id author title date pages extension mime words sentences flesch summary cache txt cord-030027-273pjajl Moriconi, Eleonora Neuroendocrine and Metabolic Effects of Low-Calorie and Non-Calorie Sweeteners 2020-07-16 .txt text/plain 11337 568 42 Therefore, future studies will need to elucidate the potential beneficial and/or detrimental effects of different types of sweeteners on metabolic health (energy balance, appetite, body weight, cardiometabolic risk factors) in healthy subjects and patients with diabetes, obesity and metabolic syndrome. On the basis of the recent findings on the effects of sucralose (129) , the association of non-calorie sweeteners to a very low-carbohydrate nutritional regimen represents a valid approach to prevent the detrimental metabolic effects on insulin sensitivity and the altered neural response to sugars induced by an excessive carbohydrate consumption (Figure 1 ). non-calorie sweeteners) can result in significant beneficial or detrimental effects on energy balance, appetite, body weight, and/or cardiometabolic risk factors in healthy subjects and patients with metabolic diseases (particularly obesity and type 2 diabetes). ./cache/cord-030027-273pjajl.txt ./txt/cord-030027-273pjajl.txt