# ent

id: cord-010411-zgdvo29n
type: GGP
entity:
  Rev DOI 10 1007 s10567 020 00318 0 sha c3488a2180028698302ab604ff902d1dd78ce92a doc_id 10411 cord_uid zgdvo29n


id: cord-010411-zgdvo29n
type: ORG
entity:
  Pediatrics Business Roundtable Redefines the Purpose of a Corporation to Promote An Economy That Serves


id: cord-261424-t0yulofo
type: WORK_OF_ART
entity:
  Pediatrics A Pilot Study Utilizing Lean Principles to Improve Immunization Administration Efficiency


id: cord-261424-t0yulofo
type: ORG
entity:
  The Southern Illinoisan Department of Health Human Services Administration for Children and Families Administration on Children Youth and Families Child


id: cord-261424-t0yulofo
type: ORG
entity:
  Adverse Consequences of Rushing a SARS CoV 2 Vaccine Implications for Public Trust After Hurricane Floyd


id: cord-023647-dlqs8ay9
type: DNA
entity:
  Caisequestrin and Aspartactin Caisequestrin an Intesccilular Calciumbinding Protein of Skeletal Muscle Sarcoplssmic Reticulm Is HomoloKous to a Putstive latminin binding Protein


id: cord-023647-dlqs8ay9
type: DNA
entity:
  S t Anemone Anemom s ssdcmta and Its Evolutionary INtuition Amomqg Other Eukaryotes Inferred b om S l m Comlmrttmas


id: cord-023647-dlqs8ay9
type: PROTEIN
entity:
  Human Glycophorin A FlSP R P Drtmophila Proliferating Cell Nuclear Antigen Structural and Functional Homology


id: cord-023647-dlqs8ay9
type: PROTEIN
entity:
  Syrian Hamster Multifunctional Protein CAD Mammalian Dihydroorotase Nudeotide Sequence Peptide Sequences


id: cord-023647-dlqs8ay9
type: GGP
entity:
  Mdr P glycoprotein related ATP bindin g Protein Superfamlly A New Clam of Lym o real Vacuolar Protein Sorelng Signais l B Chem Complete Amino Acid Sequence


id: cord-023647-dlqs8ay9
type: WORK_OF_ART
entity:
  Vacuolar Protein Sorelng Signais l B Chem Complete Amino Acid Sequence and Homologies of Human Erythrocyte


id: cord-023647-dlqs8ay9
type: WORK_OF_ART
entity:
  Sequence and Homology to Thinredoxin Reductase and Other Fiavoprotein Disuliide Oxidoreducmses FC Nonuniform Evolution of Duplicated Developmentally Controlled C azrion Genes in a Sillumoth


id: cord-023647-dlqs8ay9
type: WORK_OF_ART
entity:
  of Bacteriophage Determine the Rate of Its Tt ansbttion Initiation Alternative MRNA Structures of the cm Genc of Bacta


id: cord-265323-urecb44o
type: WORK_OF_ART
entity:
  Dasien or Being in the World Dreyfus 2014 what Laotzu called the Tao or Way of Life Bynner 1944 and from a Christian perspective


id: cord-265323-urecb44o
type: WORK_OF_ART
entity:
  A Report of the American Psychological Association Task Force on the Interface Between Psychology Global Climate Change Most


id: cord-034464-yt5uyqb4
type: ORG
entity:
  1 American Family Business Survey 2 National Family Business Survey 3 Spatial Hazards and Losses Data


id: cord-263650-jxkjn8ld
type: DNA
entity:
  AMERICANS 11 2 75 79 2 65 69 3 Alzheimer s 7 mothers 5 With caregiver 1 9 0 1 75 79 1 pace maker 1 father 3 independently 10 19 2 2 80 84 2 diabetes 1 husband 3 nursing homes 20 29 1 1 85 89 1 prostate cancer 1 daughter


id: cord-280619-xcre2zgh
type: ORG
entity:
  the Qualifying Examination Royal College of Physicians and Surgeons of Canada Objectives of Training and


id: cord-293822-axr9qu58
type: DNA
entity:
  Coronavirus Disease 2019 COVID 19 Outbreak and Mental Health Current Risks and Recommended Actions For older people despair


id: cord-293822-axr9qu58
type: WORK_OF_ART
entity:
  The Coronavirus Disease 2019 COVID 19 Outbreak and Mental Health Current Risks and Recommended Actions


id: cord-288673-ku3tmjd3
type: PROTEIN
entity:
  metalloprotease griselysin family M4 Tight binding Laskowski Exclusive to bacterial Actinomycetales order


id: cord-288673-ku3tmjd3
type: CL
entity:
  Listeria monocytogenes coccolysin of Enterococcus faecalis hemagglutinin proteinase of Vibrio cholerae and Helicobycter pylori pseudolysin of Pseudomonas aeruginosa aureolysin


id: cord-288673-ku3tmjd3
type: GGP
entity:
  Staphylococcus aureus Legionella pneumophila protease and λ toxin of Clostridium perfringens Inhibitors


id: cord-333663-0yzrcfe5
type: ORG
entity:
  the Health Insurance Portability and Accountability Act Privacy Security and Breach Notification Rules HIPAA Rules


id: cord-339795-1bo38ooy
type: ORG
entity:
  Supplemental Nutrition Assistance Program SNAP Special Supplemental Nutrition Program for Women Infants and Children WIC


id: cord-272772-zqmychmr
type: ORG
entity:
  LTCcovid International Long Term Care Policy Network Ontario Ministries of Health and Long Term Care COVID 19


id: cord-353410-tbmtg88k
type: ORG
entity:
  the Special Supplemental Nutrition Program for Women Infants and Children WIC Supplemental Nutrition Assistance Program SNAP


id: cord-353410-tbmtg88k
type: ORG
entity:
  Development of Rapid Epidemiologic Assessment Methods to Evaluate Health Status and Delivery of Health Service Development


id: cord-341265-esc55vwj
type: PROTEIN
entity:
  M32 carboxypeptidases subfamily I e g Thermus aquaticus TaqCP Pyrococcus furiosus PfuCP Leishmania major LmaCP


id: cord-341265-esc55vwj
type: GGP
entity:
  thioredoxin reductase EC 1 8 1 9 dihydrolipoyl dehydrogenase EC 1 8 1 4 peptide methionine sulfoxide reductase EC 1 8 4 11 J o u r n a l P r e p r o o f


id: cord-341265-esc55vwj
type: DISEASE
entity:
  Bacillus subtilis RSE163 Purification and biochemical characterization of a detergent stable keratinase


id: cord-005147-mvoq9vln
type: DNA
entity:
  chromosomes 13q12 rs7329408 near FLT1 POMP SLC46A3 P 9 41 10 16 11q23 3 rs11827818 near TMEM136 ARHGEF12 P 1 21 10 10 6p21 rs3130283


id: cord-005147-mvoq9vln
type: DNA
entity:
  breakpoint flanking regions M Hillmer 1 2 A Summerer 1 2 V F Mautner 3 4 L Messiaen 5 6 H 2 1 Institute


id: cord-005147-mvoq9vln
type: PROTEIN
entity:
  nuclear envelope P Meinke S Hintze S Limmer B Schoser Friedrich Baur Institute Munich Germany Myotonic dystrophies DM


id: cord-005147-mvoq9vln
type: DNA
entity:
  BRCA1 2 mutation negative HBOC n 158 or early onset sporadic breast cancer patients n 8 for variants


id: cord-005147-mvoq9vln
type: CELL_LINE
entity:
  multi parameter magnetic activated cell sorting MACS technique CD15 and CD133 labeled cell subpopulations


id: cord-005147-mvoq9vln
type: PROTEIN
entity:
  KCNJ4 Mundlos 1 2 4 D Horn 1 M Spielmann 1 2 4 1 Institute for Medical Genetics and Human Genetics Charité Universitätsmedizin Berlin Berlin Germany 2


id: cord-005147-mvoq9vln
type: GGP
entity:
  E G Dekomien 1 2 B Bellenberg 2 3 N Trampe 2 4 R Schneider 2 4 C Prehn 2 4 C Krogias 2 4 R Kropatsch 1 2


id: cord-005147-mvoq9vln
type: WORK_OF_ART
entity:
  A M Nissen J Graf C Rapp M Locher A Laner A Benet Pagès E Holinski Feder Medizinisch Genetisches Zentrum


id: cord-005147-mvoq9vln
type: ORG
entity:
  Cancer Science Institute of Singapore National University of Singapore Singapore 4 Institute of Molecular Biology


id: cord-005147-mvoq9vln
type: ORG
entity:
  TSC C Müller Hofstede J Horvath B Dworniczak P Wieacker Institute of Human Genetics University of Münster Germany


id: cord-005147-mvoq9vln
type: DISEASE
entity:
  gastrointestinal system small intestine liver pancreas the genito urinary system kidney testis spermatozoa prostate the respiratory system lung smooth muscle


id: cord-005147-mvoq9vln
type: DISEASE
entity:
  cardiac valves after valve formation High resolution digital echocardiography showed that mice without Adamts19 expression develop dysfunctional aortic valves


id: cord-005147-mvoq9vln
type: DISEASE
entity:
  attention deficit hyperactivity disorder ADHD anorexia nervosa anxiety disorders autism spectrum disorder bipolar disorder


id: cord-005147-mvoq9vln
type: CHEMICAL
entity:
  E G Dekomien 1 2 B Bellenberg 2 3 N Trampe 2 4 R Schneider 2 4 C Prehn 2 4 C Krogias 2 4 R Kropatsch 1 2 M Regensburger 5 6 C Lukas 2 3 R Gold 2 4 4 1 Human


id: cord-005147-mvoq9vln
type: CHEMICAL
entity:
  Mautner 3 4 L Messiaen 5 6 H 2 1 Institute of Human Genetics Ulm Germany 2 University of Ulm Ulm Germany 3 Department of


id: cord-005147-mvoq9vln
type: DISEASE
entity:
  prostatic carcinoma thyroid carcinoma colorectal cancer gastric carcinoma leukemia cervical carcinoma


id: cord-353438-6bx9lsc7
type: ORG
entity:
  Birte Østergaard PhD Associate Professor Department of Clinical Research University of Southern Denmark Denmark Email


id: cord-354194-hf5ndv5f
type: ORG
entity:
  the American Association for the Surgery of Trauma Critical Care Societies Collaborative UTFoCCR Multisociety Task Force for Critical Care Research


# bib

id: cord-004373-nmnssoeb
author: Wall, Jonathan T.
date: 2020-02-20
txt: ./txt/cord-004373-nmnssoeb.txt
cache: ./cache/cord-004373-nmnssoeb.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031864/
doi: 10.1186/s13033-020-00343-0
summary:
  We aimed to describe how lay counselors experience role shifts and associated outcomes, such as Keywords: Mental health, Lay counselors, Task shifting, Africa, Burnout, Motivation, Self-efficacy, Stress, Family therapy, Children Intrinsic and extrinsic forces, beliefs, and ideals that incline an individual to pursue and maintain their position as a lay counselor [22] An individual''s perceptions and assessments of their capability to be competent and effective in their counseling role [23] The physical, psychological, emotional, and social consequences that affect a lay counselor due to trying to fulfill the duties and responsibilities expected of them by their clients, supervisors, and communities Because the intervention was designed with the goal of minimizing the added burden for lay providers (described below), it offers a helpful lens and case study for understanding the specific contribution of role shifts in relation to other stressors associated with lay counselor experiences.

title:
  What about lay counselors’ experiences of task-shifting mental health interventions? Example from a family-based intervention in Kenya

abstract:
  BACKGROUND: A key focus of health systems strengthening in low- and middle-income countries is increasing reach and access through task-shifting. As such models become more common, it is critical to understand the experiences of lay providers because they are on the forefront for delivering care services. A greater understanding would improve lay provider support and help them provide high-quality care. This is especially the case for those providing mental health services, as providing psychological care may pose unique stressors. We sought to understand experiences of lay counselors, focusing on identity, motivation, self-efficacy, stress, and burnout. The goal was to understand how taking on a new provider role influences their lives beyond simply assuming a new task, which would in turn help identify actionable steps to improve interventions with task-shifting components. METHODS: Semi-structured interviews (n = 20) and focus group discussions (n = 3) were conducted with three lay counselor groups with varying levels of experience delivering a community-based family therapy intervention in Eldoret, Kenya. Thematic analysis was conducted, including intercoder reliability checks. A Stress Map was created to visualize stress profiles using free-listing and pile-sorting data collected during interviews and focus group discussions. RESULTS: Counselors described high intrinsic motivation to become counselors and high self-efficacy after training. They reported positive experiences in the counselor role, with new skills improving their counseling and personal lives. As challenges arose, including client engagement difficulties and balancing many responsibilities, stress and burnout increased, dampening motivation and self-efficacy. In response, counselors described coping strategies, including seeking peer and supervisor support, that restored their motivation to persevere. At case completion, they again experienced high self-efficacy and a desire to continue. CONCLUSIONS: Findings informed suggestions for ways to incorporate support for lay providers into task-shifting interventions at initiation, during training, and throughout implementation. These include acknowledging and preparing counselors for challenges during training, increasing explicit attention to counselor stress in supervision, fostering peer support among lay providers, and ensuring a fair balance between workload and compensation. Improving and building an evidence base around practices for supporting lay providers will improve the effectiveness and sustainability of lay provider-delivered interventions.


id: cord-005147-mvoq9vln
title: Autorenregister
author: nan
date: 2017-02-23
txt: ./txt/cord-005147-mvoq9vln.txt
cache: ./cache/cord-005147-mvoq9vln.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088617/
doi: 10.1007/s11825-017-0126-6
abstract: nan
summary:
  Using whole-exome sequencing and trio-based de novo analysis, we identified a novel heterozygous de novo frameshift variant in the leukemia inhibitory factor receptor (LIFR) gene causing instability of the mRNA in a patient presenting with bilateral CAKUT and requiring kidney transplantation at one year of age. Loss of cdkl5 associated with deficient mammalian target of rapamycin (mTOR) signaling in mice and human cells We and other groups have shown that mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5) gene cause a severe neurodevelopmental disorder with clinical features including intellectual disability, early-onset intractable seizures and autism, that are closely related to those present in Rett syndrome (RTT) patients. Functional characterization of novel GNB1 mutations as a rare cause of global developmental delay Over the past years, prioritization strategies that combined the molecular predictors of sequence variants from exomes and genomes of patients with rare Mendelian disorders with computer-readable phenotype information became a highly effective method for detecting disease-causing mutations.


id: cord-006934-92ctgc4n
title: Families and clans of cysteine peptidases
author: Barrett, Alan J.
date: 1996
txt: ./txt/cord-006934-92ctgc4n.txt
cache: ./cache/cord-006934-92ctgc4n.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104565/
doi: 10.1007/bf02174042
summary:
  In all the cysteine peptidases discovered so far, the activity depends upon a catalytic dyad, the second member of which is a histidine residue acting as a general base. The amino acid sequences of the cysteine peptidases of picornaviruses (picornains 2A and 3C) (family C3) hint at a relationship with chymotrypsin [34] , and when the threedimensional structure of picornain 3C from the human hepatitis A virus was determined, it showed unmistakable similarities to that of chymotrypsin and other members of clan SA [6, 35] . There are additionally many polyprotein processing endopeptidases from RNA viruses that have the Cys/His catalytic dyad, and also show the bulky hydrophobic amino acid following the catalytic cysteine that is characteristic of the papain clan. The three-dimensional structure of interleukin-l[3-converting enzyme shows a distinctive protein fold, and thus a separate origin for this group of cysteine peptidases [7, 8] .

abstract:
  The known cysteine peptidases have been classified into 35 sequence families. We argue that these have arisen from at least five separate evolutionary origins, each of which is represented by a set of one or more modern-day families, termed a clan. Clan CA is the largest, containing the papain family, C1, and others with the Cys/His catalytic dyad. Clan CB (His/Cys dyad) contains enzymes from RNA viruses that are distantly related to chymotrypsin. The peptidases of clan CC are also from RNA viruses, but have papain-like Cys/His catalytic sites. Clans CD and CE contain only one family each, those of interleukin-1β-converting enzyme and adenovirus L3 proteinase, respectively. A few families cannot yet be assigned to clans. In view of the number of separate origins of enzymes of this type, one should be cautious in generalising about the catalytic mechanisms and other properties of cysteine peptidases as a whole. In contrast, it may be safer to generalise for enzymes within a single family or clan.


id: cord-010411-zgdvo29n
author: Biglan, Anthony
date: 2020-04-28
txt: ./txt/cord-010411-zgdvo29n.txt
cache: ./cache/cord-010411-zgdvo29n.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186188/
doi: 10.1007/s10567-020-00318-0
summary:
  As noted above, schools in high poverty neighborhoods and communities have higher rates of punitive practices and fewer resources for preventing the development of problem behavior (American Psychological Association, n.d.). Given the extent of discrimination in the USA, its impact on public health, and the size of the workforce, it is imperative that foundations and the NIH fund research to identify more effective ways to reduce prejudice in schools, work settings, and neighborhoods and communities. While it is true that addressing the above-described contextual conditions is likely to improve family well-being significantly, it is unlikely that reducing problems like poverty and discrimination will ensure that every family and school adopt the most effective ways of nurturing children''s development . Evidence of the value of both economic development efforts and programs targeting families and schools suggests it is time to test comprehensive interventions that simultaneously address all risk factors for problems for which we have some effective solutions.

title:
  A Strategic Plan for Strengthening America’s Families: A Brief from the Coalition of Behavioral Science Organizations

abstract:
  Despite significant progress in research on the treatment and prevention of psychological, behavioral, and health problems, the translation of this knowledge into population-wide benefit remains limited. This paper reviews the state of America’s children and families, highlighting the influence of stressful contextual and social conditions on child and family well-being and the concentration of disadvantage in numerous neighborhoods and communities throughout the nation. It then briefly reviews the progress that has been made in pinpointing policies that can reduce stressful contextual conditions such as poverty, discrimination, and the marketing of unhealthful foods and substances. It also describes numerous family and school interventions that have proven benefit in preventing psychological and behavioral problems as diverse as tobacco, alcohol, and other drug use; depression; antisocial behavior; academic failure; obesity prevention; and early childbearing. We argue that progress in translating existing knowledge into widespread benefit will require a nationwide effort to intervene comprehensively in neighborhoods and communities of concentrated disadvantage. We present a strategic plan for how such an effort could be organized. The first step in this organizing would be the creation of a broad and diverse coalition of organizations concerned with advancing public health and well-being. Such a coalition could increase public support both for the policies needed to focus on these disadvantaged areas and the research needed to incrementally improve our ability to help these areas.


id: cord-010837-8x3bch0r
author: Curran, Janet A.
date: 2020-05-14
txt: ./txt/cord-010837-8x3bch0r.txt
cache: ./cache/cord-010837-8x3bch0r.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222504/
doi: 10.1186/s12887-020-02117-6
summary:
  In Phase 2, pediatricians, nurses, and health administrators participated in key stakeholder interviews to identify barriers and facilitators to a successful transition in care for children and families with complex care needs. (2) other parents on the inpatient unit act as key supports to the family; (3) satisfaction with the care from the local community pediatrician, but dissatisfaction with care received from the community hospital following misplacement of the child''s feeding tube; (4) an advanced practice nurse guiding the discharge process and using a locally developed tool to guide discharge planning that was distributed to the family and home community to promote continuity of care; (5) a high level of engagement from the family helping to facilitate a smooth transition as reported by the health care team; and (6) a lack of pediatric expertise in community physiotherapy.

title:
  Improving transitions in care for children with complex and medically fragile needs: a mixed methods study

abstract:
  BACKGROUND: Children with medical complexity are a small yet resource intensive population in the Canadian health care system. The process for discharging these children from hospital to home is not yet optimal. The overall goal of this project was to develop recommendations to be included in a provincial strategy to support transitions in care for children with complex and medically fragile needs. METHODS: A wide assortment of stakeholders participated in this mixed method, multiphase project. During Phase 1, data was gathered from a range of sources to document families’ experiences transitioning from an inpatient hospital stay back to their home communities. In Phase 2, pediatricians, nurses, and health administrators participated in key stakeholder interviews to identify barriers and facilitators to a successful transition in care for children and families with complex care needs. A multi-sector consensus meeting was held during Phase 3 to discuss study findings and refine key recommendations for inclusion in a provincial strategy. RESULTS: Six case studies were developed involving children and families discharged home with a variety of complex care needs. Children ranged in age from 15 days to 9 years old. Nine telephone interviews were conducted in Phase 2 with pediatricians, nurses, and administrators from across the province. A variety of inter-institutional communication challenges were described as a major barrier to the transition process. A consistent message across all interviews was the need for improved coordination to facilitate transitions in care. The consensus meeting to review study findings included physicians, nurses, paramedics, senior administrators, and policy analysts from different health and government sectors and resulted in six recommendations for inclusion in a provincial strategy. CONCLUSIONS: This project identified policy and practice gaps that currently exist related to transitions in care for children with complex and medically fragile needs and their families. Our collaborative patient-centred approach to understanding how children and families currently navigate transitions in care provided a foundation for developing recommendations for a provincial wide strategy.


id: cord-012387-1ogcxd7b
title: The political consequences of opioid overdoses
author: Kaufman, Aaron R.
date: 2020-08-04
txt: ./txt/cord-012387-1ogcxd7b.txt
cache: ./cache/cord-012387-1ogcxd7b.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402477/
doi: 10.1371/journal.pone.0236815
summary:
  This paper applies a validated causal research design to study the political consequences of the opioid epidemic on the individuals closest to it-the friends and family of overdose victims. In contrast to other studies examining the effects of tragedy on political participation, we find that friends and family of opioid overdose victims are less likely to turn out to vote than they were before tragedy struck, even compared to victims of premature cancer or a demographically-matched sample of registrants without familial opioid overdoses. We identify in public voter registration records the friends and family of opioid overdose victims, and compare their election turnout rates and party identification in the elections immediately before and after their loved one''s death. By comparing political behaviors of these matched groups to the original samples of family members, we control for all observed (but not unobserved) factors that might confound the relationship between cancer or opioid overdose deaths and voter turnout.

abstract:
  The United States suffered a dramatic and well-documented increase in drug-related deaths from 2000 to 2018, primarily driven by prescription and non-prescription opioids, and concentrated in white and working-class areas. A growing body of research focuses on the causes, both medical and social, of this opioid crisis, but little work as yet on its larger ramifications. Using novel public records of accidental opioid deaths linked to behavioral political outcomes, we present causal analyses showing that opioid overdoses have significant political ramifications. Those close to opioid victims vote at lower rates than those less affected by the crisis, even compared to demographically-similar friends and family of other unexpected deaths. Moreover, among those friends and family affected by opioids, Republicans are 25% more likely to defect from the party than the statewide average Republican, while Democrats are no more likely to defect; Independents are moderately more likely to register as Democrats. These results illustrate an important research design for inferring the effects of tragic events and speak to the broad social and political consequences of what is becoming the largest public health crisis in modern United States history.


id: cord-012921-fvrculi6
author: Riedijk, S. R.
date: 2009-08-01
txt: ./txt/cord-012921-fvrculi6.txt
cache: ./cache/cord-012921-fvrculi6.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706981/
doi: 10.1007/s10897-009-9222-3
summary:
  A decade of genetic counseling of frontotemporal dementia (FTD) affected families has generated two important observations. Second, FTD at-risk counselees reported substantial familial opposition to genetic testing, which is distinct from the attitude in Huntington Disease affected families. We hypothesize that the low acceptance for FTD genetic counseling is consequential to the familial opposition and explain this within the theoretical framework of separation-individuation. In addition, the geneticist provides technical information on the genetics of FTD, the phenotype and penetrance, whereas the psychosocial counselor explores in-depth the psychological make-up and motivation of the counselee and the family dynamics with regard to the hereditary disorder, and discusses how this counselee may best adapt to either test outcome. The low uptake for FTD genetic testing may result from a high prevalence of enmeshed family structures and its effects on separation-individuation processes. Through this discussion we aim to contribute to enhanced genetic counseling, testing and enriched psychological support of individuals at-risk for FTD and their families.

title:
  A Decade of Genetic Counseling in Frontotemporal Dementia Affected Families: Few Counseling Requests and much Familial Opposition to Testing

abstract:
  A decade of genetic counseling of frontotemporal dementia (FTD) affected families has generated two important observations. First, the uptake rate for presymptomatic testing for FTD is low in our department of Clinical Genetics at the Erasmus Medical Center in the Netherlands. Second, FTD at-risk counselees reported substantial familial opposition to genetic testing, which is distinct from the attitude in Huntington Disease affected families. We hypothesize that the low acceptance for FTD genetic counseling is consequential to the familial opposition and explain this within the theoretical framework of separation-individuation. Furthermore, we hypothesize that separation-individuation problems do not similarly influence the acceptance of HD genetic counseling, due to the educative role of the well-organised patient organization for HD in the Netherlands. We offer counseling recommendations that serve to facilitate the individuation of the counselee with respect to the FTD genetic test.


id: cord-013286-5lxy8qrq
author: Bolarinwa, Obasanjo A.
date: 2020-09-18
txt: ./txt/cord-013286-5lxy8qrq.txt
cache: ./cache/cord-013286-5lxy8qrq.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564680/
doi: 10.4102/phcfm.v12i1.2552
summary:
  Aim: This study aimed to identify and analyse the factors associated with the low use of contraceptives amongst vulnerable women in the South West region in Nigeria. Aim: This study aimed to identify and analyse the factors associated with the low use of contraceptives amongst vulnerable women in the South West region in Nigeria. 22 Hence, there are critical needs to examine the family type, living arrangement and contraceptive use amongst vulnerable mothers in South West, Nigeria. The study was quantitative research, which employed a cross-sectional descriptive survey design to elicit information on family planning use, family types and living arrangements amongst vulnerable mothers in Osun State, Nigeria using a structured questionnaire. Although the prevalence level of contraceptive use amongst sexually active men and women is low in Nigeria, 8, 10, 20 we studied variations by living arrangements and family types in the use of any family planning method amongst young mothers.

title:
  Factors associated with low contraceptive use amongst vulnerable mothers in South West State, Nigeria

abstract:
  BACKGROUND: Young mothers tend to be more prone to high maternal and perinatal risks and are thus deemed vulnerable to adverse sexual and reproductive health rights (SRHR) in terms of their right to choose contraceptives of their choice to enhance their maternal well-being and childbirth spacing should be well discussed. Achieving sufficient SRHR may be averted if the use of family planning by disadvantaged groups is not given required attention. AIM: This study aimed to identify and analyse the factors associated with the low use of contraceptives amongst vulnerable women in the South West region in Nigeria. SETTING: The study area was purposively chosen to capture contraceptive use amongst vulnerable women in Osun State, Nigeria. METHODS: A primary data collection was done in three senatorial districts of Osun State, Nigeria, with 140 respondents each to give a total of 420 respondents. Collected data were analysed using univariate, bivariate and multivariate measures. RESULTS: The result showed a magnitude of association and relationship at both levels of analyses. Living arrangements and family types were 89% and 88.3%, respectively, associated with family planning use. In the same vein, living arrangement and family types were also statistically significant at p < 0.05with an odds ratio of 0.23 (95% CI: 0.1184–0.4583) and an odds ratio of 0.35 (95% CI: 0.1756–0.6970) with family planning use, respectively. CONCLUSION: We concluded that policies and interventions to accelerate and encourage contraceptives use amongst vulnerable mothers in South West, Nigeria should be targeted at those whose husbands lived elsewhere and those whose husbands have more than one wife.


id: cord-023647-dlqs8ay9
title: Sequences and topology
author: nan
date: 2003-03-21
txt: ./txt/cord-023647-dlqs8ay9.txt
cache: ./cache/cord-023647-dlqs8ay9.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173161/
doi: 10.1016/0959-440x(91)90051-t
abstract: nan
summary:
  Nucleotide Sequence Analysis of the L G~ne of Vesicular Stomafltia Virus (New Jersey Serotype) --Identification of Conserved Domai~L~ in L Proteins of Nonsegmented Negative-Strand RNA Viruses DERSE I~ Equine Infectious Anemia Virus tat--Insights into the Structure, Function, and Evolution of Lentivtrus tran.~Activator Proteins Ho~tu~ ~ s71 is a Ehylngcueticellly Distinct Human Endogenous Reteovtgal 1Rlement with Structural mad Sequence Homology to Simian Sarcoma Virus (SSV). Distinct Fercedoxins from Rhodobacter-Capsulstus -Complete Amino Acid Sequences and Molecular Evolution Complete Amino Acid Sequence and Homologies of Human Erythrocyte Membrane Protein Band 4.2. Identification of Two Highly Conserved Amino Acid Sequences Amon~ the ~x-subunits and Molecular ~ The Predicted Amino Acid Sequence of ct-lnternexin is that of a novel Neuronal lntegmedla~ ~ent Protein Inttaspecific Evolution of a Gene Family Coding for Urinary Proteins Attalysi~ of CDNA for Human ~ AJudgyrin I~dicltes a Repeated Structure with Homology to Tissue-Differentiation a~td Cell-Cycle Control Protein


id: cord-025797-69siubkz
author: Rogers, Amanda
date: 2020-06-02
txt: ./txt/cord-025797-69siubkz.txt
cache: ./cache/cord-025797-69siubkz.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265834/
doi: 10.1016/j.acap.2020.05.026
abstract: nan
summary:
  key: cord-025797-69siubkz cord_uid: 69siubkz Problem: Patient and Family Centered Rounds (PFCR) is an invaluable element of the care of a hospitalized child that has been shown to improve patient outcomes and trainee education. Initial modifications within our institution included a movement away from bedside PFCR and toward table rounds with asynchronous discussions. There was a concern these modifications excluded patients/families and decreased resident involvement in clinical management/communication which could negatively impact patient care and resident education. Modifications made based on feedback included ensuring teams were comfortable using technology, utilizing headphones to overcome difficulty hearing when wearing PPE helmets, and scripting that informed families about PFCT. We are also identifying ways PFCT could be utilized in the post Covid era including involving off-site team members and families that are not able to physically join rounds. Patient-and Family-Centered Care and the Pediatrician''s Role

title:
  Patient and Family Centered (Tele)rounds: The use of video conferencing to maintain family and resident involvement in rounds


id: cord-034464-yt5uyqb4
title: Family business research: Reviewing the past, contemplating the future
author: Haynes, George
date: 2020-10-31
txt: ./txt/cord-034464-yt5uyqb4.txt
cache: ./cache/cord-034464-yt5uyqb4.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599979/
doi: 10.1007/s10834-020-09732-6
summary:
  In the future, family business researchers have the opportunity to better understand the impact of community resources and climate; more carefully assess the challenges of women, minorities, and immigrants; understand the role of cultural capital; and explore the impact of innovation during rapidly changing times, such as those created by the pandemic. The foundation provided by Yilmazer and Schrank (2010) was important in the development of a research study by McDonald and Marshall (2018) , which used Sustainable Family Business Theory (SFBT) and Intergeneration Family Business Survey data. Based on suggestions by Yilmazer and Schrank (2010) , household and business economic research in the JFEI explored the importance of cash flow, profitability, and savings in supporting family business well-being, satisfaction, success, and survival. The JFEI literature explored adjustment strategies employed by women and minority family business owners during hectic times; and, considered the importance of capital use and innovative technologies in managing the firm.

abstract:
  This paper reviews articles published in the Journal of Family and Economic Issues (JFEI) from 2010 to 2019 and considers future research opportunities. The JFEI articles utilize theories and conceptual frameworks from several social science fields, to help readers understand the importance of including both the family and business in any discussion of family businesses. The literature review addresses four family business topical areas: (1) household and business economics, (2) business continuity and succession, (3) managerial and adoption strategies, and (4) values and goals. These JFEI articles have focused on differentiating family businesses from other types of businesses; explaining the unique interface between the family and the business; and identifying the characteristics (i.e., demographics, adjustment strategies, continuity, capitals, and values and goals) for family business survival and success. In the future, family business researchers have the opportunity to better understand the impact of community resources and climate; more carefully assess the challenges of women, minorities, and immigrants; understand the role of cultural capital; and explore the impact of innovation during rapidly changing times, such as those created by the pandemic.


id: cord-257813-2ij3fkrh
title: Loss and Resilience in the Time of COVID‐19: Meaning Making, Hope, and Transcendence
author: Walsh, Froma
date: 2020-07-17
txt: ./txt/cord-257813-2ij3fkrh.txt
cache: ./cache/cord-257813-2ij3fkrh.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pubmed/32678915/
doi: 10.1111/famp.12588
summary:
  Applying a family resilience framework to pandemic‐related losses, discussion focuses on the importance of shared belief systems in (1) meaning‐making processes; (2) a positive, hopeful outlook and active agency; and (3) transcendent values and spiritual moorings for inspiration, transformation, and positive growth. A resilience-oriented approach with loss (a) contextualizes the distress; (b) attends to the challenges, suffering, and struggles of families, and (c) strengthens relational processes that support coping, adaptation, and growth. Family resilience is fostered by shared beliefs (1) to make meaning of the crisis and challenges; (2) to (re)gain a positive, hopeful outlook that supports active agency, and (3) for transcendence: to rise above suffering and hardship through larger values, spiritual beliefs and practices, and experiencing transformations in new priorities, a sense of purpose, and deeper bonds. In families, meaning-making processes involve shared attempts to make sense of the loss, put it in perspective to make it more bearable, and, over time, integrate it into personal and relational life passage (Nadeau, 2008) .

abstract:
  This article addresses the many complex and traumatic losses wrought by the COVID‐19 pandemic. In contrast to individually‐based, symptom‐focused grief work, a resilience‐oriented, systemic approach with complex losses contextualizes the distress and mobilizes relational resources to support positive adaptation. Applying a family resilience framework to pandemic‐related losses, discussion focuses on the importance of shared belief systems in (1) meaning‐making processes; (2) a positive, hopeful outlook and active agency; and (3) transcendent values and spiritual moorings for inspiration, transformation, and positive growth. Practice guidelines are offered to facilitate adaptation and resilience.


id: cord-261424-t0yulofo
author: Feltman, Dalia M.
date: 2020-06-26
txt: ./txt/cord-261424-t0yulofo.txt
cache: ./cache/cord-261424-t0yulofo.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pubmed/32599031/
doi: 10.1016/j.jpeds.2020.06.067
abstract: nan
summary:
  Pediatricians around the world have cycled through these emotions when considering the health and safety of patients and families during this coronavirus disease 2019 (COVID19) pandemic. As advocates for children, pediatricians are in a unique position to redesign the system in a way that prioritizes children and families, addresses the social determinants of health, reduces inequalities and health disparities, and ensures ethical research on treatment and prevention of COVID-19. However, actions to conserve the medical resources that prevent iatrogenic spread of infection and protect health professionals and other patients have shifted priorities away from the best practices that are part of our usual care for children. As we begin to imagine that new normal, we consider three domains that require attention to help children to stay well: medical, mental health, and educational needs. Children in families with mental health needs will be vulnerable to further disruptions to their psychosocial stability due to COVID-19 control measures.

title:
  Seeking Normalcy as the Curve Flattens: Ethical Considerations for Pediatricians Managing Collateral Damage of COVID-19


id: cord-263650-jxkjn8ld
title: Family care across diverse cultures: Re-envisioning using a transnational lens
author: Andruske, Cynthia Lee
date: 2020-10-20
txt: ./txt/cord-263650-jxkjn8ld.txt
cache: ./cache/cord-263650-jxkjn8ld.txt
extension: .txt
mime: text/plain
url: https://www.sciencedirect.com/science/article/pii/S0890406520300621
doi: 10.1016/j.jaging.2020.100892
summary:
  Specifically, drawing on a broad understanding of care that is consistent with Fisher and Tronto (1990) ; also Tronto, 2013) , the purpose of our study was to explore and compare the relationships between culture and informal family care practices across three diverse ethno-cultural groups: Chinese, South Asians, and Latin Americans living in Vancouver, British Columbia, Canada. Adults self-identifying as Chinese, South Asian, and Latin American, and providing unpaid, informal care or support to someone over the age of 65 needing some level of assistance with activities of daily living, were invited to participate. Even only adult children like Argentinian Rossana pointed out that she had created networks from her family (husband, daughter, and grandchildren, among others) and paid companions as well as her 92-year-old mother''s long-time friends to provide support and care.

abstract:
  In an increasingly globalized world, the importance of developing a more culturally complex understanding of family care has been clearly identified. This study explored family care across three different cultural groups - Chinese, South Asian, and Latin American - living in a metropolitan, Pacific-West, Canadian city. In-depth qualitative interviews were conducted with 29 family members from one of the three family groups exploring how they practiced ‘care’ for their aging, often frail, relatives. The importance of conceptualizing family care as a transnational, collective undertaking emerged from the outset as critical for understanding care practices in all three cultural communities. Three themes identified contributed to this conceptualization: the need to broaden the understanding of family care; the centrality of geographic mobility, and the need to rethink the location of aging and consider its relationship to mobility; and the use of technology by extended family networks to facilitate continuity and connection. An over-riding notion of ‘flow’ or fluid movement, rather than a fixed, static arrangement, emerged as critical for understanding family care. This perspective challenges the dominant approach to studying family care in gerontology that generally conceptualizes family care practice as one local primary caregiver, often female, with some support from other family members. Understanding family care from a transnational lens builds support for the importance of a feminist Ethics of Care lens and has important implications for policy and service delivery practices.


id: cord-265323-urecb44o
title: Reaching Up, Down, In, and Around: Couple and Family Coping During the Corona Virus Pandemic
author: Fraenkel, Peter
date: 2020-06-26
txt: ./txt/cord-265323-urecb44o.txt
cache: ./cache/cord-265323-urecb44o.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.1111/famp.12570
doi: 10.1111/famp.12570
summary:
  Challenges include Illness, death, and the fears thereof; employment and economic losses the growing evidence of heath care disparities between persons of differing social locations in terms of race, ethnicity, socioeconomic status, profession, and citizenship status; fears of losing housing, access to food and other basic needs; lack of consistent information about the level of risk of infection or guidance about best practices to reduce that risk; the need to quarantine with partners and family members despite conflicts that are usually mitigated somewhat by daily distance through going to work and school, and on the other hand, interminable separations between family members, friends, and community; a sense of foreboding, isolation, and lack of social support; and disruption of life plans and rituals such as birthdays, weddings, religious holidays, recreational activities, and funerals.

abstract:
  The worldwide corona virus (COVID‐19) has had profound effects on all aspects of life: physical health, the ability to travel locally or to more distant destinations, material and financial resources, and psychosocial wellbeing. Couples, families, and communities and individual persons in those relationships have struggled to cope with emerging depression, anxiety, and trauma, and the rise of relational conflict. In this article, we suggest that the existential nature of the pandemic’s challenges require more than just the usual psychosocial interventions. We propose a taxonomy of responses to foster coping and resilience – “Reaching Up, Down, In, and Around”. “Reaching Up” includes accessing spiritual, religious, and ethical values. “Reaching Down” includes ideas and practices that foster a revised relationship with the Earth and its resources, and that engage families to participate in activities that aid the Earth’s recovery from decades of human‐caused damage. “Reaching In” represents a turn towards experiences available in the mind and in shared minds in relationships that provide pleasure, excitement, joy, and peace, given that external sources of these emotions are of limited availability due to quarantine. “Reaching Around” involves reframing the mandate for “social distancing” as fostering social connection and support while maintaining physical distancing. The challenges for family therapists, whose practices are confined largely to online therapy, and who are struggling with the same fears and constraints as those persons they are attempting to help, are also discussed.


id: cord-271867-n563yqw4
author: Falicov, Celia
date: 2020-07-14
txt: ./txt/cord-271867-n563yqw4.txt
cache: ./cache/cord-271867-n563yqw4.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.1111/famp.12578
doi: 10.1111/famp.12578
summary:
  We compare and contrast the learnings of flexibility of time, space, procedures or attendance we acquired in this clinical community setting during regular times, with the new challenges families and therapists face, and the adaptations needed to continue to work with our clients in culturally responsive and empowering ways during the Covid‐19 pandemic. During Covid-19, the SRFC physicians, pharmacy team, medical students, staff, volunteers, mental health team, social workers, and promotoras (experienced community members who are core staff and act as "trust bridges" to the community (Beck, 2005) ) have come together to continue to provide health, mental health care and emotional support through telemedicine and delivery of medications and food to patients'' homes. Relying on our learnings about providing services to under resourced families and communities in regular times, during the Covid-19 pandemic we expand the limits of what appears possible in a variety of new ways.

title:
  Expanding Possibilities: Flexibility and Solidarity with Under Resourced Immigrant Families During the Covid‐19 Pandemic

abstract:
  The novel coronavirus has added new anxieties and forms of grieving to the myriad practical and emotional burdens already present in the lives of underserved and uninsured immigrant families and communities. In this article, we relate our experiences since the Covid‐19 crisis to the lessons we have learned over time as mental health professionals working with families in no‐cost, student‐managed community comprehensive health clinics in academic‐community partnerships. We compare and contrast the learnings of flexibility of time, space, procedures or attendance we acquired in this clinical community setting during regular times, with the new challenges families and therapists face, and the adaptations needed to continue to work with our clients in culturally responsive and empowering ways during the Covid‐19 pandemic. We describe families, students, professionals, promotoras (community links) and IT support staff joining together in solidarity as the creative problem solvers of new possibilities when families do not have access to Wifi, smart phones or computers, or suffer overcrowding and lack of privacy. We describe many anxieties related to economic insecurity or fear of facing death alone, but also how to visualize expanding possibilities in styles of parenting or types of emotional support among family members as elements of hope that may endure beyond these unprecedented tragic times of loss and uncertainty.


id: cord-272772-zqmychmr
author: Stall, Nathan M.
date: 2020-08-03
txt: ./txt/cord-272772-zqmychmr.txt
cache: ./cache/cord-272772-zqmychmr.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.1016/j.jamda.2020.07.038
doi: 10.1016/j.jamda.2020.07.038
summary:
  Canada, and regions across the country begin phased re-openings, experts and advocates have 24 grown increasingly concerned that subsequent visiting policies and family caregiver access to 25 nursing home settings remain overly restrictive, causing substantial and potentially irreversible 26 harm to the health and wellbeing of residents. 4 A more balanced approach is needed that both 27 prevents the introduction of COVID-19 into nursing homes, but also allows family caregivers 28 and visitors to provide much needed contact, support and care to residents, to maintain their 29 overall health and wellbeing. These recommendations 68 focus on family caregivers and general visitors rather than essential support workers and nursing 69 home staff, and are made with the acknowledgement that the approach to visiting may need to be 70 dynamic based on the community prevalence of COVID-19.

title:
  Finding the Right Balance: An Evidence-Informed Guidance Document to Support the Re-Opening of Canadian Nursing Homes to Family Caregivers and Visitors during the COVID-19 Pandemic

abstract:
  Abstract During the first few months of the COVID-19 pandemic, Canadian nursing homes implemented strict no-visitor policies to reduce the risk of introducing COVID-19 in these settings. There are now growing concerns that the risks associated with restricted access to family caregivers and visitors have started to outweigh the potential benefits associated with preventing COVID-19 infections. Many residents have sustained severe and potentially irreversible physical, functional, cognitive, and mental health declines. As Canada emerges from its first wave of the pandemic, nursing homes across the country have cautiously started to reopen these settings, yet there is broad criticism that emerging visitor policies are overly restrictive, inequitable and potentially harmful. We reviewed the nursing home visitor policies for Canada’s ten provinces and three territories as well as international policies and reports on the topic to develop evidence-informed, data-driven and expert-reviewed guidance for the re-opening of Canadian nursing homes to family caregivers and visitors.


id: cord-272901-dsnbh4t1
title: Ten Years of Marriage and Cohabitation Research in the Journal of Family and Economic Issues
author: Dew, Jeffrey
date: 2020-10-22
txt: ./txt/cord-272901-dsnbh4t1.txt
cache: ./cache/cord-272901-dsnbh4t1.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.1007/s10834-020-09723-7
doi: 10.1007/s10834-020-09723-7
summary:
  Thus, although no one aspect, theme, or methodology links the 36 studies I reviewed, many of them examined issues related to family structure and/or economic changes that have occurred over the past sixty years in the US and other nations. For the purposes of this review, I categorized a study as examining an underrepresented group if the sample was largely composed of individuals from race/ethnic minority groups, interracial couples, sexual minorities, low-income families, or from countries outside the United States. Many of the studies of the association between financial issues and relationship quality over the past three years have focused on the family stress model of economic pressure and marital distress (Conger et al. 1990 ), or simply "family stress model." Since its inception in 1990, many scholars have used this model to research the association between negative financial events, feelings of economic pressure, and marital quality.

abstract:
  I reviewed the 36 marriage and cohabitation studies from the Journal of Family and Economic Issues articles published between 2010–2019. Nearly all of the studies used quantitative methods, and two-thirds of them used publicly available nationally-representative data. The studies fell into roughly five, unevenly sized groups: family structure, relationship quality, division of labor/employment, money management, and an “other” category. Suggestions for future research include applying some of the important questions within the articles to underrepresented groups, further examining the process of how finances and relationship quality interrelate and doing more applied and translational research.


id: cord-272923-5ekgb0zx
author: Hjálmsdóttir, Andrea
date: 2020-09-19
txt: ./txt/cord-272923-5ekgb0zx.txt
cache: ./cache/cord-272923-5ekgb0zx.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.1111/gwao.12552
doi: 10.1111/gwao.12552
summary:
  In Iceland, as elsewhere, women work part-time jobs in higher numbers, and mothers reduce their labor participation following childbirth more often than do fathers (Gíslason & Símonardóttir, 2018) . In the following example, a mother of a 2-year-old working in mass media, who worked entirely from home as did her husband, described one of her days like this: "I''m a little anxious because of all this, the situation in society. This is in accordance with previous studies on gendered control of time among parents (Bryson, 2016; Friedman, 2015) and new research conducted during Covid-19 that indicate that unpaid work performed by mothers has increased during the pandemic (Craig & Churchill, 2020; Manzo & Minello, 2020) . One of the patterns identified in the reflections of the women in our study was how they seemed to be stunned by how uneven the division of labor turned out to be during the pandemic and how much time and energy they devoted to household chores and the management of the household, carrying out the mental work within the family.

title:
  “I have turned into a foreman here at home.” Families and work‐life balance in times of Covid‐19 in a gender equality paradise.

abstract:
  This article explores the gendered realities of work‐life balance in Iceland during the Covid‐19 pandemic, in particular how these societal changes reflect and affect the gendered division of unpaid labor, such as childcare and household chores. The study draws on open ended real‐time diary entries, collected for two weeks during the peak of the pandemic in Iceland. The entries represent the voices of 37 mothers in heteronormative relationships. The findings imply that, during the pandemic, the mothers took on greater mental work than before. They also described intense emotional labor, as they tried to keep everyone calm and safe. The division of tasks at home lay on their shoulders, causing them stress and frustration. The findings suggest that, even in a country that has been at the top of the Gender Gap Index for several years, an unprecedented situation like Covid‐19 can reveal and exaggerate strong gender norms and expectations towards mothers. This article is protected by copyright. All rights reserved.


id: cord-273140-etod8fgd
author: Ritchey, Katherine C.
date: 2020-08-07
txt: ./txt/cord-273140-etod8fgd.txt
cache: ./cache/cord-273140-etod8fgd.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pubmed/32762477/
doi: 10.1177/1049909120948235
summary:
  Products from this project included a standard operating procedure for safe use of tablet computers for inpatient palliative care consultations and family visitations; tablet procurement with installation of video telehealth software; and training and education for clinical staff and other stakeholders. The COVID-19 pandemic posed a threat to essential palliative care services, including building connections between patients, families, and healthcare teams; mitigating isolation, loneliness, and fear; managing symptoms; determining care priorities in the face of life threatening illness; and promoting comfort, connectedness and dignity during the dying process. This included procuring tablets that operated through guest wi-fi services and completing "test calls" confirming our ability to perform telehealth encounters throughout the facility; training PCT members in the use of VA and non-VA video conferencing platforms; and developing a facility-wide standard operating procedure (SOP) for the safe use of tablet computers for clinical video telehealth consultations and patient-family visitations for both inpatient Palliative Care Services and CLC Veterans (Supplemental Table 1 ).

title:
  Reinventing Palliative Care Delivery in the Era of COVID-19: How Telemedicine Can Support End of Life Care

abstract:
  Telemedicine technology has become essential to healthcare delivery in the COVID-19 era, but concerns remain regarding whether the intimacy and communication that is central to high-quality palliative care will be compromised by the use of this technology. We employed a business model approach to identify the need for system innovation in palliative care, and a quality improvement approach to structure the project. Products from this project included a standard operating procedure for safe use of tablet computers for inpatient palliative care consultations and family visitations; tablet procurement with installation of video telehealth software; and training and education for clinical staff and other stakeholders. We describe a case illustrating the successful use of palliative care telehealth in the care of a COVID-19-positive patient at the end of life. Successful use of video telehealth for palliative care involved overcoming inertia to the development of telehealth infrastructure and learning clinical video telehealth skills; and engaging front-line care staff and family members who were open to a trial of telehealth for communication. Information gleaned from family about the patient as a person helped bedside staff to tailor care toward aspects meaningful to the patient and family and informed best practices to incorporate intimacy into future palliative video consultations and family visit.


id: cord-276741-ptrehipn
title: The downstream effects of COVID-19: a call for supporting family wellbeing in the NICU
author: Erdei, Carmina
date: 2020-07-24
txt: ./txt/cord-276741-ptrehipn.txt
cache: ./cache/cord-276741-ptrehipn.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.1038/s41372-020-0745-7
doi: 10.1038/s41372-020-0745-7
summary:
  In this paper, we propose utilizing the stress contagion framework and consider how psychosocial stress can "spill over" into the parent-infant relationship domain, which can impact child development and family wellbeing longer term. Although newborns may be less impacted by COVID-19 directly, there is concern that the pandemic and the necessary public health measures employed in response may negatively impact the psychosocial health of high-risk infants and their families in the Neonatal Intensive Care Unit (NICU). As the neonatal community has expeditiously employed novel strategies to meet the medical needs of infants affected by COVID-19, it is important to also consider the psychological short-and long-term effects of the pandemic on NICU families. As stress contagion in the NICU can negatively impact parent-infant relationships, strategies are needed to mitigate it in order to optimize child development and family resilience during this unparalleled period.

abstract:
  Parents of NICU infants are a vulnerable population from a psychological perspective, and often experience high levels of acute stress, depression, anxiety, and post-traumatic stress. The added burden of the current SARS CoV-2 disease (COVID-19) pandemic is likely to exacerbate these issues, with potential implications for the wellbeing of infants and families in the short- and long-term. In this paper, we propose utilizing the stress contagion framework and consider how psychosocial stress can “spill over” into the parent-infant relationship domain, which can impact child development and family wellbeing longer term. As the effects of the pandemic will likely persist well beyond the acute stage, we offer advocacy points and general guidelines for healthcare professionals to consider in their quest to mitigate stress and build resilience in NICU families.


id: cord-280619-xcre2zgh
title: Identifying Public Health Competencies Relevant to Family Medicine
author: Harvey, Bart J.
date: 2011-09-28
txt: ./txt/cord-280619-xcre2zgh.txt
cache: ./cache/cord-280619-xcre2zgh.txt
extension: .txt
mime: text/plain
url: https://www.sciencedirect.com/science/article/pii/S0749379711003576
doi: 10.1016/j.amepre.2011.06.002
summary:
  Using a multi-staged, iterative process that included a detailed literature review, the authors developed a set of public health competencies relevant to primary care, identifying competencies relevant across four levels, from "post-MD" to "enhanced." Feedback from family medicine and public health educator–practitioners regarding the set of proposed "essential" competencies indicated the need for a more limited, feasible set of "priority" areas to be highlighted during residency training. This focused set of public health competencies has begun to guide relevant components of the University of Toronto''s Family Medicine Residency Program curriculum, including academic half-days; clinical experiences, especially identifying "teachable moments" during patient encounters; resident academic projects; and elective public health agency placements. This revised draft was then sent to all symposium participants for additional review and feedback, which resulted in the proposal of a detailed set of public health competencies relevant to family medicine and primary care (Appendix B, available online at www.ajpmonline.org).

abstract:
  Public health situations faced by family physicians and other primary care practitioners, such as severe acute respiratory syndrome (SARS) and more recently H1N1, have resulted in an increased interest to identify the public health competencies relevant to family medicine. At present there is no agreed-on set of public health competencies delineating the knowledge and skills that family physicians should possess to effectively face diverse public health challenges. Using a multi-staged, iterative process that included a detailed literature review, the authors developed a set of public health competencies relevant to primary care, identifying competencies relevant across four levels, from “post-MD” to “enhanced.” Feedback from family medicine and public health educator–practitioners regarding the set of proposed “essential” competencies indicated the need for a more limited, feasible set of “priority” areas to be highlighted during residency training. This focused set of public health competencies has begun to guide relevant components of the University of Toronto's Family Medicine Residency Program curriculum, including academic half-days; clinical experiences, especially identifying “teachable moments” during patient encounters; resident academic projects; and elective public health agency placements. These competencies will also be used to guide the development of a family medicine–public health primer and faculty development sessions to support family medicine faculty facilitating residents to achieve these competencies. Once more fully implemented, an evaluation will be initiated to determine the degree to which these public health competencies are being achieved by family medicine graduates, especially whether they attained the knowledge, skills, and confidence necessary to effectively face diverse public health situations—from common to emergent.


id: cord-288673-ku3tmjd3
title: Microbial and fungal protease inhibitors—current and potential applications
author: Sabotič, Jerica
date: 2012-01-05
txt: ./txt/cord-288673-ku3tmjd3.txt
cache: ./cache/cord-288673-ku3tmjd3.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.1007/s00253-011-3834-x
doi: 10.1007/s00253-011-3834-x
summary:
  Because proteases play essential roles in life and death processes in all living organisms and because peptide bond hydrolysis is irreversible, anomalies in proteolytic activities lead to numerous pathological conditions, including cancer, neurodegenerative disorders and inflammatory and cardiovascular diseases, as well as bacterial, viral and parasitic diseases (Lopez-Otin and Bond 2008; Turk 2006) . Another important oral cavity pathogen involved in periodontal disease, Porphyromonas gingivalis, in addition to a few cysteine proteases (discussed further in the following), produces a serine protease, a prolyl tripeptidyl peptidase PtpA (family S9), which is involved in degrading host connective tissue, providing nutrients for bacterial growth (Banbula et al. Several proteases of the serine catalytic type have also been targeted for the design of specific protease inhibitors for use in cancer treatment, including the urokinase plasminogen activator and matriptase (Abbenante and Fairlie 2005; Bialas and Kafarski 2009; Ulisse et al.

abstract:
  Proteolytic enzymes play essential metabolic and regulatory functions in many biological processes and also offer a wide range of biotechnological applications. Because of their essential roles, their proteolytic activity needs to be tightly regulated. Therefore, small molecules and proteins that inhibit proteases can be versatile tools in the fields of medicine, agriculture and biotechnology. In medicine, protease inhibitors can be used as diagnostic or therapeutic agents for viral, bacterial, fungal and parasitic diseases as well as for treating cancer and immunological, neurodegenerative and cardiovascular diseases. They can be involved in crop protection against plant pathogens and herbivorous pests as well as against abiotic stress such as drought. Furthermore, protease inhibitors are indispensable in protein purification procedures to prevent undesired proteolysis during heterologous expression or protein extraction. They are also valuable tools for simple and effective purification of proteases, using affinity chromatography. Because there are such a large number and diversity of proteases in prokaryotes, yeasts, filamentous fungi and mushrooms, we can expect them to be a rich source of protease inhibitors as well.


id: cord-291361-2vn1o7ag
author: Li, Jing
date: 2020-07-06
txt: ./txt/cord-291361-2vn1o7ag.txt
cache: ./cache/cord-291361-2vn1o7ag.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.1017/s0950268820001491
doi: 10.1017/s0950268820001491
summary:
  title: Epidemiological and clinical characteristics of three family clusters of COVID-19 transmitted by latent patients in China The epidemiological and clinical characteristics of the family cluster patients were analysed and compared with those of 43 contemporaneous sporadic cases. In terms of epidemiological characters and clinical symptoms, no significant differences were observed between the family cluster and sporadic cases. In this study, we aimed to investigate the epidemiological and clinical characteristics of these three family clusters of COVID-19 cases by comparing them with sporadic cases, which would provide insights for epidemic control in the context of the current serious situation worldwide. This study revealed that sporadic cases had lower levels of albumin and lymphocyte counts than family cluster cases; otherwise, there were no significant differences in terms of other epidemiological characters and clinical features between the two groups. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China

title:
  Epidemiological and clinical characteristics of three family clusters of COVID-19 transmitted by latent patients in China

abstract:
  From 21 January 2020 to 9 February 2020, three family clusters involving 31 patients with coronavirus disease 2019 were identified in Wenzhou, China. The epidemiological and clinical characteristics of the family cluster patients were analysed and compared with those of 43 contemporaneous sporadic cases. The three index cases transmitted the infection to 28 family members 2–10 days before illness onset. Overall, 28 of the 41 sporadic cases and three of 31 patients in the family clusters came back from Wuhan (65.12 vs. 9.68%, P< 0.001). In terms of epidemiological characters and clinical symptoms, no significant differences were observed between the family cluster and sporadic cases. However, the lymphocyte counts of sporadic cases were significantly lower than those of family cluster cases ((1.32 ± 0.55) × 10(9)/l vs. (1.63 ± 0.70) × 10(9)/l, P = 0.037), and the proportion of hypoalbuminaemia was higher in sporadic cases (18/43, 41.86%) than in the family clusters (6/31, 19.35%) (P < 0.05). Within the family cluster, the second- and third-generation cases had milder clinical manifestations, without severe conditions, compared with the index and first-generation cases, indicating that the virulence gradually decreased following passage through generations within the family clusters. Close surveillance, timely recognition and isolation of the suspected or latent patient is crucial in preventing family cluster infection.


id: cord-291950-9gtsqyfj
title: Introduction: The Clans and Families of Cysteine Peptidases
author: Rawlings, Neil D.
date: 2012-11-09
txt: ./txt/cord-291950-9gtsqyfj.txt
cache: ./cache/cord-291950-9gtsqyfj.txt
extension: .txt
mime: text/plain
url: https://api.elsevier.com/content/article/pii/B978012382219200404X
doi: 10.1016/b978-0-12-382219-2.00404-x
summary:
  A non-peptidase homolog is known from Trypanosoma brucei in which the catalytic Cys has been replaced by Ser. Family C10 contains streptopain (Chapter 483) and a few similar enzymes, all of which are from gram-positive bacteria. An alignment shows that residues Gln31, Cys32, His95 and Asn113 are conserved, suggesting that the N-terminal domain is a cysteine peptidase with a papain-like fold, which we include in family C51. The ''papain-like'' endopeptidases of RNA viruses form a large group of cysteine peptidases that contain the catalytic dyad residues in the order Cys, His. All of the families had been included in clan CA, even though for many no tertiary structure for any member had been solved. Although no catalytic residues have been identified for any member of the family, they are predicted to occur in the order His, Glu, Gln, Cys. Family C57 contains the I7 protein from the vaccinia virus (Chapter 535), which is believed to be a polyprotein processing endopeptidase.

abstract:
  The third edition of the Handbook of Proteolytic Enzymes aims to be a comprehensive reference work for the enzymes that cleave proteins and peptides, and contains over 800 chapters. Each chapter is organized into sections describing the name and history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing features for a specific peptidase. The subject of Chapter 404 is Clans and Families of Cysteine Peptidases.


id: cord-293822-axr9qu58
title: COVID‐19 Pandemic: Applying a Multi‐Systemic Lens
author: Rolland, John S.
date: 2020-07-17
txt: ./txt/cord-293822-axr9qu58.txt
cache: ./cache/cord-293822-axr9qu58.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pubmed/32677711/
doi: 10.1111/famp.12584
summary:
  Highlighting the pattern of psychosocial issues of COVID‐19 over time, discussion emphasizes the evolving interplay of larger systems public health pandemic challenges and mitigation strategies with individual and family processes. The paper addresses issues of coping with myriad Covid‐19 uncertainties in the initial crisis wave and evolving phases of the pandemic in the context of individual and family development, pre‐existing illness or disability, and racial and socioeconomic disparities. In addition to communication processes and organizational/structural patterns, particular emphasis includes: family and individual life course development in relation to the time phases of a disorder; multigenerational legacies related to illness and loss; and belief systems (including influences of culture, ethnicity, race, spirituality, and gender) (Figure 1 ). As the pandemic continues to evolve, these discussions will need to be revisited -relating to new COVID-19 data and to changing family circumstances, such as life cycle transitions or altered economic and health status.

abstract:
  The COVID‐19 pandemic has a pervasive effect on all aspects of family life. We can distinguish the collective societal and community effects of the global pandemic and the risk and disease impact for individuals and families. This paper draws on Rolland’s Family Systems Illness (FSI) model to describe some of the unique challenges through a multi‐systemic lens. Highlighting the pattern of psychosocial issues of COVID‐19 over time, discussion emphasizes the evolving interplay of larger systems public health pandemic challenges and mitigation strategies with individual and family processes. The paper addresses issues of coping with myriad Covid‐19 uncertainties in the initial crisis wave and evolving phases of the pandemic in the context of individual and family development, pre‐existing illness or disability, and racial and socioeconomic disparities. The discussion offers recommendations for timely family oriented consultation and psychoeducation, and for healthcare clinician self‐care.


id: cord-302421-tvy7uo7u
title: Family Science in the Context of the COVID‐19 Pandemic: Solutions and New Directions
author: Brock, Rebecca L.
date: 2020-07-14
txt: ./txt/cord-302421-tvy7uo7u.txt
cache: ./cache/cord-302421-tvy7uo7u.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.1111/famp.12582
doi: 10.1111/famp.12582
summary:
  The primary aims of this article were to (a) present a range of potential solutions to problems threatening the rigor of ongoing research and (b) propose new directions in family science aimed at understanding how families adapt to change and adversity arising from the pandemic. An example with particular relevance to family science is the Two-Method Missing Design, an approach used when there is a gold standard measure of a construct (e.g., behavioral observations of family interactions) that cannot be administered to all participants due to time, money, resources, or, in the case of COVID-19, social distancing guidelines. Drawing on past research and theory, we can investigate the specific impact of the stress and adversity arising from COVID-19 on individual mental health and family functioning and identify modifiable risk and resiliency factors to target in interventions. In the absence of ongoing longitudinal studies, the COVID-19 pandemic presents another avenue for family scientists to pursue new research on the impact of stress and adversity on family functioning.

abstract:
  The coronavirus disease 2019 (COVID‐19) pandemic has precipitated substantial global disruption and will continue to pose major challenges. In recognition of the challenges currently faced by family scientists, we share our perspectives about conducting family research in the context of the COVID‐19 pandemic. There are two primary issues we address in this article. First, we present a range of potential solutions to challenges in research, resulting from the pandemic, and discuss strategies for preserving ongoing research efforts. We discuss approaches to scaling back existing protocols, share ideas for adapting lab‐based measures for online administration (e.g., using video chat platforms), and suggest strategies for addressing missing data and reduced sample size due to lower participation rates and funding restrictions. We also discuss the importance of measuring COVID‐19 relevant factors to use as controls or explore as moderators of primary hypotheses. Second, we discuss how the COVID‐19 pandemic represents a scientifically important context for understanding how families adjust and adapt to change and adversity. Increased stress precipitated by the pandemic, varying from acute stress associated with job loss to more chronic and enduring stress, will undoubtedly take a toll. We discuss ways that family scientists can contribute to pandemic‐related research to promote optimal family functioning and protect the health of family members.


id: cord-308014-130k8v21
title: Family Caregiving for Acute-Critically Ill Older Adults in the Time of COVID-19
author: Happ, Mary Beth
date: 2020-10-21
txt: ./txt/cord-308014-130k8v21.txt
cache: ./cache/cord-308014-130k8v21.txt
extension: .txt
mime: text/plain
url: https://www.sciencedirect.com/science/article/pii/S0197457220303086?v=s5
doi: 10.1016/j.gerinurse.2020.10.008
abstract: nan
summary:
  title: Family Caregiving for Acute-Critically Ill Older Adults in the Time of COVID-19 It is fitting that in this last year, we observed Geriatric Nursing''s 40 th anniversary with several columns that involved "taking stock" of acute-critical care for older people as well as review of progress on ageism, physical restraint use, and accommodations for patient communication impairment in acute-critical care. Vulnerable older patients enter acute-critical care settings without the supportive presence and advocacy of family caregivers. Gerontological nurses are uniquely qualified to support family caregivers as they interact with acute-critical care in remote and creative ways during the COVID-19 pandemic. Family Caregiving for Older Adults admitted to Acute -Critical Care COVID-related family separation during acute-critical illness impacts older adult patients, family caregivers, and nurses on multiple levels and is likely to have long-term traumatic effects. [8] Health policy and programmatic initiatives are desperately needed to provide tangible support for family caregivers of frail older adults.


id: cord-308267-c4wu92tt
title: The “Flip”—Sustaining Complexity and Multiplicity Post‐Quarantine
author: Dickerson, Victoria C.
date: 2020-07-14
txt: ./txt/cord-308267-c4wu92tt.txt
cache: ./cache/cord-308267-c4wu92tt.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.1111/famp.12583
doi: 10.1111/famp.12583
summary:
  Linking‐Lives Storython, created specifically to utilize our Covid shelter‐in‐place experience; Re‐Authoring Teaching: Creating a Collaboratory, begun 12 years ago to meet the needs of a wide‐spread community; and Witness‐to‐Witness, a current response to contemporary disastrous situations—all have utilized technology to open possibilities for those who are helped as well as those who are helpers. We began to recognize what had been unremarkable to us previously: what it means to interact as clinician and client in a therapy room, in a physical space designed specifically for the sharing of experience, for personal communication and understanding. Is there a way to think about our current dilemma of pandemic/quarantine, our need to rely on technology in our systems work, that could help us see a way forward from a "positive deviance" understanding?

abstract:
  This article describes poststructural ways of responding to the pandemic by looking for openings or gaps within more traditional ways of interacting with dilemmas. The author situates herself within a “positive deviance “ epistemology, which looks for what already works rather than getting captured by the current problem. We “flip” what are the usual ways of responding and explore three different programs that illustrate inventive and assets‐based approaches. Linking‐Lives Storython, created specifically to utilize our Covid shelter‐in‐place experience; Re‐Authoring Teaching: Creating a Collaboratory, begun 12 years ago to meet the needs of a wide‐spread community; and Witness‐to‐Witness, a current response to contemporary disastrous situations—all have utilized technology to open possibilities for those who are helped as well as those who are helpers. The article shows how each program has specifically flipped more traditional ways of responding, but also how this “flip” employs a practice of “disciplined improvisation.” Each program has a built‐in structure that depends on technology to make it work; each has a disciplined approach that allows the helpers to improvise to meet the needs of the receivers. It is this “flip,” this way of thinking, that can sustain us and our work in times of great complexity and multiplicity.


id: cord-313887-8sabsrgy
author: Quandt, Sara A.
date: 2020-08-10
txt: ./txt/cord-313887-8sabsrgy.txt
cache: ./cache/cord-313887-8sabsrgy.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pubmed/32785108/
doi: 10.3390/ijerph17165786
summary:
  Taken together, the rapidly changing messages, coupled with public concern, and limited availability of up-to-date information in formats for those with limited English proficiency created a situation in the USA in which Latinx workers such as farmworkers were likely to lack consistent and accurate information and, as a result, practice ineffective behaviors to protect themselves and prevent spreading disease to their social network. This study was designed to describe the knowledge, perceived risk and susceptibility, and preventive behaviors reported by Latinx immigrant farmworker and nonfarmworker families in North Carolina during the first months of the COVID-19 pandemic. In total, these results indicate that, despite relatively high knowledge, strong perceptions of risk from COVID-19, and claims of avoiding situations where contracting or spreading infection might be likely, many of the farmworker families included here do not practice safe physical distancing measures as recommended; and their use of masks appears to be confined to work settings.

title:
  COVID-19 Pandemic among Latinx Farmworker and Nonfarmworker Families in North Carolina: Knowledge, Risk Perceptions, and Preventive Behaviors

abstract:
  (1) Background: The COVID-19 pandemic poses substantial threats to Latinx farmworkers and other immigrants in food production and processing. Classified as essential, such workers cannot shelter at home. Therefore, knowledge and preventive behaviors are important to reduce COVID-19 spread in the community. (2) Methods: Respondents for 67 families with at least one farmworker (FWF) and 38 comparable families with no farmworkers (nonFWF) in North Carolina completed a telephone survey in May 2020. The survey queried knowledge of COVID-19, perceptions of its severity, self-efficacy, and preventive behaviors. Detailed data were collected to document household members’ social interaction and use of face coverings. (3) Results: Knowledge of COVID-19 and prevention methods was high in both groups, as was its perceived severity. NonFWF had higher self-efficacy for preventing infection. Both groups claimed to practice preventive behaviors, though FWF emphasized social avoidance and nonFWF emphasized personal hygiene. Detailed social interactions showed high rates of inter-personal contact at home, at work, and in the community with more mask use in nonFWF than FWF. (4) Conclusions: Despite high levels of knowledge and perceived severity for COVID-19, these immigrant families were engaged in frequent interpersonal contact that could expose community members and themselves to COVID-19.


id: cord-322679-jrsg8pdk
author: Hu, Na
date: 2020-10-09
txt: ./txt/cord-322679-jrsg8pdk.txt
cache: ./cache/cord-322679-jrsg8pdk.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.3389/fpsyg.2020.576515
doi: 10.3389/fpsyg.2020.576515
summary:
  Our study also indicates that improvements in the family environment benefit the mental health care of the medical staff, and high self-efficacy enhances this effect. Mediating effect analysis was performed to explore the role of self-efficacy in the relationship between family environment and symptoms of anxiety and depression. The results showed that there were statistically significant relationships between the anxiety and depressive symptoms of medical staff, their family environment, and their sense of self-efficacy. The medical staff members with low cohesion and expressiveness, as well as high conflict in the family environment, were more likely to show anxiety and depressive symptoms during the epidemic. In the current study, we found that the anxiety and depressive symptoms of medical staff during the COVID-19 outbreak was closely related to their family environment, and their self-efficacy regulated the relationship between them.

title:
  Impact of the Family Environment on the Emotional State of Medical Staff During the COVID-19 Outbreak: The Mediating Effect of Self-Efficacy

abstract:
  During the outbreak of the coronavirus disease 2019 (COVID-19), the medical staff was facing severe work pressure, which led to a negative emotional state. The purpose of this study was to explore the relationship between the family environment and the emotional state of the medical staff members during the COVID-19 outbreak. Due to the importance of self-efficacy in regulating mental health, the mediating role of self-efficacy in the association between family environment and emotional state was also explored. A cross-sectional survey was performed, using an online questionnaire, on 645 medical staff who participated in the epidemic prevention and control tasks during the COVID-19 outbreak in Beijing. Family environment, self-efficacy, anxiety, and depressive symptoms were measured by the Family Environment Scale-Chinese Version (FES-CV), the General Self-Efficacy Scale (GSES), the Generalized Anxiety Disorder Scale-7 (GAD-7), and the Patient Health Questionnaire-9 (PHQ-9), respectively. Correlation analysis and mediating effect analysis were used to explore the relationships between them. First, a higher prevalence of anxiety (39%) and depressive (33%) symptoms were confirmed among the medical staff. Second, the symptoms of anxiety and depression were negatively correlated with the dimensions of cohesion and expressiveness and positively correlated with the dimensions of conflict in the FES-CV scale. Third, self-efficacy significantly mediated the association between the family environment and anxiety symptoms (P < 0.001) as well as the family environment and depressive symptoms (P < 0.001). These findings show that a negative family environment was the main predictor of symptoms of anxiety and depression in the medical staff during the COVID-19 outbreak. Furthermore, we found that self-efficacy played a critical mediating role between the family environment and the symptoms of anxiety and depression. Our study also indicates that improvements in the family environment benefit the mental health care of the medical staff, and high self-efficacy enhances this effect.


id: cord-322907-e0pmyvdq
title: On the fly: Adapting quickly to emergency remote instruction in a family literacy programme
author: Kaiper-Marquez, Anna
date: 2020-10-14
txt: ./txt/cord-322907-e0pmyvdq.txt
cache: ./cache/cord-322907-e0pmyvdq.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.1007/s11159-020-09861-y
doi: 10.1007/s11159-020-09861-y
summary:
  Even Start integrated "early childhood education, adult literacy (adult basic and secondary-level education and instruction for English language learners), parenting education, and interactive parent and child literacy activities for low-This article examines how instructors at the Goodling Institute for Research in Family Literacy (GI) at The Pennsylvania State University have responded to the pandemic by converting face-to-face family literacy classes into online, remote instruction. We argue that although the pandemic has presented unprecedented challenges for adult educators and learners in the United States (US) and around the world, it has also compelled instructors to use remote instruction creatively and has revealed the critical importance of family literacy programmes as an educational support system for families. In one of the only studies examining DE in family literacy, Beschorner and Hutchison (2016) compared the experiences and outcomes of adult learners completing a parent education class through face-to-face classes with those who had received online instruction.

abstract:
  The COVID-19 pandemic has led to extraordinary changes in family literacy instruction, forcing face-to-face programmes to shift rapidly (or “on the fly”) to online, remote instruction. This study is one of the few on online teaching and learning in family literacy and, to the knowledge of the authors, the first on emergency remote instruction in a family literacy programme during the COVID-19 pandemic. This article examines how the Goodling Institute for Research in Family Literacy at The Pennsylvania State University in the United States has responded to the pandemic by converting its face-to-face family literacy classes into emergency remote instruction using online platforms. Serving eight immigrant families in 2019–2020 who live in the State College area in central Pennsylvania, the Family Pathways programme includes adult education, parent education and interactive parent–child literacy activities. The article discusses how teachers created online learning opportunities for parents and children to learn together, the strategies and resources instructors used to teach remotely, how challenges such as discomfort with technology were addressed, and what has been learned from the experience. Although COVID-19 presents unprecedented challenges for educators and learners in family literacy programmes more broadly, it has also compelled instructors in this particular programme to use remote instruction creatively and has revealed the critical importance of family literacy programmes as an educational support system for low-income and immigrant families.


id: cord-324857-ll3xmk3i
author: Jenkins, Louis S.
date: 2020-06-09
txt: ./txt/cord-324857-ll3xmk3i.txt
cache: ./cache/cord-324857-ll3xmk3i.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pubmed/32634002/
doi: 10.4102/phcfm.v12i1.2478
summary:
  Ten family physicians and family medicine registrars in a South African semi-rural training complex reflected on the coronavirus disease 2019 (COVID-19) crisis during their quarterly training complex meeting. Ten family physicians and family medicine registrars in a South African semi-rural training complex reflected on the coronavirus disease 2019 (COVID-19) crisis during their quarterly training complex meeting. The importance of preventative and promotive care in a community-oriented approach, being a capacity builder and leading the health team as a consultant have assumed new meanings. The importance of preventative and promotive care in a community-oriented approach, being a capacity builder and leading the health team as a consultant have assumed new meanings. The roles of the family physician in South Africa and the contribution to district health services have been well described. Figure 2 (left side) presents the ''traditional'' model of how a family physician might exercise his or her roles during the COVID-19 crisis.

title:
  The evolving role of family physicians during the coronavirus disease 2019 crisis: An appreciative reflection

abstract:
  Ten family physicians and family medicine registrars in a South African semi-rural training complex reflected on the coronavirus disease 2019 (COVID-19) crisis during their quarterly training complex meeting. The crisis has become the disruptor that is placing pressure on the traditional roles of the family physician. The importance of preventative and promotive care in a community-oriented approach, being a capacity builder and leading the health team as a consultant have assumed new meanings.


id: cord-333663-0yzrcfe5
title: Family-Centered Care During the COVID-19 Era
author: Hart, Joanna L.
date: 2020-04-22
txt: ./txt/cord-333663-0yzrcfe5.txt
cache: ./cache/cord-333663-0yzrcfe5.txt
extension: .txt
mime: text/plain
url: https://www.sciencedirect.com/science/article/pii/S0885392420302086?v=s5
doi: 10.1016/j.jpainsymman.2020.04.017
summary:
  However, during the COVID-19 pandemic, maintaining public safety necessitates restricting the physical presence of families for hospitalized patients. We provide a toolbox of strategies for supporting family-centered inpatient care during physical distancing responsive to the current clinical climate. Strategies for delivering family-centered care typically include open family presence at the bedside; 3 regular, structured communication with family members; and multidisciplinary support. 3 Physical, or social, distancing is the principal mitigation strategy used to reduce transmission in the COVID-19 pandemic, 4 with a profound impact on the delivery of family-centered inpatient care. During the COVID-19 pandemic, family presence must be supported in non-physical ways to achieve the goals of family-centered care. Family-centered care strategies in this context must acknowledge the changed ethical perspective and clinicians'' limited time, attention, and effort to devote to learning and assimilation. Strategies to support family presence during physical distancing rely heavily on existing patient or family smartphones and computers, stable internet access, and technological literacy.

abstract:
  Family support is more, not less, important during crisis. However, during the COVID-19 pandemic, maintaining public safety necessitates restricting the physical presence of families for hospitalized patients. In response, health systems must rapidly adapt family-centric procedures and tools to circumvent restrictions on physical presence. Strategies for maintaining family integrity must acknowledge clinicians’ limited time and attention to devote to learning new skills. Internet-based solutions can facilitate the routine, predictable, and structured communication which is central to family-centered care. But the reliance on technology may compromise patient privacy and exacerbate racial, socioeconomic, and geographic disparities for populations that lack access to reliable internet access, devices or technological literacy. We provide a toolbox of strategies for supporting family-centered inpatient care during physical distancing responsive to the current clinical climate. Innovations in the implementation of family involvement during hospitalizations may lead to long-term progress in the delivery of family-centered care.


id: cord-335582-30rws724
title: The impact of lockdown on the learning gap: family and school divisions in times of crisis
author: Bonal, Xavier
date: 2020-09-15
txt: ./txt/cord-335582-30rws724.txt
cache: ./cache/cord-335582-30rws724.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pubmed/32952208/
doi: 10.1007/s11159-020-09860-z
summary:
  Middle-class families were able to maintain higher standards of education quality in a critical context, while children from socially disadvantaged families had few learning opportunities both in terms of time and learning experiences (schoolwork and maintenance of after-school activities). During the COVID-19 Catalan lockdown, the instructional time received by students from different social backgrounds has been unequal, as has the educational value of the activities developed at home in non-school time. Extant research evidence based on these experiences identifies the existence of a general loss of learning connected to school absence, which can be more or less severe depending on students'' previous performance, family characteristics, age, and education pathway, among other factors. Inequalities in families'' economic, social and cultural capital impacted on student learning opportunities by different means, including school responses to the lockdown, access to digital facilities and the level of parental learning support.

abstract:
  The lockdown of schools in Spain to confront the effects of COVID-19 caused an enormous impact at both societal and educational levels. Schools and families had to react rapidly to a new teaching and learning scenario without the benefit of previous planning or government guidelines. In this context, some schools were better able to adapt to the new circumstances than others. Likewise, the structure and size of families’ economic, social and cultural capital produced significant differences in the learning opportunities for children from different backgrounds. This article assesses the impact of the school lockdown on the learning gap between children from different social backgrounds in Catalonia. Based on 35,419 responses to an online survey administered between 26 and 30 March 2020 to families with children aged between 3 and 18, the authors’ analysis shows that learning opportunities varied significantly. Middle-class families were able to maintain higher standards of education quality in a critical context, while children from socially disadvantaged families had few learning opportunities both in terms of time and learning experiences (schoolwork and maintenance of after-school activities). Results differed by type of school (public/private) where students were enrolled, family economic, social and cultural capital, and family living conditions. In the final part of the article, the authors highlight the importance of the role of the school in ensuring learning opportunities for children from low socioeconomic backgrounds, and they discuss some policy implications of their findings.


id: cord-339795-1bo38ooy
title: Well-Being and Stability among Low-income Families: A 10-Year Review of Research
author: Sano, Yoshie
date: 2020-10-25
txt: ./txt/cord-339795-1bo38ooy.txt
cache: ./cache/cord-339795-1bo38ooy.txt
extension: .txt
mime: text/plain
url: https://www.ncbi.nlm.nih.gov/pubmed/33132672/
doi: 10.1007/s10834-020-09715-7
summary:
  In the last decade, research on the economic security of lowincome families has centered around poverty dynamics, the effectiveness of welfare-to-work programs, employment issues, the Earned Income Tax Credit, and banking behavior. (2015) developed the Economic Well-Being Continuum (EWC) as a comprehensive measure to describe the circumstances of low-income families in eight specific dimensions (child care, employability, food security, health care security, housing security, transportation, reliance of assistance programs, and capabilities) and establish their level of economic functioning (persistently poor, struggling, and getting by). Employment issues â�¢ Rural low-income mothers remained in the same job because they utilized their limited resources effectively and developed strategies to combine work and family life including using social support network and supportive supervisors as well as flextime (Son and Bauer 2010) â�¢ Low-income mothers were more likely to be employed, especially full-time, if they were provided state childcare subsidy tied to their employment (Davis et al.

abstract:
  Scholarship on families in poverty, in the last decade, documented various struggles and challenges faced by low-income families and expanded our understanding of their complicated life circumstances embedded within the contexts of community, culture, and policies. The research articles published in the Journal of Family and Economic Issues during this time, that highlighted poverty, focused primarily on three topic areas: economic security, family life issues, and food security. Overall, findings conclude that family well-being and stability cannot be promoted without the consideration of environmental factors. They depend on the interaction among individual (e.g., increased human capital), family (e.g., positive co-parental relationship), community (e.g., affordable childcare), and policy changes (e.g., realistic welfare-to-work programs). Collectively, the articles have provided a road map for future research directions.


id: cord-341265-esc55vwj
title: Microbial enzymes catalyzing keratin degradation: Classification, structure, function
author: Qiu, Jingwen
date: 2020-08-05
txt: ./txt/cord-341265-esc55vwj.txt
cache: ./cache/cord-341265-esc55vwj.txt
extension: .txt
mime: text/plain
url: https://doi.org/10.1016/j.biotechadv.2020.107607
doi: 10.1016/j.biotechadv.2020.107607
summary:
  For example, family M28 and M3 proteases secreted from the non-pathogenic fungus Onygena corvina have been reported to catalyze degradation of pig bristle keratin, and moreover to act synergistically with enzymes from the S8 family . The keratinolytic enzymes in the different families may play different roles in the keratin degrading process, due to differences in their active sites, the preferred substrate cleavage sites and recognition of amino acid length. The family S9 exo-keratinases may play a key role in attacking products from endo-protease hydrolyzed keratin protein (Lange et al., 2016; Mercer and Stewart, 2019) , but is not highly efficient in directly degrading keratin. To obtain amino acids from keratin-rich materials using keratinolytic enzymes, a preliminary degradation of disulfide bonds is necessary to loosen the keratin structure and make the amino acid chains available for keratinase attack (Gupta et al., 2013b; Peng et al., 2019) .

abstract:
  Keratin is an insoluble and protein-rich epidermal material found in e.g. feather, wool, hair. It is produced in substantial amounts as co-product from poultry processing plants and pig slaughterhouses. Keratin is packed by disulfide bonds and hydrogen bonds. Based on the secondary structure, keratin can be classified into α-keratin and β-keratin. Keratinases (EC 3.4.-.- peptide hydrolases) have major potential to degrade keratin for sustainable recycling of the protein and amino acids. Currently, the known keratinolytic enzymes belong to at least 14 different protease families: S1, S8, S9, S10, S16, M3, M4, M14, M16, M28, M32, M36, M38, M55 (MEROPS database). The various keratinolytic enzymes act via endo-attack (proteases in families S1, S8, S16, M4, M16, M36), exo-attack (proteases in families S9, S10, M14, M28, M38, M55) or by action only on oligopeptides (proteases in families M3, M32), respectively. Other enzymes, particularly disulfide reductases, also play a key role in keratin degradation as they catalyze the breakage of disulfide bonds for better keratinase catalysis. This review aims to contribute an overview of keratin biomass as an enzyme substrate and a systematic analysis of currently sequenced keratinolytic enzymes and their classification and reaction mechanisms. We also summarize and discuss keratinase assays, available keratinase structures and finally examine the available data on uses of keratinases in practical biorefinery protein upcycling applications.


id: cord-343910-jib877fo
title: Does autism protect against COVID quarantine effects?
author: Guidotti, M.
date: 2020-10-14
txt: ./txt/cord-343910-jib877fo.txt
cache: ./cache/cord-343910-jib877fo.txt
extension: .txt
mime: text/plain
url: http://medrxiv.org/cgi/content/short/2020.10.13.20212118v1?rss=1
doi: 10.1101/2020.10.13.20212118
summary:
  95 autistic children followed by the child and adolescent psychiatry department of Tours university hospital were assessed from the 18th of March to the 8th of May. The following clinical points were investigated: child anxiety, family anxiety, behavior problems, impact on sleep, impact on appetite, impact on school work, family tension, confinement intolerance, difficulties to follow a schedule, isolation behavior. Results: Despite minor changes in family anxiety and school work, no difference was highlighted between clinical scores collected at the beginning and at the end of this period. . https://doi.org/10.1101/2020.10.13.20212118 doi: medRxiv preprint Eight clinical items (child anxiety, behavior problems, impact on sleep, impact on appetite, family tension, confinement intolerance, difficulties to follow a schedule, isolation behavior) had an average score of less than 2 and two items (family anxiety and impact on school work) were greater than 2 at both T1 and T2 time points (Fig.1) .

abstract:
  Introduction: COVID-19 outbreak has imposed an eight-week confinement in France. During this period, children and their families were exposed to a full-time home life. The aim of this study was to assess the emotional experience and tolerance of children with autism spectrum disorder (ASD) in this particular context. Method: A clinical survey was proposed to parents and rated by professionals once a week during the quarantine period in France. 95 autistic children followed by the child and adolescent psychiatry department of Tours university hospital were assessed from the 18th of March to the 8th of May. The following clinical points were investigated: child anxiety, family anxiety, behavior problems, impact on sleep, impact on appetite, impact on school work, family tension, confinement intolerance, difficulties to follow a schedule, isolation behavior. Results: Despite minor changes in family anxiety and school work, no difference was highlighted between clinical scores collected at the beginning and at the end of this period. ASD children with or without intellectual disability had non-significant clinical changes during quarantine. This evolution was also independent of the accommodation type (house or apartment) and the parental status (relationship, separated or isolated). Conclusion: The sameness dimension in autism and parents adaptation may be involved in this clinical stability during COVID confinement. Moreover, specialized tools and support provided by professionals could have participated to these outcomes and must be regularly promoted in order to help families in this still difficult period.


id: cord-346062-q0trgj12
title: Ethical dilemmas due to the Covid-19 pandemic
author: Robert, René
date: 2020-06-17
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url: https://doi.org/10.1186/s13613-020-00702-7
doi: 10.1186/s13613-020-00702-7
summary:
  The devastating pandemic that has stricken the worldwide population induced an unprecedented influx of patients in ICUs, raising ethical concerns not only surrounding triage and withdrawal of life support decisions, but also regarding family visits and quality of end-of-life support. As a result, four new options never applied to date were considered with the common aim of saving a maximum number of lives: to prioritize ICU beds for patients with the best prognosis; to increase at all costs the number of ICU beds, thereby creating stepdown ICUs; to organize transfer to distant ICUs with more beds available, or to accelerate withdrawal of life support in ICUs. Additionally, to protect the patients'' relatives, visits for families were prohibited or strongly limited and adequate communication between caregivers and families was disrupted, counteracting more than 20 years of research aimed at improving interaction with families and quality of care during EOL [1] .

abstract:
  The devastating pandemic that has stricken the worldwide population induced an unprecedented influx of patients in ICUs, raising ethical concerns not only surrounding triage and withdrawal of life support decisions, but also regarding family visits and quality of end-of-life support. These ingredients are liable to shake up our ethical principles, sharpen our ethical dilemmas, and lead to situations of major caregiver sufferings. Proposals have been made to rationalize triage policies in conjunction with ethical justifications. However, whatever the angle of approach, imbalance between utilitarian and individual ethics leads to unsolvable discomforts that caregivers will need to overcome. With this in mind, we aimed to point out some critical ethical choices with which ICU caregivers have been confronted during the Covid-19 pandemic and to underline their limits. The formalized strategies integrating the relevant tools of ethical reflection were disseminated without deviating from usual practices, leaving to intensivists the ultimate choice of decision.


id: cord-346182-61i4jjys
title: Frontline Workers in the Backrooms of COVID-19: Caring for the Living and the Dead
author: Myers, Jeffrey L
date: 2020-06-17
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url: https://www.ncbi.nlm.nih.gov/pubmed/32556078/
doi: 10.1093/ajcp/aqaa106
summary:
  Through all of this, the forensics teams-pathologists, investigators, laboratory professionals, photographers, social workers, autopsy and pathologist assistants, and administrative staff-have been at the frontline of pathology''s largest COVID-19 front, contributing to the public welfare and the science of SARS-CoV-2 while caring for the dead and the living with a measure of compassion and kindness that few understand or know. During the COVID-19 pandemic, the forensic pathology program at the University of Michigan proved critical to supporting the counties they serve and families of the COVID-19 patients and others who died at home and in hospitals. Individuals in Michigan Medicine''s 4 county forensic services who died of conditions other than SARS-CoV-2 ❚Image 2❚ A large team at the Wayne County Medical Examiner''s Office in Detroit is responsible for autopsies each day and comprises a combination of Michigan Medicine staff (including pathologists'' assistants), trainees, and a faculty member who functions as officer of the day.

abstract:
  OBJECTIVES: To review the response to the coronavirus disease 2019 (COVID-19) pandemic in a forensics center that integrates an academic department of pathology with multiple regional county medical examiners’ offices. METHODS: Faculty and staff were asked to volunteer stories, data, and photographs describing their activities from March through May 2020. The information was assembled into a narrative summary. RESULTS: Increased deaths challenged capacity limits in a hospital morgue and a large urban medical examiner’s office (MEO) successfully managed by forensic teams and monitored by an institutional command center. Autopsies of suspected and proven cases of COVID-19 were performed in both facilities. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing of decedents was performed in a MEO serving a large urban area. Scene investigators worked directly with families to meet needs unique to a pandemic. Artful photographs of decedent’s hands and/or tattoos were offered to those unable to have in-person viewings. Pathologists and social workers were available to families of the deceased and created novel solutions to facilitate the grieving process. CONCLUSIONS: Forensic pathology is important to successfully navigating emerging diseases like the COVID-19 pandemic. Direct conversations with families are common in forensic pathology and serve as a model for patient- and family-centered care.


id: cord-347105-my9nioko
author: Foster, Carolyn C.
date: 2020-10-20
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url: https://www.ncbi.nlm.nih.gov/pubmed/33079264/
doi: 10.1007/s00246-020-02489-7
summary:
  So, while these tools provide important care delivery options, home surveillance based on asynchronous teleIHM and V/P sharing alone may still result in frequent patient travel for routine in-person evaluations or necessitate family-provider phone calls to discuss or clarify asynchronously collected information. For limited English Proficiency families, translation was provided by an interpreter who was placed on speaker phone by the cardiac provider during the VVs. The Integrated Multimodality Telemedicine Care Model for Infants During the Interstage Period is shown in Fig. 1 demonstrating the high-level integration of VVs with teleIHM and V/P sharing for patients followed in the interstage program. This evaluation found that the integration of scheduled, routine VVs with remote home monitoring (teleIHM) through a multidisciplinary advanced practice model can feasibly enhance the care of in infants during the interstage period with overall high family acceptability.

title:
  Integrated Multimodality Telemedicine to Enhance In-Home Care of Infants During the Interstage Period

abstract:
  Performing interstage home monitoring using digital platforms (teleIHM) is becoming commonplace but, when used alone, may still require frequent travel for in-person care. We evaluated the acceptability, feasibility, and added value of integrating teleIHM with synchronous telemedicine video visits (VVs) and asynchronous video/photo sharing (V/P) during the interstage period. We conducted a descriptive program evaluation of patient-families receiving integrated multimodality telemedicine (teleIHM + VV + V/P) interstage care from 7/15/2018 to 05/15/2020. First, provider focus groups were conducted to develop a program logic model. Second, patient characteristics and clinical course were reviewed and analyzed with univariate statistics. Third, semi-structured qualitative interviews of family caregivers’ experiences were assessed using applied thematic analysis. Within the study period, 41 patients received teleIHM + VV + V/P care, of which 6 were still interstage and 4 died. About half (51%) of patients were female and 54% were a racial/ethnic minority. Median age was 42 days old (IQR 25, 58) at interstage start, with a median of 113 total days (IQR 72, 151). A total of 551 VVs were conducted with a median 12 VVs (IQR 7, 18) per patient. Parents sent a median 2 pictures (IQR 0–3, range 0–82). Qualitatively, families reported an adjustment period to teleIHM, but engaged favorably with telemedicine overall. Families felt reassured by the oversight routine telemedicine provided and identified logistical and clinical value to VVs above teleIHM alone, while acknowledging trade-offs with in-person care. Integration of multimodality telemedicine is a feasible and acceptable approach to enhance in-home care during the interstage period.


id: cord-349353-2ll9hzfr
title: Freedom or money? The dilemma of migrant live‐in elderly carers in times of COVID‐19
author: Giordano, Chiara
date: 2020-07-04
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url: https://www.ncbi.nlm.nih.gov/pubmed/32837020/
doi: 10.1111/gwao.12509
abstract: nan
summary:
  Concerning the latter, as it has repeatedly been stressed, the COVID-19 crisis has and will have an impact on various aspects of gender equality, including the economic hardship falling on women whose economic position is precarious, which is the case of many single-parent households; the sharpening of domestic violence; the hazardous situation of workers in the frontline, the majority of whom are women; and the increased burden of unpaid care and housework responsibilities during the lockdown period 1 . Both elementsthe emotional ties between caregiver and care receiver and the position of live-in caregivers as ''quasi-family members''have crucial consequences on the lives and choices of live-in elderly carers in times of COVIDAs mentioned in the previous section, the very nature of care work, including the gendered construction of the ideals and values associated to it and the emotional labour that shapes their This article is protected by copyright.


id: cord-352141-y3s8li0v
title: Family‐centred care during a pandemic: The hidden impact of restricting family visits
author: Bouchoucha, Stéphane
date: 2020-06-13
txt: ./txt/cord-352141-y3s8li0v.txt
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url: https://www.ncbi.nlm.nih.gov/pubmed/32533617/
doi: 10.1111/nhs.12748
abstract: nan
summary:
  While it may be too early in the COVID-19 pandemic to realise the potential impact of compassion fatigue and burnout on nurses, evidence collected following the severe acute respiratory syndrome (SARS) epidemic (Maunder et al., 2006) showed that healthcare workers that cared for patients with SARS had higher levels of burnout, psychological distress and post-traumatic stress than other healthcare workers. From what we know about factors that may increase risks of compassion fatigue and burnout, having to limit visits for family members of critical ill and dying patients is likely to also have a negative impact on nurses by increasing their feelings of providing inadequate family-centred care. Restricting family visits, while a necessary measure to decrease the spread of COVID-19 to vulnerable patients and the community, is likely to have negative effects on families and nurses alike and these impacts need to be carefully considered.


id: cord-352468-hi7u4w3q
author: Xu, Xinglong
date: 2020-07-10
txt: ./txt/cord-352468-hi7u4w3q.txt
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url: https://www.ncbi.nlm.nih.gov/pubmed/32650723/
doi: 10.1186/s12875-020-01182-1
summary:
  In this paper, we apply a novel structural equation model to explore effect of interplay between psychological wellbeing, psychological capital and job involvement on family doctor motivation in Shanghai, Nanjing and Beijing in China. The model consisted of the latent variables psychological wellbeing, job involvement, the moderating variable (psychological capital and its constructs i.e. optimism, self-efficacy, resilience, hope) and the dependent variable (performance sustenance) among family doctors in China. The results of this study show that when psychological capital can interact with other job-related attitudes to generates positive and significant results thereby sustaining the performance of family doctors. This study intended to examine the relationship between job involvement, psychological well-being, and performance among family doctors in China. It again considered the influence of the interaction effect of psychological capital on psychological well-being, job involvement leading to performance sustenance on the family doctor system.

title:
  Reconstructing family doctors’ psychological well-being and motivation for effective performance in China: the intervening role of psychological capital

abstract:
  BACKGROUND: Family practice and family doctors are critical part of China’s primary healthcare delivery in a constantly evolving society. As the first point of contact with the medical system, family practices require physically and psychologically sound and a well-motivated family doctors at all times. This is because an error can lead to loss of lives as gatekeepers of the medical system. Our study explored the extent to which positive psychological capital promotes higher performance among family doctors. METHODS: A questionnaire was used to collect data from family doctors in Shanghai, Nanjing, and Beijing. We applied a structural equation analysis to analyze the causal relationship among the variables. RESULTS: We found out that psychological well-being and job involvement significantly influences the performance of family doctors in China. The study also noted that psychological capital moderates the relationship between psychological well-being attainment, job involvement, and performance. CONCLUSIONS: Studies have shown that these pressures affect their well-being considerably. For this reason, a healthcare professional who experiences positive emotions affects the total behavior which culminates into performance.


id: cord-353410-tbmtg88k
author: Sharma, Shreela V.
date: 2020-10-01
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url: https://www.ncbi.nlm.nih.gov/pubmed/33002052/
doi: 10.1371/journal.pone.0240009
summary:
  Due to COVID-19-related school closures, states were under "shelter in place" orders, and Brighter Bites administered a rapid assessment survey to identify social needs among their families. While overall results of the qualitative thematic analysis for the n = 1048 participants are presented elsewhere (Sharma et al., under review) , a qualitative analysis of participant responses in the high-risk group revealed four major themes presented in Table 2 : fear of contracting COVID-19, disruption of employment status, financial hardship, and exacerbated food insecurity. Conducting a COVID-19 rapid response survey was a purposeful decision on part of Brighter Bites to identify those with highest need during this time of crisis and develop a framework to immediately address a variety of social needs among those in the "high risk" category.

title:
  Using a rapid assessment methodology to identify and address immediate needs among low-income households with children during COVID-19

abstract:
  OBJECTIVE: Brighter Bites is a school-based health promotion program that delivers fresh produce and nutrition education to low-income children and families. Due to COVID-19-related school closures, states were under “shelter in place” orders, and Brighter Bites administered a rapid assessment survey to identify social needs among their families. The purpose of this study is to demonstrate the methodology used to identify those with greatest social needs during this time (“high risk”), and to describe the response of Brighter Bites to these “high risk” families. METHODS: The rapid assessment survey was collected in April 2020 across Houston, Dallas, Washington DC, and Southwest Florida. The survey consisted of items on disruption of employment status, financial hardship, food insecurity, perceived health status and sociodemographics. The open-ended question “Please share your greatest concern at this time, or any other thoughts you would like to share with us.” was asked at the end of each survey to triage “high risk” families. Responses were then used to articulate a response to meet the needs of these high risk families. RESULTS: A total of 1048 families completed the COVID-19 rapid response survey, of which 71 families were triaged and classified as “high risk” (6.8% of survey respondents). During this time, 100% of the “high risk” participants reported being food insecure, 85% were concerned about their financial stability, 82% concerned about the availability of food, and 65% concerned about the affordability of food. A qualitative analysis of the high-risk group revealed four major themes: fear of contracting COVID19, disruption of employment status, financial hardship, and exacerbated food insecurity. In response, Brighter Bites pivoted, created, and deployed a framework to immediately address a variety of social needs among those in the “high risk” category. Administering a rapid response survey to identify the immediate needs of their families can help social service providers tailor their services to meet the needs of the most vulnerable.


id: cord-353438-6bx9lsc7
title: The COVID-19 Pandemic: A Family Affair
author: nan
date: 2020-05-19
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url: https://doi.org/10.1177/1074840720920883
doi: 10.1177/1074840720920883
abstract: nan
summary:
  Residents in long-term care facilities miss their partners and children who are no longer allowed to visit because of the COVID-19 policies to contain the spread of the coronavirus. Distressing stories abound of patients who have to deal with the news of their COVID-19 diagnosis all by themselves without a family member present and those patients who are admitted to an intensive care unit (ICU) who have to say goodbye to their family in the emergency department not knowing whether they will see each other again. Mothers, fathers, and other family members of children receiving psychiatric care report being unable visit their child for an extended period of time and are afraid their child will become ill from the coronavirus. Moreover, as a result of the COVID-19 crisis, much, if not all, of the support given to families who provide long-term care for an ill parent, partner, or child is lost.


id: cord-354194-hf5ndv5f
title: Prioritizing Communication in the Provision of Palliative Care for the Trauma Patient
author: Cook, Mackenzie
date: 2020-10-29
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url: https://doi.org/10.1007/s40719-020-00201-x
doi: 10.1007/s40719-020-00201-x
summary:
  Communicating clearly as part of providing high-quality palliative care in the intensive care unit (ICU) is about guiding difficult decisions, defining goals of care, explaining the impact of acute surgical problems on future quality of life, and facilitating transitions to end of life care [2, 3] . Given that the vast majority of severely injured trauma patients in the ICU have limited abilities to function as their own decision makers, this discussion will primarily focus on the interactions with family and surrogate decision makers as this is the group most in need of high-quality communication [6, 37] . The routine integration of trained palliative care subspecialists in the ICU has been associated with improved quality of life, higher rates of formal advance directives, and greater utilization of hospice service as well as less frequent use of certain non-beneficial life-prolonging treatments for critically ill patients at the end of life [49] .

abstract:
  PURPOSE OF REVIEW: Communication skills in the ICU are an essential part of the care of trauma patients. The goal of this review is to summarize key aspects of our understanding of communication with injured patients in the ICU. RECENT FINDINGS: The need to communicate effectively and empathetically with patients and identify primary goals of care is an essential part of trauma care in the ICU. The optimal design to support complex communication in the ICU will be dependent on institutional experience and resources. The best/worst/most likely model provides a structural model for communication. SUMMARY: We have an imperative to improve the communication for all patients, not just those at the end of their life. A structured approach is important as is involving family at all stages of care. Communication skills can and should be taught to trainees.


id: cord-354941-0ocsf255
author: Amorin‐Woods, Deisy
date: 2020-06-08
txt: ./txt/cord-354941-0ocsf255.txt
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url: https://doi.org/10.1002/anzf.1416
doi: 10.1002/anzf.1416
summary:
  This paper offers a collection of reflections by systemic and family therapists from diverse cultures and contexts penned in the midst of the pandemic. I felt as if these early collections merged into one, represent the ''holding, healing space'' that we as therapists need, before we dare consider what life may look like on the ''other side.'' Without this, how could we support our clients in putting themselves, their families, and their lives back together, in even contemplating what a world of ''functionality'' or ''normality'' may look like? It is crucial that we are able to name and process our experiences in order to support our Global Family Therapists reflect on COVID-19 ª 2020 Australian Association of Family Therapy clients to do the same, in order to provide the holding space they need, and joining-in with them (Minuchin, 1974) .

title:
  Family Therapy and COVID‐19: International Reflections during the Pandemic from Systemic Therapists across the Globe

abstract:
  The COVID‐19 pandemic has convulsed human communities across the globe like no previous event in history. Family therapists, paradoxically, given the core of their work is with systems, are also experiencing upheaval in professional and personal lives, trying to work amidst a society in chaos. This paper offers a collection of reflections by systemic and family therapists from diverse cultures and contexts penned in the midst of the pandemic. The main intention in distilling these narratives is to preserve the ‘cultural diversity’ and ‘ecological position’ of the contributors, guided by phenomenology, cultural ecology, and systemic worldviews of ‘experiencing.’ The second intention is to ‘unite’ promoting solidarity in this isolating situation by bringing each story together, creating its own metaphor of a family: united, connected, stronger. As a cross‐cultural family practitioner, with a strong mission for collaboration, the lead author acknowledges the importance of Context – the nation and location of the experience; Culture – the manner in which culture impacts on experience; Collaboration – enhancing partnership, enriching knowledge, and mapping the journey’s direction; and Connectedness – combating isolation while enhancing unity. Since the key transmission of culture is through language, raw reflections were sought initially in the practitioners’ own language, which were translated for an English‐speaking readership. These narratives are honest and rich descriptions of the authors’ lived experiences, diverse and distinctive. The contributors trust colleagues will find these reflections helpful, validating and acknowledging the challenges of this unique period in history.


