id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-005216-potmzdfs	Sun, Dong	Bioinformatics Analysis of Genes and Pathways of CD11b(+)/Ly6C(intermediate) Macrophages after Renal Ischemia-Reperfusion Injury	2018-03-15		.txt	text/plain	3294	180	49	Signet analysis showed that Atp5al, Atp5o, Cox4i, Cdc42, Rac2 and Nhp2 were the key genes involved in oxidation-reduction, apoptosis, migration, M1-M2 differentiation, and proliferation of macrophages. The identified DEGs and their enriched pathways investigate factors that may participate in the functional changes of CD 1lb(+)Ly6C(intermediate) macrophages after renal IRI. We used microarray analysis to identify the differentially expressed genes (DEGs) in CD11b + /Ly6C int macrophages of C57BL/6 mice and mice undergoing sham surgery or IRI for 4 h, 24 h or 9 days. To identify functional changes in macrophages, we analysed the role of DEGs in each significant expression profile. To identify the main biological function of CD11b + /Ly6C int macrophages, pathways of genes with similar expression trend were analysed. In this study, we analysed DEGs from CD11b + / Ly6C int macrophages, which were isolated from kidneys of mice undergoing sham surgery (n=2), and IRI at 4 h, 24 h, and 9 days (n=3 per group).	./cache/cord-005216-potmzdfs.txt	./txt/cord-005216-potmzdfs.txt