id author title date pages extension mime words sentences flesch summary cache txt cord-004893-28mrzvsc Pavesi, Angelo On the Informational Content of Overlapping Genes in Prokaryotic and Eukaryotic Viruses 1997 .txt text/plain 3783 161 48 At the level of codon usage, a low degree of correlation between overlapping and nonoverlapping coding regions characterized the first pattern, whereas a close link was found in tymoviruses, indicating a fine adaptation of the overlapping frame to the original codon choice of the virus. Here, we present an analysis at different levels of complexity (divergence from randomness of mono-and dinucleotide composition, choice of synonymous codons, and frequency of occurrence of amino acid residues) of the informational content of overlapping genes. The graphical representation ( Fig. 2) of the average values of the D 1 and D 2 indices, calculated by grouping the 12 viruses under examination in the five corresponding families (coliphage, hepatitis B virus, HIV-1 lentivirus, luteovirus, and tymovirus), led to the identification of two different informational patterns in the viral coding sequences. ./cache/cord-004893-28mrzvsc.txt ./txt/cord-004893-28mrzvsc.txt