id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-316181-ccauw70y	Yang, Fude	Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology	2017-05-16		.txt	text/plain	5712	305	35	Crude extracts and pure compounds isolated from Radix Bupleuri exhibited various biological activities, such as anti-inflammatory, anticancer, antipyretic, antimicrobial, antiviral, hepatoprotective, neuroprotective, and immunomodulatory effects. Pharmacokinetic studies have demonstrated that the major bioactive compounds (saikosaponins a, b(2), c, and d) were absorbed rapidly in rats after oral administration of the extract of Radix Bupleuri. Triterpenoid saponins are the main active components of Radix Bupleuri, which exhibit a broad spectrum of biological and pharmacological effects, including analgesic, immunomodulatory, hepatoprotective, immunomodulatory, anti-inflammatory, antitumor, and antiviral activities [3, [41] [42] [43] . reported that saikosaponins from Radix Bupleuri exhibited anti-inflammatory activity on inflammatory processes including inhibition of inflammatory exudation, capillary permeability, inflammatory mediators release, migration of white cells, connective tissue hyperplasia, and a variety of allergic inflammation [67] . Saponins isolated from Radix Bupleuri also exhibited significantly anti-proliferative activity in human non-small cell lung cancer A549 cells through Fas-dependent apoptotic pathway [80] .	./cache/cord-316181-ccauw70y.txt	./txt/cord-316181-ccauw70y.txt