id author title date pages extension mime words sentences flesch summary cache txt cord-254375-otj044by Paltrinieri, S Some aspects of humoral and cellular immunity in naturally occuring feline infectious peritonitis 1998-10-23 .txt text/plain 5148 268 45 Haematology, antibody titers and serum protein electrophoresis from 48 cats (34 effusive and 14 noneffusive forms) affected with feline infectious peritonitis (FIP) were studied and compared with those of 20 healthy cats. Even if antibody-enhanced infection has been recently questioned (Olsen et al., 1992 (Olsen et al., , 1993 Addie et al., 1995) , many experimental results demonstrate that anti-FCoV antibodies facilitate the uptake of the virus by the macrophages (Hayashi et al., 1983; Stoddart and Scott, 1989 ; Barlough and Stoddart, 1990; Hohdatsu et al., 1994; Pedersen, 1995a) , and that immunocomplexes lead to a type III hypersensitivity reaction with disseminated intravascular coagulation and fibrinoid necrosis of the vessel's walls, responsible for the effusions (Hayashi et al., 1977 (Hayashi et al., , 1978 Pedersen and Boyle, 1980; Weiss et al., 1980; Jacobse-Geels et al., 1980; Weiss and Scott, 1981; Fenner, 1987; Pastoret and Bourtonboy, 1991; Pedersen, 1995a) . To further understand the pathogenesis of the disease, parameters indicative of the involvement of humoral immunity (total and fractioned proteins and antibody titers in serum and in effusions), and the distribution of viral antigen and immune cells in the lesions were studied in cats with spontaneous FIP. ./cache/cord-254375-otj044by.txt ./txt/cord-254375-otj044by.txt