id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-334511-lx9608vy	Emwas, Abdul-Hamid	NMR as a “Gold Standard” Method in Drug Design and Discovery	2020-10-09		.txt	text/plain	29224	1507	47	The nearly ubiquitous use of virtual screening is due to its efficiency in searching massive chemical databases in order to generate lead molecules [313] that inhibit protein-protein interactions [314] , and its ability to help identity ligand (drug) binding sites on the target of interest [310] to lend insight to the mechanisms of action for lead compounds [315, 316] . The nearly ubiquitous use of virtual screening is due to its efficiency in searching massive chemical databases in order to generate lead molecules [313] that inhibit protein-protein interactions [314] , and its ability to help identity ligand (drug) binding sites on the target of interest [310] to lend insight to the mechanisms of action for lead compounds [315, 316] . Clearly, combining virtual screening with NMR-based methods is advantageous in studying how ligands (drugs) bind and interact with targets (proteins) of interest. The interactions between targets (proteins) and ligands (small molecules) can be analyzed independently of the biological systems by using 'cell-based' NMR drug design approaches.	./cache/cord-334511-lx9608vy.txt	./txt/cord-334511-lx9608vy.txt