	candidate	candidate	NN
cord-350019-4nlbu54e	276	23	lncRNA	lncRNA	VBZ
cord-350019-4nlbu54e	276	24	to	to	TO
cord-350019-4nlbu54e	276	25	justify	justify	VB
cord-350019-4nlbu54e	276	26	its	-PRON-	PRP$
cord-350019-4nlbu54e	276	27	cloning	cloning	NN
cord-350019-4nlbu54e	276	28	into	into	IN
cord-350019-4nlbu54e	276	29	a	a	DT
cord-350019-4nlbu54e	276	30	plasmid	plasmid	NN
cord-350019-4nlbu54e	276	31	.	.	.
cord-350019-4nlbu54e	277	1	The	the	DT
cord-350019-4nlbu54e	277	2	same	same	JJ
cord-350019-4nlbu54e	277	3	catalytically	catalytically	RB
cord-350019-4nlbu54e	277	4	inactivated	inactivate	VBN
cord-350019-4nlbu54e	277	5	Cas9	Cas9	NNP
cord-350019-4nlbu54e	277	6	has	have	VBZ
cord-350019-4nlbu54e	277	7	also	also	RB
cord-350019-4nlbu54e	277	8	been	be	VBN
cord-350019-4nlbu54e	277	9	fused	fuse	VBN
cord-350019-4nlbu54e	277	10	to	to	IN
cord-350019-4nlbu54e	277	11	a	a	DT
cord-350019-4nlbu54e	277	12	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	277	13	activation	activation	NN
cord-350019-4nlbu54e	277	14	domain	domain	NN
cord-350019-4nlbu54e	277	15	,	,	,
cord-350019-4nlbu54e	277	16	for	for	IN
cord-350019-4nlbu54e	277	17	example	example	NN
cord-350019-4nlbu54e	277	18	,	,	,
cord-350019-4nlbu54e	277	19	the	the	DT
cord-350019-4nlbu54e	277	20	VP16	VP16	NNP
cord-350019-4nlbu54e	277	21	,	,	,
cord-350019-4nlbu54e	277	22	a	a	DT
cord-350019-4nlbu54e	277	23	strong	strong	JJ
cord-350019-4nlbu54e	277	24	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	277	25	activator	activator	NN
cord-350019-4nlbu54e	277	26	derived	derive	VBN
cord-350019-4nlbu54e	277	27	from	from	IN
cord-350019-4nlbu54e	277	28	herpesviruses	herpesviruses	NNP
cord-350019-4nlbu54e	277	29	[	[	-LRB-
cord-350019-4nlbu54e	277	30	179	179	CD
cord-350019-4nlbu54e	277	31	,	,	,
cord-350019-4nlbu54e	277	32	180	180	CD
cord-350019-4nlbu54e	277	33	]	]	-RRB-
cord-350019-4nlbu54e	277	34	.	.	.
cord-350019-4nlbu54e	278	1	This	this	DT
cord-350019-4nlbu54e	278	2	strategy	strategy	NN
cord-350019-4nlbu54e	278	3	allows	allow	VBZ
cord-350019-4nlbu54e	278	4	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	278	5	-	-	HYPH
cord-350019-4nlbu54e	278	6	based	base	VBN
cord-350019-4nlbu54e	278	7	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	278	8	gene	gene	NN
cord-350019-4nlbu54e	278	9	activation	activation	NN
cord-350019-4nlbu54e	278	10	that	that	WDT
cord-350019-4nlbu54e	278	11	can	can	MD
cord-350019-4nlbu54e	278	12	be	be	VB
cord-350019-4nlbu54e	278	13	used	use	VBN
cord-350019-4nlbu54e	278	14	to	to	TO
cord-350019-4nlbu54e	278	15	study	study	VB
cord-350019-4nlbu54e	278	16	gain	gain	NN
cord-350019-4nlbu54e	278	17	-	-	HYPH
cord-350019-4nlbu54e	278	18	of	of	IN
cord-350019-4nlbu54e	278	19	-	-	HYPH
cord-350019-4nlbu54e	278	20	function	function	NN
cord-350019-4nlbu54e	278	21	phenotypes	phenotype	NNS
cord-350019-4nlbu54e	278	22	.	.	.
cord-350019-4nlbu54e	279	1	The	the	DT
cord-350019-4nlbu54e	279	2	Zhang	Zhang	NNP
cord-350019-4nlbu54e	279	3	group	group	NN
cord-350019-4nlbu54e	279	4	recently	recently	RB
cord-350019-4nlbu54e	279	5	performed	perform	VBD
cord-350019-4nlbu54e	279	6	a	a	DT
cord-350019-4nlbu54e	279	7	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	279	8	activation	activation	NN
cord-350019-4nlbu54e	279	9	screen	screen	NN
cord-350019-4nlbu54e	279	10	targeting	target	VBG
cord-350019-4nlbu54e	279	11	over	over	IN
cord-350019-4nlbu54e	279	12	10-thousand	10-thousand	CD
cord-350019-4nlbu54e	279	13	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	279	14	[	[	-LRB-
cord-350019-4nlbu54e	279	15	181	181	CD
cord-350019-4nlbu54e	279	16	]	]	-RRB-
cord-350019-4nlbu54e	279	17	.	.	.
cord-350019-4nlbu54e	280	1	They	-PRON-	PRP
cord-350019-4nlbu54e	280	2	identified	identify	VBD
cord-350019-4nlbu54e	280	3	11	11	CD
cord-350019-4nlbu54e	280	4	lncRNAs	lncrnas	VBP
cord-350019-4nlbu54e	280	5	that	that	IN
cord-350019-4nlbu54e	280	6	upon	upon	IN
cord-350019-4nlbu54e	280	7	activation	activation	NN
cord-350019-4nlbu54e	280	8	,	,	,
cord-350019-4nlbu54e	280	9	mediated	mediate	VBN
cord-350019-4nlbu54e	280	10	BRAF	BRAF	NNP
cord-350019-4nlbu54e	280	11	inhibitor	inhibitor	NN
cord-350019-4nlbu54e	280	12	resistance	resistance	NN
cord-350019-4nlbu54e	280	13	in	in	IN
cord-350019-4nlbu54e	280	14	melanoma	melanoma	NN
cord-350019-4nlbu54e	280	15	cells	cell	NNS
cord-350019-4nlbu54e	280	16	[	[	-LRB-
cord-350019-4nlbu54e	280	17	181	181	CD
cord-350019-4nlbu54e	280	18	]	]	-RRB-
cord-350019-4nlbu54e	280	19	.	.	.
cord-350019-4nlbu54e	281	1	One	one	CD
cord-350019-4nlbu54e	281	2	of	of	IN
cord-350019-4nlbu54e	281	3	the	the	DT
cord-350019-4nlbu54e	281	4	advantages	advantage	NNS
cord-350019-4nlbu54e	281	5	of	of	IN
cord-350019-4nlbu54e	281	6	using	use	VBG
cord-350019-4nlbu54e	281	7	a	a	DT
cord-350019-4nlbu54e	281	8	CRISPRa	CRISPRa	NNP
cord-350019-4nlbu54e	281	9	library	library	NN
cord-350019-4nlbu54e	281	10	is	be	VBZ
cord-350019-4nlbu54e	281	11	that	that	IN
cord-350019-4nlbu54e	281	12	the	the	DT
cord-350019-4nlbu54e	281	13	same	same	JJ
cord-350019-4nlbu54e	281	14	library	library	NN
cord-350019-4nlbu54e	281	15	can	can	MD
cord-350019-4nlbu54e	281	16	be	be	VB
cord-350019-4nlbu54e	281	17	used	use	VBN
cord-350019-4nlbu54e	281	18	across	across	IN
cord-350019-4nlbu54e	281	19	different	different	JJ
cord-350019-4nlbu54e	281	20	cell	cell	NN
cord-350019-4nlbu54e	281	21	types	type	NNS
cord-350019-4nlbu54e	281	22	,	,	,
cord-350019-4nlbu54e	281	23	which	which	WDT
cord-350019-4nlbu54e	281	24	makes	make	VBZ
cord-350019-4nlbu54e	281	25	it	-PRON-	PRP
cord-350019-4nlbu54e	281	26	more	more	RBR
cord-350019-4nlbu54e	281	27	cost	cost	NN
cord-350019-4nlbu54e	281	28	effective	effective	JJ
cord-350019-4nlbu54e	281	29	.	.	.
cord-350019-4nlbu54e	282	1	Nevertheless	nevertheless	RB
cord-350019-4nlbu54e	282	2	,	,	,
cord-350019-4nlbu54e	282	3	several	several	JJ
cord-350019-4nlbu54e	282	4	caveats	caveat	NNS
cord-350019-4nlbu54e	282	5	to	to	IN
cord-350019-4nlbu54e	282	6	the	the	DT
cord-350019-4nlbu54e	282	7	CRISPRa	CRISPRa	NNS
cord-350019-4nlbu54e	282	8	system	system	NN
cord-350019-4nlbu54e	282	9	,	,	,
cord-350019-4nlbu54e	282	10	include	include	VBP
cord-350019-4nlbu54e	282	11	the	the	DT
cord-350019-4nlbu54e	282	12	possibility	possibility	NN
cord-350019-4nlbu54e	282	13	that	that	IN
cord-350019-4nlbu54e	282	14	high	high	JJ
cord-350019-4nlbu54e	282	15	expression	expression	NN
cord-350019-4nlbu54e	282	16	of	of	IN
cord-350019-4nlbu54e	282	17	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	282	18	may	may	MD
cord-350019-4nlbu54e	282	19	create	create	VB
cord-350019-4nlbu54e	282	20	non	non	JJ
cord-350019-4nlbu54e	282	21	-	-	JJ
cord-350019-4nlbu54e	282	22	physiological	physiological	JJ
cord-350019-4nlbu54e	282	23	conditions	condition	NNS
cord-350019-4nlbu54e	282	24	leading	lead	VBG
cord-350019-4nlbu54e	282	25	to	to	IN
cord-350019-4nlbu54e	282	26	incorrect	incorrect	JJ
cord-350019-4nlbu54e	282	27	conclusions	conclusion	NNS
cord-350019-4nlbu54e	282	28	of	of	IN
cord-350019-4nlbu54e	282	29	specific	specific	JJ
cord-350019-4nlbu54e	282	30	biology	biology	NN
cord-350019-4nlbu54e	282	31	.	.	.
cord-350019-4nlbu54e	283	1	LncRNAs	lncrna	NNS
cord-350019-4nlbu54e	283	2	have	have	VBP
cord-350019-4nlbu54e	283	3	been	be	VBN
cord-350019-4nlbu54e	283	4	shown	show	VBN
cord-350019-4nlbu54e	283	5	to	to	TO
cord-350019-4nlbu54e	283	6	mediate	mediate	VB
cord-350019-4nlbu54e	283	7	functions	function	NNS
cord-350019-4nlbu54e	283	8	via	via	IN
cord-350019-4nlbu54e	283	9	binding	bind	VBG
cord-350019-4nlbu54e	283	10	to	to	IN
cord-350019-4nlbu54e	283	11	specific	specific	JJ
cord-350019-4nlbu54e	283	12	proteins	protein	NNS
cord-350019-4nlbu54e	283	13	.	.	.
cord-350019-4nlbu54e	284	1	Hence	hence	RB
cord-350019-4nlbu54e	284	2	over	over	IN
cord-350019-4nlbu54e	284	3	-	-	HYPH
cord-350019-4nlbu54e	284	4	expression	expression	NN
cord-350019-4nlbu54e	284	5	of	of	IN
cord-350019-4nlbu54e	284	6	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	284	7	,	,	,
cord-350019-4nlbu54e	284	8	without	without	IN
cord-350019-4nlbu54e	284	9	its	-PRON-	PRP$
cord-350019-4nlbu54e	284	10	protein	protein	NN
cord-350019-4nlbu54e	284	11	partner	partner	NN
cord-350019-4nlbu54e	284	12	,	,	,
cord-350019-4nlbu54e	284	13	may	may	MD
cord-350019-4nlbu54e	284	14	result	result	VB
cord-350019-4nlbu54e	284	15	in	in	IN
cord-350019-4nlbu54e	284	16	the	the	DT
cord-350019-4nlbu54e	284	17	inability	inability	NN
cord-350019-4nlbu54e	284	18	to	to	TO
cord-350019-4nlbu54e	284	19	identify	identify	VB
cord-350019-4nlbu54e	284	20	important	important	JJ
cord-350019-4nlbu54e	284	21	biology	biology	NN
cord-350019-4nlbu54e	284	22	.	.	.
cord-350019-4nlbu54e	285	1	In	in	IN
cord-350019-4nlbu54e	285	2	conclusion	conclusion	NN
cord-350019-4nlbu54e	285	3	,	,	,
cord-350019-4nlbu54e	285	4	it	-PRON-	PRP
cord-350019-4nlbu54e	285	5	's	be	VBZ
cord-350019-4nlbu54e	285	6	important	important	JJ
cord-350019-4nlbu54e	285	7	to	to	TO
cord-350019-4nlbu54e	285	8	understand	understand	VB
cord-350019-4nlbu54e	285	9	the	the	DT
cord-350019-4nlbu54e	285	10	advantages	advantage	NNS
cord-350019-4nlbu54e	285	11	and	and	CC
cord-350019-4nlbu54e	285	12	disadvantages	disadvantage	NNS
cord-350019-4nlbu54e	285	13	of	of	IN
cord-350019-4nlbu54e	285	14	the	the	DT
cord-350019-4nlbu54e	285	15	loss	loss	NN
cord-350019-4nlbu54e	285	16	-	-	:
cord-350019-4nlbu54e	285	17	or	or	CC
cord-350019-4nlbu54e	285	18	gain	gain	NN
cord-350019-4nlbu54e	285	19	-	-	HYPH
cord-350019-4nlbu54e	285	20	of	of	IN
cord-350019-4nlbu54e	285	21	-	-	HYPH
cord-350019-4nlbu54e	285	22	function	function	NN
cord-350019-4nlbu54e	285	23	methods	method	NNS
cord-350019-4nlbu54e	285	24	used	use	VBN
cord-350019-4nlbu54e	285	25	to	to	TO
cord-350019-4nlbu54e	285	26	modulate	modulate	VB
cord-350019-4nlbu54e	285	27	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	285	28	expression	expression	NN
cord-350019-4nlbu54e	285	29	.	.	.
cord-350019-4nlbu54e	286	1	All	all	DT
cord-350019-4nlbu54e	286	2	methods	method	NNS
cord-350019-4nlbu54e	286	3	have	have	VBP
cord-350019-4nlbu54e	286	4	their	-PRON-	PRP$
cord-350019-4nlbu54e	286	5	caveats	caveat	NNS
cord-350019-4nlbu54e	286	6	,	,	,
cord-350019-4nlbu54e	286	7	and	and	CC
cord-350019-4nlbu54e	286	8	these	these	DT
cord-350019-4nlbu54e	286	9	are	be	VBP
cord-350019-4nlbu54e	286	10	important	important	JJ
cord-350019-4nlbu54e	286	11	to	to	TO
cord-350019-4nlbu54e	286	12	consider	consider	VB
cord-350019-4nlbu54e	286	13	when	when	WRB
cord-350019-4nlbu54e	286	14	deciding	decide	VBG
cord-350019-4nlbu54e	286	15	which	which	WDT
cord-350019-4nlbu54e	286	16	method	method	NN
cord-350019-4nlbu54e	286	17	to	to	TO
cord-350019-4nlbu54e	286	18	use	use	VB
cord-350019-4nlbu54e	286	19	.	.	.
cord-350019-4nlbu54e	287	1	LncRNAs	LncRNAs	NNP
cord-350019-4nlbu54e	287	2	can	can	MD
cord-350019-4nlbu54e	287	3	span	span	VB
cord-350019-4nlbu54e	287	4	large	large	JJ
cord-350019-4nlbu54e	287	5	stretches	stretch	NNS
cord-350019-4nlbu54e	287	6	of	of	IN
cord-350019-4nlbu54e	287	7	DNA	dna	NN
cord-350019-4nlbu54e	287	8	sequence	sequence	NN
cord-350019-4nlbu54e	287	9	and	and	CC
cord-350019-4nlbu54e	287	10	can	can	MD
cord-350019-4nlbu54e	287	11	contain	contain	VB
cord-350019-4nlbu54e	287	12	important	important	JJ
cord-350019-4nlbu54e	287	13	regulatory	regulatory	JJ
cord-350019-4nlbu54e	287	14	regions	region	NNS
cord-350019-4nlbu54e	287	15	,	,	,
cord-350019-4nlbu54e	287	16	such	such	JJ
cord-350019-4nlbu54e	287	17	as	as	IN
cord-350019-4nlbu54e	287	18	enhancers	enhancer	NNS
cord-350019-4nlbu54e	287	19	,	,	,
cord-350019-4nlbu54e	287	20	that	that	WDT
cord-350019-4nlbu54e	287	21	are	be	VBP
cord-350019-4nlbu54e	287	22	functionally	functionally	RB
cord-350019-4nlbu54e	287	23	independent	independent	JJ
cord-350019-4nlbu54e	287	24	of	of	IN
cord-350019-4nlbu54e	287	25	the	the	DT
cord-350019-4nlbu54e	287	26	lncRNA	lncrna	NN
cord-350019-4nlbu54e	287	27	product	product	NN
cord-350019-4nlbu54e	287	28	[	[	-LRB-
cord-350019-4nlbu54e	287	29	182	182	CD
cord-350019-4nlbu54e	287	30	]	]	-RRB-
cord-350019-4nlbu54e	287	31	.	.	.
cord-350019-4nlbu54e	288	1	LncRNA	lncrna	NN
cord-350019-4nlbu54e	288	2	promoters	promoter	NNS
cord-350019-4nlbu54e	288	3	have	have	VBP
cord-350019-4nlbu54e	288	4	been	be	VBN
cord-350019-4nlbu54e	288	5	proposed	propose	VBN
cord-350019-4nlbu54e	288	6	to	to	TO
cord-350019-4nlbu54e	288	7	also	also	RB
cord-350019-4nlbu54e	288	8	function	function	VB
cord-350019-4nlbu54e	288	9	as	as	IN
cord-350019-4nlbu54e	288	10	enhancers	enhancer	NNS
cord-350019-4nlbu54e	288	11	,	,	,
cord-350019-4nlbu54e	288	12	promoting	promote	VBG
cord-350019-4nlbu54e	288	13	the	the	DT
cord-350019-4nlbu54e	288	14	recruitment	recruitment	NN
cord-350019-4nlbu54e	288	15	of	of	IN
cord-350019-4nlbu54e	288	16	transcriptional	transcriptional	NN
cord-350019-4nlbu54e	288	17	-	-	HYPH
cord-350019-4nlbu54e	288	18	activating	activate	VBG
cord-350019-4nlbu54e	288	19	factors	factor	NNS
cord-350019-4nlbu54e	288	20	that	that	WDT
cord-350019-4nlbu54e	288	21	can	can	MD
cord-350019-4nlbu54e	288	22	affect	affect	VB
cord-350019-4nlbu54e	288	23	the	the	DT
cord-350019-4nlbu54e	288	24	local	local	JJ
cord-350019-4nlbu54e	288	25	nucleosome	nucleosome	NN
cord-350019-4nlbu54e	288	26	environment	environment	NN
cord-350019-4nlbu54e	288	27	and	and	CC
cord-350019-4nlbu54e	288	28	ultimately	ultimately	RB
cord-350019-4nlbu54e	288	29	the	the	DT
cord-350019-4nlbu54e	288	30	expression	expression	NN
cord-350019-4nlbu54e	288	31	of	of	IN
cord-350019-4nlbu54e	288	32	neighboring	neighboring	NN
cord-350019-4nlbu54e	288	33	genes	gene	NNS
cord-350019-4nlbu54e	288	34	[	[	-LRB-
cord-350019-4nlbu54e	288	35	118	118	CD
cord-350019-4nlbu54e	288	36	,	,	,
cord-350019-4nlbu54e	288	37	183	183	CD
cord-350019-4nlbu54e	288	38	,	,	,
cord-350019-4nlbu54e	288	39	184	184	CD
cord-350019-4nlbu54e	288	40	]	]	-RRB-
cord-350019-4nlbu54e	288	41	.	.	.
cord-350019-4nlbu54e	289	1	Nevertheless	nevertheless	RB
cord-350019-4nlbu54e	289	2	,	,	,
cord-350019-4nlbu54e	289	3	in	in	IN
cord-350019-4nlbu54e	289	4	vivo	vivo	NN
cord-350019-4nlbu54e	289	5	assessment	assessment	NN
cord-350019-4nlbu54e	289	6	of	of	IN
cord-350019-4nlbu54e	289	7	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	289	8	function	function	NN
cord-350019-4nlbu54e	289	9	has	have	VBZ
cord-350019-4nlbu54e	289	10	predominantly	predominantly	RB
cord-350019-4nlbu54e	289	11	relied	rely	VBN
cord-350019-4nlbu54e	289	12	on	on	IN
cord-350019-4nlbu54e	289	13	assessing	assess	VBG
cord-350019-4nlbu54e	289	14	the	the	DT
cord-350019-4nlbu54e	289	15	consequence	consequence	NN
cord-350019-4nlbu54e	289	16	of	of	IN
cord-350019-4nlbu54e	289	17	deleting	delete	VBG
cord-350019-4nlbu54e	289	18	entire	entire	JJ
cord-350019-4nlbu54e	289	19	lncRNA	lncrna	NN
cord-350019-4nlbu54e	289	20	loci	locus	NNS
cord-350019-4nlbu54e	289	21	[	[	-LRB-
cord-350019-4nlbu54e	289	22	171	171	CD
cord-350019-4nlbu54e	289	23	,	,	,
cord-350019-4nlbu54e	289	24	185	185	CD
cord-350019-4nlbu54e	289	25	]	]	-RRB-
cord-350019-4nlbu54e	289	26	.	.	.
cord-350019-4nlbu54e	290	1	Numerous	numerous	JJ
cord-350019-4nlbu54e	290	2	studies	study	NNS
cord-350019-4nlbu54e	290	3	involving	involve	VBG
cord-350019-4nlbu54e	290	4	deletion	deletion	NN
cord-350019-4nlbu54e	290	5	of	of	IN
cord-350019-4nlbu54e	290	6	lncRNA	lncrna	NN
cord-350019-4nlbu54e	290	7	loci	locus	NNS
cord-350019-4nlbu54e	290	8	have	have	VBP
cord-350019-4nlbu54e	290	9	been	be	VBN
cord-350019-4nlbu54e	290	10	unable	unable	JJ
cord-350019-4nlbu54e	290	11	to	to	TO
cord-350019-4nlbu54e	290	12	rescue	rescue	VB
cord-350019-4nlbu54e	290	13	the	the	DT
cord-350019-4nlbu54e	290	14	deletion	deletion	NN
cord-350019-4nlbu54e	290	15	phenotype	phenotype	NN
cord-350019-4nlbu54e	290	16	using	use	VBG
cord-350019-4nlbu54e	290	17	a	a	DT
cord-350019-4nlbu54e	290	18	transgene	transgene	NN
cord-350019-4nlbu54e	290	19	approach	approach	NN
cord-350019-4nlbu54e	290	20	,	,	,
cord-350019-4nlbu54e	290	21	making	make	VBG
cord-350019-4nlbu54e	290	22	it	-PRON-	PRP
cord-350019-4nlbu54e	290	23	difficult	difficult	JJ
cord-350019-4nlbu54e	290	24	to	to	TO
cord-350019-4nlbu54e	290	25	attribute	attribute	VB
cord-350019-4nlbu54e	290	26	the	the	DT
cord-350019-4nlbu54e	290	27	phenotype	phenotype	NN
cord-350019-4nlbu54e	290	28	to	to	IN
cord-350019-4nlbu54e	290	29	the	the	DT
cord-350019-4nlbu54e	290	30	lncRNA	lncrna	NN
cord-350019-4nlbu54e	290	31	product	product	NN
cord-350019-4nlbu54e	290	32	itself	-PRON-	PRP
cord-350019-4nlbu54e	290	33	[	[	-LRB-
cord-350019-4nlbu54e	290	34	186	186	CD
cord-350019-4nlbu54e	290	35	,	,	,
cord-350019-4nlbu54e	290	36	187	187	CD
cord-350019-4nlbu54e	290	37	]	]	-RRB-
cord-350019-4nlbu54e	290	38	.	.	.
cord-350019-4nlbu54e	291	1	While	while	IN
cord-350019-4nlbu54e	291	2	deleting	delete	VBG
cord-350019-4nlbu54e	291	3	the	the	DT
cord-350019-4nlbu54e	291	4	entire	entire	JJ
cord-350019-4nlbu54e	291	5	lncRNA	lncrna	NN
cord-350019-4nlbu54e	291	6	is	be	VBZ
cord-350019-4nlbu54e	291	7	a	a	DT
cord-350019-4nlbu54e	291	8	useful	useful	JJ
cord-350019-4nlbu54e	291	9	first	first	JJ
cord-350019-4nlbu54e	291	10	step	step	NN
cord-350019-4nlbu54e	291	11	to	to	TO
cord-350019-4nlbu54e	291	12	establish	establish	VB
cord-350019-4nlbu54e	291	13	a	a	DT
cord-350019-4nlbu54e	291	14	phenotype	phenotype	NN
cord-350019-4nlbu54e	291	15	,	,	,
cord-350019-4nlbu54e	291	16	this	this	DT
cord-350019-4nlbu54e	291	17	approach	approach	NN
cord-350019-4nlbu54e	291	18	can	can	MD
cord-350019-4nlbu54e	291	19	make	make	VB
cord-350019-4nlbu54e	291	20	it	-PRON-	PRP
cord-350019-4nlbu54e	291	21	difficult	difficult	JJ
cord-350019-4nlbu54e	291	22	to	to	TO
cord-350019-4nlbu54e	291	23	identify	identify	VB
cord-350019-4nlbu54e	291	24	which	which	WDT
cord-350019-4nlbu54e	291	25	component	component	NN
cord-350019-4nlbu54e	291	26	of	of	IN
cord-350019-4nlbu54e	291	27	the	the	DT
cord-350019-4nlbu54e	291	28	lncRNA	lncrna	NN
cord-350019-4nlbu54e	291	29	is	be	VBZ
cord-350019-4nlbu54e	291	30	important	important	JJ
cord-350019-4nlbu54e	291	31	for	for	IN
cord-350019-4nlbu54e	291	32	the	the	DT
cord-350019-4nlbu54e	291	33	observed	observed	JJ
cord-350019-4nlbu54e	291	34	phenotype	phenotype	NN
cord-350019-4nlbu54e	291	35	[	[	-LRB-
cord-350019-4nlbu54e	291	36	171	171	CD
cord-350019-4nlbu54e	291	37	,	,	,
cord-350019-4nlbu54e	291	38	185	185	CD
cord-350019-4nlbu54e	291	39	,	,	,
cord-350019-4nlbu54e	291	40	[	[	-LRB-
cord-350019-4nlbu54e	291	41	188	188	CD
cord-350019-4nlbu54e	291	42	]	]	-RRB-
cord-350019-4nlbu54e	291	43	[	[	-LRB-
cord-350019-4nlbu54e	291	44	189	189	CD
cord-350019-4nlbu54e	291	45	]	]	-RRB-
cord-350019-4nlbu54e	291	46	[	[	-LRB-
cord-350019-4nlbu54e	291	47	190	190	CD
cord-350019-4nlbu54e	291	48	]	]	-RRB-
cord-350019-4nlbu54e	291	49	.	.	.
cord-350019-4nlbu54e	292	1	There	there	EX
cord-350019-4nlbu54e	292	2	are	be	VBP
cord-350019-4nlbu54e	292	3	many	many	JJ
cord-350019-4nlbu54e	292	4	approaches	approach	NNS
cord-350019-4nlbu54e	292	5	to	to	IN
cord-350019-4nlbu54e	292	6	generating	generate	VBG
cord-350019-4nlbu54e	292	7	a	a	DT
cord-350019-4nlbu54e	292	8	lncRNA	lncrna	NN
cord-350019-4nlbu54e	292	9	knockout/	knockout/	CD
cord-350019-4nlbu54e	292	10	knockdown	knockdown	NN
cord-350019-4nlbu54e	292	11	mouse	mouse	NN
cord-350019-4nlbu54e	292	12	.	.	.
cord-350019-4nlbu54e	293	1	For	for	IN
cord-350019-4nlbu54e	293	2	instance	instance	NN
cord-350019-4nlbu54e	293	3	,	,	,
cord-350019-4nlbu54e	293	4	the	the	DT
cord-350019-4nlbu54e	293	5	complete	complete	JJ
cord-350019-4nlbu54e	293	6	knockout	knockout	NN
cord-350019-4nlbu54e	293	7	is	be	VBZ
cord-350019-4nlbu54e	293	8	the	the	DT
cord-350019-4nlbu54e	293	9	easiest	easy	JJS
cord-350019-4nlbu54e	293	10	first	first	JJ
cord-350019-4nlbu54e	293	11	step	step	NN
cord-350019-4nlbu54e	293	12	to	to	TO
cord-350019-4nlbu54e	293	13	take	take	VB
cord-350019-4nlbu54e	293	14	,	,	,
cord-350019-4nlbu54e	293	15	which	which	WDT
cord-350019-4nlbu54e	293	16	can	can	MD
cord-350019-4nlbu54e	293	17	be	be	VB
cord-350019-4nlbu54e	293	18	designed	design	VBN
cord-350019-4nlbu54e	293	19	to	to	TO
cord-350019-4nlbu54e	293	20	remove	remove	VB
cord-350019-4nlbu54e	293	21	the	the	DT
cord-350019-4nlbu54e	293	22	entire	entire	JJ
cord-350019-4nlbu54e	293	23	gene	gene	NN
cord-350019-4nlbu54e	293	24	.	.	.
cord-350019-4nlbu54e	294	1	After	after	IN
cord-350019-4nlbu54e	294	2	this	this	DT
cord-350019-4nlbu54e	294	3	approach	approach	NN
cord-350019-4nlbu54e	294	4	,	,	,
cord-350019-4nlbu54e	294	5	one	one	PRP
cord-350019-4nlbu54e	294	6	can	can	MD
cord-350019-4nlbu54e	294	7	use	use	VB
cord-350019-4nlbu54e	294	8	a	a	DT
cord-350019-4nlbu54e	294	9	more	more	RBR
cord-350019-4nlbu54e	294	10	fine	fine	RB
cord-350019-4nlbu54e	294	11	-	-	HYPH
cord-350019-4nlbu54e	294	12	tuned	tune	VBN
cord-350019-4nlbu54e	294	13	approach	approach	NN
cord-350019-4nlbu54e	294	14	to	to	TO
cord-350019-4nlbu54e	294	15	reveal	reveal	VB
cord-350019-4nlbu54e	294	16	exactly	exactly	RB
cord-350019-4nlbu54e	294	17	how	how	WRB
cord-350019-4nlbu54e	294	18	the	the	DT
cord-350019-4nlbu54e	294	19	gene	gene	NN
cord-350019-4nlbu54e	294	20	is	be	VBZ
cord-350019-4nlbu54e	294	21	working	work	VBG
cord-350019-4nlbu54e	294	22	,	,	,
cord-350019-4nlbu54e	294	23	including	include	VBG
cord-350019-4nlbu54e	294	24	deleting	delete	VBG
cord-350019-4nlbu54e	294	25	specific	specific	JJ
cord-350019-4nlbu54e	294	26	regions	region	NNS
cord-350019-4nlbu54e	294	27	of	of	IN
cord-350019-4nlbu54e	294	28	the	the	DT
cord-350019-4nlbu54e	294	29	gene	gene	NN
cord-350019-4nlbu54e	294	30	or	or	CC
cord-350019-4nlbu54e	294	31	inserting	insert	VBG
cord-350019-4nlbu54e	294	32	a	a	DT
cord-350019-4nlbu54e	294	33	poly	poly	JJ
cord-350019-4nlbu54e	294	34	-	-	HYPH
cord-350019-4nlbu54e	294	35	adenylation	adenylation	NN
cord-350019-4nlbu54e	294	36	cassette	cassette	NN
cord-350019-4nlbu54e	294	37	before	before	IN
cord-350019-4nlbu54e	294	38	the	the	DT
cord-350019-4nlbu54e	294	39	exon1	exon1	NN
cord-350019-4nlbu54e	294	40	of	of	IN
cord-350019-4nlbu54e	294	41	the	the	DT
cord-350019-4nlbu54e	294	42	gene	gene	NN
cord-350019-4nlbu54e	294	43	.	.	.
cord-350019-4nlbu54e	295	1	A	a	DT
cord-350019-4nlbu54e	295	2	well	well	RB
cord-350019-4nlbu54e	295	3	-	-	HYPH
cord-350019-4nlbu54e	295	4	documented	document	VBN
cord-350019-4nlbu54e	295	5	example	example	NN
cord-350019-4nlbu54e	295	6	of	of	IN
cord-350019-4nlbu54e	295	7	this	this	DT
cord-350019-4nlbu54e	295	8	phenomena	phenomena	NN
cord-350019-4nlbu54e	295	9	is	be	VBZ
cord-350019-4nlbu54e	295	10	Fendrr	Fendrr	NNP
cord-350019-4nlbu54e	295	11	,	,	,
cord-350019-4nlbu54e	295	12	which	which	WDT
cord-350019-4nlbu54e	295	13	was	be	VBD
cord-350019-4nlbu54e	295	14	shown	show	VBN
cord-350019-4nlbu54e	295	15	to	to	TO
cord-350019-4nlbu54e	295	16	have	have	VB
cord-350019-4nlbu54e	295	17	a	a	DT
cord-350019-4nlbu54e	295	18	lethal	lethal	JJ
cord-350019-4nlbu54e	295	19	phenotype	phenotype	NN
cord-350019-4nlbu54e	295	20	in	in	IN
cord-350019-4nlbu54e	295	21	two	two	CD
cord-350019-4nlbu54e	295	22	independent	independent	JJ
cord-350019-4nlbu54e	295	23	studies	study	NNS
cord-350019-4nlbu54e	295	24	,	,	,
cord-350019-4nlbu54e	295	25	but	but	CC
cord-350019-4nlbu54e	295	26	the	the	DT
cord-350019-4nlbu54e	295	27	importance	importance	NN
cord-350019-4nlbu54e	295	28	of	of	IN
cord-350019-4nlbu54e	295	29	the	the	DT
cord-350019-4nlbu54e	295	30	lncRNA	lncrna	NN
cord-350019-4nlbu54e	295	31	in	in	IN
cord-350019-4nlbu54e	295	32	development	development	NN
cord-350019-4nlbu54e	295	33	differed	differ	VBD
cord-350019-4nlbu54e	295	34	due	due	JJ
cord-350019-4nlbu54e	295	35	to	to	IN
cord-350019-4nlbu54e	295	36	the	the	DT
cord-350019-4nlbu54e	295	37	mouse	mouse	NN
cord-350019-4nlbu54e	295	38	ablation	ablation	NN
cord-350019-4nlbu54e	295	39	strategy	strategy	NN
cord-350019-4nlbu54e	295	40	.	.	.
cord-350019-4nlbu54e	296	1	One	one	CD
cord-350019-4nlbu54e	296	2	in	in	IN
cord-350019-4nlbu54e	296	3	vivo	vivo	NN
cord-350019-4nlbu54e	296	4	study	study	NN
cord-350019-4nlbu54e	296	5	generated	generate	VBD
cord-350019-4nlbu54e	296	6	a	a	DT
cord-350019-4nlbu54e	296	7	knockout	knockout	NN
cord-350019-4nlbu54e	296	8	mouse	mouse	NN
cord-350019-4nlbu54e	296	9	by	by	IN
cord-350019-4nlbu54e	296	10	removing	remove	VBG
cord-350019-4nlbu54e	296	11	the	the	DT
cord-350019-4nlbu54e	296	12	genomic	genomic	JJ
cord-350019-4nlbu54e	296	13	loci	locus	NNS
cord-350019-4nlbu54e	296	14	completely	completely	RB
cord-350019-4nlbu54e	296	15	and	and	CC
cord-350019-4nlbu54e	296	16	replacing	replace	VBG
cord-350019-4nlbu54e	296	17	it	-PRON-	PRP
cord-350019-4nlbu54e	296	18	with	with	IN
cord-350019-4nlbu54e	296	19	LacZ	LacZ	NNP
cord-350019-4nlbu54e	296	20	while	while	IN
cord-350019-4nlbu54e	296	21	leaving	leave	VBG
cord-350019-4nlbu54e	296	22	the	the	DT
cord-350019-4nlbu54e	296	23	native	native	JJ
cord-350019-4nlbu54e	296	24	promoter	promoter	NN
cord-350019-4nlbu54e	296	25	intact	intact	JJ
cord-350019-4nlbu54e	296	26	[	[	-LRB-
cord-350019-4nlbu54e	296	27	185	185	CD
cord-350019-4nlbu54e	296	28	]	]	-RRB-
cord-350019-4nlbu54e	296	29	.	.	.
cord-350019-4nlbu54e	297	1	This	this	DT
cord-350019-4nlbu54e	297	2	study	study	NN
cord-350019-4nlbu54e	297	3	identified	identify	VBD
cord-350019-4nlbu54e	297	4	Fendrr	Fendrr	NNP
cord-350019-4nlbu54e	297	5	as	as	IN
cord-350019-4nlbu54e	297	6	a	a	DT
cord-350019-4nlbu54e	297	7	key	key	JJ
cord-350019-4nlbu54e	297	8	regulator	regulator	NN
cord-350019-4nlbu54e	297	9	of	of	IN
cord-350019-4nlbu54e	297	10	lung	lung	NN
cord-350019-4nlbu54e	297	11	development	development	NN
cord-350019-4nlbu54e	297	12	and	and	CC
cord-350019-4nlbu54e	297	13	mesenchymal	mesenchymal	JJ
cord-350019-4nlbu54e	297	14	differentiation	differentiation	NN
cord-350019-4nlbu54e	297	15	.	.	.
cord-350019-4nlbu54e	298	1	However	however	RB
cord-350019-4nlbu54e	298	2	this	this	DT
cord-350019-4nlbu54e	298	3	study	study	NN
cord-350019-4nlbu54e	298	4	did	do	VBD
cord-350019-4nlbu54e	298	5	not	not	RB
cord-350019-4nlbu54e	298	6	attempt	attempt	VB
cord-350019-4nlbu54e	298	7	to	to	TO
cord-350019-4nlbu54e	298	8	rescue	rescue	VB
cord-350019-4nlbu54e	298	9	the	the	DT
cord-350019-4nlbu54e	298	10	ablated	ablate	VBN
cord-350019-4nlbu54e	298	11	Fendrr	Fendrr	NNP
cord-350019-4nlbu54e	298	12	allele	allele	NN
cord-350019-4nlbu54e	298	13	via	via	IN
cord-350019-4nlbu54e	298	14	a	a	DT
cord-350019-4nlbu54e	298	15	transgene	transgene	NN
cord-350019-4nlbu54e	298	16	[	[	-LRB-
cord-350019-4nlbu54e	298	17	185	185	CD
cord-350019-4nlbu54e	298	18	]	]	-RRB-
cord-350019-4nlbu54e	298	19	.	.	.
cord-350019-4nlbu54e	299	1	An	an	DT
cord-350019-4nlbu54e	299	2	additional	additional	JJ
cord-350019-4nlbu54e	299	3	group	group	NN
cord-350019-4nlbu54e	299	4	generated	generate	VBD
cord-350019-4nlbu54e	299	5	a	a	DT
cord-350019-4nlbu54e	299	6	Fendrr	Fendrr	NNP
cord-350019-4nlbu54e	299	7	knockdown	knockdown	NN
cord-350019-4nlbu54e	299	8	mouse	mouse	NN
cord-350019-4nlbu54e	299	9	using	use	VBG
cord-350019-4nlbu54e	299	10	an	an	DT
cord-350019-4nlbu54e	299	11	alternative	alternative	JJ
cord-350019-4nlbu54e	299	12	approach	approach	NN
cord-350019-4nlbu54e	299	13	.	.	.
cord-350019-4nlbu54e	300	1	Instead	instead	RB
cord-350019-4nlbu54e	300	2	of	of	IN
cord-350019-4nlbu54e	300	3	disrupting	disrupt	VBG
cord-350019-4nlbu54e	300	4	the	the	DT
cord-350019-4nlbu54e	300	5	chromatin	chromatin	NN
cord-350019-4nlbu54e	300	6	architecture	architecture	NN
cord-350019-4nlbu54e	300	7	or	or	CC
cord-350019-4nlbu54e	300	8	removing	remove	VBG
cord-350019-4nlbu54e	300	9	any	any	DT
cord-350019-4nlbu54e	300	10	possible	possible	JJ
cord-350019-4nlbu54e	300	11	DNA	dna	NN
cord-350019-4nlbu54e	300	12	enhancer	enhancer	NN
cord-350019-4nlbu54e	300	13	regions	region	NNS
cord-350019-4nlbu54e	300	14	,	,	,
cord-350019-4nlbu54e	300	15	they	-PRON-	PRP
cord-350019-4nlbu54e	300	16	inhibited	inhibit	VBD
cord-350019-4nlbu54e	300	17	the	the	DT
cord-350019-4nlbu54e	300	18	transcription	transcription	NN
cord-350019-4nlbu54e	300	19	of	of	IN
cord-350019-4nlbu54e	300	20	Fendrr	Fendrr	NNP
cord-350019-4nlbu54e	300	21	through	through	IN
cord-350019-4nlbu54e	300	22	the	the	DT
cord-350019-4nlbu54e	300	23	insertion	insertion	NN
cord-350019-4nlbu54e	300	24	of	of	IN
cord-350019-4nlbu54e	300	25	a	a	DT
cord-350019-4nlbu54e	300	26	poly	poly	JJ
cord-350019-4nlbu54e	300	27	-	-	HYPH
cord-350019-4nlbu54e	300	28	A	a	DT
cord-350019-4nlbu54e	300	29	cassette	cassette	NN
cord-350019-4nlbu54e	300	30	into	into	IN
cord-350019-4nlbu54e	300	31	exon1	exon1	NN
cord-350019-4nlbu54e	300	32	[	[	-LRB-
cord-350019-4nlbu54e	300	33	191	191	CD
cord-350019-4nlbu54e	300	34	]	]	-RRB-
cord-350019-4nlbu54e	300	35	.	.	.
cord-350019-4nlbu54e	301	1	Using	use	VBG
cord-350019-4nlbu54e	301	2	this	this	DT
cord-350019-4nlbu54e	301	3	lncRNA	lncrna	NN
cord-350019-4nlbu54e	301	4	knockdown	knockdown	NN
cord-350019-4nlbu54e	301	5	mouse	mouse	NN
cord-350019-4nlbu54e	301	6	design	design	NN
cord-350019-4nlbu54e	301	7	,	,	,
cord-350019-4nlbu54e	301	8	the	the	DT
cord-350019-4nlbu54e	301	9	scientists	scientist	NNS
cord-350019-4nlbu54e	301	10	determined	determine	VBD
cord-350019-4nlbu54e	301	11	that	that	IN
cord-350019-4nlbu54e	301	12	loss	loss	NN
cord-350019-4nlbu54e	301	13	of	of	IN
cord-350019-4nlbu54e	301	14	Fendrr	Fendrr	NNP
cord-350019-4nlbu54e	301	15	led	lead	VBD
cord-350019-4nlbu54e	301	16	to	to	IN
cord-350019-4nlbu54e	301	17	heart	heart	NN
cord-350019-4nlbu54e	301	18	and	and	CC
cord-350019-4nlbu54e	301	19	body	body	NN
cord-350019-4nlbu54e	301	20	wall	wall	NN
cord-350019-4nlbu54e	301	21	defects	defect	NNS
cord-350019-4nlbu54e	301	22	,	,	,
cord-350019-4nlbu54e	301	23	which	which	WDT
cord-350019-4nlbu54e	301	24	is	be	VBZ
cord-350019-4nlbu54e	301	25	slightly	slightly	RB
cord-350019-4nlbu54e	301	26	different	different	JJ
cord-350019-4nlbu54e	301	27	from	from	IN
cord-350019-4nlbu54e	301	28	the	the	DT
cord-350019-4nlbu54e	301	29	phenotype	phenotype	NN
cord-350019-4nlbu54e	301	30	in	in	IN
cord-350019-4nlbu54e	301	31	the	the	DT
cord-350019-4nlbu54e	301	32	KO	KO	NNP
cord-350019-4nlbu54e	301	33	mouse	mouse	NN
cord-350019-4nlbu54e	301	34	study	study	NN
cord-350019-4nlbu54e	301	35	.	.	.
cord-350019-4nlbu54e	302	1	Importantly	importantly	RB
cord-350019-4nlbu54e	302	2	,	,	,
cord-350019-4nlbu54e	302	3	the	the	DT
cord-350019-4nlbu54e	302	4	heart	heart	NN
cord-350019-4nlbu54e	302	5	and	and	CC
cord-350019-4nlbu54e	302	6	body	body	NN
cord-350019-4nlbu54e	302	7	wall	wall	NN
cord-350019-4nlbu54e	302	8	defects	defect	NNS
cord-350019-4nlbu54e	302	9	caused	cause	VBN
cord-350019-4nlbu54e	302	10	by	by	IN
cord-350019-4nlbu54e	302	11	the	the	DT
cord-350019-4nlbu54e	302	12	terminator	terminator	NN
cord-350019-4nlbu54e	302	13	insertion	insertion	NN
cord-350019-4nlbu54e	302	14	were	be	VBD
cord-350019-4nlbu54e	302	15	rescued	rescue	VBN
cord-350019-4nlbu54e	302	16	by	by	IN
cord-350019-4nlbu54e	302	17	a	a	DT
cord-350019-4nlbu54e	302	18	transgene	transgene	NN
cord-350019-4nlbu54e	302	19	of	of	IN
cord-350019-4nlbu54e	302	20	Fendrr	Fendrr	NNP
cord-350019-4nlbu54e	302	21	in	in	IN
cord-350019-4nlbu54e	302	22	vivo	vivo	NN
cord-350019-4nlbu54e	302	23	,	,	,
cord-350019-4nlbu54e	302	24	further	further	RB
cord-350019-4nlbu54e	302	25	confirming	confirm	VBG
cord-350019-4nlbu54e	302	26	that	that	IN
cord-350019-4nlbu54e	302	27	the	the	DT
cord-350019-4nlbu54e	302	28	phenotype	phenotype	NN
cord-350019-4nlbu54e	302	29	is	be	VBZ
cord-350019-4nlbu54e	302	30	due	due	JJ
cord-350019-4nlbu54e	302	31	to	to	IN
cord-350019-4nlbu54e	302	32	the	the	DT
cord-350019-4nlbu54e	302	33	RNA	RNA	NNP
cord-350019-4nlbu54e	302	34	while	while	IN
cord-350019-4nlbu54e	302	35	the	the	DT
cord-350019-4nlbu54e	302	36	KO	KO	NNP
cord-350019-4nlbu54e	302	37	phenotype	phenotype	NN
cord-350019-4nlbu54e	302	38	could	could	MD
cord-350019-4nlbu54e	302	39	be	be	VB
cord-350019-4nlbu54e	302	40	due	due	JJ
cord-350019-4nlbu54e	302	41	elements	element	NNS
cord-350019-4nlbu54e	302	42	within	within	IN
cord-350019-4nlbu54e	302	43	the	the	DT
cord-350019-4nlbu54e	302	44	genomic	genomic	JJ
cord-350019-4nlbu54e	302	45	DNA	dna	NN
cord-350019-4nlbu54e	302	46	[	[	-LRB-
cord-350019-4nlbu54e	302	47	191	191	CD
cord-350019-4nlbu54e	302	48	]	]	-RRB-
cord-350019-4nlbu54e	302	49	.	.	.
cord-350019-4nlbu54e	303	1	Fendrr	Fendrr	NNP
cord-350019-4nlbu54e	303	2	is	be	VBZ
cord-350019-4nlbu54e	303	3	located~4	located~4	NNP
cord-350019-4nlbu54e	303	4	kb	kb	NNP
cord-350019-4nlbu54e	303	5	downstream	downstream	NN
cord-350019-4nlbu54e	303	6	of	of	IN
cord-350019-4nlbu54e	303	7	Foxf1	Foxf1	NNP
cord-350019-4nlbu54e	303	8	and~12	and~12	CD
cord-350019-4nlbu54e	303	9	kb	kb	NNP
cord-350019-4nlbu54e	303	10	upstream	upstream	RB
cord-350019-4nlbu54e	303	11	of	of	IN
cord-350019-4nlbu54e	303	12	Irf8	Irf8	NNP
cord-350019-4nlbu54e	303	13	.	.	.
cord-350019-4nlbu54e	304	1	The	the	DT
cord-350019-4nlbu54e	304	2	observed	observed	JJ
cord-350019-4nlbu54e	304	3	phenotype	phenotype	NN
cord-350019-4nlbu54e	304	4	of	of	IN
cord-350019-4nlbu54e	304	5	the	the	DT
cord-350019-4nlbu54e	304	6	KO	KO	NNP
cord-350019-4nlbu54e	304	7	mouse	mouse	NN
cord-350019-4nlbu54e	304	8	is	be	VBZ
cord-350019-4nlbu54e	304	9	possibly	possibly	RB
cord-350019-4nlbu54e	304	10	due	due	JJ
cord-350019-4nlbu54e	304	11	to	to	IN
cord-350019-4nlbu54e	304	12	the	the	DT
cord-350019-4nlbu54e	304	13	deletion	deletion	NN
cord-350019-4nlbu54e	304	14	of	of	IN
cord-350019-4nlbu54e	304	15	an	an	DT
cord-350019-4nlbu54e	304	16	enhancer	enhancer	NN
cord-350019-4nlbu54e	304	17	element	element	NN
cord-350019-4nlbu54e	304	18	that	that	WDT
cord-350019-4nlbu54e	304	19	could	could	MD
cord-350019-4nlbu54e	304	20	impact	impact	VB
cord-350019-4nlbu54e	304	21	the	the	DT
cord-350019-4nlbu54e	304	22	expression	expression	NN
cord-350019-4nlbu54e	304	23	of	of	IN
cord-350019-4nlbu54e	304	24	protein	protein	NN
cord-350019-4nlbu54e	304	25	-	-	HYPH
cord-350019-4nlbu54e	304	26	coding	code	VBG
cord-350019-4nlbu54e	304	27	genes	gene	NNS
cord-350019-4nlbu54e	304	28	,	,	,
cord-350019-4nlbu54e	304	29	which	which	WDT
cord-350019-4nlbu54e	304	30	could	could	MD
cord-350019-4nlbu54e	304	31	have	have	VB
cord-350019-4nlbu54e	304	32	roles	role	NNS
cord-350019-4nlbu54e	304	33	in	in	IN
cord-350019-4nlbu54e	304	34	lung	lung	NN
cord-350019-4nlbu54e	304	35	development	development	NN
cord-350019-4nlbu54e	304	36	[	[	-LRB-
cord-350019-4nlbu54e	304	37	192	192	CD
cord-350019-4nlbu54e	304	38	,	,	,
cord-350019-4nlbu54e	304	39	193	193	CD
cord-350019-4nlbu54e	304	40	]	]	-RRB-
cord-350019-4nlbu54e	304	41	.	.	.
cord-350019-4nlbu54e	305	1	We	-PRON-	PRP
cord-350019-4nlbu54e	305	2	recently	recently	RB
cord-350019-4nlbu54e	305	3	used	use	VBD
cord-350019-4nlbu54e	305	4	multiple	multiple	JJ
cord-350019-4nlbu54e	305	5	genetic	genetic	JJ
cord-350019-4nlbu54e	305	6	mouse	mouse	NN
cord-350019-4nlbu54e	305	7	models	model	NNS
cord-350019-4nlbu54e	305	8	to	to	TO
cord-350019-4nlbu54e	305	9	dissect	dissect	VB
cord-350019-4nlbu54e	305	10	both	both	DT
cord-350019-4nlbu54e	305	11	cis	cis	NNP
cord-350019-4nlbu54e	305	12	and	and	CC
cord-350019-4nlbu54e	305	13	trans	trans	NNP
cord-350019-4nlbu54e	305	14	functions	function	NNS
cord-350019-4nlbu54e	305	15	of	of	IN
cord-350019-4nlbu54e	305	16	lincRNA	lincrna	RB
cord-350019-4nlbu54e	305	17	-	-	HYPH
cord-350019-4nlbu54e	305	18	Cox2	Cox2	VBN
cord-350019-4nlbu54e	305	19	in	in	IN
cord-350019-4nlbu54e	305	20	vivo	vivo	NN
cord-350019-4nlbu54e	305	21	[	[	-LRB-
cord-350019-4nlbu54e	305	22	46	46	CD
cord-350019-4nlbu54e	305	23	]	]	-RRB-
cord-350019-4nlbu54e	305	24	.	.	.
cord-350019-4nlbu54e	306	1	Working	work	VBG
cord-350019-4nlbu54e	306	2	with	with	IN
cord-350019-4nlbu54e	306	3	a	a	DT
cord-350019-4nlbu54e	306	4	complete	complete	JJ
cord-350019-4nlbu54e	306	5	lincRNA	lincrna	RB
cord-350019-4nlbu54e	306	6	-	-	HYPH
cord-350019-4nlbu54e	306	7	Cox2	cox2	JJ
cord-350019-4nlbu54e	306	8	knockout	knockout	NN
cord-350019-4nlbu54e	306	9	[	[	-LRB-
cord-350019-4nlbu54e	306	10	185	185	CD
cord-350019-4nlbu54e	306	11	]	]	-RRB-
cord-350019-4nlbu54e	306	12	,	,	,
cord-350019-4nlbu54e	306	13	in	in	IN
cord-350019-4nlbu54e	306	14	which	which	WDT
cord-350019-4nlbu54e	306	15	the	the	DT
cord-350019-4nlbu54e	306	16	gene	gene	NN
cord-350019-4nlbu54e	306	17	is	be	VBZ
cord-350019-4nlbu54e	306	18	replaced	replace	VBN
cord-350019-4nlbu54e	306	19	with	with	IN
cord-350019-4nlbu54e	306	20	a	a	DT
cord-350019-4nlbu54e	306	21	LacZ	LacZ	NNP
cord-350019-4nlbu54e	306	22	cassette	cassette	NN
cord-350019-4nlbu54e	306	23	,	,	,
cord-350019-4nlbu54e	306	24	we	-PRON-	PRP
cord-350019-4nlbu54e	306	25	observed	observe	VBD
cord-350019-4nlbu54e	306	26	a	a	DT
cord-350019-4nlbu54e	306	27	strong	strong	JJ
cord-350019-4nlbu54e	306	28	cis	cis	NNP
cord-350019-4nlbu54e	306	29	defect	defect	NN
cord-350019-4nlbu54e	306	30	on	on	IN
cord-350019-4nlbu54e	306	31	the	the	DT
cord-350019-4nlbu54e	306	32	neighboring	neighbor	VBG
cord-350019-4nlbu54e	306	33	protein	protein	NN
cord-350019-4nlbu54e	306	34	-	-	HYPH
cord-350019-4nlbu54e	306	35	coding	code	VBG
cord-350019-4nlbu54e	306	36	gene	gene	NN
cord-350019-4nlbu54e	306	37	Ptgs2	Ptgs2	NNS
cord-350019-4nlbu54e	306	38	.	.	.
cord-350019-4nlbu54e	307	1	From	from	IN
cord-350019-4nlbu54e	307	2	these	these	DT
cord-350019-4nlbu54e	307	3	studies	study	NNS
cord-350019-4nlbu54e	307	4	,	,	,
cord-350019-4nlbu54e	307	5	we	-PRON-	PRP
cord-350019-4nlbu54e	307	6	concluded	conclude	VBD
cord-350019-4nlbu54e	307	7	that	that	IN
cord-350019-4nlbu54e	307	8	lincRNA	lincrna	RB
cord-350019-4nlbu54e	307	9	-	-	HYPH
cord-350019-4nlbu54e	307	10	Cox2	Cox2	NNP
cord-350019-4nlbu54e	307	11	functions	function	NNS
cord-350019-4nlbu54e	307	12	in	in	IN
cord-350019-4nlbu54e	307	13	cis	cis	NNP
cord-350019-4nlbu54e	307	14	through	through	IN
cord-350019-4nlbu54e	307	15	an	an	DT
cord-350019-4nlbu54e	307	16	enhancer	enhancer	NN
cord-350019-4nlbu54e	307	17	RNA	RNA	NNP
cord-350019-4nlbu54e	307	18	mechanism	mechanism	NN
cord-350019-4nlbu54e	307	19	to	to	TO
cord-350019-4nlbu54e	307	20	regulate	regulate	VB
cord-350019-4nlbu54e	307	21	its	-PRON-	PRP$
cord-350019-4nlbu54e	307	22	neighboring	neighboring	NN
cord-350019-4nlbu54e	307	23	gene	gene	NN
cord-350019-4nlbu54e	307	24	Ptgs2	Ptgs2	NNS
cord-350019-4nlbu54e	307	25	[	[	-LRB-
cord-350019-4nlbu54e	307	26	46	46	CD
cord-350019-4nlbu54e	307	27	]	]	-RRB-
cord-350019-4nlbu54e	307	28	.	.	.
cord-350019-4nlbu54e	308	1	In	in	IN
cord-350019-4nlbu54e	308	2	order	order	NN
cord-350019-4nlbu54e	308	3	to	to	TO
cord-350019-4nlbu54e	308	4	determine	determine	VB
cord-350019-4nlbu54e	308	5	how	how	WRB
cord-350019-4nlbu54e	308	6	lincRNA	lincrna	RB
cord-350019-4nlbu54e	308	7	-	-	HYPH
cord-350019-4nlbu54e	308	8	Cox2	Cox2	NNP
cord-350019-4nlbu54e	308	9	functions	function	NNS
cord-350019-4nlbu54e	308	10	in	in	IN
cord-350019-4nlbu54e	308	11	trans	trans	NNP
cord-350019-4nlbu54e	308	12	to	to	TO
cord-350019-4nlbu54e	308	13	regulate	regulate	VB
cord-350019-4nlbu54e	308	14	genes	gene	NNS
cord-350019-4nlbu54e	308	15	independent	independent	JJ
cord-350019-4nlbu54e	308	16	of	of	IN
cord-350019-4nlbu54e	308	17	its	-PRON-	PRP$
cord-350019-4nlbu54e	308	18	cis	cis	NNP
cord-350019-4nlbu54e	308	19	effects	effect	NNS
cord-350019-4nlbu54e	308	20	,	,	,
cord-350019-4nlbu54e	308	21	we	-PRON-	PRP
cord-350019-4nlbu54e	308	22	generated	generate	VBD
cord-350019-4nlbu54e	308	23	a	a	DT
cord-350019-4nlbu54e	308	24	mutant	mutant	JJ
cord-350019-4nlbu54e	308	25	/	/	SYM
cord-350019-4nlbu54e	308	26	intronless	intronless	NN
cord-350019-4nlbu54e	308	27	mouse	mouse	NN
cord-350019-4nlbu54e	308	28	by	by	IN
cord-350019-4nlbu54e	308	29	targeting	target	VBG
cord-350019-4nlbu54e	308	30	the	the	DT
cord-350019-4nlbu54e	308	31	splice	splice	NN
cord-350019-4nlbu54e	308	32	sites	site	NNS
cord-350019-4nlbu54e	308	33	of	of	IN
cord-350019-4nlbu54e	308	34	lincRNA	lincrna	RB
cord-350019-4nlbu54e	308	35	-	-	HYPH
cord-350019-4nlbu54e	308	36	Cox2	Cox2	NNP
cord-350019-4nlbu54e	308	37	using	use	VBG
cord-350019-4nlbu54e	308	38	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	308	39	/	/	SYM
cord-350019-4nlbu54e	308	40	Cas9	Cas9	NNP
cord-350019-4nlbu54e	308	41	.	.	.
cord-350019-4nlbu54e	309	1	This	this	DT
cord-350019-4nlbu54e	309	2	mouse	mouse	NN
cord-350019-4nlbu54e	309	3	represents	represent	VBZ
cord-350019-4nlbu54e	309	4	a	a	DT
cord-350019-4nlbu54e	309	5	knockdown	knockdown	NN
cord-350019-4nlbu54e	309	6	mouse	mouse	NN
cord-350019-4nlbu54e	309	7	,	,	,
cord-350019-4nlbu54e	309	8	and	and	CC
cord-350019-4nlbu54e	309	9	because	because	IN
cord-350019-4nlbu54e	309	10	there	there	EX
cord-350019-4nlbu54e	309	11	is	be	VBZ
cord-350019-4nlbu54e	309	12	a	a	DT
cord-350019-4nlbu54e	309	13	low	low	JJ
cord-350019-4nlbu54e	309	14	level	level	NN
cord-350019-4nlbu54e	309	15	of	of	IN
cord-350019-4nlbu54e	309	16	transcription	transcription	NN
cord-350019-4nlbu54e	309	17	of	of	IN
cord-350019-4nlbu54e	309	18	lincRNA	lincrna	RB
cord-350019-4nlbu54e	309	19	-	-	HYPH
cord-350019-4nlbu54e	309	20	Cox2	Cox2	NNP
cord-350019-4nlbu54e	309	21	,	,	,
cord-350019-4nlbu54e	309	22	Ptgs2	Ptgs2	NNS
cord-350019-4nlbu54e	309	23	levels	level	NNS
cord-350019-4nlbu54e	309	24	are	be	VBP
cord-350019-4nlbu54e	309	25	the	the	DT
cord-350019-4nlbu54e	309	26	same	same	JJ
cord-350019-4nlbu54e	309	27	as	as	IN
cord-350019-4nlbu54e	309	28	WT	WT	NNP
cord-350019-4nlbu54e	309	29	.	.	.
cord-350019-4nlbu54e	310	1	LincRNA	lincrna	LS
cord-350019-4nlbu54e	310	2	-	-	:
cord-350019-4nlbu54e	310	3	Cox2	Cox2	NNP
cord-350019-4nlbu54e	310	4	is	be	VBZ
cord-350019-4nlbu54e	310	5	not	not	RB
cord-350019-4nlbu54e	310	6	inducible	inducible	JJ
cord-350019-4nlbu54e	310	7	in	in	IN
cord-350019-4nlbu54e	310	8	the	the	DT
cord-350019-4nlbu54e	310	9	mutant	mutant	JJ
cord-350019-4nlbu54e	310	10	mouse	mouse	NN
cord-350019-4nlbu54e	310	11	,	,	,
cord-350019-4nlbu54e	310	12	probably	probably	RB
cord-350019-4nlbu54e	310	13	because	because	IN
cord-350019-4nlbu54e	310	14	of	of	IN
cord-350019-4nlbu54e	310	15	transcript	transcript	NN
cord-350019-4nlbu54e	310	16	instability	instability	NN
cord-350019-4nlbu54e	310	17	due	due	IN
cord-350019-4nlbu54e	310	18	to	to	IN
cord-350019-4nlbu54e	310	19	the	the	DT
cord-350019-4nlbu54e	310	20	lack	lack	NN
cord-350019-4nlbu54e	310	21	of	of	IN
cord-350019-4nlbu54e	310	22	splicing	splicing	NN
cord-350019-4nlbu54e	310	23	,	,	,
cord-350019-4nlbu54e	310	24	enabling	enable	VBG
cord-350019-4nlbu54e	310	25	us	-PRON-	PRP
cord-350019-4nlbu54e	310	26	to	to	TO
cord-350019-4nlbu54e	310	27	study	study	VB
cord-350019-4nlbu54e	310	28	its	-PRON-	PRP$
cord-350019-4nlbu54e	310	29	trans	trans	JJ
cord-350019-4nlbu54e	310	30	regulatory	regulatory	JJ
cord-350019-4nlbu54e	310	31	roles	role	NNS
cord-350019-4nlbu54e	310	32	.	.	.
cord-350019-4nlbu54e	311	1	Similar	similar	JJ
cord-350019-4nlbu54e	311	2	to	to	IN
cord-350019-4nlbu54e	311	3	our	-PRON-	PRP$
cord-350019-4nlbu54e	311	4	early	early	JJ
cord-350019-4nlbu54e	311	5	in	in	IN
cord-350019-4nlbu54e	311	6	vitro	vitro	FW
cord-350019-4nlbu54e	311	7	work	work	NN
cord-350019-4nlbu54e	311	8	we	-PRON-	PRP
cord-350019-4nlbu54e	311	9	observed	observe	VBD
cord-350019-4nlbu54e	311	10	using	use	VBG
cord-350019-4nlbu54e	311	11	an	an	DT
cord-350019-4nlbu54e	311	12	LPS	LPS	NNP
cord-350019-4nlbu54e	311	13	shock	shock	NN
cord-350019-4nlbu54e	311	14	model	model	NN
cord-350019-4nlbu54e	311	15	that	that	IN
cord-350019-4nlbu54e	311	16	many	many	JJ
cord-350019-4nlbu54e	311	17	genes	gene	NNS
cord-350019-4nlbu54e	311	18	are	be	VBP
cord-350019-4nlbu54e	311	19	both	both	DT
cord-350019-4nlbu54e	311	20	up	up	RB
cord-350019-4nlbu54e	311	21	and	and	CC
cord-350019-4nlbu54e	311	22	downregulated	downregulate	VBD
cord-350019-4nlbu54e	311	23	in	in	IN
cord-350019-4nlbu54e	311	24	the	the	DT
cord-350019-4nlbu54e	311	25	serum	serum	NN
cord-350019-4nlbu54e	311	26	of	of	IN
cord-350019-4nlbu54e	311	27	mutant	mutant	JJ
cord-350019-4nlbu54e	311	28	mice	mouse	NNS
cord-350019-4nlbu54e	311	29	indicating	indicate	VBG
cord-350019-4nlbu54e	311	30	that	that	IN
cord-350019-4nlbu54e	311	31	lincRNA	lincRNA	VBG
cord-350019-4nlbu54e	311	32	-	-	:
cord-350019-4nlbu54e	311	33	Cox2	Cox2	NNP
cord-350019-4nlbu54e	311	34	can	can	MD
cord-350019-4nlbu54e	311	35	indeed	indeed	RB
cord-350019-4nlbu54e	311	36	function	function	VB
cord-350019-4nlbu54e	311	37	in	in	IN
cord-350019-4nlbu54e	311	38	trans	trans	NNP
cord-350019-4nlbu54e	311	39	to	to	TO
cord-350019-4nlbu54e	311	40	regulate	regulate	VB
cord-350019-4nlbu54e	311	41	immune	immune	JJ
cord-350019-4nlbu54e	311	42	genes	gene	NNS
cord-350019-4nlbu54e	311	43	in	in	IN
cord-350019-4nlbu54e	311	44	vivo	vivo	NN
cord-350019-4nlbu54e	311	45	[	[	-LRB-
cord-350019-4nlbu54e	311	46	46	46	CD
cord-350019-4nlbu54e	311	47	]	]	-RRB-
cord-350019-4nlbu54e	311	48	.	.	.
cord-350019-4nlbu54e	312	1	To	to	TO
cord-350019-4nlbu54e	312	2	prove	prove	VB
cord-350019-4nlbu54e	312	3	genetically	genetically	RB
cord-350019-4nlbu54e	312	4	that	that	IN
cord-350019-4nlbu54e	312	5	a	a	DT
cord-350019-4nlbu54e	312	6	lncRNA	lncrna	NN
cord-350019-4nlbu54e	312	7	is	be	VBZ
cord-350019-4nlbu54e	312	8	functioning	function	VBG
cord-350019-4nlbu54e	312	9	in	in	IN
cord-350019-4nlbu54e	312	10	trans	trans	NNP
cord-350019-4nlbu54e	312	11	,	,	,
cord-350019-4nlbu54e	312	12	a	a	DT
cord-350019-4nlbu54e	312	13	trans	trans	NNP
cord-350019-4nlbu54e	312	14	rescue	rescue	NN
cord-350019-4nlbu54e	312	15	experiment	experiment	NN
cord-350019-4nlbu54e	312	16	can	can	MD
cord-350019-4nlbu54e	312	17	be	be	VB
cord-350019-4nlbu54e	312	18	performed	perform	VBN
cord-350019-4nlbu54e	312	19	using	use	VBG
cord-350019-4nlbu54e	312	20	transgenic	transgenic	JJ
cord-350019-4nlbu54e	312	21	mice	mouse	NNS
cord-350019-4nlbu54e	312	22	that	that	WDT
cord-350019-4nlbu54e	312	23	constitutively	constitutively	RB
cord-350019-4nlbu54e	312	24	express	express	VBP
cord-350019-4nlbu54e	312	25	a	a	DT
cord-350019-4nlbu54e	312	26	lncRNA	lncrna	NN
cord-350019-4nlbu54e	312	27	.	.	.
cord-350019-4nlbu54e	313	1	This	this	DT
cord-350019-4nlbu54e	313	2	rescue	rescue	NN
cord-350019-4nlbu54e	313	3	strategy	strategy	NN
cord-350019-4nlbu54e	313	4	has	have	VBZ
cord-350019-4nlbu54e	313	5	been	be	VBN
cord-350019-4nlbu54e	313	6	utilized	utilize	VBN
cord-350019-4nlbu54e	313	7	in	in	IN
cord-350019-4nlbu54e	313	8	some	some	DT
cord-350019-4nlbu54e	313	9	studies	study	NNS
cord-350019-4nlbu54e	313	10	including	include	VBG
cord-350019-4nlbu54e	313	11	Evf2	Evf2	NNP
cord-350019-4nlbu54e	313	12	[	[	-LRB-
cord-350019-4nlbu54e	313	13	194	194	CD
cord-350019-4nlbu54e	313	14	,	,	,
cord-350019-4nlbu54e	313	15	195	195	CD
cord-350019-4nlbu54e	313	16	]	]	-RRB-
cord-350019-4nlbu54e	314	1	,	,	,
cord-350019-4nlbu54e	314	2	Jpx	Jpx	NNP
cord-350019-4nlbu54e	314	3	[	[	-LRB-
cord-350019-4nlbu54e	314	4	196	196	CD
cord-350019-4nlbu54e	314	5	]	]	-RRB-
cord-350019-4nlbu54e	314	6	,	,	,
cord-350019-4nlbu54e	314	7	as	as	RB
cord-350019-4nlbu54e	314	8	well	well	RB
cord-350019-4nlbu54e	314	9	as	as	IN
cord-350019-4nlbu54e	314	10	Pnky	Pnky	NNP
cord-350019-4nlbu54e	314	11	[	[	-LRB-
cord-350019-4nlbu54e	314	12	197	197	CD
cord-350019-4nlbu54e	314	13	]	]	-RRB-
cord-350019-4nlbu54e	314	14	which	which	WDT
cord-350019-4nlbu54e	314	15	both	both	DT
cord-350019-4nlbu54e	314	16	demonstrate	demonstrate	VBP
cord-350019-4nlbu54e	314	17	successful	successful	JJ
cord-350019-4nlbu54e	314	18	rescue	rescue	NN
cord-350019-4nlbu54e	314	19	experiments	experiment	NNS
cord-350019-4nlbu54e	314	20	where	where	WRB
cord-350019-4nlbu54e	314	21	the	the	DT
cord-350019-4nlbu54e	314	22	phenotype	phenotype	NN
cord-350019-4nlbu54e	314	23	from	from	IN
cord-350019-4nlbu54e	314	24	germline	germline	JJ
cord-350019-4nlbu54e	314	25	ablation	ablation	NN
cord-350019-4nlbu54e	314	26	of	of	IN
cord-350019-4nlbu54e	314	27	a	a	DT
cord-350019-4nlbu54e	314	28	lncRNA	lncrna	NN
cord-350019-4nlbu54e	314	29	is	be	VBZ
cord-350019-4nlbu54e	314	30	rescued	rescue	VBN
cord-350019-4nlbu54e	314	31	through	through	IN
cord-350019-4nlbu54e	314	32	generation	generation	NN
cord-350019-4nlbu54e	314	33	and	and	CC
cord-350019-4nlbu54e	314	34	crossing	crossing	NN
cord-350019-4nlbu54e	314	35	with	with	IN
cord-350019-4nlbu54e	314	36	a	a	DT
cord-350019-4nlbu54e	314	37	transgenic	transgenic	JJ
cord-350019-4nlbu54e	314	38	animal	animal	NN
cord-350019-4nlbu54e	314	39	.	.	.
cord-350019-4nlbu54e	315	1	Understanding	understand	VBG
cord-350019-4nlbu54e	315	2	the	the	DT
cord-350019-4nlbu54e	315	3	mechanism	mechanism	NN
cord-350019-4nlbu54e	315	4	of	of	IN
cord-350019-4nlbu54e	315	5	action	action	NN
cord-350019-4nlbu54e	315	6	of	of	IN
cord-350019-4nlbu54e	315	7	a	a	DT
cord-350019-4nlbu54e	315	8	lncRNA	lncrna	NN
cord-350019-4nlbu54e	315	9	LncRNAs	lncrna	NNS
cord-350019-4nlbu54e	315	10	are	be	VBP
cord-350019-4nlbu54e	315	11	immensely	immensely	RB
cord-350019-4nlbu54e	315	12	adaptable	adaptable	JJ
cord-350019-4nlbu54e	315	13	molecules	molecule	NNS
cord-350019-4nlbu54e	315	14	that	that	WDT
cord-350019-4nlbu54e	315	15	are	be	VBP
cord-350019-4nlbu54e	315	16	capable	capable	JJ
cord-350019-4nlbu54e	315	17	of	of	IN
cord-350019-4nlbu54e	315	18	working	work	VBG
cord-350019-4nlbu54e	315	19	through	through	IN
cord-350019-4nlbu54e	315	20	RNA	RNA	NNP
cord-350019-4nlbu54e	315	21	-	-	HYPH
cord-350019-4nlbu54e	315	22	RNA	RNA	NNP
cord-350019-4nlbu54e	315	23	,	,	,
cord-350019-4nlbu54e	315	24	RNA	RNA	NNP
cord-350019-4nlbu54e	315	25	-	-	HYPH
cord-350019-4nlbu54e	315	26	DNA	DNA	NNP
cord-350019-4nlbu54e	315	27	,	,	,
cord-350019-4nlbu54e	315	28	or	or	CC
cord-350019-4nlbu54e	315	29	RNA	rna	NN
cord-350019-4nlbu54e	315	30	-	-	HYPH
cord-350019-4nlbu54e	315	31	protein	protein	NN
cord-350019-4nlbu54e	315	32	interactions	interaction	NNS
cord-350019-4nlbu54e	315	33	.	.	.
cord-350019-4nlbu54e	316	1	RNA	RNA	NNP
cord-350019-4nlbu54e	316	2	-	-	HYPH
cord-350019-4nlbu54e	316	3	directed	direct	VBN
cord-350019-4nlbu54e	316	4	technologies	technology	NNS
cord-350019-4nlbu54e	316	5	such	such	JJ
cord-350019-4nlbu54e	316	6	as	as	IN
cord-350019-4nlbu54e	316	7	Chromatin	Chromatin	NNP
cord-350019-4nlbu54e	316	8	Isolation	Isolation	NNP
cord-350019-4nlbu54e	316	9	by	by	IN
cord-350019-4nlbu54e	316	10	RNA	RNA	NNP
cord-350019-4nlbu54e	316	11	Purification	Purification	NNP
cord-350019-4nlbu54e	316	12	(	(	-LRB-
cord-350019-4nlbu54e	316	13	ChIRP	ChIRP	NNP
cord-350019-4nlbu54e	316	14	)	)	-RRB-
cord-350019-4nlbu54e	317	1	[	[	-LRB-
cord-350019-4nlbu54e	317	2	198	198	CD
cord-350019-4nlbu54e	317	3	,	,	,
cord-350019-4nlbu54e	317	4	199	199	CD
cord-350019-4nlbu54e	317	5	]	]	-RRB-
cord-350019-4nlbu54e	317	6	or	or	CC
cord-350019-4nlbu54e	317	7	RNA	RNA	NNP
cord-350019-4nlbu54e	317	8	antisense	antisense	NN
cord-350019-4nlbu54e	317	9	purification	purification	NN
cord-350019-4nlbu54e	317	10	(	(	-LRB-
cord-350019-4nlbu54e	317	11	RAP	RAP	NNP
cord-350019-4nlbu54e	317	12	)	)	-RRB-
cord-350019-4nlbu54e	317	13	[	[	-LRB-
cord-350019-4nlbu54e	317	14	200	200	CD
cord-350019-4nlbu54e	317	15	,	,	,
cord-350019-4nlbu54e	317	16	201	201	CD
cord-350019-4nlbu54e	317	17	]	]	-RRB-
cord-350019-4nlbu54e	317	18	,	,	,
cord-350019-4nlbu54e	317	19	will	will	MD
cord-350019-4nlbu54e	317	20	help	help	VB
cord-350019-4nlbu54e	317	21	uncover	uncover	VB
cord-350019-4nlbu54e	317	22	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	317	23	interactomes	interactomes	NNP
cord-350019-4nlbu54e	317	24	for	for	IN
cord-350019-4nlbu54e	317	25	RNA	RNA	NNP
cord-350019-4nlbu54e	317	26	,	,	,
cord-350019-4nlbu54e	317	27	genomic	genomic	JJ
cord-350019-4nlbu54e	317	28	or	or	CC
cord-350019-4nlbu54e	317	29	protein	protein	NN
cord-350019-4nlbu54e	317	30	partners	partner	NNS
cord-350019-4nlbu54e	317	31	for	for	IN
cord-350019-4nlbu54e	317	32	highly	highly	RB
cord-350019-4nlbu54e	317	33	expressed	express	VBN
cord-350019-4nlbu54e	317	34	candidates	candidate	NNS
cord-350019-4nlbu54e	317	35	.	.	.
cord-350019-4nlbu54e	318	1	If	if	IN
cord-350019-4nlbu54e	318	2	a	a	DT
cord-350019-4nlbu54e	318	3	candidate	candidate	NN
cord-350019-4nlbu54e	318	4	is	be	VBZ
cord-350019-4nlbu54e	318	5	lowly	lowly	RB
cord-350019-4nlbu54e	318	6	expressed	express	VBN
cord-350019-4nlbu54e	318	7	,	,	,
cord-350019-4nlbu54e	318	8	one	one	PRP
cord-350019-4nlbu54e	318	9	can	can	MD
cord-350019-4nlbu54e	318	10	exogenously	exogenously	RB
cord-350019-4nlbu54e	318	11	introduce	introduce	VB
cord-350019-4nlbu54e	318	12	a	a	DT
cord-350019-4nlbu54e	318	13	biotinylated	biotinylated	JJ
cord-350019-4nlbu54e	318	14	form	form	NN
cord-350019-4nlbu54e	318	15	of	of	IN
cord-350019-4nlbu54e	318	16	the	the	DT
cord-350019-4nlbu54e	318	17	lncRNA	lncrna	NN
cord-350019-4nlbu54e	318	18	using	use	VBG
cord-350019-4nlbu54e	318	19	the	the	DT
cord-350019-4nlbu54e	318	20	RNA	RNA	NNP
cord-350019-4nlbu54e	318	21	pull	pull	VB
cord-350019-4nlbu54e	318	22	-	-	HYPH
cord-350019-4nlbu54e	318	23	down	down	RP
cord-350019-4nlbu54e	318	24	method	method	NN
cord-350019-4nlbu54e	318	25	,	,	,
cord-350019-4nlbu54e	318	26	which	which	WDT
cord-350019-4nlbu54e	318	27	we	-PRON-	PRP
cord-350019-4nlbu54e	318	28	have	have	VBP
cord-350019-4nlbu54e	318	29	successfully	successfully	RB
cord-350019-4nlbu54e	318	30	used	use	VBN
cord-350019-4nlbu54e	318	31	to	to	TO
cord-350019-4nlbu54e	318	32	identify	identify	VB
cord-350019-4nlbu54e	318	33	binding	bind	VBG
cord-350019-4nlbu54e	318	34	partners	partner	NNS
cord-350019-4nlbu54e	318	35	for	for	IN
cord-350019-4nlbu54e	318	36	lincRNA	lincrna	RB
cord-350019-4nlbu54e	318	37	-	-	HYPH
cord-350019-4nlbu54e	318	38	Cox2	Cox2	NNP
cord-350019-4nlbu54e	318	39	.	.	.
cord-350019-4nlbu54e	319	1	This	this	DT
cord-350019-4nlbu54e	319	2	has	have	VBZ
cord-350019-4nlbu54e	319	3	been	be	VBN
cord-350019-4nlbu54e	319	4	performed	perform	VBN
cord-350019-4nlbu54e	319	5	for	for	IN
cord-350019-4nlbu54e	319	6	many	many	JJ
cord-350019-4nlbu54e	319	7	lncRNAs	lncRNAs	NNPS
cord-350019-4nlbu54e	319	8	[	[	-LRB-
cord-350019-4nlbu54e	319	9	42	42	CD
cord-350019-4nlbu54e	319	10	,	,	,
cord-350019-4nlbu54e	319	11	202	202	CD
cord-350019-4nlbu54e	319	12	,	,	,
cord-350019-4nlbu54e	319	13	203	203	CD
cord-350019-4nlbu54e	319	14	]	]	-RRB-
cord-350019-4nlbu54e	319	15	.	.	.
cord-350019-4nlbu54e	320	1	Functions	function	NNS
cord-350019-4nlbu54e	320	2	of	of	IN
cord-350019-4nlbu54e	320	3	lncRNAs	lncRNAs	NNPS
cord-350019-4nlbu54e	320	4	are	be	VBP
cord-350019-4nlbu54e	320	5	associated	associate	VBN
cord-350019-4nlbu54e	320	6	with	with	IN
cord-350019-4nlbu54e	320	7	their	-PRON-	PRP$
cord-350019-4nlbu54e	320	8	subcellular	subcellular	JJ
cord-350019-4nlbu54e	320	9	fates	fate	NNS
cord-350019-4nlbu54e	320	10	.	.	.
cord-350019-4nlbu54e	321	1	Web	web	NN
cord-350019-4nlbu54e	321	2	servers	server	NNS
cord-350019-4nlbu54e	321	3	can	can	MD
cord-350019-4nlbu54e	321	4	assist	assist	VB
cord-350019-4nlbu54e	321	5	in	in	IN
cord-350019-4nlbu54e	321	6	quickly	quickly	RB
cord-350019-4nlbu54e	321	7	assessing	assess	VBG
cord-350019-4nlbu54e	321	8	experimentally	experimentally	RB
cord-350019-4nlbu54e	321	9	determined	determined	JJ
cord-350019-4nlbu54e	321	10	or	or	CC
cord-350019-4nlbu54e	321	11	predictive	predictive	JJ
cord-350019-4nlbu54e	321	12	RNA	RNA	NNP
cord-350019-4nlbu54e	321	13	-	-	HYPH
cord-350019-4nlbu54e	321	14	RNA	RNA	NNP
cord-350019-4nlbu54e	321	15	interactions	interaction	NNS
cord-350019-4nlbu54e	321	16	[	[	-LRB-
cord-350019-4nlbu54e	321	17	204	204	CD
cord-350019-4nlbu54e	321	18	]	]	-RRB-
cord-350019-4nlbu54e	321	19	or	or	CC
cord-350019-4nlbu54e	321	20	even	even	RB
cord-350019-4nlbu54e	321	21	RNA	rna	NN
cord-350019-4nlbu54e	321	22	-	-	HYPH
cord-350019-4nlbu54e	321	23	protein	protein	NN
cord-350019-4nlbu54e	321	24	interactions	interaction	NNS
cord-350019-4nlbu54e	321	25	[	[	-LRB-
cord-350019-4nlbu54e	321	26	205	205	CD
cord-350019-4nlbu54e	321	27	,	,	,
cord-350019-4nlbu54e	321	28	206	206	CD
cord-350019-4nlbu54e	321	29	]	]	-RRB-
cord-350019-4nlbu54e	321	30	.	.	.
cord-350019-4nlbu54e	322	1	Depending	depend	VBG
cord-350019-4nlbu54e	322	2	on	on	IN
cord-350019-4nlbu54e	322	3	the	the	DT
cord-350019-4nlbu54e	322	4	subcellular	subcellular	JJ
cord-350019-4nlbu54e	322	5	or	or	CC
cord-350019-4nlbu54e	322	6	extracellular	extracellular	JJ
cord-350019-4nlbu54e	322	7	compartmental	compartmental	JJ
cord-350019-4nlbu54e	322	8	localization	localization	NN
cord-350019-4nlbu54e	322	9	of	of	IN
cord-350019-4nlbu54e	322	10	a	a	DT
cord-350019-4nlbu54e	322	11	lncRNA	lncrna	NN
cord-350019-4nlbu54e	322	12	,	,	,
cord-350019-4nlbu54e	322	13	this	this	DT
cord-350019-4nlbu54e	322	14	patterning	patterning	NN
cord-350019-4nlbu54e	322	15	will	will	MD
cord-350019-4nlbu54e	322	16	elude	elude	VB
cord-350019-4nlbu54e	322	17	to	to	IN
cord-350019-4nlbu54e	322	18	the	the	DT
cord-350019-4nlbu54e	322	19	regulatory	regulatory	JJ
cord-350019-4nlbu54e	322	20	role	role	NN
cord-350019-4nlbu54e	322	21	of	of	IN
cord-350019-4nlbu54e	322	22	the	the	DT
cord-350019-4nlbu54e	322	23	gene	gene	NN
cord-350019-4nlbu54e	322	24	,	,	,
cord-350019-4nlbu54e	322	25	as	as	RB
cord-350019-4nlbu54e	322	26	well	well	RB
cord-350019-4nlbu54e	322	27	as	as	IN
cord-350019-4nlbu54e	322	28	how	how	WRB
cord-350019-4nlbu54e	322	29	a	a	DT
cord-350019-4nlbu54e	322	30	lncRNA	lncrna	NN
cord-350019-4nlbu54e	322	31	might	may	MD
cord-350019-4nlbu54e	322	32	execute	execute	VB
cord-350019-4nlbu54e	322	33	its	-PRON-	PRP$
cord-350019-4nlbu54e	322	34	function	function	NN
cord-350019-4nlbu54e	322	35	[	[	-LRB-
cord-350019-4nlbu54e	322	36	207	207	CD
cord-350019-4nlbu54e	322	37	]	]	-RRB-
cord-350019-4nlbu54e	322	38	[	[	-LRB-
cord-350019-4nlbu54e	322	39	208	208	CD
cord-350019-4nlbu54e	322	40	]	]	-RRB-
cord-350019-4nlbu54e	322	41	[	[	-LRB-
cord-350019-4nlbu54e	322	42	209	209	CD
cord-350019-4nlbu54e	322	43	]	]	-RRB-
cord-350019-4nlbu54e	322	44	.	.	.
cord-350019-4nlbu54e	323	1	Some	some	DT
cord-350019-4nlbu54e	323	2	LncRNAs	lncrna	NNS
cord-350019-4nlbu54e	323	3	that	that	WDT
cord-350019-4nlbu54e	323	4	are	be	VBP
cord-350019-4nlbu54e	323	5	localized	localize	VBN
cord-350019-4nlbu54e	323	6	to	to	IN
cord-350019-4nlbu54e	323	7	the	the	DT
cord-350019-4nlbu54e	323	8	nucleus	nucleus	NN
cord-350019-4nlbu54e	323	9	or	or	CC
cord-350019-4nlbu54e	323	10	chromatin	chromatin	NN
cord-350019-4nlbu54e	323	11	have	have	VBP
cord-350019-4nlbu54e	323	12	been	be	VBN
cord-350019-4nlbu54e	323	13	experimentally	experimentally	RB
cord-350019-4nlbu54e	323	14	shown	show	VBN
cord-350019-4nlbu54e	323	15	to	to	TO
cord-350019-4nlbu54e	323	16	function	function	VB
cord-350019-4nlbu54e	323	17	in	in	IN
cord-350019-4nlbu54e	323	18	cis	cis	NNP
cord-350019-4nlbu54e	323	19	to	to	TO
cord-350019-4nlbu54e	323	20	regulate	regulate	VB
cord-350019-4nlbu54e	323	21	the	the	DT
cord-350019-4nlbu54e	323	22	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	323	23	expression	expression	NN
cord-350019-4nlbu54e	323	24	of	of	IN
cord-350019-4nlbu54e	323	25	a	a	DT
cord-350019-4nlbu54e	323	26	neighboring	neighbor	VBG
cord-350019-4nlbu54e	323	27	gene	gene	NN
cord-350019-4nlbu54e	323	28	,	,	,
cord-350019-4nlbu54e	323	29	or	or	CC
cord-350019-4nlbu54e	323	30	in	in	IN
cord-350019-4nlbu54e	323	31	trans	trans	NNP
cord-350019-4nlbu54e	323	32	to	to	TO
cord-350019-4nlbu54e	323	33	regulate	regulate	VB
cord-350019-4nlbu54e	323	34	the	the	DT
cord-350019-4nlbu54e	323	35	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	323	36	regulation	regulation	NN
cord-350019-4nlbu54e	323	37	of	of	IN
cord-350019-4nlbu54e	323	38	a	a	DT
cord-350019-4nlbu54e	323	39	subclass	subclass	NN
cord-350019-4nlbu54e	323	40	of	of	IN
cord-350019-4nlbu54e	323	41	genes	gene	NNS
cord-350019-4nlbu54e	323	42	through	through	IN
cord-350019-4nlbu54e	323	43	the	the	DT
cord-350019-4nlbu54e	323	44	interactions	interaction	NNS
cord-350019-4nlbu54e	323	45	between	between	IN
cord-350019-4nlbu54e	323	46	heterogeneous	heterogeneous	JJ
cord-350019-4nlbu54e	323	47	nuclear	nuclear	JJ
cord-350019-4nlbu54e	323	48	ribonucleoproteins	ribonucleoprotein	NNS
cord-350019-4nlbu54e	323	49	(	(	-LRB-
cord-350019-4nlbu54e	323	50	hnRNPs	hnRNPs	NNP
cord-350019-4nlbu54e	323	51	)	)	-RRB-
cord-350019-4nlbu54e	323	52	[	[	-LRB-
cord-350019-4nlbu54e	323	53	42	42	CD
cord-350019-4nlbu54e	323	54	,	,	,
cord-350019-4nlbu54e	323	55	54	54	CD
cord-350019-4nlbu54e	323	56	,	,	,
cord-350019-4nlbu54e	323	57	60	60	CD
cord-350019-4nlbu54e	323	58	,	,	,
cord-350019-4nlbu54e	323	59	210	210	CD
cord-350019-4nlbu54e	323	60	]	]	-RRB-
cord-350019-4nlbu54e	323	61	.	.	.
cord-350019-4nlbu54e	324	1	In	in	IN
cord-350019-4nlbu54e	324	2	the	the	DT
cord-350019-4nlbu54e	324	3	cytosol	cytosol	NN
cord-350019-4nlbu54e	324	4	,	,	,
cord-350019-4nlbu54e	324	5	some	some	DT
cord-350019-4nlbu54e	324	6	lncRNAs	lncrnas	UH
cord-350019-4nlbu54e	324	7	have	have	VBP
cord-350019-4nlbu54e	324	8	been	be	VBN
cord-350019-4nlbu54e	324	9	shown	show	VBN
cord-350019-4nlbu54e	324	10	to	to	TO
cord-350019-4nlbu54e	324	11	interact	interact	VB
cord-350019-4nlbu54e	324	12	with	with	IN
cord-350019-4nlbu54e	324	13	RNAs	rna	NNS
cord-350019-4nlbu54e	324	14	and	and	CC
cord-350019-4nlbu54e	324	15	proteins	protein	NNS
cord-350019-4nlbu54e	324	16	to	to	TO
cord-350019-4nlbu54e	324	17	carry	carry	VB
cord-350019-4nlbu54e	324	18	out	out	RP
cord-350019-4nlbu54e	324	19	their	-PRON-	PRP$
cord-350019-4nlbu54e	324	20	molecular	molecular	JJ
cord-350019-4nlbu54e	324	21	functions	function	NNS
cord-350019-4nlbu54e	324	22	[	[	-LRB-
cord-350019-4nlbu54e	324	23	42	42	CD
cord-350019-4nlbu54e	324	24	,	,	,
cord-350019-4nlbu54e	324	25	79	79	CD
cord-350019-4nlbu54e	324	26	,	,	,
cord-350019-4nlbu54e	324	27	211	211	CD
cord-350019-4nlbu54e	324	28	,	,	,
cord-350019-4nlbu54e	324	29	212	212	CD
cord-350019-4nlbu54e	324	30	]	]	-RRB-
cord-350019-4nlbu54e	324	31	.	.	.
cord-350019-4nlbu54e	325	1	Cellular	cellular	JJ
cord-350019-4nlbu54e	325	2	localization	localization	NN
cord-350019-4nlbu54e	325	3	of	of	IN
cord-350019-4nlbu54e	325	4	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	325	5	can	can	MD
cord-350019-4nlbu54e	325	6	be	be	VB
cord-350019-4nlbu54e	325	7	predicted	predict	VBN
cord-350019-4nlbu54e	325	8	using	use	VBG
cord-350019-4nlbu54e	325	9	a	a	DT
cord-350019-4nlbu54e	325	10	publicly	publicly	RB
cord-350019-4nlbu54e	325	11	available	available	JJ
cord-350019-4nlbu54e	325	12	user	user	NN
cord-350019-4nlbu54e	325	13	-	-	HYPH
cord-350019-4nlbu54e	325	14	friendly	friendly	JJ
cord-350019-4nlbu54e	325	15	web	web	NN
cord-350019-4nlbu54e	325	16	server	server	NN
cord-350019-4nlbu54e	325	17	established	establish	VBN
cord-350019-4nlbu54e	325	18	at	at	IN
cord-350019-4nlbu54e	325	19	http://lin-group.cn/	http://lin-group.cn/	CD
cord-350019-4nlbu54e	325	20	server	server	NN
cord-350019-4nlbu54e	326	1	/iLoc	/iLoc	,
cord-350019-4nlbu54e	326	2	-	-	HYPH
cord-350019-4nlbu54e	326	3	LncRNA	LncRNA	NNP
cord-350019-4nlbu54e	326	4	[	[	-LRB-
cord-350019-4nlbu54e	326	5	213	213	CD
cord-350019-4nlbu54e	326	6	]	]	-RRB-
cord-350019-4nlbu54e	326	7	.	.	.
cord-350019-4nlbu54e	327	1	This	this	DT
cord-350019-4nlbu54e	327	2	can	can	MD
cord-350019-4nlbu54e	327	3	be	be	VB
cord-350019-4nlbu54e	327	4	the	the	DT
cord-350019-4nlbu54e	327	5	first	first	JJ
cord-350019-4nlbu54e	327	6	step	step	NN
cord-350019-4nlbu54e	327	7	by	by	IN
cord-350019-4nlbu54e	327	8	a	a	DT
cord-350019-4nlbu54e	327	9	researcher	researcher	NN
cord-350019-4nlbu54e	327	10	to	to	TO
cord-350019-4nlbu54e	327	11	attempt	attempt	VB
cord-350019-4nlbu54e	327	12	to	to	TO
cord-350019-4nlbu54e	327	13	predict	predict	VB
cord-350019-4nlbu54e	327	14	the	the	DT
cord-350019-4nlbu54e	327	15	localization	localization	NN
cord-350019-4nlbu54e	327	16	of	of	IN
cord-350019-4nlbu54e	327	17	your	-PRON-	PRP$
cord-350019-4nlbu54e	327	18	candidate	candidate	NN
cord-350019-4nlbu54e	327	19	based	base	VBN
cord-350019-4nlbu54e	327	20	off	off	IN
cord-350019-4nlbu54e	327	21	of	of	IN
cord-350019-4nlbu54e	327	22	its	-PRON-	PRP$
cord-350019-4nlbu54e	327	23	sequence	sequence	NN
cord-350019-4nlbu54e	327	24	.	.	.
cord-350019-4nlbu54e	328	1	iLoc	iLoc	NNP
cord-350019-4nlbu54e	328	2	-	-	HYPH
cord-350019-4nlbu54e	328	3	LncRNA	LncRNA	NNP
cord-350019-4nlbu54e	328	4	predicts	predict	VBZ
cord-350019-4nlbu54e	328	5	subcellular	subcellular	JJ
cord-350019-4nlbu54e	328	6	location	location	NN
cord-350019-4nlbu54e	328	7	of	of	IN
cord-350019-4nlbu54e	328	8	a	a	DT
cord-350019-4nlbu54e	328	9	lncRNA	lncrna	NN
cord-350019-4nlbu54e	328	10	by	by	IN
cord-350019-4nlbu54e	328	11	utilizing	utilize	VBG
cord-350019-4nlbu54e	328	12	the	the	DT
cord-350019-4nlbu54e	328	13	8-tuple	8-tuple	CD
cord-350019-4nlbu54e	328	14	nucleotide	nucleotide	NN
cord-350019-4nlbu54e	328	15	features	feature	NNS
cord-350019-4nlbu54e	328	16	into	into	IN
cord-350019-4nlbu54e	328	17	the	the	DT
cord-350019-4nlbu54e	328	18	general	general	JJ
cord-350019-4nlbu54e	328	19	PseKNC	PseKNC	NNPS
cord-350019-4nlbu54e	328	20	(	(	-LRB-
cord-350019-4nlbu54e	328	21	Pseudo	Pseudo	NNP
cord-350019-4nlbu54e	328	22	K	K	NNP
cord-350019-4nlbu54e	328	23	-	-	HYPH
cord-350019-4nlbu54e	328	24	tuple	tuple	NN
cord-350019-4nlbu54e	328	25	Nucleotide	Nucleotide	NNP
cord-350019-4nlbu54e	328	26	Composition	Composition	NNP
cord-350019-4nlbu54e	328	27	)	)	-RRB-
cord-350019-4nlbu54e	328	28	and	and	CC
cord-350019-4nlbu54e	328	29	rigorous	rigorous	JJ
cord-350019-4nlbu54e	328	30	tests	test	NNS
cord-350019-4nlbu54e	328	31	show	show	VBP
cord-350019-4nlbu54e	328	32	the	the	DT
cord-350019-4nlbu54e	328	33	overall	overall	JJ
cord-350019-4nlbu54e	328	34	accuracy	accuracy	NN
cord-350019-4nlbu54e	328	35	achieved	achieve	VBN
cord-350019-4nlbu54e	328	36	by	by	IN
cord-350019-4nlbu54e	328	37	the	the	DT
cord-350019-4nlbu54e	328	38	new	new	JJ
cord-350019-4nlbu54e	328	39	predictor	predictor	NN
cord-350019-4nlbu54e	328	40	is	be	VBZ
cord-350019-4nlbu54e	328	41	86.72	86.72	CD
cord-350019-4nlbu54e	328	42	%	%	NN
cord-350019-4nlbu54e	328	43	,	,	,
cord-350019-4nlbu54e	328	44	which	which	WDT
cord-350019-4nlbu54e	328	45	is	be	VBZ
cord-350019-4nlbu54e	328	46	over	over	IN
cord-350019-4nlbu54e	328	47	20	20	CD
cord-350019-4nlbu54e	328	48	%	%	NN
cord-350019-4nlbu54e	328	49	better	well	JJR
cord-350019-4nlbu54e	328	50	than	than	IN
cord-350019-4nlbu54e	328	51	previous	previous	JJ
cord-350019-4nlbu54e	328	52	algorithms	algorithm	NNS
cord-350019-4nlbu54e	328	53	[	[	-LRB-
cord-350019-4nlbu54e	328	54	213	213	CD
cord-350019-4nlbu54e	328	55	]	]	-RRB-
cord-350019-4nlbu54e	328	56	.	.	.
cord-350019-4nlbu54e	329	1	In	in	IN
cord-350019-4nlbu54e	329	2	addition	addition	NN
cord-350019-4nlbu54e	329	3	to	to	IN
cord-350019-4nlbu54e	329	4	prediction	prediction	NN
cord-350019-4nlbu54e	329	5	methods	method	NNS
cord-350019-4nlbu54e	329	6	,	,	,
cord-350019-4nlbu54e	329	7	there	there	EX
cord-350019-4nlbu54e	329	8	are	be	VBP
cord-350019-4nlbu54e	329	9	also	also	RB
cord-350019-4nlbu54e	329	10	publicly	publicly	RB
cord-350019-4nlbu54e	329	11	available	available	JJ
cord-350019-4nlbu54e	329	12	sequencing	sequencing	NN
cord-350019-4nlbu54e	329	13	datasets	dataset	NNS
cord-350019-4nlbu54e	329	14	that	that	WDT
cord-350019-4nlbu54e	329	15	have	have	VBP
cord-350019-4nlbu54e	329	16	performed	perform	VBN
cord-350019-4nlbu54e	329	17	RNA	RNA	NNP
cord-350019-4nlbu54e	329	18	sequencing	sequencing	NN
cord-350019-4nlbu54e	329	19	on	on	IN
cord-350019-4nlbu54e	329	20	fractionated	fractionated	JJ
cord-350019-4nlbu54e	329	21	cells	cell	NNS
cord-350019-4nlbu54e	329	22	.	.	.
cord-350019-4nlbu54e	330	1	Bhatt	Bhatt	NNP
cord-350019-4nlbu54e	330	2	et	et	NNP
cord-350019-4nlbu54e	330	3	al	al	NNP
cord-350019-4nlbu54e	330	4	.	.	.
cord-350019-4nlbu54e	331	1	utilized	utilize	VBN
cord-350019-4nlbu54e	331	2	murine	murine	JJ
cord-350019-4nlbu54e	331	3	bone	bone	NN
cord-350019-4nlbu54e	331	4	marrow	marrow	NN
cord-350019-4nlbu54e	331	5	derived	derive	VBN
cord-350019-4nlbu54e	331	6	macrophages	macrophage	NNS
cord-350019-4nlbu54e	331	7	,	,	,
cord-350019-4nlbu54e	331	8	with	with	IN
cord-350019-4nlbu54e	331	9	and	and	CC
cord-350019-4nlbu54e	331	10	without	without	IN
cord-350019-4nlbu54e	331	11	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	331	12	stimulation	stimulation	NN
cord-350019-4nlbu54e	331	13	,	,	,
cord-350019-4nlbu54e	331	14	and	and	CC
cord-350019-4nlbu54e	331	15	fractionated	fractionate	VBD
cord-350019-4nlbu54e	331	16	these	these	DT
cord-350019-4nlbu54e	331	17	cells	cell	NNS
cord-350019-4nlbu54e	331	18	into	into	IN
cord-350019-4nlbu54e	331	19	chromatin	chromatin	NN
cord-350019-4nlbu54e	331	20	,	,	,
cord-350019-4nlbu54e	331	21	nuclear	nuclear	JJ
cord-350019-4nlbu54e	331	22	,	,	,
cord-350019-4nlbu54e	331	23	and	and	CC
cord-350019-4nlbu54e	331	24	cytoplasmic	cytoplasmic	JJ
cord-350019-4nlbu54e	331	25	compartment	compartment	NN
cord-350019-4nlbu54e	331	26	to	to	TO
cord-350019-4nlbu54e	331	27	determine	determine	VB
cord-350019-4nlbu54e	331	28	RNA	RNA	NNP
cord-350019-4nlbu54e	331	29	localization	localization	NN
cord-350019-4nlbu54e	331	30	[	[	-LRB-
cord-350019-4nlbu54e	331	31	74	74	CD
cord-350019-4nlbu54e	331	32	]	]	-RRB-
cord-350019-4nlbu54e	331	33	.	.	.
cord-350019-4nlbu54e	332	1	This	this	DT
cord-350019-4nlbu54e	332	2	data	data	NN
cord-350019-4nlbu54e	332	3	set	set	NN
cord-350019-4nlbu54e	332	4	can	can	MD
cord-350019-4nlbu54e	332	5	now	now	RB
cord-350019-4nlbu54e	332	6	be	be	VB
cord-350019-4nlbu54e	332	7	utilized	utilize	VBN
cord-350019-4nlbu54e	332	8	to	to	TO
cord-350019-4nlbu54e	332	9	investigate	investigate	VB
cord-350019-4nlbu54e	332	10	the	the	DT
cord-350019-4nlbu54e	332	11	localization	localization	NN
cord-350019-4nlbu54e	332	12	of	of	IN
cord-350019-4nlbu54e	332	13	any	any	DT
cord-350019-4nlbu54e	332	14	murine	murine	JJ
cord-350019-4nlbu54e	332	15	candidate	candidate	NN
cord-350019-4nlbu54e	332	16	expressed	express	VBN
cord-350019-4nlbu54e	332	17	in	in	IN
cord-350019-4nlbu54e	332	18	macrophages	macrophage	NNS
cord-350019-4nlbu54e	332	19	.	.	.
cord-350019-4nlbu54e	333	1	A	a	DT
cord-350019-4nlbu54e	333	2	recent	recent	JJ
cord-350019-4nlbu54e	333	3	study	study	NN
cord-350019-4nlbu54e	333	4	took	take	VBD
cord-350019-4nlbu54e	333	5	this	this	DT
cord-350019-4nlbu54e	333	6	question	question	NN
cord-350019-4nlbu54e	333	7	a	a	DT
cord-350019-4nlbu54e	333	8	step	step	NN
cord-350019-4nlbu54e	333	9	further	far	RBR
cord-350019-4nlbu54e	333	10	by	by	IN
cord-350019-4nlbu54e	333	11	performing	perform	VBG
cord-350019-4nlbu54e	333	12	RNA	RNA	NNP
cord-350019-4nlbu54e	333	13	sequencing	sequencing	NN
cord-350019-4nlbu54e	333	14	on	on	IN
cord-350019-4nlbu54e	333	15	nine	nine	CD
cord-350019-4nlbu54e	333	16	separate	separate	JJ
cord-350019-4nlbu54e	333	17	locations	location	NNS
cord-350019-4nlbu54e	333	18	with	with	IN
cord-350019-4nlbu54e	333	19	a	a	DT
cord-350019-4nlbu54e	333	20	cell	cell	NN
cord-350019-4nlbu54e	333	21	including	include	VBG
cord-350019-4nlbu54e	333	22	:	:	:
cord-350019-4nlbu54e	333	23	nucleus	nucleus	NN
cord-350019-4nlbu54e	333	24	,	,	,
cord-350019-4nlbu54e	333	25	nucleolus	nucleolus	NN
cord-350019-4nlbu54e	333	26	,	,	,
cord-350019-4nlbu54e	333	27	nuclear	nuclear	JJ
cord-350019-4nlbu54e	333	28	lamina	lamina	NN
cord-350019-4nlbu54e	333	29	,	,	,
cord-350019-4nlbu54e	333	30	nuclear	nuclear	JJ
cord-350019-4nlbu54e	333	31	pore	pore	NN
cord-350019-4nlbu54e	333	32	,	,	,
cord-350019-4nlbu54e	333	33	cytosol	cytosol	NN
cord-350019-4nlbu54e	333	34	,	,	,
cord-350019-4nlbu54e	333	35	endoplasmic	endoplasmic	NN
cord-350019-4nlbu54e	333	36	reticulum	reticulum	NN
cord-350019-4nlbu54e	333	37	membrane	membrane	NN
cord-350019-4nlbu54e	333	38	(	(	-LRB-
cord-350019-4nlbu54e	333	39	ERM	ERM	NNP
cord-350019-4nlbu54e	333	40	)	)	-RRB-
cord-350019-4nlbu54e	333	41	,	,	,
cord-350019-4nlbu54e	333	42	outer	outer	JJ
cord-350019-4nlbu54e	333	43	mitochondrial	mitochondrial	NN
cord-350019-4nlbu54e	333	44	membrane	membrane	NN
cord-350019-4nlbu54e	333	45	(	(	-LRB-
cord-350019-4nlbu54e	333	46	OMM	OMM	NNP
cord-350019-4nlbu54e	333	47	)	)	-RRB-
cord-350019-4nlbu54e	333	48	,	,	,
cord-350019-4nlbu54e	333	49	mitochondrial	mitochondrial	JJ
cord-350019-4nlbu54e	333	50	matrix	matrix	NN
cord-350019-4nlbu54e	333	51	(	(	-LRB-
cord-350019-4nlbu54e	333	52	MITO	MITO	NNP
cord-350019-4nlbu54e	333	53	)	)	-RRB-
cord-350019-4nlbu54e	333	54	,	,	,
cord-350019-4nlbu54e	333	55	and	and	CC
cord-350019-4nlbu54e	333	56	endoplasmic	endoplasmic	NN
cord-350019-4nlbu54e	333	57	reticulum	reticulum	NN
cord-350019-4nlbu54e	333	58	lumen	lumen	NN
cord-350019-4nlbu54e	333	59	[	[	-LRB-
cord-350019-4nlbu54e	333	60	214	214	CD
cord-350019-4nlbu54e	333	61	]	]	-RRB-
cord-350019-4nlbu54e	333	62	.	.	.
cord-350019-4nlbu54e	334	1	This	this	DT
cord-350019-4nlbu54e	334	2	exciting	exciting	JJ
cord-350019-4nlbu54e	334	3	study	study	NN
cord-350019-4nlbu54e	334	4	utilized	utilize	VBD
cord-350019-4nlbu54e	334	5	an	an	DT
cord-350019-4nlbu54e	334	6	APEX	apex	JJ
cord-350019-4nlbu54e	334	7	-	-	HYPH
cord-350019-4nlbu54e	334	8	sequencing	sequencing	NN
cord-350019-4nlbu54e	334	9	method	method	NN
cord-350019-4nlbu54e	334	10	,	,	,
cord-350019-4nlbu54e	334	11	where	where	WRB
cord-350019-4nlbu54e	334	12	the	the	DT
cord-350019-4nlbu54e	334	13	peroxidase	peroxidase	NN
cord-350019-4nlbu54e	334	14	enzyme	enzyme	NN
cord-350019-4nlbu54e	334	15	APEX2	apex2	NN
cord-350019-4nlbu54e	334	16	was	be	VBD
cord-350019-4nlbu54e	334	17	localized	localize	VBN
cord-350019-4nlbu54e	334	18	to	to	IN
cord-350019-4nlbu54e	334	19	these	these	DT
cord-350019-4nlbu54e	334	20	nine	nine	CD
cord-350019-4nlbu54e	334	21	separate	separate	JJ
cord-350019-4nlbu54e	334	22	locations	location	NNS
cord-350019-4nlbu54e	334	23	in	in	IN
cord-350019-4nlbu54e	334	24	nine	nine	CD
cord-350019-4nlbu54e	334	25	separate	separate	JJ
cord-350019-4nlbu54e	334	26	Human	human	JJ
cord-350019-4nlbu54e	334	27	embryonic	embryonic	JJ
cord-350019-4nlbu54e	334	28	kidney	kidney	NN
cord-350019-4nlbu54e	334	29	(	(	-LRB-
cord-350019-4nlbu54e	334	30	HEK	HEK	NNP
cord-350019-4nlbu54e	334	31	)	)	-RRB-
cord-350019-4nlbu54e	334	32	293	293	CD
cord-350019-4nlbu54e	334	33	T	T	NNP
cord-350019-4nlbu54e	334	34	cell	cell	NN
cord-350019-4nlbu54e	334	35	lines	line	NNS
cord-350019-4nlbu54e	334	36	.	.	.
cord-350019-4nlbu54e	335	1	APEX2	APEX2	NNP
cord-350019-4nlbu54e	335	2	can	can	MD
cord-350019-4nlbu54e	335	3	biotinylate	biotinylate	VB
cord-350019-4nlbu54e	335	4	nearby	nearby	JJ
cord-350019-4nlbu54e	335	5	RNA	RNA	NNP
cord-350019-4nlbu54e	335	6	molecules	molecule	NNS
cord-350019-4nlbu54e	335	7	allowing	allow	VBG
cord-350019-4nlbu54e	335	8	for	for	IN
cord-350019-4nlbu54e	335	9	streptavidin	streptavidin	NN
cord-350019-4nlbu54e	335	10	-	-	HYPH
cord-350019-4nlbu54e	335	11	based	base	VBN
cord-350019-4nlbu54e	335	12	immunoprecipitation	immunoprecipitation	NN
cord-350019-4nlbu54e	335	13	and	and	CC
cord-350019-4nlbu54e	335	14	RNA	RNA	NNP
cord-350019-4nlbu54e	335	15	sequencing	sequencing	NN
cord-350019-4nlbu54e	335	16	.	.	.
cord-350019-4nlbu54e	336	1	The	the	DT
cord-350019-4nlbu54e	336	2	APEX	apex	JJ
cord-350019-4nlbu54e	336	3	-	-	HYPH
cord-350019-4nlbu54e	336	4	seq	seq	NN
cord-350019-4nlbu54e	336	5	datasets	dataset	NNS
cord-350019-4nlbu54e	336	6	will	will	MD
cord-350019-4nlbu54e	336	7	provide	provide	VB
cord-350019-4nlbu54e	336	8	a	a	DT
cord-350019-4nlbu54e	336	9	powerful	powerful	JJ
cord-350019-4nlbu54e	336	10	resource	resource	NN
cord-350019-4nlbu54e	336	11	for	for	IN
cord-350019-4nlbu54e	336	12	referencing	reference	VBG
cord-350019-4nlbu54e	336	13	localization	localization	NN
cord-350019-4nlbu54e	336	14	of	of	IN
cord-350019-4nlbu54e	336	15	specific	specific	JJ
cord-350019-4nlbu54e	336	16	lncRNA	lncrna	NN
cord-350019-4nlbu54e	336	17	candidates	candidate	NNS
cord-350019-4nlbu54e	336	18	that	that	WDT
cord-350019-4nlbu54e	336	19	are	be	VBP
cord-350019-4nlbu54e	336	20	expressed	express	VBN
cord-350019-4nlbu54e	336	21	in	in	IN
cord-350019-4nlbu54e	336	22	HEK293	HEK293	NNP
cord-350019-4nlbu54e	336	23	T	t	NN
cord-350019-4nlbu54e	336	24	cells	cell	NNS
cord-350019-4nlbu54e	336	25	[	[	-LRB-
cord-350019-4nlbu54e	336	26	214	214	CD
cord-350019-4nlbu54e	336	27	]	]	-RRB-
cord-350019-4nlbu54e	336	28	.	.	.
cord-350019-4nlbu54e	337	1	There	there	EX
cord-350019-4nlbu54e	337	2	are	be	VBP
cord-350019-4nlbu54e	337	3	a	a	DT
cord-350019-4nlbu54e	337	4	few	few	JJ
cord-350019-4nlbu54e	337	5	commonly	commonly	RB
cord-350019-4nlbu54e	337	6	used	use	VBN
cord-350019-4nlbu54e	337	7	experimental	experimental	JJ
cord-350019-4nlbu54e	337	8	approaches	approach	NNS
cord-350019-4nlbu54e	337	9	that	that	WDT
cord-350019-4nlbu54e	337	10	can	can	MD
cord-350019-4nlbu54e	337	11	be	be	VB
cord-350019-4nlbu54e	337	12	used	use	VBN
cord-350019-4nlbu54e	337	13	to	to	TO
cord-350019-4nlbu54e	337	14	validate	validate	VB
cord-350019-4nlbu54e	337	15	and	and	CC
cord-350019-4nlbu54e	337	16	determine	determine	VB
cord-350019-4nlbu54e	337	17	the	the	DT
cord-350019-4nlbu54e	337	18	localization	localization	NN
cord-350019-4nlbu54e	337	19	of	of	IN
cord-350019-4nlbu54e	337	20	a	a	DT
cord-350019-4nlbu54e	337	21	lncRNA	lncrna	NN
cord-350019-4nlbu54e	337	22	.	.	.
cord-350019-4nlbu54e	338	1	Subcellular	Subcellular	NNP
cord-350019-4nlbu54e	338	2	chromatin	chromatin	NN
cord-350019-4nlbu54e	338	3	,	,	,
cord-350019-4nlbu54e	338	4	nuclear	nuclear	JJ
cord-350019-4nlbu54e	338	5	and	and	CC
cord-350019-4nlbu54e	338	6	cytoplasmic	cytoplasmic	JJ
cord-350019-4nlbu54e	338	7	fractionations	fractionation	NNS
cord-350019-4nlbu54e	338	8	of	of	IN
cord-350019-4nlbu54e	338	9	any	any	DT
cord-350019-4nlbu54e	338	10	primary	primary	JJ
cord-350019-4nlbu54e	338	11	or	or	CC
cord-350019-4nlbu54e	338	12	immortalized	immortalize	VBN
cord-350019-4nlbu54e	338	13	cells	cell	NNS
cord-350019-4nlbu54e	338	14	can	can	MD
cord-350019-4nlbu54e	338	15	be	be	VB
cord-350019-4nlbu54e	338	16	prepared	prepare	VBN
cord-350019-4nlbu54e	338	17	using	use	VBG
cord-350019-4nlbu54e	338	18	previously	previously	RB
cord-350019-4nlbu54e	338	19	published	publish	VBN
cord-350019-4nlbu54e	338	20	procedures	procedure	NNS
cord-350019-4nlbu54e	338	21	[	[	-LRB-
cord-350019-4nlbu54e	338	22	74	74	CD
cord-350019-4nlbu54e	338	23	,	,	,
cord-350019-4nlbu54e	338	24	215	215	CD
cord-350019-4nlbu54e	338	25	]	]	-RRB-
cord-350019-4nlbu54e	338	26	,	,	,
cord-350019-4nlbu54e	338	27	followed	follow	VBN
cord-350019-4nlbu54e	338	28	by	by	IN
cord-350019-4nlbu54e	338	29	RNA	rna	NN
cord-350019-4nlbu54e	338	30	isolation	isolation	NN
cord-350019-4nlbu54e	338	31	and	and	CC
cord-350019-4nlbu54e	338	32	RT	rt	NN
cord-350019-4nlbu54e	338	33	-	-	HYPH
cord-350019-4nlbu54e	338	34	qPCR	qPCR	NNP
cord-350019-4nlbu54e	338	35	to	to	TO
cord-350019-4nlbu54e	338	36	assess	assess	VB
cord-350019-4nlbu54e	338	37	the	the	DT
cord-350019-4nlbu54e	338	38	localization	localization	NN
cord-350019-4nlbu54e	338	39	.	.	.
cord-350019-4nlbu54e	339	1	If	if	IN
cord-350019-4nlbu54e	339	2	additional	additional	JJ
cord-350019-4nlbu54e	339	3	compartmental	compartmental	JJ
cord-350019-4nlbu54e	339	4	fractionation	fractionation	NN
cord-350019-4nlbu54e	339	5	is	be	VBZ
cord-350019-4nlbu54e	339	6	desired	desire	VBN
cord-350019-4nlbu54e	339	7	other	other	JJ
cord-350019-4nlbu54e	339	8	compartments	compartment	NNS
cord-350019-4nlbu54e	339	9	can	can	MD
cord-350019-4nlbu54e	339	10	be	be	VB
cord-350019-4nlbu54e	339	11	enriched	enrich	VBN
cord-350019-4nlbu54e	339	12	,	,	,
cord-350019-4nlbu54e	339	13	such	such	JJ
cord-350019-4nlbu54e	339	14	as	as	IN
cord-350019-4nlbu54e	339	15	mitochondria	mitochondrion	NNS
cord-350019-4nlbu54e	339	16	[	[	-LRB-
cord-350019-4nlbu54e	339	17	216	216	CD
cord-350019-4nlbu54e	339	18	,	,	,
cord-350019-4nlbu54e	339	19	217	217	CD
cord-350019-4nlbu54e	339	20	]	]	-RRB-
cord-350019-4nlbu54e	339	21	.	.	.
cord-350019-4nlbu54e	340	1	Another	another	DT
cord-350019-4nlbu54e	340	2	standard	standard	JJ
cord-350019-4nlbu54e	340	3	gold	gold	NN
cord-350019-4nlbu54e	340	4	technique	technique	NN
cord-350019-4nlbu54e	340	5	is	be	VBZ
cord-350019-4nlbu54e	340	6	to	to	TO
cord-350019-4nlbu54e	340	7	visually	visually	RB
cord-350019-4nlbu54e	340	8	determine	determine	VB
cord-350019-4nlbu54e	340	9	cellular	cellular	JJ
cord-350019-4nlbu54e	340	10	localization	localization	NN
cord-350019-4nlbu54e	340	11	by	by	IN
cord-350019-4nlbu54e	340	12	RNA	RNA	NNP
cord-350019-4nlbu54e	340	13	FISH	FISH	NNP
cord-350019-4nlbu54e	340	14	[	[	-LRB-
cord-350019-4nlbu54e	340	15	42	42	CD
cord-350019-4nlbu54e	340	16	]	]	-RRB-
cord-350019-4nlbu54e	340	17	.	.	.
cord-350019-4nlbu54e	341	1	RNA	RNA	NNP
cord-350019-4nlbu54e	341	2	localization	localization	NN
cord-350019-4nlbu54e	341	3	can	can	MD
cord-350019-4nlbu54e	341	4	also	also	RB
cord-350019-4nlbu54e	341	5	be	be	VB
cord-350019-4nlbu54e	341	6	directly	directly	RB
cord-350019-4nlbu54e	341	7	visualized	visualize	VBN
cord-350019-4nlbu54e	341	8	by	by	IN
cord-350019-4nlbu54e	341	9	microscopy	microscopy	NNS
cord-350019-4nlbu54e	341	10	[	[	-LRB-
cord-350019-4nlbu54e	341	11	218	218	CD
cord-350019-4nlbu54e	341	12	]	]	-RRB-
cord-350019-4nlbu54e	341	13	.	.	.
cord-350019-4nlbu54e	342	1	SeqFISH	seqfish	NN
cord-350019-4nlbu54e	342	2	techniques	technique	NNS
cord-350019-4nlbu54e	342	3	have	have	VBP
cord-350019-4nlbu54e	342	4	recently	recently	RB
cord-350019-4nlbu54e	342	5	been	be	VBN
cord-350019-4nlbu54e	342	6	pioneered	pioneer	VBN
cord-350019-4nlbu54e	342	7	for	for	IN
cord-350019-4nlbu54e	342	8	imaging	image	VBG
cord-350019-4nlbu54e	342	9	thousands	thousand	NNS
cord-350019-4nlbu54e	342	10	of	of	IN
cord-350019-4nlbu54e	342	11	cellular	cellular	JJ
cord-350019-4nlbu54e	342	12	RNAs	rna	NNS
cord-350019-4nlbu54e	342	13	at	at	IN
cord-350019-4nlbu54e	342	14	once	once	RB
cord-350019-4nlbu54e	342	15	using	use	VBG
cord-350019-4nlbu54e	342	16	barcoded	barcode	VBN
cord-350019-4nlbu54e	342	17	oligonucleotides	oligonucleotide	NNS
cord-350019-4nlbu54e	342	18	[	[	-LRB-
cord-350019-4nlbu54e	342	19	219	219	CD
cord-350019-4nlbu54e	342	20	]	]	-RRB-
cord-350019-4nlbu54e	342	21	.	.	.
cord-350019-4nlbu54e	343	1	The	the	DT
cord-350019-4nlbu54e	343	2	drawbacks	drawback	NNS
cord-350019-4nlbu54e	343	3	of	of	IN
cord-350019-4nlbu54e	343	4	these	these	DT
cord-350019-4nlbu54e	343	5	in	in	IN
cord-350019-4nlbu54e	343	6	-	-	HYPH
cord-350019-4nlbu54e	343	7	situ	situ	NN
cord-350019-4nlbu54e	343	8	fluorescence	fluorescence	NN
cord-350019-4nlbu54e	343	9	hybridization	hybridization	NN
cord-350019-4nlbu54e	343	10	(	(	-LRB-
cord-350019-4nlbu54e	343	11	FISH	fish	NN
cord-350019-4nlbu54e	343	12	)	)	-RRB-
cord-350019-4nlbu54e	343	13	based	base	VBN
cord-350019-4nlbu54e	343	14	approaches	approach	NNS
cord-350019-4nlbu54e	343	15	,	,	,
cord-350019-4nlbu54e	343	16	however	however	RB
cord-350019-4nlbu54e	343	17	,	,	,
cord-350019-4nlbu54e	343	18	are	be	VBP
cord-350019-4nlbu54e	343	19	the	the	DT
cord-350019-4nlbu54e	343	20	need	need	NN
cord-350019-4nlbu54e	343	21	for	for	IN
cord-350019-4nlbu54e	343	22	cell	cell	NN
cord-350019-4nlbu54e	343	23	fixation	fixation	NN
cord-350019-4nlbu54e	343	24	and	and	CC
cord-350019-4nlbu54e	343	25	permeabilization	permeabilization	NN
cord-350019-4nlbu54e	343	26	,	,	,
cord-350019-4nlbu54e	343	27	which	which	WDT
cord-350019-4nlbu54e	343	28	can	can	MD
cord-350019-4nlbu54e	343	29	re	re	VB
cord-350019-4nlbu54e	343	30	-	-	VB
cord-350019-4nlbu54e	343	31	localize	localize	VB
cord-350019-4nlbu54e	343	32	or	or	CC
cord-350019-4nlbu54e	343	33	extract	extract	VB
cord-350019-4nlbu54e	343	34	cellular	cellular	JJ
cord-350019-4nlbu54e	343	35	components	component	NNS
cord-350019-4nlbu54e	343	36	[	[	-LRB-
cord-350019-4nlbu54e	343	37	220	220	CD
cord-350019-4nlbu54e	343	38	]	]	-RRB-
cord-350019-4nlbu54e	343	39	.	.	.
cord-350019-4nlbu54e	344	1	In	in	IN
cord-350019-4nlbu54e	344	2	addition	addition	NN
cord-350019-4nlbu54e	344	3	to	to	IN
cord-350019-4nlbu54e	344	4	the	the	DT
cord-350019-4nlbu54e	344	5	difficulty	difficulty	NN
cord-350019-4nlbu54e	344	6	of	of	IN
cord-350019-4nlbu54e	344	7	assigning	assign	VBG
cord-350019-4nlbu54e	344	8	RNAs	rna	NNS
cord-350019-4nlbu54e	344	9	to	to	IN
cord-350019-4nlbu54e	344	10	specific	specific	JJ
cord-350019-4nlbu54e	344	11	organelles	organelle	NNS
cord-350019-4nlbu54e	344	12	or	or	CC
cord-350019-4nlbu54e	344	13	cellular	cellular	JJ
cord-350019-4nlbu54e	344	14	landmarks	landmark	NNS
cord-350019-4nlbu54e	344	15	due	due	JJ
cord-350019-4nlbu54e	344	16	to	to	IN
cord-350019-4nlbu54e	344	17	spatial	spatial	JJ
cord-350019-4nlbu54e	344	18	resolution	resolution	NN
cord-350019-4nlbu54e	344	19	limits	limit	NNS
cord-350019-4nlbu54e	344	20	,	,	,
cord-350019-4nlbu54e	344	21	some	some	DT
cord-350019-4nlbu54e	344	22	of	of	IN
cord-350019-4nlbu54e	344	23	these	these	DT
cord-350019-4nlbu54e	344	24	difficulties	difficulty	NNS
cord-350019-4nlbu54e	344	25	can	can	MD
cord-350019-4nlbu54e	344	26	be	be	VB
cord-350019-4nlbu54e	344	27	overcome	overcome	VBN
cord-350019-4nlbu54e	344	28	with	with	IN
cord-350019-4nlbu54e	344	29	the	the	DT
cord-350019-4nlbu54e	344	30	addition	addition	NN
cord-350019-4nlbu54e	344	31	of	of	IN
cord-350019-4nlbu54e	344	32	stains	stain	NNS
cord-350019-4nlbu54e	344	33	for	for	IN
cord-350019-4nlbu54e	344	34	markers	marker	NNS
cord-350019-4nlbu54e	344	35	of	of	IN
cord-350019-4nlbu54e	344	36	specific	specific	JJ
cord-350019-4nlbu54e	344	37	organelles	organelle	NNS
cord-350019-4nlbu54e	344	38	.	.	.
cord-350019-4nlbu54e	345	1	Conventionally	conventionally	RB
cord-350019-4nlbu54e	345	2	,	,	,
cord-350019-4nlbu54e	345	3	lncRNAs	lncrnas	RB
cord-350019-4nlbu54e	345	4	display	display	VB
cord-350019-4nlbu54e	345	5	poor	poor	JJ
cord-350019-4nlbu54e	345	6	sequence	sequence	NN
cord-350019-4nlbu54e	345	7	conservation	conservation	NN
cord-350019-4nlbu54e	345	8	across	across	IN
cord-350019-4nlbu54e	345	9	species	specie	NNS
cord-350019-4nlbu54e	345	10	,	,	,
cord-350019-4nlbu54e	345	11	with	with	IN
cord-350019-4nlbu54e	345	12	the	the	DT
cord-350019-4nlbu54e	345	13	exception	exception	NN
cord-350019-4nlbu54e	345	14	of	of	IN
cord-350019-4nlbu54e	345	15	finite	finite	JJ
cord-350019-4nlbu54e	345	16	regions	region	NNS
cord-350019-4nlbu54e	345	17	of	of	IN
cord-350019-4nlbu54e	345	18	conserved	conserve	VBN
cord-350019-4nlbu54e	345	19	bases	basis	NNS
cord-350019-4nlbu54e	345	20	surrounded	surround	VBN
cord-350019-4nlbu54e	345	21	by	by	IN
cord-350019-4nlbu54e	345	22	large	large	JJ
cord-350019-4nlbu54e	345	23	seemingly	seemingly	RB
cord-350019-4nlbu54e	345	24	unconstrained	unconstrained	JJ
cord-350019-4nlbu54e	345	25	sequences	sequence	NNS
cord-350019-4nlbu54e	345	26	[	[	-LRB-
cord-350019-4nlbu54e	345	27	221	221	CD
cord-350019-4nlbu54e	345	28	]	]	-RRB-
cord-350019-4nlbu54e	345	29	.	.	.
cord-350019-4nlbu54e	346	1	While	while	IN
cord-350019-4nlbu54e	346	2	sequence	sequence	NN
cord-350019-4nlbu54e	346	3	conservation	conservation	NN
cord-350019-4nlbu54e	346	4	does	do	VBZ
cord-350019-4nlbu54e	346	5	not	not	RB
cord-350019-4nlbu54e	346	6	constrain	constrain	VB
cord-350019-4nlbu54e	346	7	lncRNA	lncrna	NN
cord-350019-4nlbu54e	346	8	genes	gene	NNS
cord-350019-4nlbu54e	346	9	,	,	,
cord-350019-4nlbu54e	346	10	lncRNA	lncrna	NN
cord-350019-4nlbu54e	346	11	function	function	NN
cord-350019-4nlbu54e	346	12	is	be	VBZ
cord-350019-4nlbu54e	346	13	found	find	VBN
cord-350019-4nlbu54e	346	14	to	to	TO
cord-350019-4nlbu54e	346	15	be	be	VB
cord-350019-4nlbu54e	346	16	conserved	conserve	VBN
cord-350019-4nlbu54e	346	17	across	across	IN
cord-350019-4nlbu54e	346	18	species	specie	NNS
cord-350019-4nlbu54e	346	19	when	when	WRB
cord-350019-4nlbu54e	346	20	identifying	identify	VBG
cord-350019-4nlbu54e	346	21	motifs	motif	NNS
cord-350019-4nlbu54e	346	22	or	or	CC
cord-350019-4nlbu54e	346	23	structure	structure	NN
cord-350019-4nlbu54e	346	24	.	.	.
cord-350019-4nlbu54e	347	1	A	a	DT
cord-350019-4nlbu54e	347	2	great	great	JJ
cord-350019-4nlbu54e	347	3	example	example	NN
cord-350019-4nlbu54e	347	4	of	of	IN
cord-350019-4nlbu54e	347	5	this	this	DT
cord-350019-4nlbu54e	347	6	phenomena	phenomena	NN
cord-350019-4nlbu54e	347	7	is	be	VBZ
cord-350019-4nlbu54e	347	8	represented	represent	VBN
cord-350019-4nlbu54e	347	9	in	in	IN
cord-350019-4nlbu54e	347	10	the	the	DT
cord-350019-4nlbu54e	347	11	study	study	NN
cord-350019-4nlbu54e	347	12	of	of	IN
cord-350019-4nlbu54e	347	13	human	human	NN
cord-350019-4nlbu54e	347	14	maternally	maternally	RB
cord-350019-4nlbu54e	347	15	expressed	express	VBN
cord-350019-4nlbu54e	347	16	gene	gene	NN
cord-350019-4nlbu54e	347	17	3	3	CD
cord-350019-4nlbu54e	347	18	(	(	-LRB-
cord-350019-4nlbu54e	347	19	MEG3	MEG3	NNP
cord-350019-4nlbu54e	347	20	)	)	-RRB-
cord-350019-4nlbu54e	347	21	,	,	,
cord-350019-4nlbu54e	347	22	which	which	WDT
cord-350019-4nlbu54e	347	23	utilized	utilize	VBD
cord-350019-4nlbu54e	347	24	the	the	DT
cord-350019-4nlbu54e	347	25	computer	computer	NN
cord-350019-4nlbu54e	347	26	program	program	NN
cord-350019-4nlbu54e	347	27	mfold	mfold	NN
cord-350019-4nlbu54e	347	28	and	and	CC
cord-350019-4nlbu54e	347	29	multiple	multiple	JJ
cord-350019-4nlbu54e	347	30	ex	ex	AFX
cord-350019-4nlbu54e	347	31	vivo	vivo	NN
cord-350019-4nlbu54e	347	32	and	and	CC
cord-350019-4nlbu54e	347	33	in	in	IN
cord-350019-4nlbu54e	347	34	vitro	vitro	FW
cord-350019-4nlbu54e	347	35	chemical	chemical	NN
cord-350019-4nlbu54e	347	36	probing	probe	VBG
cord-350019-4nlbu54e	347	37	techniques	technique	NNS
cord-350019-4nlbu54e	347	38	to	to	TO
cord-350019-4nlbu54e	347	39	identify	identify	VB
cord-350019-4nlbu54e	347	40	common	common	JJ
cord-350019-4nlbu54e	347	41	motifs	motif	NNS
cord-350019-4nlbu54e	347	42	critical	critical	JJ
cord-350019-4nlbu54e	347	43	for	for	IN
cord-350019-4nlbu54e	347	44	retained	retain	VBN
cord-350019-4nlbu54e	347	45	function	function	NN
cord-350019-4nlbu54e	347	46	in	in	IN
cord-350019-4nlbu54e	347	47	orangutan	orangutan	NN
cord-350019-4nlbu54e	347	48	,	,	,
cord-350019-4nlbu54e	347	49	rat	rat	NN
cord-350019-4nlbu54e	347	50	,	,	,
cord-350019-4nlbu54e	347	51	mouse	mouse	NN
cord-350019-4nlbu54e	347	52	and	and	CC
cord-350019-4nlbu54e	347	53	pig	pig	NN
cord-350019-4nlbu54e	347	54	[	[	-LRB-
cord-350019-4nlbu54e	347	55	222	222	CD
cord-350019-4nlbu54e	347	56	,	,	,
cord-350019-4nlbu54e	347	57	223	223	CD
cord-350019-4nlbu54e	347	58	]	]	-RRB-
cord-350019-4nlbu54e	347	59	.	.	.
cord-350019-4nlbu54e	348	1	Another	another	DT
cord-350019-4nlbu54e	348	2	study	study	NN
cord-350019-4nlbu54e	348	3	highlighting	highlight	VBG
cord-350019-4nlbu54e	348	4	the	the	DT
cord-350019-4nlbu54e	348	5	marsupial	marsupial	JJ
cord-350019-4nlbu54e	348	6	Rsx	Rsx	NNP
cord-350019-4nlbu54e	348	7	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	348	8	was	be	VBD
cord-350019-4nlbu54e	348	9	initially	initially	RB
cord-350019-4nlbu54e	348	10	found	find	VBN
cord-350019-4nlbu54e	348	11	to	to	TO
cord-350019-4nlbu54e	348	12	have	have	VB
cord-350019-4nlbu54e	348	13	no	no	DT
cord-350019-4nlbu54e	348	14	linear	linear	JJ
cord-350019-4nlbu54e	348	15	sequence	sequence	NN
cord-350019-4nlbu54e	348	16	similarity	similarity	NN
cord-350019-4nlbu54e	348	17	with	with	IN
cord-350019-4nlbu54e	348	18	the	the	DT
cord-350019-4nlbu54e	348	19	lncRNA	lncrna	NN
cord-350019-4nlbu54e	348	20	Xist	Xist	NNP
cord-350019-4nlbu54e	348	21	.	.	.
cord-350019-4nlbu54e	349	1	However	however	RB
cord-350019-4nlbu54e	349	2	,	,	,
cord-350019-4nlbu54e	349	3	it	-PRON-	PRP
cord-350019-4nlbu54e	349	4	shared	share	VBD
cord-350019-4nlbu54e	349	5	substantial	substantial	JJ
cord-350019-4nlbu54e	349	6	levels	level	NNS
cord-350019-4nlbu54e	349	7	of	of	IN
cord-350019-4nlbu54e	349	8	non	non	JJ
cord-350019-4nlbu54e	349	9	-	-	JJ
cord-350019-4nlbu54e	349	10	linear	linear	JJ
cord-350019-4nlbu54e	349	11	conservation	conservation	NN
cord-350019-4nlbu54e	349	12	within	within	IN
cord-350019-4nlbu54e	349	13	k	k	NNP
cord-350019-4nlbu54e	349	14	-	-	HYPH
cord-350019-4nlbu54e	349	15	mer	mer	NNP
cord-350019-4nlbu54e	349	16	repeats	repeat	VBZ
cord-350019-4nlbu54e	349	17	that	that	IN
cord-350019-4nlbu54e	349	18	share	share	NN
cord-350019-4nlbu54e	349	19	functionally	functionally	RB
cord-350019-4nlbu54e	349	20	analogous	analogous	JJ
cord-350019-4nlbu54e	349	21	protein	protein	NN
cord-350019-4nlbu54e	349	22	-	-	HYPH
cord-350019-4nlbu54e	349	23	binding	bind	VBG
cord-350019-4nlbu54e	349	24	domains	domain	NNS
cord-350019-4nlbu54e	349	25	[	[	-LRB-
cord-350019-4nlbu54e	349	26	224	224	CD
cord-350019-4nlbu54e	349	27	]	]	-RRB-
cord-350019-4nlbu54e	349	28	.	.	.
cord-350019-4nlbu54e	350	1	Publicly	publicly	RB
cord-350019-4nlbu54e	350	2	available	available	JJ
cord-350019-4nlbu54e	350	3	web	web	NN
cord-350019-4nlbu54e	350	4	servers	server	NNS
cord-350019-4nlbu54e	350	5	can	can	MD
cord-350019-4nlbu54e	350	6	be	be	VB
cord-350019-4nlbu54e	350	7	utilized	utilize	VBN
cord-350019-4nlbu54e	350	8	to	to	TO
cord-350019-4nlbu54e	350	9	determine	determine	VB
cord-350019-4nlbu54e	350	10	the	the	DT
cord-350019-4nlbu54e	350	11	RNA	RNA	NNP
cord-350019-4nlbu54e	350	12	structure	structure	NN
cord-350019-4nlbu54e	350	13	of	of	IN
cord-350019-4nlbu54e	350	14	a	a	DT
cord-350019-4nlbu54e	350	15	lncRNA	lncrna	NN
cord-350019-4nlbu54e	350	16	depending	depend	VBG
cord-350019-4nlbu54e	350	17	on	on	IN
cord-350019-4nlbu54e	350	18	the	the	DT
cord-350019-4nlbu54e	350	19	size	size	NN
cord-350019-4nlbu54e	350	20	.	.	.
cord-350019-4nlbu54e	351	1	The	the	DT
cord-350019-4nlbu54e	351	2	caveats	caveat	NNS
cord-350019-4nlbu54e	351	3	to	to	IN
cord-350019-4nlbu54e	351	4	these	these	DT
cord-350019-4nlbu54e	351	5	web	web	NN
cord-350019-4nlbu54e	351	6	servers	server	NNS
cord-350019-4nlbu54e	351	7	are	be	VBP
cord-350019-4nlbu54e	351	8	they	-PRON-	PRP
cord-350019-4nlbu54e	351	9	do	do	VBP
cord-350019-4nlbu54e	351	10	not	not	RB
cord-350019-4nlbu54e	351	11	work	work	VB
cord-350019-4nlbu54e	351	12	efficiently	efficiently	RB
cord-350019-4nlbu54e	351	13	with	with	IN
cord-350019-4nlbu54e	351	14	large	large	JJ
cord-350019-4nlbu54e	351	15	transcripts	transcript	NNS
cord-350019-4nlbu54e	351	16	.	.	.
cord-350019-4nlbu54e	352	1	To	to	TO
cord-350019-4nlbu54e	352	2	overcome	overcome	VB
cord-350019-4nlbu54e	352	3	this	this	DT
cord-350019-4nlbu54e	352	4	,	,	,
cord-350019-4nlbu54e	352	5	one	one	PRP
cord-350019-4nlbu54e	352	6	can	can	MD
cord-350019-4nlbu54e	352	7	attempt	attempt	VB
cord-350019-4nlbu54e	352	8	to	to	TO
cord-350019-4nlbu54e	352	9	identify	identify	VB
cord-350019-4nlbu54e	352	10	the	the	DT
cord-350019-4nlbu54e	352	11	critical	critical	JJ
cord-350019-4nlbu54e	352	12	sequence	sequence	NN
cord-350019-4nlbu54e	352	13	within	within	IN
cord-350019-4nlbu54e	352	14	the	the	DT
cord-350019-4nlbu54e	352	15	lncRNA	lncrna	NN
cord-350019-4nlbu54e	352	16	that	that	WDT
cord-350019-4nlbu54e	352	17	could	could	MD
cord-350019-4nlbu54e	352	18	be	be	VB
cord-350019-4nlbu54e	352	19	functional	functional	JJ
cord-350019-4nlbu54e	352	20	using	use	VBG
cord-350019-4nlbu54e	352	21	RIP	rip	NN
cord-350019-4nlbu54e	352	22	-	-	HYPH
cord-350019-4nlbu54e	352	23	sequencing	sequencing	NN
cord-350019-4nlbu54e	352	24	databases	database	NNS
cord-350019-4nlbu54e	352	25	,	,	,
cord-350019-4nlbu54e	352	26	which	which	WDT
cord-350019-4nlbu54e	352	27	allow	allow	VBP
cord-350019-4nlbu54e	352	28	you	-PRON-	PRP
cord-350019-4nlbu54e	352	29	to	to	TO
cord-350019-4nlbu54e	352	30	input	input	VB
cord-350019-4nlbu54e	352	31	a	a	DT
cord-350019-4nlbu54e	352	32	gene	gene	NN
cord-350019-4nlbu54e	352	33	ID	ID	NNP
cord-350019-4nlbu54e	352	34	to	to	TO
cord-350019-4nlbu54e	352	35	identify	identify	VB
cord-350019-4nlbu54e	352	36	possible	possible	JJ
cord-350019-4nlbu54e	352	37	RNA	RNA	NNP
cord-350019-4nlbu54e	352	38	binding	bind	VBG
cord-350019-4nlbu54e	352	39	proteins	protein	NNS
cord-350019-4nlbu54e	352	40	(	(	-LRB-
cord-350019-4nlbu54e	352	41	RBPs	RBPs	NNP
cord-350019-4nlbu54e	352	42	)	)	-RRB-
cord-350019-4nlbu54e	352	43	.	.	.
cord-350019-4nlbu54e	353	1	Additionally	additionally	RB
cord-350019-4nlbu54e	353	2	,	,	,
cord-350019-4nlbu54e	353	3	if	if	IN
cord-350019-4nlbu54e	353	4	a	a	DT
cord-350019-4nlbu54e	353	5	lncRNA	lncrna	NN
cord-350019-4nlbu54e	353	6	has	have	VBZ
cord-350019-4nlbu54e	353	7	already	already	RB
cord-350019-4nlbu54e	353	8	been	be	VBN
cord-350019-4nlbu54e	353	9	identified	identify	VBN
cord-350019-4nlbu54e	353	10	to	to	TO
cord-350019-4nlbu54e	353	11	bind	bind	VB
cord-350019-4nlbu54e	353	12	to	to	IN
cord-350019-4nlbu54e	353	13	a	a	DT
cord-350019-4nlbu54e	353	14	protein	protein	NN
cord-350019-4nlbu54e	353	15	(	(	-LRB-
cord-350019-4nlbu54e	353	16	s	s	NN
cord-350019-4nlbu54e	353	17	)	)	-RRB-
cord-350019-4nlbu54e	353	18	,	,	,
cord-350019-4nlbu54e	353	19	RIP	rip	NN
cord-350019-4nlbu54e	353	20	-	-	HYPH
cord-350019-4nlbu54e	353	21	sequencing	sequencing	NN
cord-350019-4nlbu54e	353	22	databases	database	NNS
cord-350019-4nlbu54e	353	23	can	can	MD
cord-350019-4nlbu54e	353	24	elucidate	elucidate	VB
cord-350019-4nlbu54e	353	25	the	the	DT
cord-350019-4nlbu54e	353	26	specific	specific	JJ
cord-350019-4nlbu54e	353	27	binding	bind	VBG
cord-350019-4nlbu54e	353	28	location(s	location(s	NNP
cord-350019-4nlbu54e	353	29	)	)	-RRB-
cord-350019-4nlbu54e	353	30	.	.	.
cord-350019-4nlbu54e	354	1	Knowing	know	VBG
cord-350019-4nlbu54e	354	2	the	the	DT
cord-350019-4nlbu54e	354	3	location	location	NN
cord-350019-4nlbu54e	354	4	of	of	IN
cord-350019-4nlbu54e	354	5	RNA	RNA	NNP
cord-350019-4nlbu54e	354	6	-	-	HYPH
cord-350019-4nlbu54e	354	7	protein	protein	NN
cord-350019-4nlbu54e	354	8	interaction	interaction	NN
cord-350019-4nlbu54e	354	9	narrows	narrow	VBZ
cord-350019-4nlbu54e	354	10	down	down	IN
cord-350019-4nlbu54e	354	11	the	the	DT
cord-350019-4nlbu54e	354	12	sequence	sequence	NN
cord-350019-4nlbu54e	354	13	input	input	NN
cord-350019-4nlbu54e	354	14	,	,	,
cord-350019-4nlbu54e	354	15	that	that	WDT
cord-350019-4nlbu54e	354	16	can	can	MD
cord-350019-4nlbu54e	354	17	be	be	VB
cord-350019-4nlbu54e	354	18	used	use	VBN
cord-350019-4nlbu54e	354	19	for	for	IN
cord-350019-4nlbu54e	354	20	many	many	JJ
cord-350019-4nlbu54e	354	21	web	web	NN
cord-350019-4nlbu54e	354	22	servers	server	NNS
cord-350019-4nlbu54e	354	23	,	,	,
cord-350019-4nlbu54e	354	24	which	which	WDT
cord-350019-4nlbu54e	354	25	could	could	MD
cord-350019-4nlbu54e	354	26	enhance	enhance	VB
cord-350019-4nlbu54e	354	27	the	the	DT
cord-350019-4nlbu54e	354	28	elucidation	elucidation	NN
cord-350019-4nlbu54e	354	29	of	of	IN
cord-350019-4nlbu54e	354	30	a	a	DT
cord-350019-4nlbu54e	354	31	predictive	predictive	JJ
cord-350019-4nlbu54e	354	32	structure	structure	NN
cord-350019-4nlbu54e	354	33	.	.	.
cord-350019-4nlbu54e	355	1	If	if	IN
cord-350019-4nlbu54e	355	2	there	there	EX
cord-350019-4nlbu54e	355	3	is	be	VBZ
cord-350019-4nlbu54e	355	4	no	no	DT
cord-350019-4nlbu54e	355	5	information	information	NN
cord-350019-4nlbu54e	355	6	about	about	IN
cord-350019-4nlbu54e	355	7	potential	potential	JJ
cord-350019-4nlbu54e	355	8	protein	protein	NN
cord-350019-4nlbu54e	355	9	binding	bind	VBG
cord-350019-4nlbu54e	355	10	partners	partner	NNS
cord-350019-4nlbu54e	355	11	,	,	,
cord-350019-4nlbu54e	355	12	then	then	RB
cord-350019-4nlbu54e	355	13	these	these	DT
cord-350019-4nlbu54e	355	14	RNA	RNA	NNP
cord-350019-4nlbu54e	355	15	structure	structure	NN
cord-350019-4nlbu54e	355	16	webservers	webserver	NNS
cord-350019-4nlbu54e	355	17	will	will	MD
cord-350019-4nlbu54e	355	18	be	be	VB
cord-350019-4nlbu54e	355	19	of	of	IN
cord-350019-4nlbu54e	355	20	little	little	JJ
cord-350019-4nlbu54e	355	21	use	use	NN
cord-350019-4nlbu54e	355	22	.	.	.
cord-350019-4nlbu54e	356	1	An	an	DT
cord-350019-4nlbu54e	356	2	alternative	alternative	JJ
cord-350019-4nlbu54e	356	3	approach	approach	NN
cord-350019-4nlbu54e	356	4	to	to	TO
cord-350019-4nlbu54e	356	5	further	further	RB
cord-350019-4nlbu54e	356	6	investigate	investigate	VB
cord-350019-4nlbu54e	356	7	structure	structure	NN
cord-350019-4nlbu54e	356	8	is	be	VBZ
cord-350019-4nlbu54e	356	9	to	to	TO
cord-350019-4nlbu54e	356	10	utilize	utilize	VB
cord-350019-4nlbu54e	356	11	bioinformatic	bioinformatic	JJ
cord-350019-4nlbu54e	356	12	tools	tool	NNS
cord-350019-4nlbu54e	356	13	which	which	WDT
cord-350019-4nlbu54e	356	14	now	now	RB
cord-350019-4nlbu54e	356	15	include	include	VBP
cord-350019-4nlbu54e	356	16	parameters	parameter	NNS
cord-350019-4nlbu54e	356	17	for	for	IN
cord-350019-4nlbu54e	356	18	covariation	covariation	NN
cord-350019-4nlbu54e	356	19	.	.	.
cord-350019-4nlbu54e	357	1	Covariation	covariation	NN
cord-350019-4nlbu54e	357	2	analysis	analysis	NN
cord-350019-4nlbu54e	357	3	identifies	identify	VBZ
cord-350019-4nlbu54e	357	4	the	the	DT
cord-350019-4nlbu54e	357	5	positions	position	NNS
cord-350019-4nlbu54e	357	6	in	in	IN
cord-350019-4nlbu54e	357	7	an	an	DT
cord-350019-4nlbu54e	357	8	RNA	RNA	NNP
cord-350019-4nlbu54e	357	9	molecule	molecule	NN
cord-350019-4nlbu54e	357	10	that	that	WDT
cord-350019-4nlbu54e	357	11	have	have	VBP
cord-350019-4nlbu54e	357	12	similar	similar	JJ
cord-350019-4nlbu54e	357	13	patterns	pattern	NNS
cord-350019-4nlbu54e	357	14	of	of	IN
cord-350019-4nlbu54e	357	15	variation	variation	NN
cord-350019-4nlbu54e	357	16	and	and	CC
cord-350019-4nlbu54e	357	17	the	the	DT
cord-350019-4nlbu54e	357	18	purpose	purpose	NN
cord-350019-4nlbu54e	357	19	of	of	IN
cord-350019-4nlbu54e	357	20	this	this	DT
cord-350019-4nlbu54e	357	21	covariance	covariance	NN
cord-350019-4nlbu54e	357	22	is	be	VBZ
cord-350019-4nlbu54e	357	23	due	due	JJ
cord-350019-4nlbu54e	357	24	to	to	IN
cord-350019-4nlbu54e	357	25	structural	structural	JJ
cord-350019-4nlbu54e	357	26	constraints	constraint	NNS
cord-350019-4nlbu54e	357	27	initially	initially	RB
cord-350019-4nlbu54e	357	28	shown	show	VBN
cord-350019-4nlbu54e	357	29	for	for	IN
cord-350019-4nlbu54e	357	30	ribosomal	ribosomal	JJ
cord-350019-4nlbu54e	357	31	RNA	RNA	NNP
cord-350019-4nlbu54e	357	32	[	[	-LRB-
cord-350019-4nlbu54e	357	33	225	225	CD
cord-350019-4nlbu54e	357	34	]	]	-RRB-
cord-350019-4nlbu54e	357	35	and	and	CC
cord-350019-4nlbu54e	357	36	now	now	RB
cord-350019-4nlbu54e	357	37	also	also	RB
cord-350019-4nlbu54e	357	38	for	for	IN
cord-350019-4nlbu54e	357	39	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	357	40	[	[	-LRB-
cord-350019-4nlbu54e	357	41	123	123	CD
cord-350019-4nlbu54e	357	42	,	,	,
cord-350019-4nlbu54e	357	43	226	226	CD
cord-350019-4nlbu54e	357	44	]	]	-RRB-
cord-350019-4nlbu54e	357	45	.	.	.
cord-350019-4nlbu54e	358	1	This	this	DT
cord-350019-4nlbu54e	358	2	study	study	NN
cord-350019-4nlbu54e	358	3	predicts	predict	VBZ
cord-350019-4nlbu54e	358	4	structures	structure	NNS
cord-350019-4nlbu54e	358	5	for	for	IN
cord-350019-4nlbu54e	358	6	MALAT1	malat1	NN
cord-350019-4nlbu54e	358	7	,	,	,
cord-350019-4nlbu54e	358	8	using	use	VBG
cord-350019-4nlbu54e	358	9	over	over	IN
cord-350019-4nlbu54e	358	10	130	130	CD
cord-350019-4nlbu54e	358	11	vertebrate	vertebrate	JJ
cord-350019-4nlbu54e	358	12	sequences	sequence	NNS
cord-350019-4nlbu54e	358	13	,	,	,
cord-350019-4nlbu54e	358	14	as	as	RB
cord-350019-4nlbu54e	358	15	well	well	RB
cord-350019-4nlbu54e	358	16	as	as	IN
cord-350019-4nlbu54e	358	17	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	358	18	RepA	RepA	NNP
cord-350019-4nlbu54e	358	19	and	and	CC
cord-350019-4nlbu54e	358	20	HOTAIR	HOTAIR	NNP
cord-350019-4nlbu54e	358	21	[	[	-LRB-
cord-350019-4nlbu54e	358	22	227	227	CD
cord-350019-4nlbu54e	358	23	]	]	-RRB-
cord-350019-4nlbu54e	358	24	.	.	.
cord-350019-4nlbu54e	359	1	These	these	DT
cord-350019-4nlbu54e	359	2	powerful	powerful	JJ
cord-350019-4nlbu54e	359	3	tools	tool	NNS
cord-350019-4nlbu54e	359	4	allow	allow	VBP
cord-350019-4nlbu54e	359	5	scientists	scientist	NNS
cord-350019-4nlbu54e	359	6	to	to	TO
cord-350019-4nlbu54e	359	7	predict	predict	VB
cord-350019-4nlbu54e	359	8	structures	structure	NNS
cord-350019-4nlbu54e	359	9	in	in	IN
cord-350019-4nlbu54e	359	10	an	an	DT
cord-350019-4nlbu54e	359	11	RNA	RNA	NNP
cord-350019-4nlbu54e	359	12	molecule	molecule	NN
cord-350019-4nlbu54e	359	13	based	base	VBN
cord-350019-4nlbu54e	359	14	on	on	IN
cord-350019-4nlbu54e	359	15	covariance	covariance	NN
cord-350019-4nlbu54e	359	16	,	,	,
cord-350019-4nlbu54e	359	17	which	which	WDT
cord-350019-4nlbu54e	359	18	in	in	IN
cord-350019-4nlbu54e	359	19	turn	turn	NN
cord-350019-4nlbu54e	359	20	drive	drive	VBP
cord-350019-4nlbu54e	359	21	the	the	DT
cord-350019-4nlbu54e	359	22	next	next	JJ
cord-350019-4nlbu54e	359	23	steps	step	NNS
cord-350019-4nlbu54e	359	24	of	of	IN
cord-350019-4nlbu54e	359	25	experimentally	experimentally	RB
cord-350019-4nlbu54e	359	26	validating	validate	VBG
cord-350019-4nlbu54e	359	27	these	these	DT
cord-350019-4nlbu54e	359	28	findings	finding	NNS
cord-350019-4nlbu54e	359	29	.	.	.
cord-350019-4nlbu54e	360	1	Fortunately	fortunately	RB
cord-350019-4nlbu54e	360	2	,	,	,
cord-350019-4nlbu54e	360	3	there	there	EX
cord-350019-4nlbu54e	360	4	are	be	VBP
cord-350019-4nlbu54e	360	5	several	several	JJ
cord-350019-4nlbu54e	360	6	in	in	IN
cord-350019-4nlbu54e	360	7	vitro	vitro	FW
cord-350019-4nlbu54e	360	8	and	and	CC
cord-350019-4nlbu54e	360	9	in	in	IN
cord-350019-4nlbu54e	360	10	vivo	vivo	NN
cord-350019-4nlbu54e	360	11	experimental	experimental	JJ
cord-350019-4nlbu54e	360	12	techniques	technique	NNS
cord-350019-4nlbu54e	360	13	used	use	VBN
cord-350019-4nlbu54e	360	14	to	to	TO
cord-350019-4nlbu54e	360	15	assess	assess	VB
cord-350019-4nlbu54e	360	16	RNA	RNA	NNP
cord-350019-4nlbu54e	360	17	structure	structure	NN
cord-350019-4nlbu54e	360	18	for	for	IN
cord-350019-4nlbu54e	360	19	any	any	DT
cord-350019-4nlbu54e	360	20	size	size	NN
cord-350019-4nlbu54e	360	21	,	,	,
cord-350019-4nlbu54e	360	22	even	even	RB
cord-350019-4nlbu54e	360	23	up	up	IN
cord-350019-4nlbu54e	360	24	to	to	TO
cord-350019-4nlbu54e	360	25	17,000	17,000	CD
cord-350019-4nlbu54e	360	26	nt	nt	RB
cord-350019-4nlbu54e	360	27	(	(	-LRB-
cord-350019-4nlbu54e	360	28	XIST	XIST	NNP
cord-350019-4nlbu54e	360	29	)	)	-RRB-
cord-350019-4nlbu54e	360	30	.	.	.
cord-350019-4nlbu54e	361	1	Dimethyl	dimethyl	NN
cord-350019-4nlbu54e	361	2	sulfate	sulfate	NN
cord-350019-4nlbu54e	361	3	(	(	-LRB-
cord-350019-4nlbu54e	361	4	DMS	DMS	NNP
cord-350019-4nlbu54e	361	5	)	)	-RRB-
cord-350019-4nlbu54e	361	6	probing	probing	NN
cord-350019-4nlbu54e	361	7	uses	use	VBZ
cord-350019-4nlbu54e	361	8	a	a	DT
cord-350019-4nlbu54e	361	9	base	base	NN
cord-350019-4nlbu54e	361	10	-	-	HYPH
cord-350019-4nlbu54e	361	11	specific	specific	JJ
cord-350019-4nlbu54e	361	12	reagent	reagent	NN
cord-350019-4nlbu54e	361	13	that	that	WDT
cord-350019-4nlbu54e	361	14	can	can	MD
cord-350019-4nlbu54e	361	15	bind	bind	VB
cord-350019-4nlbu54e	361	16	and	and	CC
cord-350019-4nlbu54e	361	17	alter	alter	VB
cord-350019-4nlbu54e	361	18	the	the	DT
cord-350019-4nlbu54e	361	19	methylation	methylation	NN
cord-350019-4nlbu54e	361	20	state	state	NN
cord-350019-4nlbu54e	361	21	of	of	IN
cord-350019-4nlbu54e	361	22	unpaired	unpaired	JJ
cord-350019-4nlbu54e	361	23	adenosine	adenosine	NN
cord-350019-4nlbu54e	361	24	and	and	CC
cord-350019-4nlbu54e	361	25	cytosine	cytosine	NN
cord-350019-4nlbu54e	361	26	nucleotides	nucleotide	NNS
cord-350019-4nlbu54e	361	27	[	[	-LRB-
cord-350019-4nlbu54e	361	28	228	228	CD
cord-350019-4nlbu54e	361	29	,	,	,
cord-350019-4nlbu54e	361	30	229	229	CD
cord-350019-4nlbu54e	361	31	]	]	-RRB-
cord-350019-4nlbu54e	361	32	.	.	.
cord-350019-4nlbu54e	362	1	DMS	DMS	NNP
cord-350019-4nlbu54e	362	2	"	"	``
cord-350019-4nlbu54e	362	3	footprinting	footprinting	NN
cord-350019-4nlbu54e	362	4	"	"	''
cord-350019-4nlbu54e	362	5	is	be	VBZ
cord-350019-4nlbu54e	362	6	optimized	optimize	VBN
cord-350019-4nlbu54e	362	7	for	for	IN
cord-350019-4nlbu54e	362	8	structural	structural	JJ
cord-350019-4nlbu54e	362	9	analysis	analysis	NN
cord-350019-4nlbu54e	362	10	of	of	IN
cord-350019-4nlbu54e	362	11	RNA	RNA	NNP
cord-350019-4nlbu54e	362	12	.	.	.
cord-350019-4nlbu54e	363	1	Protein	protein	NN
cord-350019-4nlbu54e	363	2	binding	bind	VBG
cord-350019-4nlbu54e	363	3	to	to	IN
cord-350019-4nlbu54e	363	4	RNA	RNA	NNP
cord-350019-4nlbu54e	363	5	will	will	MD
cord-350019-4nlbu54e	363	6	generate	generate	VB
cord-350019-4nlbu54e	363	7	a	a	DT
cord-350019-4nlbu54e	363	8	"	"	``
cord-350019-4nlbu54e	363	9	footprint	footprint	NN
cord-350019-4nlbu54e	363	10	"	"	''
cord-350019-4nlbu54e	363	11	that	that	WDT
cord-350019-4nlbu54e	363	12	can	can	MD
cord-350019-4nlbu54e	363	13	be	be	VB
cord-350019-4nlbu54e	363	14	traced	trace	VBN
cord-350019-4nlbu54e	363	15	due	due	IN
cord-350019-4nlbu54e	363	16	to	to	IN
cord-350019-4nlbu54e	363	17	alterations	alteration	NNS
cord-350019-4nlbu54e	363	18	in	in	IN
cord-350019-4nlbu54e	363	19	the	the	DT
cord-350019-4nlbu54e	363	20	RNA	RNA	NNP
cord-350019-4nlbu54e	363	21	structure	structure	NN
cord-350019-4nlbu54e	363	22	.	.	.
cord-350019-4nlbu54e	364	1	The	the	DT
cord-350019-4nlbu54e	364	2	transcript	transcript	NN
cord-350019-4nlbu54e	364	3	size	size	NN
cord-350019-4nlbu54e	364	4	that	that	WDT
cord-350019-4nlbu54e	364	5	can	can	MD
cord-350019-4nlbu54e	364	6	be	be	VB
cord-350019-4nlbu54e	364	7	evaluated	evaluate	VBN
cord-350019-4nlbu54e	364	8	is	be	VBZ
cord-350019-4nlbu54e	364	9	rather	rather	RB
cord-350019-4nlbu54e	364	10	small	small	JJ
cord-350019-4nlbu54e	364	11	(	(	-LRB-
cord-350019-4nlbu54e	364	12	<	<	XX
cord-350019-4nlbu54e	364	13	500	500	CD
cord-350019-4nlbu54e	364	14	nt	nt	NN
cord-350019-4nlbu54e	364	15	)	)	-RRB-
cord-350019-4nlbu54e	364	16	but	but	CC
cord-350019-4nlbu54e	364	17	this	this	DT
cord-350019-4nlbu54e	364	18	method	method	NN
cord-350019-4nlbu54e	364	19	can	can	MD
cord-350019-4nlbu54e	364	20	be	be	VB
cord-350019-4nlbu54e	364	21	performed	perform	VBN
cord-350019-4nlbu54e	364	22	both	both	CC
cord-350019-4nlbu54e	364	23	in	in	IN
cord-350019-4nlbu54e	364	24	vitro	vitro	FW
cord-350019-4nlbu54e	364	25	and	and	CC
cord-350019-4nlbu54e	364	26	in	in	IN
cord-350019-4nlbu54e	364	27	vivo	vivo	NN
cord-350019-4nlbu54e	364	28	as	as	IN
cord-350019-4nlbu54e	364	29	DMS	DMS	NNP
cord-350019-4nlbu54e	364	30	can	can	MD
cord-350019-4nlbu54e	364	31	easily	easily	RB
cord-350019-4nlbu54e	364	32	penetrate	penetrate	VB
cord-350019-4nlbu54e	364	33	the	the	DT
cord-350019-4nlbu54e	364	34	cell	cell	NN
cord-350019-4nlbu54e	364	35	membrane	membrane	NN
cord-350019-4nlbu54e	364	36	,	,	,
cord-350019-4nlbu54e	364	37	shown	show	VBN
cord-350019-4nlbu54e	364	38	to	to	TO
cord-350019-4nlbu54e	364	39	work	work	VB
cord-350019-4nlbu54e	364	40	for	for	IN
cord-350019-4nlbu54e	364	41	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	364	42	from	from	IN
cord-350019-4nlbu54e	364	43	590	590	CD
cord-350019-4nlbu54e	364	44	nt	nt	NN
cord-350019-4nlbu54e	364	45	,	,	,
cord-350019-4nlbu54e	364	46	Braveheart	Braveheart	NNP
cord-350019-4nlbu54e	364	47	(	(	-LRB-
cord-350019-4nlbu54e	364	48	Brvht	Brvht	NNP
cord-350019-4nlbu54e	364	49	)	)	-RRB-
cord-350019-4nlbu54e	365	1	[	[	-LRB-
cord-350019-4nlbu54e	365	2	230	230	CD
cord-350019-4nlbu54e	365	3	]	]	-RRB-
cord-350019-4nlbu54e	365	4	.	.	.
cord-350019-4nlbu54e	366	1	Xue	Xue	NNP
cord-350019-4nlbu54e	366	2	et	et	NNP
cord-350019-4nlbu54e	366	3	al	al	NNP
cord-350019-4nlbu54e	366	4	.	.	.
cord-350019-4nlbu54e	367	1	utilized	utilize	VBN
cord-350019-4nlbu54e	367	2	DMS	DMS	NNP
cord-350019-4nlbu54e	367	3	and	and	CC
cord-350019-4nlbu54e	367	4	SHAPE	shape	NN
cord-350019-4nlbu54e	367	5	to	to	TO
cord-350019-4nlbu54e	367	6	determine	determine	VB
cord-350019-4nlbu54e	367	7	the	the	DT
cord-350019-4nlbu54e	367	8	multiple	multiple	JJ
cord-350019-4nlbu54e	367	9	smaller	small	JJR
cord-350019-4nlbu54e	367	10	order	order	NN
cord-350019-4nlbu54e	367	11	structures	structure	NNS
cord-350019-4nlbu54e	367	12	of	of	IN
cord-350019-4nlbu54e	367	13	Brvht	Brvht	NNP
cord-350019-4nlbu54e	367	14	,	,	,
cord-350019-4nlbu54e	367	15	including	include	VBG
cord-350019-4nlbu54e	367	16	an	an	DT
cord-350019-4nlbu54e	367	17	AGIL	AGIL	NNP
cord-350019-4nlbu54e	367	18	motif	motif	NN
cord-350019-4nlbu54e	367	19	and	and	CC
cord-350019-4nlbu54e	367	20	a	a	DT
cord-350019-4nlbu54e	367	21	90-degree	90-degree	JJ
cord-350019-4nlbu54e	367	22	turn	turn	NN
cord-350019-4nlbu54e	367	23	[	[	-LRB-
cord-350019-4nlbu54e	367	24	231	231	CD
cord-350019-4nlbu54e	367	25	]	]	-RRB-
cord-350019-4nlbu54e	367	26	.	.	.
cord-350019-4nlbu54e	368	1	This	this	DT
cord-350019-4nlbu54e	368	2	AGIL	AGIL	NNP
cord-350019-4nlbu54e	368	3	motif	motif	NN
cord-350019-4nlbu54e	368	4	is	be	VBZ
cord-350019-4nlbu54e	368	5	critical	critical	JJ
cord-350019-4nlbu54e	368	6	for	for	IN
cord-350019-4nlbu54e	368	7	transcription	transcription	NN
cord-350019-4nlbu54e	368	8	factor	factor	NN
cord-350019-4nlbu54e	368	9	binding	binding	NN
cord-350019-4nlbu54e	368	10	,	,	,
cord-350019-4nlbu54e	368	11	which	which	WDT
cord-350019-4nlbu54e	368	12	specifies	specify	VBZ
cord-350019-4nlbu54e	368	13	the	the	DT
cord-350019-4nlbu54e	368	14	cardiovascular	cardiovascular	JJ
cord-350019-4nlbu54e	368	15	lineage	lineage	NN
cord-350019-4nlbu54e	368	16	.	.	.
cord-350019-4nlbu54e	369	1	Targeting	Targeting	NNP
cord-350019-4nlbu54e	369	2	Structure	Structure	NNP
cord-350019-4nlbu54e	369	3	-	-	HYPH
cord-350019-4nlbu54e	369	4	Seq	Seq	NNP
cord-350019-4nlbu54e	369	5	relies	rely	VBZ
cord-350019-4nlbu54e	369	6	on	on	IN
cord-350019-4nlbu54e	369	7	RNA	RNA	NNP
cord-350019-4nlbu54e	369	8	methylation	methylation	NN
cord-350019-4nlbu54e	369	9	by	by	IN
cord-350019-4nlbu54e	369	10	DMA	DMA	NNP
cord-350019-4nlbu54e	369	11	being	be	VBG
cord-350019-4nlbu54e	369	12	performed	perform	VBN
cord-350019-4nlbu54e	369	13	in	in	IN
cord-350019-4nlbu54e	369	14	vivo	vivo	NNP
cord-350019-4nlbu54e	369	15	.	.	.
cord-350019-4nlbu54e	370	1	Using	use	VBG
cord-350019-4nlbu54e	370	2	this	this	DT
cord-350019-4nlbu54e	370	3	method	method	NN
cord-350019-4nlbu54e	370	4	,	,	,
cord-350019-4nlbu54e	370	5	structural	structural	JJ
cord-350019-4nlbu54e	370	6	models	model	NNS
cord-350019-4nlbu54e	370	7	of	of	IN
cord-350019-4nlbu54e	370	8	elements	element	NNS
cord-350019-4nlbu54e	370	9	within	within	IN
cord-350019-4nlbu54e	370	10	Xist	Xist	NNP
cord-350019-4nlbu54e	370	11	were	be	VBD
cord-350019-4nlbu54e	370	12	developed	develop	VBN
cord-350019-4nlbu54e	370	13	[	[	-LRB-
cord-350019-4nlbu54e	370	14	232	232	CD
cord-350019-4nlbu54e	370	15	]	]	-RRB-
cord-350019-4nlbu54e	370	16	.	.	.
cord-350019-4nlbu54e	371	1	SHAPE	shape	VB
cord-350019-4nlbu54e	371	2	(	(	-LRB-
cord-350019-4nlbu54e	371	3	selective	selective	JJ
cord-350019-4nlbu54e	371	4	2′hydroxyl	2′hydroxyl	CD
cord-350019-4nlbu54e	371	5	acylation	acylation	NN
cord-350019-4nlbu54e	371	6	by	by	IN
cord-350019-4nlbu54e	371	7	primer	primer	NN
cord-350019-4nlbu54e	371	8	extension	extension	NNP
cord-350019-4nlbu54e	371	9	)	)	-RRB-
cord-350019-4nlbu54e	371	10	,	,	,
cord-350019-4nlbu54e	371	11	as	as	RB
cord-350019-4nlbu54e	371	12	well	well	RB
cord-350019-4nlbu54e	371	13	as	as	IN
cord-350019-4nlbu54e	371	14	the	the	DT
cord-350019-4nlbu54e	371	15	modified	modify	VBN
cord-350019-4nlbu54e	371	16	SHAPE	shape	NN
cord-350019-4nlbu54e	371	17	-	-	HYPH
cord-350019-4nlbu54e	371	18	MaP	map	NN
cord-350019-4nlbu54e	371	19	[	[	-LRB-
cord-350019-4nlbu54e	371	20	233	233	CD
cord-350019-4nlbu54e	371	21	]	]	-RRB-
cord-350019-4nlbu54e	371	22	,	,	.
cord-350019-4nlbu54e	371	23	In	in	IN
cord-350019-4nlbu54e	371	24	-	-	HYPH
cord-350019-4nlbu54e	371	25	cell	cell	NN
cord-350019-4nlbu54e	371	26	SHAPE	shape	NN
cord-350019-4nlbu54e	371	27	-	-	HYPH
cord-350019-4nlbu54e	371	28	Seq	seq	NN
cord-350019-4nlbu54e	371	29	[	[	-LRB-
cord-350019-4nlbu54e	371	30	234	234	CD
cord-350019-4nlbu54e	371	31	]	]	-RRB-
cord-350019-4nlbu54e	371	32	and	and	CC
cord-350019-4nlbu54e	371	33	icSHAPE	icshape	NN
cord-350019-4nlbu54e	371	34	-	-	HYPH
cord-350019-4nlbu54e	371	35	seq	seq	NN
cord-350019-4nlbu54e	371	36	[	[	-LRB-
cord-350019-4nlbu54e	371	37	235	235	CD
cord-350019-4nlbu54e	371	38	]	]	-RRB-
cord-350019-4nlbu54e	371	39	,	,	,
cord-350019-4nlbu54e	371	40	can	can	MD
cord-350019-4nlbu54e	371	41	interrogate	interrogate	VB
cord-350019-4nlbu54e	371	42	the	the	DT
cord-350019-4nlbu54e	371	43	RNA	RNA	NNP
cord-350019-4nlbu54e	371	44	structure	structure	NN
cord-350019-4nlbu54e	371	45	both	both	CC
cord-350019-4nlbu54e	371	46	in	in	IN
cord-350019-4nlbu54e	371	47	vitro	vitro	FW
cord-350019-4nlbu54e	371	48	and	and	CC
cord-350019-4nlbu54e	371	49	in	in	IN
cord-350019-4nlbu54e	371	50	vivo	vivo	NN
cord-350019-4nlbu54e	371	51	using	use	VBG
cord-350019-4nlbu54e	371	52	the	the	DT
cord-350019-4nlbu54e	371	53	chemical	chemical	JJ
cord-350019-4nlbu54e	371	54	NMIA	NMIA	NNP
cord-350019-4nlbu54e	371	55	and	and	CC
cord-350019-4nlbu54e	371	56	its	-PRON-	PRP$
cord-350019-4nlbu54e	371	57	derivatives	derivative	NNS
cord-350019-4nlbu54e	371	58	to	to	TO
cord-350019-4nlbu54e	371	59	detect	detect	VB
cord-350019-4nlbu54e	371	60	flexible	flexible	JJ
cord-350019-4nlbu54e	371	61	regions	region	NNS
cord-350019-4nlbu54e	371	62	in	in	IN
cord-350019-4nlbu54e	371	63	RNA	RNA	NNP
cord-350019-4nlbu54e	371	64	secondary	secondary	JJ
cord-350019-4nlbu54e	371	65	structure	structure	NN
cord-350019-4nlbu54e	371	66	[	[	-LRB-
cord-350019-4nlbu54e	371	67	236	236	CD
cord-350019-4nlbu54e	371	68	,	,	,
cord-350019-4nlbu54e	371	69	237	237	CD
cord-350019-4nlbu54e	371	70	]	]	-RRB-
cord-350019-4nlbu54e	371	71	.	.	.
cord-350019-4nlbu54e	372	1	This	this	DT
cord-350019-4nlbu54e	372	2	method	method	NN
cord-350019-4nlbu54e	372	3	has	have	VBZ
cord-350019-4nlbu54e	372	4	been	be	VBN
cord-350019-4nlbu54e	372	5	proven	prove	VBN
cord-350019-4nlbu54e	372	6	valuable	valuable	JJ
cord-350019-4nlbu54e	372	7	for	for	IN
cord-350019-4nlbu54e	372	8	Xist	Xist	NNP
cord-350019-4nlbu54e	372	9	[	[	-LRB-
cord-350019-4nlbu54e	372	10	238	238	CD
cord-350019-4nlbu54e	372	11	]	]	-RRB-
cord-350019-4nlbu54e	372	12	,	,	.
cord-350019-4nlbu54e	373	1	RepA	RepA	NNP
cord-350019-4nlbu54e	373	2	[	[	-LRB-
cord-350019-4nlbu54e	373	3	239	239	CD
cord-350019-4nlbu54e	373	4	]	]	-RRB-
cord-350019-4nlbu54e	373	5	,	,	,
cord-350019-4nlbu54e	373	6	and	and	CC
cord-350019-4nlbu54e	373	7	Rox1/2	Rox1/2	NNP
cord-350019-4nlbu54e	373	8	[	[	-LRB-
cord-350019-4nlbu54e	373	9	240	240	CD
cord-350019-4nlbu54e	373	10	]	]	-RRB-
cord-350019-4nlbu54e	373	11	.	.	.
cord-350019-4nlbu54e	374	1	PARIS	PARIS	NNP
cord-350019-4nlbu54e	374	2	(	(	-LRB-
cord-350019-4nlbu54e	374	3	psoralen	psoralen	NNP
cord-350019-4nlbu54e	374	4	analysis	analysis	NN
cord-350019-4nlbu54e	374	5	of	of	IN
cord-350019-4nlbu54e	374	6	RNA	RNA	NNP
cord-350019-4nlbu54e	374	7	interactions	interaction	NNS
cord-350019-4nlbu54e	374	8	and	and	CC
cord-350019-4nlbu54e	374	9	structures	structure	NNS
cord-350019-4nlbu54e	374	10	)	)	-RRB-
cord-350019-4nlbu54e	374	11	was	be	VBD
cord-350019-4nlbu54e	374	12	recently	recently	RB
cord-350019-4nlbu54e	374	13	developed	develop	VBN
cord-350019-4nlbu54e	374	14	to	to	TO
cord-350019-4nlbu54e	374	15	determine	determine	VB
cord-350019-4nlbu54e	374	16	both	both	DT
cord-350019-4nlbu54e	374	17	RNA	RNA	NNP
cord-350019-4nlbu54e	374	18	structure	structure	NN
cord-350019-4nlbu54e	374	19	and	and	CC
cord-350019-4nlbu54e	374	20	interactions	interaction	NNS
cord-350019-4nlbu54e	374	21	in	in	IN
cord-350019-4nlbu54e	374	22	vivo	vivo	NN
cord-350019-4nlbu54e	374	23	[	[	-LRB-
cord-350019-4nlbu54e	374	24	241	241	CD
cord-350019-4nlbu54e	374	25	]	]	-RRB-
cord-350019-4nlbu54e	374	26	.	.	.
cord-350019-4nlbu54e	375	1	Using	use	VBG
cord-350019-4nlbu54e	375	2	this	this	DT
cord-350019-4nlbu54e	375	3	approach	approach	NN
cord-350019-4nlbu54e	375	4	,	,	,
cord-350019-4nlbu54e	375	5	a	a	DT
cord-350019-4nlbu54e	375	6	model	model	NN
cord-350019-4nlbu54e	375	7	for	for	IN
cord-350019-4nlbu54e	375	8	the	the	DT
cord-350019-4nlbu54e	375	9	higher	high	JJR
cord-350019-4nlbu54e	375	10	order	order	NN
cord-350019-4nlbu54e	375	11	structure	structure	NN
cord-350019-4nlbu54e	375	12	of	of	IN
cord-350019-4nlbu54e	375	13	Xist	Xist	NNP
cord-350019-4nlbu54e	375	14	was	be	VBD
cord-350019-4nlbu54e	375	15	interrogated	interrogate	VBN
cord-350019-4nlbu54e	375	16	[	[	-LRB-
cord-350019-4nlbu54e	375	17	241	241	CD
cord-350019-4nlbu54e	375	18	]	]	-RRB-
cord-350019-4nlbu54e	375	19	.	.	.
cord-350019-4nlbu54e	376	1	These	these	DT
cord-350019-4nlbu54e	376	2	approaches	approach	NNS
cord-350019-4nlbu54e	376	3	are	be	VBP
cord-350019-4nlbu54e	376	4	critical	critical	JJ
cord-350019-4nlbu54e	376	5	for	for	IN
cord-350019-4nlbu54e	376	6	identifying	identify	VBG
cord-350019-4nlbu54e	376	7	structural	structural	JJ
cord-350019-4nlbu54e	376	8	motifs	motif	NNS
cord-350019-4nlbu54e	376	9	and	and	CC
cord-350019-4nlbu54e	376	10	enhance	enhance	VB
cord-350019-4nlbu54e	376	11	conservation	conservation	NN
cord-350019-4nlbu54e	376	12	studies	study	NNS
cord-350019-4nlbu54e	376	13	,	,	,
cord-350019-4nlbu54e	376	14	as	as	RB
cord-350019-4nlbu54e	376	15	well	well	RB
cord-350019-4nlbu54e	376	16	as	as	IN
cord-350019-4nlbu54e	376	17	these	these	DT
cord-350019-4nlbu54e	376	18	identified	identify	VBN
cord-350019-4nlbu54e	376	19	elements	element	NNS
cord-350019-4nlbu54e	376	20	,	,	,
cord-350019-4nlbu54e	376	21	can	can	MD
cord-350019-4nlbu54e	376	22	be	be	VB
cord-350019-4nlbu54e	376	23	used	use	VBN
cord-350019-4nlbu54e	376	24	as	as	IN
cord-350019-4nlbu54e	376	25	novel	novel	JJ
cord-350019-4nlbu54e	376	26	targets	target	NNS
cord-350019-4nlbu54e	376	27	for	for	IN
cord-350019-4nlbu54e	376	28	further	further	JJ
cord-350019-4nlbu54e	376	29	exploration	exploration	NN
cord-350019-4nlbu54e	376	30	in	in	IN
cord-350019-4nlbu54e	376	31	precise	precise	JJ
cord-350019-4nlbu54e	376	32	intervention	intervention	NN
cord-350019-4nlbu54e	376	33	suitable	suitable	JJ
cord-350019-4nlbu54e	376	34	for	for	IN
cord-350019-4nlbu54e	376	35	therapeutic	therapeutic	JJ
cord-350019-4nlbu54e	376	36	applications	application	NNS
cord-350019-4nlbu54e	376	37	.	.	.
cord-350019-4nlbu54e	377	1	Alternative	alternative	JJ
cord-350019-4nlbu54e	377	2	splicing	splicing	NN
cord-350019-4nlbu54e	377	3	(	(	-LRB-
cord-350019-4nlbu54e	377	4	AS	as	IN
cord-350019-4nlbu54e	377	5	)	)	-RRB-
cord-350019-4nlbu54e	377	6	significantly	significantly	RB
cord-350019-4nlbu54e	377	7	impacts	impact	VBZ
cord-350019-4nlbu54e	377	8	the	the	DT
cord-350019-4nlbu54e	377	9	diversity	diversity	NN
cord-350019-4nlbu54e	377	10	of	of	IN
cord-350019-4nlbu54e	377	11	RNA	RNA	NNP
cord-350019-4nlbu54e	377	12	isoforms	isoform	NNS
cord-350019-4nlbu54e	377	13	produced	produce	VBN
cord-350019-4nlbu54e	377	14	,	,	,
cord-350019-4nlbu54e	377	15	which	which	WDT
cord-350019-4nlbu54e	377	16	in	in	IN
cord-350019-4nlbu54e	377	17	turn	turn	NN
cord-350019-4nlbu54e	377	18	impacts	impact	VBZ
cord-350019-4nlbu54e	377	19	the	the	DT
cord-350019-4nlbu54e	377	20	protein	protein	NN
cord-350019-4nlbu54e	377	21	isoforms	isoform	NNS
cord-350019-4nlbu54e	377	22	produced	produce	VBN
cord-350019-4nlbu54e	377	23	and	and	CC
cord-350019-4nlbu54e	377	24	can	can	MD
cord-350019-4nlbu54e	377	25	affect	affect	VB
cord-350019-4nlbu54e	377	26	many	many	JJ
cord-350019-4nlbu54e	377	27	aspects	aspect	NNS
cord-350019-4nlbu54e	377	28	of	of	IN
cord-350019-4nlbu54e	377	29	the	the	DT
cord-350019-4nlbu54e	377	30	protein	protein	NN
cord-350019-4nlbu54e	377	31	's	's	POS
cord-350019-4nlbu54e	377	32	biology	biology	NN
cord-350019-4nlbu54e	377	33	including	include	VBG
cord-350019-4nlbu54e	377	34	binding	bind	VBG
cord-350019-4nlbu54e	377	35	,	,	,
cord-350019-4nlbu54e	377	36	intracellular	intracellular	JJ
cord-350019-4nlbu54e	377	37	localization	localization	NN
cord-350019-4nlbu54e	377	38	,	,	,
cord-350019-4nlbu54e	377	39	enzymatic	enzymatic	JJ
cord-350019-4nlbu54e	377	40	activity	activity	NN
cord-350019-4nlbu54e	377	41	,	,	,
cord-350019-4nlbu54e	377	42	stability	stability	NN
cord-350019-4nlbu54e	377	43	,	,	,
cord-350019-4nlbu54e	377	44	posttranslational	posttranslational	JJ
cord-350019-4nlbu54e	377	45	modifications	modification	NNS
cord-350019-4nlbu54e	377	46	[	[	-LRB-
cord-350019-4nlbu54e	377	47	242	242	CD
cord-350019-4nlbu54e	377	48	]	]	-RRB-
cord-350019-4nlbu54e	377	49	.	.	.
cord-350019-4nlbu54e	378	1	AS	as	IN
cord-350019-4nlbu54e	378	2	also	also	RB
cord-350019-4nlbu54e	378	3	impacts	impact	VBZ
cord-350019-4nlbu54e	378	4	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	378	5	genes	gene	NNS
cord-350019-4nlbu54e	378	6	which	which	WDT
cord-350019-4nlbu54e	378	7	can	can	MD
cord-350019-4nlbu54e	378	8	have	have	VB
cord-350019-4nlbu54e	378	9	multiple	multiple	JJ
cord-350019-4nlbu54e	378	10	isoforms	isoform	NNS
cord-350019-4nlbu54e	378	11	depending	depend	VBG
cord-350019-4nlbu54e	378	12	on	on	IN
cord-350019-4nlbu54e	378	13	the	the	DT
cord-350019-4nlbu54e	378	14	cell	cell	NN
cord-350019-4nlbu54e	378	15	/	/	SYM
cord-350019-4nlbu54e	378	16	tissue	tissue	NN
cord-350019-4nlbu54e	378	17	,	,	,
cord-350019-4nlbu54e	378	18	age	age	NN
cord-350019-4nlbu54e	378	19	,	,	,
cord-350019-4nlbu54e	378	20	and	and	CC
cord-350019-4nlbu54e	378	21	disease	disease	NN
cord-350019-4nlbu54e	378	22	state	state	NN
cord-350019-4nlbu54e	378	23	[	[	-LRB-
cord-350019-4nlbu54e	378	24	243	243	CD
cord-350019-4nlbu54e	378	25	]	]	-RRB-
cord-350019-4nlbu54e	378	26	[	[	-LRB-
cord-350019-4nlbu54e	378	27	244	244	CD
cord-350019-4nlbu54e	378	28	]	]	-RRB-
cord-350019-4nlbu54e	378	29	[	[	-LRB-
cord-350019-4nlbu54e	378	30	245	245	CD
cord-350019-4nlbu54e	378	31	]	]	-RRB-
cord-350019-4nlbu54e	378	32	.	.	.
cord-350019-4nlbu54e	379	1	The	the	DT
cord-350019-4nlbu54e	379	2	UCSC	UCSC	NNP
cord-350019-4nlbu54e	379	3	genome	genome	NN
cord-350019-4nlbu54e	379	4	browser	browser	NN
cord-350019-4nlbu54e	379	5	[	[	-LRB-
cord-350019-4nlbu54e	379	6	125	125	CD
cord-350019-4nlbu54e	379	7	]	]	-RRB-
cord-350019-4nlbu54e	379	8	,	,	,
cord-350019-4nlbu54e	379	9	as	as	RB
cord-350019-4nlbu54e	379	10	well	well	RB
cord-350019-4nlbu54e	379	11	as	as	IN
cord-350019-4nlbu54e	379	12	NONCODEV5	NONCODEV5	VBN
cord-350019-4nlbu54e	379	13	[	[	-LRB-
cord-350019-4nlbu54e	379	14	92	92	CD
cord-350019-4nlbu54e	379	15	]	]	-RRB-
cord-350019-4nlbu54e	379	16	,	,	,
cord-350019-4nlbu54e	379	17	have	have	VBP
cord-350019-4nlbu54e	379	18	all	all	PDT
cord-350019-4nlbu54e	379	19	the	the	DT
cord-350019-4nlbu54e	379	20	annotated	annotated	JJ
cord-350019-4nlbu54e	379	21	isoform	isoform	NN
cord-350019-4nlbu54e	379	22	transcripts	transcript	NNS
cord-350019-4nlbu54e	379	23	for	for	IN
cord-350019-4nlbu54e	379	24	each	each	DT
cord-350019-4nlbu54e	379	25	gene	gene	NN
cord-350019-4nlbu54e	379	26	.	.	.
cord-350019-4nlbu54e	380	1	These	these	DT
cord-350019-4nlbu54e	380	2	tools	tool	NNS
cord-350019-4nlbu54e	380	3	will	will	MD
cord-350019-4nlbu54e	380	4	identify	identify	VB
cord-350019-4nlbu54e	380	5	annotated	annotate	VBN
cord-350019-4nlbu54e	380	6	transcript	transcript	NN
cord-350019-4nlbu54e	380	7	isoforms	isoform	NNS
cord-350019-4nlbu54e	380	8	while	while	IN
cord-350019-4nlbu54e	380	9	RNA	RNA	NNP
cord-350019-4nlbu54e	380	10	sequencing	sequencing	NN
cord-350019-4nlbu54e	380	11	will	will	MD
cord-350019-4nlbu54e	380	12	provide	provide	VB
cord-350019-4nlbu54e	380	13	information	information	NN
cord-350019-4nlbu54e	380	14	on	on	IN
cord-350019-4nlbu54e	380	15	which	which	WDT
cord-350019-4nlbu54e	380	16	of	of	IN
cord-350019-4nlbu54e	380	17	these	these	DT
cord-350019-4nlbu54e	380	18	splicing	splicing	NN
cord-350019-4nlbu54e	380	19	events	event	NNS
cord-350019-4nlbu54e	380	20	is	be	VBZ
cord-350019-4nlbu54e	380	21	utilized	utilize	VBN
cord-350019-4nlbu54e	380	22	in	in	IN
cord-350019-4nlbu54e	380	23	a	a	DT
cord-350019-4nlbu54e	380	24	given	give	VBN
cord-350019-4nlbu54e	380	25	cell	cell	NN
cord-350019-4nlbu54e	380	26	or	or	CC
cord-350019-4nlbu54e	380	27	biological	biological	JJ
cord-350019-4nlbu54e	380	28	state	state	NN
cord-350019-4nlbu54e	380	29	.	.	.
cord-350019-4nlbu54e	381	1	To	to	IN
cord-350019-4nlbu54e	381	2	date	date	NN
cord-350019-4nlbu54e	381	3	,	,	,
cord-350019-4nlbu54e	381	4	there	there	EX
cord-350019-4nlbu54e	381	5	have	have	VBP
cord-350019-4nlbu54e	381	6	only	only	RB
cord-350019-4nlbu54e	381	7	been	be	VBN
cord-350019-4nlbu54e	381	8	a	a	DT
cord-350019-4nlbu54e	381	9	small	small	JJ
cord-350019-4nlbu54e	381	10	number	number	NN
cord-350019-4nlbu54e	381	11	of	of	IN
cord-350019-4nlbu54e	381	12	papers	paper	NNS
cord-350019-4nlbu54e	381	13	focusing	focus	VBG
cord-350019-4nlbu54e	381	14	on	on	IN
cord-350019-4nlbu54e	381	15	the	the	DT
cord-350019-4nlbu54e	381	16	role	role	NN
cord-350019-4nlbu54e	381	17	that	that	IN
cord-350019-4nlbu54e	381	18	alternative	alternative	JJ
cord-350019-4nlbu54e	381	19	splicing	splicing	NN
cord-350019-4nlbu54e	381	20	plays	play	VBZ
cord-350019-4nlbu54e	381	21	in	in	IN
cord-350019-4nlbu54e	381	22	controlling	control	VBG
cord-350019-4nlbu54e	381	23	the	the	DT
cord-350019-4nlbu54e	381	24	immune	immune	JJ
cord-350019-4nlbu54e	381	25	system	system	NN
cord-350019-4nlbu54e	381	26	.	.	.
cord-350019-4nlbu54e	382	1	One	one	CD
cord-350019-4nlbu54e	382	2	recent	recent	JJ
cord-350019-4nlbu54e	382	3	global	global	JJ
cord-350019-4nlbu54e	382	4	study	study	NN
cord-350019-4nlbu54e	382	5	has	have	VBZ
cord-350019-4nlbu54e	382	6	shown	show	VBN
cord-350019-4nlbu54e	382	7	that	that	IN
cord-350019-4nlbu54e	382	8	widespread	widespread	JJ
cord-350019-4nlbu54e	382	9	shortening	shortening	NN
cord-350019-4nlbu54e	382	10	of	of	IN
cord-350019-4nlbu54e	382	11	3′	3′	CD
cord-350019-4nlbu54e	382	12	untranslated	untranslated	JJ
cord-350019-4nlbu54e	382	13	regions	region	NNS
cord-350019-4nlbu54e	382	14	and	and	CC
cord-350019-4nlbu54e	382	15	increased	increase	VBN
cord-350019-4nlbu54e	382	16	exon	exon	NN
cord-350019-4nlbu54e	382	17	inclusion	inclusion	NN
cord-350019-4nlbu54e	382	18	are	be	VBP
cord-350019-4nlbu54e	382	19	evolutionarily	evolutionarily	RB
cord-350019-4nlbu54e	382	20	conserved	conserve	VBN
cord-350019-4nlbu54e	382	21	features	feature	NNS
cord-350019-4nlbu54e	382	22	of	of	IN
cord-350019-4nlbu54e	382	23	innate	innate	JJ
cord-350019-4nlbu54e	382	24	immune	immune	JJ
cord-350019-4nlbu54e	382	25	responses	response	NNS
cord-350019-4nlbu54e	382	26	in	in	IN
cord-350019-4nlbu54e	382	27	primary	primary	JJ
cord-350019-4nlbu54e	382	28	human	human	JJ
cord-350019-4nlbu54e	382	29	macrophages	macrophage	NNS
cord-350019-4nlbu54e	382	30	following	follow	VBG
cord-350019-4nlbu54e	382	31	Listeria	Listeria	NNP
cord-350019-4nlbu54e	382	32	monocytogenes	monocytogene	NNS
cord-350019-4nlbu54e	382	33	and	and	CC
cord-350019-4nlbu54e	382	34	Salmonella	Salmonella	NNP
cord-350019-4nlbu54e	382	35	typhimurium	typhimurium	NN
cord-350019-4nlbu54e	382	36	infection	infection	NN
cord-350019-4nlbu54e	382	37	[	[	-LRB-
cord-350019-4nlbu54e	382	38	78	78	CD
cord-350019-4nlbu54e	382	39	]	]	-RRB-
cord-350019-4nlbu54e	382	40	.	.	.
cord-350019-4nlbu54e	383	1	This	this	DT
cord-350019-4nlbu54e	383	2	is	be	VBZ
cord-350019-4nlbu54e	383	3	a	a	DT
cord-350019-4nlbu54e	383	4	transformative	transformative	JJ
cord-350019-4nlbu54e	383	5	study	study	NN
cord-350019-4nlbu54e	383	6	for	for	IN
cord-350019-4nlbu54e	383	7	mRNAs	mrnas	CD
cord-350019-4nlbu54e	383	8	but	but	CC
cord-350019-4nlbu54e	383	9	can	can	MD
cord-350019-4nlbu54e	383	10	be	be	VB
cord-350019-4nlbu54e	383	11	reanalyzed	reanalyze	VBN
cord-350019-4nlbu54e	383	12	to	to	TO
cord-350019-4nlbu54e	383	13	examine	examine	VB
cord-350019-4nlbu54e	383	14	AS	as	IN
cord-350019-4nlbu54e	383	15	and	and	CC
cord-350019-4nlbu54e	383	16	possible	possible	JJ
cord-350019-4nlbu54e	383	17	contributions	contribution	NNS
cord-350019-4nlbu54e	383	18	from	from	IN
cord-350019-4nlbu54e	383	19	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	383	20	.	.	.
cord-350019-4nlbu54e	384	1	Publicly	publicly	RB
cord-350019-4nlbu54e	384	2	available	available	JJ
cord-350019-4nlbu54e	384	3	tools	tool	NNS
cord-350019-4nlbu54e	384	4	for	for	IN
cord-350019-4nlbu54e	384	5	tissue	tissue	NN
cord-350019-4nlbu54e	384	6	isoform	isoform	NN
cord-350019-4nlbu54e	384	7	expression	expression	NN
cord-350019-4nlbu54e	384	8	specificity	specificity	NN
cord-350019-4nlbu54e	384	9	is	be	VBZ
cord-350019-4nlbu54e	384	10	available	available	JJ
cord-350019-4nlbu54e	384	11	on	on	IN
cord-350019-4nlbu54e	384	12	GTEx	GTEx	NNS
cord-350019-4nlbu54e	384	13	[	[	-LRB-
cord-350019-4nlbu54e	384	14	97	97	CD
cord-350019-4nlbu54e	384	15	]	]	-RRB-
cord-350019-4nlbu54e	384	16	and	and	CC
cord-350019-4nlbu54e	384	17	XENA	XENA	NNP
cord-350019-4nlbu54e	384	18	[	[	-LRB-
cord-350019-4nlbu54e	384	19	98	98	CD
cord-350019-4nlbu54e	384	20	]	]	-RRB-
cord-350019-4nlbu54e	384	21	for	for	IN
cord-350019-4nlbu54e	384	22	human	human	JJ
cord-350019-4nlbu54e	384	23	genes	gene	NNS
cord-350019-4nlbu54e	384	24	.	.	.
cord-350019-4nlbu54e	385	1	Tabula	Tabula	NNP
cord-350019-4nlbu54e	385	2	Muris	Muris	NNP
cord-350019-4nlbu54e	385	3	[	[	-LRB-
cord-350019-4nlbu54e	385	4	100	100	CD
cord-350019-4nlbu54e	385	5	]	]	-RRB-
cord-350019-4nlbu54e	385	6	,	,	,
cord-350019-4nlbu54e	385	7	a	a	DT
cord-350019-4nlbu54e	385	8	murine	murine	JJ
cord-350019-4nlbu54e	385	9	specific	specific	JJ
cord-350019-4nlbu54e	385	10	dataset	dataset	NN
cord-350019-4nlbu54e	385	11	,	,	,
cord-350019-4nlbu54e	385	12	is	be	VBZ
cord-350019-4nlbu54e	385	13	now	now	RB
cord-350019-4nlbu54e	385	14	available	available	JJ
cord-350019-4nlbu54e	385	15	as	as	IN
cord-350019-4nlbu54e	385	16	a	a	DT
cord-350019-4nlbu54e	385	17	UCSC	UCSC	NNP
cord-350019-4nlbu54e	385	18	genome	genome	NN
cord-350019-4nlbu54e	385	19	browser	browser	NN
cord-350019-4nlbu54e	385	20	track	track	NN
cord-350019-4nlbu54e	385	21	on	on	IN
cord-350019-4nlbu54e	385	22	mm10	mm10	NNP
cord-350019-4nlbu54e	385	23	and	and	CC
cord-350019-4nlbu54e	385	24	can	can	MD
cord-350019-4nlbu54e	385	25	be	be	VB
cord-350019-4nlbu54e	385	26	used	use	VBN
cord-350019-4nlbu54e	385	27	to	to	TO
cord-350019-4nlbu54e	385	28	view	view	VB
cord-350019-4nlbu54e	385	29	cell	cell	NN
cord-350019-4nlbu54e	385	30	-	-	HYPH
cord-350019-4nlbu54e	385	31	type	type	NN
cord-350019-4nlbu54e	385	32	specific	specific	JJ
cord-350019-4nlbu54e	385	33	splicing	splicing	NN
cord-350019-4nlbu54e	385	34	events	event	NNS
cord-350019-4nlbu54e	385	35	and	and	CC
cord-350019-4nlbu54e	385	36	isoform	isoform	NN
cord-350019-4nlbu54e	385	37	expression	expression	NN
cord-350019-4nlbu54e	385	38	.	.	.
cord-350019-4nlbu54e	386	1	In	in	IN
cord-350019-4nlbu54e	386	2	order	order	NN
cord-350019-4nlbu54e	386	3	to	to	TO
cord-350019-4nlbu54e	386	4	identify	identify	VB
cord-350019-4nlbu54e	386	5	isoforms	isoform	NNS
cord-350019-4nlbu54e	386	6	in	in	IN
cord-350019-4nlbu54e	386	7	illumina	illumina	NNP
cord-350019-4nlbu54e	386	8	RNA	RNA	NNP
cord-350019-4nlbu54e	386	9	sequencing	sequencing	NN
cord-350019-4nlbu54e	386	10	datasets	dataset	NNS
cord-350019-4nlbu54e	386	11	,	,	,
cord-350019-4nlbu54e	386	12	several	several	JJ
cord-350019-4nlbu54e	386	13	tools	tool	NNS
cord-350019-4nlbu54e	386	14	can	can	MD
cord-350019-4nlbu54e	386	15	be	be	VB
cord-350019-4nlbu54e	386	16	utilized	utilize	VBN
cord-350019-4nlbu54e	386	17	.	.	.
cord-350019-4nlbu54e	387	1	MISO	MISO	NNP
cord-350019-4nlbu54e	387	2	(	(	-LRB-
cord-350019-4nlbu54e	387	3	Mixture	mixture	NN
cord-350019-4nlbu54e	387	4	of	of	IN
cord-350019-4nlbu54e	387	5	Isoforms	Isoforms	NNP
cord-350019-4nlbu54e	387	6	)	)	-RRB-
cord-350019-4nlbu54e	387	7	is	be	VBZ
cord-350019-4nlbu54e	387	8	software	software	NN
cord-350019-4nlbu54e	387	9	for	for	IN
cord-350019-4nlbu54e	387	10	a	a	DT
cord-350019-4nlbu54e	387	11	probabilistic	probabilistic	JJ
cord-350019-4nlbu54e	387	12	model	model	NN
cord-350019-4nlbu54e	387	13	for	for	IN
cord-350019-4nlbu54e	387	14	RNA	RNA	NNP
cord-350019-4nlbu54e	387	15	seq	seq	NN
cord-350019-4nlbu54e	387	16	will	will	MD
cord-350019-4nlbu54e	387	17	identify	identify	VB
cord-350019-4nlbu54e	387	18	specific	specific	JJ
cord-350019-4nlbu54e	387	19	the	the	DT
cord-350019-4nlbu54e	387	20	5′	5′	CD
cord-350019-4nlbu54e	387	21	splice	splice	NN
cord-350019-4nlbu54e	387	22	sites	site	NNS
cord-350019-4nlbu54e	387	23	used	use	VBN
cord-350019-4nlbu54e	387	24	for	for	IN
cord-350019-4nlbu54e	387	25	each	each	DT
cord-350019-4nlbu54e	387	26	isoform	isoform	NN
cord-350019-4nlbu54e	387	27	[	[	-LRB-
cord-350019-4nlbu54e	387	28	246	246	CD
cord-350019-4nlbu54e	387	29	]	]	-RRB-
cord-350019-4nlbu54e	387	30	.	.	.
cord-350019-4nlbu54e	388	1	Two	two	CD
cord-350019-4nlbu54e	388	2	other	other	JJ
cord-350019-4nlbu54e	388	3	tools	tool	NNS
cord-350019-4nlbu54e	388	4	highly	highly	RB
cord-350019-4nlbu54e	388	5	used	use	VBN
cord-350019-4nlbu54e	388	6	for	for	IN
cord-350019-4nlbu54e	388	7	splicing	splice	VBG
cord-350019-4nlbu54e	388	8	analysis	analysis	NN
cord-350019-4nlbu54e	388	9	are	be	VBP
cord-350019-4nlbu54e	388	10	JuncBASE	JuncBASE	.
cord-350019-4nlbu54e	388	11	[	[	-LRB-
cord-350019-4nlbu54e	388	12	247	247	CD
cord-350019-4nlbu54e	388	13	]	]	-RRB-
cord-350019-4nlbu54e	388	14	,	,	,
cord-350019-4nlbu54e	388	15	MAJIQ	MAJIQ	NNP
cord-350019-4nlbu54e	388	16	-	-	HYPH
cord-350019-4nlbu54e	388	17	SPEL	SPEL	NNP
cord-350019-4nlbu54e	388	18	[	[	-LRB-
cord-350019-4nlbu54e	388	19	248	248	CD
cord-350019-4nlbu54e	388	20	]	]	-RRB-
cord-350019-4nlbu54e	388	21	,	,	,
cord-350019-4nlbu54e	388	22	and	and	CC
cord-350019-4nlbu54e	388	23	DRIMSeq	DRIMSeq	NNP
cord-350019-4nlbu54e	388	24	[	[	-LRB-
cord-350019-4nlbu54e	388	25	249	249	CD
cord-350019-4nlbu54e	388	26	]	]	-RRB-
cord-350019-4nlbu54e	388	27	.	.	.
cord-350019-4nlbu54e	389	1	These	these	DT
cord-350019-4nlbu54e	389	2	tools	tool	NNS
cord-350019-4nlbu54e	389	3	can	can	MD
cord-350019-4nlbu54e	389	4	be	be	VB
cord-350019-4nlbu54e	389	5	used	use	VBN
cord-350019-4nlbu54e	389	6	to	to	TO
cord-350019-4nlbu54e	389	7	define	define	VB
cord-350019-4nlbu54e	389	8	if	if	IN
cord-350019-4nlbu54e	389	9	your	-PRON-	PRP$
cord-350019-4nlbu54e	389	10	candidate	candidate	NN
cord-350019-4nlbu54e	389	11	gene	gene	NN
cord-350019-4nlbu54e	389	12	undergoes	undergo	VBZ
cord-350019-4nlbu54e	389	13	any	any	DT
cord-350019-4nlbu54e	389	14	alternative	alternative	JJ
cord-350019-4nlbu54e	389	15	splicing	splicing	NN
cord-350019-4nlbu54e	389	16	(	(	-LRB-
cord-350019-4nlbu54e	389	17	alternative	alternative	JJ
cord-350019-4nlbu54e	389	18	start	start	NN
cord-350019-4nlbu54e	389	19	site	site	NN
cord-350019-4nlbu54e	389	20	,	,	,
cord-350019-4nlbu54e	389	21	exon	exon	NN
cord-350019-4nlbu54e	389	22	inclusion	inclusion	NN
cord-350019-4nlbu54e	389	23	/	/	SYM
cord-350019-4nlbu54e	389	24	exclusion	exclusion	NN
cord-350019-4nlbu54e	389	25	or	or	CC
cord-350019-4nlbu54e	389	26	alternative	alternative	JJ
cord-350019-4nlbu54e	389	27	last	last	JJ
cord-350019-4nlbu54e	389	28	exon	exon	NN
cord-350019-4nlbu54e	389	29	)	)	-RRB-
cord-350019-4nlbu54e	389	30	during	during	IN
cord-350019-4nlbu54e	389	31	a	a	DT
cord-350019-4nlbu54e	389	32	specific	specific	JJ
cord-350019-4nlbu54e	389	33	biological	biological	JJ
cord-350019-4nlbu54e	389	34	process	process	NN
cord-350019-4nlbu54e	389	35	for	for	IN
cord-350019-4nlbu54e	389	36	example	example	NN
cord-350019-4nlbu54e	389	37	following	follow	VBG
cord-350019-4nlbu54e	389	38	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	389	39	activation	activation	NN
cord-350019-4nlbu54e	389	40	.	.	.
cord-350019-4nlbu54e	390	1	These	these	DT
cord-350019-4nlbu54e	390	2	tools	tool	NNS
cord-350019-4nlbu54e	390	3	are	be	VBP
cord-350019-4nlbu54e	390	4	limited	limit	VBN
cord-350019-4nlbu54e	390	5	because	because	IN
cord-350019-4nlbu54e	390	6	of	of	IN
cord-350019-4nlbu54e	390	7	their	-PRON-	PRP$
cord-350019-4nlbu54e	390	8	dependence	dependence	NN
cord-350019-4nlbu54e	390	9	on	on	IN
cord-350019-4nlbu54e	390	10	a	a	DT
cord-350019-4nlbu54e	390	11	fully	fully	RB
cord-350019-4nlbu54e	390	12	annotated	annotate	VBN
cord-350019-4nlbu54e	390	13	transcriptomes	transcriptome	NNS
cord-350019-4nlbu54e	390	14	.	.	.
cord-350019-4nlbu54e	391	1	Therefore	therefore	RB
cord-350019-4nlbu54e	391	2	if	if	IN
cord-350019-4nlbu54e	391	3	a	a	DT
cord-350019-4nlbu54e	391	4	lncRNA	lncrna	NN
cord-350019-4nlbu54e	391	5	is	be	VBZ
cord-350019-4nlbu54e	391	6	unannotated	unannotate	VBN
cord-350019-4nlbu54e	391	7	or	or	CC
cord-350019-4nlbu54e	391	8	has	have	VBZ
cord-350019-4nlbu54e	391	9	unannotated	unannotate	VBN
cord-350019-4nlbu54e	391	10	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	391	11	isoforms	isoform	NNS
cord-350019-4nlbu54e	391	12	,	,	,
cord-350019-4nlbu54e	391	13	these	these	DT
cord-350019-4nlbu54e	391	14	events	event	NNS
cord-350019-4nlbu54e	391	15	will	will	MD
cord-350019-4nlbu54e	391	16	not	not	RB
cord-350019-4nlbu54e	391	17	be	be	VB
cord-350019-4nlbu54e	391	18	captured	capture	VBN
cord-350019-4nlbu54e	391	19	.	.	.
cord-350019-4nlbu54e	392	1	To	to	TO
cord-350019-4nlbu54e	392	2	overcome	overcome	VB
cord-350019-4nlbu54e	392	3	the	the	DT
cord-350019-4nlbu54e	392	4	limitations	limitation	NNS
cord-350019-4nlbu54e	392	5	of	of	IN
cord-350019-4nlbu54e	392	6	incomplete	incomplete	JJ
cord-350019-4nlbu54e	392	7	transcriptomes	transcriptome	NNS
cord-350019-4nlbu54e	392	8	,	,	,
cord-350019-4nlbu54e	392	9	researchers	researcher	NNS
cord-350019-4nlbu54e	392	10	can	can	MD
cord-350019-4nlbu54e	392	11	perform	perform	VB
cord-350019-4nlbu54e	392	12	de	de	NNP
cord-350019-4nlbu54e	392	13	novo	novo	NNP
cord-350019-4nlbu54e	392	14	transcriptome	transcriptome	NNP
cord-350019-4nlbu54e	392	15	assembly	assembly	NNP
cord-350019-4nlbu54e	392	16	using	use	VBG
cord-350019-4nlbu54e	392	17	short	short	JJ
cord-350019-4nlbu54e	392	18	RNA	RNA	NNP
cord-350019-4nlbu54e	392	19	-	-	HYPH
cord-350019-4nlbu54e	392	20	Seq	Seq	NNP
cord-350019-4nlbu54e	392	21	reads	read	VBZ
cord-350019-4nlbu54e	392	22	[	[	-LRB-
cord-350019-4nlbu54e	392	23	250	250	CD
cord-350019-4nlbu54e	392	24	]	]	-RRB-
cord-350019-4nlbu54e	392	25	[	[	-LRB-
cord-350019-4nlbu54e	392	26	251	251	CD
cord-350019-4nlbu54e	392	27	]	]	-RRB-
cord-350019-4nlbu54e	392	28	[	[	-LRB-
cord-350019-4nlbu54e	392	29	252	252	CD
cord-350019-4nlbu54e	392	30	]	]	-RRB-
cord-350019-4nlbu54e	392	31	.	.	.
cord-350019-4nlbu54e	393	1	The	the	DT
cord-350019-4nlbu54e	393	2	future	future	NN
cord-350019-4nlbu54e	393	3	of	of	IN
cord-350019-4nlbu54e	393	4	RNA	RNA	NNP
cord-350019-4nlbu54e	393	5	sequencing	sequencing	NN
cord-350019-4nlbu54e	393	6	is	be	VBZ
cord-350019-4nlbu54e	393	7	headed	head	VBN
cord-350019-4nlbu54e	393	8	towards	towards	IN
cord-350019-4nlbu54e	393	9	long	long	JJ
cord-350019-4nlbu54e	393	10	read	read	VBN
cord-350019-4nlbu54e	393	11	sequencing	sequencing	NN
cord-350019-4nlbu54e	393	12	,	,	,
cord-350019-4nlbu54e	393	13	which	which	WDT
cord-350019-4nlbu54e	393	14	is	be	VBZ
cord-350019-4nlbu54e	393	15	being	be	VBG
cord-350019-4nlbu54e	393	16	met	meet	VBN
cord-350019-4nlbu54e	393	17	by	by	IN
cord-350019-4nlbu54e	393	18	Pacific	Pacific	NNP
cord-350019-4nlbu54e	393	19	Biosciences	Biosciences	NNP
cord-350019-4nlbu54e	393	20	Single	Single	NNP
cord-350019-4nlbu54e	393	21	Molecule	Molecule	NNP
cord-350019-4nlbu54e	393	22	Real	Real	NNP
cord-350019-4nlbu54e	393	23	Time	time	NN
cord-350019-4nlbu54e	393	24	sequencing	sequencing	NN
cord-350019-4nlbu54e	393	25	technology	technology	NN
cord-350019-4nlbu54e	393	26	(	(	-LRB-
cord-350019-4nlbu54e	393	27	PacBio	pacbio	NN
cord-350019-4nlbu54e	393	28	)	)	-RRB-
cord-350019-4nlbu54e	393	29	and	and	CC
cord-350019-4nlbu54e	393	30	Oxford	Oxford	NNP
cord-350019-4nlbu54e	393	31	Nanopore	Nanopore	NNP
cord-350019-4nlbu54e	393	32	Technology	Technology	NNP
cord-350019-4nlbu54e	393	33	(	(	-LRB-
cord-350019-4nlbu54e	393	34	ONT	ONT	NNP
cord-350019-4nlbu54e	393	35	)	)	-RRB-
cord-350019-4nlbu54e	393	36	[	[	-LRB-
cord-350019-4nlbu54e	393	37	253	253	CD
cord-350019-4nlbu54e	393	38	,	,	,
cord-350019-4nlbu54e	393	39	254	254	CD
cord-350019-4nlbu54e	393	40	]	]	-RRB-
cord-350019-4nlbu54e	393	41	.	.	.
cord-350019-4nlbu54e	394	1	While	while	IN
cord-350019-4nlbu54e	394	2	both	both	DT
cord-350019-4nlbu54e	394	3	powerful	powerful	JJ
cord-350019-4nlbu54e	394	4	technologies	technology	NNS
cord-350019-4nlbu54e	394	5	perform	perform	VBP
cord-350019-4nlbu54e	394	6	long	long	RB
cord-350019-4nlbu54e	394	7	read	read	NN
cord-350019-4nlbu54e	394	8	sequencing	sequencing	NN
cord-350019-4nlbu54e	394	9	,	,	,
cord-350019-4nlbu54e	394	10	their	-PRON-	PRP$
cord-350019-4nlbu54e	394	11	platforms	platform	NNS
cord-350019-4nlbu54e	394	12	are	be	VBP
cord-350019-4nlbu54e	394	13	very	very	RB
cord-350019-4nlbu54e	394	14	different	different	JJ
cord-350019-4nlbu54e	394	15	.	.	.
cord-350019-4nlbu54e	395	1	PacBio	pacbio	NN
cord-350019-4nlbu54e	395	2	technology	technology	NN
cord-350019-4nlbu54e	395	3	is	be	VBZ
cord-350019-4nlbu54e	395	4	dependent	dependent	JJ
cord-350019-4nlbu54e	395	5	on	on	IN
cord-350019-4nlbu54e	395	6	sequencing	sequencing	NN
cord-350019-4nlbu54e	395	7	-	-	HYPH
cord-350019-4nlbu54e	395	8	by	by	IN
cord-350019-4nlbu54e	395	9	-	-	HYPH
cord-350019-4nlbu54e	395	10	synthesis	synthesis	NN
cord-350019-4nlbu54e	395	11	.	.	.
cord-350019-4nlbu54e	396	1	A	a	DT
cord-350019-4nlbu54e	396	2	DNA	dna	NN
cord-350019-4nlbu54e	396	3	polymerase	polymerase	NN
cord-350019-4nlbu54e	396	4	incorporates	incorporate	VBZ
cord-350019-4nlbu54e	396	5	nucleotides	nucleotide	NNS
cord-350019-4nlbu54e	396	6	that	that	IN
cord-350019-4nlbu54e	396	7	each	each	DT
cord-350019-4nlbu54e	396	8	have	have	VBP
cord-350019-4nlbu54e	396	9	a	a	DT
cord-350019-4nlbu54e	396	10	corresponding	corresponding	JJ
cord-350019-4nlbu54e	396	11	conjugated	conjugated	JJ
cord-350019-4nlbu54e	396	12	fluorescent	fluorescent	JJ
cord-350019-4nlbu54e	396	13	dye	dye	NN
cord-350019-4nlbu54e	396	14	.	.	.
cord-350019-4nlbu54e	397	1	The	the	DT
cord-350019-4nlbu54e	397	2	DNA	dna	NN
cord-350019-4nlbu54e	397	3	polymerase	polymerase	NN
cord-350019-4nlbu54e	397	4	works	work	VBZ
cord-350019-4nlbu54e	397	5	at	at	IN
cord-350019-4nlbu54e	397	6	a	a	DT
cord-350019-4nlbu54e	397	7	rate	rate	NN
cord-350019-4nlbu54e	397	8	of	of	IN
cord-350019-4nlbu54e	397	9	1000	1000	CD
cord-350019-4nlbu54e	397	10	bp	bp	NNP
cord-350019-4nlbu54e	397	11	/	/	SYM
cord-350019-4nlbu54e	397	12	s	s	NNP
cord-350019-4nlbu54e	397	13	,	,	,
cord-350019-4nlbu54e	397	14	which	which	WDT
cord-350019-4nlbu54e	397	15	is	be	VBZ
cord-350019-4nlbu54e	397	16	beyond	beyond	IN
cord-350019-4nlbu54e	397	17	the	the	DT
cord-350019-4nlbu54e	397	18	capabilities	capability	NNS
cord-350019-4nlbu54e	397	19	of	of	IN
cord-350019-4nlbu54e	397	20	current	current	JJ
cord-350019-4nlbu54e	397	21	technologies	technology	NNS
cord-350019-4nlbu54e	397	22	.	.	.
cord-350019-4nlbu54e	398	1	However	however	RB
cord-350019-4nlbu54e	398	2	,	,	,
cord-350019-4nlbu54e	398	3	by	by	IN
cord-350019-4nlbu54e	398	4	circularizing	circularize	VBG
cord-350019-4nlbu54e	398	5	the	the	DT
cord-350019-4nlbu54e	398	6	DNA	DNA	NNP
cord-350019-4nlbu54e	398	7	PacBio	PacBio	NNP
cord-350019-4nlbu54e	398	8	has	have	VBZ
cord-350019-4nlbu54e	398	9	overcome	overcome	VBN
cord-350019-4nlbu54e	398	10	this	this	DT
cord-350019-4nlbu54e	398	11	limitation	limitation	NN
cord-350019-4nlbu54e	398	12	through	through	IN
cord-350019-4nlbu54e	398	13	continuous	continuous	JJ
cord-350019-4nlbu54e	398	14	long	long	JJ
cord-350019-4nlbu54e	398	15	read	read	NN
cord-350019-4nlbu54e	398	16	sequencing	sequencing	NN
cord-350019-4nlbu54e	398	17	,	,	,
cord-350019-4nlbu54e	398	18	resulting	result	VBG
cord-350019-4nlbu54e	398	19	in	in	IN
cord-350019-4nlbu54e	398	20	ability	ability	NN
cord-350019-4nlbu54e	398	21	to	to	TO
cord-350019-4nlbu54e	398	22	generate	generate	VB
cord-350019-4nlbu54e	398	23	500k-4million	500k-4million	NN
cord-350019-4nlbu54e	398	24	reads	read	VBZ
cord-350019-4nlbu54e	398	25	at	at	IN
cord-350019-4nlbu54e	398	26	an	an	DT
cord-350019-4nlbu54e	398	27	error	error	NN
cord-350019-4nlbu54e	398	28	rate	rate	NN
cord-350019-4nlbu54e	398	29	of	of	IN
cord-350019-4nlbu54e	398	30	below	below	IN
cord-350019-4nlbu54e	398	31	1	1	CD
cord-350019-4nlbu54e	398	32	%	%	NN
cord-350019-4nlbu54e	398	33	[	[	-LRB-
cord-350019-4nlbu54e	398	34	255	255	CD
cord-350019-4nlbu54e	398	35	,	,	,
cord-350019-4nlbu54e	398	36	256	256	CD
cord-350019-4nlbu54e	398	37	]	]	-RRB-
cord-350019-4nlbu54e	398	38	.	.	.
cord-350019-4nlbu54e	399	1	On	on	IN
cord-350019-4nlbu54e	399	2	the	the	DT
cord-350019-4nlbu54e	399	3	other	other	JJ
cord-350019-4nlbu54e	399	4	hand	hand	NN
cord-350019-4nlbu54e	399	5	,	,	,
cord-350019-4nlbu54e	399	6	ONT	ONT	NNP
cord-350019-4nlbu54e	399	7	's	's	POS
cord-350019-4nlbu54e	399	8	approach	approach	NN
cord-350019-4nlbu54e	399	9	relies	rely	VBZ
cord-350019-4nlbu54e	399	10	on	on	IN
cord-350019-4nlbu54e	399	11	a	a	DT
cord-350019-4nlbu54e	399	12	pore	pore	NN
cord-350019-4nlbu54e	399	13	embedded	embed	VBN
cord-350019-4nlbu54e	399	14	in	in	IN
cord-350019-4nlbu54e	399	15	a	a	DT
cord-350019-4nlbu54e	399	16	membrane	membrane	NN
cord-350019-4nlbu54e	399	17	.	.	.
cord-350019-4nlbu54e	400	1	As	as	IN
cord-350019-4nlbu54e	400	2	a	a	DT
cord-350019-4nlbu54e	400	3	long	long	JJ
cord-350019-4nlbu54e	400	4	cDNA	cdna	NN
cord-350019-4nlbu54e	400	5	or	or	CC
cord-350019-4nlbu54e	400	6	RNA	RNA	NNP
cord-350019-4nlbu54e	400	7	strand	strand	NN
cord-350019-4nlbu54e	400	8	translocates	translocate	NNS
cord-350019-4nlbu54e	400	9	through	through	IN
cord-350019-4nlbu54e	400	10	the	the	DT
cord-350019-4nlbu54e	400	11	nanopore	nanopore	NNP
cord-350019-4nlbu54e	400	12	at	at	IN
cord-350019-4nlbu54e	400	13	single	single	JJ
cord-350019-4nlbu54e	400	14	nucleotide	nucleotide	JJ
cord-350019-4nlbu54e	400	15	precision	precision	NN
cord-350019-4nlbu54e	400	16	from	from	IN
cord-350019-4nlbu54e	400	17	enzymatic	enzymatic	JJ
cord-350019-4nlbu54e	400	18	regulation	regulation	NN
cord-350019-4nlbu54e	400	19	,	,	,
cord-350019-4nlbu54e	400	20	the	the	DT
cord-350019-4nlbu54e	400	21	ionic	ionic	JJ
cord-350019-4nlbu54e	400	22	current	current	NN
cord-350019-4nlbu54e	400	23	across	across	IN
cord-350019-4nlbu54e	400	24	the	the	DT
cord-350019-4nlbu54e	400	25	membrane	membrane	NN
cord-350019-4nlbu54e	400	26	is	be	VBZ
cord-350019-4nlbu54e	400	27	recorded	record	VBN
cord-350019-4nlbu54e	400	28	.	.	.
cord-350019-4nlbu54e	401	1	This	this	DT
cord-350019-4nlbu54e	401	2	technology	technology	NN
cord-350019-4nlbu54e	401	3	can	can	MD
cord-350019-4nlbu54e	401	4	sequence	sequence	VB
cord-350019-4nlbu54e	401	5	full	full	JJ
cord-350019-4nlbu54e	401	6	-	-	HYPH
cord-350019-4nlbu54e	401	7	length	length	NN
cord-350019-4nlbu54e	401	8	transcripts	transcript	NNS
cord-350019-4nlbu54e	401	9	and	and	CC
cord-350019-4nlbu54e	401	10	can	can	MD
cord-350019-4nlbu54e	401	11	yield	yield	VB
cord-350019-4nlbu54e	401	12	up	up	IN
cord-350019-4nlbu54e	401	13	to	to	TO
cord-350019-4nlbu54e	401	14	10	10	CD
cord-350019-4nlbu54e	401	15	million	million	CD
cord-350019-4nlbu54e	401	16	reads	read	NNS
cord-350019-4nlbu54e	401	17	on	on	IN
cord-350019-4nlbu54e	401	18	the	the	DT
cord-350019-4nlbu54e	401	19	MinION	minion	NN
cord-350019-4nlbu54e	401	20	or	or	CC
cord-350019-4nlbu54e	401	21	up	up	IN
cord-350019-4nlbu54e	401	22	to	to	TO
cord-350019-4nlbu54e	401	23	60	60	CD
cord-350019-4nlbu54e	401	24	million	million	CD
cord-350019-4nlbu54e	401	25	reads	read	NNS
cord-350019-4nlbu54e	401	26	on	on	IN
cord-350019-4nlbu54e	401	27	the	the	DT
cord-350019-4nlbu54e	401	28	PromethION	PromethION	NNP
cord-350019-4nlbu54e	401	29	for	for	IN
cord-350019-4nlbu54e	401	30	cDNA	cDNA	NNP
cord-350019-4nlbu54e	401	31	[	[	-LRB-
cord-350019-4nlbu54e	401	32	257	257	CD
cord-350019-4nlbu54e	401	33	,	,	,
cord-350019-4nlbu54e	401	34	258	258	CD
cord-350019-4nlbu54e	401	35	]	]	-RRB-
cord-350019-4nlbu54e	401	36	.	.	.
cord-350019-4nlbu54e	402	1	An	an	DT
cord-350019-4nlbu54e	402	2	initial	initial	JJ
cord-350019-4nlbu54e	402	3	limitation	limitation	NN
cord-350019-4nlbu54e	402	4	of	of	IN
cord-350019-4nlbu54e	402	5	ONT	ONT	NNP
cord-350019-4nlbu54e	402	6	was	be	VBD
cord-350019-4nlbu54e	402	7	the	the	DT
cord-350019-4nlbu54e	402	8	5	5	CD
cord-350019-4nlbu54e	402	9	-	-	SYM
cord-350019-4nlbu54e	402	10	10	10	CD
cord-350019-4nlbu54e	402	11	%	%	NN
cord-350019-4nlbu54e	402	12	per	per	IN
cord-350019-4nlbu54e	402	13	read	read	NN
cord-350019-4nlbu54e	402	14	error	error	NN
cord-350019-4nlbu54e	402	15	rate	rate	NN
cord-350019-4nlbu54e	402	16	,	,	,
cord-350019-4nlbu54e	402	17	which	which	WDT
cord-350019-4nlbu54e	402	18	has	have	VBZ
cord-350019-4nlbu54e	402	19	been	be	VBN
cord-350019-4nlbu54e	402	20	overcome	overcome	VBN
cord-350019-4nlbu54e	402	21	with	with	IN
cord-350019-4nlbu54e	402	22	a	a	DT
cord-350019-4nlbu54e	402	23	new	new	JJ
cord-350019-4nlbu54e	402	24	technology	technology	NN
cord-350019-4nlbu54e	402	25	called	call	VBN
cord-350019-4nlbu54e	402	26	Rolling	Rolling	NNP
cord-350019-4nlbu54e	402	27	Circle	Circle	NNP
cord-350019-4nlbu54e	402	28	to	to	IN
cord-350019-4nlbu54e	402	29	Concatemeric	Concatemeric	NNP
cord-350019-4nlbu54e	402	30	Consensus	Consensus	NNP
cord-350019-4nlbu54e	402	31	(	(	-LRB-
cord-350019-4nlbu54e	402	32	R2C2	R2C2	NNP
cord-350019-4nlbu54e	402	33	)	)	-RRB-
cord-350019-4nlbu54e	402	34	bringing	bring	VBG
cord-350019-4nlbu54e	402	35	the	the	DT
cord-350019-4nlbu54e	402	36	error	error	NN
cord-350019-4nlbu54e	402	37	rate	rate	NN
cord-350019-4nlbu54e	402	38	down	down	RB
cord-350019-4nlbu54e	402	39	to	to	IN
cord-350019-4nlbu54e	402	40	2.5	2.5	CD
cord-350019-4nlbu54e	402	41	%	%	NN
cord-350019-4nlbu54e	402	42	by	by	IN
cord-350019-4nlbu54e	402	43	increasing	increase	VBG
cord-350019-4nlbu54e	402	44	the	the	DT
cord-350019-4nlbu54e	402	45	read	read	VBN
cord-350019-4nlbu54e	402	46	coverage	coverage	NN
cord-350019-4nlbu54e	402	47	.	.	.
cord-350019-4nlbu54e	403	1	Overall	overall	RB
cord-350019-4nlbu54e	403	2	,	,	,
cord-350019-4nlbu54e	403	3	both	both	DT
cord-350019-4nlbu54e	403	4	of	of	IN
cord-350019-4nlbu54e	403	5	these	these	DT
cord-350019-4nlbu54e	403	6	technologies	technology	NNS
cord-350019-4nlbu54e	403	7	have	have	VBP
cord-350019-4nlbu54e	403	8	overcome	overcome	VBN
cord-350019-4nlbu54e	403	9	the	the	DT
cord-350019-4nlbu54e	403	10	transcriptome	transcriptome	NN
cord-350019-4nlbu54e	403	11	assembly	assembly	NN
cord-350019-4nlbu54e	403	12	and	and	CC
cord-350019-4nlbu54e	403	13	isoform	isoform	NN
cord-350019-4nlbu54e	403	14	identification	identification	NN
cord-350019-4nlbu54e	403	15	limitations	limitation	NNS
cord-350019-4nlbu54e	403	16	of	of	IN
cord-350019-4nlbu54e	403	17	short	short	RB
cord-350019-4nlbu54e	403	18	-	-	HYPH
cord-350019-4nlbu54e	403	19	read	read	VBN
cord-350019-4nlbu54e	403	20	Illumina	Illumina	NNP
cord-350019-4nlbu54e	403	21	sequencing	sequencing	NN
cord-350019-4nlbu54e	403	22	[	[	-LRB-
cord-350019-4nlbu54e	403	23	259	259	CD
cord-350019-4nlbu54e	403	24	]	]	-RRB-
cord-350019-4nlbu54e	403	25	.	.	.
cord-350019-4nlbu54e	404	1	As	as	IN
cord-350019-4nlbu54e	404	2	stated	state	VBN
cord-350019-4nlbu54e	404	3	above	above	RB
cord-350019-4nlbu54e	404	4	,	,	,
cord-350019-4nlbu54e	404	5	ONT	ONT	NNP
cord-350019-4nlbu54e	404	6	and	and	CC
cord-350019-4nlbu54e	404	7	PacBio	PacBio	NNP
cord-350019-4nlbu54e	404	8	can	can	MD
cord-350019-4nlbu54e	404	9	perform	perform	VB
cord-350019-4nlbu54e	404	10	long	long	RB
cord-350019-4nlbu54e	404	11	read	read	VB
cord-350019-4nlbu54e	404	12	cDNA	cdna	NN
cord-350019-4nlbu54e	404	13	sequencing	sequencing	NN
cord-350019-4nlbu54e	404	14	[	[	-LRB-
cord-350019-4nlbu54e	404	15	260	260	CD
cord-350019-4nlbu54e	404	16	]	]	-RRB-
cord-350019-4nlbu54e	404	17	and	and	CC
cord-350019-4nlbu54e	404	18	even	even	RB
cord-350019-4nlbu54e	404	19	more	more	RBR
cord-350019-4nlbu54e	404	20	exciting	exciting	JJ
cord-350019-4nlbu54e	404	21	,	,	,
cord-350019-4nlbu54e	404	22	both	both	DT
cord-350019-4nlbu54e	404	23	technologies	technology	NNS
cord-350019-4nlbu54e	404	24	can	can	MD
cord-350019-4nlbu54e	404	25	perform	perform	VB
cord-350019-4nlbu54e	404	26	direct	direct	JJ
cord-350019-4nlbu54e	404	27	long	long	JJ
cord-350019-4nlbu54e	404	28	read	read	NN
cord-350019-4nlbu54e	404	29	RNA	rna	NN
cord-350019-4nlbu54e	404	30	sequencing	sequencing	NN
cord-350019-4nlbu54e	404	31	[	[	-LRB-
cord-350019-4nlbu54e	404	32	261	261	CD
cord-350019-4nlbu54e	404	33	,	,	,
cord-350019-4nlbu54e	404	34	262	262	CD
cord-350019-4nlbu54e	404	35	]	]	-RRB-
cord-350019-4nlbu54e	404	36	.	.	.
cord-350019-4nlbu54e	405	1	The	the	DT
cord-350019-4nlbu54e	405	2	beauty	beauty	NN
cord-350019-4nlbu54e	405	3	and	and	CC
cord-350019-4nlbu54e	405	4	simplicity	simplicity	NN
cord-350019-4nlbu54e	405	5	that	that	WDT
cord-350019-4nlbu54e	405	6	ONT	ONT	NNP
cord-350019-4nlbu54e	405	7	and	and	CC
cord-350019-4nlbu54e	405	8	PacBio	PacBio	NNP
cord-350019-4nlbu54e	405	9	offers	offer	VBZ
cord-350019-4nlbu54e	405	10	is	be	VBZ
cord-350019-4nlbu54e	405	11	the	the	DT
cord-350019-4nlbu54e	405	12	ability	ability	NN
cord-350019-4nlbu54e	405	13	to	to	TO
cord-350019-4nlbu54e	405	14	sequence	sequence	VB
cord-350019-4nlbu54e	405	15	the	the	DT
cord-350019-4nlbu54e	405	16	full	full	JJ
cord-350019-4nlbu54e	405	17	expressed	express	VBN
cord-350019-4nlbu54e	405	18	isoform	isoform	NN
cord-350019-4nlbu54e	405	19	(	(	-LRB-
cord-350019-4nlbu54e	405	20	cDNA	cdna	NN
cord-350019-4nlbu54e	405	21	and	and	CC
cord-350019-4nlbu54e	405	22	direct	direct	NNP
cord-350019-4nlbu54e	405	23	RNA	RNA	NNP
cord-350019-4nlbu54e	405	24	)	)	-RRB-
cord-350019-4nlbu54e	405	25	,	,	,
cord-350019-4nlbu54e	405	26	without	without	IN
cord-350019-4nlbu54e	405	27	worries	worry	NNS
cord-350019-4nlbu54e	405	28	of	of	IN
cord-350019-4nlbu54e	405	29	misidentifying	misidentify	VBG
cord-350019-4nlbu54e	405	30	a	a	DT
cord-350019-4nlbu54e	405	31	complex	complex	JJ
cord-350019-4nlbu54e	405	32	splicing	splicing	NN
cord-350019-4nlbu54e	405	33	pattern	pattern	NN
cord-350019-4nlbu54e	405	34	,	,	,
cord-350019-4nlbu54e	405	35	RNA	rna	NN
cord-350019-4nlbu54e	405	36	cleavage	cleavage	NN
cord-350019-4nlbu54e	405	37	events	event	NNS
cord-350019-4nlbu54e	405	38	and	and	CC
cord-350019-4nlbu54e	405	39	also	also	RB
cord-350019-4nlbu54e	405	40	not	not	RB
cord-350019-4nlbu54e	405	41	relying	rely	VBG
cord-350019-4nlbu54e	405	42	on	on	IN
cord-350019-4nlbu54e	405	43	transcript	transcript	NN
cord-350019-4nlbu54e	405	44	annotation	annotation	NN
cord-350019-4nlbu54e	405	45	files	file	NNS
cord-350019-4nlbu54e	405	46	will	will	MD
cord-350019-4nlbu54e	405	47	lead	lead	VB
cord-350019-4nlbu54e	405	48	to	to	IN
cord-350019-4nlbu54e	405	49	the	the	DT
cord-350019-4nlbu54e	405	50	identification	identification	NN
cord-350019-4nlbu54e	405	51	of	of	IN
cord-350019-4nlbu54e	405	52	novel	novel	JJ
cord-350019-4nlbu54e	405	53	isoforms	isoform	NNS
cord-350019-4nlbu54e	405	54	which	which	WDT
cord-350019-4nlbu54e	405	55	are	be	VBP
cord-350019-4nlbu54e	405	56	problems	problem	NNS
cord-350019-4nlbu54e	405	57	faced	face	VBN
cord-350019-4nlbu54e	405	58	using	use	VBG
cord-350019-4nlbu54e	405	59	short	short	RB
cord-350019-4nlbu54e	405	60	-	-	HYPH
cord-350019-4nlbu54e	405	61	read	read	VBN
cord-350019-4nlbu54e	405	62	Illumina	Illumina	NNP
cord-350019-4nlbu54e	405	63	sequencing	sequencing	NN
cord-350019-4nlbu54e	405	64	.	.	.
cord-350019-4nlbu54e	406	1	For	for	IN
cord-350019-4nlbu54e	406	2	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	406	3	there	there	EX
cord-350019-4nlbu54e	406	4	have	have	VBP
cord-350019-4nlbu54e	406	5	been	be	VBN
cord-350019-4nlbu54e	406	6	a	a	DT
cord-350019-4nlbu54e	406	7	couple	couple	NN
cord-350019-4nlbu54e	406	8	of	of	IN
cord-350019-4nlbu54e	406	9	studies	study	NNS
cord-350019-4nlbu54e	406	10	that	that	WDT
cord-350019-4nlbu54e	406	11	focus	focus	VBP
cord-350019-4nlbu54e	406	12	on	on	IN
cord-350019-4nlbu54e	406	13	isoform	isoform	NN
cord-350019-4nlbu54e	406	14	specificity	specificity	NN
cord-350019-4nlbu54e	406	15	and	and	CC
cord-350019-4nlbu54e	406	16	function	function	NN
cord-350019-4nlbu54e	406	17	for	for	IN
cord-350019-4nlbu54e	406	18	a	a	DT
cord-350019-4nlbu54e	406	19	given	give	VBN
cord-350019-4nlbu54e	406	20	lncRNA	lncrna	NN
cord-350019-4nlbu54e	406	21	.	.	.
cord-350019-4nlbu54e	407	1	Neat1	Neat1	NNP
cord-350019-4nlbu54e	408	1	[	[	-LRB-
cord-350019-4nlbu54e	408	2	263	263	CD
cord-350019-4nlbu54e	408	3	]	]	-RRB-
cord-350019-4nlbu54e	408	4	and	and	CC
cord-350019-4nlbu54e	408	5	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	408	6	-	-	HYPH
cord-350019-4nlbu54e	408	7	PXN	PXN	NNP
cord-350019-4nlbu54e	408	8	-	-	HYPH
cord-350019-4nlbu54e	408	9	AS1	AS1	NNP
cord-350019-4nlbu54e	408	10	[	[	-LRB-
cord-350019-4nlbu54e	408	11	264	264	CD
cord-350019-4nlbu54e	408	12	]	]	-RRB-
cord-350019-4nlbu54e	408	13	are	be	VBP
cord-350019-4nlbu54e	408	14	two	two	CD
cord-350019-4nlbu54e	408	15	studies	study	NNS
cord-350019-4nlbu54e	408	16	that	that	WDT
cord-350019-4nlbu54e	408	17	show	show	VBP
cord-350019-4nlbu54e	408	18	how	how	WRB
cord-350019-4nlbu54e	408	19	one	one	CD
cord-350019-4nlbu54e	408	20	gene	gene	NN
cord-350019-4nlbu54e	408	21	can	can	MD
cord-350019-4nlbu54e	408	22	have	have	VB
cord-350019-4nlbu54e	408	23	different	different	JJ
cord-350019-4nlbu54e	408	24	functions	function	NNS
cord-350019-4nlbu54e	408	25	depending	depend	VBG
cord-350019-4nlbu54e	408	26	on	on	IN
cord-350019-4nlbu54e	408	27	the	the	DT
cord-350019-4nlbu54e	408	28	RNA	RNA	NNP
cord-350019-4nlbu54e	408	29	isoform	isoform	NN
cord-350019-4nlbu54e	408	30	expressed	express	VBD
cord-350019-4nlbu54e	408	31	.	.	.
cord-350019-4nlbu54e	409	1	While	while	IN
cord-350019-4nlbu54e	409	2	these	these	DT
cord-350019-4nlbu54e	409	3	studies	study	NNS
cord-350019-4nlbu54e	409	4	are	be	VBP
cord-350019-4nlbu54e	409	5	not	not	RB
cord-350019-4nlbu54e	409	6	immunology	immunology	NN
cord-350019-4nlbu54e	409	7	specific	specific	JJ
cord-350019-4nlbu54e	409	8	,	,	,
cord-350019-4nlbu54e	409	9	this	this	DT
cord-350019-4nlbu54e	409	10	field	field	NN
cord-350019-4nlbu54e	409	11	is	be	VBZ
cord-350019-4nlbu54e	409	12	still	still	RB
cord-350019-4nlbu54e	409	13	at	at	IN
cord-350019-4nlbu54e	409	14	the	the	DT
cord-350019-4nlbu54e	409	15	early	early	JJ
cord-350019-4nlbu54e	409	16	stages	stage	NNS
cord-350019-4nlbu54e	409	17	and	and	CC
cord-350019-4nlbu54e	409	18	we	-PRON-	PRP
cord-350019-4nlbu54e	409	19	anticipate	anticipate	VBP
cord-350019-4nlbu54e	409	20	it	-PRON-	PRP
cord-350019-4nlbu54e	409	21	becoming	become	VBG
cord-350019-4nlbu54e	409	22	more	more	RBR
cord-350019-4nlbu54e	409	23	prevalent	prevalent	JJ
cord-350019-4nlbu54e	409	24	in	in	IN
cord-350019-4nlbu54e	409	25	future	future	JJ
cord-350019-4nlbu54e	409	26	studies	study	NNS
cord-350019-4nlbu54e	409	27	.	.	.
cord-350019-4nlbu54e	410	1	RNA	RNA	NNP
cord-350019-4nlbu54e	410	2	modifications	modification	NNS
cord-350019-4nlbu54e	410	3	are	be	VBP
cord-350019-4nlbu54e	410	4	widespread	widespread	JJ
cord-350019-4nlbu54e	410	5	and	and	CC
cord-350019-4nlbu54e	410	6	diverse	diverse	JJ
cord-350019-4nlbu54e	410	7	in	in	IN
cord-350019-4nlbu54e	410	8	chemical	chemical	JJ
cord-350019-4nlbu54e	410	9	nature	nature	NN
cord-350019-4nlbu54e	410	10	,	,	,
cord-350019-4nlbu54e	410	11	as	as	RB
cord-350019-4nlbu54e	410	12	well	well	RB
cord-350019-4nlbu54e	410	13	as	as	IN
cord-350019-4nlbu54e	410	14	highly	highly	RB
cord-350019-4nlbu54e	410	15	conserved	conserve	VBN
cord-350019-4nlbu54e	410	16	in	in	IN
cord-350019-4nlbu54e	410	17	their	-PRON-	PRP$
cord-350019-4nlbu54e	410	18	occurrence	occurrence	NN
cord-350019-4nlbu54e	410	19	and	and	CC
cord-350019-4nlbu54e	410	20	function	function	VB
cord-350019-4nlbu54e	410	21	throughout	throughout	IN
cord-350019-4nlbu54e	410	22	species	specie	NNS
cord-350019-4nlbu54e	410	23	.	.	.
cord-350019-4nlbu54e	411	1	RNA	RNA	NNP
cord-350019-4nlbu54e	411	2	modifications	modification	NNS
cord-350019-4nlbu54e	411	3	function	function	VBP
cord-350019-4nlbu54e	411	4	to	to	TO
cord-350019-4nlbu54e	411	5	affect	affect	VB
cord-350019-4nlbu54e	411	6	RNA	RNA	NNP
cord-350019-4nlbu54e	411	7	stability	stability	NN
cord-350019-4nlbu54e	411	8	,	,	,
cord-350019-4nlbu54e	411	9	localization	localization	NN
cord-350019-4nlbu54e	411	10	,	,	,
cord-350019-4nlbu54e	411	11	alternative	alternative	JJ
cord-350019-4nlbu54e	411	12	site	site	NN
cord-350019-4nlbu54e	411	13	of	of	IN
cord-350019-4nlbu54e	411	14	poly	poly	NN
cord-350019-4nlbu54e	411	15	-	-	HYPH
cord-350019-4nlbu54e	411	16	adenylation	adenylation	NN
cord-350019-4nlbu54e	411	17	,	,	,
cord-350019-4nlbu54e	411	18	and	and	CC
cord-350019-4nlbu54e	411	19	more	more	JJR
cord-350019-4nlbu54e	411	20	[	[	-LRB-
cord-350019-4nlbu54e	411	21	265	265	CD
cord-350019-4nlbu54e	411	22	]	]	-RRB-
cord-350019-4nlbu54e	411	23	.	.	.
cord-350019-4nlbu54e	412	1	Since	since	IN
cord-350019-4nlbu54e	412	2	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	412	3	can	can	MD
cord-350019-4nlbu54e	412	4	function	function	VB
cord-350019-4nlbu54e	412	5	as	as	IN
cord-350019-4nlbu54e	412	6	decoys	decoy	NNS
cord-350019-4nlbu54e	412	7	and	and	CC
cord-350019-4nlbu54e	412	8	scaffolds	scaffold	NNS
cord-350019-4nlbu54e	412	9	,	,	,
cord-350019-4nlbu54e	412	10	which	which	WDT
cord-350019-4nlbu54e	412	11	are	be	VBP
cord-350019-4nlbu54e	412	12	highly	highly	RB
cord-350019-4nlbu54e	412	13	dependent	dependent	JJ
cord-350019-4nlbu54e	412	14	on	on	IN
cord-350019-4nlbu54e	412	15	RNA	RNA	NNP
cord-350019-4nlbu54e	412	16	structure	structure	NN
cord-350019-4nlbu54e	412	17	,	,	,
cord-350019-4nlbu54e	412	18	a	a	DT
cord-350019-4nlbu54e	412	19	single	single	JJ
cord-350019-4nlbu54e	412	20	modification	modification	NN
cord-350019-4nlbu54e	412	21	can	can	MD
cord-350019-4nlbu54e	412	22	enhance	enhance	VB
cord-350019-4nlbu54e	412	23	or	or	CC
cord-350019-4nlbu54e	412	24	eradicate	eradicate	VB
cord-350019-4nlbu54e	412	25	this	this	DT
cord-350019-4nlbu54e	412	26	RNA	rna	NN
cord-350019-4nlbu54e	412	27	-	-	HYPH
cord-350019-4nlbu54e	412	28	protein	protein	NN
cord-350019-4nlbu54e	412	29	interaction	interaction	NN
cord-350019-4nlbu54e	412	30	.	.	.
cord-350019-4nlbu54e	413	1	As	as	IN
cord-350019-4nlbu54e	413	2	you	-PRON-	PRP
cord-350019-4nlbu54e	413	3	study	study	VBP
cord-350019-4nlbu54e	413	4	a	a	DT
cord-350019-4nlbu54e	413	5	lncRNA	lncrna	NN
cord-350019-4nlbu54e	413	6	,	,	,
cord-350019-4nlbu54e	413	7	the	the	DT
cord-350019-4nlbu54e	413	8	mechanism	mechanism	NN
cord-350019-4nlbu54e	413	9	of	of	IN
cord-350019-4nlbu54e	413	10	this	this	DT
cord-350019-4nlbu54e	413	11	molecule	molecule	NN
cord-350019-4nlbu54e	413	12	could	could	MD
cord-350019-4nlbu54e	413	13	be	be	VB
cord-350019-4nlbu54e	413	14	dependent	dependent	JJ
cord-350019-4nlbu54e	413	15	on	on	IN
cord-350019-4nlbu54e	413	16	a	a	DT
cord-350019-4nlbu54e	413	17	modified	modify	VBN
cord-350019-4nlbu54e	413	18	nucleotide	nucleotide	NN
cord-350019-4nlbu54e	413	19	.	.	.
cord-350019-4nlbu54e	414	1	There	there	EX
cord-350019-4nlbu54e	414	2	are	be	VBP
cord-350019-4nlbu54e	414	3	many	many	JJ
cord-350019-4nlbu54e	414	4	techniques	technique	NNS
cord-350019-4nlbu54e	414	5	used	use	VBN
cord-350019-4nlbu54e	414	6	to	to	TO
cord-350019-4nlbu54e	414	7	determine	determine	VB
cord-350019-4nlbu54e	414	8	a	a	DT
cord-350019-4nlbu54e	414	9	single	single	JJ
cord-350019-4nlbu54e	414	10	RNA	RNA	NNP
cord-350019-4nlbu54e	414	11	modification	modification	NN
cord-350019-4nlbu54e	414	12	in	in	IN
cord-350019-4nlbu54e	414	13	a	a	DT
cord-350019-4nlbu54e	414	14	cell	cell	NN
cord-350019-4nlbu54e	414	15	type	type	NN
cord-350019-4nlbu54e	414	16	and	and	CC
cord-350019-4nlbu54e	414	17	biology	biology	NN
cord-350019-4nlbu54e	414	18	of	of	IN
cord-350019-4nlbu54e	414	19	choice	choice	NN
cord-350019-4nlbu54e	414	20	.	.	.
cord-350019-4nlbu54e	415	1	Site	site	NN
cord-350019-4nlbu54e	415	2	-	-	HYPH
cord-350019-4nlbu54e	415	3	specific	specific	JJ
cord-350019-4nlbu54e	415	4	Cleavage	cleavage	NN
cord-350019-4nlbu54e	415	5	and	and	CC
cord-350019-4nlbu54e	415	6	Radioactive	Radioactive	NNP
cord-350019-4nlbu54e	415	7	-	-	HYPH
cord-350019-4nlbu54e	415	8	labeling	labeling	NN
cord-350019-4nlbu54e	415	9	followed	follow	VBN
cord-350019-4nlbu54e	415	10	by	by	IN
cord-350019-4nlbu54e	415	11	ligation	ligation	NN
cord-350019-4nlbu54e	415	12	-	-	HYPH
cord-350019-4nlbu54e	415	13	assisted	assist	VBN
cord-350019-4nlbu54e	415	14	extraction	extraction	NN
cord-350019-4nlbu54e	415	15	and	and	CC
cord-350019-4nlbu54e	415	16	TLC	TLC	NNP
cord-350019-4nlbu54e	415	17	(	(	-LRB-
cord-350019-4nlbu54e	415	18	SCARLET	SCARLET	NNP
cord-350019-4nlbu54e	415	19	)	)	-RRB-
cord-350019-4nlbu54e	415	20	Technology	technology	NN
cord-350019-4nlbu54e	415	21	give	give	VBP
cord-350019-4nlbu54e	415	22	scientists	scientist	NNS
cord-350019-4nlbu54e	415	23	the	the	DT
cord-350019-4nlbu54e	415	24	ability	ability	NN
cord-350019-4nlbu54e	415	25	to	to	TO
cord-350019-4nlbu54e	415	26	probe	probe	VB
cord-350019-4nlbu54e	415	27	for	for	IN
cord-350019-4nlbu54e	415	28	N6-methyladenosine	N6-methyladenosine	NNP
cord-350019-4nlbu54e	415	29	RNA	RNA	NNP
cord-350019-4nlbu54e	415	30	(	(	-LRB-
cord-350019-4nlbu54e	415	31	m6A	m6a	NN
cord-350019-4nlbu54e	415	32	)	)	-RRB-
cord-350019-4nlbu54e	415	33	modification	modification	NN
cord-350019-4nlbu54e	415	34	status	status	NN
cord-350019-4nlbu54e	415	35	at	at	IN
cord-350019-4nlbu54e	415	36	single	single	JJ
cord-350019-4nlbu54e	415	37	nucleotide	nucleotide	JJ
cord-350019-4nlbu54e	415	38	resolution	resolution	NN
cord-350019-4nlbu54e	415	39	in	in	IN
cord-350019-4nlbu54e	415	40	mRNA	mRNA	NNP
cord-350019-4nlbu54e	415	41	and	and	CC
cord-350019-4nlbu54e	415	42	long	long	JJ
cord-350019-4nlbu54e	415	43	noncoding	noncoding	NNP
cord-350019-4nlbu54e	415	44	RNA	RNA	NNP
cord-350019-4nlbu54e	415	45	[	[	-LRB-
cord-350019-4nlbu54e	415	46	266	266	CD
cord-350019-4nlbu54e	415	47	]	]	-RRB-
cord-350019-4nlbu54e	415	48	.	.	.
cord-350019-4nlbu54e	416	1	The	the	DT
cord-350019-4nlbu54e	416	2	significance	significance	NN
cord-350019-4nlbu54e	416	3	of	of	IN
cord-350019-4nlbu54e	416	4	RNA	RNA	NNP
cord-350019-4nlbu54e	416	5	modifications	modification	NNS
cord-350019-4nlbu54e	416	6	to	to	IN
cord-350019-4nlbu54e	416	7	the	the	DT
cord-350019-4nlbu54e	416	8	control	control	NN
cord-350019-4nlbu54e	416	9	of	of	IN
cord-350019-4nlbu54e	416	10	the	the	DT
cord-350019-4nlbu54e	416	11	immune	immune	JJ
cord-350019-4nlbu54e	416	12	response	response	NN
cord-350019-4nlbu54e	416	13	is	be	VBZ
cord-350019-4nlbu54e	416	14	beginning	begin	VBG
cord-350019-4nlbu54e	416	15	to	to	TO
cord-350019-4nlbu54e	416	16	be	be	VB
cord-350019-4nlbu54e	416	17	appreciated	appreciate	VBN
cord-350019-4nlbu54e	416	18	.	.	.
cord-350019-4nlbu54e	417	1	A	a	DT
cord-350019-4nlbu54e	417	2	study	study	NN
cord-350019-4nlbu54e	417	3	by	by	IN
cord-350019-4nlbu54e	417	4	Winkler	Winkler	NNP
cord-350019-4nlbu54e	417	5	et	et	NNP
cord-350019-4nlbu54e	417	6	al	al	NNP
cord-350019-4nlbu54e	417	7	.	.	NNP
cord-350019-4nlbu54e	417	8	showed	show	VBD
cord-350019-4nlbu54e	417	9	that	that	IN
cord-350019-4nlbu54e	417	10	m6A	m6A	NNP
cord-350019-4nlbu54e	417	11	modification	modification	NN
cord-350019-4nlbu54e	417	12	controls	control	VBZ
cord-350019-4nlbu54e	417	13	the	the	DT
cord-350019-4nlbu54e	417	14	innate	innate	JJ
cord-350019-4nlbu54e	417	15	immune	immune	JJ
cord-350019-4nlbu54e	417	16	response	response	NN
cord-350019-4nlbu54e	417	17	to	to	IN
cord-350019-4nlbu54e	417	18	infection	infection	NN
cord-350019-4nlbu54e	417	19	by	by	IN
cord-350019-4nlbu54e	417	20	targeting	target	VBG
cord-350019-4nlbu54e	417	21	type	type	NN
cord-350019-4nlbu54e	417	22	I	-PRON-	PRP
cord-350019-4nlbu54e	417	23	interferons	interferon	NNS
cord-350019-4nlbu54e	417	24	[	[	-LRB-
cord-350019-4nlbu54e	417	25	267	267	CD
cord-350019-4nlbu54e	417	26	]	]	-RRB-
cord-350019-4nlbu54e	417	27	.	.	.
cord-350019-4nlbu54e	418	1	A	a	DT
cord-350019-4nlbu54e	418	2	few	few	JJ
cord-350019-4nlbu54e	418	3	recent	recent	JJ
cord-350019-4nlbu54e	418	4	studies	study	NNS
cord-350019-4nlbu54e	418	5	have	have	VBP
cord-350019-4nlbu54e	418	6	shown	show	VBN
cord-350019-4nlbu54e	418	7	that	that	IN
cord-350019-4nlbu54e	418	8	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	418	9	do	do	VBP
cord-350019-4nlbu54e	418	10	have	have	VB
cord-350019-4nlbu54e	418	11	RNA	RNA	NNP
cord-350019-4nlbu54e	418	12	modifications	modification	NNS
cord-350019-4nlbu54e	418	13	such	such	JJ
cord-350019-4nlbu54e	418	14	as	as	IN
cord-350019-4nlbu54e	418	15	MALAT1	MALAT1	NNP
cord-350019-4nlbu54e	418	16	containing	contain	VBG
cord-350019-4nlbu54e	418	17	m6A	m6a	NN
cord-350019-4nlbu54e	418	18	modifications	modification	NNS
cord-350019-4nlbu54e	418	19	[	[	-LRB-
cord-350019-4nlbu54e	418	20	268	268	CD
cord-350019-4nlbu54e	418	21	,	,	,
cord-350019-4nlbu54e	418	22	269	269	CD
cord-350019-4nlbu54e	418	23	]	]	-RRB-
cord-350019-4nlbu54e	418	24	,	,	,
cord-350019-4nlbu54e	418	25	HOTAIR	HOTAIR	NNP
cord-350019-4nlbu54e	418	26	containing	contain	VBG
cord-350019-4nlbu54e	418	27	m5C	m5C	NNP
cord-350019-4nlbu54e	418	28	and	and	CC
cord-350019-4nlbu54e	418	29	m6A	m6a	XX
cord-350019-4nlbu54e	418	30	[	[	-LRB-
cord-350019-4nlbu54e	418	31	270	270	CD
cord-350019-4nlbu54e	418	32	,	,	,
cord-350019-4nlbu54e	418	33	271	271	CD
cord-350019-4nlbu54e	418	34	]	]	-RRB-
cord-350019-4nlbu54e	418	35	and	and	CC
cord-350019-4nlbu54e	418	36	XIST	XIST	NNP
cord-350019-4nlbu54e	418	37	containing	contain	VBG
cord-350019-4nlbu54e	418	38	ψ	ψ	NN
cord-350019-4nlbu54e	418	39	,	,	,
cord-350019-4nlbu54e	418	40	m6A	m6A	NNP
cord-350019-4nlbu54e	418	41	and	and	CC
cord-350019-4nlbu54e	418	42	m5C	m5c	JJ
cord-350019-4nlbu54e	418	43	modifications	modification	NNS
cord-350019-4nlbu54e	418	44	[	[	-LRB-
cord-350019-4nlbu54e	418	45	269	269	CD
cord-350019-4nlbu54e	418	46	]	]	-RRB-
cord-350019-4nlbu54e	418	47	.	.	.
cord-350019-4nlbu54e	419	1	A	a	DT
cord-350019-4nlbu54e	419	2	study	study	NN
cord-350019-4nlbu54e	419	3	by	by	IN
cord-350019-4nlbu54e	419	4	Zhou	Zhou	NNP
cord-350019-4nlbu54e	419	5	et	et	NNP
cord-350019-4nlbu54e	419	6	al	al	NNP
cord-350019-4nlbu54e	419	7	.	.	NNP
cord-350019-4nlbu54e	419	8	showed	show	VBD
cord-350019-4nlbu54e	419	9	that	that	IN
cord-350019-4nlbu54e	419	10	the	the	DT
cord-350019-4nlbu54e	419	11	RNA	RNA	NNP
cord-350019-4nlbu54e	419	12	modification	modification	NN
cord-350019-4nlbu54e	419	13	,	,	,
cord-350019-4nlbu54e	419	14	m6A	m6A	NNP
cord-350019-4nlbu54e	419	15	,	,	,
cord-350019-4nlbu54e	419	16	acts	act	VBZ
cord-350019-4nlbu54e	419	17	as	as	IN
cord-350019-4nlbu54e	419	18	a	a	DT
cord-350019-4nlbu54e	419	19	structural	structural	JJ
cord-350019-4nlbu54e	419	20	'	'	``
cord-350019-4nlbu54e	419	21	switch	switch	NN
cord-350019-4nlbu54e	419	22	'	'	''
cord-350019-4nlbu54e	419	23	in	in	IN
cord-350019-4nlbu54e	419	24	Malat1	Malat1	NNP
cord-350019-4nlbu54e	419	25	.	.	.
cord-350019-4nlbu54e	420	1	When	when	WRB
cord-350019-4nlbu54e	420	2	there	there	EX
cord-350019-4nlbu54e	420	3	is	be	VBZ
cord-350019-4nlbu54e	420	4	a	a	DT
cord-350019-4nlbu54e	420	5	modification	modification	NN
cord-350019-4nlbu54e	420	6	at	at	IN
cord-350019-4nlbu54e	420	7	site	site	NN
cord-350019-4nlbu54e	420	8	2515	2515	CD
cord-350019-4nlbu54e	420	9	,	,	,
cord-350019-4nlbu54e	420	10	it	-PRON-	PRP
cord-350019-4nlbu54e	420	11	results	result	VBZ
cord-350019-4nlbu54e	420	12	in	in	IN
cord-350019-4nlbu54e	420	13	an	an	DT
cord-350019-4nlbu54e	420	14	increased	increase	VBN
cord-350019-4nlbu54e	420	15	ability	ability	NN
cord-350019-4nlbu54e	420	16	to	to	TO
cord-350019-4nlbu54e	420	17	bind	bind	VB
cord-350019-4nlbu54e	420	18	hnRNPG	hnrnpg	NN
cord-350019-4nlbu54e	420	19	,	,	,
cord-350019-4nlbu54e	420	20	while	while	IN
cord-350019-4nlbu54e	420	21	a	a	DT
cord-350019-4nlbu54e	420	22	modification	modification	NN
cord-350019-4nlbu54e	420	23	at	at	IN
cord-350019-4nlbu54e	420	24	2577	2577	CD
cord-350019-4nlbu54e	420	25	leads	lead	VBZ
cord-350019-4nlbu54e	420	26	to	to	IN
cord-350019-4nlbu54e	420	27	an	an	DT
cord-350019-4nlbu54e	420	28	increase	increase	NN
cord-350019-4nlbu54e	420	29	in	in	IN
cord-350019-4nlbu54e	420	30	binding	bind	VBG
cord-350019-4nlbu54e	420	31	to	to	IN
cord-350019-4nlbu54e	420	32	hnRNPC	hnrnpc	ADD
cord-350019-4nlbu54e	420	33	[	[	-LRB-
cord-350019-4nlbu54e	420	34	269	269	CD
cord-350019-4nlbu54e	420	35	]	]	-RRB-
cord-350019-4nlbu54e	420	36	.	.	.
cord-350019-4nlbu54e	421	1	In	in	IN
cord-350019-4nlbu54e	421	2	clinical	clinical	JJ
cord-350019-4nlbu54e	421	3	research	research	NN
cord-350019-4nlbu54e	421	4	,	,	,
cord-350019-4nlbu54e	421	5	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	421	6	RP11	RP11	NNP
cord-350019-4nlbu54e	421	7	-	-	HYPH
cord-350019-4nlbu54e	421	8	139J23.1	139J23.1	NNP
cord-350019-4nlbu54e	421	9	is	be	VBZ
cord-350019-4nlbu54e	421	10	highly	highly	RB
cord-350019-4nlbu54e	421	11	expressed	express	VBN
cord-350019-4nlbu54e	421	12	in	in	IN
cord-350019-4nlbu54e	421	13	colorectal	colorectal	JJ
cord-350019-4nlbu54e	421	14	cancer	cancer	NN
cord-350019-4nlbu54e	421	15	cells	cell	NNS
cord-350019-4nlbu54e	421	16	(	(	-LRB-
cord-350019-4nlbu54e	421	17	CRC	CRC	NNP
cord-350019-4nlbu54e	421	18	)	)	-RRB-
cord-350019-4nlbu54e	421	19	,	,	,
cord-350019-4nlbu54e	421	20	and	and	CC
cord-350019-4nlbu54e	421	21	this	this	DT
cord-350019-4nlbu54e	421	22	specific	specific	JJ
cord-350019-4nlbu54e	421	23	upregulation	upregulation	NN
cord-350019-4nlbu54e	421	24	was	be	VBD
cord-350019-4nlbu54e	421	25	controlled	control	VBN
cord-350019-4nlbu54e	421	26	by	by	IN
cord-350019-4nlbu54e	421	27	m6A	m6a	NN
cord-350019-4nlbu54e	421	28	methylation	methylation	NNS
cord-350019-4nlbu54e	421	29	[	[	-LRB-
cord-350019-4nlbu54e	421	30	272	272	CD
cord-350019-4nlbu54e	421	31	]	]	-RRB-
cord-350019-4nlbu54e	421	32	.	.	.
cord-350019-4nlbu54e	422	1	The	the	DT
cord-350019-4nlbu54e	422	2	study	study	NN
cord-350019-4nlbu54e	422	3	showed	show	VBD
cord-350019-4nlbu54e	422	4	that	that	IN
cord-350019-4nlbu54e	422	5	m6A	m6A	NNP
cord-350019-4nlbu54e	422	6	could	could	MD
cord-350019-4nlbu54e	422	7	regulate	regulate	VB
cord-350019-4nlbu54e	422	8	the	the	DT
cord-350019-4nlbu54e	422	9	lncRNA	lncrna	NN
cord-350019-4nlbu54e	422	10	,	,	,
cord-350019-4nlbu54e	422	11	which	which	WDT
cord-350019-4nlbu54e	422	12	in	in	IN
cord-350019-4nlbu54e	422	13	turn	turn	NN
cord-350019-4nlbu54e	422	14	triggered	trigger	VBD
cord-350019-4nlbu54e	422	15	the	the	DT
cord-350019-4nlbu54e	422	16	dissemination	dissemination	NN
cord-350019-4nlbu54e	422	17	of	of	IN
cord-350019-4nlbu54e	422	18	CRC	CRC	NNP
cord-350019-4nlbu54e	422	19	cells	cell	NNS
cord-350019-4nlbu54e	422	20	via	via	IN
cord-350019-4nlbu54e	422	21	post	post	JJ
cord-350019-4nlbu54e	422	22	-	-	JJ
cord-350019-4nlbu54e	422	23	translation	translation	JJ
cord-350019-4nlbu54e	422	24	upregulation	upregulation	NN
cord-350019-4nlbu54e	422	25	of	of	IN
cord-350019-4nlbu54e	422	26	the	the	DT
cord-350019-4nlbu54e	422	27	protein	protein	NN
cord-350019-4nlbu54e	422	28	Zeb1	Zeb1	NNP
cord-350019-4nlbu54e	422	29	.	.	.
cord-350019-4nlbu54e	423	1	This	this	DT
cord-350019-4nlbu54e	423	2	novel	novel	JJ
cord-350019-4nlbu54e	423	3	study	study	NN
cord-350019-4nlbu54e	423	4	,	,	,
cord-350019-4nlbu54e	423	5	connecting	connect	VBG
cord-350019-4nlbu54e	423	6	the	the	DT
cord-350019-4nlbu54e	423	7	interplay	interplay	NN
cord-350019-4nlbu54e	423	8	of	of	IN
cord-350019-4nlbu54e	423	9	RNA	RNA	NNP
cord-350019-4nlbu54e	423	10	modifications	modification	NNS
cord-350019-4nlbu54e	423	11	and	and	CC
cord-350019-4nlbu54e	423	12	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	423	13	,	,	,
cord-350019-4nlbu54e	423	14	has	have	VBZ
cord-350019-4nlbu54e	423	15	paved	pave	VBN
cord-350019-4nlbu54e	423	16	the	the	DT
cord-350019-4nlbu54e	423	17	way	way	NN
cord-350019-4nlbu54e	423	18	for	for	IN
cord-350019-4nlbu54e	423	19	a	a	DT
cord-350019-4nlbu54e	423	20	novel	novel	JJ
cord-350019-4nlbu54e	423	21	predictive	predictive	JJ
cord-350019-4nlbu54e	423	22	biomarker	biomarker	NN
cord-350019-4nlbu54e	423	23	or	or	CC
cord-350019-4nlbu54e	423	24	therapeutic	therapeutic	JJ
cord-350019-4nlbu54e	423	25	target	target	NN
cord-350019-4nlbu54e	423	26	in	in	IN
cord-350019-4nlbu54e	423	27	CRC	CRC	NNP
cord-350019-4nlbu54e	423	28	[	[	-LRB-
cord-350019-4nlbu54e	423	29	272	272	CD
cord-350019-4nlbu54e	423	30	]	]	-RRB-
cord-350019-4nlbu54e	423	31	.	.	.
cord-350019-4nlbu54e	424	1	There	there	EX
cord-350019-4nlbu54e	424	2	are	be	VBP
cord-350019-4nlbu54e	424	3	over	over	IN
cord-350019-4nlbu54e	424	4	160	160	CD
cord-350019-4nlbu54e	424	5	identified	identify	VBN
cord-350019-4nlbu54e	424	6	RNA	RNA	NNP
cord-350019-4nlbu54e	424	7	modifications	modification	NNS
cord-350019-4nlbu54e	424	8	,	,	,
cord-350019-4nlbu54e	424	9	while	while	IN
cord-350019-4nlbu54e	424	10	only	only	RB
cord-350019-4nlbu54e	424	11	a	a	DT
cord-350019-4nlbu54e	424	12	few	few	JJ
cord-350019-4nlbu54e	424	13	have	have	VBP
cord-350019-4nlbu54e	424	14	been	be	VBN
cord-350019-4nlbu54e	424	15	studied	study	VBN
cord-350019-4nlbu54e	424	16	to	to	IN
cord-350019-4nlbu54e	424	17	any	any	DT
cord-350019-4nlbu54e	424	18	extent	extent	NN
cord-350019-4nlbu54e	424	19	[	[	-LRB-
cord-350019-4nlbu54e	424	20	273	273	CD
cord-350019-4nlbu54e	424	21	]	]	-RRB-
cord-350019-4nlbu54e	424	22	.	.	.
cord-350019-4nlbu54e	425	1	Of	of	IN
cord-350019-4nlbu54e	425	2	these	these	DT
cord-350019-4nlbu54e	425	3	RNA	RNA	NNP
cord-350019-4nlbu54e	425	4	modifications	modification	NNS
cord-350019-4nlbu54e	425	5	,	,	,
cord-350019-4nlbu54e	425	6	the	the	DT
cord-350019-4nlbu54e	425	7	way	way	NN
cord-350019-4nlbu54e	425	8	they	-PRON-	PRP
cord-350019-4nlbu54e	425	9	are	be	VBP
cord-350019-4nlbu54e	425	10	enriched	enrich	VBN
cord-350019-4nlbu54e	425	11	for	for	IN
cord-350019-4nlbu54e	425	12	in	in	IN
cord-350019-4nlbu54e	425	13	analysis	analysis	NN
cord-350019-4nlbu54e	425	14	is	be	VBZ
cord-350019-4nlbu54e	425	15	through	through	IN
cord-350019-4nlbu54e	425	16	an	an	DT
cord-350019-4nlbu54e	425	17	assortment	assortment	NN
cord-350019-4nlbu54e	425	18	of	of	IN
cord-350019-4nlbu54e	425	19	techniques	technique	NNS
cord-350019-4nlbu54e	425	20	including	include	VBG
cord-350019-4nlbu54e	425	21	methylated	methylate	VBN
cord-350019-4nlbu54e	425	22	RNA	rna	NN
cord-350019-4nlbu54e	425	23	immunoprecipitation	immunoprecipitation	NN
cord-350019-4nlbu54e	425	24	(	(	-LRB-
cord-350019-4nlbu54e	425	25	MeRIP	MeRIP	NNP
cord-350019-4nlbu54e	425	26	)	)	-RRB-
cord-350019-4nlbu54e	425	27	,	,	,
cord-350019-4nlbu54e	425	28	MeRIP	MeRIP	NNP
cord-350019-4nlbu54e	425	29	-	-	HYPH
cord-350019-4nlbu54e	425	30	iCLIP	iCLIP	NNP
cord-350019-4nlbu54e	425	31	(	(	-LRB-
cord-350019-4nlbu54e	425	32	crosslinking	crosslinking	NN
cord-350019-4nlbu54e	425	33	and	and	CC
cord-350019-4nlbu54e	425	34	immunoprecipitation	immunoprecipitation	NN
cord-350019-4nlbu54e	425	35	)	)	-RRB-
cord-350019-4nlbu54e	425	36	,	,	,
cord-350019-4nlbu54e	425	37	Suicide	suicide	NN
cord-350019-4nlbu54e	425	38	enzyme	enzyme	NN
cord-350019-4nlbu54e	425	39	trap	trap	NN
cord-350019-4nlbu54e	425	40	and	and	CC
cord-350019-4nlbu54e	425	41	Clickable	clickable	JJ
cord-350019-4nlbu54e	425	42	chemicals	chemical	NNS
cord-350019-4nlbu54e	425	43	(	(	-LRB-
cord-350019-4nlbu54e	425	44	Reviewed	review	VBN
cord-350019-4nlbu54e	425	45	in	in	IN
cord-350019-4nlbu54e	425	46	[	[	-LRB-
cord-350019-4nlbu54e	425	47	274	274	CD
cord-350019-4nlbu54e	425	48	]	]	-RRB-
cord-350019-4nlbu54e	425	49	)	)	-RRB-
cord-350019-4nlbu54e	425	50	.	.	.
cord-350019-4nlbu54e	426	1	These	these	DT
cord-350019-4nlbu54e	426	2	techniques	technique	NNS
cord-350019-4nlbu54e	426	3	have	have	VBP
cord-350019-4nlbu54e	426	4	many	many	JJ
cord-350019-4nlbu54e	426	5	limitations	limitation	NNS
cord-350019-4nlbu54e	426	6	and	and	CC
cord-350019-4nlbu54e	426	7	biases	bias	NNS
cord-350019-4nlbu54e	426	8	,	,	,
cord-350019-4nlbu54e	426	9	but	but	CC
cord-350019-4nlbu54e	426	10	hopefully	hopefully	RB
cord-350019-4nlbu54e	426	11	,	,	,
cord-350019-4nlbu54e	426	12	future	future	JJ
cord-350019-4nlbu54e	426	13	studies	study	NNS
cord-350019-4nlbu54e	426	14	using	use	VBG
cord-350019-4nlbu54e	426	15	direct	direct	JJ
cord-350019-4nlbu54e	426	16	RNA	RNA	NNP
cord-350019-4nlbu54e	426	17	nanopore	nanopore	NN
cord-350019-4nlbu54e	426	18	sequencing	sequencing	NN
cord-350019-4nlbu54e	426	19	will	will	MD
cord-350019-4nlbu54e	426	20	overcome	overcome	VB
cord-350019-4nlbu54e	426	21	all	all	PDT
cord-350019-4nlbu54e	426	22	these	these	DT
cord-350019-4nlbu54e	426	23	pitfalls	pitfall	NNS
cord-350019-4nlbu54e	426	24	.	.	.
cord-350019-4nlbu54e	427	1	In	in	IN
cord-350019-4nlbu54e	427	2	a	a	DT
cord-350019-4nlbu54e	427	3	recent	recent	JJ
cord-350019-4nlbu54e	427	4	study	study	NN
cord-350019-4nlbu54e	427	5	,	,	,
cord-350019-4nlbu54e	427	6	direct	direct	JJ
cord-350019-4nlbu54e	427	7	RNA	RNA	NNP
cord-350019-4nlbu54e	427	8	sequencing	sequencing	NN
cord-350019-4nlbu54e	427	9	using	use	VBG
cord-350019-4nlbu54e	427	10	nanopore	nanopore	NNP
cord-350019-4nlbu54e	427	11	technology	technology	NN
cord-350019-4nlbu54e	427	12	showed	show	VBD
cord-350019-4nlbu54e	427	13	detection	detection	NN
cord-350019-4nlbu54e	427	14	of	of	IN
cord-350019-4nlbu54e	427	15	m6A	m6a	NN
cord-350019-4nlbu54e	427	16	modifications	modification	NNS
cord-350019-4nlbu54e	427	17	with	with	IN
cord-350019-4nlbu54e	427	18	a	a	DT
cord-350019-4nlbu54e	427	19	97	97	CD
cord-350019-4nlbu54e	427	20	%	%	NN
cord-350019-4nlbu54e	427	21	accuracy	accuracy	NN
cord-350019-4nlbu54e	427	22	with	with	IN
cord-350019-4nlbu54e	427	23	the	the	DT
cord-350019-4nlbu54e	427	24	design	design	NN
cord-350019-4nlbu54e	427	25	of	of	IN
cord-350019-4nlbu54e	427	26	synthetic	synthetic	JJ
cord-350019-4nlbu54e	427	27	sequences	sequence	NNS
cord-350019-4nlbu54e	427	28	[	[	-LRB-
cord-350019-4nlbu54e	427	29	275	275	CD
cord-350019-4nlbu54e	427	30	]	]	-RRB-
cord-350019-4nlbu54e	427	31	.	.	.
cord-350019-4nlbu54e	428	1	As	as	IN
cord-350019-4nlbu54e	428	2	the	the	DT
cord-350019-4nlbu54e	428	3	performance	performance	NN
cord-350019-4nlbu54e	428	4	of	of	IN
cord-350019-4nlbu54e	428	5	the	the	DT
cord-350019-4nlbu54e	428	6	algorithm	algorithm	NN
cord-350019-4nlbu54e	428	7	increases	increase	VBZ
cord-350019-4nlbu54e	428	8	,	,	,
cord-350019-4nlbu54e	428	9	use	use	NN
cord-350019-4nlbu54e	428	10	of	of	IN
cord-350019-4nlbu54e	428	11	this	this	DT
cord-350019-4nlbu54e	428	12	tool	tool	NN
cord-350019-4nlbu54e	428	13	will	will	MD
cord-350019-4nlbu54e	428	14	be	be	VB
cord-350019-4nlbu54e	428	15	extremely	extremely	RB
cord-350019-4nlbu54e	428	16	insightful	insightful	JJ
cord-350019-4nlbu54e	428	17	when	when	WRB
cord-350019-4nlbu54e	428	18	The	the	DT
cord-350019-4nlbu54e	428	19	flow	flow	NN
cord-350019-4nlbu54e	428	20	-	-	HYPH
cord-350019-4nlbu54e	428	21	chart	chart	NN
cord-350019-4nlbu54e	428	22	provides	provide	VBZ
cord-350019-4nlbu54e	428	23	a	a	DT
cord-350019-4nlbu54e	428	24	"	"	``
cord-350019-4nlbu54e	428	25	beginning	beginning	NN
cord-350019-4nlbu54e	428	26	to	to	TO
cord-350019-4nlbu54e	428	27	end	end	VB
cord-350019-4nlbu54e	428	28	"	"	``
cord-350019-4nlbu54e	428	29	guide	guide	NN
cord-350019-4nlbu54e	428	30	to	to	TO
cord-350019-4nlbu54e	428	31	study	study	VB
cord-350019-4nlbu54e	428	32	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	428	33	.	.	.
cord-350019-4nlbu54e	429	1	Not	not	RB
cord-350019-4nlbu54e	429	2	all	all	DT
cord-350019-4nlbu54e	429	3	suggested	suggest	VBN
cord-350019-4nlbu54e	429	4	databases	database	NNS
cord-350019-4nlbu54e	429	5	will	will	MD
cord-350019-4nlbu54e	429	6	be	be	VB
cord-350019-4nlbu54e	429	7	appropriate	appropriate	JJ
cord-350019-4nlbu54e	429	8	for	for	IN
cord-350019-4nlbu54e	429	9	all	all	DT
cord-350019-4nlbu54e	429	10	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	429	11	being	be	VBG
cord-350019-4nlbu54e	429	12	studied	study	VBN
cord-350019-4nlbu54e	429	13	.	.	.
cord-350019-4nlbu54e	430	1	A.	A.	NNP
cord-350019-4nlbu54e	430	2	Selection	selection	NN
cord-350019-4nlbu54e	430	3	of	of	IN
cord-350019-4nlbu54e	430	4	candidate	candidate	NN
cord-350019-4nlbu54e	430	5	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	430	6	should	should	MD
cord-350019-4nlbu54e	430	7	factor	factor	VB
cord-350019-4nlbu54e	430	8	in	in	IN
cord-350019-4nlbu54e	430	9	changes	change	NNS
cord-350019-4nlbu54e	430	10	in	in	IN
cord-350019-4nlbu54e	430	11	expression	expression	NN
cord-350019-4nlbu54e	430	12	,	,	,
cord-350019-4nlbu54e	430	13	type	type	NN
cord-350019-4nlbu54e	430	14	of	of	IN
cord-350019-4nlbu54e	430	15	lncRNA	lncrna	NN
cord-350019-4nlbu54e	430	16	and	and	CC
cord-350019-4nlbu54e	430	17	nearby	nearby	JJ
cord-350019-4nlbu54e	430	18	coding	code	VBG
cord-350019-4nlbu54e	430	19	genes	gene	NNS
cord-350019-4nlbu54e	430	20	.	.	.
cord-350019-4nlbu54e	431	1	B.	B.	NNP
cord-350019-4nlbu54e	431	2	Bioinformatic	Bioinformatic	NNP
cord-350019-4nlbu54e	431	3	characterization	characterization	NN
cord-350019-4nlbu54e	431	4	of	of	IN
cord-350019-4nlbu54e	431	5	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	431	6	can	can	MD
cord-350019-4nlbu54e	431	7	be	be	VB
cord-350019-4nlbu54e	431	8	done	do	VBN
cord-350019-4nlbu54e	431	9	using	use	VBG
cord-350019-4nlbu54e	431	10	a	a	DT
cord-350019-4nlbu54e	431	11	variety	variety	NN
cord-350019-4nlbu54e	431	12	of	of	IN
cord-350019-4nlbu54e	431	13	online	online	JJ
cord-350019-4nlbu54e	431	14	databases	database	NNS
cord-350019-4nlbu54e	431	15	including	include	VBG
cord-350019-4nlbu54e	431	16	:	:	:
cord-350019-4nlbu54e	431	17	LNCipedia	LNCipedia	NNP
cord-350019-4nlbu54e	431	18	to	to	TO
cord-350019-4nlbu54e	431	19	assess	assess	VB
cord-350019-4nlbu54e	431	20	conservation	conservation	NN
cord-350019-4nlbu54e	431	21	or	or	CC
cord-350019-4nlbu54e	431	22	using	use	VBG
cord-350019-4nlbu54e	431	23	the	the	DT
cord-350019-4nlbu54e	431	24	Mouse	Mouse	NNP
cord-350019-4nlbu54e	431	25	Cell	Cell	NNP
cord-350019-4nlbu54e	431	26	Atlas	Atlas	NNP
cord-350019-4nlbu54e	431	27	(	(	-LRB-
cord-350019-4nlbu54e	431	28	MCA	MCA	NNP
cord-350019-4nlbu54e	431	29	)	)	-RRB-
cord-350019-4nlbu54e	431	30	to	to	TO
cord-350019-4nlbu54e	431	31	assess	assess	VB
cord-350019-4nlbu54e	431	32	tissue	tissue	NN
cord-350019-4nlbu54e	431	33	specific	specific	JJ
cord-350019-4nlbu54e	431	34	expression	expression	NN
cord-350019-4nlbu54e	431	35	.	.	.
cord-350019-4nlbu54e	432	1	C.	C.	NNP
cord-350019-4nlbu54e	432	2	Expression	Expression	NNP
cord-350019-4nlbu54e	432	3	validation	validation	NN
cord-350019-4nlbu54e	432	4	:	:	:
cord-350019-4nlbu54e	433	1	This	this	DT
cord-350019-4nlbu54e	433	2	includes	include	VBZ
cord-350019-4nlbu54e	433	3	validation	validation	NN
cord-350019-4nlbu54e	433	4	of	of	IN
cord-350019-4nlbu54e	433	5	expression	expression	NN
cord-350019-4nlbu54e	433	6	and	and	CC
cord-350019-4nlbu54e	433	7	confirming	confirm	VBG
cord-350019-4nlbu54e	433	8	that	that	IN
cord-350019-4nlbu54e	433	9	the	the	DT
cord-350019-4nlbu54e	433	10	lncRNA	lncrna	NN
cord-350019-4nlbu54e	433	11	is	be	VBZ
cord-350019-4nlbu54e	433	12	in	in	IN
cord-350019-4nlbu54e	433	13	-	-	HYPH
cord-350019-4nlbu54e	433	14	fact	fact	NN
cord-350019-4nlbu54e	433	15	non	non	JJ
cord-350019-4nlbu54e	433	16	-	-	JJ
cord-350019-4nlbu54e	433	17	protein	protein	JJ
cord-350019-4nlbu54e	433	18	coding	coding	NN
cord-350019-4nlbu54e	433	19	.	.	.
cord-350019-4nlbu54e	434	1	D.	D.	NNP
cord-350019-4nlbu54e	435	1	Functional	functional	JJ
cord-350019-4nlbu54e	435	2	validation	validation	NN
cord-350019-4nlbu54e	435	3	dives	dive	VBZ
cord-350019-4nlbu54e	435	4	into	into	IN
cord-350019-4nlbu54e	435	5	the	the	DT
cord-350019-4nlbu54e	435	6	final	final	JJ
cord-350019-4nlbu54e	435	7	stage	stage	NN
cord-350019-4nlbu54e	435	8	of	of	IN
cord-350019-4nlbu54e	435	9	mechanistic	mechanistic	JJ
cord-350019-4nlbu54e	435	10	characterization	characterization	NN
cord-350019-4nlbu54e	435	11	of	of	IN
cord-350019-4nlbu54e	435	12	a	a	DT
cord-350019-4nlbu54e	435	13	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	435	14	,	,	,
cord-350019-4nlbu54e	435	15	which	which	WDT
cord-350019-4nlbu54e	435	16	involved	involve	VBD
cord-350019-4nlbu54e	435	17	manipulating	manipulate	VBG
cord-350019-4nlbu54e	435	18	its	-PRON-	PRP$
cord-350019-4nlbu54e	435	19	expression	expression	NN
cord-350019-4nlbu54e	435	20	,	,	,
cord-350019-4nlbu54e	435	21	as	as	RB
cord-350019-4nlbu54e	435	22	well	well	RB
cord-350019-4nlbu54e	435	23	as	as	IN
cord-350019-4nlbu54e	435	24	uncovering	uncover	VBG
cord-350019-4nlbu54e	435	25	the	the	DT
cord-350019-4nlbu54e	435	26	specific	specific	JJ
cord-350019-4nlbu54e	435	27	cis	ci	NNS
cord-350019-4nlbu54e	435	28	-	-	HYPH
cord-350019-4nlbu54e	435	29	elements	element	NNS
cord-350019-4nlbu54e	435	30	within	within	IN
cord-350019-4nlbu54e	435	31	the	the	DT
cord-350019-4nlbu54e	435	32	transcript	transcript	NN
cord-350019-4nlbu54e	435	33	important	important	JJ
cord-350019-4nlbu54e	435	34	for	for	IN
cord-350019-4nlbu54e	435	35	its	-PRON-	PRP$
cord-350019-4nlbu54e	435	36	function	function	NN
cord-350019-4nlbu54e	435	37	.	.	.
cord-350019-4nlbu54e	436	1	analyzing	analyze	VBG
cord-350019-4nlbu54e	436	2	myeloid	myeloid	JJ
cord-350019-4nlbu54e	436	3	or	or	CC
cord-350019-4nlbu54e	436	4	lymphoid	lymphoid	JJ
cord-350019-4nlbu54e	436	5	primary	primary	JJ
cord-350019-4nlbu54e	436	6	cells	cell	NNS
cord-350019-4nlbu54e	436	7	with	with	IN
cord-350019-4nlbu54e	436	8	and	and	CC
cord-350019-4nlbu54e	436	9	without	without	IN
cord-350019-4nlbu54e	436	10	a	a	DT
cord-350019-4nlbu54e	436	11	treatment	treatment	NN
cord-350019-4nlbu54e	436	12	to	to	TO
cord-350019-4nlbu54e	436	13	understand	understand	VB
cord-350019-4nlbu54e	436	14	how	how	WRB
cord-350019-4nlbu54e	436	15	RNA	RNA	NNP
cord-350019-4nlbu54e	436	16	modifications	modification	NNS
cord-350019-4nlbu54e	436	17	are	be	VBP
cord-350019-4nlbu54e	436	18	regulated	regulate	VBN
cord-350019-4nlbu54e	436	19	in	in	IN
cord-350019-4nlbu54e	436	20	innate	innate	JJ
cord-350019-4nlbu54e	436	21	immunity	immunity	NN
cord-350019-4nlbu54e	436	22	and	and	CC
cord-350019-4nlbu54e	436	23	specifically	specifically	RB
cord-350019-4nlbu54e	436	24	as	as	IN
cord-350019-4nlbu54e	436	25	it	-PRON-	PRP
cord-350019-4nlbu54e	436	26	relates	relate	VBZ
cord-350019-4nlbu54e	436	27	to	to	IN
cord-350019-4nlbu54e	436	28	our	-PRON-	PRP$
cord-350019-4nlbu54e	436	29	long	long	JJ
cord-350019-4nlbu54e	436	30	noncoding	noncoding	JJ
cord-350019-4nlbu54e	436	31	transcriptome	transcriptome	NN
cord-350019-4nlbu54e	436	32	.	.	.
cord-350019-4nlbu54e	437	1	LncRNAs	LncRNAs	NNP
cord-350019-4nlbu54e	437	2	,	,	,
cord-350019-4nlbu54e	437	3	including	include	VBG
cord-350019-4nlbu54e	437	4	XIST	XIST	NNP
cord-350019-4nlbu54e	437	5	and	and	CC
cord-350019-4nlbu54e	437	6	H19	H19	NNP
cord-350019-4nlbu54e	437	7	,	,	,
cord-350019-4nlbu54e	437	8	have	have	VBP
cord-350019-4nlbu54e	437	9	been	be	VBN
cord-350019-4nlbu54e	437	10	studied	study	VBN
cord-350019-4nlbu54e	437	11	intensely	intensely	RB
cord-350019-4nlbu54e	437	12	for	for	IN
cord-350019-4nlbu54e	437	13	decades	decade	NNS
cord-350019-4nlbu54e	437	14	[	[	-LRB-
cord-350019-4nlbu54e	437	15	275	275	CD
cord-350019-4nlbu54e	437	16	,	,	,
cord-350019-4nlbu54e	437	17	276	276	CD
cord-350019-4nlbu54e	437	18	]	]	-RRB-
cord-350019-4nlbu54e	437	19	.	.	.
cord-350019-4nlbu54e	438	1	At	at	IN
cord-350019-4nlbu54e	438	2	the	the	DT
cord-350019-4nlbu54e	438	3	time	time	NN
cord-350019-4nlbu54e	438	4	we	-PRON-	PRP
cord-350019-4nlbu54e	438	5	had	have	VBD
cord-350019-4nlbu54e	438	6	no	no	DT
cord-350019-4nlbu54e	438	7	idea	idea	NN
cord-350019-4nlbu54e	438	8	that	that	IN
cord-350019-4nlbu54e	438	9	these	these	DT
cord-350019-4nlbu54e	438	10	genes	gene	NNS
cord-350019-4nlbu54e	438	11	would	would	MD
cord-350019-4nlbu54e	438	12	represent	represent	VB
cord-350019-4nlbu54e	438	13	the	the	DT
cord-350019-4nlbu54e	438	14	largest	large	JJS
cord-350019-4nlbu54e	438	15	family	family	NN
cord-350019-4nlbu54e	438	16	of	of	IN
cord-350019-4nlbu54e	438	17	RNA	RNA	NNP
cord-350019-4nlbu54e	438	18	genes	gene	NNS
cord-350019-4nlbu54e	438	19	produced	produce	VBN
cord-350019-4nlbu54e	438	20	in	in	IN
cord-350019-4nlbu54e	438	21	the	the	DT
cord-350019-4nlbu54e	438	22	genome	genome	NN
cord-350019-4nlbu54e	438	23	.	.	.
cord-350019-4nlbu54e	439	1	As	as	IN
cord-350019-4nlbu54e	439	2	Louis	Louis	NNP
cord-350019-4nlbu54e	439	3	Pasteur	Pasteur	NNP
cord-350019-4nlbu54e	439	4	once	once	RB
cord-350019-4nlbu54e	439	5	said	say	VBD
cord-350019-4nlbu54e	439	6	,	,	,
cord-350019-4nlbu54e	439	7	"	"	``
cord-350019-4nlbu54e	439	8	Chance	chance	VB
cord-350019-4nlbu54e	439	9	favors	favor	VBZ
cord-350019-4nlbu54e	439	10	the	the	DT
cord-350019-4nlbu54e	439	11	prepared	prepared	JJ
cord-350019-4nlbu54e	439	12	mind	mind	NN
cord-350019-4nlbu54e	439	13	,	,	,
cord-350019-4nlbu54e	439	14	"	"	''
cord-350019-4nlbu54e	439	15	and	and	CC
cord-350019-4nlbu54e	439	16	this	this	DT
cord-350019-4nlbu54e	439	17	is	be	VBZ
cord-350019-4nlbu54e	439	18	especially	especially	RB
cord-350019-4nlbu54e	439	19	true	true	JJ
cord-350019-4nlbu54e	439	20	following	follow	VBG
cord-350019-4nlbu54e	439	21	the	the	DT
cord-350019-4nlbu54e	439	22	development	development	NN
cord-350019-4nlbu54e	439	23	of	of	IN
cord-350019-4nlbu54e	439	24	next	next	JJ
cord-350019-4nlbu54e	439	25	-	-	HYPH
cord-350019-4nlbu54e	439	26	generation	generation	NN
cord-350019-4nlbu54e	439	27	sequencing	sequencing	NN
cord-350019-4nlbu54e	439	28	.	.	.
cord-350019-4nlbu54e	440	1	RNA	rna	NN
cord-350019-4nlbu54e	440	2	-	-	HYPH
cord-350019-4nlbu54e	440	3	sequencing	sequencing	NN
cord-350019-4nlbu54e	440	4	provided	provide	VBD
cord-350019-4nlbu54e	440	5	an	an	DT
cord-350019-4nlbu54e	440	6	unprecedented	unprecedented	JJ
cord-350019-4nlbu54e	440	7	insight	insight	NN
cord-350019-4nlbu54e	440	8	into	into	IN
cord-350019-4nlbu54e	440	9	the	the	DT
cord-350019-4nlbu54e	440	10	human	human	JJ
cord-350019-4nlbu54e	440	11	genome	genome	NN
cord-350019-4nlbu54e	440	12	.	.	.
cord-350019-4nlbu54e	441	1	We	-PRON-	PRP
cord-350019-4nlbu54e	441	2	did	do	VBD
cord-350019-4nlbu54e	441	3	not	not	RB
cord-350019-4nlbu54e	441	4	identify	identify	VB
cord-350019-4nlbu54e	441	5	new	new	JJ
cord-350019-4nlbu54e	441	6	proteins	protein	NNS
cord-350019-4nlbu54e	441	7	,	,	,
cord-350019-4nlbu54e	441	8	instead	instead	RB
cord-350019-4nlbu54e	441	9	we	-PRON-	PRP
cord-350019-4nlbu54e	441	10	found	find	VBD
cord-350019-4nlbu54e	441	11	a	a	DT
cord-350019-4nlbu54e	441	12	wealth	wealth	NN
cord-350019-4nlbu54e	441	13	of	of	IN
cord-350019-4nlbu54e	441	14	noncoding	noncoding	JJ
cord-350019-4nlbu54e	441	15	RNA	RNA	NNP
cord-350019-4nlbu54e	441	16	transcripts	transcript	NNS
cord-350019-4nlbu54e	441	17	.	.	.
cord-350019-4nlbu54e	442	1	The	the	DT
cord-350019-4nlbu54e	442	2	lncRNA	lncrna	NN
cord-350019-4nlbu54e	442	3	field	field	NN
cord-350019-4nlbu54e	442	4	is	be	VBZ
cord-350019-4nlbu54e	442	5	growing	grow	VBG
cord-350019-4nlbu54e	442	6	at	at	IN
cord-350019-4nlbu54e	442	7	a	a	DT
cord-350019-4nlbu54e	442	8	blistering	blistering	JJ
cord-350019-4nlbu54e	442	9	pace	pace	NN
cord-350019-4nlbu54e	442	10	with	with	IN
cord-350019-4nlbu54e	442	11	labs	lab	NNS
cord-350019-4nlbu54e	442	12	from	from	IN
cord-350019-4nlbu54e	442	13	all	all	DT
cord-350019-4nlbu54e	442	14	aspects	aspect	NNS
cord-350019-4nlbu54e	442	15	of	of	IN
cord-350019-4nlbu54e	442	16	biology	biology	NN
cord-350019-4nlbu54e	442	17	,	,	,
cord-350019-4nlbu54e	442	18	and	and	CC
cord-350019-4nlbu54e	442	19	now	now	RB
cord-350019-4nlbu54e	442	20	immunology	immunology	NN
cord-350019-4nlbu54e	442	21	branching	branch	VBG
cord-350019-4nlbu54e	442	22	out	out	RP
cord-350019-4nlbu54e	442	23	to	to	TO
cord-350019-4nlbu54e	442	24	include	include	VB
cord-350019-4nlbu54e	442	25	questions	question	NNS
cord-350019-4nlbu54e	442	26	about	about	IN
cord-350019-4nlbu54e	442	27	the	the	DT
cord-350019-4nlbu54e	442	28	regulatory	regulatory	JJ
cord-350019-4nlbu54e	442	29	impact	impact	NN
cord-350019-4nlbu54e	442	30	of	of	IN
cord-350019-4nlbu54e	442	31	these	these	DT
cord-350019-4nlbu54e	442	32	pervasive	pervasive	JJ
cord-350019-4nlbu54e	442	33	long	long	JJ
cord-350019-4nlbu54e	442	34	noncoding	noncoding	JJ
cord-350019-4nlbu54e	442	35	gene	gene	NN
cord-350019-4nlbu54e	442	36	species	specie	NNS
cord-350019-4nlbu54e	442	37	.	.	.
cord-350019-4nlbu54e	443	1	As	as	IN
cord-350019-4nlbu54e	443	2	detailed	detail	VBN
cord-350019-4nlbu54e	443	3	in	in	IN
cord-350019-4nlbu54e	443	4	this	this	DT
cord-350019-4nlbu54e	443	5	review	review	NN
cord-350019-4nlbu54e	443	6	,	,	,
cord-350019-4nlbu54e	443	7	there	there	EX
cord-350019-4nlbu54e	443	8	are	be	VBP
cord-350019-4nlbu54e	443	9	many	many	JJ
cord-350019-4nlbu54e	443	10	publicly	publicly	RB
cord-350019-4nlbu54e	443	11	available	available	JJ
cord-350019-4nlbu54e	443	12	datasets	dataset	NNS
cord-350019-4nlbu54e	443	13	and	and	CC
cord-350019-4nlbu54e	443	14	web	web	NN
cord-350019-4nlbu54e	443	15	servers	server	NNS
cord-350019-4nlbu54e	443	16	that	that	WDT
cord-350019-4nlbu54e	443	17	will	will	MD
cord-350019-4nlbu54e	443	18	streamline	streamline	VB
cord-350019-4nlbu54e	443	19	how	how	WRB
cord-350019-4nlbu54e	443	20	to	to	TO
cord-350019-4nlbu54e	443	21	begin	begin	VB
cord-350019-4nlbu54e	443	22	a	a	DT
cord-350019-4nlbu54e	443	23	lncRNA	lncrna	NN
cord-350019-4nlbu54e	443	24	project	project	NN
cord-350019-4nlbu54e	443	25	,	,	,
cord-350019-4nlbu54e	443	26	from	from	IN
cord-350019-4nlbu54e	443	27	how	how	WRB
cord-350019-4nlbu54e	443	28	to	to	TO
cord-350019-4nlbu54e	443	29	pick	pick	VB
cord-350019-4nlbu54e	443	30	a	a	DT
cord-350019-4nlbu54e	443	31	lncRNA	lncrna	NN
cord-350019-4nlbu54e	443	32	candidate	candidate	NN
cord-350019-4nlbu54e	443	33	by	by	IN
cord-350019-4nlbu54e	443	34	interrogating	interrogate	VBG
cord-350019-4nlbu54e	443	35	published	publish	VBN
cord-350019-4nlbu54e	443	36	RNA	RNA	NNP
cord-350019-4nlbu54e	443	37	-	-	HYPH
cord-350019-4nlbu54e	443	38	sequencing	sequence	VBG
cord-350019-4nlbu54e	443	39	data	datum	NNS
cord-350019-4nlbu54e	443	40	,	,	,
cord-350019-4nlbu54e	443	41	to	to	TO
cord-350019-4nlbu54e	443	42	determine	determine	VB
cord-350019-4nlbu54e	443	43	the	the	DT
cord-350019-4nlbu54e	443	44	best	good	JJS
cord-350019-4nlbu54e	443	45	tools	tool	NNS
cord-350019-4nlbu54e	443	46	to	to	TO
cord-350019-4nlbu54e	443	47	use	use	VB
cord-350019-4nlbu54e	443	48	to	to	TO
cord-350019-4nlbu54e	443	49	study	study	VB
cord-350019-4nlbu54e	443	50	the	the	DT
cord-350019-4nlbu54e	443	51	function	function	NN
cord-350019-4nlbu54e	443	52	and	and	CC
cord-350019-4nlbu54e	443	53	mechanism	mechanism	NN
cord-350019-4nlbu54e	443	54	of	of	IN
cord-350019-4nlbu54e	443	55	a	a	DT
cord-350019-4nlbu54e	443	56	candidate	candidate	NN
cord-350019-4nlbu54e	444	1	(	(	-LRB-
cord-350019-4nlbu54e	444	2	Fig	Fig	NNP
cord-350019-4nlbu54e	444	3	.	.	NNP
cord-350019-4nlbu54e	444	4	4	4	CD
cord-350019-4nlbu54e	444	5	)	)	-RRB-
cord-350019-4nlbu54e	444	6	.	.	.
cord-350019-4nlbu54e	445	1	Since	since	IN
cord-350019-4nlbu54e	445	2	this	this	DT
cord-350019-4nlbu54e	445	3	field	field	NN
cord-350019-4nlbu54e	445	4	is	be	VBZ
cord-350019-4nlbu54e	445	5	still	still	RB
cord-350019-4nlbu54e	445	6	at	at	IN
cord-350019-4nlbu54e	445	7	an	an	DT
cord-350019-4nlbu54e	445	8	early	early	JJ
cord-350019-4nlbu54e	445	9	stage	stage	NN
cord-350019-4nlbu54e	445	10	in	in	IN
cord-350019-4nlbu54e	445	11	its	-PRON-	PRP$
cord-350019-4nlbu54e	445	12	development	development	NN
cord-350019-4nlbu54e	445	13	,	,	,
cord-350019-4nlbu54e	445	14	there	there	EX
cord-350019-4nlbu54e	445	15	are	be	VBP
cord-350019-4nlbu54e	445	16	some	some	DT
cord-350019-4nlbu54e	445	17	shortcomings	shortcoming	NNS
cord-350019-4nlbu54e	445	18	,	,	,
cord-350019-4nlbu54e	445	19	including	include	VBG
cord-350019-4nlbu54e	445	20	poorly	poorly	RB
cord-350019-4nlbu54e	445	21	annotated	annotate	VBN
cord-350019-4nlbu54e	445	22	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	445	23	transcripts	transcript	NNS
cord-350019-4nlbu54e	445	24	.	.	.
cord-350019-4nlbu54e	446	1	However	however	RB
cord-350019-4nlbu54e	446	2	,	,	,
cord-350019-4nlbu54e	446	3	this	this	DT
cord-350019-4nlbu54e	446	4	will	will	MD
cord-350019-4nlbu54e	446	5	be	be	VB
cord-350019-4nlbu54e	446	6	overcome	overcome	VBN
cord-350019-4nlbu54e	446	7	with	with	IN
cord-350019-4nlbu54e	446	8	direct	direct	JJ
cord-350019-4nlbu54e	446	9	RNA	RNA	NNP
cord-350019-4nlbu54e	446	10	sequencing	sequencing	NN
cord-350019-4nlbu54e	446	11	using	use	VBG
cord-350019-4nlbu54e	446	12	ONT	ONT	NNP
cord-350019-4nlbu54e	446	13	and	and	CC
cord-350019-4nlbu54e	446	14	PacBio	PacBio	NNP
cord-350019-4nlbu54e	446	15	technology	technology	NN
cord-350019-4nlbu54e	446	16	.	.	.
cord-350019-4nlbu54e	447	1	These	these	DT
cord-350019-4nlbu54e	447	2	technologies	technology	NNS
cord-350019-4nlbu54e	447	3	will	will	MD
cord-350019-4nlbu54e	447	4	enable	enable	VB
cord-350019-4nlbu54e	447	5	us	-PRON-	PRP
cord-350019-4nlbu54e	447	6	to	to	TO
cord-350019-4nlbu54e	447	7	determine	determine	VB
cord-350019-4nlbu54e	447	8	the	the	DT
cord-350019-4nlbu54e	447	9	exact	exact	JJ
cord-350019-4nlbu54e	447	10	isoforms	isoform	NNS
cord-350019-4nlbu54e	447	11	of	of	IN
cord-350019-4nlbu54e	447	12	transcripts	transcript	NNS
cord-350019-4nlbu54e	447	13	expressed	express	VBN
cord-350019-4nlbu54e	447	14	in	in	IN
cord-350019-4nlbu54e	447	15	a	a	DT
cord-350019-4nlbu54e	447	16	particular	particular	JJ
cord-350019-4nlbu54e	447	17	cell	cell	NN
cord-350019-4nlbu54e	447	18	and	and	CC
cord-350019-4nlbu54e	447	19	begin	begin	VB
cord-350019-4nlbu54e	447	20	to	to	TO
cord-350019-4nlbu54e	447	21	catalog	catalog	VB
cord-350019-4nlbu54e	447	22	the	the	DT
cord-350019-4nlbu54e	447	23	different	different	JJ
cord-350019-4nlbu54e	447	24	RNA	RNA	NNP
cord-350019-4nlbu54e	447	25	modifications	modification	NNS
cord-350019-4nlbu54e	447	26	that	that	WDT
cord-350019-4nlbu54e	447	27	exist	exist	VBP
cord-350019-4nlbu54e	447	28	basally	basally	RB
cord-350019-4nlbu54e	447	29	and	and	CC
cord-350019-4nlbu54e	447	30	during	during	IN
cord-350019-4nlbu54e	447	31	a	a	DT
cord-350019-4nlbu54e	447	32	biological	biological	JJ
cord-350019-4nlbu54e	447	33	process	process	NN
cord-350019-4nlbu54e	447	34	such	such	JJ
cord-350019-4nlbu54e	447	35	as	as	IN
cord-350019-4nlbu54e	447	36	activation	activation	NN
cord-350019-4nlbu54e	447	37	of	of	IN
cord-350019-4nlbu54e	447	38	inflammation	inflammation	NN
cord-350019-4nlbu54e	447	39	.	.	.
cord-350019-4nlbu54e	448	1	Since	since	IN
cord-350019-4nlbu54e	448	2	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	448	3	are	be	VBP
cord-350019-4nlbu54e	448	4	cell	cell	NN
cord-350019-4nlbu54e	448	5	-	-	HYPH
cord-350019-4nlbu54e	448	6	type	type	NN
cord-350019-4nlbu54e	448	7	specific	specific	NN
cord-350019-4nlbu54e	448	8	in	in	IN
cord-350019-4nlbu54e	448	9	their	-PRON-	PRP$
cord-350019-4nlbu54e	448	10	expression	expression	NN
cord-350019-4nlbu54e	448	11	patterns	pattern	NNS
cord-350019-4nlbu54e	448	12	continued	continue	VBD
cord-350019-4nlbu54e	448	13	development	development	NN
cord-350019-4nlbu54e	448	14	of	of	IN
cord-350019-4nlbu54e	448	15	single	single	JJ
cord-350019-4nlbu54e	448	16	-	-	HYPH
cord-350019-4nlbu54e	448	17	cell	cell	NN
cord-350019-4nlbu54e	448	18	sequencing	sequencing	NN
cord-350019-4nlbu54e	448	19	technologies	technology	NNS
cord-350019-4nlbu54e	448	20	will	will	MD
cord-350019-4nlbu54e	448	21	provide	provide	VB
cord-350019-4nlbu54e	448	22	a	a	DT
cord-350019-4nlbu54e	448	23	complete	complete	JJ
cord-350019-4nlbu54e	448	24	catalog	catalog	NN
cord-350019-4nlbu54e	448	25	of	of	IN
cord-350019-4nlbu54e	448	26	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	448	27	in	in	IN
cord-350019-4nlbu54e	448	28	the	the	DT
cord-350019-4nlbu54e	448	29	genome	genome	NN
cord-350019-4nlbu54e	448	30	.	.	.
cord-350019-4nlbu54e	449	1	As	as	IN
cord-350019-4nlbu54e	449	2	the	the	DT
cord-350019-4nlbu54e	449	3	list	list	NN
cord-350019-4nlbu54e	449	4	of	of	IN
cord-350019-4nlbu54e	449	5	annotated	annotate	VBN
cord-350019-4nlbu54e	449	6	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	449	7	grows	grow	VBZ
cord-350019-4nlbu54e	449	8	,	,	,
cord-350019-4nlbu54e	449	9	characterizing	characterize	VBG
cord-350019-4nlbu54e	449	10	the	the	DT
cord-350019-4nlbu54e	449	11	function	function	NN
cord-350019-4nlbu54e	449	12	of	of	IN
cord-350019-4nlbu54e	449	13	all	all	PDT
cord-350019-4nlbu54e	449	14	these	these	DT
cord-350019-4nlbu54e	449	15	genes	gene	NNS
cord-350019-4nlbu54e	449	16	has	have	VBZ
cord-350019-4nlbu54e	449	17	become	become	VBN
cord-350019-4nlbu54e	449	18	a	a	DT
cord-350019-4nlbu54e	449	19	definite	definite	JJ
cord-350019-4nlbu54e	449	20	bottle	bottle	NN
cord-350019-4nlbu54e	449	21	-	-	HYPH
cord-350019-4nlbu54e	449	22	neck	neck	NN
cord-350019-4nlbu54e	449	23	in	in	IN
cord-350019-4nlbu54e	449	24	the	the	DT
cord-350019-4nlbu54e	449	25	field	field	NN
cord-350019-4nlbu54e	449	26	.	.	.
cord-350019-4nlbu54e	450	1	However	however	RB
cord-350019-4nlbu54e	450	2	,	,	,
cord-350019-4nlbu54e	450	3	highthroughput	highthroughput	NN
cord-350019-4nlbu54e	450	4	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	450	5	screening	screening	NN
cord-350019-4nlbu54e	450	6	provides	provide	VBZ
cord-350019-4nlbu54e	450	7	an	an	DT
cord-350019-4nlbu54e	450	8	approach	approach	NN
cord-350019-4nlbu54e	450	9	to	to	TO
cord-350019-4nlbu54e	450	10	quickly	quickly	RB
cord-350019-4nlbu54e	450	11	identify	identify	VB
cord-350019-4nlbu54e	450	12	functional	functional	JJ
cord-350019-4nlbu54e	450	13	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	450	14	in	in	IN
cord-350019-4nlbu54e	450	15	a	a	DT
cord-350019-4nlbu54e	450	16	particular	particular	JJ
cord-350019-4nlbu54e	450	17	biological	biological	JJ
cord-350019-4nlbu54e	450	18	system	system	NN
cord-350019-4nlbu54e	450	19	.	.	.
cord-350019-4nlbu54e	451	1	Utilizing	utilize	VBG
cord-350019-4nlbu54e	451	2	all	all	PDT
cord-350019-4nlbu54e	451	3	the	the	DT
cord-350019-4nlbu54e	451	4	tools	tool	NNS
cord-350019-4nlbu54e	451	5	outlined	outline	VBN
cord-350019-4nlbu54e	451	6	here	here	RB
cord-350019-4nlbu54e	451	7	should	should	MD
cord-350019-4nlbu54e	451	8	enable	enable	VB
cord-350019-4nlbu54e	451	9	researchers	researcher	NNS
cord-350019-4nlbu54e	451	10	to	to	TO
cord-350019-4nlbu54e	451	11	develop	develop	VB
cord-350019-4nlbu54e	451	12	this	this	DT
cord-350019-4nlbu54e	451	13	field	field	NN
cord-350019-4nlbu54e	451	14	rapidly	rapidly	RB
cord-350019-4nlbu54e	451	15	.	.	.
cord-350019-4nlbu54e	452	1	For	for	IN
cord-350019-4nlbu54e	452	2	our	-PRON-	PRP$
cord-350019-4nlbu54e	452	3	research	research	NN
cord-350019-4nlbu54e	452	4	focus	focus	NN
cord-350019-4nlbu54e	452	5	,	,	,
cord-350019-4nlbu54e	452	6	gaining	gain	VBG
cord-350019-4nlbu54e	452	7	a	a	DT
cord-350019-4nlbu54e	452	8	better	well	JJR
cord-350019-4nlbu54e	452	9	understanding	understanding	NN
cord-350019-4nlbu54e	452	10	of	of	IN
cord-350019-4nlbu54e	452	11	the	the	DT
cord-350019-4nlbu54e	452	12	role	role	NN
cord-350019-4nlbu54e	452	13	of	of	IN
cord-350019-4nlbu54e	452	14	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	452	15	in	in	IN
cord-350019-4nlbu54e	452	16	regulating	regulate	VBG
cord-350019-4nlbu54e	452	17	immune	immune	JJ
cord-350019-4nlbu54e	452	18	responses	response	NNS
cord-350019-4nlbu54e	452	19	will	will	MD
cord-350019-4nlbu54e	452	20	provide	provide	VB
cord-350019-4nlbu54e	452	21	novel	novel	JJ
cord-350019-4nlbu54e	452	22	insights	insight	NNS
cord-350019-4nlbu54e	452	23	into	into	IN
cord-350019-4nlbu54e	452	24	the	the	DT
cord-350019-4nlbu54e	452	25	molecular	molecular	JJ
cord-350019-4nlbu54e	452	26	mechanisms	mechanism	NNS
cord-350019-4nlbu54e	452	27	governing	govern	VBG
cord-350019-4nlbu54e	452	28	inflammation	inflammation	NN
cord-350019-4nlbu54e	452	29	.	.	.
cord-350019-4nlbu54e	453	1	This	this	DT
cord-350019-4nlbu54e	453	2	data	datum	NNS
cord-350019-4nlbu54e	453	3	will	will	MD
cord-350019-4nlbu54e	453	4	be	be	VB
cord-350019-4nlbu54e	453	5	critical	critical	JJ
cord-350019-4nlbu54e	453	6	for	for	IN
cord-350019-4nlbu54e	453	7	identifying	identify	VBG
cord-350019-4nlbu54e	453	8	new	new	JJ
cord-350019-4nlbu54e	453	9	avenues	avenue	NNS
cord-350019-4nlbu54e	453	10	for	for	IN
cord-350019-4nlbu54e	453	11	therapeutic	therapeutic	JJ
cord-350019-4nlbu54e	453	12	intervention	intervention	NN
cord-350019-4nlbu54e	453	13	for	for	IN
cord-350019-4nlbu54e	453	14	infectious	infectious	JJ
cord-350019-4nlbu54e	453	15	and	and	CC
cord-350019-4nlbu54e	453	16	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	453	17	disease	disease	NN
cord-350019-4nlbu54e	453	18	.	.	.
cord-350019-4nlbu54e	454	1	The	the	DT
cord-350019-4nlbu54e	454	2	Transparency	Transparency	NNP
cord-350019-4nlbu54e	454	3	document	document	NN
cord-350019-4nlbu54e	454	4	associated	associate	VBN
cord-350019-4nlbu54e	454	5	with	with	IN
cord-350019-4nlbu54e	454	6	this	this	DT
cord-350019-4nlbu54e	454	7	article	article	NN
cord-350019-4nlbu54e	454	8	can	can	MD
cord-350019-4nlbu54e	454	9	be	be	VB
cord-350019-4nlbu54e	454	10	found	find	VBN
cord-350019-4nlbu54e	454	11	,	,	,
cord-350019-4nlbu54e	454	12	in	in	IN
cord-350019-4nlbu54e	454	13	the	the	DT
cord-350019-4nlbu54e	454	14	online	online	JJ
cord-350019-4nlbu54e	454	15	version	version	NN
cord-350019-4nlbu54e	454	16	.	.	.
cord-350019-4nlbu54e	455	1	Pervasive	pervasive	JJ
cord-350019-4nlbu54e	455	2	transcription	transcription	NN
cord-350019-4nlbu54e	455	3	of	of	IN
cord-350019-4nlbu54e	455	4	the	the	DT
cord-350019-4nlbu54e	455	5	human	human	JJ
cord-350019-4nlbu54e	455	6	genome	genome	NN
cord-350019-4nlbu54e	455	7	produces	produce	VBZ
cord-350019-4nlbu54e	455	8	thousands	thousand	NNS
cord-350019-4nlbu54e	455	9	of	of	IN
cord-350019-4nlbu54e	455	10	previously	previously	RB
cord-350019-4nlbu54e	455	11	unidentified	unidentified	JJ
cord-350019-4nlbu54e	455	12	long	long	RB
cord-350019-4nlbu54e	455	13	intergenic	intergenic	JJ
cord-350019-4nlbu54e	455	14	noncoding	noncoding	JJ
cord-350019-4nlbu54e	455	15	RNAs	rna	NNS
cord-350019-4nlbu54e	456	1	The	the	DT
cord-350019-4nlbu54e	456	2	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	456	3	landscape	landscape	NN
cord-350019-4nlbu54e	456	4	of	of	IN
cord-350019-4nlbu54e	456	5	the	the	DT
cord-350019-4nlbu54e	456	6	mammalian	mammalian	JJ
cord-350019-4nlbu54e	456	7	genome	genome	NN
cord-350019-4nlbu54e	457	1	A	a	DT
cord-350019-4nlbu54e	457	2	promoter	promoter	NN
cord-350019-4nlbu54e	457	3	-	-	HYPH
cord-350019-4nlbu54e	457	4	level	level	NN
cord-350019-4nlbu54e	457	5	mammalian	mammalian	JJ
cord-350019-4nlbu54e	457	6	expression	expression	NN
cord-350019-4nlbu54e	457	7	atlas	atlas	NNP
cord-350019-4nlbu54e	458	1	The	the	DT
cord-350019-4nlbu54e	458	2	GENCODE	GENCODE	NNP
cord-350019-4nlbu54e	458	3	v7	v7	NNP
cord-350019-4nlbu54e	458	4	catalog	catalog	NN
cord-350019-4nlbu54e	458	5	of	of	IN
cord-350019-4nlbu54e	458	6	human	human	JJ
cord-350019-4nlbu54e	458	7	long	long	JJ
cord-350019-4nlbu54e	458	8	noncoding	noncoding	JJ
cord-350019-4nlbu54e	458	9	RNAs	rna	NNS
cord-350019-4nlbu54e	458	10	:	:	:
cord-350019-4nlbu54e	458	11	analysis	analysis	NN
cord-350019-4nlbu54e	458	12	of	of	IN
cord-350019-4nlbu54e	458	13	their	-PRON-	PRP$
cord-350019-4nlbu54e	458	14	gene	gene	NN
cord-350019-4nlbu54e	458	15	structure	structure	NN
cord-350019-4nlbu54e	458	16	,	,	,
cord-350019-4nlbu54e	458	17	evolution	evolution	NN
cord-350019-4nlbu54e	458	18	,	,	,
cord-350019-4nlbu54e	458	19	and	and	CC
cord-350019-4nlbu54e	458	20	expression	expression	NN
cord-350019-4nlbu54e	458	21	Long	long	JJ
cord-350019-4nlbu54e	458	22	non	non	JJ
cord-350019-4nlbu54e	458	23	-	-	JJ
cord-350019-4nlbu54e	458	24	coding	code	VBG
cord-350019-4nlbu54e	458	25	rnas	rnas	NN
cord-350019-4nlbu54e	458	26	and	and	CC
cord-350019-4nlbu54e	458	27	control	control	NN
cord-350019-4nlbu54e	458	28	of	of	IN
cord-350019-4nlbu54e	458	29	gene	gene	NN
cord-350019-4nlbu54e	458	30	expression	expression	NN
cord-350019-4nlbu54e	458	31	in	in	IN
cord-350019-4nlbu54e	458	32	the	the	DT
cord-350019-4nlbu54e	458	33	immune	immune	JJ
cord-350019-4nlbu54e	458	34	system	system	NN
cord-350019-4nlbu54e	458	35	Bases	Bases	NNPS
cord-350019-4nlbu54e	458	36	of	of	IN
cord-350019-4nlbu54e	458	37	antisense	antisense	NN
cord-350019-4nlbu54e	458	38	lncRNA	lncrna	NN
cord-350019-4nlbu54e	458	39	-	-	HYPH
cord-350019-4nlbu54e	458	40	associated	associate	VBN
cord-350019-4nlbu54e	458	41	regulation	regulation	NN
cord-350019-4nlbu54e	458	42	of	of	IN
cord-350019-4nlbu54e	458	43	gene	gene	NN
cord-350019-4nlbu54e	458	44	expression	expression	NN
cord-350019-4nlbu54e	458	45	in	in	IN
cord-350019-4nlbu54e	458	46	fission	fission	NN
cord-350019-4nlbu54e	458	47	yeast	yeast	NN
cord-350019-4nlbu54e	458	48	Detection	detection	NN
cord-350019-4nlbu54e	458	49	of	of	IN
cord-350019-4nlbu54e	458	50	bidirectional	bidirectional	JJ
cord-350019-4nlbu54e	458	51	promoter	promoter	NN
cord-350019-4nlbu54e	458	52	-	-	HYPH
cord-350019-4nlbu54e	458	53	derived	derive	VBN
cord-350019-4nlbu54e	458	54	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	458	55	from	from	IN
cord-350019-4nlbu54e	458	56	small	small	JJ
cord-350019-4nlbu54e	458	57	-	-	HYPH
cord-350019-4nlbu54e	458	58	scale	scale	NN
cord-350019-4nlbu54e	458	59	samples	sample	NNS
cord-350019-4nlbu54e	458	60	using	use	VBG
cord-350019-4nlbu54e	458	61	pre	pre	JJ
cord-350019-4nlbu54e	458	62	-	-	JJ
cord-350019-4nlbu54e	458	63	amplification	amplification	NN
cord-350019-4nlbu54e	458	64	-	-	HYPH
cord-350019-4nlbu54e	458	65	free	free	JJ
cord-350019-4nlbu54e	458	66	directional	directional	JJ
cord-350019-4nlbu54e	458	67	RNA	rna	NN
cord-350019-4nlbu54e	458	68	-	-	HYPH
cord-350019-4nlbu54e	458	69	seq	seq	NN
cord-350019-4nlbu54e	458	70	method	method	NN
cord-350019-4nlbu54e	458	71	Enhancer	Enhancer	NNP
cord-350019-4nlbu54e	458	72	RNAs	rna	NNS
cord-350019-4nlbu54e	458	73	(	(	-LRB-
cord-350019-4nlbu54e	458	74	eRNAs	ernas	CD
cord-350019-4nlbu54e	458	75	)	)	-RRB-
cord-350019-4nlbu54e	458	76	:	:	:
cord-350019-4nlbu54e	458	77	new	new	JJ
cord-350019-4nlbu54e	458	78	insights	insight	NNS
cord-350019-4nlbu54e	458	79	into	into	IN
cord-350019-4nlbu54e	458	80	gene	gene	NN
cord-350019-4nlbu54e	458	81	transcription	transcription	NN
cord-350019-4nlbu54e	458	82	and	and	CC
cord-350019-4nlbu54e	458	83	disease	disease	NN
cord-350019-4nlbu54e	458	84	treatment	treatment	NN
cord-350019-4nlbu54e	458	85	XLincRNAs	XLincRNAs	NNP
cord-350019-4nlbu54e	458	86	:	:	:
cord-350019-4nlbu54e	458	87	genomics	genomic	NNS
cord-350019-4nlbu54e	458	88	,	,	,
cord-350019-4nlbu54e	458	89	evolution	evolution	NN
cord-350019-4nlbu54e	458	90	,	,	,
cord-350019-4nlbu54e	458	91	and	and	CC
cord-350019-4nlbu54e	458	92	mechanisms	mechanism	NNS
cord-350019-4nlbu54e	459	1	History	history	NN
cord-350019-4nlbu54e	459	2	,	,	,
cord-350019-4nlbu54e	459	3	discovery	discovery	NN
cord-350019-4nlbu54e	459	4	,	,	,
cord-350019-4nlbu54e	459	5	and	and	CC
cord-350019-4nlbu54e	459	6	classification	classification	NN
cord-350019-4nlbu54e	459	7	of	of	IN
cord-350019-4nlbu54e	459	8	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	459	9	Soybean	Soybean	NNP
cord-350019-4nlbu54e	459	10	ENOD40	ENOD40	NNP
cord-350019-4nlbu54e	459	11	encodes	encode	VBZ
cord-350019-4nlbu54e	459	12	two	two	CD
cord-350019-4nlbu54e	459	13	peptides	peptide	NNS
cord-350019-4nlbu54e	459	14	that	that	WDT
cord-350019-4nlbu54e	459	15	bind	bind	VBP
cord-350019-4nlbu54e	459	16	to	to	IN
cord-350019-4nlbu54e	459	17	sucrose	sucrose	NN
cord-350019-4nlbu54e	459	18	synthase	synthase	NN
cord-350019-4nlbu54e	459	19	A	a	NN
cord-350019-4nlbu54e	459	20	micropeptide	micropeptide	NN
cord-350019-4nlbu54e	459	21	encoded	encode	VBN
cord-350019-4nlbu54e	459	22	by	by	IN
cord-350019-4nlbu54e	459	23	a	a	DT
cord-350019-4nlbu54e	459	24	putative	putative	JJ
cord-350019-4nlbu54e	459	25	long	long	JJ
cord-350019-4nlbu54e	459	26	noncoding	noncoding	JJ
cord-350019-4nlbu54e	459	27	RNA	RNA	NNP
cord-350019-4nlbu54e	459	28	regulates	regulate	VBZ
cord-350019-4nlbu54e	459	29	muscle	muscle	NN
cord-350019-4nlbu54e	459	30	performance	performance	NN
cord-350019-4nlbu54e	459	31	A	a	DT
cord-350019-4nlbu54e	459	32	peptide	peptide	NN
cord-350019-4nlbu54e	459	33	encoded	encode	VBN
cord-350019-4nlbu54e	459	34	by	by	IN
cord-350019-4nlbu54e	459	35	a	a	DT
cord-350019-4nlbu54e	459	36	transcript	transcript	NN
cord-350019-4nlbu54e	459	37	annotated	annotate	VBN
cord-350019-4nlbu54e	459	38	as	as	IN
cord-350019-4nlbu54e	459	39	long	long	JJ
cord-350019-4nlbu54e	459	40	noncoding	noncoding	NNP
cord-350019-4nlbu54e	459	41	RNA	RNA	NNP
cord-350019-4nlbu54e	459	42	enhances	enhance	VBZ
cord-350019-4nlbu54e	459	43	SERCA	SERCA	NNP
cord-350019-4nlbu54e	459	44	activity	activity	NN
cord-350019-4nlbu54e	459	45	in	in	IN
cord-350019-4nlbu54e	459	46	muscle	muscle	NN
cord-350019-4nlbu54e	459	47	MTORC1	MTORC1	NNS
cord-350019-4nlbu54e	459	48	and	and	CC
cord-350019-4nlbu54e	459	49	muscle	muscle	NN
cord-350019-4nlbu54e	459	50	regeneration	regeneration	NN
cord-350019-4nlbu54e	459	51	are	be	VBP
cord-350019-4nlbu54e	459	52	regulated	regulate	VBN
cord-350019-4nlbu54e	459	53	by	by	IN
cord-350019-4nlbu54e	459	54	the	the	DT
cord-350019-4nlbu54e	459	55	LINC00961-encoded	linc00961-encoded	JJ
cord-350019-4nlbu54e	459	56	SPAR	SPAR	NNP
cord-350019-4nlbu54e	459	57	polypeptide	polypeptide	NN
cord-350019-4nlbu54e	460	1	Circ	Circ	NNP
cord-350019-4nlbu54e	460	2	-	-	HYPH
cord-350019-4nlbu54e	460	3	ZNF609	ZNF609	NNP
cord-350019-4nlbu54e	460	4	is	be	VBZ
cord-350019-4nlbu54e	460	5	a	a	DT
cord-350019-4nlbu54e	460	6	circular	circular	JJ
cord-350019-4nlbu54e	460	7	RNA	rna	NN
cord-350019-4nlbu54e	460	8	that	that	WDT
cord-350019-4nlbu54e	460	9	can	can	MD
cord-350019-4nlbu54e	460	10	be	be	VB
cord-350019-4nlbu54e	460	11	translated	translate	VBN
cord-350019-4nlbu54e	460	12	and	and	CC
cord-350019-4nlbu54e	460	13	functions	function	NNS
cord-350019-4nlbu54e	460	14	in	in	IN
cord-350019-4nlbu54e	460	15	myogenesis	myogenesis	NN
cord-350019-4nlbu54e	460	16	Viral	viral	JJ
cord-350019-4nlbu54e	460	17	infection	infection	NN
cord-350019-4nlbu54e	460	18	identifies	identify	VBZ
cord-350019-4nlbu54e	460	19	micropeptides	micropeptides	NNP
cord-350019-4nlbu54e	460	20	differentially	differentially	RB
cord-350019-4nlbu54e	460	21	regulated	regulate	VBN
cord-350019-4nlbu54e	460	22	in	in	IN
cord-350019-4nlbu54e	460	23	smORF	smorf	RB
cord-350019-4nlbu54e	460	24	-	-	HYPH
cord-350019-4nlbu54e	460	25	containing	contain	VBG
cord-350019-4nlbu54e	460	26	lncrnas	lncrnas	NNP
cord-350019-4nlbu54e	460	27	Control	Control	NNP
cord-350019-4nlbu54e	460	28	of	of	IN
cord-350019-4nlbu54e	460	29	adaptive	adaptive	JJ
cord-350019-4nlbu54e	460	30	immunity	immunity	NN
cord-350019-4nlbu54e	460	31	by	by	IN
cord-350019-4nlbu54e	460	32	the	the	DT
cord-350019-4nlbu54e	460	33	innate	innate	JJ
cord-350019-4nlbu54e	460	34	immune	immune	JJ
cord-350019-4nlbu54e	460	35	system	system	NN
cord-350019-4nlbu54e	461	1	Innate	innate	JJ
cord-350019-4nlbu54e	461	2	immune	immune	JJ
cord-350019-4nlbu54e	461	3	recognition	recognition	NN
cord-350019-4nlbu54e	461	4	:	:	:
cord-350019-4nlbu54e	461	5	mechanisms	mechanism	NNS
cord-350019-4nlbu54e	461	6	and	and	CC
cord-350019-4nlbu54e	461	7	pathways	pathway	NNS
cord-350019-4nlbu54e	461	8	Toll	Toll	NNP
cord-350019-4nlbu54e	461	9	-	-	HYPH
cord-350019-4nlbu54e	461	10	like	like	JJ
cord-350019-4nlbu54e	461	11	receptor	receptor	NN
cord-350019-4nlbu54e	461	12	stimulation	stimulation	NN
cord-350019-4nlbu54e	461	13	in	in	IN
cord-350019-4nlbu54e	461	14	cancer	cancer	NN
cord-350019-4nlbu54e	461	15	:	:	:
cord-350019-4nlbu54e	461	16	a	a	DT
cord-350019-4nlbu54e	461	17	proand	proand	NN
cord-350019-4nlbu54e	461	18	anti	anti	JJ
cord-350019-4nlbu54e	461	19	-	-	JJ
cord-350019-4nlbu54e	461	20	tumor	tumor	JJ
cord-350019-4nlbu54e	461	21	double	double	RB
cord-350019-4nlbu54e	461	22	-	-	HYPH
cord-350019-4nlbu54e	461	23	edged	edged	JJ
cord-350019-4nlbu54e	461	24	sword	sword	NN
cord-350019-4nlbu54e	461	25	Long	Long	NNP
cord-350019-4nlbu54e	461	26	noncoding	noncoding	NNP
cord-350019-4nlbu54e	461	27	RNA	RNA	NNP
cord-350019-4nlbu54e	461	28	:	:	:
cord-350019-4nlbu54e	462	1	novel	novel	JJ
cord-350019-4nlbu54e	462	2	links	link	NNS
cord-350019-4nlbu54e	462	3	between	between	IN
cord-350019-4nlbu54e	462	4	gene	gene	NN
cord-350019-4nlbu54e	462	5	expression	expression	NN
cord-350019-4nlbu54e	462	6	and	and	CC
cord-350019-4nlbu54e	462	7	innate	innate	JJ
cord-350019-4nlbu54e	462	8	immunity	immunity	NN
cord-350019-4nlbu54e	462	9	Role	role	NN
cord-350019-4nlbu54e	462	10	of	of	IN
cord-350019-4nlbu54e	462	11	low	low	JJ
cord-350019-4nlbu54e	462	12	-	-	HYPH
cord-350019-4nlbu54e	462	13	grade	grade	NN
cord-350019-4nlbu54e	462	14	inflammation	inflammation	NN
cord-350019-4nlbu54e	462	15	in	in	IN
cord-350019-4nlbu54e	462	16	osteoarthritis	osteoarthritis	NN
cord-350019-4nlbu54e	462	17	Role	role	NN
cord-350019-4nlbu54e	462	18	of	of	IN
cord-350019-4nlbu54e	462	19	toll	toll	NN
cord-350019-4nlbu54e	462	20	-	-	HYPH
cord-350019-4nlbu54e	462	21	like	like	JJ
cord-350019-4nlbu54e	462	22	receptors	receptor	NNS
cord-350019-4nlbu54e	462	23	in	in	IN
cord-350019-4nlbu54e	462	24	multiple	multiple	JJ
cord-350019-4nlbu54e	462	25	sclerosis	sclerosis	NN
cord-350019-4nlbu54e	462	26	Interconnection	interconnection	NN
cord-350019-4nlbu54e	462	27	between	between	IN
cord-350019-4nlbu54e	462	28	DNA	dna	NN
cord-350019-4nlbu54e	462	29	damage	damage	NN
cord-350019-4nlbu54e	462	30	,	,	,
cord-350019-4nlbu54e	462	31	senescence	senescence	NN
cord-350019-4nlbu54e	462	32	,	,	,
cord-350019-4nlbu54e	462	33	inflammation	inflammation	NN
cord-350019-4nlbu54e	462	34	,	,	,
cord-350019-4nlbu54e	462	35	and	and	CC
cord-350019-4nlbu54e	462	36	cancer	cancer	NN
cord-350019-4nlbu54e	462	37	Long	Long	NNP
cord-350019-4nlbu54e	462	38	noncoding	noncoding	NNP
cord-350019-4nlbu54e	462	39	RNA	RNA	NNP
cord-350019-4nlbu54e	462	40	in	in	IN
cord-350019-4nlbu54e	462	41	hematopoiesis	hematopoiesis	NN
cord-350019-4nlbu54e	462	42	and	and	CC
cord-350019-4nlbu54e	462	43	immunity	immunity	NN
cord-350019-4nlbu54e	462	44	Long	long	JJ
cord-350019-4nlbu54e	462	45	noncoding	noncoding	JJ
cord-350019-4nlbu54e	462	46	RNAs	rna	NNS
cord-350019-4nlbu54e	462	47	:	:	:
cord-350019-4nlbu54e	462	48	cellular	cellular	JJ
cord-350019-4nlbu54e	462	49	address	address	NN
cord-350019-4nlbu54e	462	50	codes	code	NNS
cord-350019-4nlbu54e	462	51	in	in	IN
cord-350019-4nlbu54e	462	52	development	development	NN
cord-350019-4nlbu54e	462	53	and	and	CC
cord-350019-4nlbu54e	462	54	disease	disease	NN
cord-350019-4nlbu54e	463	1	Long	long	JJ
cord-350019-4nlbu54e	463	2	non	non	JJ
cord-350019-4nlbu54e	463	3	-	-	JJ
cord-350019-4nlbu54e	463	4	coding	coding	JJ
cord-350019-4nlbu54e	463	5	RNAs	rna	NNS
cord-350019-4nlbu54e	463	6	:	:	:
cord-350019-4nlbu54e	463	7	new	new	JJ
cord-350019-4nlbu54e	463	8	players	player	NNS
cord-350019-4nlbu54e	463	9	in	in	IN
cord-350019-4nlbu54e	463	10	cell	cell	NN
cord-350019-4nlbu54e	463	11	differentiation	differentiation	NN
cord-350019-4nlbu54e	463	12	and	and	CC
cord-350019-4nlbu54e	463	13	development	development	NN
cord-350019-4nlbu54e	463	14	Long	Long	NNP
cord-350019-4nlbu54e	463	15	noncoding	noncoding	NNP
cord-350019-4nlbu54e	463	16	RNA	RNA	NNP
cord-350019-4nlbu54e	463	17	transcriptome	transcriptome	NN
cord-350019-4nlbu54e	463	18	of	of	IN
cord-350019-4nlbu54e	463	19	plants	plant	NNS
cord-350019-4nlbu54e	464	1	Long	long	JJ
cord-350019-4nlbu54e	464	2	noncoding	noncoding	JJ
cord-350019-4nlbu54e	464	3	RNAs	rna	NNS
cord-350019-4nlbu54e	464	4	:	:	:
cord-350019-4nlbu54e	464	5	regulation	regulation	NN
cord-350019-4nlbu54e	464	6	,	,	,
cord-350019-4nlbu54e	464	7	function	function	NN
cord-350019-4nlbu54e	464	8	and	and	CC
cord-350019-4nlbu54e	464	9	cancer	cancer	NN
cord-350019-4nlbu54e	464	10	Emerging	Emerging	NNP
cord-350019-4nlbu54e	464	11	role	role	NN
cord-350019-4nlbu54e	464	12	of	of	IN
cord-350019-4nlbu54e	464	13	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	464	14	in	in	IN
cord-350019-4nlbu54e	464	15	cancer	cancer	NN
cord-350019-4nlbu54e	464	16	:	:	:
cord-350019-4nlbu54e	464	17	a	a	DT
cord-350019-4nlbu54e	464	18	potential	potential	JJ
cord-350019-4nlbu54e	464	19	avenue	avenue	NN
cord-350019-4nlbu54e	464	20	in	in	IN
cord-350019-4nlbu54e	464	21	molecular	molecular	JJ
cord-350019-4nlbu54e	464	22	medicine	medicine	NN
cord-350019-4nlbu54e	464	23	Noncoding	Noncoding	NNP
cord-350019-4nlbu54e	464	24	RNA	RNA	NNP
cord-350019-4nlbu54e	464	25	:	:	:
cord-350019-4nlbu54e	464	26	RNA	RNA	NNP
cord-350019-4nlbu54e	464	27	regulatory	regulatory	JJ
cord-350019-4nlbu54e	464	28	networks	network	NNS
cord-350019-4nlbu54e	464	29	in	in	IN
cord-350019-4nlbu54e	464	30	cancer	cancer	NN
cord-350019-4nlbu54e	465	1	The	the	DT
cord-350019-4nlbu54e	465	2	impact	impact	NN
cord-350019-4nlbu54e	465	3	of	of	IN
cord-350019-4nlbu54e	465	4	lncRNA	lncrna	NN
cord-350019-4nlbu54e	465	5	dysregulation	dysregulation	NN
cord-350019-4nlbu54e	465	6	on	on	IN
cord-350019-4nlbu54e	465	7	clinicopathology	clinicopathology	NN
cord-350019-4nlbu54e	465	8	and	and	CC
cord-350019-4nlbu54e	465	9	survival	survival	NN
cord-350019-4nlbu54e	465	10	of	of	IN
cord-350019-4nlbu54e	465	11	breast	breast	NN
cord-350019-4nlbu54e	465	12	cancer	cancer	NN
cord-350019-4nlbu54e	465	13	:	:	:
cord-350019-4nlbu54e	465	14	a	a	DT
cord-350019-4nlbu54e	465	15	systematic	systematic	JJ
cord-350019-4nlbu54e	465	16	review	review	NN
cord-350019-4nlbu54e	465	17	and	and	CC
cord-350019-4nlbu54e	466	1	meta	meta	NNP
cord-350019-4nlbu54e	466	2	-	-	HYPH
cord-350019-4nlbu54e	466	3	analysis	analysis	NN
cord-350019-4nlbu54e	466	4	Prostate	Prostate	NNP
cord-350019-4nlbu54e	466	5	cancer	cancer	NN
cord-350019-4nlbu54e	466	6	-	-	HYPH
cord-350019-4nlbu54e	466	7	associated	associate	VBN
cord-350019-4nlbu54e	466	8	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	467	1	The	the	DT
cord-350019-4nlbu54e	467	2	critical	critical	JJ
cord-350019-4nlbu54e	467	3	role	role	NN
cord-350019-4nlbu54e	467	4	of	of	IN
cord-350019-4nlbu54e	467	5	toll	toll	NN
cord-350019-4nlbu54e	467	6	-	-	HYPH
cord-350019-4nlbu54e	467	7	like	like	JJ
cord-350019-4nlbu54e	467	8	receptors	receptor	NNS
cord-350019-4nlbu54e	467	9	-from	-from	IN
cord-350019-4nlbu54e	467	10	microbial	microbial	JJ
cord-350019-4nlbu54e	467	11	recognition	recognition	NN
cord-350019-4nlbu54e	467	12	to	to	IN
cord-350019-4nlbu54e	467	13	autoimmunity	autoimmunity	NN
cord-350019-4nlbu54e	467	14	:	:	:
cord-350019-4nlbu54e	467	15	a	a	DT
cord-350019-4nlbu54e	467	16	comprehensive	comprehensive	JJ
cord-350019-4nlbu54e	467	17	review	review	NN
cord-350019-4nlbu54e	468	1	Innate	innate	JJ
cord-350019-4nlbu54e	468	2	immune	immune	JJ
cord-350019-4nlbu54e	468	3	pattern	pattern	NN
cord-350019-4nlbu54e	468	4	recognition	recognition	NN
cord-350019-4nlbu54e	468	5	:	:	:
cord-350019-4nlbu54e	468	6	a	a	DT
cord-350019-4nlbu54e	468	7	cell	cell	NN
cord-350019-4nlbu54e	468	8	biological	biological	JJ
cord-350019-4nlbu54e	468	9	perspective	perspective	NN
cord-350019-4nlbu54e	468	10	Transcriptional	Transcriptional	NNP
cord-350019-4nlbu54e	468	11	control	control	NN
cord-350019-4nlbu54e	468	12	of	of	IN
cord-350019-4nlbu54e	468	13	the	the	DT
cord-350019-4nlbu54e	468	14	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	468	15	response	response	NN
cord-350019-4nlbu54e	469	1	Transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	469	2	regulation	regulation	NN
cord-350019-4nlbu54e	469	3	in	in	IN
cord-350019-4nlbu54e	469	4	the	the	DT
cord-350019-4nlbu54e	469	5	innate	innate	JJ
cord-350019-4nlbu54e	469	6	immune	immune	JJ
cord-350019-4nlbu54e	469	7	system	system	NN
cord-350019-4nlbu54e	469	8	Toll	toll	NN
cord-350019-4nlbu54e	469	9	-	-	HYPH
cord-350019-4nlbu54e	469	10	like	like	JJ
cord-350019-4nlbu54e	469	11	receptors	receptor	NNS
cord-350019-4nlbu54e	469	12	in	in	IN
cord-350019-4nlbu54e	469	13	innate	innate	JJ
cord-350019-4nlbu54e	469	14	immunity	immunity	NN
cord-350019-4nlbu54e	469	15	Toll	toll	NN
cord-350019-4nlbu54e	469	16	-	-	HYPH
cord-350019-4nlbu54e	469	17	like	like	JJ
cord-350019-4nlbu54e	469	18	receptors	receptor	NNS
cord-350019-4nlbu54e	469	19	(	(	-LRB-
cord-350019-4nlbu54e	469	20	TLRs	TLRs	NNP
cord-350019-4nlbu54e	469	21	)	)	-RRB-
cord-350019-4nlbu54e	469	22	and	and	CC
cord-350019-4nlbu54e	469	23	Nod	nod	JJ
cord-350019-4nlbu54e	469	24	-	-	HYPH
cord-350019-4nlbu54e	469	25	like	like	JJ
cord-350019-4nlbu54e	469	26	receptors	receptor	NNS
cord-350019-4nlbu54e	469	27	(	(	-LRB-
cord-350019-4nlbu54e	469	28	NLRs	NLRs	NNP
cord-350019-4nlbu54e	469	29	)	)	-RRB-
cord-350019-4nlbu54e	469	30	in	in	IN
cord-350019-4nlbu54e	469	31	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	469	32	disorders	disorder	NNS
cord-350019-4nlbu54e	469	33	Toll	toll	NN
cord-350019-4nlbu54e	469	34	-	-	HYPH
cord-350019-4nlbu54e	469	35	like	like	JJ
cord-350019-4nlbu54e	469	36	receptors	receptor	NNS
cord-350019-4nlbu54e	469	37	,	,	,
cord-350019-4nlbu54e	469	38	associated	associate	VBN
cord-350019-4nlbu54e	469	39	biological	biological	JJ
cord-350019-4nlbu54e	469	40	roles	role	NNS
cord-350019-4nlbu54e	469	41	,	,	,
cord-350019-4nlbu54e	469	42	and	and	CC
cord-350019-4nlbu54e	469	43	signaling	signal	VBG
cord-350019-4nlbu54e	469	44	networks	network	NNS
cord-350019-4nlbu54e	469	45	in	in	IN
cord-350019-4nlbu54e	469	46	non	non	NNS
cord-350019-4nlbu54e	469	47	-	-	NNS
cord-350019-4nlbu54e	469	48	mammals	mammal	NNS
cord-350019-4nlbu54e	469	49	Toll	toll	NN
cord-350019-4nlbu54e	469	50	-	-	HYPH
cord-350019-4nlbu54e	469	51	like	like	JJ
cord-350019-4nlbu54e	469	52	receptors	receptor	NNS
cord-350019-4nlbu54e	469	53	:	:	:
cord-350019-4nlbu54e	469	54	key	key	JJ
cord-350019-4nlbu54e	469	55	mediators	mediator	NNS
cord-350019-4nlbu54e	469	56	of	of	IN
cord-350019-4nlbu54e	469	57	microbe	microbe	NN
cord-350019-4nlbu54e	469	58	detection	detection	NN
cord-350019-4nlbu54e	470	1	A	a	DT
cord-350019-4nlbu54e	470	2	long	long	JJ
cord-350019-4nlbu54e	470	3	noncoding	noncoding	JJ
cord-350019-4nlbu54e	470	4	RNA	RNA	NNP
cord-350019-4nlbu54e	470	5	mediates	mediate	VBZ
cord-350019-4nlbu54e	470	6	both	both	DT
cord-350019-4nlbu54e	470	7	activation	activation	NN
cord-350019-4nlbu54e	470	8	and	and	CC
cord-350019-4nlbu54e	470	9	repression	repression	NN
cord-350019-4nlbu54e	470	10	of	of	IN
cord-350019-4nlbu54e	470	11	immune	immune	JJ
cord-350019-4nlbu54e	470	12	response	response	NN
cord-350019-4nlbu54e	470	13	genes	gene	NNS
cord-350019-4nlbu54e	470	14	LincRNA	LincRNA	.
cord-350019-4nlbu54e	471	1	-Cox2	-Cox2	:
cord-350019-4nlbu54e	471	2	promotes	promote	VBZ
cord-350019-4nlbu54e	471	3	late	late	JJ
cord-350019-4nlbu54e	471	4	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	471	5	gene	gene	NN
cord-350019-4nlbu54e	471	6	transcription	transcription	NN
cord-350019-4nlbu54e	471	7	in	in	IN
cord-350019-4nlbu54e	471	8	macrophages	macrophage	NNS
cord-350019-4nlbu54e	471	9	through	through	IN
cord-350019-4nlbu54e	471	10	modulating	modulate	VBG
cord-350019-4nlbu54e	471	11	SWI	SWI	NNP
cord-350019-4nlbu54e	471	12	/	/	SYM
cord-350019-4nlbu54e	471	13	SNF	SNF	NNP
cord-350019-4nlbu54e	471	14	-	-	HYPH
cord-350019-4nlbu54e	471	15	mediated	mediate	VBN
cord-350019-4nlbu54e	471	16	chromatin	chromatin	NN
cord-350019-4nlbu54e	471	17	remodeling	remodeling	NN
cord-350019-4nlbu54e	472	1	LincRNA	lincrna	LS
cord-350019-4nlbu54e	472	2	-	-	:
cord-350019-4nlbu54e	472	3	Cox2	Cox2	NNP
cord-350019-4nlbu54e	472	4	modulates	modulate	VBZ
cord-350019-4nlbu54e	472	5	TNF	tnf	NN
cord-350019-4nlbu54e	472	6	-	-	HYPH
cord-350019-4nlbu54e	472	7	α	α	NN
cord-350019-4nlbu54e	472	8	-	-	HYPH
cord-350019-4nlbu54e	472	9	induced	induce	VBN
cord-350019-4nlbu54e	472	10	transcription	transcription	NN
cord-350019-4nlbu54e	472	11	of	of	IN
cord-350019-4nlbu54e	472	12	Il12b	il12b	NN
cord-350019-4nlbu54e	472	13	gene	gene	NN
cord-350019-4nlbu54e	472	14	in	in	IN
cord-350019-4nlbu54e	472	15	intestinal	intestinal	JJ
cord-350019-4nlbu54e	472	16	epithelial	epithelial	JJ
cord-350019-4nlbu54e	472	17	cells	cell	NNS
cord-350019-4nlbu54e	472	18	through	through	IN
cord-350019-4nlbu54e	472	19	regulation	regulation	NN
cord-350019-4nlbu54e	472	20	of	of	IN
cord-350019-4nlbu54e	472	21	Mi-2	Mi-2	NNP
cord-350019-4nlbu54e	472	22	/	/	SYM
cord-350019-4nlbu54e	472	23	NuRD	NuRD	NNP
cord-350019-4nlbu54e	472	24	-	-	HYPH
cord-350019-4nlbu54e	472	25	mediated	mediate	VBN
cord-350019-4nlbu54e	472	26	epigenetic	epigenetic	JJ
cord-350019-4nlbu54e	472	27	histone	histone	NN
cord-350019-4nlbu54e	472	28	modifications	modification	NNS
cord-350019-4nlbu54e	472	29	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	472	30	/	/	SYM
cord-350019-4nlbu54e	472	31	Cas	Cas	NNP
cord-350019-4nlbu54e	472	32	-	-	HYPH
cord-350019-4nlbu54e	472	33	based	base	VBN
cord-350019-4nlbu54e	472	34	screening	screening	NN
cord-350019-4nlbu54e	472	35	of	of	IN
cord-350019-4nlbu54e	472	36	long	long	JJ
cord-350019-4nlbu54e	472	37	non	non	JJ
cord-350019-4nlbu54e	472	38	-	-	JJ
cord-350019-4nlbu54e	472	39	coding	coding	JJ
cord-350019-4nlbu54e	472	40	RNAs	rna	NNS
cord-350019-4nlbu54e	472	41	(	(	-LRB-
cord-350019-4nlbu54e	472	42	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	472	43	)	)	-RRB-
cord-350019-4nlbu54e	472	44	in	in	IN
cord-350019-4nlbu54e	472	45	macrophages	macrophage	NNS
cord-350019-4nlbu54e	472	46	with	with	IN
cord-350019-4nlbu54e	472	47	an	an	DT
cord-350019-4nlbu54e	472	48	NF	nf	NN
cord-350019-4nlbu54e	472	49	-	-	HYPH
cord-350019-4nlbu54e	472	50	κB	κb	CD
cord-350019-4nlbu54e	472	51	reporter	reporter	NN
cord-350019-4nlbu54e	472	52	Genetic	genetic	JJ
cord-350019-4nlbu54e	472	53	models	model	NNS
cord-350019-4nlbu54e	472	54	reveal	reveal	VBP
cord-350019-4nlbu54e	472	55	cis	cis	NNP
cord-350019-4nlbu54e	472	56	and	and	CC
cord-350019-4nlbu54e	472	57	trans	trans	JJ
cord-350019-4nlbu54e	472	58	immune	immune	JJ
cord-350019-4nlbu54e	472	59	-	-	HYPH
cord-350019-4nlbu54e	472	60	regulatory	regulatory	JJ
cord-350019-4nlbu54e	472	61	activities	activity	NNS
cord-350019-4nlbu54e	472	62	for	for	IN
cord-350019-4nlbu54e	472	63	lincRNA	lincrna	RB
cord-350019-4nlbu54e	472	64	-	-	HYPH
cord-350019-4nlbu54e	472	65	Cox2	Cox2	NNP
cord-350019-4nlbu54e	472	66	Long	long	JJ
cord-350019-4nlbu54e	472	67	non	non	JJ
cord-350019-4nlbu54e	472	68	-	-	JJ
cord-350019-4nlbu54e	472	69	coding	coding	JJ
cord-350019-4nlbu54e	472	70	RNAs	rna	NNS
cord-350019-4nlbu54e	472	71	and	and	CC
cord-350019-4nlbu54e	472	72	the	the	DT
cord-350019-4nlbu54e	472	73	innate	innate	JJ
cord-350019-4nlbu54e	472	74	immune	immune	JJ
cord-350019-4nlbu54e	472	75	response	response	NN
cord-350019-4nlbu54e	472	76	Cytokines	Cytokines	NNPS
cord-350019-4nlbu54e	472	77	and	and	CC
cord-350019-4nlbu54e	472	78	long	long	JJ
cord-350019-4nlbu54e	472	79	noncoding	noncoding	JJ
cord-350019-4nlbu54e	472	80	RNAs	rna	NNS
cord-350019-4nlbu54e	473	1	On	on	IN
cord-350019-4nlbu54e	473	2	the	the	DT
cord-350019-4nlbu54e	473	3	classification	classification	NN
cord-350019-4nlbu54e	473	4	of	of	IN
cord-350019-4nlbu54e	473	5	long	long	JJ
cord-350019-4nlbu54e	473	6	non	non	JJ
cord-350019-4nlbu54e	473	7	-	-	JJ
cord-350019-4nlbu54e	473	8	coding	coding	JJ
cord-350019-4nlbu54e	473	9	RNAs	rna	NNS
cord-350019-4nlbu54e	473	10	The	the	DT
cord-350019-4nlbu54e	473	11	landscape	landscape	NN
cord-350019-4nlbu54e	473	12	of	of	IN
cord-350019-4nlbu54e	473	13	long	long	JJ
cord-350019-4nlbu54e	473	14	noncoding	noncoding	JJ
cord-350019-4nlbu54e	473	15	RNA	RNA	NNP
cord-350019-4nlbu54e	473	16	classification	classification	NN
cord-350019-4nlbu54e	473	17	Neighboring	Neighboring	NNP
cord-350019-4nlbu54e	473	18	gene	gene	NN
cord-350019-4nlbu54e	473	19	regulation	regulation	NN
cord-350019-4nlbu54e	473	20	by	by	IN
cord-350019-4nlbu54e	473	21	antisense	antisense	NNP
cord-350019-4nlbu54e	473	22	long	long	JJ
cord-350019-4nlbu54e	473	23	non	non	JJ
cord-350019-4nlbu54e	473	24	-	-	JJ
cord-350019-4nlbu54e	473	25	coding	coding	JJ
cord-350019-4nlbu54e	473	26	RNAs	rna	NNS
cord-350019-4nlbu54e	474	1	Local	local	JJ
cord-350019-4nlbu54e	474	2	regulation	regulation	NN
cord-350019-4nlbu54e	474	3	of	of	IN
cord-350019-4nlbu54e	474	4	gene	gene	NN
cord-350019-4nlbu54e	474	5	expression	expression	NN
cord-350019-4nlbu54e	474	6	by	by	IN
cord-350019-4nlbu54e	474	7	lncRNA	lncrna	NN
cord-350019-4nlbu54e	474	8	promoters	promoter	NNS
cord-350019-4nlbu54e	474	9	,	,	,
cord-350019-4nlbu54e	474	10	transcription	transcription	NN
cord-350019-4nlbu54e	474	11	and	and	CC
cord-350019-4nlbu54e	474	12	splicing	splicing	NN
cord-350019-4nlbu54e	475	1	The	the	DT
cord-350019-4nlbu54e	475	2	long	long	JJ
cord-350019-4nlbu54e	475	3	noncoding	noncoding	JJ
cord-350019-4nlbu54e	475	4	RNA	RNA	NNP
cord-350019-4nlbu54e	475	5	ROCKI	ROCKI	NNP
cord-350019-4nlbu54e	475	6	regulates	regulate	VBZ
cord-350019-4nlbu54e	475	7	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	475	8	gene	gene	NN
cord-350019-4nlbu54e	475	9	expression	expression	NN
cord-350019-4nlbu54e	475	10	Cutting	cut	VBG
cord-350019-4nlbu54e	475	11	edge	edge	NN
cord-350019-4nlbu54e	475	12	:	:	:
cord-350019-4nlbu54e	475	13	a	a	DT
cord-350019-4nlbu54e	475	14	natural	natural	JJ
cord-350019-4nlbu54e	475	15	antisense	antisense	NN
cord-350019-4nlbu54e	475	16	transcript	transcript	NN
cord-350019-4nlbu54e	475	17	,	,	,
cord-350019-4nlbu54e	475	18	AS	AS	NNP
cord-350019-4nlbu54e	475	19	-	-	HYPH
cord-350019-4nlbu54e	475	20	IL1α	IL1α	NNP
cord-350019-4nlbu54e	475	21	,	,	,
cord-350019-4nlbu54e	475	22	controls	control	VBZ
cord-350019-4nlbu54e	475	23	inducible	inducible	JJ
cord-350019-4nlbu54e	475	24	transcription	transcription	NN
cord-350019-4nlbu54e	475	25	of	of	IN
cord-350019-4nlbu54e	475	26	the	the	DT
cord-350019-4nlbu54e	475	27	proinflammatory	proinflammatory	JJ
cord-350019-4nlbu54e	475	28	cytokine	cytokine	NN
cord-350019-4nlbu54e	476	1	IL-1α	IL-1α	NNP
cord-350019-4nlbu54e	477	1	The	the	DT
cord-350019-4nlbu54e	477	2	human	human	JJ
cord-350019-4nlbu54e	477	3	long	long	JJ
cord-350019-4nlbu54e	477	4	noncoding	noncoding	NNP
cord-350019-4nlbu54e	477	5	RNA	RNA	NNP
cord-350019-4nlbu54e	477	6	lnc	lnc	NNP
cord-350019-4nlbu54e	477	7	-	-	HYPH
cord-350019-4nlbu54e	477	8	IL7R	IL7R	NNP
cord-350019-4nlbu54e	477	9	regulates	regulate	VBZ
cord-350019-4nlbu54e	477	10	the	the	DT
cord-350019-4nlbu54e	477	11	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	477	12	response	response	NN
cord-350019-4nlbu54e	477	13	Corrigendum	Corrigendum	NNP
cord-350019-4nlbu54e	477	14	:	:	:
cord-350019-4nlbu54e	477	15	long	long	JJ
cord-350019-4nlbu54e	477	16	non	non	JJ
cord-350019-4nlbu54e	477	17	-	-	JJ
cord-350019-4nlbu54e	477	18	coding	coding	JJ
cord-350019-4nlbu54e	477	19	RNAs	rna	NNS
cord-350019-4nlbu54e	477	20	and	and	CC
cord-350019-4nlbu54e	477	21	enhancer	enhancer	NN
cord-350019-4nlbu54e	477	22	RNAs	rna	NNS
cord-350019-4nlbu54e	477	23	regulate	regulate	VBP
cord-350019-4nlbu54e	477	24	the	the	DT
cord-350019-4nlbu54e	477	25	lipopolysaccharide	lipopolysaccharide	NN
cord-350019-4nlbu54e	477	26	-	-	HYPH
cord-350019-4nlbu54e	477	27	induced	induce	VBN
cord-350019-4nlbu54e	477	28	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	477	29	response	response	NN
cord-350019-4nlbu54e	477	30	in	in	IN
cord-350019-4nlbu54e	477	31	human	human	JJ
cord-350019-4nlbu54e	477	32	monocytes	monocyte	NNS
cord-350019-4nlbu54e	477	33	Chromatin	Chromatin	NNP
cord-350019-4nlbu54e	477	34	signature	signature	NN
cord-350019-4nlbu54e	477	35	reveals	reveal	VBZ
cord-350019-4nlbu54e	477	36	over	over	IN
cord-350019-4nlbu54e	477	37	a	a	DT
cord-350019-4nlbu54e	477	38	thousand	thousand	CD
cord-350019-4nlbu54e	477	39	highly	highly	RB
cord-350019-4nlbu54e	477	40	conserved	conserved	JJ
cord-350019-4nlbu54e	477	41	large	large	JJ
cord-350019-4nlbu54e	477	42	non	non	JJ
cord-350019-4nlbu54e	477	43	-	-	JJ
cord-350019-4nlbu54e	477	44	coding	coding	JJ
cord-350019-4nlbu54e	477	45	RNAs	rna	NNS
cord-350019-4nlbu54e	477	46	in	in	IN
cord-350019-4nlbu54e	477	47	mammals	mammal	NNS
cord-350019-4nlbu54e	477	48	Genome	Genome	NNP
cord-350019-4nlbu54e	477	49	regulation	regulation	NN
cord-350019-4nlbu54e	477	50	by	by	IN
cord-350019-4nlbu54e	477	51	long	long	JJ
cord-350019-4nlbu54e	477	52	noncoding	noncoding	JJ
cord-350019-4nlbu54e	477	53	RNAs	rna	NNS
cord-350019-4nlbu54e	477	54	Cis	Cis	NNP
cord-350019-4nlbu54e	477	55	-	-	HYPH
cord-350019-4nlbu54e	477	56	and	and	CC
cord-350019-4nlbu54e	477	57	trans	trans	JJ
cord-350019-4nlbu54e	477	58	-	-	JJ
cord-350019-4nlbu54e	477	59	acting	act	VBG
cord-350019-4nlbu54e	477	60	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	477	61	in	in	IN
cord-350019-4nlbu54e	477	62	pluripotency	pluripotency	NN
cord-350019-4nlbu54e	477	63	and	and	CC
cord-350019-4nlbu54e	477	64	reprogramming	reprogramme	VBG
cord-350019-4nlbu54e	477	65	A	a	DT
cord-350019-4nlbu54e	477	66	long	long	JJ
cord-350019-4nlbu54e	477	67	noncoding	noncoding	JJ
cord-350019-4nlbu54e	477	68	RNA	RNA	NNP
cord-350019-4nlbu54e	477	69	lincRNA	lincRNA	NNP
cord-350019-4nlbu54e	477	70	-	-	HYPH
cord-350019-4nlbu54e	477	71	EPS	EPS	NNP
cord-350019-4nlbu54e	477	72	acts	act	VBZ
cord-350019-4nlbu54e	477	73	as	as	IN
cord-350019-4nlbu54e	477	74	a	a	DT
cord-350019-4nlbu54e	477	75	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	477	76	brake	brake	NN
cord-350019-4nlbu54e	477	77	to	to	TO
cord-350019-4nlbu54e	477	78	restrain	restrain	VB
cord-350019-4nlbu54e	477	79	inflammation	inflammation	NN
cord-350019-4nlbu54e	477	80	A	a	DT
cord-350019-4nlbu54e	477	81	long	long	JJ
cord-350019-4nlbu54e	477	82	noncoding	noncoding	JJ
cord-350019-4nlbu54e	477	83	RNA	rna	NN
cord-350019-4nlbu54e	477	84	associated	associate	VBN
cord-350019-4nlbu54e	477	85	with	with	IN
cord-350019-4nlbu54e	477	86	susceptibility	susceptibility	NN
cord-350019-4nlbu54e	477	87	to	to	IN
cord-350019-4nlbu54e	477	88	celiac	celiac	JJ
cord-350019-4nlbu54e	477	89	disease	disease	NN
cord-350019-4nlbu54e	477	90	,	,	,
cord-350019-4nlbu54e	477	91	Science	Science	NNP
cord-350019-4nlbu54e	477	92	(	(	-LRB-
cord-350019-4nlbu54e	477	93	80-	80-	CD
cord-350019-4nlbu54e	477	94	.	.	.
cord-350019-4nlbu54e	477	95	)	)	-RRB-
cord-350019-4nlbu54e	478	1	Immunobiology	Immunobiology	NNP
cord-350019-4nlbu54e	478	2	of	of	IN
cord-350019-4nlbu54e	478	3	long	long	JJ
cord-350019-4nlbu54e	478	4	noncoding	noncoding	JJ
cord-350019-4nlbu54e	478	5	RNAs	RNAs	NNPS
cord-350019-4nlbu54e	478	6	Cell	Cell	NNP
cord-350019-4nlbu54e	478	7	composition	composition	NN
cord-350019-4nlbu54e	478	8	analysis	analysis	NN
cord-350019-4nlbu54e	478	9	of	of	IN
cord-350019-4nlbu54e	478	10	bulk	bulk	JJ
cord-350019-4nlbu54e	478	11	genomics	genomic	NNS
cord-350019-4nlbu54e	478	12	using	use	VBG
cord-350019-4nlbu54e	478	13	single	single	JJ
cord-350019-4nlbu54e	478	14	-	-	HYPH
cord-350019-4nlbu54e	478	15	cell	cell	NN
cord-350019-4nlbu54e	478	16	data	datum	NNS
cord-350019-4nlbu54e	478	17	Innate	innate	VBP
cord-350019-4nlbu54e	478	18	immune	immune	JJ
cord-350019-4nlbu54e	478	19	landscape	landscape	NN
cord-350019-4nlbu54e	478	20	in	in	IN
cord-350019-4nlbu54e	478	21	early	early	JJ
cord-350019-4nlbu54e	478	22	lung	lung	NN
cord-350019-4nlbu54e	478	23	adenocarcinoma	adenocarcinoma	NN
cord-350019-4nlbu54e	478	24	by	by	IN
cord-350019-4nlbu54e	478	25	paired	pair	VBN
cord-350019-4nlbu54e	478	26	single	single	JJ
cord-350019-4nlbu54e	478	27	-	-	HYPH
cord-350019-4nlbu54e	478	28	cell	cell	NN
cord-350019-4nlbu54e	478	29	analyses	analysis	NNS
cord-350019-4nlbu54e	479	1	Single	single	JJ
cord-350019-4nlbu54e	479	2	cell	cell	NN
cord-350019-4nlbu54e	479	3	RNA	rna	NN
cord-350019-4nlbu54e	479	4	sequencing	sequencing	NN
cord-350019-4nlbu54e	479	5	of	of	IN
cord-350019-4nlbu54e	479	6	human	human	JJ
cord-350019-4nlbu54e	479	7	liver	liver	NN
cord-350019-4nlbu54e	479	8	reveals	reveal	VBZ
cord-350019-4nlbu54e	479	9	distinct	distinct	JJ
cord-350019-4nlbu54e	479	10	intrahepatic	intrahepatic	JJ
cord-350019-4nlbu54e	479	11	macrophage	macrophage	NN
cord-350019-4nlbu54e	479	12	populations	population	NNS
cord-350019-4nlbu54e	479	13	Single	single	JJ
cord-350019-4nlbu54e	479	14	-	-	HYPH
cord-350019-4nlbu54e	479	15	cell	cell	NN
cord-350019-4nlbu54e	479	16	analysis	analysis	NN
cord-350019-4nlbu54e	479	17	reveals	reveal	VBZ
cord-350019-4nlbu54e	479	18	that	that	IN
cord-350019-4nlbu54e	479	19	stochasticity	stochasticity	NN
cord-350019-4nlbu54e	479	20	and	and	CC
cord-350019-4nlbu54e	479	21	paracrine	paracrine	NN
cord-350019-4nlbu54e	479	22	signaling	signal	VBG
cord-350019-4nlbu54e	479	23	control	control	NN
cord-350019-4nlbu54e	479	24	interferon	interferon	NN
cord-350019-4nlbu54e	479	25	-	-	HYPH
cord-350019-4nlbu54e	479	26	alpha	alpha	NN
cord-350019-4nlbu54e	479	27	production	production	NN
cord-350019-4nlbu54e	479	28	by	by	IN
cord-350019-4nlbu54e	479	29	plasmacytoid	plasmacytoid	NNP
cord-350019-4nlbu54e	479	30	dendritic	dendritic	JJ
cord-350019-4nlbu54e	479	31	cells	cell	NNS
cord-350019-4nlbu54e	480	1	Seq	Seq	NNP
cord-350019-4nlbu54e	481	1	-Well	-well	UH
cord-350019-4nlbu54e	481	2	:	:	:
cord-350019-4nlbu54e	481	3	portable	portable	JJ
cord-350019-4nlbu54e	481	4	,	,	,
cord-350019-4nlbu54e	481	5	low	low	JJ
cord-350019-4nlbu54e	481	6	-	-	HYPH
cord-350019-4nlbu54e	481	7	cost	cost	NN
cord-350019-4nlbu54e	481	8	RNA	rna	NN
cord-350019-4nlbu54e	481	9	sequencing	sequencing	NN
cord-350019-4nlbu54e	481	10	of	of	IN
cord-350019-4nlbu54e	481	11	single	single	JJ
cord-350019-4nlbu54e	481	12	cells	cell	NNS
cord-350019-4nlbu54e	481	13	at	at	IN
cord-350019-4nlbu54e	481	14	high	high	JJ
cord-350019-4nlbu54e	481	15	throughput	throughput	NN
cord-350019-4nlbu54e	481	16	Unique	unique	JJ
cord-350019-4nlbu54e	481	17	signatures	signature	NNS
cord-350019-4nlbu54e	481	18	of	of	IN
cord-350019-4nlbu54e	481	19	long	long	JJ
cord-350019-4nlbu54e	481	20	noncoding	noncoding	JJ
cord-350019-4nlbu54e	481	21	RNA	RNA	NNP
cord-350019-4nlbu54e	481	22	expression	expression	NN
cord-350019-4nlbu54e	481	23	in	in	IN
cord-350019-4nlbu54e	481	24	response	response	NN
cord-350019-4nlbu54e	481	25	to	to	IN
cord-350019-4nlbu54e	481	26	virus	virus	NN
cord-350019-4nlbu54e	481	27	infection	infection	NN
cord-350019-4nlbu54e	481	28	and	and	CC
cord-350019-4nlbu54e	481	29	altered	alter	VBN
cord-350019-4nlbu54e	481	30	innate	innate	JJ
cord-350019-4nlbu54e	481	31	immune	immune	NN
cord-350019-4nlbu54e	481	32	signaling	signal	VBG
cord-350019-4nlbu54e	481	33	Digital	Digital	NNP
cord-350019-4nlbu54e	481	34	cell	cell	NN
cord-350019-4nlbu54e	481	35	quantification	quantification	NN
cord-350019-4nlbu54e	482	1	identifies	identify	VBZ
cord-350019-4nlbu54e	482	2	global	global	JJ
cord-350019-4nlbu54e	482	3	immune	immune	JJ
cord-350019-4nlbu54e	482	4	cell	cell	NN
cord-350019-4nlbu54e	482	5	dynamics	dynamic	NNS
cord-350019-4nlbu54e	482	6	during	during	IN
cord-350019-4nlbu54e	482	7	influenza	influenza	NN
cord-350019-4nlbu54e	482	8	infection	infection	NN
cord-350019-4nlbu54e	482	9	Chromatin	Chromatin	NNP
cord-350019-4nlbu54e	482	10	state	state	NN
cord-350019-4nlbu54e	482	11	dynamics	dynamic	NNS
cord-350019-4nlbu54e	482	12	during	during	IN
cord-350019-4nlbu54e	482	13	blood	blood	NN
cord-350019-4nlbu54e	482	14	formation	formation	NN
cord-350019-4nlbu54e	482	15	HHS	HHS	NNP
cord-350019-4nlbu54e	482	16	Public	Public	NNP
cord-350019-4nlbu54e	482	17	Access	Access	NNP
cord-350019-4nlbu54e	482	18	,	,	,
cord-350019-4nlbu54e	482	19	Science	Science	NNP
cord-350019-4nlbu54e	482	20	(	(	-LRB-
cord-350019-4nlbu54e	482	21	80-	80-	CD
cord-350019-4nlbu54e	482	22	.	.	.
cord-350019-4nlbu54e	482	23	)	)	-RRB-
cord-350019-4nlbu54e	483	1	Tissue	tissue	NN
cord-350019-4nlbu54e	483	2	-	-	HYPH
cord-350019-4nlbu54e	483	3	resident	resident	NN
cord-350019-4nlbu54e	483	4	macrophage	macrophage	NN
cord-350019-4nlbu54e	483	5	enhancer	enhancer	NN
cord-350019-4nlbu54e	483	6	landscapes	landscape	NNS
cord-350019-4nlbu54e	483	7	are	be	VBP
cord-350019-4nlbu54e	483	8	shaped	shape	VBN
cord-350019-4nlbu54e	483	9	by	by	IN
cord-350019-4nlbu54e	483	10	the	the	DT
cord-350019-4nlbu54e	483	11	local	local	JJ
cord-350019-4nlbu54e	483	12	microenvironment	microenvironment	NN
cord-350019-4nlbu54e	483	13	A	a	DT
cord-350019-4nlbu54e	483	14	Stringent	Stringent	NNP
cord-350019-4nlbu54e	483	15	Systems	Systems	NNPS
cord-350019-4nlbu54e	483	16	Approach	Approach	NNP
cord-350019-4nlbu54e	483	17	Uncovers	uncover	VBZ
cord-350019-4nlbu54e	483	18	Gene	gene	NN
cord-350019-4nlbu54e	483	19	-	-	HYPH
cord-350019-4nlbu54e	483	20	Specific	Specific	NNP
cord-350019-4nlbu54e	483	21	Mechanisms	Mechanisms	NNPS
cord-350019-4nlbu54e	483	22	Regulating	regulate	VBG
cord-350019-4nlbu54e	483	23	Inflammation	Inflammation	NNP
cord-350019-4nlbu54e	483	24	Analysis	Analysis	NNP
cord-350019-4nlbu54e	483	25	of	of	IN
cord-350019-4nlbu54e	483	26	genetically	genetically	RB
cord-350019-4nlbu54e	483	27	diverse	diverse	JJ
cord-350019-4nlbu54e	483	28	macrophages	macrophage	NNS
cord-350019-4nlbu54e	483	29	reveals	reveal	VBZ
cord-350019-4nlbu54e	483	30	local	local	JJ
cord-350019-4nlbu54e	483	31	and	and	CC
cord-350019-4nlbu54e	483	32	domain	domain	NN
cord-350019-4nlbu54e	483	33	-	-	HYPH
cord-350019-4nlbu54e	483	34	wide	wide	JJ
cord-350019-4nlbu54e	483	35	mechanisms	mechanism	NNS
cord-350019-4nlbu54e	483	36	that	that	WDT
cord-350019-4nlbu54e	483	37	control	control	VBP
cord-350019-4nlbu54e	483	38	transcription	transcription	NN
cord-350019-4nlbu54e	483	39	factor	factor	NN
cord-350019-4nlbu54e	483	40	binding	binding	NN
cord-350019-4nlbu54e	483	41	and	and	CC
cord-350019-4nlbu54e	483	42	function	function	NN
cord-350019-4nlbu54e	483	43	Transcript	Transcript	NNP
cord-350019-4nlbu54e	483	44	dynamics	dynamic	NNS
cord-350019-4nlbu54e	483	45	of	of	IN
cord-350019-4nlbu54e	483	46	proinflammatory	proinflammatory	JJ
cord-350019-4nlbu54e	483	47	genes	gene	NNS
cord-350019-4nlbu54e	483	48	revealed	reveal	VBN
cord-350019-4nlbu54e	483	49	by	by	IN
cord-350019-4nlbu54e	483	50	sequence	sequence	NN
cord-350019-4nlbu54e	483	51	analysis	analysis	NN
cord-350019-4nlbu54e	483	52	of	of	IN
cord-350019-4nlbu54e	483	53	subcellular	subcellular	JJ
cord-350019-4nlbu54e	483	54	RNA	RNA	NNP
cord-350019-4nlbu54e	483	55	fractions	fraction	NNS
cord-350019-4nlbu54e	483	56	Transcriptional	Transcriptional	NNP
cord-350019-4nlbu54e	483	57	landscape	landscape	NN
cord-350019-4nlbu54e	483	58	of	of	IN
cord-350019-4nlbu54e	483	59	Mycobacterium	Mycobacterium	NNP
cord-350019-4nlbu54e	483	60	tuberculosis	tuberculosis	NN
cord-350019-4nlbu54e	483	61	infection	infection	NN
cord-350019-4nlbu54e	483	62	in	in	IN
cord-350019-4nlbu54e	483	63	macrophages	macrophage	NNS
cord-350019-4nlbu54e	484	1	A	a	DT
cord-350019-4nlbu54e	484	2	stringent	stringent	JJ
cord-350019-4nlbu54e	484	3	systems	system	NNS
cord-350019-4nlbu54e	484	4	approach	approach	NN
cord-350019-4nlbu54e	484	5	uncovers	uncover	VBZ
cord-350019-4nlbu54e	484	6	gene	gene	NN
cord-350019-4nlbu54e	484	7	-	-	HYPH
cord-350019-4nlbu54e	484	8	specific	specific	JJ
cord-350019-4nlbu54e	484	9	mechanisms	mechanism	NNS
cord-350019-4nlbu54e	484	10	regulating	regulate	VBG
cord-350019-4nlbu54e	485	1	inflammation	inflammation	NN
cord-350019-4nlbu54e	485	2	Tissue	tissue	NN
cord-350019-4nlbu54e	485	3	damage	damage	NN
cord-350019-4nlbu54e	485	4	drives	drive	NNS
cord-350019-4nlbu54e	485	5	co	co	NN
cord-350019-4nlbu54e	485	6	-	-	NN
cord-350019-4nlbu54e	485	7	localization	localization	NN
cord-350019-4nlbu54e	485	8	of	of	IN
cord-350019-4nlbu54e	485	9	NF	nf	NN
cord-350019-4nlbu54e	485	10	-	-	HYPH
cord-350019-4nlbu54e	485	11	κB	κB	NNP
cord-350019-4nlbu54e	485	12	,	,	,
cord-350019-4nlbu54e	485	13	Smad3	Smad3	NNP
cord-350019-4nlbu54e	485	14	,	,	,
cord-350019-4nlbu54e	485	15	and	and	CC
cord-350019-4nlbu54e	485	16	Nrf2	Nrf2	NNP
cord-350019-4nlbu54e	486	1	to	to	TO
cord-350019-4nlbu54e	486	2	direct	direct	VB
cord-350019-4nlbu54e	486	3	Rev	Rev	NNP
cord-350019-4nlbu54e	486	4	-	-	HYPH
cord-350019-4nlbu54e	486	5	erb	erb	NNP
cord-350019-4nlbu54e	486	6	sensitive	sensitive	JJ
cord-350019-4nlbu54e	486	7	wound	wound	NN
cord-350019-4nlbu54e	486	8	repair	repair	NN
cord-350019-4nlbu54e	486	9	in	in	IN
cord-350019-4nlbu54e	486	10	mouse	mouse	NN
cord-350019-4nlbu54e	486	11	macrophages	macrophage	NNS
cord-350019-4nlbu54e	487	1	Widespread	widespread	JJ
cord-350019-4nlbu54e	487	2	shortening	shortening	NN
cord-350019-4nlbu54e	487	3	of	of	IN
cord-350019-4nlbu54e	487	4	3′	3′	CD
cord-350019-4nlbu54e	487	5	untranslated	untranslated	JJ
cord-350019-4nlbu54e	487	6	regions	region	NNS
cord-350019-4nlbu54e	487	7	and	and	CC
cord-350019-4nlbu54e	487	8	increased	increase	VBN
cord-350019-4nlbu54e	487	9	exon	exon	NN
cord-350019-4nlbu54e	487	10	inclusion	inclusion	NN
cord-350019-4nlbu54e	487	11	are	be	VBP
cord-350019-4nlbu54e	487	12	evolutionarily	evolutionarily	RB
cord-350019-4nlbu54e	487	13	conserved	conserve	VBN
cord-350019-4nlbu54e	487	14	features	feature	NNS
cord-350019-4nlbu54e	487	15	of	of	IN
cord-350019-4nlbu54e	487	16	innate	innate	JJ
cord-350019-4nlbu54e	487	17	immune	immune	JJ
cord-350019-4nlbu54e	487	18	responses	response	NNS
cord-350019-4nlbu54e	487	19	to	to	IN
cord-350019-4nlbu54e	487	20	infection	infection	NN
cord-350019-4nlbu54e	488	1	The	the	DT
cord-350019-4nlbu54e	488	2	STAT3-binding	STAT3-binding	NNP
cord-350019-4nlbu54e	488	3	long	long	RB
cord-350019-4nlbu54e	488	4	noncoding	noncoding	JJ
cord-350019-4nlbu54e	488	5	RNA	RNA	NNP
cord-350019-4nlbu54e	488	6	lnc	lnc	NNP
cord-350019-4nlbu54e	488	7	-	-	HYPH
cord-350019-4nlbu54e	488	8	DC	DC	NNP
cord-350019-4nlbu54e	488	9	controls	control	VBZ
cord-350019-4nlbu54e	488	10	human	human	JJ
cord-350019-4nlbu54e	488	11	dendritic	dendritic	JJ
cord-350019-4nlbu54e	488	12	cell	cell	NN
cord-350019-4nlbu54e	488	13	differentiation	differentiation	NN
cord-350019-4nlbu54e	488	14	Epigenetic	epigenetic	JJ
cord-350019-4nlbu54e	488	15	programming	programming	NN
cord-350019-4nlbu54e	488	16	of	of	IN
cord-350019-4nlbu54e	488	17	monocyte	monocyte	NNP
cord-350019-4nlbu54e	488	18	-	-	HYPH
cord-350019-4nlbu54e	488	19	to	to	IN
cord-350019-4nlbu54e	488	20	-	-	HYPH
cord-350019-4nlbu54e	488	21	macrophage	macrophage	NN
cord-350019-4nlbu54e	488	22	differentiation	differentiation	NN
cord-350019-4nlbu54e	488	23	and	and	CC
cord-350019-4nlbu54e	488	24	trained	train	VBN
cord-350019-4nlbu54e	488	25	innate	innate	JJ
cord-350019-4nlbu54e	488	26	immunity	immunity	NN
cord-350019-4nlbu54e	488	27	β	β	NN
cord-350019-4nlbu54e	488	28	-	-	:
cord-350019-4nlbu54e	488	29	Glucan	Glucan	NNP
cord-350019-4nlbu54e	488	30	reverses	reverse	VBZ
cord-350019-4nlbu54e	488	31	the	the	DT
cord-350019-4nlbu54e	488	32	epigenetic	epigenetic	JJ
cord-350019-4nlbu54e	488	33	state	state	NN
cord-350019-4nlbu54e	488	34	of	of	IN
cord-350019-4nlbu54e	488	35	LPS	LPS	NNP
cord-350019-4nlbu54e	488	36	-	-	HYPH
cord-350019-4nlbu54e	488	37	induced	induce	VBN
cord-350019-4nlbu54e	488	38	immunological	immunological	JJ
cord-350019-4nlbu54e	488	39	tolerance	tolerance	NN
cord-350019-4nlbu54e	489	1	Specific	specific	JJ
cord-350019-4nlbu54e	489	2	and	and	CC
cord-350019-4nlbu54e	489	3	novel	novel	JJ
cord-350019-4nlbu54e	490	1	microRNAs	microrna	NNS
cord-350019-4nlbu54e	490	2	are	be	VBP
cord-350019-4nlbu54e	490	3	regulated	regulate	VBN
cord-350019-4nlbu54e	490	4	as	as	IN
cord-350019-4nlbu54e	490	5	response	response	NN
cord-350019-4nlbu54e	490	6	to	to	IN
cord-350019-4nlbu54e	490	7	fungal	fungal	JJ
cord-350019-4nlbu54e	490	8	infection	infection	NN
cord-350019-4nlbu54e	490	9	in	in	IN
cord-350019-4nlbu54e	490	10	human	human	JJ
cord-350019-4nlbu54e	490	11	dendritic	dendritic	JJ
cord-350019-4nlbu54e	490	12	cells	cell	NNS
cord-350019-4nlbu54e	491	1	An	an	DT
cord-350019-4nlbu54e	491	2	interferon	interferon	NN
cord-350019-4nlbu54e	491	3	-	-	HYPH
cord-350019-4nlbu54e	491	4	related	relate	VBN
cord-350019-4nlbu54e	491	5	signature	signature	NN
cord-350019-4nlbu54e	491	6	in	in	IN
cord-350019-4nlbu54e	491	7	the	the	DT
cord-350019-4nlbu54e	491	8	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	491	9	core	core	NN
cord-350019-4nlbu54e	491	10	response	response	NN
cord-350019-4nlbu54e	491	11	of	of	IN
cord-350019-4nlbu54e	491	12	human	human	JJ
cord-350019-4nlbu54e	491	13	macrophages	macrophage	NNS
cord-350019-4nlbu54e	491	14	to	to	IN
cord-350019-4nlbu54e	491	15	Mycobacterium	Mycobacterium	NNP
cord-350019-4nlbu54e	491	16	tuberculosis	tuberculosis	NN
cord-350019-4nlbu54e	491	17	infection	infection	NN
cord-350019-4nlbu54e	492	1	The	the	DT
cord-350019-4nlbu54e	492	2	long	long	JJ
cord-350019-4nlbu54e	492	3	noncoding	noncoding	JJ
cord-350019-4nlbu54e	492	4	RNA	RNA	NNP
cord-350019-4nlbu54e	492	5	THRIL	THRIL	NNP
cord-350019-4nlbu54e	492	6	regulates	regulate	VBZ
cord-350019-4nlbu54e	492	7	TNFα	TNFα	NNP
cord-350019-4nlbu54e	492	8	expression	expression	NN
cord-350019-4nlbu54e	492	9	through	through	IN
cord-350019-4nlbu54e	492	10	its	-PRON-	PRP$
cord-350019-4nlbu54e	492	11	interaction	interaction	NN
cord-350019-4nlbu54e	492	12	with	with	IN
cord-350019-4nlbu54e	492	13	hnRNPL	hnrnpl	ADD
cord-350019-4nlbu54e	492	14	Catalog	Catalog	NNP
cord-350019-4nlbu54e	492	15	of	of	IN
cord-350019-4nlbu54e	492	16	differentially	differentially	RB
cord-350019-4nlbu54e	492	17	expressed	express	VBN
cord-350019-4nlbu54e	492	18	long	long	JJ
cord-350019-4nlbu54e	492	19	non	non	JJ
cord-350019-4nlbu54e	492	20	-	-	JJ
cord-350019-4nlbu54e	492	21	coding	code	VBG
cord-350019-4nlbu54e	492	22	RNA	rna	NN
cord-350019-4nlbu54e	492	23	following	follow	VBG
cord-350019-4nlbu54e	492	24	activation	activation	NN
cord-350019-4nlbu54e	492	25	of	of	IN
cord-350019-4nlbu54e	492	26	human	human	NN
cord-350019-4nlbu54e	492	27	and	and	CC
cord-350019-4nlbu54e	492	28	mouse	mouse	NN
cord-350019-4nlbu54e	492	29	innate	innate	JJ
cord-350019-4nlbu54e	492	30	immune	immune	JJ
cord-350019-4nlbu54e	492	31	response	response	NN
cord-350019-4nlbu54e	493	1	Whole	whole	JJ
cord-350019-4nlbu54e	493	2	transcriptome	transcriptome	NN
cord-350019-4nlbu54e	493	3	analysis	analysis	NN
cord-350019-4nlbu54e	493	4	reveals	reveal	VBZ
cord-350019-4nlbu54e	493	5	differential	differential	JJ
cord-350019-4nlbu54e	493	6	gene	gene	NN
cord-350019-4nlbu54e	493	7	expression	expression	NN
cord-350019-4nlbu54e	493	8	profile	profile	NN
cord-350019-4nlbu54e	493	9	reflecting	reflect	VBG
cord-350019-4nlbu54e	493	10	macrophage	macrophage	NN
cord-350019-4nlbu54e	493	11	polarization	polarization	NN
cord-350019-4nlbu54e	493	12	in	in	IN
cord-350019-4nlbu54e	493	13	response	response	NN
cord-350019-4nlbu54e	493	14	to	to	TO
cord-350019-4nlbu54e	493	15	influenza	influenza	VB
cord-350019-4nlbu54e	493	16	A	a	DT
cord-350019-4nlbu54e	493	17	H5N1	H5N1	NNP
cord-350019-4nlbu54e	493	18	virus	virus	NN
cord-350019-4nlbu54e	493	19	infection	infection	NN
cord-350019-4nlbu54e	493	20	Human	human	JJ
cord-350019-4nlbu54e	493	21	body	body	NN
cord-350019-4nlbu54e	493	22	epigenome	epigenome	NN
cord-350019-4nlbu54e	493	23	maps	map	NNS
cord-350019-4nlbu54e	493	24	reveal	reveal	VBP
cord-350019-4nlbu54e	493	25	noncanonical	noncanonical	JJ
cord-350019-4nlbu54e	493	26	DNA	dna	NN
cord-350019-4nlbu54e	493	27	methylation	methylation	NN
cord-350019-4nlbu54e	493	28	variation	variation	NN
cord-350019-4nlbu54e	493	29	Infectious	infectious	JJ
cord-350019-4nlbu54e	493	30	disease	disease	NN
cord-350019-4nlbu54e	493	31	.	.	.
cord-350019-4nlbu54e	494	1	Life	life	NN
cord-350019-4nlbu54e	494	2	-	-	HYPH
cord-350019-4nlbu54e	494	3	threatening	threaten	VBG
cord-350019-4nlbu54e	494	4	influenza	influenza	NN
cord-350019-4nlbu54e	494	5	and	and	CC
cord-350019-4nlbu54e	494	6	impaired	impair	VBN
cord-350019-4nlbu54e	494	7	interferon	interferon	NN
cord-350019-4nlbu54e	494	8	amplification	amplification	NN
cord-350019-4nlbu54e	494	9	in	in	IN
cord-350019-4nlbu54e	494	10	human	human	JJ
cord-350019-4nlbu54e	494	11	IRF7	IRF7	NNP
cord-350019-4nlbu54e	494	12	deficiency	deficiency	NN
cord-350019-4nlbu54e	494	13	Longitudinal	longitudinal	JJ
cord-350019-4nlbu54e	494	14	profiling	profiling	NN
cord-350019-4nlbu54e	494	15	of	of	IN
cord-350019-4nlbu54e	494	16	human	human	JJ
cord-350019-4nlbu54e	494	17	blood	blood	NN
cord-350019-4nlbu54e	494	18	transcriptome	transcriptome	NN
cord-350019-4nlbu54e	494	19	in	in	IN
cord-350019-4nlbu54e	494	20	healthy	healthy	JJ
cord-350019-4nlbu54e	494	21	and	and	CC
cord-350019-4nlbu54e	494	22	lupus	lupus	JJ
cord-350019-4nlbu54e	494	23	pregnancy	pregnancy	NN
cord-350019-4nlbu54e	495	1	The	the	DT
cord-350019-4nlbu54e	495	2	accessible	accessible	JJ
cord-350019-4nlbu54e	495	3	chromatin	chromatin	NN
cord-350019-4nlbu54e	495	4	landscape	landscape	NN
cord-350019-4nlbu54e	495	5	of	of	IN
cord-350019-4nlbu54e	495	6	the	the	DT
cord-350019-4nlbu54e	495	7	human	human	JJ
cord-350019-4nlbu54e	495	8	genome	genome	NN
cord-350019-4nlbu54e	495	9	EVLncRNAs	EVLncRNAs	NNP
cord-350019-4nlbu54e	495	10	:	:	:
cord-350019-4nlbu54e	495	11	a	a	DT
cord-350019-4nlbu54e	495	12	manually	manually	RB
cord-350019-4nlbu54e	495	13	curated	curate	VBN
cord-350019-4nlbu54e	495	14	database	database	NN
cord-350019-4nlbu54e	495	15	for	for	IN
cord-350019-4nlbu54e	495	16	long	long	JJ
cord-350019-4nlbu54e	495	17	non	non	JJ
cord-350019-4nlbu54e	495	18	-	-	JJ
cord-350019-4nlbu54e	495	19	coding	coding	JJ
cord-350019-4nlbu54e	495	20	RNAs	rna	NNS
cord-350019-4nlbu54e	495	21	validated	validate	VBN
cord-350019-4nlbu54e	495	22	by	by	IN
cord-350019-4nlbu54e	495	23	low	low	JJ
cord-350019-4nlbu54e	495	24	-	-	HYPH
cord-350019-4nlbu54e	495	25	throughput	throughput	NN
cord-350019-4nlbu54e	495	26	experiments	experiment	NNS
cord-350019-4nlbu54e	496	1	NONCODEV5	NONCODEV5	VBN
cord-350019-4nlbu54e	496	2	:	:	:
cord-350019-4nlbu54e	497	1	a	a	DT
cord-350019-4nlbu54e	497	2	comprehensive	comprehensive	JJ
cord-350019-4nlbu54e	497	3	annotation	annotation	NN
cord-350019-4nlbu54e	497	4	database	database	NN
cord-350019-4nlbu54e	497	5	for	for	IN
cord-350019-4nlbu54e	497	6	long	long	JJ
cord-350019-4nlbu54e	497	7	noncoding	noncoding	JJ
cord-350019-4nlbu54e	497	8	RNAs	rna	NNS
cord-350019-4nlbu54e	497	9	LNCipedia	LNCipedia	NNP
cord-350019-4nlbu54e	497	10	5	5	CD
cord-350019-4nlbu54e	497	11	:	:	:
cord-350019-4nlbu54e	497	12	towards	towards	IN
cord-350019-4nlbu54e	497	13	a	a	DT
cord-350019-4nlbu54e	497	14	reference	reference	NN
cord-350019-4nlbu54e	497	15	set	set	VBN
cord-350019-4nlbu54e	497	16	of	of	IN
cord-350019-4nlbu54e	497	17	human	human	JJ
cord-350019-4nlbu54e	497	18	long	long	JJ
cord-350019-4nlbu54e	497	19	noncoding	noncoding	JJ
cord-350019-4nlbu54e	497	20	RNAs	RNAs	NNPS
cord-350019-4nlbu54e	497	21	Landscape	Landscape	NNP
cord-350019-4nlbu54e	497	22	of	of	IN
cord-350019-4nlbu54e	497	23	transcription	transcription	NN
cord-350019-4nlbu54e	497	24	in	in	IN
cord-350019-4nlbu54e	497	25	human	human	JJ
cord-350019-4nlbu54e	497	26	cells	cell	NNS
cord-350019-4nlbu54e	497	27	Integrative	integrative	JJ
cord-350019-4nlbu54e	497	28	annotation	annotation	NN
cord-350019-4nlbu54e	497	29	of	of	IN
cord-350019-4nlbu54e	497	30	human	human	JJ
cord-350019-4nlbu54e	497	31	large	large	JJ
cord-350019-4nlbu54e	497	32	intergenic	intergenic	JJ
cord-350019-4nlbu54e	497	33	noncoding	noncoding	JJ
cord-350019-4nlbu54e	497	34	RNAs	rna	NNS
cord-350019-4nlbu54e	497	35	reveals	reveal	VBZ
cord-350019-4nlbu54e	497	36	global	global	JJ
cord-350019-4nlbu54e	497	37	properties	property	NNS
cord-350019-4nlbu54e	497	38	and	and	CC
cord-350019-4nlbu54e	497	39	specific	specific	JJ
cord-350019-4nlbu54e	497	40	subclasses	subclass	NNS
cord-350019-4nlbu54e	497	41	CRISPRi	crispri	NN
cord-350019-4nlbu54e	497	42	-	-	HYPH
cord-350019-4nlbu54e	497	43	based	base	VBN
cord-350019-4nlbu54e	497	44	genome	genome	NN
cord-350019-4nlbu54e	497	45	-	-	HYPH
cord-350019-4nlbu54e	497	46	scale	scale	NN
cord-350019-4nlbu54e	497	47	identification	identification	NN
cord-350019-4nlbu54e	497	48	of	of	IN
cord-350019-4nlbu54e	497	49	functional	functional	JJ
cord-350019-4nlbu54e	497	50	long	long	JJ
cord-350019-4nlbu54e	497	51	noncoding	noncoding	JJ
cord-350019-4nlbu54e	497	52	RNA	RNA	NNP
cord-350019-4nlbu54e	497	53	loci	locus	NNS
cord-350019-4nlbu54e	497	54	in	in	IN
cord-350019-4nlbu54e	497	55	human	human	JJ
cord-350019-4nlbu54e	497	56	cells	cell	NNS
cord-350019-4nlbu54e	497	57	Genetic	genetic	JJ
cord-350019-4nlbu54e	497	58	effects	effect	NNS
cord-350019-4nlbu54e	497	59	on	on	IN
cord-350019-4nlbu54e	497	60	gene	gene	NN
cord-350019-4nlbu54e	497	61	expression	expression	NN
cord-350019-4nlbu54e	497	62	across	across	IN
cord-350019-4nlbu54e	497	63	human	human	JJ
cord-350019-4nlbu54e	497	64	tissues	tissue	NNS
cord-350019-4nlbu54e	498	1	The	the	DT
cord-350019-4nlbu54e	498	2	UCSC	UCSC	NNP
cord-350019-4nlbu54e	498	3	Xena	Xena	NNP
cord-350019-4nlbu54e	498	4	Platform	Platform	NNP
cord-350019-4nlbu54e	498	5	for	for	IN
cord-350019-4nlbu54e	498	6	cancer	cancer	NN
cord-350019-4nlbu54e	498	7	genomics	genomic	NNS
cord-350019-4nlbu54e	498	8	data	datum	NNS
cord-350019-4nlbu54e	498	9	visualization	visualization	NN
cord-350019-4nlbu54e	498	10	and	and	CC
cord-350019-4nlbu54e	498	11	interpretation	interpretation	NN
cord-350019-4nlbu54e	498	12	Mapping	map	VBG
cord-350019-4nlbu54e	498	13	the	the	DT
cord-350019-4nlbu54e	498	14	Mouse	Mouse	NNP
cord-350019-4nlbu54e	498	15	Cell	Cell	NNP
cord-350019-4nlbu54e	498	16	Atlas	Atlas	NNP
cord-350019-4nlbu54e	498	17	by	by	IN
cord-350019-4nlbu54e	498	18	Microwell	Microwell	NNP
cord-350019-4nlbu54e	498	19	-	-	HYPH
cord-350019-4nlbu54e	498	20	Seq	Seq	NNP
cord-350019-4nlbu54e	498	21	Single	single	JJ
cord-350019-4nlbu54e	498	22	-	-	HYPH
cord-350019-4nlbu54e	498	23	cell	cell	NN
cord-350019-4nlbu54e	498	24	transcriptomics	transcriptomic	NNS
cord-350019-4nlbu54e	498	25	of	of	IN
cord-350019-4nlbu54e	498	26	20	20	CD
cord-350019-4nlbu54e	498	27	mouse	mouse	NN
cord-350019-4nlbu54e	498	28	organs	organ	NNS
cord-350019-4nlbu54e	498	29	creates	create	VBZ
cord-350019-4nlbu54e	498	30	a	a	DT
cord-350019-4nlbu54e	498	31	Tabula	Tabula	NNP
cord-350019-4nlbu54e	498	32	Muris	Muris	NNP
cord-350019-4nlbu54e	498	33	The	the	DT
cord-350019-4nlbu54e	498	34	Encyclopedia	Encyclopedia	NNP
cord-350019-4nlbu54e	498	35	of	of	IN
cord-350019-4nlbu54e	498	36	DNA	dna	NN
cord-350019-4nlbu54e	498	37	elements	element	NNS
cord-350019-4nlbu54e	498	38	(	(	-LRB-
cord-350019-4nlbu54e	498	39	ENCODE	encode	VB
cord-350019-4nlbu54e	498	40	)	)	-RRB-
cord-350019-4nlbu54e	499	1	:	:	:
cord-350019-4nlbu54e	499	2	data	data	NN
cord-350019-4nlbu54e	499	3	portal	portal	NNP
cord-350019-4nlbu54e	499	4	update	update	NN
cord-350019-4nlbu54e	499	5	Paradigm	Paradigm	NNP
cord-350019-4nlbu54e	499	6	shifts	shift	NNS
cord-350019-4nlbu54e	499	7	in	in	IN
cord-350019-4nlbu54e	499	8	genomics	genomic	NNS
cord-350019-4nlbu54e	499	9	through	through	IN
cord-350019-4nlbu54e	499	10	the	the	DT
cord-350019-4nlbu54e	499	11	FANTOM	FANTOM	NNP
cord-350019-4nlbu54e	499	12	projects	project	NNS
cord-350019-4nlbu54e	499	13	Chapter	Chapter	NNP
cord-350019-4nlbu54e	499	14	11	11	CD
cord-350019-4nlbu54e	499	15	:	:	:
cord-350019-4nlbu54e	499	16	genome	genome	NN
cord-350019-4nlbu54e	499	17	-	-	HYPH
cord-350019-4nlbu54e	499	18	wide	wide	JJ
cord-350019-4nlbu54e	499	19	association	association	NN
cord-350019-4nlbu54e	499	20	studies	study	NNS
cord-350019-4nlbu54e	499	21	10	10	CD
cord-350019-4nlbu54e	499	22	years	year	NNS
cord-350019-4nlbu54e	499	23	of	of	IN
cord-350019-4nlbu54e	499	24	GWAS	GWAS	NNP
cord-350019-4nlbu54e	499	25	discovery	discovery	NN
cord-350019-4nlbu54e	499	26	:	:	:
cord-350019-4nlbu54e	499	27	biology	biology	NN
cord-350019-4nlbu54e	499	28	,	,	,
cord-350019-4nlbu54e	499	29	function	function	NN
cord-350019-4nlbu54e	499	30	,	,	,
cord-350019-4nlbu54e	499	31	and	and	CC
cord-350019-4nlbu54e	499	32	translation	translation	NN
cord-350019-4nlbu54e	500	1	The	the	DT
cord-350019-4nlbu54e	500	2	contribution	contribution	NN
cord-350019-4nlbu54e	500	3	of	of	IN
cord-350019-4nlbu54e	500	4	genetic	genetic	JJ
cord-350019-4nlbu54e	500	5	variants	variant	NNS
cord-350019-4nlbu54e	500	6	to	to	IN
cord-350019-4nlbu54e	500	7	disease	disease	NN
cord-350019-4nlbu54e	500	8	depends	depend	VBZ
cord-350019-4nlbu54e	500	9	on	on	IN
cord-350019-4nlbu54e	500	10	the	the	DT
cord-350019-4nlbu54e	500	11	ruler	ruler	NN
cord-350019-4nlbu54e	500	12	Human	human	JJ
cord-350019-4nlbu54e	500	13	disease	disease	NN
cord-350019-4nlbu54e	500	14	-	-	HYPH
cord-350019-4nlbu54e	500	15	associated	associate	VBN
cord-350019-4nlbu54e	500	16	genetic	genetic	JJ
cord-350019-4nlbu54e	500	17	variation	variation	NN
cord-350019-4nlbu54e	500	18	impacts	impact	VBZ
cord-350019-4nlbu54e	500	19	large	large	JJ
cord-350019-4nlbu54e	500	20	intergenic	intergenic	JJ
cord-350019-4nlbu54e	500	21	non	non	JJ
cord-350019-4nlbu54e	500	22	-	-	JJ
cord-350019-4nlbu54e	500	23	coding	coding	JJ
cord-350019-4nlbu54e	500	24	RNA	rna	NN
cord-350019-4nlbu54e	500	25	expression	expression	NN
cord-350019-4nlbu54e	501	1	The	the	DT
cord-350019-4nlbu54e	501	2	UK	UK	NNP
cord-350019-4nlbu54e	501	3	Biobank	Biobank	NNP
cord-350019-4nlbu54e	501	4	resource	resource	NN
cord-350019-4nlbu54e	501	5	with	with	IN
cord-350019-4nlbu54e	501	6	deep	deep	JJ
cord-350019-4nlbu54e	501	7	phenotyping	phenotyping	NN
cord-350019-4nlbu54e	501	8	and	and	CC
cord-350019-4nlbu54e	501	9	genomic	genomic	JJ
cord-350019-4nlbu54e	501	10	data	datum	NNS
cord-350019-4nlbu54e	501	11	Genome	Genome	NNP
cord-350019-4nlbu54e	501	12	-	-	HYPH
cord-350019-4nlbu54e	501	13	wide	wide	JJ
cord-350019-4nlbu54e	501	14	association	association	NN
cord-350019-4nlbu54e	501	15	studies	study	NNS
cord-350019-4nlbu54e	501	16	and	and	CC
cord-350019-4nlbu54e	501	17	beyond	beyond	IN
cord-350019-4nlbu54e	501	18	LncRNASNP2	LncRNASNP2	NNP
cord-350019-4nlbu54e	501	19	:	:	:
cord-350019-4nlbu54e	501	20	an	an	DT
cord-350019-4nlbu54e	501	21	updated	update	VBN
cord-350019-4nlbu54e	501	22	database	database	NN
cord-350019-4nlbu54e	501	23	of	of	IN
cord-350019-4nlbu54e	501	24	functional	functional	JJ
cord-350019-4nlbu54e	501	25	SNPs	snp	NNS
cord-350019-4nlbu54e	501	26	and	and	CC
cord-350019-4nlbu54e	501	27	mutations	mutation	NNS
cord-350019-4nlbu54e	501	28	in	in	IN
cord-350019-4nlbu54e	501	29	human	human	NN
cord-350019-4nlbu54e	501	30	and	and	CC
cord-350019-4nlbu54e	501	31	mouse	mouse	NN
cord-350019-4nlbu54e	502	1	lncRNAs	lncrnas	IN
cord-350019-4nlbu54e	502	2	Lnc2Catlas	Lnc2Catlas	NNP
cord-350019-4nlbu54e	502	3	:	:	:
cord-350019-4nlbu54e	502	4	an	an	DT
cord-350019-4nlbu54e	502	5	atlas	atlas	NNP
cord-350019-4nlbu54e	502	6	of	of	IN
cord-350019-4nlbu54e	502	7	long	long	JJ
cord-350019-4nlbu54e	502	8	noncoding	noncoding	JJ
cord-350019-4nlbu54e	502	9	RNAs	rna	NNS
cord-350019-4nlbu54e	502	10	associated	associate	VBN
cord-350019-4nlbu54e	502	11	with	with	IN
cord-350019-4nlbu54e	502	12	risk	risk	NN
cord-350019-4nlbu54e	502	13	of	of	IN
cord-350019-4nlbu54e	502	14	cancers	cancer	NNS
cord-350019-4nlbu54e	503	1	Long	Long	NNP
cord-350019-4nlbu54e	503	2	noncoding	noncoding	NNP
cord-350019-4nlbu54e	503	3	RNA	RNA	NNP
cord-350019-4nlbu54e	504	1	LINC00305	LINC00305	NNP
cord-350019-4nlbu54e	504	2	promotes	promote	VBZ
cord-350019-4nlbu54e	504	3	inflammation	inflammation	NN
cord-350019-4nlbu54e	504	4	by	by	IN
cord-350019-4nlbu54e	504	5	activating	activate	VBG
cord-350019-4nlbu54e	504	6	the	the	DT
cord-350019-4nlbu54e	504	7	AHRR	AHRR	NNP
cord-350019-4nlbu54e	504	8	-	-	HYPH
cord-350019-4nlbu54e	504	9	NF	NF	NNP
cord-350019-4nlbu54e	504	10	-	-	HYPH
cord-350019-4nlbu54e	504	11	k	k	NN
cord-350019-4nlbu54e	504	12	B	B	NNP
cord-350019-4nlbu54e	504	13	pathway	pathway	NN
cord-350019-4nlbu54e	504	14	in	in	IN
cord-350019-4nlbu54e	504	15	human	human	JJ
cord-350019-4nlbu54e	504	16	monocytes	monocyte	NNS
cord-350019-4nlbu54e	504	17	Disease	Disease	NNP
cord-350019-4nlbu54e	504	18	-	-	HYPH
cord-350019-4nlbu54e	504	19	associated	associate	VBN
cord-350019-4nlbu54e	504	20	SNPs	snp	NNS
cord-350019-4nlbu54e	504	21	in	in	IN
cord-350019-4nlbu54e	504	22	inflammation	inflammation	NN
cord-350019-4nlbu54e	504	23	-	-	HYPH
cord-350019-4nlbu54e	504	24	related	relate	VBN
cord-350019-4nlbu54e	504	25	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	504	26	PhyloCSF	PhyloCSF	NNP
cord-350019-4nlbu54e	504	27	:	:	:
cord-350019-4nlbu54e	505	1	a	a	DT
cord-350019-4nlbu54e	505	2	comparative	comparative	JJ
cord-350019-4nlbu54e	505	3	genomics	genomic	NNS
cord-350019-4nlbu54e	505	4	method	method	NN
cord-350019-4nlbu54e	505	5	to	to	TO
cord-350019-4nlbu54e	505	6	distinguish	distinguish	VB
cord-350019-4nlbu54e	505	7	protein	protein	NN
cord-350019-4nlbu54e	505	8	coding	code	VBG
cord-350019-4nlbu54e	505	9	and	and	CC
cord-350019-4nlbu54e	505	10	non	non	JJ
cord-350019-4nlbu54e	505	11	-	-	JJ
cord-350019-4nlbu54e	505	12	coding	coding	JJ
cord-350019-4nlbu54e	505	13	regions	region	NNS
cord-350019-4nlbu54e	505	14	Evolutionary	evolutionary	JJ
cord-350019-4nlbu54e	505	15	conservation	conservation	NN
cord-350019-4nlbu54e	505	16	of	of	IN
cord-350019-4nlbu54e	505	17	long	long	JJ
cord-350019-4nlbu54e	505	18	non	non	JJ
cord-350019-4nlbu54e	505	19	-	-	JJ
cord-350019-4nlbu54e	505	20	coding	coding	JJ
cord-350019-4nlbu54e	505	21	RNAs	rna	NNS
cord-350019-4nlbu54e	505	22	;	;	:
cord-350019-4nlbu54e	505	23	sequence	sequence	NN
cord-350019-4nlbu54e	505	24	,	,	,
cord-350019-4nlbu54e	505	25	structure	structure	NN
cord-350019-4nlbu54e	505	26	,	,	,
cord-350019-4nlbu54e	505	27	function	function	VB
cord-350019-4nlbu54e	505	28	Unique	unique	JJ
cord-350019-4nlbu54e	505	29	features	feature	NNS
cord-350019-4nlbu54e	505	30	of	of	IN
cord-350019-4nlbu54e	505	31	long	long	JJ
cord-350019-4nlbu54e	505	32	non	non	JJ
cord-350019-4nlbu54e	505	33	-	-	JJ
cord-350019-4nlbu54e	505	34	coding	coding	JJ
cord-350019-4nlbu54e	505	35	RNA	rna	NN
cord-350019-4nlbu54e	505	36	biogenesis	biogenesis	NN
cord-350019-4nlbu54e	505	37	and	and	CC
cord-350019-4nlbu54e	505	38	function	function	VB
cord-350019-4nlbu54e	505	39	Perspectives	perspective	NNS
cord-350019-4nlbu54e	505	40	on	on	IN
cord-350019-4nlbu54e	505	41	the	the	DT
cord-350019-4nlbu54e	505	42	mechanism	mechanism	NN
cord-350019-4nlbu54e	505	43	of	of	IN
cord-350019-4nlbu54e	505	44	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	505	45	regulation	regulation	NN
cord-350019-4nlbu54e	505	46	by	by	IN
cord-350019-4nlbu54e	505	47	long	long	JJ
cord-350019-4nlbu54e	505	48	non	non	JJ
cord-350019-4nlbu54e	505	49	-	-	JJ
cord-350019-4nlbu54e	505	50	coding	coding	JJ
cord-350019-4nlbu54e	505	51	RNAs	rna	NNS
cord-350019-4nlbu54e	505	52	Evolutionary	evolutionary	JJ
cord-350019-4nlbu54e	505	53	clues	clue	NNS
cord-350019-4nlbu54e	505	54	in	in	IN
cord-350019-4nlbu54e	505	55	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	505	56	Enhancer	Enhancer	NNP
cord-350019-4nlbu54e	505	57	RNAs	rna	NNS
cord-350019-4nlbu54e	505	58	and	and	CC
cord-350019-4nlbu54e	505	59	regulated	regulate	VBN
cord-350019-4nlbu54e	505	60	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	505	61	programs	program	NNS
cord-350019-4nlbu54e	505	62	Long	long	JJ
cord-350019-4nlbu54e	505	63	non	non	JJ
cord-350019-4nlbu54e	505	64	-	-	JJ
cord-350019-4nlbu54e	505	65	coding	coding	JJ
cord-350019-4nlbu54e	505	66	RNAs	rna	NNS
cord-350019-4nlbu54e	505	67	as	as	IN
cord-350019-4nlbu54e	505	68	local	local	JJ
cord-350019-4nlbu54e	505	69	regulators	regulator	NNS
cord-350019-4nlbu54e	505	70	of	of	IN
cord-350019-4nlbu54e	505	71	pancreatic	pancreatic	JJ
cord-350019-4nlbu54e	505	72	islet	islet	NN
cord-350019-4nlbu54e	505	73	transcription	transcription	NN
cord-350019-4nlbu54e	505	74	factor	factor	NN
cord-350019-4nlbu54e	505	75	genes	gene	NNS
cord-350019-4nlbu54e	505	76	Genome	Genome	NNP
cord-350019-4nlbu54e	505	77	-	-	HYPH
cord-350019-4nlbu54e	505	78	wide	wide	JJ
cord-350019-4nlbu54e	505	79	analysis	analysis	NN
cord-350019-4nlbu54e	505	80	of	of	IN
cord-350019-4nlbu54e	505	81	enhancer	enhancer	NNP
cord-350019-4nlbu54e	505	82	RNA	RNA	NNP
cord-350019-4nlbu54e	505	83	in	in	IN
cord-350019-4nlbu54e	505	84	gene	gene	NN
cord-350019-4nlbu54e	505	85	regulation	regulation	NN
cord-350019-4nlbu54e	505	86	across	across	IN
cord-350019-4nlbu54e	505	87	12	12	CD
cord-350019-4nlbu54e	505	88	mouse	mouse	NN
cord-350019-4nlbu54e	505	89	tissues	tissue	VBZ
cord-350019-4nlbu54e	505	90	Expression	expression	NN
cord-350019-4nlbu54e	505	91	of	of	IN
cord-350019-4nlbu54e	505	92	rd29A	rd29a	NN
cord-350019-4nlbu54e	505	93	:	:	:
cord-350019-4nlbu54e	505	94	:	:	:
cord-350019-4nlbu54e	505	95	AtDREB1A/	atdreb1a/	ADD
cord-350019-4nlbu54e	506	1	CBF3	CBF3	NNP
cord-350019-4nlbu54e	506	2	in	in	IN
cord-350019-4nlbu54e	506	3	tomato	tomato	NN
cord-350019-4nlbu54e	506	4	alleviates	alleviate	VBZ
cord-350019-4nlbu54e	506	5	drought	drought	NN
cord-350019-4nlbu54e	506	6	-	-	HYPH
cord-350019-4nlbu54e	506	7	induced	induce	VBN
cord-350019-4nlbu54e	506	8	oxidative	oxidative	JJ
cord-350019-4nlbu54e	506	9	stress	stress	NN
cord-350019-4nlbu54e	506	10	by	by	IN
cord-350019-4nlbu54e	506	11	regulating	regulate	VBG
cord-350019-4nlbu54e	506	12	key	key	JJ
cord-350019-4nlbu54e	506	13	enzymatic	enzymatic	JJ
cord-350019-4nlbu54e	506	14	and	and	CC
cord-350019-4nlbu54e	506	15	non	non	JJ
cord-350019-4nlbu54e	506	16	-	-	JJ
cord-350019-4nlbu54e	506	17	enzymatic	enzymatic	JJ
cord-350019-4nlbu54e	506	18	antioxidants	antioxidant	NNS
cord-350019-4nlbu54e	506	19	ERNAs	erna	NNS
cord-350019-4nlbu54e	506	20	are	be	VBP
cord-350019-4nlbu54e	506	21	required	require	VBN
cord-350019-4nlbu54e	506	22	for	for	IN
cord-350019-4nlbu54e	506	23	p53-dependent	p53-dependent	NN
cord-350019-4nlbu54e	506	24	enhancer	enhancer	NN
cord-350019-4nlbu54e	506	25	activity	activity	NN
cord-350019-4nlbu54e	506	26	and	and	CC
cord-350019-4nlbu54e	506	27	gene	gene	NN
cord-350019-4nlbu54e	506	28	transcription	transcription	NN
cord-350019-4nlbu54e	506	29	Phylogenetic	Phylogenetic	NNP
cord-350019-4nlbu54e	506	30	analysis	analysis	NN
cord-350019-4nlbu54e	506	31	with	with	IN
cord-350019-4nlbu54e	506	32	improved	improved	JJ
cord-350019-4nlbu54e	506	33	parameters	parameter	NNS
cord-350019-4nlbu54e	507	1	reveals	reveal	VBZ
cord-350019-4nlbu54e	507	2	conservation	conservation	NN
cord-350019-4nlbu54e	507	3	in	in	IN
cord-350019-4nlbu54e	507	4	lncRNA	lncrna	NN
cord-350019-4nlbu54e	507	5	structures	structure	NNS
cord-350019-4nlbu54e	507	6	lncRNAdb	lncRNAdb	VBZ
cord-350019-4nlbu54e	507	7	v2.0	v2.0	RB
cord-350019-4nlbu54e	507	8	:	:	:
cord-350019-4nlbu54e	507	9	expanding	expand	VBG
cord-350019-4nlbu54e	507	10	the	the	DT
cord-350019-4nlbu54e	507	11	reference	reference	NN
cord-350019-4nlbu54e	507	12	database	database	NN
cord-350019-4nlbu54e	507	13	for	for	IN
cord-350019-4nlbu54e	507	14	functional	functional	JJ
cord-350019-4nlbu54e	507	15	long	long	JJ
cord-350019-4nlbu54e	507	16	noncoding	noncoding	JJ
cord-350019-4nlbu54e	507	17	RNAs	rna	NNS
cord-350019-4nlbu54e	508	1	The	the	DT
cord-350019-4nlbu54e	508	2	UCSC	UCSC	NNP
cord-350019-4nlbu54e	508	3	genome	genome	NN
cord-350019-4nlbu54e	508	4	browser	browser	NN
cord-350019-4nlbu54e	509	1	A	a	DT
cord-350019-4nlbu54e	509	2	long	long	JJ
cord-350019-4nlbu54e	509	3	noncoding	noncoding	JJ
cord-350019-4nlbu54e	509	4	RNA	RNA	NNP
cord-350019-4nlbu54e	509	5	,	,	,
cord-350019-4nlbu54e	509	6	lincRNA	lincRNA	NNP
cord-350019-4nlbu54e	509	7	-	-	HYPH
cord-350019-4nlbu54e	509	8	Tnfaip3	Tnfaip3	NNP
cord-350019-4nlbu54e	509	9	,	,	,
cord-350019-4nlbu54e	509	10	acts	act	VBZ
cord-350019-4nlbu54e	509	11	as	as	IN
cord-350019-4nlbu54e	509	12	a	a	DT
cord-350019-4nlbu54e	509	13	coregulator	coregulator	NN
cord-350019-4nlbu54e	509	14	of	of	IN
cord-350019-4nlbu54e	509	15	NF	NF	NNP
cord-350019-4nlbu54e	509	16	-	-	HYPH
cord-350019-4nlbu54e	509	17	κB	κB	NNP
cord-350019-4nlbu54e	509	18	to	to	TO
cord-350019-4nlbu54e	509	19	modulate	modulate	VB
cord-350019-4nlbu54e	509	20	inflammatory	inflammatory	JJ
cord-350019-4nlbu54e	509	21	gene	gene	NN
cord-350019-4nlbu54e	509	22	transcription	transcription	NN
cord-350019-4nlbu54e	509	23	in	in	IN
cord-350019-4nlbu54e	509	24	mouse	mouse	NN
cord-350019-4nlbu54e	509	25	macrophages	macrophage	NNS
cord-350019-4nlbu54e	509	26	p50-associated	p50-associated	CD
cord-350019-4nlbu54e	510	1	COX-2	COX-2	NNP
cord-350019-4nlbu54e	510	2	extragenic	extragenic	NNP
cord-350019-4nlbu54e	510	3	RNA	RNA	NNP
cord-350019-4nlbu54e	510	4	(	(	-LRB-
cord-350019-4nlbu54e	510	5	PACER	PACER	NNP
cord-350019-4nlbu54e	510	6	)	)	-RRB-
cord-350019-4nlbu54e	510	7	activates	activate	VBZ
cord-350019-4nlbu54e	510	8	COX-2	cox-2	JJ
cord-350019-4nlbu54e	510	9	gene	gene	NN
cord-350019-4nlbu54e	510	10	expression	expression	NN
cord-350019-4nlbu54e	510	11	by	by	IN
cord-350019-4nlbu54e	510	12	occluding	occlude	VBG
cord-350019-4nlbu54e	510	13	repressive	repressive	JJ
cord-350019-4nlbu54e	510	14	NF	nf	NN
cord-350019-4nlbu54e	510	15	-	-	HYPH
cord-350019-4nlbu54e	510	16	κB	κB	NNP
cord-350019-4nlbu54e	510	17	complexes	complex	NNS
cord-350019-4nlbu54e	510	18	Genome	genome	NN
cord-350019-4nlbu54e	510	19	-	-	HYPH
cord-350019-4nlbu54e	510	20	wide	wide	JJ
cord-350019-4nlbu54e	510	21	mapping	mapping	NN
cord-350019-4nlbu54e	510	22	of	of	IN
cord-350019-4nlbu54e	510	23	DNase	DNase	NNP
cord-350019-4nlbu54e	510	24	hypersensitive	hypersensitive	JJ
cord-350019-4nlbu54e	510	25	sites	site	NNS
cord-350019-4nlbu54e	510	26	using	use	VBG
cord-350019-4nlbu54e	510	27	massively	massively	RB
cord-350019-4nlbu54e	510	28	parallel	parallel	JJ
cord-350019-4nlbu54e	510	29	signature	signature	NN
cord-350019-4nlbu54e	510	30	sequencing	sequencing	NN
cord-350019-4nlbu54e	510	31	(	(	-LRB-
cord-350019-4nlbu54e	510	32	MPSS	MPSS	NNP
cord-350019-4nlbu54e	510	33	)	)	-RRB-
cord-350019-4nlbu54e	510	34	ATAC	ATAC	NNP
cord-350019-4nlbu54e	510	35	-	-	HYPH
cord-350019-4nlbu54e	510	36	seq	seq	NNP
cord-350019-4nlbu54e	510	37	:	:	:
cord-350019-4nlbu54e	510	38	a	a	DT
cord-350019-4nlbu54e	510	39	method	method	NN
cord-350019-4nlbu54e	510	40	for	for	IN
cord-350019-4nlbu54e	510	41	assaying	assay	VBG
cord-350019-4nlbu54e	510	42	chromatin	chromatin	NN
cord-350019-4nlbu54e	510	43	accessibility	accessibility	NN
cord-350019-4nlbu54e	510	44	genome	genome	NN
cord-350019-4nlbu54e	510	45	-	-	:
cord-350019-4nlbu54e	510	46	wide	wide	JJ
cord-350019-4nlbu54e	510	47	The	the	DT
cord-350019-4nlbu54e	510	48	tale	tale	NN
cord-350019-4nlbu54e	510	49	of	of	IN
cord-350019-4nlbu54e	510	50	histone	histone	NN
cord-350019-4nlbu54e	510	51	modifications	modification	NNS
cord-350019-4nlbu54e	510	52	and	and	CC
cord-350019-4nlbu54e	510	53	its	-PRON-	PRP$
cord-350019-4nlbu54e	510	54	role	role	NN
cord-350019-4nlbu54e	510	55	in	in	IN
cord-350019-4nlbu54e	510	56	multiple	multiple	JJ
cord-350019-4nlbu54e	510	57	sclerosis	sclerosis	NN
cord-350019-4nlbu54e	511	1	The	the	DT
cord-350019-4nlbu54e	511	2	histone	histone	NN
cord-350019-4nlbu54e	511	3	modification	modification	NN
cord-350019-4nlbu54e	511	4	code	code	NN
cord-350019-4nlbu54e	511	5	in	in	IN
cord-350019-4nlbu54e	511	6	the	the	DT
cord-350019-4nlbu54e	511	7	pathogenesis	pathogenesis	NN
cord-350019-4nlbu54e	511	8	of	of	IN
cord-350019-4nlbu54e	511	9	autoimmune	autoimmune	JJ
cord-350019-4nlbu54e	511	10	diseases	disease	NNS
cord-350019-4nlbu54e	512	1	Histone	histone	JJ
cord-350019-4nlbu54e	512	2	modifications	modification	NNS
cord-350019-4nlbu54e	512	3	and	and	CC
cord-350019-4nlbu54e	512	4	their	-PRON-	PRP$
cord-350019-4nlbu54e	512	5	role	role	NN
cord-350019-4nlbu54e	512	6	in	in	IN
cord-350019-4nlbu54e	512	7	epigenetics	epigenetic	NNS
cord-350019-4nlbu54e	512	8	of	of	IN
cord-350019-4nlbu54e	512	9	atopy	atopy	NN
cord-350019-4nlbu54e	512	10	and	and	CC
cord-350019-4nlbu54e	512	11	allergic	allergic	JJ
cord-350019-4nlbu54e	512	12	diseases	disease	NNS
cord-350019-4nlbu54e	512	13	Regulation	regulation	NN
cord-350019-4nlbu54e	512	14	of	of	IN
cord-350019-4nlbu54e	512	15	chromatin	chromatin	NN
cord-350019-4nlbu54e	512	16	by	by	IN
cord-350019-4nlbu54e	512	17	histone	histone	NN
cord-350019-4nlbu54e	512	18	modifications	modification	NNS
cord-350019-4nlbu54e	513	1	Acetylation	acetylation	NN
cord-350019-4nlbu54e	513	2	and	and	CC
cord-350019-4nlbu54e	513	3	methylation	methylation	NN
cord-350019-4nlbu54e	513	4	of	of	IN
cord-350019-4nlbu54e	513	5	histones	histone	NNS
cord-350019-4nlbu54e	513	6	and	and	CC
cord-350019-4nlbu54e	513	7	their	-PRON-	PRP$
cord-350019-4nlbu54e	513	8	possible	possible	JJ
cord-350019-4nlbu54e	513	9	role	role	NN
cord-350019-4nlbu54e	513	10	in	in	IN
cord-350019-4nlbu54e	513	11	the	the	DT
cord-350019-4nlbu54e	513	12	regulation	regulation	NN
cord-350019-4nlbu54e	513	13	of	of	IN
cord-350019-4nlbu54e	513	14	RNA	RNA	NNP
cord-350019-4nlbu54e	513	15	synthesis	synthesis	NN
cord-350019-4nlbu54e	513	16	Regulatory	regulatory	JJ
cord-350019-4nlbu54e	513	17	networks	network	NNS
cord-350019-4nlbu54e	513	18	involving	involve	VBG
cord-350019-4nlbu54e	513	19	STATs	STATs	NNP
cord-350019-4nlbu54e	513	20	,	,	,
cord-350019-4nlbu54e	513	21	IRFs	irfs	NN
cord-350019-4nlbu54e	513	22	,	,	,
cord-350019-4nlbu54e	513	23	and	and	CC
cord-350019-4nlbu54e	513	24	NFκB	NFκB	NNP
cord-350019-4nlbu54e	513	25	in	in	IN
cord-350019-4nlbu54e	513	26	inflammation	inflammation	NN
cord-350019-4nlbu54e	513	27	Single	single	JJ
cord-350019-4nlbu54e	513	28	-	-	HYPH
cord-350019-4nlbu54e	513	29	cell	cell	NN
cord-350019-4nlbu54e	513	30	proteomics	proteomic	NNS
cord-350019-4nlbu54e	513	31	reveal	reveal	VBP
cord-350019-4nlbu54e	513	32	that	that	IN
cord-350019-4nlbu54e	513	33	quantitative	quantitative	JJ
cord-350019-4nlbu54e	513	34	changes	change	NNS
cord-350019-4nlbu54e	513	35	in	in	IN
cord-350019-4nlbu54e	513	36	coexpressed	coexpresse	VBN
cord-350019-4nlbu54e	513	37	lineage	lineage	NN
cord-350019-4nlbu54e	513	38	-	-	HYPH
cord-350019-4nlbu54e	513	39	specific	specific	JJ
cord-350019-4nlbu54e	513	40	transcription	transcription	NN
cord-350019-4nlbu54e	513	41	factors	factor	NNS
cord-350019-4nlbu54e	513	42	determine	determine	VBP
cord-350019-4nlbu54e	513	43	cell	cell	NN
cord-350019-4nlbu54e	513	44	fate	fate	NN
cord-350019-4nlbu54e	513	45	Post	post	JJ
cord-350019-4nlbu54e	513	46	-	-	JJ
cord-350019-4nlbu54e	513	47	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	513	48	regulation	regulation	NN
cord-350019-4nlbu54e	513	49	of	of	IN
cord-350019-4nlbu54e	513	50	gene	gene	NN
cord-350019-4nlbu54e	513	51	expression	expression	NN
cord-350019-4nlbu54e	513	52	in	in	IN
cord-350019-4nlbu54e	513	53	innate	innate	JJ
cord-350019-4nlbu54e	513	54	immunity	immunity	NN
cord-350019-4nlbu54e	514	1	An	an	DT
cord-350019-4nlbu54e	514	2	enhanced	enhanced	JJ
cord-350019-4nlbu54e	514	3	computational	computational	JJ
cord-350019-4nlbu54e	514	4	platform	platform	NN
cord-350019-4nlbu54e	514	5	for	for	IN
cord-350019-4nlbu54e	514	6	investigating	investigate	VBG
cord-350019-4nlbu54e	514	7	the	the	DT
cord-350019-4nlbu54e	514	8	roles	role	NNS
cord-350019-4nlbu54e	514	9	of	of	IN
cord-350019-4nlbu54e	514	10	regulatory	regulatory	JJ
cord-350019-4nlbu54e	514	11	RNA	RNA	NNP
cord-350019-4nlbu54e	514	12	and	and	CC
cord-350019-4nlbu54e	514	13	for	for	IN
cord-350019-4nlbu54e	514	14	identifying	identify	VBG
cord-350019-4nlbu54e	514	15	functional	functional	JJ
cord-350019-4nlbu54e	514	16	RNA	RNA	NNP
cord-350019-4nlbu54e	514	17	motifs	motif	NNS
cord-350019-4nlbu54e	514	18	Analysis	Analysis	NNP
cord-350019-4nlbu54e	514	19	of	of	IN
cord-350019-4nlbu54e	514	20	genomic	genomic	JJ
cord-350019-4nlbu54e	514	21	sequence	sequence	NN
cord-350019-4nlbu54e	514	22	motifs	motif	NNS
cord-350019-4nlbu54e	514	23	for	for	IN
cord-350019-4nlbu54e	514	24	deciphering	decipher	VBG
cord-350019-4nlbu54e	514	25	transcription	transcription	NN
cord-350019-4nlbu54e	514	26	factor	factor	NN
cord-350019-4nlbu54e	514	27	binding	binding	NN
cord-350019-4nlbu54e	514	28	and	and	CC
cord-350019-4nlbu54e	514	29	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	514	30	regulation	regulation	NN
cord-350019-4nlbu54e	514	31	in	in	IN
cord-350019-4nlbu54e	514	32	eukaryotic	eukaryotic	JJ
cord-350019-4nlbu54e	514	33	cells	cell	NNS
cord-350019-4nlbu54e	514	34	Simple	simple	JJ
cord-350019-4nlbu54e	514	35	combinations	combination	NNS
cord-350019-4nlbu54e	514	36	of	of	IN
cord-350019-4nlbu54e	514	37	lineage	lineage	NN
cord-350019-4nlbu54e	514	38	-	-	HYPH
cord-350019-4nlbu54e	514	39	determining	determine	VBG
cord-350019-4nlbu54e	514	40	transcription	transcription	NN
cord-350019-4nlbu54e	514	41	factors	factor	NNS
cord-350019-4nlbu54e	514	42	prime	prime	NNP
cord-350019-4nlbu54e	514	43	cis	cis	JJ
cord-350019-4nlbu54e	514	44	-	-	HYPH
cord-350019-4nlbu54e	514	45	regulatory	regulatory	JJ
cord-350019-4nlbu54e	514	46	elements	element	NNS
cord-350019-4nlbu54e	514	47	required	require	VBN
cord-350019-4nlbu54e	514	48	for	for	IN
cord-350019-4nlbu54e	514	49	macrophage	macrophage	NN
cord-350019-4nlbu54e	514	50	and	and	CC
cord-350019-4nlbu54e	514	51	B	b	NN
cord-350019-4nlbu54e	514	52	cell	cell	NN
cord-350019-4nlbu54e	514	53	identities	identity	NNS
cord-350019-4nlbu54e	514	54	Discrimination	discrimination	NN
cord-350019-4nlbu54e	514	55	of	of	IN
cord-350019-4nlbu54e	514	56	non	non	JJ
cord-350019-4nlbu54e	514	57	-	-	JJ
cord-350019-4nlbu54e	514	58	protein	protein	JJ
cord-350019-4nlbu54e	514	59	-	-	HYPH
cord-350019-4nlbu54e	514	60	coding	code	VBG
cord-350019-4nlbu54e	514	61	transcripts	transcript	NNS
cord-350019-4nlbu54e	514	62	from	from	IN
cord-350019-4nlbu54e	514	63	proteincoding	proteincode	VBG
cord-350019-4nlbu54e	514	64	mRNA	mRNA	NNP
cord-350019-4nlbu54e	514	65	Peptides	peptide	NNS
cord-350019-4nlbu54e	514	66	encoded	encode	VBN
cord-350019-4nlbu54e	514	67	by	by	IN
cord-350019-4nlbu54e	514	68	short	short	JJ
cord-350019-4nlbu54e	514	69	ORFs	ORFs	NNP
cord-350019-4nlbu54e	514	70	control	control	NN
cord-350019-4nlbu54e	514	71	development	development	NN
cord-350019-4nlbu54e	514	72	and	and	CC
cord-350019-4nlbu54e	514	73	define	define	VB
cord-350019-4nlbu54e	514	74	a	a	DT
cord-350019-4nlbu54e	514	75	new	new	JJ
cord-350019-4nlbu54e	514	76	eukaryotic	eukaryotic	JJ
cord-350019-4nlbu54e	514	77	gene	gene	NN
cord-350019-4nlbu54e	514	78	family	family	NN
cord-350019-4nlbu54e	514	79	Small	small	JJ
cord-350019-4nlbu54e	514	80	open	open	JJ
cord-350019-4nlbu54e	514	81	reading	reading	NN
cord-350019-4nlbu54e	514	82	frames	frame	NNS
cord-350019-4nlbu54e	514	83	:	:	:
cord-350019-4nlbu54e	514	84	current	current	JJ
cord-350019-4nlbu54e	514	85	prediction	prediction	NN
cord-350019-4nlbu54e	514	86	techniques	technique	NNS
cord-350019-4nlbu54e	514	87	and	and	CC
cord-350019-4nlbu54e	514	88	future	future	JJ
cord-350019-4nlbu54e	514	89	prospect	prospect	NN
cord-350019-4nlbu54e	515	1	Peptidomic	Peptidomic	NNP
cord-350019-4nlbu54e	515	2	discovery	discovery	NN
cord-350019-4nlbu54e	515	3	of	of	IN
cord-350019-4nlbu54e	515	4	short	short	JJ
cord-350019-4nlbu54e	515	5	open	open	JJ
cord-350019-4nlbu54e	515	6	reading	reading	NN
cord-350019-4nlbu54e	515	7	frame	frame	NN
cord-350019-4nlbu54e	515	8	-	-	HYPH
cord-350019-4nlbu54e	515	9	encoded	encode	VBN
cord-350019-4nlbu54e	515	10	peptides	peptide	NNS
cord-350019-4nlbu54e	515	11	in	in	IN
cord-350019-4nlbu54e	515	12	human	human	JJ
cord-350019-4nlbu54e	515	13	cells	cell	NNS
cord-350019-4nlbu54e	515	14	Ribosome	Ribosome	NNP
cord-350019-4nlbu54e	515	15	profiling	profiling	NN
cord-350019-4nlbu54e	515	16	reveals	reveal	VBZ
cord-350019-4nlbu54e	515	17	pervasive	pervasive	JJ
cord-350019-4nlbu54e	515	18	translation	translation	NN
cord-350019-4nlbu54e	515	19	outside	outside	RB
cord-350019-4nlbu54e	515	20	of	of	IN
cord-350019-4nlbu54e	515	21	annotated	annotated	JJ
cord-350019-4nlbu54e	515	22	protein	protein	NN
cord-350019-4nlbu54e	515	23	-	-	HYPH
cord-350019-4nlbu54e	515	24	coding	code	VBG
cord-350019-4nlbu54e	515	25	genes	gene	NNS
cord-350019-4nlbu54e	516	1	Genomewide	Genomewide	NNP
cord-350019-4nlbu54e	516	2	analysis	analysis	NN
cord-350019-4nlbu54e	516	3	in	in	IN
cord-350019-4nlbu54e	516	4	vivo	vivo	NN
cord-350019-4nlbu54e	516	5	of	of	IN
cord-350019-4nlbu54e	516	6	translation	translation	NN
cord-350019-4nlbu54e	516	7	with	with	IN
cord-350019-4nlbu54e	516	8	nucleotide	nucleotide	JJ
cord-350019-4nlbu54e	516	9	resolution	resolution	NN
cord-350019-4nlbu54e	516	10	using	use	VBG
cord-350019-4nlbu54e	516	11	ribosome	ribosome	NN
cord-350019-4nlbu54e	516	12	profiling	profile	VBG
cord-350019-4nlbu54e	516	13	Ribosome	Ribosome	NNP
cord-350019-4nlbu54e	516	14	profiling	profiling	NN
cord-350019-4nlbu54e	516	15	provides	provide	VBZ
cord-350019-4nlbu54e	516	16	evidence	evidence	NN
cord-350019-4nlbu54e	516	17	that	that	IN
cord-350019-4nlbu54e	516	18	large	large	JJ
cord-350019-4nlbu54e	516	19	noncoding	noncoding	JJ
cord-350019-4nlbu54e	516	20	RNAs	rna	NNS
cord-350019-4nlbu54e	516	21	do	do	VBP
cord-350019-4nlbu54e	516	22	not	not	RB
cord-350019-4nlbu54e	516	23	encode	encode	VB
cord-350019-4nlbu54e	516	24	proteins	protein	NNS
cord-350019-4nlbu54e	516	25	Cytoplasmic	Cytoplasmic	NNP
cord-350019-4nlbu54e	516	26	long	long	RB
cord-350019-4nlbu54e	516	27	noncoding	noncoding	JJ
cord-350019-4nlbu54e	516	28	RNAs	rna	NNS
cord-350019-4nlbu54e	516	29	are	be	VBP
cord-350019-4nlbu54e	516	30	frequently	frequently	RB
cord-350019-4nlbu54e	516	31	bound	bind	VBN
cord-350019-4nlbu54e	516	32	to	to	IN
cord-350019-4nlbu54e	516	33	and	and	CC
cord-350019-4nlbu54e	516	34	degraded	degrade	VBN
cord-350019-4nlbu54e	516	35	at	at	IN
cord-350019-4nlbu54e	516	36	ribosomes	ribosome	NNS
cord-350019-4nlbu54e	516	37	in	in	IN
cord-350019-4nlbu54e	516	38	human	human	JJ
cord-350019-4nlbu54e	516	39	cells	cell	NNS
cord-350019-4nlbu54e	516	40	Ribosome	Ribosome	NNP
cord-350019-4nlbu54e	516	41	profiling	profiling	NN
cord-350019-4nlbu54e	516	42	reveals	reveal	VBZ
cord-350019-4nlbu54e	516	43	resemblance	resemblance	NN
cord-350019-4nlbu54e	516	44	between	between	IN
cord-350019-4nlbu54e	516	45	long	long	JJ
cord-350019-4nlbu54e	516	46	non	non	JJ
cord-350019-4nlbu54e	516	47	-	-	JJ
cord-350019-4nlbu54e	516	48	coding	coding	JJ
cord-350019-4nlbu54e	516	49	RNAs	rna	NNS
cord-350019-4nlbu54e	516	50	and	and	CC
cord-350019-4nlbu54e	516	51	5′	5′	CD
cord-350019-4nlbu54e	516	52	leaders	leader	NNS
cord-350019-4nlbu54e	516	53	of	of	IN
cord-350019-4nlbu54e	516	54	coding	code	VBG
cord-350019-4nlbu54e	516	55	RNAs	rna	NNS
cord-350019-4nlbu54e	517	1	The	the	DT
cord-350019-4nlbu54e	517	2	translation	translation	NN
cord-350019-4nlbu54e	517	3	of	of	IN
cord-350019-4nlbu54e	517	4	non	non	JJ
cord-350019-4nlbu54e	517	5	-	-	JJ
cord-350019-4nlbu54e	517	6	canonical	canonical	JJ
cord-350019-4nlbu54e	517	7	open	open	JJ
cord-350019-4nlbu54e	517	8	reading	reading	NN
cord-350019-4nlbu54e	517	9	frames	frame	NNS
cord-350019-4nlbu54e	517	10	controls	control	NNS
cord-350019-4nlbu54e	517	11	mucosal	mucosal	JJ
cord-350019-4nlbu54e	517	12	immunity	immunity	NN
cord-350019-4nlbu54e	517	13	Lncbook	Lncbook	NNP
cord-350019-4nlbu54e	517	14	:	:	:
cord-350019-4nlbu54e	517	15	a	a	DT
cord-350019-4nlbu54e	517	16	curated	curate	VBN
cord-350019-4nlbu54e	517	17	knowledgebase	knowledgebase	NN
cord-350019-4nlbu54e	517	18	of	of	IN
cord-350019-4nlbu54e	517	19	human	human	JJ
cord-350019-4nlbu54e	517	20	long	long	JJ
cord-350019-4nlbu54e	517	21	non	non	JJ
cord-350019-4nlbu54e	517	22	-	-	JJ
cord-350019-4nlbu54e	517	23	coding	coding	JJ
cord-350019-4nlbu54e	517	24	rnas	rna	NNS
cord-350019-4nlbu54e	517	25	Choosing	choose	VBG
cord-350019-4nlbu54e	517	26	the	the	DT
cord-350019-4nlbu54e	517	27	right	right	JJ
cord-350019-4nlbu54e	517	28	tool	tool	NN
cord-350019-4nlbu54e	517	29	for	for	IN
cord-350019-4nlbu54e	517	30	the	the	DT
cord-350019-4nlbu54e	517	31	job	job	NN
cord-350019-4nlbu54e	517	32	RNA	RNA	NNP
cord-350019-4nlbu54e	517	33	interference	interference	NN
cord-350019-4nlbu54e	517	34	:	:	:
cord-350019-4nlbu54e	517	35	from	from	IN
cord-350019-4nlbu54e	517	36	basic	basic	JJ
cord-350019-4nlbu54e	517	37	research	research	NN
cord-350019-4nlbu54e	517	38	to	to	IN
cord-350019-4nlbu54e	517	39	therapeutic	therapeutic	JJ
cord-350019-4nlbu54e	517	40	applications	application	NNS
cord-350019-4nlbu54e	517	41	Short	short	JJ
cord-350019-4nlbu54e	517	42	hairpin	hairpin	NN
cord-350019-4nlbu54e	517	43	RNA	rna	NN
cord-350019-4nlbu54e	517	44	-	-	HYPH
cord-350019-4nlbu54e	517	45	mediated	mediate	VBN
cord-350019-4nlbu54e	517	46	gene	gene	NN
cord-350019-4nlbu54e	517	47	silencing	silence	VBG
cord-350019-4nlbu54e	517	48	Cellular	cellular	JJ
cord-350019-4nlbu54e	517	49	localization	localization	NN
cord-350019-4nlbu54e	517	50	of	of	IN
cord-350019-4nlbu54e	517	51	long	long	JJ
cord-350019-4nlbu54e	517	52	non	non	JJ
cord-350019-4nlbu54e	517	53	-	-	JJ
cord-350019-4nlbu54e	517	54	coding	coding	JJ
cord-350019-4nlbu54e	517	55	RNAs	rna	NNS
cord-350019-4nlbu54e	517	56	affects	affect	VBZ
cord-350019-4nlbu54e	517	57	silencing	silence	VBG
cord-350019-4nlbu54e	517	58	by	by	IN
cord-350019-4nlbu54e	517	59	RNAi	RNAi	NNS
cord-350019-4nlbu54e	517	60	more	more	JJR
cord-350019-4nlbu54e	517	61	than	than	IN
cord-350019-4nlbu54e	517	62	by	by	IN
cord-350019-4nlbu54e	517	63	antisense	antisense	NN
cord-350019-4nlbu54e	517	64	oligonucleotides	oligonucleotide	NNS
cord-350019-4nlbu54e	518	1	Knockdown	knockdown	NN
cord-350019-4nlbu54e	518	2	of	of	IN
cord-350019-4nlbu54e	518	3	nuclear	nuclear	NN
cord-350019-4nlbu54e	518	4	-	-	HYPH
cord-350019-4nlbu54e	518	5	retained	retain	VBN
cord-350019-4nlbu54e	518	6	long	long	JJ
cord-350019-4nlbu54e	518	7	noncoding	noncoding	JJ
cord-350019-4nlbu54e	518	8	RNAs	rna	NNS
cord-350019-4nlbu54e	518	9	using	use	VBG
cord-350019-4nlbu54e	518	10	modified	modify	VBN
cord-350019-4nlbu54e	518	11	DNA	dna	NN
cord-350019-4nlbu54e	518	12	antisense	antisense	NN
cord-350019-4nlbu54e	518	13	oligonucleotides	oligonucleotide	NNS
cord-350019-4nlbu54e	518	14	Designing	design	VBG
cord-350019-4nlbu54e	518	15	chemically	chemically	RB
cord-350019-4nlbu54e	518	16	modified	modify	VBN
cord-350019-4nlbu54e	518	17	oligonucleotides	oligonucleotide	NNS
cord-350019-4nlbu54e	518	18	for	for	IN
cord-350019-4nlbu54e	518	19	targeted	target	VBN
cord-350019-4nlbu54e	518	20	gene	gene	NN
cord-350019-4nlbu54e	518	21	silencing	silence	VBG
cord-350019-4nlbu54e	518	22	Ribonuclease	Ribonuclease	NNP
cord-350019-4nlbu54e	518	23	H	H	NNP
cord-350019-4nlbu54e	518	24	:	:	:
cord-350019-4nlbu54e	518	25	the	the	DT
cord-350019-4nlbu54e	518	26	enzymes	enzyme	NNS
cord-350019-4nlbu54e	518	27	in	in	IN
cord-350019-4nlbu54e	518	28	eukaryotes	eukaryote	NNS
cord-350019-4nlbu54e	518	29	Fatty	fatty	JJ
cord-350019-4nlbu54e	518	30	acid	acid	NN
cord-350019-4nlbu54e	518	31	-	-	HYPH
cord-350019-4nlbu54e	518	32	modified	modify	VBN
cord-350019-4nlbu54e	518	33	gapmer	gapmer	NN
cord-350019-4nlbu54e	518	34	antisense	antisense	NNP
cord-350019-4nlbu54e	518	35	oligonucleotide	oligonucleotide	NNP
cord-350019-4nlbu54e	518	36	and	and	CC
cord-350019-4nlbu54e	518	37	serum	serum	NN
cord-350019-4nlbu54e	518	38	albumin	albumin	NN
cord-350019-4nlbu54e	518	39	constructs	construct	NNS
cord-350019-4nlbu54e	518	40	for	for	IN
cord-350019-4nlbu54e	518	41	pharmacokinetic	pharmacokinetic	JJ
cord-350019-4nlbu54e	518	42	modulation	modulation	NN
cord-350019-4nlbu54e	518	43	Angelman	Angelman	NNP
cord-350019-4nlbu54e	518	44	syndrome	syndrome	NN
cord-350019-4nlbu54e	518	45	,	,	,
cord-350019-4nlbu54e	518	46	Heal	heal	VB
cord-350019-4nlbu54e	518	47	.	.	.
cord-350019-4nlbu54e	519	1	Care	care	VB
cord-350019-4nlbu54e	519	2	People	People	NNS
cord-350019-4nlbu54e	519	3	with	with	IN
cord-350019-4nlbu54e	519	4	Intellect	Intellect	NNP
cord-350019-4nlbu54e	519	5	Towards	towards	IN
cord-350019-4nlbu54e	519	6	a	a	DT
cord-350019-4nlbu54e	519	7	therapy	therapy	NN
cord-350019-4nlbu54e	519	8	for	for	IN
cord-350019-4nlbu54e	519	9	Angelman	Angelman	NNP
cord-350019-4nlbu54e	519	10	syndrome	syndrome	NN
cord-350019-4nlbu54e	519	11	by	by	IN
cord-350019-4nlbu54e	519	12	targeting	target	VBG
cord-350019-4nlbu54e	519	13	a	a	DT
cord-350019-4nlbu54e	519	14	long	long	JJ
cord-350019-4nlbu54e	519	15	non	non	JJ
cord-350019-4nlbu54e	519	16	-	-	JJ
cord-350019-4nlbu54e	519	17	coding	coding	JJ
cord-350019-4nlbu54e	519	18	RNA	RNA	NNP
cord-350019-4nlbu54e	519	19	RNA	RNA	NNP
cord-350019-4nlbu54e	519	20	interference	interference	NN
cord-350019-4nlbu54e	519	21	-	-	HYPH
cord-350019-4nlbu54e	519	22	significance	significance	NN
cord-350019-4nlbu54e	519	23	and	and	CC
cord-350019-4nlbu54e	519	24	applications	application	NNS
cord-350019-4nlbu54e	519	25	Molecular	molecular	JJ
cord-350019-4nlbu54e	519	26	mechanisms	mechanism	NNS
cord-350019-4nlbu54e	519	27	of	of	IN
cord-350019-4nlbu54e	519	28	antisense	antisense	NN
cord-350019-4nlbu54e	519	29	oligonucleotides	oligonucleotide	NNS
cord-350019-4nlbu54e	519	30	,	,	,
cord-350019-4nlbu54e	520	1	Nucleic	nucleic	JJ
cord-350019-4nlbu54e	520	2	Acid	acid	NN
cord-350019-4nlbu54e	520	3	Ther	Ther	NNP
cord-350019-4nlbu54e	520	4	RNA	RNA	NNP
cord-350019-4nlbu54e	520	5	interference	interference	NN
cord-350019-4nlbu54e	520	6	in	in	IN
cord-350019-4nlbu54e	520	7	the	the	DT
cord-350019-4nlbu54e	520	8	nucleus	nucleus	NN
cord-350019-4nlbu54e	520	9	:	:	:
cord-350019-4nlbu54e	520	10	roles	role	NNS
cord-350019-4nlbu54e	520	11	for	for	IN
cord-350019-4nlbu54e	520	12	small	small	JJ
cord-350019-4nlbu54e	520	13	RNAs	rna	NNS
cord-350019-4nlbu54e	520	14	in	in	IN
cord-350019-4nlbu54e	520	15	transcription	transcription	NN
cord-350019-4nlbu54e	520	16	,	,	,
cord-350019-4nlbu54e	520	17	epigenetics	epigenetic	NNS
cord-350019-4nlbu54e	520	18	and	and	CC
cord-350019-4nlbu54e	520	19	beyond	beyond	IN
cord-350019-4nlbu54e	520	20	Transcriptional	Transcriptional	NNP
cord-350019-4nlbu54e	520	21	termination	termination	NN
cord-350019-4nlbu54e	520	22	in	in	IN
cord-350019-4nlbu54e	520	23	mammals	mammal	NNS
cord-350019-4nlbu54e	520	24	:	:	:
cord-350019-4nlbu54e	521	1	stopping	stop	VBG
cord-350019-4nlbu54e	521	2	the	the	DT
cord-350019-4nlbu54e	521	3	RNA	RNA	NNP
cord-350019-4nlbu54e	521	4	polymerase	polymerase	NN
cord-350019-4nlbu54e	521	5	juggernaut	juggernaut	NN
cord-350019-4nlbu54e	521	6	,	,	,
cord-350019-4nlbu54e	521	7	Science	Science	NNP
cord-350019-4nlbu54e	521	8	(	(	-LRB-
cord-350019-4nlbu54e	521	9	80-	80-	CD
cord-350019-4nlbu54e	521	10	.	.	.
cord-350019-4nlbu54e	521	11	)	)	-RRB-
cord-350019-4nlbu54e	522	1	Dicer	dicer	NN
cord-350019-4nlbu54e	522	2	promotes	promote	VBZ
cord-350019-4nlbu54e	522	3	transcription	transcription	NN
cord-350019-4nlbu54e	522	4	termination	termination	NN
cord-350019-4nlbu54e	522	5	at	at	IN
cord-350019-4nlbu54e	522	6	sites	site	NNS
cord-350019-4nlbu54e	522	7	of	of	IN
cord-350019-4nlbu54e	522	8	replication	replication	NN
cord-350019-4nlbu54e	522	9	stress	stress	NN
cord-350019-4nlbu54e	522	10	to	to	TO
cord-350019-4nlbu54e	522	11	maintain	maintain	VB
cord-350019-4nlbu54e	522	12	genome	genome	NN
cord-350019-4nlbu54e	522	13	stability	stability	NN
cord-350019-4nlbu54e	522	14	Cutting	cut	VBG
cord-350019-4nlbu54e	522	15	it	-PRON-	PRP
cord-350019-4nlbu54e	522	16	close	close	RB
cord-350019-4nlbu54e	522	17	:	:	:
cord-350019-4nlbu54e	522	18	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	522	19	-	-	HYPH
cord-350019-4nlbu54e	522	20	associated	associate	VBN
cord-350019-4nlbu54e	522	21	endoribonuclease	endoribonuclease	NN
cord-350019-4nlbu54e	522	22	structure	structure	NN
cord-350019-4nlbu54e	522	23	and	and	CC
cord-350019-4nlbu54e	522	24	function	function	NN
cord-350019-4nlbu54e	523	1	Expanding	expand	VBG
cord-350019-4nlbu54e	523	2	the	the	DT
cord-350019-4nlbu54e	523	3	Biologist	Biologist	NNP
cord-350019-4nlbu54e	523	4	's	's	POS
cord-350019-4nlbu54e	523	5	toolkit	toolkit	NN
cord-350019-4nlbu54e	523	6	with	with	IN
cord-350019-4nlbu54e	524	1	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	524	2	-	-	HYPH
cord-350019-4nlbu54e	524	3	Cas9	Cas9	NNP
cord-350019-4nlbu54e	524	4	Targeting	target	VBG
cord-350019-4nlbu54e	524	5	non	non	JJ
cord-350019-4nlbu54e	524	6	-	-	JJ
cord-350019-4nlbu54e	524	7	coding	coding	JJ
cord-350019-4nlbu54e	524	8	RNAs	rna	NNS
cord-350019-4nlbu54e	524	9	with	with	IN
cord-350019-4nlbu54e	524	10	the	the	DT
cord-350019-4nlbu54e	524	11	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	524	12	/	/	SYM
cord-350019-4nlbu54e	524	13	Cas9	Cas9	NNP
cord-350019-4nlbu54e	524	14	system	system	NN
cord-350019-4nlbu54e	524	15	in	in	IN
cord-350019-4nlbu54e	524	16	human	human	JJ
cord-350019-4nlbu54e	524	17	cell	cell	NN
cord-350019-4nlbu54e	524	18	lines	line	NNS
cord-350019-4nlbu54e	524	19	Genome	Genome	NNP
cord-350019-4nlbu54e	524	20	-	-	HYPH
cord-350019-4nlbu54e	524	21	scale	scale	NN
cord-350019-4nlbu54e	524	22	deletion	deletion	NN
cord-350019-4nlbu54e	524	23	screening	screening	NN
cord-350019-4nlbu54e	524	24	of	of	IN
cord-350019-4nlbu54e	524	25	human	human	JJ
cord-350019-4nlbu54e	524	26	long	long	JJ
cord-350019-4nlbu54e	524	27	non	non	JJ
cord-350019-4nlbu54e	524	28	-	-	JJ
cord-350019-4nlbu54e	524	29	coding	coding	JJ
cord-350019-4nlbu54e	524	30	RNAs	rna	NNS
cord-350019-4nlbu54e	524	31	using	use	VBG
cord-350019-4nlbu54e	524	32	a	a	DT
cord-350019-4nlbu54e	524	33	paired	pair	VBN
cord-350019-4nlbu54e	524	34	-	-	HYPH
cord-350019-4nlbu54e	524	35	guide	guide	NN
cord-350019-4nlbu54e	524	36	RNA	RNA	NNP
cord-350019-4nlbu54e	524	37	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	524	38	-	-	HYPH
cord-350019-4nlbu54e	524	39	Cas9	Cas9	NNP
cord-350019-4nlbu54e	524	40	library	library	NN
cord-350019-4nlbu54e	524	41	Considerations	consideration	NNS
cord-350019-4nlbu54e	524	42	when	when	WRB
cord-350019-4nlbu54e	524	43	investigating	investigate	VBG
cord-350019-4nlbu54e	524	44	lncRNA	lncrna	NN
cord-350019-4nlbu54e	524	45	function	function	NN
cord-350019-4nlbu54e	524	46	in	in	IN
cord-350019-4nlbu54e	524	47	vivo	vivo	NNP
cord-350019-4nlbu54e	524	48	Genome	Genome	NNP
cord-350019-4nlbu54e	524	49	-	-	HYPH
cord-350019-4nlbu54e	524	50	wide	wide	JJ
cord-350019-4nlbu54e	524	51	screening	screening	NN
cord-350019-4nlbu54e	524	52	for	for	IN
cord-350019-4nlbu54e	524	53	functional	functional	JJ
cord-350019-4nlbu54e	524	54	long	long	JJ
cord-350019-4nlbu54e	524	55	noncoding	noncoding	JJ
cord-350019-4nlbu54e	524	56	RNAs	rna	NNS
cord-350019-4nlbu54e	524	57	in	in	IN
cord-350019-4nlbu54e	524	58	human	human	JJ
cord-350019-4nlbu54e	524	59	cells	cell	NNS
cord-350019-4nlbu54e	524	60	by	by	IN
cord-350019-4nlbu54e	524	61	Cas9	Cas9	NNP
cord-350019-4nlbu54e	524	62	targeting	targeting	NN
cord-350019-4nlbu54e	524	63	of	of	IN
cord-350019-4nlbu54e	524	64	splice	splice	NN
cord-350019-4nlbu54e	524	65	sites	site	NNS
cord-350019-4nlbu54e	525	1	Frameshift	frameshift	NN
cord-350019-4nlbu54e	525	2	indels	indel	NNS
cord-350019-4nlbu54e	525	3	introduced	introduce	VBN
cord-350019-4nlbu54e	525	4	by	by	IN
cord-350019-4nlbu54e	525	5	genome	genome	NN
cord-350019-4nlbu54e	525	6	editing	editing	NN
cord-350019-4nlbu54e	525	7	can	can	MD
cord-350019-4nlbu54e	525	8	lead	lead	VB
cord-350019-4nlbu54e	525	9	to	to	IN
cord-350019-4nlbu54e	525	10	inframe	inframe	NN
cord-350019-4nlbu54e	525	11	exon	exon	NN
cord-350019-4nlbu54e	525	12	skipping	skip	VBG
cord-350019-4nlbu54e	525	13	Genome	genome	NN
cord-350019-4nlbu54e	525	14	-	-	HYPH
cord-350019-4nlbu54e	525	15	scale	scale	NN
cord-350019-4nlbu54e	525	16	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	525	17	-	-	HYPH
cord-350019-4nlbu54e	525	18	mediated	mediate	VBN
cord-350019-4nlbu54e	525	19	control	control	NN
cord-350019-4nlbu54e	525	20	of	of	IN
cord-350019-4nlbu54e	525	21	gene	gene	NN
cord-350019-4nlbu54e	525	22	repression	repression	NN
cord-350019-4nlbu54e	525	23	and	and	CC
cord-350019-4nlbu54e	525	24	activation	activation	NN
cord-350019-4nlbu54e	525	25	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	525	26	interference	interference	NN
cord-350019-4nlbu54e	525	27	(	(	-LRB-
cord-350019-4nlbu54e	525	28	CRISPRi	crispri	NN
cord-350019-4nlbu54e	525	29	)	)	-RRB-
cord-350019-4nlbu54e	525	30	for	for	IN
cord-350019-4nlbu54e	525	31	sequence	sequence	NN
cord-350019-4nlbu54e	525	32	-	-	HYPH
cord-350019-4nlbu54e	525	33	specific	specific	JJ
cord-350019-4nlbu54e	525	34	control	control	NN
cord-350019-4nlbu54e	525	35	of	of	IN
cord-350019-4nlbu54e	525	36	gene	gene	NN
cord-350019-4nlbu54e	525	37	expression	expression	NN
cord-350019-4nlbu54e	526	1	The	the	DT
cord-350019-4nlbu54e	526	2	Krüppel	Krüppel	NNP
cord-350019-4nlbu54e	526	3	-	-	HYPH
cord-350019-4nlbu54e	526	4	associated	associate	VBN
cord-350019-4nlbu54e	526	5	box	box	NN
cord-350019-4nlbu54e	526	6	repressor	repressor	NN
cord-350019-4nlbu54e	526	7	domain	domain	NN
cord-350019-4nlbu54e	526	8	induces	induce	VBZ
cord-350019-4nlbu54e	526	9	reversible	reversible	JJ
cord-350019-4nlbu54e	526	10	and	and	CC
cord-350019-4nlbu54e	526	11	irreversible	irreversible	JJ
cord-350019-4nlbu54e	526	12	regulation	regulation	NN
cord-350019-4nlbu54e	526	13	of	of	IN
cord-350019-4nlbu54e	526	14	endogenous	endogenous	JJ
cord-350019-4nlbu54e	526	15	mouse	mouse	NN
cord-350019-4nlbu54e	526	16	genes	gene	NNS
cord-350019-4nlbu54e	526	17	by	by	IN
cord-350019-4nlbu54e	526	18	mediating	mediate	VBG
cord-350019-4nlbu54e	526	19	different	different	JJ
cord-350019-4nlbu54e	526	20	chromatin	chromatin	NN
cord-350019-4nlbu54e	526	21	states	state	NNS
cord-350019-4nlbu54e	526	22	Gene	Gene	NNP
cord-350019-4nlbu54e	526	23	overexpression	overexpression	NN
cord-350019-4nlbu54e	526	24	:	:	:
cord-350019-4nlbu54e	526	25	uses	use	NNS
cord-350019-4nlbu54e	526	26	,	,	,
cord-350019-4nlbu54e	526	27	mechanisms	mechanism	NNS
cord-350019-4nlbu54e	526	28	,	,	,
cord-350019-4nlbu54e	526	29	and	and	CC
cord-350019-4nlbu54e	526	30	interpretation	interpretation	NN
cord-350019-4nlbu54e	526	31	Multiplexed	Multiplexed	NNP
cord-350019-4nlbu54e	526	32	activation	activation	NN
cord-350019-4nlbu54e	526	33	of	of	IN
cord-350019-4nlbu54e	526	34	endogenous	endogenous	JJ
cord-350019-4nlbu54e	526	35	genes	gene	NNS
cord-350019-4nlbu54e	526	36	by	by	IN
cord-350019-4nlbu54e	526	37	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	526	38	-	-	HYPH
cord-350019-4nlbu54e	526	39	on	on	RP
cord-350019-4nlbu54e	526	40	,	,	,
cord-350019-4nlbu54e	526	41	an	an	DT
cord-350019-4nlbu54e	526	42	RNA	RNA	NNP
cord-350019-4nlbu54e	526	43	-	-	HYPH
cord-350019-4nlbu54e	526	44	guided	guide	VBN
cord-350019-4nlbu54e	526	45	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	526	46	activator	activator	NN
cord-350019-4nlbu54e	526	47	system	system	NN
cord-350019-4nlbu54e	526	48	CRISPR	CRISPR	NNP
cord-350019-4nlbu54e	526	49	-	-	HYPH
cord-350019-4nlbu54e	526	50	mediated	mediate	VBN
cord-350019-4nlbu54e	526	51	modular	modular	JJ
cord-350019-4nlbu54e	526	52	RNA	RNA	NNP
cord-350019-4nlbu54e	526	53	-	-	HYPH
cord-350019-4nlbu54e	526	54	guided	guide	VBN
cord-350019-4nlbu54e	526	55	regulation	regulation	NN
cord-350019-4nlbu54e	526	56	of	of	IN
cord-350019-4nlbu54e	526	57	transcription	transcription	NN
cord-350019-4nlbu54e	526	58	in	in	IN
cord-350019-4nlbu54e	526	59	eukaryotes	eukaryote	NNS
cord-350019-4nlbu54e	527	1	Genome	genome	NN
cord-350019-4nlbu54e	527	2	-	-	HYPH
cord-350019-4nlbu54e	527	3	scale	scale	NN
cord-350019-4nlbu54e	527	4	activation	activation	NN
cord-350019-4nlbu54e	527	5	screen	screen	NN
cord-350019-4nlbu54e	527	6	identifies	identify	VBZ
cord-350019-4nlbu54e	527	7	a	a	DT
cord-350019-4nlbu54e	527	8	lncRNA	lncrna	NN
cord-350019-4nlbu54e	527	9	locus	locus	NN
cord-350019-4nlbu54e	527	10	regulating	regulate	VBG
cord-350019-4nlbu54e	527	11	a	a	DT
cord-350019-4nlbu54e	527	12	gene	gene	NN
cord-350019-4nlbu54e	527	13	neighbourhood	neighbourhood	NN
cord-350019-4nlbu54e	527	14	Linking	link	VBG
cord-350019-4nlbu54e	527	15	RNA	RNA	NNP
cord-350019-4nlbu54e	527	16	biology	biology	NN
cord-350019-4nlbu54e	527	17	to	to	IN
cord-350019-4nlbu54e	527	18	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	528	1	Promoter	Promoter	NNP
cord-350019-4nlbu54e	528	2	of	of	IN
cord-350019-4nlbu54e	528	3	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	528	4	gene	gene	NNP
cord-350019-4nlbu54e	528	5	PVT1	PVT1	NNP
cord-350019-4nlbu54e	528	6	is	be	VBZ
cord-350019-4nlbu54e	528	7	a	a	DT
cord-350019-4nlbu54e	528	8	tumor	tumor	NN
cord-350019-4nlbu54e	528	9	-	-	HYPH
cord-350019-4nlbu54e	528	10	suppressor	suppressor	NN
cord-350019-4nlbu54e	528	11	DNA	dna	NN
cord-350019-4nlbu54e	528	12	boundary	boundary	NN
cord-350019-4nlbu54e	528	13	element	element	NN
cord-350019-4nlbu54e	528	14	Unlinking	unlinke	VBG
cord-350019-4nlbu54e	528	15	an	an	DT
cord-350019-4nlbu54e	528	16	lncRNA	lncrna	NN
cord-350019-4nlbu54e	528	17	from	from	IN
cord-350019-4nlbu54e	529	1	its	-PRON-	PRP$
cord-350019-4nlbu54e	529	2	associated	associated	NNP
cord-350019-4nlbu54e	529	3	cis	cis	NNP
cord-350019-4nlbu54e	529	4	element	element	NN
cord-350019-4nlbu54e	529	5	Multiple	multiple	JJ
cord-350019-4nlbu54e	529	6	knockout	knockout	NN
cord-350019-4nlbu54e	529	7	mouse	mouse	NN
cord-350019-4nlbu54e	529	8	models	model	NNS
cord-350019-4nlbu54e	529	9	reveal	reveal	VBP
cord-350019-4nlbu54e	529	10	lincRNAs	lincrnas	PRP
cord-350019-4nlbu54e	529	11	are	be	VBP
cord-350019-4nlbu54e	529	12	required	require	VBN
cord-350019-4nlbu54e	529	13	for	for	IN
cord-350019-4nlbu54e	529	14	life	life	NN
cord-350019-4nlbu54e	529	15	and	and	CC
cord-350019-4nlbu54e	529	16	brain	brain	NN
cord-350019-4nlbu54e	529	17	development	development	NN
cord-350019-4nlbu54e	530	1	Xist	xist	VB
cord-350019-4nlbu54e	530	2	-	-	HYPH
cord-350019-4nlbu54e	530	3	deficient	deficient	JJ
cord-350019-4nlbu54e	530	4	mice	mouse	NNS
cord-350019-4nlbu54e	530	5	are	be	VBP
cord-350019-4nlbu54e	530	6	defective	defective	JJ
cord-350019-4nlbu54e	530	7	in	in	IN
cord-350019-4nlbu54e	530	8	dosage	dosage	NN
cord-350019-4nlbu54e	530	9	compensation	compensation	NN
cord-350019-4nlbu54e	530	10	but	but	CC
cord-350019-4nlbu54e	530	11	not	not	RB
cord-350019-4nlbu54e	530	12	spermatogenesis	spermatogenesis	NN
cord-350019-4nlbu54e	530	13	Deletion	deletion	NN
cord-350019-4nlbu54e	530	14	of	of	IN
cord-350019-4nlbu54e	530	15	the	the	DT
cord-350019-4nlbu54e	530	16	H19	H19	NNP
cord-350019-4nlbu54e	530	17	transcription	transcription	NN
cord-350019-4nlbu54e	530	18	unit	unit	NN
cord-350019-4nlbu54e	530	19	reveals	reveal	VBZ
cord-350019-4nlbu54e	530	20	the	the	DT
cord-350019-4nlbu54e	530	21	existence	existence	NN
cord-350019-4nlbu54e	530	22	of	of	IN
cord-350019-4nlbu54e	530	23	a	a	DT
cord-350019-4nlbu54e	530	24	putative	putative	JJ
cord-350019-4nlbu54e	530	25	imprinting	imprinting	NN
cord-350019-4nlbu54e	530	26	control	control	NN
cord-350019-4nlbu54e	530	27	element	element	NN
cord-350019-4nlbu54e	530	28	The	the	DT
cord-350019-4nlbu54e	530	29	roX	rox	JJ
cord-350019-4nlbu54e	530	30	genes	gene	NNS
cord-350019-4nlbu54e	530	31	encode	encode	VBP
cord-350019-4nlbu54e	530	32	redundant	redundant	JJ
cord-350019-4nlbu54e	530	33	male	male	NN
cord-350019-4nlbu54e	530	34	-	-	HYPH
cord-350019-4nlbu54e	530	35	specific	specific	JJ
cord-350019-4nlbu54e	530	36	lethal	lethal	JJ
cord-350019-4nlbu54e	530	37	transcripts	transcript	NNS
cord-350019-4nlbu54e	530	38	required	require	VBN
cord-350019-4nlbu54e	530	39	for	for	IN
cord-350019-4nlbu54e	530	40	targeting	targeting	NN
cord-350019-4nlbu54e	530	41	of	of	IN
cord-350019-4nlbu54e	530	42	the	the	DT
cord-350019-4nlbu54e	530	43	MSL	MSL	NNP
cord-350019-4nlbu54e	530	44	complex	complex	NN
cord-350019-4nlbu54e	530	45	Loss	loss	NN
cord-350019-4nlbu54e	530	46	of	of	IN
cord-350019-4nlbu54e	530	47	the	the	DT
cord-350019-4nlbu54e	530	48	abundant	abundant	JJ
cord-350019-4nlbu54e	530	49	nuclear	nuclear	JJ
cord-350019-4nlbu54e	530	50	non	non	JJ
cord-350019-4nlbu54e	530	51	-	-	JJ
cord-350019-4nlbu54e	530	52	coding	coding	JJ
cord-350019-4nlbu54e	530	53	RNA	rna	NN
cord-350019-4nlbu54e	530	54	MALAT1	malat1	NN
cord-350019-4nlbu54e	530	55	is	be	VBZ
cord-350019-4nlbu54e	530	56	compatible	compatible	JJ
cord-350019-4nlbu54e	530	57	with	with	IN
cord-350019-4nlbu54e	530	58	life	life	NN
cord-350019-4nlbu54e	530	59	and	and	CC
cord-350019-4nlbu54e	530	60	development	development	NN
cord-350019-4nlbu54e	530	61	Targeted	target	VBN
cord-350019-4nlbu54e	530	62	disruption	disruption	NN
cord-350019-4nlbu54e	530	63	of	of	IN
cord-350019-4nlbu54e	530	64	Hotair	Hotair	NNP
cord-350019-4nlbu54e	530	65	leads	lead	VBZ
cord-350019-4nlbu54e	530	66	to	to	IN
cord-350019-4nlbu54e	530	67	homeotic	homeotic	JJ
cord-350019-4nlbu54e	530	68	transformation	transformation	NN
cord-350019-4nlbu54e	530	69	and	and	CC
cord-350019-4nlbu54e	530	70	gene	gene	NN
cord-350019-4nlbu54e	530	71	derepression	derepression	NNP
cord-350019-4nlbu54e	531	1	The	the	DT
cord-350019-4nlbu54e	531	2	tissue	tissue	NN
cord-350019-4nlbu54e	531	3	-	-	HYPH
cord-350019-4nlbu54e	531	4	specific	specific	JJ
cord-350019-4nlbu54e	531	5	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	531	6	Fendrr	Fendrr	NNP
cord-350019-4nlbu54e	531	7	is	be	VBZ
cord-350019-4nlbu54e	531	8	an	an	DT
cord-350019-4nlbu54e	531	9	essential	essential	JJ
cord-350019-4nlbu54e	531	10	regulator	regulator	NN
cord-350019-4nlbu54e	531	11	of	of	IN
cord-350019-4nlbu54e	531	12	heart	heart	NN
cord-350019-4nlbu54e	531	13	and	and	CC
cord-350019-4nlbu54e	531	14	body	body	NN
cord-350019-4nlbu54e	531	15	wall	wall	NN
cord-350019-4nlbu54e	531	16	development	development	NN
cord-350019-4nlbu54e	531	17	in	in	IN
cord-350019-4nlbu54e	531	18	the	the	DT
cord-350019-4nlbu54e	531	19	mouse	mouse	NN
cord-350019-4nlbu54e	531	20	Genomic	Genomic	NNP
cord-350019-4nlbu54e	531	21	and	and	CC
cord-350019-4nlbu54e	531	22	epigenetic	epigenetic	JJ
cord-350019-4nlbu54e	531	23	complexity	complexity	NN
cord-350019-4nlbu54e	531	24	of	of	IN
cord-350019-4nlbu54e	531	25	the	the	DT
cord-350019-4nlbu54e	531	26	FOXF1	FOXF1	NNP
cord-350019-4nlbu54e	531	27	locus	locus	NN
cord-350019-4nlbu54e	531	28	in	in	IN
cord-350019-4nlbu54e	531	29	16q24.1	16q24.1	CD
cord-350019-4nlbu54e	531	30	:	:	:
cord-350019-4nlbu54e	531	31	implications	implication	NNS
cord-350019-4nlbu54e	531	32	for	for	IN
cord-350019-4nlbu54e	531	33	development	development	NN
cord-350019-4nlbu54e	531	34	and	and	CC
cord-350019-4nlbu54e	531	35	disease	disease	NN
cord-350019-4nlbu54e	531	36	Transcription	transcription	NN
cord-350019-4nlbu54e	531	37	factor	factor	NN
cord-350019-4nlbu54e	532	1	IRF8	IRF8	NNP
cord-350019-4nlbu54e	532	2	plays	play	VBZ
cord-350019-4nlbu54e	532	3	a	a	DT
cord-350019-4nlbu54e	532	4	critical	critical	JJ
cord-350019-4nlbu54e	532	5	role	role	NN
cord-350019-4nlbu54e	532	6	in	in	IN
cord-350019-4nlbu54e	532	7	the	the	DT
cord-350019-4nlbu54e	532	8	development	development	NN
cord-350019-4nlbu54e	532	9	of	of	IN
cord-350019-4nlbu54e	532	10	murine	murine	JJ
cord-350019-4nlbu54e	532	11	basophils	basophil	NNS
cord-350019-4nlbu54e	532	12	and	and	CC
cord-350019-4nlbu54e	532	13	mast	mast	NN
cord-350019-4nlbu54e	532	14	cells	cell	NNS
cord-350019-4nlbu54e	532	15	Balanced	balanced	JJ
cord-350019-4nlbu54e	532	16	gene	gene	NN
cord-350019-4nlbu54e	532	17	regulation	regulation	NN
cord-350019-4nlbu54e	532	18	by	by	IN
cord-350019-4nlbu54e	532	19	an	an	DT
cord-350019-4nlbu54e	532	20	embryonic	embryonic	JJ
cord-350019-4nlbu54e	532	21	brain	brain	NN
cord-350019-4nlbu54e	532	22	ncRNA	ncRNA	.
cord-350019-4nlbu54e	533	1	is	be	VBZ
cord-350019-4nlbu54e	533	2	critical	critical	JJ
cord-350019-4nlbu54e	533	3	for	for	IN
cord-350019-4nlbu54e	533	4	adult	adult	NN
cord-350019-4nlbu54e	533	5	hippocampal	hippocampal	JJ
cord-350019-4nlbu54e	533	6	GABA	GABA	NNP
cord-350019-4nlbu54e	533	7	circuitry	circuitry	NN
cord-350019-4nlbu54e	533	8	Evf2	Evf2	NNP
cord-350019-4nlbu54e	533	9	(	(	-LRB-
cord-350019-4nlbu54e	533	10	Dlx6as	dlx6as	FW
cord-350019-4nlbu54e	533	11	)	)	-RRB-
cord-350019-4nlbu54e	533	12	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	533	13	regulates	regulate	VBZ
cord-350019-4nlbu54e	533	14	ultraconserved	ultraconserved	JJ
cord-350019-4nlbu54e	533	15	enhancer	enhancer	NN
cord-350019-4nlbu54e	533	16	methylation	methylation	NN
cord-350019-4nlbu54e	533	17	and	and	CC
cord-350019-4nlbu54e	533	18	the	the	DT
cord-350019-4nlbu54e	533	19	differential	differential	JJ
cord-350019-4nlbu54e	533	20	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	533	21	control	control	NN
cord-350019-4nlbu54e	533	22	of	of	IN
cord-350019-4nlbu54e	533	23	adjacent	adjacent	JJ
cord-350019-4nlbu54e	533	24	genes	gene	NNS
cord-350019-4nlbu54e	534	1	LncRNA	LncRNA	NNP
cord-350019-4nlbu54e	534	2	Jpx	Jpx	NNP
cord-350019-4nlbu54e	534	3	induces	induce	VBZ
cord-350019-4nlbu54e	534	4	Xist	Xist	NNP
cord-350019-4nlbu54e	534	5	expression	expression	NN
cord-350019-4nlbu54e	534	6	in	in	IN
cord-350019-4nlbu54e	534	7	mice	mouse	NNS
cord-350019-4nlbu54e	534	8	using	use	VBG
cord-350019-4nlbu54e	534	9	both	both	CC
cord-350019-4nlbu54e	534	10	trans	trans	NNP
cord-350019-4nlbu54e	534	11	and	and	CC
cord-350019-4nlbu54e	534	12	cis	cis	NNP
cord-350019-4nlbu54e	534	13	mechanisms	mechanism	NNS
cord-350019-4nlbu54e	535	1	The	the	DT
cord-350019-4nlbu54e	535	2	long	long	JJ
cord-350019-4nlbu54e	535	3	noncoding	noncoding	JJ
cord-350019-4nlbu54e	535	4	RNA	RNA	NNP
cord-350019-4nlbu54e	535	5	Pnky	Pnky	NNP
cord-350019-4nlbu54e	535	6	is	be	VBZ
cord-350019-4nlbu54e	535	7	a	a	DT
cord-350019-4nlbu54e	535	8	trans	trans	JJ
cord-350019-4nlbu54e	535	9	-	-	JJ
cord-350019-4nlbu54e	535	10	acting	acting	JJ
cord-350019-4nlbu54e	535	11	regulator	regulator	NN
cord-350019-4nlbu54e	535	12	of	of	IN
cord-350019-4nlbu54e	535	13	cortical	cortical	JJ
cord-350019-4nlbu54e	535	14	development	development	NN
cord-350019-4nlbu54e	535	15	in	in	IN
cord-350019-4nlbu54e	535	16	vivo	vivo	NNP
cord-350019-4nlbu54e	536	1	ChIRP	ChIRP	NNP
cord-350019-4nlbu54e	536	2	-	-	HYPH
cord-350019-4nlbu54e	536	3	MS	MS	NNP
cord-350019-4nlbu54e	536	4	:	:	:
cord-350019-4nlbu54e	536	5	RNA	rna	NN
cord-350019-4nlbu54e	536	6	-	-	HYPH
cord-350019-4nlbu54e	536	7	directed	direct	VBN
cord-350019-4nlbu54e	536	8	proteomic	proteomic	JJ
cord-350019-4nlbu54e	536	9	discovery	discovery	NN
cord-350019-4nlbu54e	537	1	Chromatin	Chromatin	NNP
cord-350019-4nlbu54e	537	2	isolation	isolation	NN
cord-350019-4nlbu54e	537	3	by	by	IN
cord-350019-4nlbu54e	537	4	RNA	RNA	NNP
cord-350019-4nlbu54e	537	5	purification	purification	NN
cord-350019-4nlbu54e	538	1	(	(	-LRB-
cord-350019-4nlbu54e	538	2	ChIRP	ChIRP	NNP
cord-350019-4nlbu54e	538	3	)	)	-RRB-
cord-350019-4nlbu54e	538	4	RAP	RAP	NNP
cord-350019-4nlbu54e	538	5	-	-	HYPH
cord-350019-4nlbu54e	538	6	MS	MS	NNP
cord-350019-4nlbu54e	538	7	:	:	:
cord-350019-4nlbu54e	538	8	a	a	DT
cord-350019-4nlbu54e	538	9	method	method	NN
cord-350019-4nlbu54e	538	10	to	to	TO
cord-350019-4nlbu54e	538	11	identify	identify	VB
cord-350019-4nlbu54e	538	12	proteins	protein	NNS
cord-350019-4nlbu54e	538	13	that	that	WDT
cord-350019-4nlbu54e	538	14	interact	interact	VBP
cord-350019-4nlbu54e	538	15	directly	directly	RB
cord-350019-4nlbu54e	538	16	with	with	IN
cord-350019-4nlbu54e	538	17	a	a	DT
cord-350019-4nlbu54e	538	18	specific	specific	JJ
cord-350019-4nlbu54e	538	19	RNA	RNA	NNP
cord-350019-4nlbu54e	538	20	molecule	molecule	NN
cord-350019-4nlbu54e	538	21	in	in	IN
cord-350019-4nlbu54e	538	22	cells	cell	NNS
cord-350019-4nlbu54e	539	1	RNA	RNA	NNP
cord-350019-4nlbu54e	539	2	-	-	HYPH
cord-350019-4nlbu54e	539	3	RNA	RNA	NNP
cord-350019-4nlbu54e	539	4	interactions	interaction	NNS
cord-350019-4nlbu54e	539	5	enable	enable	VBP
cord-350019-4nlbu54e	539	6	specific	specific	JJ
cord-350019-4nlbu54e	539	7	targeting	targeting	NN
cord-350019-4nlbu54e	539	8	of	of	IN
cord-350019-4nlbu54e	539	9	noncoding	noncoding	JJ
cord-350019-4nlbu54e	539	10	RNAs	rna	NNS
cord-350019-4nlbu54e	539	11	to	to	IN
cord-350019-4nlbu54e	539	12	nascent	nascent	JJ
cord-350019-4nlbu54e	539	13	pre	pre	NN
cord-350019-4nlbu54e	539	14	-	-	JJ
cord-350019-4nlbu54e	539	15	mRNAs	mrna	NNS
cord-350019-4nlbu54e	539	16	and	and	CC
cord-350019-4nlbu54e	539	17	chromatin	chromatin	NN
cord-350019-4nlbu54e	539	18	sites	site	NNS
cord-350019-4nlbu54e	539	19	RNA	RNA	NNP
cord-350019-4nlbu54e	539	20	pull	pull	NN
cord-350019-4nlbu54e	539	21	-	-	HYPH
cord-350019-4nlbu54e	539	22	down	down	RP
cord-350019-4nlbu54e	539	23	procedure	procedure	NN
cord-350019-4nlbu54e	539	24	to	to	TO
cord-350019-4nlbu54e	539	25	identify	identify	VB
cord-350019-4nlbu54e	539	26	RNA	RNA	NNP
cord-350019-4nlbu54e	539	27	targets	target	NNS
cord-350019-4nlbu54e	539	28	of	of	IN
cord-350019-4nlbu54e	539	29	a	a	DT
cord-350019-4nlbu54e	539	30	long	long	JJ
cord-350019-4nlbu54e	539	31	noncoding	noncoding	JJ
cord-350019-4nlbu54e	539	32	RNA	rna	NN
cord-350019-4nlbu54e	539	33	Zbtb7b	Zbtb7b	NNP
cord-350019-4nlbu54e	539	34	engages	engage	VBZ
cord-350019-4nlbu54e	539	35	the	the	DT
cord-350019-4nlbu54e	539	36	long	long	JJ
cord-350019-4nlbu54e	539	37	noncoding	noncoding	JJ
cord-350019-4nlbu54e	539	38	RNA	RNA	NNP
cord-350019-4nlbu54e	539	39	Blnc1	Blnc1	NNP
cord-350019-4nlbu54e	539	40	to	to	TO
cord-350019-4nlbu54e	539	41	drive	drive	VB
cord-350019-4nlbu54e	539	42	brown	brown	JJ
cord-350019-4nlbu54e	539	43	and	and	CC
cord-350019-4nlbu54e	539	44	beige	beige	JJ
cord-350019-4nlbu54e	539	45	fat	fat	NN
cord-350019-4nlbu54e	539	46	development	development	NN
cord-350019-4nlbu54e	539	47	and	and	CC
cord-350019-4nlbu54e	539	48	thermogenesis	thermogenesis	NN
cord-350019-4nlbu54e	539	49	CatRAPID	catrapid	NN
cord-350019-4nlbu54e	539	50	omics	omic	NNS
cord-350019-4nlbu54e	539	51	:	:	:
cord-350019-4nlbu54e	539	52	a	a	DT
cord-350019-4nlbu54e	539	53	web	web	NN
cord-350019-4nlbu54e	539	54	server	server	NN
cord-350019-4nlbu54e	539	55	for	for	IN
cord-350019-4nlbu54e	539	56	large	large	JJ
cord-350019-4nlbu54e	539	57	-	-	HYPH
cord-350019-4nlbu54e	539	58	scale	scale	NN
cord-350019-4nlbu54e	539	59	prediction	prediction	NN
cord-350019-4nlbu54e	539	60	of	of	IN
cord-350019-4nlbu54e	539	61	protein	protein	NN
cord-350019-4nlbu54e	539	62	-	-	HYPH
cord-350019-4nlbu54e	539	63	RNA	RNA	NNP
cord-350019-4nlbu54e	539	64	interactions	interaction	NNS
cord-350019-4nlbu54e	539	65	OMICtools	omictool	NNS
cord-350019-4nlbu54e	539	66	:	:	:
cord-350019-4nlbu54e	539	67	an	an	DT
cord-350019-4nlbu54e	539	68	informative	informative	JJ
cord-350019-4nlbu54e	539	69	directory	directory	NN
cord-350019-4nlbu54e	539	70	for	for	IN
cord-350019-4nlbu54e	539	71	multi	multi	JJ
cord-350019-4nlbu54e	539	72	-	-	JJ
cord-350019-4nlbu54e	539	73	omic	omic	JJ
cord-350019-4nlbu54e	539	74	data	datum	NNS
cord-350019-4nlbu54e	539	75	analysis	analysis	NN
cord-350019-4nlbu54e	539	76	,	,	,
cord-350019-4nlbu54e	539	77	Database	Database	NNP
cord-350019-4nlbu54e	539	78	(	(	-LRB-
cord-350019-4nlbu54e	539	79	Oxford	Oxford	NNP
cord-350019-4nlbu54e	539	80	)	)	-RRB-
cord-350019-4nlbu54e	540	1	The	the	DT
cord-350019-4nlbu54e	540	2	emerging	emerge	VBG
cord-350019-4nlbu54e	540	3	role	role	NN
cord-350019-4nlbu54e	540	4	of	of	IN
cord-350019-4nlbu54e	540	5	exosome	exosome	NN
cord-350019-4nlbu54e	540	6	-	-	HYPH
cord-350019-4nlbu54e	540	7	derived	derive	VBN
cord-350019-4nlbu54e	540	8	non	non	JJ
cord-350019-4nlbu54e	540	9	-	-	JJ
cord-350019-4nlbu54e	540	10	coding	coding	JJ
cord-350019-4nlbu54e	540	11	RNAs	rna	NNS
cord-350019-4nlbu54e	540	12	in	in	IN
cord-350019-4nlbu54e	540	13	cancer	cancer	NN
cord-350019-4nlbu54e	540	14	biology	biology	NN
cord-350019-4nlbu54e	540	15	Global	global	JJ
cord-350019-4nlbu54e	540	16	positioning	positioning	NN
cord-350019-4nlbu54e	540	17	system	system	NN
cord-350019-4nlbu54e	540	18	:	:	:
cord-350019-4nlbu54e	540	19	understanding	understand	VBG
cord-350019-4nlbu54e	540	20	long	long	JJ
cord-350019-4nlbu54e	540	21	noncoding	noncoding	JJ
cord-350019-4nlbu54e	540	22	RNAs	rna	NNS
cord-350019-4nlbu54e	540	23	through	through	IN
cord-350019-4nlbu54e	540	24	subcellular	subcellular	JJ
cord-350019-4nlbu54e	540	25	localization	localization	NN
cord-350019-4nlbu54e	540	26	Cytoplasmic	Cytoplasmic	NNP
cord-350019-4nlbu54e	540	27	functions	function	NNS
cord-350019-4nlbu54e	540	28	of	of	IN
cord-350019-4nlbu54e	540	29	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	540	30	Nuclear	Nuclear	NNP
cord-350019-4nlbu54e	540	31	long	long	JJ
cord-350019-4nlbu54e	540	32	noncoding	noncoding	JJ
cord-350019-4nlbu54e	540	33	RNAs	rna	NNS
cord-350019-4nlbu54e	540	34	:	:	:
cord-350019-4nlbu54e	540	35	key	key	JJ
cord-350019-4nlbu54e	540	36	regulators	regulator	NNS
cord-350019-4nlbu54e	540	37	of	of	IN
cord-350019-4nlbu54e	540	38	gene	gene	NN
cord-350019-4nlbu54e	540	39	expression	expression	NN
cord-350019-4nlbu54e	540	40	Plasma	Plasma	NNP
cord-350019-4nlbu54e	540	41	long	long	RB
cord-350019-4nlbu54e	540	42	noncoding	noncoding	JJ
cord-350019-4nlbu54e	540	43	RNA	RNA	NNP
cord-350019-4nlbu54e	541	1	IL-7R	IL-7R	NNP
cord-350019-4nlbu54e	541	2	as	as	IN
cord-350019-4nlbu54e	541	3	a	a	DT
cord-350019-4nlbu54e	541	4	prognostic	prognostic	JJ
cord-350019-4nlbu54e	541	5	biomarker	biomarker	NN
cord-350019-4nlbu54e	541	6	for	for	IN
cord-350019-4nlbu54e	541	7	clinical	clinical	JJ
cord-350019-4nlbu54e	541	8	outcomes	outcome	NNS
cord-350019-4nlbu54e	541	9	in	in	IN
cord-350019-4nlbu54e	541	10	patients	patient	NNS
cord-350019-4nlbu54e	541	11	with	with	IN
cord-350019-4nlbu54e	541	12	acute	acute	JJ
cord-350019-4nlbu54e	541	13	respiratory	respiratory	JJ
cord-350019-4nlbu54e	541	14	distress	distress	NN
cord-350019-4nlbu54e	541	15	syndrome	syndrome	NN
cord-350019-4nlbu54e	542	1	A	a	DT
cord-350019-4nlbu54e	542	2	feedforward	feedforward	NN
cord-350019-4nlbu54e	542	3	regulatory	regulatory	JJ
cord-350019-4nlbu54e	542	4	loop	loop	NN
cord-350019-4nlbu54e	542	5	between	between	IN
cord-350019-4nlbu54e	542	6	HuR	hur	NN
cord-350019-4nlbu54e	542	7	and	and	CC
cord-350019-4nlbu54e	542	8	the	the	DT
cord-350019-4nlbu54e	542	9	long	long	JJ
cord-350019-4nlbu54e	542	10	noncoding	noncoding	NNP
cord-350019-4nlbu54e	542	11	RNA	RNA	NNP
cord-350019-4nlbu54e	542	12	linc	linc	NNP
cord-350019-4nlbu54e	542	13	-	-	HYPH
cord-350019-4nlbu54e	542	14	MD1	MD1	NNP
cord-350019-4nlbu54e	542	15	controls	control	VBZ
cord-350019-4nlbu54e	542	16	early	early	JJ
cord-350019-4nlbu54e	542	17	phases	phase	NNS
cord-350019-4nlbu54e	542	18	of	of	IN
cord-350019-4nlbu54e	542	19	myogenesis	myogenesis	NNP
cord-350019-4nlbu54e	543	1	A	a	DT
cord-350019-4nlbu54e	543	2	long	long	JJ
cord-350019-4nlbu54e	543	3	noncoding	noncoding	JJ
cord-350019-4nlbu54e	543	4	RNA	RNA	NNP
cord-350019-4nlbu54e	543	5	controls	control	VBZ
cord-350019-4nlbu54e	543	6	muscle	muscle	NN
cord-350019-4nlbu54e	543	7	differentiation	differentiation	NN
cord-350019-4nlbu54e	543	8	by	by	IN
cord-350019-4nlbu54e	543	9	functioning	function	VBG
cord-350019-4nlbu54e	543	10	as	as	IN
cord-350019-4nlbu54e	543	11	a	a	DT
cord-350019-4nlbu54e	543	12	competing	compete	VBG
cord-350019-4nlbu54e	543	13	endogenous	endogenous	JJ
cord-350019-4nlbu54e	543	14	RNA	RNA	NNP
cord-350019-4nlbu54e	543	15	ILoc	ILoc	NNP
cord-350019-4nlbu54e	543	16	-	-	HYPH
cord-350019-4nlbu54e	543	17	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	543	18	:	:	:
cord-350019-4nlbu54e	543	19	predict	predict	VB
cord-350019-4nlbu54e	543	20	the	the	DT
cord-350019-4nlbu54e	543	21	subcellular	subcellular	JJ
cord-350019-4nlbu54e	543	22	location	location	NN
cord-350019-4nlbu54e	543	23	of	of	IN
cord-350019-4nlbu54e	543	24	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	543	25	by	by	IN
cord-350019-4nlbu54e	543	26	incorporating	incorporate	VBG
cord-350019-4nlbu54e	543	27	octamer	octamer	NNP
cord-350019-4nlbu54e	543	28	composition	composition	NN
cord-350019-4nlbu54e	543	29	into	into	IN
cord-350019-4nlbu54e	543	30	general	general	JJ
cord-350019-4nlbu54e	543	31	PseKNC	PseKNC	NNP
cord-350019-4nlbu54e	543	32	Atlas	Atlas	NNP
cord-350019-4nlbu54e	543	33	of	of	IN
cord-350019-4nlbu54e	543	34	subcellular	subcellular	JJ
cord-350019-4nlbu54e	543	35	RNA	RNA	NNP
cord-350019-4nlbu54e	543	36	localization	localization	NN
cord-350019-4nlbu54e	543	37	revealed	reveal	VBN
cord-350019-4nlbu54e	543	38	by	by	IN
cord-350019-4nlbu54e	543	39	APEX	APEX	NNP
cord-350019-4nlbu54e	543	40	-	-	HYPH
cord-350019-4nlbu54e	543	41	seq	seq	NN
cord-350019-4nlbu54e	543	42	Co	co	NN
cord-350019-4nlbu54e	543	43	-	-	JJ
cord-350019-4nlbu54e	543	44	transcriptional	transcriptional	JJ
cord-350019-4nlbu54e	543	45	splicing	splicing	NN
cord-350019-4nlbu54e	543	46	of	of	IN
cord-350019-4nlbu54e	543	47	constitutive	constitutive	JJ
cord-350019-4nlbu54e	543	48	and	and	CC
cord-350019-4nlbu54e	543	49	alternative	alternative	JJ
cord-350019-4nlbu54e	543	50	exons	exon	NNS
cord-350019-4nlbu54e	543	51	Sub	sub	JJ
cord-350019-4nlbu54e	543	52	-	-	HYPH
cord-350019-4nlbu54e	543	53	cellular	cellular	JJ
cord-350019-4nlbu54e	543	54	localization	localization	NN
cord-350019-4nlbu54e	543	55	of	of	IN
cord-350019-4nlbu54e	543	56	membrane	membrane	NN
cord-350019-4nlbu54e	543	57	proteins	protein	NNS
cord-350019-4nlbu54e	543	58	Localized	localized	JJ
cord-350019-4nlbu54e	543	59	translation	translation	NN
cord-350019-4nlbu54e	543	60	near	near	IN
cord-350019-4nlbu54e	543	61	the	the	DT
cord-350019-4nlbu54e	543	62	mitochondrial	mitochondrial	JJ
cord-350019-4nlbu54e	543	63	outer	outer	JJ
cord-350019-4nlbu54e	543	64	membrane	membrane	NN
cord-350019-4nlbu54e	543	65	:	:	:
cord-350019-4nlbu54e	543	66	an	an	DT
cord-350019-4nlbu54e	543	67	update	update	NN
cord-350019-4nlbu54e	543	68	Visualization	visualization	NN
cord-350019-4nlbu54e	543	69	of	of	IN
cord-350019-4nlbu54e	543	70	single	single	JJ
cord-350019-4nlbu54e	543	71	RNA	RNA	NNP
cord-350019-4nlbu54e	543	72	transcripts	transcript	NNS
cord-350019-4nlbu54e	543	73	in	in	IN
cord-350019-4nlbu54e	543	74	situ	situ	NN
cord-350019-4nlbu54e	543	75	stable	stable	JJ
cord-350019-4nlbu54e	543	76	In	in	IN
cord-350019-4nlbu54e	543	77	situ	situ	JJ
cord-350019-4nlbu54e	543	78	transcription	transcription	NN
cord-350019-4nlbu54e	543	79	profiling	profiling	NN
cord-350019-4nlbu54e	543	80	of	of	IN
cord-350019-4nlbu54e	543	81	single	single	JJ
cord-350019-4nlbu54e	543	82	cells	cell	NNS
cord-350019-4nlbu54e	544	1	reveals	reveal	VBZ
cord-350019-4nlbu54e	544	2	spatial	spatial	JJ
cord-350019-4nlbu54e	544	3	organization	organization	NN
cord-350019-4nlbu54e	544	4	of	of	IN
cord-350019-4nlbu54e	544	5	cells	cell	NNS
cord-350019-4nlbu54e	544	6	in	in	IN
cord-350019-4nlbu54e	544	7	the	the	DT
cord-350019-4nlbu54e	544	8	mouse	mouse	NN
cord-350019-4nlbu54e	544	9	hippocampus	hippocampus	NN
cord-350019-4nlbu54e	544	10	Immunolabeling	immunolabele	VBG
cord-350019-4nlbu54e	544	11	artifacts	artifact	NNS
cord-350019-4nlbu54e	544	12	and	and	CC
cord-350019-4nlbu54e	544	13	the	the	DT
cord-350019-4nlbu54e	544	14	need	need	NN
cord-350019-4nlbu54e	544	15	for	for	IN
cord-350019-4nlbu54e	544	16	live	live	JJ
cord-350019-4nlbu54e	544	17	-	-	HYPH
cord-350019-4nlbu54e	544	18	cell	cell	NN
cord-350019-4nlbu54e	544	19	imaging	imaging	NN
cord-350019-4nlbu54e	544	20	Evolution	evolution	NN
cord-350019-4nlbu54e	544	21	to	to	IN
cord-350019-4nlbu54e	544	22	the	the	DT
cord-350019-4nlbu54e	544	23	rescue	rescue	NN
cord-350019-4nlbu54e	544	24	:	:	:
cord-350019-4nlbu54e	544	25	using	use	VBG
cord-350019-4nlbu54e	544	26	comparative	comparative	JJ
cord-350019-4nlbu54e	544	27	genomics	genomic	NNS
cord-350019-4nlbu54e	544	28	to	to	TO
cord-350019-4nlbu54e	544	29	understand	understand	VB
cord-350019-4nlbu54e	544	30	long	long	JJ
cord-350019-4nlbu54e	544	31	non	non	JJ
cord-350019-4nlbu54e	544	32	-	-	JJ
cord-350019-4nlbu54e	544	33	coding	coding	JJ
cord-350019-4nlbu54e	544	34	RNAs	rna	NNS
cord-350019-4nlbu54e	545	1	Maternally	Maternally	NNP
cord-350019-4nlbu54e	545	2	expressed	express	VBD
cord-350019-4nlbu54e	545	3	gene	gene	NN
cord-350019-4nlbu54e	545	4	3	3	CD
cord-350019-4nlbu54e	546	1	(	(	-LRB-
cord-350019-4nlbu54e	546	2	MEG3	MEG3	NNP
cord-350019-4nlbu54e	546	3	)	)	-RRB-
cord-350019-4nlbu54e	546	4	noncoding	noncoding	JJ
cord-350019-4nlbu54e	546	5	ribonucleic	ribonucleic	NN
cord-350019-4nlbu54e	546	6	acid	acid	NN
cord-350019-4nlbu54e	546	7	:	:	:
cord-350019-4nlbu54e	546	8	isoform	isoform	NN
cord-350019-4nlbu54e	546	9	structure	structure	NN
cord-350019-4nlbu54e	546	10	,	,	,
cord-350019-4nlbu54e	546	11	expression	expression	NN
cord-350019-4nlbu54e	546	12	,	,	,
cord-350019-4nlbu54e	546	13	and	and	CC
cord-350019-4nlbu54e	546	14	functions	function	VBZ
cord-350019-4nlbu54e	546	15	Structural	structural	JJ
cord-350019-4nlbu54e	546	16	characterization	characterization	NN
cord-350019-4nlbu54e	546	17	of	of	IN
cord-350019-4nlbu54e	546	18	maternally	maternally	RB
cord-350019-4nlbu54e	546	19	expressed	express	VBN
cord-350019-4nlbu54e	546	20	gene	gene	NN
cord-350019-4nlbu54e	546	21	3	3	CD
cord-350019-4nlbu54e	546	22	RNA	RNA	NNP
cord-350019-4nlbu54e	546	23	reveals	reveal	VBZ
cord-350019-4nlbu54e	546	24	conserved	conserve	VBN
cord-350019-4nlbu54e	546	25	motifs	motif	NNS
cord-350019-4nlbu54e	546	26	and	and	CC
cord-350019-4nlbu54e	546	27	potential	potential	JJ
cord-350019-4nlbu54e	546	28	sites	site	NNS
cord-350019-4nlbu54e	546	29	of	of	IN
cord-350019-4nlbu54e	546	30	interaction	interaction	NN
cord-350019-4nlbu54e	546	31	with	with	IN
cord-350019-4nlbu54e	546	32	polycomb	polycomb	NN
cord-350019-4nlbu54e	546	33	repressive	repressive	JJ
cord-350019-4nlbu54e	546	34	complex	complex	JJ
cord-350019-4nlbu54e	546	35	2	2	CD
cord-350019-4nlbu54e	546	36	Non	non	JJ
cord-350019-4nlbu54e	546	37	-	-	JJ
cord-350019-4nlbu54e	546	38	linear	linear	JJ
cord-350019-4nlbu54e	546	39	sequence	sequence	NN
cord-350019-4nlbu54e	546	40	similarity	similarity	NN
cord-350019-4nlbu54e	546	41	between	between	IN
cord-350019-4nlbu54e	546	42	the	the	DT
cord-350019-4nlbu54e	546	43	Xist	Xist	NNP
cord-350019-4nlbu54e	546	44	and	and	CC
cord-350019-4nlbu54e	546	45	Rsx	Rsx	NNP
cord-350019-4nlbu54e	546	46	long	long	JJ
cord-350019-4nlbu54e	546	47	noncoding	noncoding	JJ
cord-350019-4nlbu54e	546	48	RNAs	rna	NNS
cord-350019-4nlbu54e	546	49	suggests	suggest	VBZ
cord-350019-4nlbu54e	546	50	shared	share	VBN
cord-350019-4nlbu54e	546	51	functions	function	NNS
cord-350019-4nlbu54e	546	52	of	of	IN
cord-350019-4nlbu54e	546	53	tandem	tandem	JJ
cord-350019-4nlbu54e	546	54	repeat	repeat	NN
cord-350019-4nlbu54e	546	55	domains	domain	NNS
cord-350019-4nlbu54e	546	56	Structural	structural	JJ
cord-350019-4nlbu54e	546	57	constraints	constraint	NNS
cord-350019-4nlbu54e	546	58	identified	identify	VBN
cord-350019-4nlbu54e	546	59	with	with	IN
cord-350019-4nlbu54e	546	60	covariation	covariation	NN
cord-350019-4nlbu54e	546	61	analysis	analysis	NN
cord-350019-4nlbu54e	546	62	in	in	IN
cord-350019-4nlbu54e	546	63	ribosomal	ribosomal	JJ
cord-350019-4nlbu54e	546	64	RNA	RNA	NNP
cord-350019-4nlbu54e	546	65	Covariation	Covariation	NNP
cord-350019-4nlbu54e	546	66	analysis	analysis	NN
cord-350019-4nlbu54e	546	67	with	with	IN
cord-350019-4nlbu54e	546	68	improved	improved	JJ
cord-350019-4nlbu54e	546	69	parameters	parameter	NNS
cord-350019-4nlbu54e	546	70	reveals	reveal	VBZ
cord-350019-4nlbu54e	546	71	conservation	conservation	NN
cord-350019-4nlbu54e	546	72	in	in	IN
cord-350019-4nlbu54e	546	73	lncRNA	lncrna	NN
cord-350019-4nlbu54e	546	74	structures	structure	NNS
cord-350019-4nlbu54e	547	1	The	the	DT
cord-350019-4nlbu54e	547	2	existence	existence	NN
cord-350019-4nlbu54e	547	3	of	of	IN
cord-350019-4nlbu54e	547	4	phylogenetic	phylogenetic	JJ
cord-350019-4nlbu54e	547	5	covariation	covariation	NN
cord-350019-4nlbu54e	547	6	in	in	IN
cord-350019-4nlbu54e	547	7	base	base	NN
cord-350019-4nlbu54e	547	8	-	-	HYPH
cord-350019-4nlbu54e	547	9	pairing	pairing	NN
cord-350019-4nlbu54e	547	10	is	be	VBZ
cord-350019-4nlbu54e	547	11	strong	strong	JJ
cord-350019-4nlbu54e	547	12	evidence	evidence	NN
cord-350019-4nlbu54e	547	13	for	for	IN
cord-350019-4nlbu54e	547	14	functional	functional	JJ
cord-350019-4nlbu54e	547	15	Dms	Dms	NNP
cord-350019-4nlbu54e	547	16	footprinting	footprinting	NN
cord-350019-4nlbu54e	547	17	of	of	IN
cord-350019-4nlbu54e	547	18	structured	structured	JJ
cord-350019-4nlbu54e	547	19	rnas	rnas	NNP
cord-350019-4nlbu54e	547	20	and	and	CC
cord-350019-4nlbu54e	547	21	rna	rna	NNP
cord-350019-4nlbu54e	547	22	-	-	HYPH
cord-350019-4nlbu54e	547	23	protein	protein	NN
cord-350019-4nlbu54e	547	24	complexes	complex	NNS
cord-350019-4nlbu54e	547	25	Dms	dms	VBP
cord-350019-4nlbu54e	547	26	footprinting	footprinting	NN
cord-350019-4nlbu54e	547	27	of	of	IN
cord-350019-4nlbu54e	547	28	structured	structured	JJ
cord-350019-4nlbu54e	547	29	rnas	rnas	NNP
cord-350019-4nlbu54e	547	30	and	and	CC
cord-350019-4nlbu54e	547	31	rna	rna	NNP
cord-350019-4nlbu54e	547	32	-	-	HYPH
cord-350019-4nlbu54e	547	33	protein	protein	NNP
cord-350019-4nlbu54e	547	34	complexes	complex	NNS
cord-350019-4nlbu54e	547	35	Genome	Genome	NNP
cord-350019-4nlbu54e	547	36	-	-	HYPH
cord-350019-4nlbu54e	547	37	wide	wide	JJ
cord-350019-4nlbu54e	547	38	probing	probing	NN
cord-350019-4nlbu54e	547	39	of	of	IN
cord-350019-4nlbu54e	547	40	RNA	RNA	NNP
cord-350019-4nlbu54e	547	41	structure	structure	NN
cord-350019-4nlbu54e	547	42	reveals	reveal	VBZ
cord-350019-4nlbu54e	547	43	active	active	JJ
cord-350019-4nlbu54e	547	44	unfolding	unfolding	NN
cord-350019-4nlbu54e	547	45	of	of	IN
cord-350019-4nlbu54e	547	46	mRNA	mRNA	NNP
cord-350019-4nlbu54e	547	47	structures	structure	NNS
cord-350019-4nlbu54e	547	48	in	in	IN
cord-350019-4nlbu54e	547	49	vivo	vivo	NN
cord-350019-4nlbu54e	547	50	Visualizing	visualize	VBG
cord-350019-4nlbu54e	547	51	the	the	DT
cord-350019-4nlbu54e	547	52	secondary	secondary	JJ
cord-350019-4nlbu54e	547	53	and	and	CC
cord-350019-4nlbu54e	547	54	tertiary	tertiary	JJ
cord-350019-4nlbu54e	547	55	architectural	architectural	JJ
cord-350019-4nlbu54e	547	56	domains	domain	NNS
cord-350019-4nlbu54e	547	57	of	of	IN
cord-350019-4nlbu54e	547	58	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	547	59	RepA	RepA	NNP
cord-350019-4nlbu54e	548	1	A	a	DT
cord-350019-4nlbu54e	548	2	G	g	NN
cord-350019-4nlbu54e	548	3	-	-	HYPH
cord-350019-4nlbu54e	548	4	rich	rich	JJ
cord-350019-4nlbu54e	548	5	motif	motif	NN
cord-350019-4nlbu54e	548	6	in	in	IN
cord-350019-4nlbu54e	548	7	the	the	DT
cord-350019-4nlbu54e	548	8	lncRNA	lncrna	NN
cord-350019-4nlbu54e	548	9	Braveheart	Braveheart	NNP
cord-350019-4nlbu54e	548	10	interacts	interact	VBZ
cord-350019-4nlbu54e	548	11	with	with	IN
cord-350019-4nlbu54e	548	12	a	a	DT
cord-350019-4nlbu54e	548	13	zinc	zinc	NN
cord-350019-4nlbu54e	548	14	-	-	HYPH
cord-350019-4nlbu54e	548	15	finger	finger	NN
cord-350019-4nlbu54e	548	16	transcription	transcription	NN
cord-350019-4nlbu54e	548	17	factor	factor	NN
cord-350019-4nlbu54e	548	18	to	to	TO
cord-350019-4nlbu54e	548	19	specify	specify	VB
cord-350019-4nlbu54e	548	20	the	the	DT
cord-350019-4nlbu54e	548	21	cardiovascular	cardiovascular	JJ
cord-350019-4nlbu54e	548	22	lineage	lineage	NN
cord-350019-4nlbu54e	548	23	Probing	probe	VBG
cord-350019-4nlbu54e	548	24	Xist	Xist	NNP
cord-350019-4nlbu54e	548	25	RNA	RNA	NNP
cord-350019-4nlbu54e	548	26	structure	structure	NN
cord-350019-4nlbu54e	548	27	in	in	IN
cord-350019-4nlbu54e	548	28	cells	cell	NNS
cord-350019-4nlbu54e	548	29	using	use	VBG
cord-350019-4nlbu54e	548	30	targeted	target	VBN
cord-350019-4nlbu54e	548	31	structure	structure	NN
cord-350019-4nlbu54e	548	32	-	-	HYPH
cord-350019-4nlbu54e	548	33	Seq	Seq	NNP
cord-350019-4nlbu54e	548	34	RNA	RNA	NNP
cord-350019-4nlbu54e	548	35	motif	motif	NN
cord-350019-4nlbu54e	548	36	discovery	discovery	NN
cord-350019-4nlbu54e	548	37	by	by	IN
cord-350019-4nlbu54e	548	38	SHAPE	shape	NN
cord-350019-4nlbu54e	548	39	and	and	CC
cord-350019-4nlbu54e	548	40	mutational	mutational	JJ
cord-350019-4nlbu54e	548	41	profiling	profiling	NN
cord-350019-4nlbu54e	548	42	(	(	-LRB-
cord-350019-4nlbu54e	548	43	SHAPE	shape	NN
cord-350019-4nlbu54e	548	44	-	-	HYPH
cord-350019-4nlbu54e	548	45	MaP	map	NN
cord-350019-4nlbu54e	548	46	)	)	-RRB-
cord-350019-4nlbu54e	549	1	Simultaneous	simultaneous	JJ
cord-350019-4nlbu54e	549	2	characterization	characterization	NN
cord-350019-4nlbu54e	549	3	of	of	IN
cord-350019-4nlbu54e	549	4	cellular	cellular	JJ
cord-350019-4nlbu54e	549	5	RNA	RNA	NNP
cord-350019-4nlbu54e	549	6	structure	structure	NN
cord-350019-4nlbu54e	549	7	and	and	CC
cord-350019-4nlbu54e	549	8	function	function	VB
cord-350019-4nlbu54e	549	9	with	with	IN
cord-350019-4nlbu54e	549	10	in	in	IN
cord-350019-4nlbu54e	549	11	-	-	HYPH
cord-350019-4nlbu54e	549	12	cell	cell	NN
cord-350019-4nlbu54e	549	13	SHAPE	shape	NN
cord-350019-4nlbu54e	549	14	-	-	HYPH
cord-350019-4nlbu54e	549	15	Seq	Seq	NNP
cord-350019-4nlbu54e	549	16	Transcriptome	Transcriptome	NNP
cord-350019-4nlbu54e	549	17	-	-	HYPH
cord-350019-4nlbu54e	549	18	wide	wide	JJ
cord-350019-4nlbu54e	549	19	interrogation	interrogation	NN
cord-350019-4nlbu54e	549	20	of	of	IN
cord-350019-4nlbu54e	549	21	RNA	RNA	NNP
cord-350019-4nlbu54e	549	22	secondary	secondary	JJ
cord-350019-4nlbu54e	549	23	structure	structure	NN
cord-350019-4nlbu54e	549	24	in	in	IN
cord-350019-4nlbu54e	549	25	living	live	VBG
cord-350019-4nlbu54e	549	26	cells	cell	NNS
cord-350019-4nlbu54e	549	27	with	with	IN
cord-350019-4nlbu54e	549	28	icSHAPE	icshape	NN
cord-350019-4nlbu54e	550	1	Exploring	explore	VBG
cord-350019-4nlbu54e	550	2	RNA	RNA	NNP
cord-350019-4nlbu54e	550	3	structural	structural	JJ
cord-350019-4nlbu54e	550	4	codes	code	NNS
cord-350019-4nlbu54e	550	5	with	with	IN
cord-350019-4nlbu54e	550	6	SHAPE	shape	NN
cord-350019-4nlbu54e	550	7	chemistry	chemistry	NN
cord-350019-4nlbu54e	551	1	Selective	selective	JJ
cord-350019-4nlbu54e	551	2	2′-hydroxyl	2′-hydroxyl	CD
cord-350019-4nlbu54e	551	3	acylation	acylation	NN
cord-350019-4nlbu54e	551	4	analyzed	analyze	VBN
cord-350019-4nlbu54e	551	5	by	by	IN
cord-350019-4nlbu54e	551	6	primer	primer	NN
cord-350019-4nlbu54e	551	7	extension	extension	NN
cord-350019-4nlbu54e	551	8	(	(	-LRB-
cord-350019-4nlbu54e	551	9	SHAPE	shape	NN
cord-350019-4nlbu54e	551	10	)	)	-RRB-
cord-350019-4nlbu54e	551	11	:	:	:
cord-350019-4nlbu54e	551	12	quantitative	quantitative	NNP
cord-350019-4nlbu54e	551	13	RNA	RNA	NNP
cord-350019-4nlbu54e	551	14	structure	structure	NN
cord-350019-4nlbu54e	551	15	analysis	analysis	NN
cord-350019-4nlbu54e	551	16	at	at	IN
cord-350019-4nlbu54e	551	17	single	single	JJ
cord-350019-4nlbu54e	551	18	nucleotide	nucleotide	JJ
cord-350019-4nlbu54e	551	19	resolution	resolution	NN
cord-350019-4nlbu54e	551	20	SHAPE	shape	NN
cord-350019-4nlbu54e	551	21	reveals	reveal	VBZ
cord-350019-4nlbu54e	551	22	transcript	transcript	NN
cord-350019-4nlbu54e	551	23	-	-	HYPH
cord-350019-4nlbu54e	551	24	wide	wide	JJ
cord-350019-4nlbu54e	551	25	interactions	interaction	NNS
cord-350019-4nlbu54e	551	26	,	,	,
cord-350019-4nlbu54e	551	27	complex	complex	JJ
cord-350019-4nlbu54e	551	28	structural	structural	JJ
cord-350019-4nlbu54e	551	29	domains	domain	NNS
cord-350019-4nlbu54e	551	30	,	,	,
cord-350019-4nlbu54e	551	31	and	and	CC
cord-350019-4nlbu54e	551	32	protein	protein	NN
cord-350019-4nlbu54e	551	33	interactions	interaction	NNS
cord-350019-4nlbu54e	551	34	across	across	IN
cord-350019-4nlbu54e	551	35	the	the	DT
cord-350019-4nlbu54e	551	36	Xist	Xist	NNP
cord-350019-4nlbu54e	551	37	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	551	38	in	in	IN
cord-350019-4nlbu54e	551	39	living	living	NN
cord-350019-4nlbu54e	551	40	cells	cell	NNS
cord-350019-4nlbu54e	551	41	Comparison	comparison	NN
cord-350019-4nlbu54e	551	42	of	of	IN
cord-350019-4nlbu54e	551	43	SHAPE	shape	NN
cord-350019-4nlbu54e	551	44	reagents	reagent	NNS
cord-350019-4nlbu54e	551	45	for	for	IN
cord-350019-4nlbu54e	551	46	mapping	map	VBG
cord-350019-4nlbu54e	551	47	RNA	RNA	NNP
cord-350019-4nlbu54e	551	48	structures	structure	NNS
cord-350019-4nlbu54e	551	49	inside	inside	IN
cord-350019-4nlbu54e	551	50	living	living	NN
cord-350019-4nlbu54e	551	51	cells	cell	NNS
cord-350019-4nlbu54e	552	1	Tandem	tandem	JJ
cord-350019-4nlbu54e	552	2	stem	stem	NN
cord-350019-4nlbu54e	552	3	-	-	HYPH
cord-350019-4nlbu54e	552	4	loops	loop	NNS
cord-350019-4nlbu54e	552	5	in	in	IN
cord-350019-4nlbu54e	552	6	roX	rox	JJ
cord-350019-4nlbu54e	552	7	RNAs	rna	NNS
cord-350019-4nlbu54e	552	8	act	act	VBP
cord-350019-4nlbu54e	552	9	together	together	RB
cord-350019-4nlbu54e	552	10	to	to	TO
cord-350019-4nlbu54e	552	11	mediate	mediate	VB
cord-350019-4nlbu54e	552	12	X	x	NN
cord-350019-4nlbu54e	552	13	chromosome	chromosome	NN
cord-350019-4nlbu54e	552	14	dosage	dosage	NN
cord-350019-4nlbu54e	552	15	compensation	compensation	NN
cord-350019-4nlbu54e	552	16	in	in	IN
cord-350019-4nlbu54e	552	17	Drosophila	Drosophila	NNP
cord-350019-4nlbu54e	552	18	RNA	RNA	NNP
cord-350019-4nlbu54e	552	19	duplex	duplex	NN
cord-350019-4nlbu54e	552	20	map	map	NN
cord-350019-4nlbu54e	552	21	in	in	IN
cord-350019-4nlbu54e	552	22	living	living	NN
cord-350019-4nlbu54e	552	23	cells	cell	NNS
cord-350019-4nlbu54e	552	24	reveals	reveal	VBZ
cord-350019-4nlbu54e	552	25	higher	high	JJR
cord-350019-4nlbu54e	552	26	-	-	HYPH
cord-350019-4nlbu54e	552	27	order	order	NN
cord-350019-4nlbu54e	552	28	transcriptome	transcriptome	NN
cord-350019-4nlbu54e	552	29	structure	structure	NN
cord-350019-4nlbu54e	552	30	Function	Function	NNP
cord-350019-4nlbu54e	552	31	of	of	IN
cord-350019-4nlbu54e	552	32	alternative	alternative	JJ
cord-350019-4nlbu54e	552	33	splicing	splice	VBG
cord-350019-4nlbu54e	552	34	Comprehensive	comprehensive	JJ
cord-350019-4nlbu54e	552	35	network	network	NN
cord-350019-4nlbu54e	552	36	analysis	analysis	NN
cord-350019-4nlbu54e	552	37	reveals	reveal	VBZ
cord-350019-4nlbu54e	552	38	alternative	alternative	JJ
cord-350019-4nlbu54e	552	39	splicing	splicing	NN
cord-350019-4nlbu54e	552	40	-	-	HYPH
cord-350019-4nlbu54e	552	41	related	relate	VBN
cord-350019-4nlbu54e	552	42	lncRNAs	lncRNAs	NNP
cord-350019-4nlbu54e	552	43	in	in	IN
cord-350019-4nlbu54e	552	44	hepatocellular	hepatocellular	JJ
cord-350019-4nlbu54e	552	45	carcinoma	carcinoma	NN
cord-350019-4nlbu54e	552	46	A	a	DT
cord-350019-4nlbu54e	552	47	genomic	genomic	JJ
cord-350019-4nlbu54e	552	48	view	view	NN
cord-350019-4nlbu54e	552	49	of	of	IN
cord-350019-4nlbu54e	552	50	alternative	alternative	JJ
cord-350019-4nlbu54e	552	51	splicing	splicing	NN
cord-350019-4nlbu54e	552	52	of	of	IN
cord-350019-4nlbu54e	552	53	long	long	JJ
cord-350019-4nlbu54e	552	54	non	non	JJ
cord-350019-4nlbu54e	552	55	-	-	JJ
cord-350019-4nlbu54e	552	56	coding	coding	JJ
cord-350019-4nlbu54e	552	57	RNAs	rna	NNS
cord-350019-4nlbu54e	552	58	during	during	IN
cord-350019-4nlbu54e	552	59	rice	rice	NN
cord-350019-4nlbu54e	552	60	seed	seed	NN
cord-350019-4nlbu54e	552	61	development	development	NN
cord-350019-4nlbu54e	552	62	reveals	reveal	VBZ
cord-350019-4nlbu54e	552	63	extensive	extensive	JJ
cord-350019-4nlbu54e	552	64	splicing	splicing	NN
cord-350019-4nlbu54e	552	65	and	and	CC
cord-350019-4nlbu54e	552	66	lncRNA	lncrna	NN
cord-350019-4nlbu54e	552	67	gene	gene	NN
cord-350019-4nlbu54e	552	68	families	family	NNS
cord-350019-4nlbu54e	553	1	The	the	DT
cord-350019-4nlbu54e	553	2	more	more	RBR
cord-350019-4nlbu54e	553	3	the	the	DT
cord-350019-4nlbu54e	553	4	merrier	merry	JJR
cord-350019-4nlbu54e	553	5	-	-	HYPH
cord-350019-4nlbu54e	553	6	complexity	complexity	NN
cord-350019-4nlbu54e	553	7	in	in	IN
cord-350019-4nlbu54e	553	8	long	long	JJ
cord-350019-4nlbu54e	553	9	non	non	JJ
cord-350019-4nlbu54e	553	10	-	-	JJ
cord-350019-4nlbu54e	553	11	coding	coding	JJ
cord-350019-4nlbu54e	553	12	RNA	RNA	NNP
cord-350019-4nlbu54e	553	13	loci	locus	NNS
cord-350019-4nlbu54e	553	14	Analysis	Analysis	NNP
cord-350019-4nlbu54e	553	15	and	and	CC
cord-350019-4nlbu54e	553	16	design	design	NN
cord-350019-4nlbu54e	553	17	of	of	IN
cord-350019-4nlbu54e	553	18	RNA	RNA	NNP
cord-350019-4nlbu54e	553	19	sequencing	sequencing	NN
cord-350019-4nlbu54e	553	20	experiments	experiment	NNS
cord-350019-4nlbu54e	553	21	for	for	IN
cord-350019-4nlbu54e	553	22	identifying	identify	VBG
cord-350019-4nlbu54e	553	23	isoform	isoform	NN
cord-350019-4nlbu54e	553	24	regulation	regulation	NN
cord-350019-4nlbu54e	553	25	Conservation	Conservation	NNP
cord-350019-4nlbu54e	553	26	of	of	IN
cord-350019-4nlbu54e	553	27	an	an	DT
cord-350019-4nlbu54e	553	28	RNA	RNA	NNP
cord-350019-4nlbu54e	553	29	regulatory	regulatory	JJ
cord-350019-4nlbu54e	553	30	map	map	NN
cord-350019-4nlbu54e	553	31	between	between	IN
cord-350019-4nlbu54e	553	32	Drosophila	Drosophila	NNP
cord-350019-4nlbu54e	553	33	and	and	CC
cord-350019-4nlbu54e	553	34	mammals	mammal	NNS
cord-350019-4nlbu54e	553	35	MAJIQ	MAJIQ	NNP
cord-350019-4nlbu54e	553	36	-	-	HYPH
cord-350019-4nlbu54e	553	37	SPEL	SPEL	NNP
cord-350019-4nlbu54e	553	38	:	:	:
cord-350019-4nlbu54e	553	39	web	web	NN
cord-350019-4nlbu54e	553	40	-	-	HYPH
cord-350019-4nlbu54e	553	41	tool	tool	NN
cord-350019-4nlbu54e	553	42	to	to	TO
cord-350019-4nlbu54e	553	43	interrogate	interrogate	VB
cord-350019-4nlbu54e	553	44	classical	classical	JJ
cord-350019-4nlbu54e	553	45	and	and	CC
cord-350019-4nlbu54e	553	46	complex	complex	JJ
cord-350019-4nlbu54e	553	47	splicing	splicing	NN
cord-350019-4nlbu54e	553	48	variations	variation	NNS
cord-350019-4nlbu54e	553	49	from	from	IN
cord-350019-4nlbu54e	553	50	RNA	RNA	NNP
cord-350019-4nlbu54e	553	51	-	-	HYPH
cord-350019-4nlbu54e	553	52	Seq	Seq	NNP
cord-350019-4nlbu54e	553	53	data	data	NN
cord-350019-4nlbu54e	553	54	DRIMSeq	drimseq	NN
cord-350019-4nlbu54e	553	55	:	:	:
cord-350019-4nlbu54e	553	56	a	a	DT
cord-350019-4nlbu54e	553	57	Dirichlet	dirichlet	JJ
cord-350019-4nlbu54e	553	58	-	-	HYPH
cord-350019-4nlbu54e	553	59	multinomial	multinomial	JJ
cord-350019-4nlbu54e	553	60	framework	framework	NN
cord-350019-4nlbu54e	553	61	for	for	IN
cord-350019-4nlbu54e	553	62	multivariate	multivariate	JJ
cord-350019-4nlbu54e	553	63	count	count	NN
cord-350019-4nlbu54e	553	64	outcomes	outcome	NNS
cord-350019-4nlbu54e	553	65	in	in	IN
cord-350019-4nlbu54e	553	66	genomics	genomic	NNS
cord-350019-4nlbu54e	553	67	TransRate	TransRate	NNP
cord-350019-4nlbu54e	553	68	:	:	:
cord-350019-4nlbu54e	553	69	reference	reference	NN
cord-350019-4nlbu54e	553	70	-	-	HYPH
cord-350019-4nlbu54e	553	71	free	free	JJ
cord-350019-4nlbu54e	553	72	quality	quality	NN
cord-350019-4nlbu54e	553	73	assessment	assessment	NN
cord-350019-4nlbu54e	553	74	of	of	IN
cord-350019-4nlbu54e	553	75	de	de	NNP
cord-350019-4nlbu54e	553	76	novo	novo	NNP
cord-350019-4nlbu54e	553	77	transcriptome	transcriptome	NNP
cord-350019-4nlbu54e	553	78	assemblies	assembly	NNS
cord-350019-4nlbu54e	553	79	De	De	NNP
cord-350019-4nlbu54e	553	80	novo	novo	NNP
cord-350019-4nlbu54e	553	81	prediction	prediction	NN
cord-350019-4nlbu54e	553	82	of	of	IN
cord-350019-4nlbu54e	553	83	stem	stem	NN
cord-350019-4nlbu54e	553	84	cell	cell	NN
cord-350019-4nlbu54e	553	85	identity	identity	NN
cord-350019-4nlbu54e	553	86	using	use	VBG
cord-350019-4nlbu54e	553	87	single	single	JJ
cord-350019-4nlbu54e	553	88	-	-	HYPH
cord-350019-4nlbu54e	553	89	cell	cell	NN
cord-350019-4nlbu54e	553	90	transcriptome	transcriptome	NN
cord-350019-4nlbu54e	553	91	data	datum	NNS
cord-350019-4nlbu54e	553	92	Bridger	Bridger	NNP
cord-350019-4nlbu54e	553	93	:	:	:
cord-350019-4nlbu54e	553	94	a	a	DT
cord-350019-4nlbu54e	553	95	new	new	JJ
cord-350019-4nlbu54e	553	96	framework	framework	NN
cord-350019-4nlbu54e	553	97	for	for	IN
cord-350019-4nlbu54e	553	98	de	de	NNP
cord-350019-4nlbu54e	553	99	novo	novo	NNP
cord-350019-4nlbu54e	553	100	transcriptome	transcriptome	NNP
cord-350019-4nlbu54e	553	101	assembly	assembly	NNP
cord-350019-4nlbu54e	553	102	using	use	VBG
cord-350019-4nlbu54e	553	103	RNA	RNA	NNP
cord-350019-4nlbu54e	553	104	-	-	HYPH
cord-350019-4nlbu54e	553	105	seq	seq	NNP
cord-350019-4nlbu54e	553	106	data	data	NN
cord-350019-4nlbu54e	553	107	Comprehensive	comprehensive	JJ
cord-350019-4nlbu54e	553	108	comparison	comparison	NN
cord-350019-4nlbu54e	553	109	of	of	IN
cord-350019-4nlbu54e	553	110	Pacific	Pacific	NNP
cord-350019-4nlbu54e	553	111	Biosciences	Biosciences	NNPS
cord-350019-4nlbu54e	553	112	and	and	CC
cord-350019-4nlbu54e	553	113	Oxford	Oxford	NNP
cord-350019-4nlbu54e	553	114	Nanopore	Nanopore	NNP
cord-350019-4nlbu54e	553	115	Technologies	Technologies	NNPS
cord-350019-4nlbu54e	553	116	and	and	CC
cord-350019-4nlbu54e	553	117	their	-PRON-	PRP$
cord-350019-4nlbu54e	553	118	applications	application	NNS
cord-350019-4nlbu54e	553	119	to	to	IN
cord-350019-4nlbu54e	553	120	transcriptome	transcriptome	NN
cord-350019-4nlbu54e	553	121	analysis	analysis	NN
cord-350019-4nlbu54e	554	1	Relative	relative	JJ
cord-350019-4nlbu54e	554	2	performances	performance	NNS
cord-350019-4nlbu54e	554	3	of	of	IN
cord-350019-4nlbu54e	554	4	Oxford	Oxford	NNP
cord-350019-4nlbu54e	554	5	Nanopore	Nanopore	NNP
cord-350019-4nlbu54e	554	6	MinION	MinION	NNP
cord-350019-4nlbu54e	554	7	vs.	vs.	IN
cord-350019-4nlbu54e	554	8	Pacific	Pacific	NNP
cord-350019-4nlbu54e	554	9	Biosciences	Biosciences	NNPS
cord-350019-4nlbu54e	555	1	Sequel	Sequel	VBN
cord-350019-4nlbu54e	555	2	third	third	JJ
cord-350019-4nlbu54e	555	3	-	-	HYPH
cord-350019-4nlbu54e	555	4	generation	generation	NN
cord-350019-4nlbu54e	555	5	sequencing	sequencing	NN
cord-350019-4nlbu54e	555	6	platforms	platform	NNS
cord-350019-4nlbu54e	555	7	in	in	IN
cord-350019-4nlbu54e	555	8	identification	identification	NN
cord-350019-4nlbu54e	555	9	of	of	IN
cord-350019-4nlbu54e	555	10	agricultural	agricultural	JJ
cord-350019-4nlbu54e	555	11	and	and	CC
cord-350019-4nlbu54e	555	12	forest	forest	NN
cord-350019-4nlbu54e	555	13	pathogens	pathogen	NNS
cord-350019-4nlbu54e	555	14	PacBio	PacBio	NNP
cord-350019-4nlbu54e	555	15	sequencing	sequencing	NN
cord-350019-4nlbu54e	555	16	and	and	CC
cord-350019-4nlbu54e	555	17	its	-PRON-	PRP$
cord-350019-4nlbu54e	555	18	applications	application	NNS
cord-350019-4nlbu54e	556	1	An	an	DT
cord-350019-4nlbu54e	556	2	evaluation	evaluation	NN
cord-350019-4nlbu54e	556	3	of	of	IN
cord-350019-4nlbu54e	556	4	the	the	DT
cord-350019-4nlbu54e	556	5	PacBio	PacBio	NNP
cord-350019-4nlbu54e	556	6	RS	rs	NN
cord-350019-4nlbu54e	556	7	platform	platform	NN
cord-350019-4nlbu54e	556	8	for	for	IN
cord-350019-4nlbu54e	556	9	sequencing	sequencing	NN
cord-350019-4nlbu54e	556	10	and	and	CC
cord-350019-4nlbu54e	556	11	de	de	NNP
cord-350019-4nlbu54e	556	12	novo	novo	NNP
cord-350019-4nlbu54e	556	13	assembly	assembly	NNP
cord-350019-4nlbu54e	556	14	of	of	IN
cord-350019-4nlbu54e	556	15	a	a	DT
cord-350019-4nlbu54e	556	16	chloroplast	chloroplast	NN
cord-350019-4nlbu54e	556	17	genome	genome	NN
cord-350019-4nlbu54e	556	18	NanoPack	NanoPack	NNP
cord-350019-4nlbu54e	556	19	:	:	:
cord-350019-4nlbu54e	556	20	visualizing	visualize	VBG
cord-350019-4nlbu54e	556	21	and	and	CC
cord-350019-4nlbu54e	556	22	processing	process	VBG
cord-350019-4nlbu54e	556	23	long	long	RB
cord-350019-4nlbu54e	556	24	-	-	HYPH
cord-350019-4nlbu54e	556	25	read	read	VBN
cord-350019-4nlbu54e	556	26	sequencing	sequencing	NN
cord-350019-4nlbu54e	556	27	data	datum	NNS
cord-350019-4nlbu54e	556	28	RNA	RNA	NNP
cord-350019-4nlbu54e	556	29	and	and	CC
cord-350019-4nlbu54e	556	30	gene	gene	NN
cord-350019-4nlbu54e	556	31	expression	expression	NN
cord-350019-4nlbu54e	556	32	analysis	analysis	NN
cord-350019-4nlbu54e	556	33	using	use	VBG
cord-350019-4nlbu54e	556	34	direct	direct	JJ
cord-350019-4nlbu54e	556	35	RNA	RNA	NNP
cord-350019-4nlbu54e	556	36	and	and	CC
cord-350019-4nlbu54e	556	37	cDNA	cdna	NN
cord-350019-4nlbu54e	556	38	sequencing	sequencing	NN
cord-350019-4nlbu54e	556	39	Improving	improve	VBG
cord-350019-4nlbu54e	556	40	nanopore	nanopore	NNP
cord-350019-4nlbu54e	556	41	read	read	VBD
cord-350019-4nlbu54e	556	42	accuracy	accuracy	NN
cord-350019-4nlbu54e	556	43	with	with	IN
cord-350019-4nlbu54e	556	44	the	the	DT
cord-350019-4nlbu54e	556	45	R2C2	R2C2	NNP
cord-350019-4nlbu54e	556	46	method	method	NN
cord-350019-4nlbu54e	556	47	enables	enable	VBZ
cord-350019-4nlbu54e	556	48	the	the	DT
cord-350019-4nlbu54e	556	49	sequencing	sequencing	NN
cord-350019-4nlbu54e	556	50	of	of	IN
cord-350019-4nlbu54e	556	51	highly	highly	RB
cord-350019-4nlbu54e	556	52	multiplexed	multiplexed	JJ
cord-350019-4nlbu54e	556	53	full	full	JJ
cord-350019-4nlbu54e	556	54	-	-	HYPH
cord-350019-4nlbu54e	556	55	length	length	NN
cord-350019-4nlbu54e	556	56	single	single	JJ
cord-350019-4nlbu54e	556	57	-	-	HYPH
cord-350019-4nlbu54e	556	58	cell	cell	NN
cord-350019-4nlbu54e	556	59	cDNA	cdna	NN
cord-350019-4nlbu54e	556	60	Transcriptome	Transcriptome	NNP
cord-350019-4nlbu54e	556	61	-	-	HYPH
cord-350019-4nlbu54e	556	62	wide	wide	JJ
cord-350019-4nlbu54e	556	63	analysis	analysis	NN
cord-350019-4nlbu54e	556	64	of	of	IN
cord-350019-4nlbu54e	556	65	a	a	DT
cord-350019-4nlbu54e	556	66	baculovirus	baculovirus	NN
cord-350019-4nlbu54e	556	67	using	use	VBG
cord-350019-4nlbu54e	556	68	nanopore	nanopore	NNP
cord-350019-4nlbu54e	556	69	sequencing	sequence	VBG
cord-350019-4nlbu54e	556	70	Native	native	JJ
cord-350019-4nlbu54e	556	71	molecule	molecule	NN
cord-350019-4nlbu54e	556	72	sequencing	sequencing	NN
cord-350019-4nlbu54e	556	73	by	by	IN
cord-350019-4nlbu54e	556	74	nano	nano	NNP
cord-350019-4nlbu54e	556	75	-	-	HYPH
cord-350019-4nlbu54e	556	76	ID	ID	NNP
cord-350019-4nlbu54e	556	77	reveals	reveal	VBZ
cord-350019-4nlbu54e	556	78	synthesis	synthesis	NN
cord-350019-4nlbu54e	556	79	and	and	CC
cord-350019-4nlbu54e	556	80	stability	stability	NN
cord-350019-4nlbu54e	556	81	of	of	IN
cord-350019-4nlbu54e	556	82	RNA	RNA	NNP
cord-350019-4nlbu54e	556	83	isoforms	isoform	NNS
cord-350019-4nlbu54e	556	84	Transcriptome	Transcriptome	NNP
cord-350019-4nlbu54e	556	85	profiling	profile	VBG
cord-350019-4nlbu54e	556	86	using	use	VBG
cord-350019-4nlbu54e	556	87	single	single	JJ
cord-350019-4nlbu54e	556	88	-	-	HYPH
cord-350019-4nlbu54e	556	89	molecule	molecule	NN
cord-350019-4nlbu54e	556	90	direct	direct	JJ
cord-350019-4nlbu54e	556	91	RNA	RNA	NNP
cord-350019-4nlbu54e	556	92	sequencing	sequencing	NN
cord-350019-4nlbu54e	556	93	approach	approach	NN
cord-350019-4nlbu54e	556	94	for	for	IN
cord-350019-4nlbu54e	556	95	in	in	IN
cord-350019-4nlbu54e	556	96	-	-	HYPH
cord-350019-4nlbu54e	556	97	depth	depth	NN
cord-350019-4nlbu54e	556	98	understanding	understanding	NN
cord-350019-4nlbu54e	556	99	of	of	IN
cord-350019-4nlbu54e	556	100	genes	gene	NNS
cord-350019-4nlbu54e	556	101	in	in	IN
cord-350019-4nlbu54e	556	102	secondary	secondary	JJ
cord-350019-4nlbu54e	556	103	metabolism	metabolism	NN
cord-350019-4nlbu54e	556	104	pathways	pathway	NNS
cord-350019-4nlbu54e	556	105	of	of	IN
cord-350019-4nlbu54e	556	106	Camellia	Camellia	NNP
cord-350019-4nlbu54e	556	107	sinensis	sinensis	NN
cord-350019-4nlbu54e	556	108	Structural	structural	JJ
cord-350019-4nlbu54e	556	109	analyses	analysis	NNS
cord-350019-4nlbu54e	556	110	of	of	IN
cord-350019-4nlbu54e	556	111	NEAT1	NEAT1	NNP
cord-350019-4nlbu54e	557	1	lncRNAs	lncrnas	RB
cord-350019-4nlbu54e	557	2	suggest	suggest	VBP
cord-350019-4nlbu54e	557	3	long	long	JJ
cord-350019-4nlbu54e	557	4	-	-	HYPH
cord-350019-4nlbu54e	557	5	range	range	NN
cord-350019-4nlbu54e	557	6	RNA	RNA	NNP
cord-350019-4nlbu54e	557	7	interactions	interaction	NNS
cord-350019-4nlbu54e	557	8	that	that	WDT
cord-350019-4nlbu54e	557	9	may	may	MD
cord-350019-4nlbu54e	557	10	contribute	contribute	VB
cord-350019-4nlbu54e	557	11	to	to	IN
cord-350019-4nlbu54e	557	12	paraspeckle	paraspeckle	NN
cord-350019-4nlbu54e	557	13	architecture	architecture	NN
cord-350019-4nlbu54e	558	1	The	the	DT
cord-350019-4nlbu54e	558	2	MBNL3	MBNL3	NNS
cord-350019-4nlbu54e	558	3	splicing	splicing	NN
cord-350019-4nlbu54e	558	4	factor	factor	NN
cord-350019-4nlbu54e	558	5	promotes	promote	VBZ
cord-350019-4nlbu54e	558	6	hepatocellular	hepatocellular	JJ
cord-350019-4nlbu54e	558	7	carcinoma	carcinoma	NN
cord-350019-4nlbu54e	558	8	by	by	IN
cord-350019-4nlbu54e	558	9	increasing	increase	VBG
cord-350019-4nlbu54e	558	10	PXN	PXN	NNP
cord-350019-4nlbu54e	558	11	expression	expression	NN
cord-350019-4nlbu54e	558	12	through	through	IN
cord-350019-4nlbu54e	558	13	the	the	DT
cord-350019-4nlbu54e	558	14	alternative	alternative	JJ
cord-350019-4nlbu54e	558	15	splicing	splicing	NN
cord-350019-4nlbu54e	558	16	of	of	IN
cord-350019-4nlbu54e	558	17	lncRNA	lncRNA	NNP
cord-350019-4nlbu54e	558	18	-	-	HYPH
cord-350019-4nlbu54e	558	19	PXN	PXN	NNP
cord-350019-4nlbu54e	558	20	-	-	HYPH
cord-350019-4nlbu54e	558	21	AS1	AS1	NNP
cord-350019-4nlbu54e	558	22	A	a	DT
cord-350019-4nlbu54e	558	23	majority	majority	NN
cord-350019-4nlbu54e	558	24	of	of	IN
cord-350019-4nlbu54e	558	25	m6A	m6a	NN
cord-350019-4nlbu54e	558	26	residues	residue	NNS
cord-350019-4nlbu54e	558	27	are	be	VBP
cord-350019-4nlbu54e	558	28	in	in	IN
cord-350019-4nlbu54e	558	29	the	the	DT
cord-350019-4nlbu54e	558	30	last	last	JJ
cord-350019-4nlbu54e	558	31	exons	exon	NNS
cord-350019-4nlbu54e	558	32	,	,	,
cord-350019-4nlbu54e	558	33	allowing	allow	VBG
cord-350019-4nlbu54e	558	34	the	the	DT
cord-350019-4nlbu54e	558	35	potential	potential	NN
cord-350019-4nlbu54e	558	36	for	for	IN
cord-350019-4nlbu54e	558	37	3′	3′	CD
cord-350019-4nlbu54e	558	38	UTR	UTR	NNP
cord-350019-4nlbu54e	558	39	regulation	regulation	NN
cord-350019-4nlbu54e	558	40	Probing	Probing	NNP
cord-350019-4nlbu54e	558	41	N6-methyladenosine	n6-methyladenosine	CC
cord-350019-4nlbu54e	558	42	RNA	RNA	NNP
cord-350019-4nlbu54e	558	43	modification	modification	NN
cord-350019-4nlbu54e	558	44	status	status	NN
cord-350019-4nlbu54e	558	45	at	at	IN
cord-350019-4nlbu54e	558	46	single	single	JJ
cord-350019-4nlbu54e	558	47	nucleotide	nucleotide	JJ
cord-350019-4nlbu54e	558	48	resolution	resolution	NN
cord-350019-4nlbu54e	558	49	in	in	IN
cord-350019-4nlbu54e	558	50	mRNA	mRNA	NNP
cord-350019-4nlbu54e	558	51	and	and	CC
cord-350019-4nlbu54e	558	52	long	long	JJ
cord-350019-4nlbu54e	558	53	noncoding	noncoding	JJ
cord-350019-4nlbu54e	558	54	RNA	RNA	NNP
cord-350019-4nlbu54e	558	55	m6A	m6A	NNP
cord-350019-4nlbu54e	558	56	modification	modification	NN
cord-350019-4nlbu54e	558	57	controls	control	VBZ
cord-350019-4nlbu54e	558	58	the	the	DT
cord-350019-4nlbu54e	558	59	innate	innate	JJ
cord-350019-4nlbu54e	558	60	immune	immune	JJ
cord-350019-4nlbu54e	558	61	response	response	NN
cord-350019-4nlbu54e	558	62	to	to	IN
cord-350019-4nlbu54e	558	63	infection	infection	NN
cord-350019-4nlbu54e	558	64	by	by	IN
cord-350019-4nlbu54e	558	65	targeting	target	VBG
cord-350019-4nlbu54e	558	66	type	type	NN
cord-350019-4nlbu54e	559	1	I	-PRON-	PRP
cord-350019-4nlbu54e	559	2	interferons	interferon	NNS
cord-350019-4nlbu54e	560	1	N(6)-methyladenosine	n(6)-methyladenosine	JJ
cord-350019-4nlbu54e	560	2	modification	modification	NN
cord-350019-4nlbu54e	560	3	in	in	IN
cord-350019-4nlbu54e	560	4	a	a	DT
cord-350019-4nlbu54e	560	5	long	long	JJ
cord-350019-4nlbu54e	560	6	noncoding	noncoding	JJ
cord-350019-4nlbu54e	560	7	RNA	RNA	NNP
cord-350019-4nlbu54e	560	8	hairpin	hairpin	NN
cord-350019-4nlbu54e	560	9	predisposes	predispose	VBZ
cord-350019-4nlbu54e	560	10	its	-PRON-	PRP$
cord-350019-4nlbu54e	560	11	conformation	conformation	NN
cord-350019-4nlbu54e	560	12	to	to	IN
cord-350019-4nlbu54e	560	13	protein	protein	NN
cord-350019-4nlbu54e	560	14	binding	bind	VBG
cord-350019-4nlbu54e	560	15	m6A	m6a	NN
cord-350019-4nlbu54e	560	16	modification	modification	NN
cord-350019-4nlbu54e	560	17	of	of	IN
cord-350019-4nlbu54e	560	18	non	non	JJ
cord-350019-4nlbu54e	560	19	-	-	JJ
cord-350019-4nlbu54e	560	20	coding	coding	JJ
cord-350019-4nlbu54e	560	21	RNA	RNA	NNP
cord-350019-4nlbu54e	560	22	and	and	CC
cord-350019-4nlbu54e	560	23	the	the	DT
cord-350019-4nlbu54e	560	24	control	control	NN
cord-350019-4nlbu54e	560	25	of	of	IN
cord-350019-4nlbu54e	560	26	mammalian	mammalian	JJ
cord-350019-4nlbu54e	560	27	gene	gene	NN
cord-350019-4nlbu54e	560	28	expression	expression	NN
cord-350019-4nlbu54e	560	29	Topology	topology	NN
cord-350019-4nlbu54e	560	30	of	of	IN
cord-350019-4nlbu54e	560	31	the	the	DT
cord-350019-4nlbu54e	560	32	human	human	NN
cord-350019-4nlbu54e	560	33	and	and	CC
cord-350019-4nlbu54e	560	34	mouse	mouse	NN
cord-350019-4nlbu54e	560	35	m6A	m6A	NNP
cord-350019-4nlbu54e	560	36	RNA	RNA	NNP
cord-350019-4nlbu54e	560	37	methylomes	methylome	NNS
cord-350019-4nlbu54e	560	38	revealed	reveal	VBN
cord-350019-4nlbu54e	560	39	by	by	IN
cord-350019-4nlbu54e	560	40	m6A	m6A	NNP
cord-350019-4nlbu54e	560	41	-	-	HYPH
cord-350019-4nlbu54e	560	42	seq	seq	NNP
cord-350019-4nlbu54e	560	43	Comprehensive	Comprehensive	NNP
cord-350019-4nlbu54e	560	44	analysis	analysis	NN
cord-350019-4nlbu54e	560	45	of	of	IN
cord-350019-4nlbu54e	560	46	mRNA	mRNA	NNP
cord-350019-4nlbu54e	560	47	methylation	methylation	NNP
cord-350019-4nlbu54e	561	1	reveals	reveal	VBZ
cord-350019-4nlbu54e	561	2	enrichment	enrichment	NN
cord-350019-4nlbu54e	561	3	in	in	IN
cord-350019-4nlbu54e	561	4	3′	3′	CD
cord-350019-4nlbu54e	561	5	UTRs	utr	NNS
cord-350019-4nlbu54e	561	6	and	and	CC
cord-350019-4nlbu54e	562	1	near	near	IN
cord-350019-4nlbu54e	562	2	stop	stop	NNP
cord-350019-4nlbu54e	562	3	codons	codon	NNS
cord-350019-4nlbu54e	562	4	M	M	NNP
cord-350019-4nlbu54e	562	5	6	6	CD
cord-350019-4nlbu54e	562	6	A	A	NNP
cord-350019-4nlbu54e	562	7	-	-	HYPH
cord-350019-4nlbu54e	562	8	induced	induce	VBN
cord-350019-4nlbu54e	562	9	lncRNA	lncrna	NN
cord-350019-4nlbu54e	562	10	RP11	RP11	NNP
cord-350019-4nlbu54e	562	11	triggers	trigger	VBZ
cord-350019-4nlbu54e	562	12	the	the	DT
cord-350019-4nlbu54e	562	13	dissemination	dissemination	NN
cord-350019-4nlbu54e	562	14	of	of	IN
cord-350019-4nlbu54e	562	15	colorectal	colorectal	JJ
cord-350019-4nlbu54e	562	16	cancer	cancer	NN
cord-350019-4nlbu54e	562	17	cells	cell	NNS
cord-350019-4nlbu54e	562	18	via	via	IN
cord-350019-4nlbu54e	562	19	upregulation	upregulation	NN
cord-350019-4nlbu54e	562	20	of	of	IN
cord-350019-4nlbu54e	562	21	Zeb1	Zeb1	NNP
cord-350019-4nlbu54e	562	22	MODOMICS	MODOMICS	NNP
cord-350019-4nlbu54e	562	23	:	:	:
cord-350019-4nlbu54e	562	24	a	a	DT
cord-350019-4nlbu54e	562	25	database	database	NN
cord-350019-4nlbu54e	562	26	of	of	IN
cord-350019-4nlbu54e	562	27	RNA	RNA	NNP
cord-350019-4nlbu54e	562	28	modification	modification	NN
cord-350019-4nlbu54e	562	29	pathways	pathway	NNS
cord-350019-4nlbu54e	562	30	.	.	.
cord-350019-4nlbu54e	563	1	2017	2017	CD
cord-350019-4nlbu54e	563	2	update	update	NN
cord-350019-4nlbu54e	563	3	Detecting	detect	VBG
cord-350019-4nlbu54e	563	4	RNA	RNA	NNP
cord-350019-4nlbu54e	563	5	modifications	modification	NNS
cord-350019-4nlbu54e	563	6	in	in	IN
cord-350019-4nlbu54e	563	7	the	the	DT
cord-350019-4nlbu54e	563	8	epitranscriptome	epitranscriptome	NN
cord-350019-4nlbu54e	563	9	:	:	:
cord-350019-4nlbu54e	563	10	predict	predict	VB
cord-350019-4nlbu54e	563	11	and	and	CC
cord-350019-4nlbu54e	563	12	validate	validate	VB
cord-350019-4nlbu54e	563	13	Accurate	accurate	JJ
cord-350019-4nlbu54e	563	14	detection	detection	NN
cord-350019-4nlbu54e	563	15	of	of	IN
cord-350019-4nlbu54e	563	16	m6A	m6A	NNP
cord-350019-4nlbu54e	563	17	RNA	RNA	NNP
cord-350019-4nlbu54e	563	18	modifications	modification	NNS
cord-350019-4nlbu54e	563	19	in	in	IN
cord-350019-4nlbu54e	563	20	native	native	JJ
cord-350019-4nlbu54e	563	21	RNA	RNA	NNP
cord-350019-4nlbu54e	563	22	sequences	sequence	NNS
cord-350019-4nlbu54e	564	1	A	a	DT
cord-350019-4nlbu54e	564	2	gene	gene	NN
cord-350019-4nlbu54e	564	3	from	from	IN
cord-350019-4nlbu54e	564	4	the	the	DT
cord-350019-4nlbu54e	564	5	region	region	NN
cord-350019-4nlbu54e	564	6	of	of	IN
cord-350019-4nlbu54e	564	7	the	the	DT
cord-350019-4nlbu54e	564	8	human	human	JJ
cord-350019-4nlbu54e	564	9	X	x	NN
cord-350019-4nlbu54e	564	10	inactivation	inactivation	NN
cord-350019-4nlbu54e	564	11	centre	centre	NN
cord-350019-4nlbu54e	564	12	is	be	VBZ
cord-350019-4nlbu54e	564	13	expressed	express	VBN
cord-350019-4nlbu54e	564	14	exclusively	exclusively	RB
cord-350019-4nlbu54e	564	15	from	from	IN
cord-350019-4nlbu54e	564	16	the	the	DT
cord-350019-4nlbu54e	564	17	inactive	inactive	JJ
cord-350019-4nlbu54e	564	18	X	x	NN
cord-350019-4nlbu54e	564	19	chromosome	chromosome	NN
cord-350019-4nlbu54e	565	1	The	the	DT
cord-350019-4nlbu54e	565	2	product	product	NN
cord-350019-4nlbu54e	565	3	of	of	IN
cord-350019-4nlbu54e	565	4	the	the	DT
cord-350019-4nlbu54e	565	5	H19	H19	NNP
cord-350019-4nlbu54e	565	6	gene	gene	NN
cord-350019-4nlbu54e	565	7	may	may	MD
cord-350019-4nlbu54e	565	8	function	function	VB
cord-350019-4nlbu54e	565	9	as	as	IN
cord-350019-4nlbu54e	565	10	an	an	DT
cord-350019-4nlbu54e	565	11	RNA	RNA	NNP
cord-350019-4nlbu54e	565	12	Support	Support	NNP
cord-350019-4nlbu54e	565	13	from	from	IN
cord-350019-4nlbu54e	565	14	:	:	:
cord-350019-4nlbu54e	565	15	National	National	NNP
cord-350019-4nlbu54e	565	16	Institute	Institute	NNP
cord-350019-4nlbu54e	565	17	of	of	IN
cord-350019-4nlbu54e	565	18	Health	Health	NNP
cord-350019-4nlbu54e	565	19	AR070973	AR070973	NNP
cord-350019-4nlbu54e	565	20	and	and	CC
cord-350019-4nlbu54e	565	21	the	the	DT
cord-350019-4nlbu54e	565	22	Tobacco	Tobacco	NNP
cord-350019-4nlbu54e	565	23	Related	Related	NNP
cord-350019-4nlbu54e	565	24	Disease	Disease	NNP
cord-350019-4nlbu54e	565	25	Research	Research	NNP
cord-350019-4nlbu54e	565	26	Program	Program	NNP
cord-350019-4nlbu54e	566	1	27IP-0017H	27ip-0017h	CD
cord-350019-4nlbu54e	566	2	to	to	IN
cord-350019-4nlbu54e	566	3	Susan	Susan	NNP
cord-350019-4nlbu54e	566	4	Carpenter	Carpenter	NNP
cord-350019-4nlbu54e	566	5	.	.	.
cord-350019-4nlbu54e	566	6	 	 	_SP