id author title date pages extension mime words sentences flesch summary cache txt cord-001151-mdej7nhj Kumar De, Amit Application of an Amine Functionalized Biopolymer in the Colonic Delivery of Glycyrrhizin: A Design and In Vivo Efficacy Study 2013-05-18 .txt text/plain 5109 271 51 The entrapment efficiency and in vitro drug release were studied in simulated gastric, intestinal, and colonic fluids containing rat cecal contents. The in vitro drug release study was carried out in simulated gastric fluid of pH 1.2, simulated intestinal fluid of pH 6.8, and simulated colonic fluid of pH 7.4 containing rat cecal contents under anaerobic conditions. The drug release studies from the microparticles were carried out in the simulated gastric fluid of pH 1.2, simulated intestinal fluid of pH 6.8, and simulated colonic fluid of pH 7.4 containing rat cecal contents [34, 35] . In the simulated colonic fluid containing rat cecal contents, the drug release was a bit more augmented with an initial burst release common for each of the designed The results predict the drug-polymer ratio to be the key factor for controlling the release. ./cache/cord-001151-mdej7nhj.txt ./txt/cord-001151-mdej7nhj.txt