id author title date pages extension mime words sentences flesch summary cache txt cord-355051-w18ptl0n Satoh, Ryoichi Characterization of T helper (Th)1‐ and Th2‐type immune responses caused by baculovirus‐expressed protein derived from the S2 domain of feline infectious peritonitis virus, and exploration of the Th1 and Th2 epitopes in a mouse model 2010-11-23 .txt text/plain 3228 158 51 title: Characterization of T helper (Th)1‐ and Th2‐type immune responses caused by baculovirus‐expressed protein derived from the S2 domain of feline infectious peritonitis virus, and exploration of the Th1 and Th2 epitopes in a mouse model In FP-HR2 protein-immunized mice, the concentrations of IFN-γ and IL-2 in the supernatant of splenocytes cultured with or without FIPV antigen were significantly higher than in that of splenocytes derived from wild-type baculovirus-infected SF-9-or PBS-immunized mice (P < 0.05, P < 0.01, respectively). In IH proteinimmunized mice, the concentration of IL-2 in the supernatant of splenocytes cultured with or without FIPV antigen was significantly higher than in that of splenocytes derived from wild-type baculovirus-infected SF-9or PBS-immunized mice (P < 0.05, P < 0.01, respectively). However, in PC protein-immunized mice, the concentrations of IFN-γ and IL-2 in the supernatant of splenocytes cultured with or without FIPV antigen were not significantly higher than in that of splenocytes derived from wild-type baculovirus-infected SF-9-or PBS-immunized mice. ./cache/cord-355051-w18ptl0n.txt ./txt/cord-355051-w18ptl0n.txt