Summary of your 'study carrel' ============================== This is a summary of your Distant Reader 'study carrel'. The Distant Reader harvested & cached your content into a collection/corpus. It then applied sets of natural language processing and text mining against the collection. The results of this process was reduced to a database file -- a 'study carrel'. The study carrel can then be queried, thus bringing light specific characteristics for your collection. These characteristics can help you summarize the collection as well as enumerate things you might want to investigate more closely. This report is a terse narrative report, and when processing is complete you will be linked to a more complete narrative report. Eric Lease Morgan Number of items in the collection; 'How big is my corpus?' ---------------------------------------------------------- 48 Average length of all items measured in words; "More or less, how big is each item?" ------------------------------------------------------------------------------------ 7676 Average readability score of all items (0 = difficult; 100 = easy) ------------------------------------------------------------------ 49 Top 50 statistically significant keywords; "What is my collection about?" ------------------------------------------------------------------------- 44 family 10 COVID-19 7 care 5 child 4 patient 4 covid-19 4 Family 3 time 3 pandemic 2 work 2 study 2 school 2 protease 2 peptidase 2 experience 2 education 2 ICU 2 Human 2 Cys 2 Canada 1 way 1 victim 1 variant 1 transition 1 therapy 1 therapist 1 target 1 system 1 syndrome 1 student 1 social 1 sequencing 1 sequence 1 self 1 sample 1 role 1 risk 1 result 1 research 1 relationship 1 reach 1 psychological 1 protein 1 plant 1 performance 1 pediatrician 1 parent 1 opioid 1 mutation 1 member Top 50 lemmatized nouns; "What is discussed?" --------------------------------------------- 3773 family 1166 care 1128 patient 943 child 874 health 809 gene 758 study 739 time 705 mutation 660 % 599 protease 550 case 516 member 516 disease 500 analysis 494 protein 487 parent 476 life 471 pandemic 443 cell 442 community 435 research 418 home 417 risk 400 inhibitor 396 role 389 variant 385 work 385 p 382 datum 362 activity 347 need 342 group 339 system 338 relationship 330 experience 330 effect 321 support 321 level 317 school 313 individual 310 enzyme 300 development 290 result 288 year 287 loss 286 mother 282 business 277 way 277 factor Top 50 proper nouns; "What are the names of persons or places?" -------------------------------------------------------------- 942 al 788 et 598 . 405 COVID-19 233 Family 160 • 140 ICU 105 Health 105 Germany 90 Care 88 RNA 85 China 83 University 81 United 81 Human 75 States 75 Institute 75 C 74 Cys 69 FTD 66 NGS 65 ID 64 US 64 SARS 63 B 61 M. 59 novo 59 Canada 56 National 54 Fig 53 de 53 J 52 New 51 T 51 Genetics 51 A 50 CA 50 A. 49 Table 49 S. 48 e. 46 nonfarmworker 46 USA 45 Protein 44 S8 44 PCR 43 WES 41 March 41 DE 40 sha Top 50 personal pronouns nouns; "To whom are things referred?" ------------------------------------------------------------- 1640 we 917 it 875 they 519 i 292 them 273 she 159 us 134 you 83 he 80 her 76 me 62 themselves 37 one 22 itself 20 ourselves 19 him 13 myself 12 herself 7 's 5 oneself 3 w2w 3 theirs 3 mutationtaster3 2 himself 1 zfpm2 1 yours 1 year….they 1 ya 1 tssm 1 mir371a-3p 1 iga1 1 ifih1 1 hers 1 gata1 1 etc.)they Top 50 lemmatized verbs; "What do things do?" --------------------------------------------- 10612 be 2786 have 781 use 645 include 588 show 570 do 524 identify 458 provide 381 find 348 associate 339 increase 332 know 330 base 326 report 301 make 296 work 287 describe 284 need 274 affect 265 develop 252 relate 238 cause 234 take 233 help 227 see 223 reduce 223 involve 216 live 214 support 203 lead 200 protect 197 become 195 suggest 193 follow 190 consider 189 require 179 perform 173 compare 172 reveal 169 learn 167 give 163 care 161 present 158 improve 158 contribute 156 result 154 experience 151 understand 150 go 149 share Top 50 lemmatized adjectives and adverbs; "How are things described?" --------------------------------------------------------------------- 1172 not 788 more 746 other 738 also 563 well 529 high 501 - 427 such 408 social 404 only 360 most 334 clinical 333 new 333 low 330 many 326 different 325 important 317 however 307 genetic 297 medical 292 as 281 first 267 mental 263 specific 251 further 242 old 231 human 220 psychological 217 non 216 likely 214 often 209 large 203 several 201 long 199 positive 197 early 192 public 189 even 182 e.g. 178 primary 176 same 174 economic 174 catalytic 171 so 166 small 165 complex 159 physical 158 significant 157 common 155 less Top 50 lemmatized superlative adjectives; "How are things described to the extreme?" ------------------------------------------------------------------------- 126 most 58 good 45 least 33 high 32 Most 24 great 14 large 11 strong 11 bad 8 young 7 low 4 close 3 rich 3 big 2 weak 2 slight 2 simple 2 short 2 poor 2 harsh 2 MOST 1 −5.4 1 wild 1 tough 1 tight 1 small 1 near 1 mpimg1-t 1 long 1 late 1 full 1 fit 1 few 1 fast 1 dark 1 cord-352141-y3s8li0v 1 cord-005147-mvoq9vln 1 common 1 broad 1 -which 1 -occur Top 50 lemmatized superlative adverbs; "How do things do to the extreme?" ------------------------------------------------------------------------ 234 most 43 least 14 well 1 worst 1 hard 1 early 1 -gly479+arg Top 50 Internet domains; "What Webbed places are alluded to in this corpus?" ---------------------------------------------------------------------------- 4 www.mutationtaster.org 4 doi.org 3 orcid.org 1 youtu.be 1 www.proteolysis.org 1 www.narrativetherapyinitiative.org 1 www.migrantclinician.org 1 www.claudiacuentas.com 1 varbank.ccg.uni-koeln.de 1 tinyurl.com 1 reauthoringteaching.com 1 merops.sanger.ac.uk 1 merops.sanger 1 ltc-217 1 dnamage.genetics.ucla.edu 1 creat Top 50 URLs; "What is hyperlinked from this corpus?" ---------------------------------------------------- 4 http://www.mutationtaster.org 4 http://doi.org/10.1101/2020.10.13.20212118 1 http://youtu.be/ib2HavPl_ac. 1 http://www.proteolysis.org/ 1 http://www.narrativetherapyinitiative.org 1 http://www.migrantclinician.org/witness-to-witness 1 http://www.claudiacuentas.com 1 http://varbank.ccg.uni-koeln.de 1 http://tinyurl.com/yaz5rvar 1 http://reauthoringteaching.com 1 http://orcid.org/0000-0002-9094-8123 1 http://orcid.org/0000-0002-3490-3027 1 http://orcid.org/0000-0001-7215-3629 1 http://merops.sanger.ac.uk/ 1 http://merops.sanger 1 http://ltc-217 1 http://dnamage.genetics.ucla.edu 1 http://creat Top 50 email addresses; "Who are you gonna call?" ------------------------------------------------- 1 mosconia1@gmail.com 1 boestergaard@health.sdu.dk 1 ab9@sanger.ac.uk Top 50 positive assertions; "What sentences are in the shape of noun-verb-noun?" ------------------------------------------------------------------------------- 5 disease causing mutations 4 disease causing variants 4 proteases are important 3 analyses did not 3 families were able 3 parents are heterozygous 3 parents did not 3 patients do not 3 studies did not 2 % were concerned 2 care does not 2 care is more 2 cases were significantly 2 child did not 2 communities have higher 2 disease related genes 2 families are also 2 families are often 2 families are unable 2 families did not 2 families do not 2 families include members 2 home is essential 2 home is not 2 inhibitors have not 2 mutation did not 2 mutation is already 2 parents were heterozygous 2 patients are unable 2 patients had relative 2 proteases are also 2 proteases include members 2 role is also 2 study are available 1 % are dependent 1 % are homozygotes 1 % were able 1 % were african 1 % were female 1 % were intronic 1 % were part 1 % were white 1 analyses are currently 1 analyses are ongoing 1 analyses including mlpa 1 analyses provide functional 1 analyses provide insights 1 analyses showed genetic 1 analyses using alamut 1 analyses using microsatellite Top 50 negative assertions; "What sentences are in the shape of noun-verb-no|not-noun?" --------------------------------------------------------------------------------------- 2 inhibitors have not yet 1 analysis showed no numerical 1 care is no longer 1 care was no longer 1 child is not happy 1 children have no heart 1 children is not available 1 families are not always 1 home are not trivial 1 home is not yet 1 homes had not fully 1 life is not reliably 1 members are not able 1 mutation was not detectable 1 mutations are not always 1 mutations were not significantly 1 pandemic has no precedent 1 pandemic has not only 1 pandemic is not only 1 parents were not totally 1 study are not publicly A rudimentary bibliography -------------------------- id = cord-354941-0ocsf255 author = Amorin‐Woods, Deisy title = Family Therapy and COVID‐19: International Reflections during the Pandemic from Systemic Therapists across the Globe date = 2020-06-08 keywords = COVID-19; Family; Therapy; experience; pandemic; system; therapist; time summary = This paper offers a collection of reflections by systemic and family therapists from diverse cultures and contexts penned in the midst of the pandemic. I felt as if these early collections merged into one, represent the ''holding, healing space'' that we as therapists need, before we dare consider what life may look like on the ''other side.'' Without this, how could we support our clients in putting themselves, their families, and their lives back together, in even contemplating what a world of ''functionality'' or ''normality'' may look like? It is crucial that we are able to name and process our experiences in order to support our Global Family Therapists reflect on COVID-19 ª 2020 Australian Association of Family Therapy clients to do the same, in order to provide the holding space they need, and joining-in with them (Minuchin, 1974) . doi = 10.1002/anzf.1416 id = cord-263650-jxkjn8ld author = Andruske, Cynthia Lee title = Family care across diverse cultures: Re-envisioning using a transnational lens date = 2020-10-20 keywords = Canada; South; age; care; family summary = Specifically, drawing on a broad understanding of care that is consistent with Fisher and Tronto (1990) ; also Tronto, 2013) , the purpose of our study was to explore and compare the relationships between culture and informal family care practices across three diverse ethno-cultural groups: Chinese, South Asians, and Latin Americans living in Vancouver, British Columbia, Canada. Adults self-identifying as Chinese, South Asian, and Latin American, and providing unpaid, informal care or support to someone over the age of 65 needing some level of assistance with activities of daily living, were invited to participate. Even only adult children like Argentinian Rossana pointed out that she had created networks from her family (husband, daughter, and grandchildren, among others) and paid companions as well as her 92-year-old mother''s long-time friends to provide support and care. doi = 10.1016/j.jaging.2020.100892 id = cord-006934-92ctgc4n author = Barrett, Alan J. title = Families and clans of cysteine peptidases date = 1996 keywords = Cys; family; peptidase summary = In all the cysteine peptidases discovered so far, the activity depends upon a catalytic dyad, the second member of which is a histidine residue acting as a general base. The amino acid sequences of the cysteine peptidases of picornaviruses (picornains 2A and 3C) (family C3) hint at a relationship with chymotrypsin [34] , and when the threedimensional structure of picornain 3C from the human hepatitis A virus was determined, it showed unmistakable similarities to that of chymotrypsin and other members of clan SA [6, 35] . There are additionally many polyprotein processing endopeptidases from RNA viruses that have the Cys/His catalytic dyad, and also show the bulky hydrophobic amino acid following the catalytic cysteine that is characteristic of the papain clan. The three-dimensional structure of interleukin-l[3-converting enzyme shows a distinctive protein fold, and thus a separate origin for this group of cysteine peptidases [7, 8] . doi = 10.1007/bf02174042 id = cord-010411-zgdvo29n author = Biglan, Anthony title = A Strategic Plan for Strengthening America’s Families: A Brief from the Coalition of Behavioral Science Organizations date = 2020-04-28 keywords = Biglan; behavior; child; family; intervention; school summary = As noted above, schools in high poverty neighborhoods and communities have higher rates of punitive practices and fewer resources for preventing the development of problem behavior (American Psychological Association, n.d.). Given the extent of discrimination in the USA, its impact on public health, and the size of the workforce, it is imperative that foundations and the NIH fund research to identify more effective ways to reduce prejudice in schools, work settings, and neighborhoods and communities. While it is true that addressing the above-described contextual conditions is likely to improve family well-being significantly, it is unlikely that reducing problems like poverty and discrimination will ensure that every family and school adopt the most effective ways of nurturing children''s development . Evidence of the value of both economic development efforts and programs targeting families and schools suggests it is time to test comprehensive interventions that simultaneously address all risk factors for problems for which we have some effective solutions. doi = 10.1007/s10567-020-00318-0 id = cord-013286-5lxy8qrq author = Bolarinwa, Obasanjo A. title = Factors associated with low contraceptive use amongst vulnerable mothers in South West State, Nigeria date = 2020-09-18 keywords = Nigeria; family summary = Aim: This study aimed to identify and analyse the factors associated with the low use of contraceptives amongst vulnerable women in the South West region in Nigeria. Aim: This study aimed to identify and analyse the factors associated with the low use of contraceptives amongst vulnerable women in the South West region in Nigeria. 22 Hence, there are critical needs to examine the family type, living arrangement and contraceptive use amongst vulnerable mothers in South West, Nigeria. The study was quantitative research, which employed a cross-sectional descriptive survey design to elicit information on family planning use, family types and living arrangements amongst vulnerable mothers in Osun State, Nigeria using a structured questionnaire. Although the prevalence level of contraceptive use amongst sexually active men and women is low in Nigeria, 8, 10, 20 we studied variations by living arrangements and family types in the use of any family planning method amongst young mothers. doi = 10.4102/phcfm.v12i1.2552 id = cord-335582-30rws724 author = Bonal, Xavier title = The impact of lockdown on the learning gap: family and school divisions in times of crisis date = 2020-09-15 keywords = child; education; family; school; student summary = Middle-class families were able to maintain higher standards of education quality in a critical context, while children from socially disadvantaged families had few learning opportunities both in terms of time and learning experiences (schoolwork and maintenance of after-school activities). During the COVID-19 Catalan lockdown, the instructional time received by students from different social backgrounds has been unequal, as has the educational value of the activities developed at home in non-school time. Extant research evidence based on these experiences identifies the existence of a general loss of learning connected to school absence, which can be more or less severe depending on students'' previous performance, family characteristics, age, and education pathway, among other factors. Inequalities in families'' economic, social and cultural capital impacted on student learning opportunities by different means, including school responses to the lockdown, access to digital facilities and the level of parental learning support. doi = 10.1007/s11159-020-09860-z id = cord-352141-y3s8li0v author = Bouchoucha, Stéphane title = Family‐centred care during a pandemic: The hidden impact of restricting family visits date = 2020-06-13 keywords = covid-19; family summary = While it may be too early in the COVID-19 pandemic to realise the potential impact of compassion fatigue and burnout on nurses, evidence collected following the severe acute respiratory syndrome (SARS) epidemic (Maunder et al., 2006) showed that healthcare workers that cared for patients with SARS had higher levels of burnout, psychological distress and post-traumatic stress than other healthcare workers. From what we know about factors that may increase risks of compassion fatigue and burnout, having to limit visits for family members of critical ill and dying patients is likely to also have a negative impact on nurses by increasing their feelings of providing inadequate family-centred care. Restricting family visits, while a necessary measure to decrease the spread of COVID-19 to vulnerable patients and the community, is likely to have negative effects on families and nurses alike and these impacts need to be carefully considered. doi = 10.1111/nhs.12748 id = cord-302421-tvy7uo7u author = Brock, Rebecca L. title = Family Science in the Context of the COVID‐19 Pandemic: Solutions and New Directions date = 2020-07-14 keywords = COVID-19; family; pandemic; research summary = The primary aims of this article were to (a) present a range of potential solutions to problems threatening the rigor of ongoing research and (b) propose new directions in family science aimed at understanding how families adapt to change and adversity arising from the pandemic. An example with particular relevance to family science is the Two-Method Missing Design, an approach used when there is a gold standard measure of a construct (e.g., behavioral observations of family interactions) that cannot be administered to all participants due to time, money, resources, or, in the case of COVID-19, social distancing guidelines. Drawing on past research and theory, we can investigate the specific impact of the stress and adversity arising from COVID-19 on individual mental health and family functioning and identify modifiable risk and resiliency factors to target in interventions. In the absence of ongoing longitudinal studies, the COVID-19 pandemic presents another avenue for family scientists to pursue new research on the impact of stress and adversity on family functioning. doi = 10.1111/famp.12582 id = cord-354194-hf5ndv5f author = Cook, Mackenzie title = Prioritizing Communication in the Provision of Palliative Care for the Trauma Patient date = 2020-10-29 keywords = ICU; care; family; patient summary = Communicating clearly as part of providing high-quality palliative care in the intensive care unit (ICU) is about guiding difficult decisions, defining goals of care, explaining the impact of acute surgical problems on future quality of life, and facilitating transitions to end of life care [2, 3] . Given that the vast majority of severely injured trauma patients in the ICU have limited abilities to function as their own decision makers, this discussion will primarily focus on the interactions with family and surrogate decision makers as this is the group most in need of high-quality communication [6, 37] . The routine integration of trained palliative care subspecialists in the ICU has been associated with improved quality of life, higher rates of formal advance directives, and greater utilization of hospice service as well as less frequent use of certain non-beneficial life-prolonging treatments for critically ill patients at the end of life [49] . doi = 10.1007/s40719-020-00201-x id = cord-010837-8x3bch0r author = Curran, Janet A. title = Improving transitions in care for children with complex and medically fragile needs: a mixed methods study date = 2020-05-14 keywords = care; child; family; transition summary = In Phase 2, pediatricians, nurses, and health administrators participated in key stakeholder interviews to identify barriers and facilitators to a successful transition in care for children and families with complex care needs. (2) other parents on the inpatient unit act as key supports to the family; (3) satisfaction with the care from the local community pediatrician, but dissatisfaction with care received from the community hospital following misplacement of the child''s feeding tube; (4) an advanced practice nurse guiding the discharge process and using a locally developed tool to guide discharge planning that was distributed to the family and home community to promote continuity of care; (5) a high level of engagement from the family helping to facilitate a smooth transition as reported by the health care team; and (6) a lack of pediatric expertise in community physiotherapy. doi = 10.1186/s12887-020-02117-6 id = cord-272901-dsnbh4t1 author = Dew, Jeffrey title = Ten Years of Marriage and Cohabitation Research in the Journal of Family and Economic Issues date = 2020-10-22 keywords = family; marital; relationship; study summary = Thus, although no one aspect, theme, or methodology links the 36 studies I reviewed, many of them examined issues related to family structure and/or economic changes that have occurred over the past sixty years in the US and other nations. For the purposes of this review, I categorized a study as examining an underrepresented group if the sample was largely composed of individuals from race/ethnic minority groups, interracial couples, sexual minorities, low-income families, or from countries outside the United States. Many of the studies of the association between financial issues and relationship quality over the past three years have focused on the family stress model of economic pressure and marital distress (Conger et al. 1990 ), or simply "family stress model." Since its inception in 1990, many scholars have used this model to research the association between negative financial events, feelings of economic pressure, and marital quality. doi = 10.1007/s10834-020-09723-7 id = cord-308267-c4wu92tt author = Dickerson, Victoria C. title = The “Flip”—Sustaining Complexity and Multiplicity Post‐Quarantine date = 2020-07-14 keywords = Zoom; family; therapy; way summary = Linking‐Lives Storython, created specifically to utilize our Covid shelter‐in‐place experience; Re‐Authoring Teaching: Creating a Collaboratory, begun 12 years ago to meet the needs of a wide‐spread community; and Witness‐to‐Witness, a current response to contemporary disastrous situations—all have utilized technology to open possibilities for those who are helped as well as those who are helpers. We began to recognize what had been unremarkable to us previously: what it means to interact as clinician and client in a therapy room, in a physical space designed specifically for the sharing of experience, for personal communication and understanding. Is there a way to think about our current dilemma of pandemic/quarantine, our need to rely on technology in our systems work, that could help us see a way forward from a "positive deviance" understanding? doi = 10.1111/famp.12583 id = cord-276741-ptrehipn author = Erdei, Carmina title = The downstream effects of COVID-19: a call for supporting family wellbeing in the NICU date = 2020-07-24 keywords = NICU; family summary = In this paper, we propose utilizing the stress contagion framework and consider how psychosocial stress can "spill over" into the parent-infant relationship domain, which can impact child development and family wellbeing longer term. Although newborns may be less impacted by COVID-19 directly, there is concern that the pandemic and the necessary public health measures employed in response may negatively impact the psychosocial health of high-risk infants and their families in the Neonatal Intensive Care Unit (NICU). As the neonatal community has expeditiously employed novel strategies to meet the medical needs of infants affected by COVID-19, it is important to also consider the psychological short-and long-term effects of the pandemic on NICU families. As stress contagion in the NICU can negatively impact parent-infant relationships, strategies are needed to mitigate it in order to optimize child development and family resilience during this unparalleled period. doi = 10.1038/s41372-020-0745-7 id = cord-271867-n563yqw4 author = Falicov, Celia title = Expanding Possibilities: Flexibility and Solidarity with Under Resourced Immigrant Families During the Covid‐19 Pandemic date = 2020-07-14 keywords = Falicov; Rocío; client; covid-19; family; health summary = We compare and contrast the learnings of flexibility of time, space, procedures or attendance we acquired in this clinical community setting during regular times, with the new challenges families and therapists face, and the adaptations needed to continue to work with our clients in culturally responsive and empowering ways during the Covid‐19 pandemic. During Covid-19, the SRFC physicians, pharmacy team, medical students, staff, volunteers, mental health team, social workers, and promotoras (experienced community members who are core staff and act as "trust bridges" to the community (Beck, 2005) ) have come together to continue to provide health, mental health care and emotional support through telemedicine and delivery of medications and food to patients'' homes. Relying on our learnings about providing services to under resourced families and communities in regular times, during the Covid-19 pandemic we expand the limits of what appears possible in a variety of new ways. doi = 10.1111/famp.12578 id = cord-261424-t0yulofo author = Feltman, Dalia M. title = Seeking Normalcy as the Curve Flattens: Ethical Considerations for Pediatricians Managing Collateral Damage of COVID-19 date = 2020-06-26 keywords = COVID-19; child; family; pediatrician summary = Pediatricians around the world have cycled through these emotions when considering the health and safety of patients and families during this coronavirus disease 2019 (COVID19) pandemic. As advocates for children, pediatricians are in a unique position to redesign the system in a way that prioritizes children and families, addresses the social determinants of health, reduces inequalities and health disparities, and ensures ethical research on treatment and prevention of COVID-19. However, actions to conserve the medical resources that prevent iatrogenic spread of infection and protect health professionals and other patients have shifted priorities away from the best practices that are part of our usual care for children. As we begin to imagine that new normal, we consider three domains that require attention to help children to stay well: medical, mental health, and educational needs. Children in families with mental health needs will be vulnerable to further disruptions to their psychosocial stability due to COVID-19 control measures. doi = 10.1016/j.jpeds.2020.06.067 id = cord-347105-my9nioko author = Foster, Carolyn C. title = Integrated Multimodality Telemedicine to Enhance In-Home Care of Infants During the Interstage Period date = 2020-10-20 keywords = care; family; patient summary = So, while these tools provide important care delivery options, home surveillance based on asynchronous teleIHM and V/P sharing alone may still result in frequent patient travel for routine in-person evaluations or necessitate family-provider phone calls to discuss or clarify asynchronously collected information. For limited English Proficiency families, translation was provided by an interpreter who was placed on speaker phone by the cardiac provider during the VVs. The Integrated Multimodality Telemedicine Care Model for Infants During the Interstage Period is shown in Fig. 1 demonstrating the high-level integration of VVs with teleIHM and V/P sharing for patients followed in the interstage program. This evaluation found that the integration of scheduled, routine VVs with remote home monitoring (teleIHM) through a multidisciplinary advanced practice model can feasibly enhance the care of in infants during the interstage period with overall high family acceptability. doi = 10.1007/s00246-020-02489-7 id = cord-265323-urecb44o author = Fraenkel, Peter title = Reaching Up, Down, In, and Around: Couple and Family Coping During the Corona Virus Pandemic date = 2020-06-26 keywords = Fraenkel; article; copyright; couple; family; reach; social summary = Challenges include Illness, death, and the fears thereof; employment and economic losses the growing evidence of heath care disparities between persons of differing social locations in terms of race, ethnicity, socioeconomic status, profession, and citizenship status; fears of losing housing, access to food and other basic needs; lack of consistent information about the level of risk of infection or guidance about best practices to reduce that risk; the need to quarantine with partners and family members despite conflicts that are usually mitigated somewhat by daily distance through going to work and school, and on the other hand, interminable separations between family members, friends, and community; a sense of foreboding, isolation, and lack of social support; and disruption of life plans and rituals such as birthdays, weddings, religious holidays, recreational activities, and funerals. doi = 10.1111/famp.12570 id = cord-349353-2ll9hzfr author = Giordano, Chiara title = Freedom or money? The dilemma of migrant live‐in elderly carers in times of COVID‐19 date = 2020-07-04 keywords = COVID-19; care; family; work summary = Concerning the latter, as it has repeatedly been stressed, the COVID-19 crisis has and will have an impact on various aspects of gender equality, including the economic hardship falling on women whose economic position is precarious, which is the case of many single-parent households; the sharpening of domestic violence; the hazardous situation of workers in the frontline, the majority of whom are women; and the increased burden of unpaid care and housework responsibilities during the lockdown period 1 . Both elementsthe emotional ties between caregiver and care receiver and the position of live-in caregivers as ''quasi-family members''have crucial consequences on the lives and choices of live-in elderly carers in times of COVIDAs mentioned in the previous section, the very nature of care work, including the gendered construction of the ideals and values associated to it and the emotional labour that shapes their This article is protected by copyright. doi = 10.1111/gwao.12509 id = cord-343910-jib877fo author = Guidotti, M. title = Does autism protect against COVID quarantine effects? date = 2020-10-14 keywords = child; family summary = 95 autistic children followed by the child and adolescent psychiatry department of Tours university hospital were assessed from the 18th of March to the 8th of May. The following clinical points were investigated: child anxiety, family anxiety, behavior problems, impact on sleep, impact on appetite, impact on school work, family tension, confinement intolerance, difficulties to follow a schedule, isolation behavior. Results: Despite minor changes in family anxiety and school work, no difference was highlighted between clinical scores collected at the beginning and at the end of this period. . https://doi.org/10.1101/2020.10.13.20212118 doi: medRxiv preprint Eight clinical items (child anxiety, behavior problems, impact on sleep, impact on appetite, family tension, confinement intolerance, difficulties to follow a schedule, isolation behavior) had an average score of less than 2 and two items (family anxiety and impact on school work) were greater than 2 at both T1 and T2 time points (Fig.1) . doi = 10.1101/2020.10.13.20212118 id = cord-308014-130k8v21 author = Happ, Mary Beth title = Family Caregiving for Acute-Critically Ill Older Adults in the Time of COVID-19 date = 2020-10-21 keywords = caregiver; family summary = title: Family Caregiving for Acute-Critically Ill Older Adults in the Time of COVID-19 It is fitting that in this last year, we observed Geriatric Nursing''s 40 th anniversary with several columns that involved "taking stock" of acute-critical care for older people as well as review of progress on ageism, physical restraint use, and accommodations for patient communication impairment in acute-critical care. Vulnerable older patients enter acute-critical care settings without the supportive presence and advocacy of family caregivers. Gerontological nurses are uniquely qualified to support family caregivers as they interact with acute-critical care in remote and creative ways during the COVID-19 pandemic. Family Caregiving for Older Adults admitted to Acute -Critical Care COVID-related family separation during acute-critical illness impacts older adult patients, family caregivers, and nurses on multiple levels and is likely to have long-term traumatic effects. [8] Health policy and programmatic initiatives are desperately needed to provide tangible support for family caregivers of frail older adults. doi = 10.1016/j.gerinurse.2020.10.008 id = cord-333663-0yzrcfe5 author = Hart, Joanna L. title = Family-Centered Care During the COVID-19 Era date = 2020-04-22 keywords = COVID-19; family summary = However, during the COVID-19 pandemic, maintaining public safety necessitates restricting the physical presence of families for hospitalized patients. We provide a toolbox of strategies for supporting family-centered inpatient care during physical distancing responsive to the current clinical climate. Strategies for delivering family-centered care typically include open family presence at the bedside; 3 regular, structured communication with family members; and multidisciplinary support. 3 Physical, or social, distancing is the principal mitigation strategy used to reduce transmission in the COVID-19 pandemic, 4 with a profound impact on the delivery of family-centered inpatient care. During the COVID-19 pandemic, family presence must be supported in non-physical ways to achieve the goals of family-centered care. Family-centered care strategies in this context must acknowledge the changed ethical perspective and clinicians'' limited time, attention, and effort to devote to learning and assimilation. Strategies to support family presence during physical distancing rely heavily on existing patient or family smartphones and computers, stable internet access, and technological literacy. doi = 10.1016/j.jpainsymman.2020.04.017 id = cord-280619-xcre2zgh author = Harvey, Bart J. title = Identifying Public Health Competencies Relevant to Family Medicine date = 2011-09-28 keywords = Canada; Family summary = Using a multi-staged, iterative process that included a detailed literature review, the authors developed a set of public health competencies relevant to primary care, identifying competencies relevant across four levels, from "post-MD" to "enhanced." Feedback from family medicine and public health educator–practitioners regarding the set of proposed "essential" competencies indicated the need for a more limited, feasible set of "priority" areas to be highlighted during residency training. This focused set of public health competencies has begun to guide relevant components of the University of Toronto''s Family Medicine Residency Program curriculum, including academic half-days; clinical experiences, especially identifying "teachable moments" during patient encounters; resident academic projects; and elective public health agency placements. This revised draft was then sent to all symposium participants for additional review and feedback, which resulted in the proposal of a detailed set of public health competencies relevant to family medicine and primary care (Appendix B, available online at www.ajpmonline.org). doi = 10.1016/j.amepre.2011.06.002 id = cord-034464-yt5uyqb4 author = Haynes, George title = Family business research: Reviewing the past, contemplating the future date = 2020-10-31 keywords = JFEI; business; family summary = In the future, family business researchers have the opportunity to better understand the impact of community resources and climate; more carefully assess the challenges of women, minorities, and immigrants; understand the role of cultural capital; and explore the impact of innovation during rapidly changing times, such as those created by the pandemic. The foundation provided by Yilmazer and Schrank (2010) was important in the development of a research study by McDonald and Marshall (2018) , which used Sustainable Family Business Theory (SFBT) and Intergeneration Family Business Survey data. Based on suggestions by Yilmazer and Schrank (2010) , household and business economic research in the JFEI explored the importance of cash flow, profitability, and savings in supporting family business well-being, satisfaction, success, and survival. The JFEI literature explored adjustment strategies employed by women and minority family business owners during hectic times; and, considered the importance of capital use and innovative technologies in managing the firm. doi = 10.1007/s10834-020-09732-6 id = cord-272923-5ekgb0zx author = Hjálmsdóttir, Andrea title = “I have turned into a foreman here at home.” Families and work‐life balance in times of Covid‐19 in a gender equality paradise. date = 2020-09-19 keywords = Iceland; family; home; time; work summary = In Iceland, as elsewhere, women work part-time jobs in higher numbers, and mothers reduce their labor participation following childbirth more often than do fathers (Gíslason & Símonardóttir, 2018) . In the following example, a mother of a 2-year-old working in mass media, who worked entirely from home as did her husband, described one of her days like this: "I''m a little anxious because of all this, the situation in society. This is in accordance with previous studies on gendered control of time among parents (Bryson, 2016; Friedman, 2015) and new research conducted during Covid-19 that indicate that unpaid work performed by mothers has increased during the pandemic (Craig & Churchill, 2020; Manzo & Minello, 2020) . One of the patterns identified in the reflections of the women in our study was how they seemed to be stunned by how uneven the division of labor turned out to be during the pandemic and how much time and energy they devoted to household chores and the management of the household, carrying out the mental work within the family. doi = 10.1111/gwao.12552 id = cord-322679-jrsg8pdk author = Hu, Na title = Impact of the Family Environment on the Emotional State of Medical Staff During the COVID-19 Outbreak: The Mediating Effect of Self-Efficacy date = 2020-10-09 keywords = family; medical; self summary = Our study also indicates that improvements in the family environment benefit the mental health care of the medical staff, and high self-efficacy enhances this effect. Mediating effect analysis was performed to explore the role of self-efficacy in the relationship between family environment and symptoms of anxiety and depression. The results showed that there were statistically significant relationships between the anxiety and depressive symptoms of medical staff, their family environment, and their sense of self-efficacy. The medical staff members with low cohesion and expressiveness, as well as high conflict in the family environment, were more likely to show anxiety and depressive symptoms during the epidemic. In the current study, we found that the anxiety and depressive symptoms of medical staff during the COVID-19 outbreak was closely related to their family environment, and their self-efficacy regulated the relationship between them. doi = 10.3389/fpsyg.2020.576515 id = cord-324857-ll3xmk3i author = Jenkins, Louis S. title = The evolving role of family physicians during the coronavirus disease 2019 crisis: An appreciative reflection date = 2020-06-09 keywords = COVID-19; family summary = Ten family physicians and family medicine registrars in a South African semi-rural training complex reflected on the coronavirus disease 2019 (COVID-19) crisis during their quarterly training complex meeting. Ten family physicians and family medicine registrars in a South African semi-rural training complex reflected on the coronavirus disease 2019 (COVID-19) crisis during their quarterly training complex meeting. The importance of preventative and promotive care in a community-oriented approach, being a capacity builder and leading the health team as a consultant have assumed new meanings. The importance of preventative and promotive care in a community-oriented approach, being a capacity builder and leading the health team as a consultant have assumed new meanings. The roles of the family physician in South Africa and the contribution to district health services have been well described. Figure 2 (left side) presents the ''traditional'' model of how a family physician might exercise his or her roles during the COVID-19 crisis. doi = 10.4102/phcfm.v12i1.2478 id = cord-322907-e0pmyvdq author = Kaiper-Marquez, Anna title = On the fly: Adapting quickly to emergency remote instruction in a family literacy programme date = 2020-10-14 keywords = ILA; education; family; parent summary = Even Start integrated "early childhood education, adult literacy (adult basic and secondary-level education and instruction for English language learners), parenting education, and interactive parent and child literacy activities for low-This article examines how instructors at the Goodling Institute for Research in Family Literacy (GI) at The Pennsylvania State University have responded to the pandemic by converting face-to-face family literacy classes into online, remote instruction. We argue that although the pandemic has presented unprecedented challenges for adult educators and learners in the United States (US) and around the world, it has also compelled instructors to use remote instruction creatively and has revealed the critical importance of family literacy programmes as an educational support system for families. In one of the only studies examining DE in family literacy, Beschorner and Hutchison (2016) compared the experiences and outcomes of adult learners completing a parent education class through face-to-face classes with those who had received online instruction. doi = 10.1007/s11159-020-09861-y id = cord-012387-1ogcxd7b author = Kaufman, Aaron R. title = The political consequences of opioid overdoses date = 2020-08-04 keywords = family; opioid; victim summary = This paper applies a validated causal research design to study the political consequences of the opioid epidemic on the individuals closest to it-the friends and family of overdose victims. In contrast to other studies examining the effects of tragedy on political participation, we find that friends and family of opioid overdose victims are less likely to turn out to vote than they were before tragedy struck, even compared to victims of premature cancer or a demographically-matched sample of registrants without familial opioid overdoses. We identify in public voter registration records the friends and family of opioid overdose victims, and compare their election turnout rates and party identification in the elections immediately before and after their loved one''s death. By comparing political behaviors of these matched groups to the original samples of family members, we control for all observed (but not unobserved) factors that might confound the relationship between cancer or opioid overdose deaths and voter turnout. doi = 10.1371/journal.pone.0236815 id = cord-291361-2vn1o7ag author = Li, Jing title = Epidemiological and clinical characteristics of three family clusters of COVID-19 transmitted by latent patients in China date = 2020-07-06 keywords = SARS; family summary = title: Epidemiological and clinical characteristics of three family clusters of COVID-19 transmitted by latent patients in China The epidemiological and clinical characteristics of the family cluster patients were analysed and compared with those of 43 contemporaneous sporadic cases. In terms of epidemiological characters and clinical symptoms, no significant differences were observed between the family cluster and sporadic cases. In this study, we aimed to investigate the epidemiological and clinical characteristics of these three family clusters of COVID-19 cases by comparing them with sporadic cases, which would provide insights for epidemic control in the context of the current serious situation worldwide. This study revealed that sporadic cases had lower levels of albumin and lymphocyte counts than family cluster cases; otherwise, there were no significant differences in terms of other epidemiological characters and clinical features between the two groups. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China doi = 10.1017/s0950268820001491 id = cord-346182-61i4jjys author = Myers, Jeffrey L title = Frontline Workers in the Backrooms of COVID-19: Caring for the Living and the Dead date = 2020-06-17 keywords = Michigan; covid-19; family summary = Through all of this, the forensics teams-pathologists, investigators, laboratory professionals, photographers, social workers, autopsy and pathologist assistants, and administrative staff-have been at the frontline of pathology''s largest COVID-19 front, contributing to the public welfare and the science of SARS-CoV-2 while caring for the dead and the living with a measure of compassion and kindness that few understand or know. During the COVID-19 pandemic, the forensic pathology program at the University of Michigan proved critical to supporting the counties they serve and families of the COVID-19 patients and others who died at home and in hospitals. Individuals in Michigan Medicine''s 4 county forensic services who died of conditions other than SARS-CoV-2 ❚Image 2❚ A large team at the Wayne County Medical Examiner''s Office in Detroit is responsible for autopsies each day and comprises a combination of Michigan Medicine staff (including pathologists'' assistants), trainees, and a faculty member who functions as officer of the day. doi = 10.1093/ajcp/aqaa106 id = cord-341265-esc55vwj author = Qiu, Jingwen title = Microbial enzymes catalyzing keratin degradation: Classification, structure, function date = 2020-08-05 keywords = Fig; enzyme; family; keratin; keratinolytic; protease summary = For example, family M28 and M3 proteases secreted from the non-pathogenic fungus Onygena corvina have been reported to catalyze degradation of pig bristle keratin, and moreover to act synergistically with enzymes from the S8 family . The keratinolytic enzymes in the different families may play different roles in the keratin degrading process, due to differences in their active sites, the preferred substrate cleavage sites and recognition of amino acid length. The family S9 exo-keratinases may play a key role in attacking products from endo-protease hydrolyzed keratin protein (Lange et al., 2016; Mercer and Stewart, 2019) , but is not highly efficient in directly degrading keratin. To obtain amino acids from keratin-rich materials using keratinolytic enzymes, a preliminary degradation of disulfide bonds is necessary to loosen the keratin structure and make the amino acid chains available for keratinase attack (Gupta et al., 2013b; Peng et al., 2019) . doi = 10.1016/j.biotechadv.2020.107607 id = cord-313887-8sabsrgy author = Quandt, Sara A. title = COVID-19 Pandemic among Latinx Farmworker and Nonfarmworker Families in North Carolina: Knowledge, Risk Perceptions, and Preventive Behaviors date = 2020-08-10 keywords = COVID-19; family; farmworker; sample summary = Taken together, the rapidly changing messages, coupled with public concern, and limited availability of up-to-date information in formats for those with limited English proficiency created a situation in the USA in which Latinx workers such as farmworkers were likely to lack consistent and accurate information and, as a result, practice ineffective behaviors to protect themselves and prevent spreading disease to their social network. This study was designed to describe the knowledge, perceived risk and susceptibility, and preventive behaviors reported by Latinx immigrant farmworker and nonfarmworker families in North Carolina during the first months of the COVID-19 pandemic. In total, these results indicate that, despite relatively high knowledge, strong perceptions of risk from COVID-19, and claims of avoiding situations where contracting or spreading infection might be likely, many of the farmworker families included here do not practice safe physical distancing measures as recommended; and their use of masks appears to be confined to work settings. doi = 10.3390/ijerph17165786 id = cord-291950-9gtsqyfj author = Rawlings, Neil D. title = Introduction: The Clans and Families of Cysteine Peptidases date = 2012-11-09 keywords = Cys; catalytic; chapter; endopeptidase; family; figure; peptidase summary = A non-peptidase homolog is known from Trypanosoma brucei in which the catalytic Cys has been replaced by Ser. Family C10 contains streptopain (Chapter 483) and a few similar enzymes, all of which are from gram-positive bacteria. An alignment shows that residues Gln31, Cys32, His95 and Asn113 are conserved, suggesting that the N-terminal domain is a cysteine peptidase with a papain-like fold, which we include in family C51. The ''papain-like'' endopeptidases of RNA viruses form a large group of cysteine peptidases that contain the catalytic dyad residues in the order Cys, His. All of the families had been included in clan CA, even though for many no tertiary structure for any member had been solved. Although no catalytic residues have been identified for any member of the family, they are predicted to occur in the order His, Glu, Gln, Cys. Family C57 contains the I7 protein from the vaccinia virus (Chapter 535), which is believed to be a polyprotein processing endopeptidase. doi = 10.1016/b978-0-12-382219-2.00404-x id = cord-012921-fvrculi6 author = Riedijk, S. R. title = A Decade of Genetic Counseling in Frontotemporal Dementia Affected Families: Few Counseling Requests and much Familial Opposition to Testing date = 2009-08-01 keywords = FTD; family; genetic summary = A decade of genetic counseling of frontotemporal dementia (FTD) affected families has generated two important observations. Second, FTD at-risk counselees reported substantial familial opposition to genetic testing, which is distinct from the attitude in Huntington Disease affected families. We hypothesize that the low acceptance for FTD genetic counseling is consequential to the familial opposition and explain this within the theoretical framework of separation-individuation. In addition, the geneticist provides technical information on the genetics of FTD, the phenotype and penetrance, whereas the psychosocial counselor explores in-depth the psychological make-up and motivation of the counselee and the family dynamics with regard to the hereditary disorder, and discusses how this counselee may best adapt to either test outcome. The low uptake for FTD genetic testing may result from a high prevalence of enmeshed family structures and its effects on separation-individuation processes. Through this discussion we aim to contribute to enhanced genetic counseling, testing and enriched psychological support of individuals at-risk for FTD and their families. doi = 10.1007/s10897-009-9222-3 id = cord-273140-etod8fgd author = Ritchey, Katherine C. title = Reinventing Palliative Care Delivery in the Era of COVID-19: How Telemedicine Can Support End of Life Care date = 2020-08-07 keywords = PCT; care; family summary = Products from this project included a standard operating procedure for safe use of tablet computers for inpatient palliative care consultations and family visitations; tablet procurement with installation of video telehealth software; and training and education for clinical staff and other stakeholders. The COVID-19 pandemic posed a threat to essential palliative care services, including building connections between patients, families, and healthcare teams; mitigating isolation, loneliness, and fear; managing symptoms; determining care priorities in the face of life threatening illness; and promoting comfort, connectedness and dignity during the dying process. This included procuring tablets that operated through guest wi-fi services and completing "test calls" confirming our ability to perform telehealth encounters throughout the facility; training PCT members in the use of VA and non-VA video conferencing platforms; and developing a facility-wide standard operating procedure (SOP) for the safe use of tablet computers for clinical video telehealth consultations and patient-family visitations for both inpatient Palliative Care Services and CLC Veterans (Supplemental Table 1 ). doi = 10.1177/1049909120948235 id = cord-346062-q0trgj12 author = Robert, René title = Ethical dilemmas due to the Covid-19 pandemic date = 2020-06-17 keywords = COVID-19; ICU; care; family; patient summary = The devastating pandemic that has stricken the worldwide population induced an unprecedented influx of patients in ICUs, raising ethical concerns not only surrounding triage and withdrawal of life support decisions, but also regarding family visits and quality of end-of-life support. As a result, four new options never applied to date were considered with the common aim of saving a maximum number of lives: to prioritize ICU beds for patients with the best prognosis; to increase at all costs the number of ICU beds, thereby creating stepdown ICUs; to organize transfer to distant ICUs with more beds available, or to accelerate withdrawal of life support in ICUs. Additionally, to protect the patients'' relatives, visits for families were prohibited or strongly limited and adequate communication between caregivers and families was disrupted, counteracting more than 20 years of research aimed at improving interaction with families and quality of care during EOL [1] . doi = 10.1186/s13613-020-00702-7 id = cord-025797-69siubkz author = Rogers, Amanda title = Patient and Family Centered (Tele)rounds: The use of video conferencing to maintain family and resident involvement in rounds date = 2020-06-02 keywords = Family summary = key: cord-025797-69siubkz cord_uid: 69siubkz Problem: Patient and Family Centered Rounds (PFCR) is an invaluable element of the care of a hospitalized child that has been shown to improve patient outcomes and trainee education. Initial modifications within our institution included a movement away from bedside PFCR and toward table rounds with asynchronous discussions. There was a concern these modifications excluded patients/families and decreased resident involvement in clinical management/communication which could negatively impact patient care and resident education. Modifications made based on feedback included ensuring teams were comfortable using technology, utilizing headphones to overcome difficulty hearing when wearing PPE helmets, and scripting that informed families about PFCT. We are also identifying ways PFCT could be utilized in the post Covid era including involving off-site team members and families that are not able to physically join rounds. Patient-and Family-Centered Care and the Pediatrician''s Role doi = 10.1016/j.acap.2020.05.026 id = cord-293822-axr9qu58 author = Rolland, John S. title = COVID‐19 Pandemic: Applying a Multi‐Systemic Lens date = 2020-07-17 keywords = COVID-19; family; member; pandemic; risk summary = Highlighting the pattern of psychosocial issues of COVID‐19 over time, discussion emphasizes the evolving interplay of larger systems public health pandemic challenges and mitigation strategies with individual and family processes. The paper addresses issues of coping with myriad Covid‐19 uncertainties in the initial crisis wave and evolving phases of the pandemic in the context of individual and family development, pre‐existing illness or disability, and racial and socioeconomic disparities. In addition to communication processes and organizational/structural patterns, particular emphasis includes: family and individual life course development in relation to the time phases of a disorder; multigenerational legacies related to illness and loss; and belief systems (including influences of culture, ethnicity, race, spirituality, and gender) (Figure 1 ). As the pandemic continues to evolve, these discussions will need to be revisited -relating to new COVID-19 data and to changing family circumstances, such as life cycle transitions or altered economic and health status. doi = 10.1111/famp.12584 id = cord-288673-ku3tmjd3 author = Sabotič, Jerica title = Microbial and fungal protease inhibitors—current and potential applications date = 2012-01-05 keywords = Barrett; Rawlings; Staphylococcus; cysteine; family; inhibitor; plant; protease; protein; target summary = Because proteases play essential roles in life and death processes in all living organisms and because peptide bond hydrolysis is irreversible, anomalies in proteolytic activities lead to numerous pathological conditions, including cancer, neurodegenerative disorders and inflammatory and cardiovascular diseases, as well as bacterial, viral and parasitic diseases (Lopez-Otin and Bond 2008; Turk 2006) . Another important oral cavity pathogen involved in periodontal disease, Porphyromonas gingivalis, in addition to a few cysteine proteases (discussed further in the following), produces a serine protease, a prolyl tripeptidyl peptidase PtpA (family S9), which is involved in degrading host connective tissue, providing nutrients for bacterial growth (Banbula et al. Several proteases of the serine catalytic type have also been targeted for the design of specific protease inhibitors for use in cancer treatment, including the urokinase plasminogen activator and matriptase (Abbenante and Fairlie 2005; Bialas and Kafarski 2009; Ulisse et al. doi = 10.1007/s00253-011-3834-x id = cord-339795-1bo38ooy author = Sano, Yoshie title = Well-Being and Stability among Low-income Families: A 10-Year Review of Research date = 2020-10-25 keywords = EITC; family; income; low summary = In the last decade, research on the economic security of lowincome families has centered around poverty dynamics, the effectiveness of welfare-to-work programs, employment issues, the Earned Income Tax Credit, and banking behavior. (2015) developed the Economic Well-Being Continuum (EWC) as a comprehensive measure to describe the circumstances of low-income families in eight specific dimensions (child care, employability, food security, health care security, housing security, transportation, reliance of assistance programs, and capabilities) and establish their level of economic functioning (persistently poor, struggling, and getting by). Employment issues â�¢ Rural low-income mothers remained in the same job because they utilized their limited resources effectively and developed strategies to combine work and family life including using social support network and supportive supervisors as well as flextime (Son and Bauer 2010) â�¢ Low-income mothers were more likely to be employed, especially full-time, if they were provided state childcare subsidy tied to their employment (Davis et al. doi = 10.1007/s10834-020-09715-7 id = cord-353410-tbmtg88k author = Sharma, Shreela V. title = Using a rapid assessment methodology to identify and address immediate needs among low-income households with children during COVID-19 date = 2020-10-01 keywords = Bites; COVID-19; family summary = Due to COVID-19-related school closures, states were under "shelter in place" orders, and Brighter Bites administered a rapid assessment survey to identify social needs among their families. While overall results of the qualitative thematic analysis for the n = 1048 participants are presented elsewhere (Sharma et al., under review) , a qualitative analysis of participant responses in the high-risk group revealed four major themes presented in Table 2 : fear of contracting COVID-19, disruption of employment status, financial hardship, and exacerbated food insecurity. Conducting a COVID-19 rapid response survey was a purposeful decision on part of Brighter Bites to identify those with highest need during this time of crisis and develop a framework to immediately address a variety of social needs among those in the "high risk" category. doi = 10.1371/journal.pone.0240009 id = cord-272772-zqmychmr author = Stall, Nathan M. title = Finding the Right Balance: An Evidence-Informed Guidance Document to Support the Re-Opening of Canadian Nursing Homes to Family Caregivers and Visitors during the COVID-19 Pandemic date = 2020-08-03 keywords = Care; covid-19; family summary = Canada, and regions across the country begin phased re-openings, experts and advocates have 24 grown increasingly concerned that subsequent visiting policies and family caregiver access to 25 nursing home settings remain overly restrictive, causing substantial and potentially irreversible 26 harm to the health and wellbeing of residents. 4 A more balanced approach is needed that both 27 prevents the introduction of COVID-19 into nursing homes, but also allows family caregivers 28 and visitors to provide much needed contact, support and care to residents, to maintain their 29 overall health and wellbeing. These recommendations 68 focus on family caregivers and general visitors rather than essential support workers and nursing 69 home staff, and are made with the acknowledgement that the approach to visiting may need to be 70 dynamic based on the community prevalence of COVID-19. doi = 10.1016/j.jamda.2020.07.038 id = cord-004373-nmnssoeb author = Wall, Jonathan T. title = What about lay counselors’ experiences of task-shifting mental health interventions? Example from a family-based intervention in Kenya date = 2020-02-20 keywords = Group; counselor; experience; family; role summary = We aimed to describe how lay counselors experience role shifts and associated outcomes, such as Keywords: Mental health, Lay counselors, Task shifting, Africa, Burnout, Motivation, Self-efficacy, Stress, Family therapy, Children Intrinsic and extrinsic forces, beliefs, and ideals that incline an individual to pursue and maintain their position as a lay counselor [22] An individual''s perceptions and assessments of their capability to be competent and effective in their counseling role [23] The physical, psychological, emotional, and social consequences that affect a lay counselor due to trying to fulfill the duties and responsibilities expected of them by their clients, supervisors, and communities Because the intervention was designed with the goal of minimizing the added burden for lay providers (described below), it offers a helpful lens and case study for understanding the specific contribution of role shifts in relation to other stressors associated with lay counselor experiences. doi = 10.1186/s13033-020-00343-0 id = cord-257813-2ij3fkrh author = Walsh, Froma title = Loss and Resilience in the Time of COVID‐19: Meaning Making, Hope, and Transcendence date = 2020-07-17 keywords = Walsh; family; life; loss; time summary = Applying a family resilience framework to pandemic‐related losses, discussion focuses on the importance of shared belief systems in (1) meaning‐making processes; (2) a positive, hopeful outlook and active agency; and (3) transcendent values and spiritual moorings for inspiration, transformation, and positive growth. A resilience-oriented approach with loss (a) contextualizes the distress; (b) attends to the challenges, suffering, and struggles of families, and (c) strengthens relational processes that support coping, adaptation, and growth. Family resilience is fostered by shared beliefs (1) to make meaning of the crisis and challenges; (2) to (re)gain a positive, hopeful outlook that supports active agency, and (3) for transcendence: to rise above suffering and hardship through larger values, spiritual beliefs and practices, and experiencing transformations in new priorities, a sense of purpose, and deeper bonds. In families, meaning-making processes involve shared attempts to make sense of the loss, put it in perspective to make it more bearable, and, over time, integrate it into personal and relational life passage (Nadeau, 2008) . doi = 10.1111/famp.12588 id = cord-352468-hi7u4w3q author = Xu, Xinglong title = Reconstructing family doctors’ psychological well-being and motivation for effective performance in China: the intervening role of psychological capital date = 2020-07-10 keywords = China; doctor; family; performance; psychological summary = In this paper, we apply a novel structural equation model to explore effect of interplay between psychological wellbeing, psychological capital and job involvement on family doctor motivation in Shanghai, Nanjing and Beijing in China. The model consisted of the latent variables psychological wellbeing, job involvement, the moderating variable (psychological capital and its constructs i.e. optimism, self-efficacy, resilience, hope) and the dependent variable (performance sustenance) among family doctors in China. The results of this study show that when psychological capital can interact with other job-related attitudes to generates positive and significant results thereby sustaining the performance of family doctors. This study intended to examine the relationship between job involvement, psychological well-being, and performance among family doctors in China. It again considered the influence of the interaction effect of psychological capital on psychological well-being, job involvement leading to performance sustenance on the family doctor system. doi = 10.1186/s12875-020-01182-1 id = cord-005147-mvoq9vln author = nan title = Autorenregister date = 2017-02-23 keywords = Berlin; Genetics; Germany; Human; Illumina; Institute; NGS; PCR; RNA; Sanger; University; WES; analysis; case; cell; disease; dna; expression; family; gene; mutation; patient; result; sequencing; study; syndrome; variant summary = Using whole-exome sequencing and trio-based de novo analysis, we identified a novel heterozygous de novo frameshift variant in the leukemia inhibitory factor receptor (LIFR) gene causing instability of the mRNA in a patient presenting with bilateral CAKUT and requiring kidney transplantation at one year of age. Loss of cdkl5 associated with deficient mammalian target of rapamycin (mTOR) signaling in mice and human cells We and other groups have shown that mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5) gene cause a severe neurodevelopmental disorder with clinical features including intellectual disability, early-onset intractable seizures and autism, that are closely related to those present in Rett syndrome (RTT) patients. Functional characterization of novel GNB1 mutations as a rare cause of global developmental delay Over the past years, prioritization strategies that combined the molecular predictors of sequence variants from exomes and genomes of patients with rare Mendelian disorders with computer-readable phenotype information became a highly effective method for detecting disease-causing mutations. doi = 10.1007/s11825-017-0126-6 id = cord-023647-dlqs8ay9 author = nan title = Sequences and topology date = 2003-03-21 keywords = Evolution; Family; Gene; Human; Protein; acid; sequence summary = Nucleotide Sequence Analysis of the L G~ne of Vesicular Stomafltia Virus (New Jersey Serotype) --Identification of Conserved Domai~L~ in L Proteins of Nonsegmented Negative-Strand RNA Viruses DERSE I~ Equine Infectious Anemia Virus tat--Insights into the Structure, Function, and Evolution of Lentivtrus tran.~Activator Proteins Ho~tu~ ~ s71 is a Ehylngcueticellly Distinct Human Endogenous Reteovtgal 1Rlement with Structural mad Sequence Homology to Simian Sarcoma Virus (SSV). Distinct Fercedoxins from Rhodobacter-Capsulstus -Complete Amino Acid Sequences and Molecular Evolution Complete Amino Acid Sequence and Homologies of Human Erythrocyte Membrane Protein Band 4.2. Identification of Two Highly Conserved Amino Acid Sequences Amon~ the ~x-subunits and Molecular ~ The Predicted Amino Acid Sequence of ct-lnternexin is that of a novel Neuronal lntegmedla~ ~ent Protein Inttaspecific Evolution of a Gene Family Coding for Urinary Proteins Attalysi~ of CDNA for Human ~ AJudgyrin I~dicltes a Repeated Structure with Homology to Tissue-Differentiation a~td Cell-Cycle Control Protein doi = 10.1016/0959-440x(91)90051-t id = cord-353438-6bx9lsc7 author = nan title = The COVID-19 Pandemic: A Family Affair date = 2020-05-19 keywords = family summary = Residents in long-term care facilities miss their partners and children who are no longer allowed to visit because of the COVID-19 policies to contain the spread of the coronavirus. Distressing stories abound of patients who have to deal with the news of their COVID-19 diagnosis all by themselves without a family member present and those patients who are admitted to an intensive care unit (ICU) who have to say goodbye to their family in the emergency department not knowing whether they will see each other again. Mothers, fathers, and other family members of children receiving psychiatric care report being unable visit their child for an extended period of time and are afraid their child will become ill from the coronavirus. Moreover, as a result of the COVID-19 crisis, much, if not all, of the support given to families who provide long-term care for an ill parent, partner, or child is lost. doi = 10.1177/1074840720920883