id sid tid token lemma pos cord-277665-ac8txr3h 1 1 key key NNP cord-277665-ac8txr3h 1 2 : : : cord-277665-ac8txr3h 1 3 cord-277665-ac8txr3h cord-277665-ac8txr3h . cord-277665-ac8txr3h 2 1 authors author NNS cord-277665-ac8txr3h 2 2 : : : cord-277665-ac8txr3h 2 3 Grichko Grichko NNP cord-277665-ac8txr3h 2 4 , , , cord-277665-ac8txr3h 2 5 Varvara Varvara NNP cord-277665-ac8txr3h 2 6 P. P. NNP cord-277665-ac8txr3h 2 7 ; ; : cord-277665-ac8txr3h 3 1 Shenderova Shenderova NNP cord-277665-ac8txr3h 3 2 , , , cord-277665-ac8txr3h 3 3 Olga Olga NNP cord-277665-ac8txr3h 3 4 A. a. NN cord-277665-ac8txr3h 3 5 title title NN cord-277665-ac8txr3h 3 6 : : : cord-277665-ac8txr3h 3 7 15 15 CD cord-277665-ac8txr3h 3 8 Nanodiamond Nanodiamond NNP cord-277665-ac8txr3h 3 9 Designing design VBG cord-277665-ac8txr3h 3 10 the the DT cord-277665-ac8txr3h 3 11 Bio Bio NNP cord-277665-ac8txr3h 3 12 - - HYPH cord-277665-ac8txr3h 3 13 Platform Platform NNP cord-277665-ac8txr3h 3 14 date date NN cord-277665-ac8txr3h 3 15 : : : cord-277665-ac8txr3h 3 16 2006 2006 CD cord-277665-ac8txr3h 3 17 - - SYM cord-277665-ac8txr3h 3 18 12 12 CD cord-277665-ac8txr3h 3 19 - - SYM cord-277665-ac8txr3h 3 20 31 31 CD cord-277665-ac8txr3h 3 21 journal journal NN cord-277665-ac8txr3h 3 22 : : : cord-277665-ac8txr3h 3 23 Ultrananocrystalline Ultrananocrystalline NNP cord-277665-ac8txr3h 3 24 Diamond Diamond NNP cord-277665-ac8txr3h 3 25 DOI doi NN cord-277665-ac8txr3h 3 26 : : : cord-277665-ac8txr3h 3 27 10.1016 10.1016 CD cord-277665-ac8txr3h 3 28 / / SYM cord-277665-ac8txr3h 3 29 b978 b978 NN cord-277665-ac8txr3h 3 30 - - HYPH cord-277665-ac8txr3h 3 31 081551524 081551524 CD cord-277665-ac8txr3h 3 32 - - HYPH cord-277665-ac8txr3h 3 33 1.50017 1.50017 CD cord-277665-ac8txr3h 3 34 - - SYM cord-277665-ac8txr3h 3 35 2 2 CD cord-277665-ac8txr3h 3 36 sha sha NN cord-277665-ac8txr3h 3 37 : : : cord-277665-ac8txr3h 3 38 21f5b9febaf0951142a43ae9e2c0f7baae21a307 21f5b9febaf0951142a43ae9e2c0f7baae21a307 NNP cord-277665-ac8txr3h 3 39 doc_id doc_id CD cord-277665-ac8txr3h 3 40 : : : cord-277665-ac8txr3h 3 41 277665 277665 CD cord-277665-ac8txr3h 3 42 cord_uid cord_uid NNS cord-277665-ac8txr3h 3 43 : : : cord-277665-ac8txr3h 4 1 ac8txr3h ac8txr3h NN cord-277665-ac8txr3h 5 1 Publisher Publisher NNP cord-277665-ac8txr3h 5 2 Summary Summary NNP cord-277665-ac8txr3h 6 1 This this DT cord-277665-ac8txr3h 6 2 chapter chapter NN cord-277665-ac8txr3h 6 3 discusses discuss VBZ cord-277665-ac8txr3h 6 4 various various JJ cord-277665-ac8txr3h 6 5 methods method NNS cord-277665-ac8txr3h 6 6 of of IN cord-277665-ac8txr3h 6 7 surface surface NN cord-277665-ac8txr3h 6 8 modification modification NN cord-277665-ac8txr3h 6 9 for for IN cord-277665-ac8txr3h 6 10 the the DT cord-277665-ac8txr3h 6 11 development development NN cord-277665-ac8txr3h 6 12 of of IN cord-277665-ac8txr3h 6 13 functionalized functionalize VBN cord-277665-ac8txr3h 6 14 diamond diamond NN cord-277665-ac8txr3h 6 15 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 6 16 for for IN cord-277665-ac8txr3h 6 17 biomedical biomedical JJ cord-277665-ac8txr3h 6 18 applications application NNS cord-277665-ac8txr3h 6 19 . . . cord-277665-ac8txr3h 7 1 To to TO cord-277665-ac8txr3h 7 2 be be VB cord-277665-ac8txr3h 7 3 used use VBN cord-277665-ac8txr3h 7 4 in in IN cord-277665-ac8txr3h 7 5 biomedical biomedical JJ cord-277665-ac8txr3h 7 6 applications application NNS cord-277665-ac8txr3h 7 7 , , , cord-277665-ac8txr3h 7 8 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 7 9 must must MD cord-277665-ac8txr3h 7 10 be be VB cord-277665-ac8txr3h 7 11 biocompatible biocompatible JJ cord-277665-ac8txr3h 7 12 , , , cord-277665-ac8txr3h 7 13 non non JJ cord-277665-ac8txr3h 7 14 - - JJ cord-277665-ac8txr3h 7 15 toxic toxic JJ cord-277665-ac8txr3h 7 16 , , , cord-277665-ac8txr3h 7 17 non non JJ cord-277665-ac8txr3h 7 18 - - JJ cord-277665-ac8txr3h 7 19 detective detective JJ cord-277665-ac8txr3h 7 20 by by IN cord-277665-ac8txr3h 7 21 immune immune JJ cord-277665-ac8txr3h 7 22 systems system NNS cord-277665-ac8txr3h 7 23 , , , cord-277665-ac8txr3h 7 24 and and CC cord-277665-ac8txr3h 7 25 should should MD cord-277665-ac8txr3h 7 26 not not RB cord-277665-ac8txr3h 7 27 induce induce VB cord-277665-ac8txr3h 7 28 side side NN cord-277665-ac8txr3h 7 29 effects effect NNS cord-277665-ac8txr3h 7 30 . . . cord-277665-ac8txr3h 8 1 Size size NN cord-277665-ac8txr3h 8 2 control control NN cord-277665-ac8txr3h 8 3 of of IN cord-277665-ac8txr3h 8 4 particles particle NNS cord-277665-ac8txr3h 8 5 is be VBZ cord-277665-ac8txr3h 8 6 a a DT cord-277665-ac8txr3h 8 7 prerequisite prerequisite NN cord-277665-ac8txr3h 8 8 for for IN cord-277665-ac8txr3h 8 9 biomedical biomedical JJ cord-277665-ac8txr3h 8 10 applications application NNS cord-277665-ac8txr3h 8 11 . . . cord-277665-ac8txr3h 9 1 Carbon carbon NN cord-277665-ac8txr3h 9 2 nanostructures nanostructure NNS cord-277665-ac8txr3h 9 3 span span VBP cord-277665-ac8txr3h 9 4 the the DT cord-277665-ac8txr3h 9 5 same same JJ cord-277665-ac8txr3h 9 6 length length NN cord-277665-ac8txr3h 9 7 scale scale NN cord-277665-ac8txr3h 9 8 as as IN cord-277665-ac8txr3h 9 9 bio bio NN cord-277665-ac8txr3h 9 10 - - NNS cord-277665-ac8txr3h 9 11 compounds compound NNS cord-277665-ac8txr3h 9 12 , , , cord-277665-ac8txr3h 9 13 ranging range VBG cord-277665-ac8txr3h 9 14 from from IN cord-277665-ac8txr3h 9 15 subnanometer subnanometer NN cord-277665-ac8txr3h 9 16 - - HYPH cord-277665-ac8txr3h 9 17 size size NN cord-277665-ac8txr3h 9 18 nucleotides nucleotide NNS cord-277665-ac8txr3h 9 19 to to IN cord-277665-ac8txr3h 9 20 tens ten NNS cord-277665-ac8txr3h 9 21 and and CC cord-277665-ac8txr3h 9 22 hundreds hundred NNS cord-277665-ac8txr3h 9 23 of of IN cord-277665-ac8txr3h 9 24 nanometer nanometer NN cord-277665-ac8txr3h 9 25 - - HYPH cord-277665-ac8txr3h 9 26 sized sized JJ cord-277665-ac8txr3h 9 27 organelles organelle NNS cord-277665-ac8txr3h 9 28 and and CC cord-277665-ac8txr3h 9 29 viruses virus NNS cord-277665-ac8txr3h 9 30 , , , cord-277665-ac8txr3h 9 31 and and CC cord-277665-ac8txr3h 9 32 up up IN cord-277665-ac8txr3h 9 33 to to TO cord-277665-ac8txr3h 9 34 micron micron NN cord-277665-ac8txr3h 9 35 - - HYPH cord-277665-ac8txr3h 9 36 sized sized JJ cord-277665-ac8txr3h 9 37 cell cell NN cord-277665-ac8txr3h 9 38 sizes size NNS cord-277665-ac8txr3h 9 39 . . . cord-277665-ac8txr3h 10 1 The the DT cord-277665-ac8txr3h 10 2 chapter chapter NN cord-277665-ac8txr3h 10 3 also also RB cord-277665-ac8txr3h 10 4 summarizes summarize VBZ cord-277665-ac8txr3h 10 5 different different JJ cord-277665-ac8txr3h 10 6 approaches approach NNS cord-277665-ac8txr3h 10 7 to to IN cord-277665-ac8txr3h 10 8 the the DT cord-277665-ac8txr3h 10 9 surface surface NN cord-277665-ac8txr3h 10 10 functionalization functionalization NN cord-277665-ac8txr3h 10 11 of of IN cord-277665-ac8txr3h 10 12 nanodiamonds nanodiamond NNS cord-277665-ac8txr3h 10 13 ( ( -LRB- cord-277665-ac8txr3h 10 14 ND ND NNP cord-277665-ac8txr3h 10 15 ) ) -RRB- cord-277665-ac8txr3h 10 16 particles particle NNS cord-277665-ac8txr3h 10 17 — — : cord-277665-ac8txr3h 10 18 that that RB cord-277665-ac8txr3h 10 19 is is RB cord-277665-ac8txr3h 10 20 , , , cord-277665-ac8txr3h 10 21 the the DT cord-277665-ac8txr3h 10 22 key key NN cord-277665-ac8txr3h 10 23 in in IN cord-277665-ac8txr3h 10 24 successful successful JJ cord-277665-ac8txr3h 10 25 biomedical biomedical JJ cord-277665-ac8txr3h 10 26 applications application NNS cord-277665-ac8txr3h 10 27 followed follow VBN cord-277665-ac8txr3h 10 28 by by IN cord-277665-ac8txr3h 10 29 a a DT cord-277665-ac8txr3h 10 30 discussion discussion NN cord-277665-ac8txr3h 10 31 of of IN cord-277665-ac8txr3h 10 32 modification modification NN cord-277665-ac8txr3h 10 33 of of IN cord-277665-ac8txr3h 10 34 diamond diamond NN cord-277665-ac8txr3h 10 35 surfaces surface NNS cord-277665-ac8txr3h 10 36 with with IN cord-277665-ac8txr3h 10 37 nucleic nucleic JJ cord-277665-ac8txr3h 10 38 acids acid NNS cord-277665-ac8txr3h 10 39 and and CC cord-277665-ac8txr3h 10 40 proteins protein NNS cord-277665-ac8txr3h 10 41 . . . cord-277665-ac8txr3h 11 1 Both both DT cord-277665-ac8txr3h 11 2 current current JJ cord-277665-ac8txr3h 11 3 and and CC cord-277665-ac8txr3h 11 4 potential potential JJ cord-277665-ac8txr3h 11 5 applications application NNS cord-277665-ac8txr3h 11 6 of of IN cord-277665-ac8txr3h 11 7 diamond diamond NN cord-277665-ac8txr3h 11 8 films film NNS cord-277665-ac8txr3h 11 9 and and CC cord-277665-ac8txr3h 11 10 particles particle NNS cord-277665-ac8txr3h 11 11 in in IN cord-277665-ac8txr3h 11 12 the the DT cord-277665-ac8txr3h 11 13 area area NN cord-277665-ac8txr3h 11 14 of of IN cord-277665-ac8txr3h 11 15 biosensing biosensing NN cord-277665-ac8txr3h 11 16 are be VBP cord-277665-ac8txr3h 11 17 addressed address VBN cord-277665-ac8txr3h 11 18 . . . cord-277665-ac8txr3h 12 1 All all DT cord-277665-ac8txr3h 12 2 major major JJ cord-277665-ac8txr3h 12 3 forms form NNS cord-277665-ac8txr3h 12 4 of of IN cord-277665-ac8txr3h 12 5 carbon carbon NN cord-277665-ac8txr3h 12 6 at at IN cord-277665-ac8txr3h 12 7 the the DT cord-277665-ac8txr3h 12 8 nanoscale nanoscale JJ cord-277665-ac8txr3h 12 9 -fullerenes -fullerene NNS cord-277665-ac8txr3h 12 10 , , , cord-277665-ac8txr3h 12 11 nanotubes nanotube NNS cord-277665-ac8txr3h 12 12 , , , cord-277665-ac8txr3h 12 13 and and CC cord-277665-ac8txr3h 12 14 nanodiamond nanodiamond NNP cord-277665-ac8txr3h 12 15 ( ( -LRB- cord-277665-ac8txr3h 12 16 ND ND NNP cord-277665-ac8txr3h 12 17 ) ) -RRB- cord-277665-ac8txr3h 12 18 , , , cord-277665-ac8txr3h 12 19 the the DT cord-277665-ac8txr3h 12 20 last last JJ cord-277665-ac8txr3h 12 21 in in IN cord-277665-ac8txr3h 12 22 the the DT cord-277665-ac8txr3h 12 23 forms form NNS cord-277665-ac8txr3h 12 24 of of IN cord-277665-ac8txr3h 12 25 both both DT cord-277665-ac8txr3h 12 26 particulate particulate NN cord-277665-ac8txr3h 12 27 and and CC cord-277665-ac8txr3h 12 28 filmsappear filmsappear NN cord-277665-ac8txr3h 12 29 to to TO cord-277665-ac8txr3h 12 30 be be VB cord-277665-ac8txr3h 12 31 valuable valuable JJ cord-277665-ac8txr3h 12 32 materials material NNS cord-277665-ac8txr3h 12 33 for for IN cord-277665-ac8txr3h 12 34 biomedical biomedical JJ cord-277665-ac8txr3h 12 35 applications application NNS cord-277665-ac8txr3h 12 36 ( ( -LRB- cord-277665-ac8txr3h 12 37 Freitas Freitas NNP cord-277665-ac8txr3h 12 38 , , , cord-277665-ac8txr3h 12 39 1999 1999 CD cord-277665-ac8txr3h 12 40 ; ; : cord-277665-ac8txr3h 12 41 . . . cord-277665-ac8txr3h 13 1 Importantly importantly RB cord-277665-ac8txr3h 13 2 , , , cord-277665-ac8txr3h 13 3 carbon carbon NN cord-277665-ac8txr3h 13 4 nanostructures nanostructure NNS cord-277665-ac8txr3h 13 5 span span VBP cord-277665-ac8txr3h 13 6 the the DT cord-277665-ac8txr3h 13 7 same same JJ cord-277665-ac8txr3h 13 8 length length NN cord-277665-ac8txr3h 13 9 scale scale NN cord-277665-ac8txr3h 13 10 as as IN cord-277665-ac8txr3h 13 11 bio bio NN cord-277665-ac8txr3h 13 12 - - HYPH cord-277665-ac8txr3h 13 13 compounds compound NNS cord-277665-ac8txr3h 13 14 ( ( -LRB- cord-277665-ac8txr3h 13 15 Fig Fig NNP cord-277665-ac8txr3h 13 16 . . . cord-277665-ac8txr3h 13 17 15.1 15.1 CD cord-277665-ac8txr3h 13 18 ) ) -RRB- cord-277665-ac8txr3h 13 19 , , , cord-277665-ac8txr3h 13 20 ranging range VBG cord-277665-ac8txr3h 13 21 from from IN cord-277665-ac8txr3h 13 22 subnanometer subnanometer NN cord-277665-ac8txr3h 13 23 - - HYPH cord-277665-ac8txr3h 13 24 size size NN cord-277665-ac8txr3h 13 25 nucleotides nucleotide NNS cord-277665-ac8txr3h 13 26 , , , cord-277665-ac8txr3h 13 27 to to IN cord-277665-ac8txr3h 13 28 tens ten NNS cord-277665-ac8txr3h 13 29 and and CC cord-277665-ac8txr3h 13 30 hundreds hundred NNS cord-277665-ac8txr3h 13 31 of of IN cord-277665-ac8txr3h 13 32 nanometer nanometer NN cord-277665-ac8txr3h 13 33 - - HYPH cord-277665-ac8txr3h 13 34 sized sized JJ cord-277665-ac8txr3h 13 35 organelles organelle NNS cord-277665-ac8txr3h 13 36 and and CC cord-277665-ac8txr3h 13 37 viruses virus NNS cord-277665-ac8txr3h 13 38 , , , cord-277665-ac8txr3h 13 39 and and CC cord-277665-ac8txr3h 13 40 up up IN cord-277665-ac8txr3h 13 41 to to TO cord-277665-ac8txr3h 13 42 micron micron NN cord-277665-ac8txr3h 13 43 - - HYPH cord-277665-ac8txr3h 13 44 sized sized JJ cord-277665-ac8txr3h 13 45 cell cell NN cord-277665-ac8txr3h 13 46 sizes size NNS cord-277665-ac8txr3h 13 47 . . . cord-277665-ac8txr3h 14 1 In in IN cord-277665-ac8txr3h 14 2 the the DT cord-277665-ac8txr3h 14 3 mid mid JJ cord-277665-ac8txr3h 14 4 1990s 1990 NNS cord-277665-ac8txr3h 14 5 it -PRON- PRP cord-277665-ac8txr3h 14 6 was be VBD cord-277665-ac8txr3h 14 7 discovered discover VBN cord-277665-ac8txr3h 14 8 that that IN cord-277665-ac8txr3h 14 9 fullerene fullerene NN cord-277665-ac8txr3h 14 10 compounds compound NNS cord-277665-ac8txr3h 14 11 have have VBP cord-277665-ac8txr3h 14 12 biological biological JJ cord-277665-ac8txr3h 14 13 activity activity NN cord-277665-ac8txr3h 14 14 , , , cord-277665-ac8txr3h 14 15 and and CC cord-277665-ac8txr3h 14 16 their -PRON- PRP$ cord-277665-ac8txr3h 14 17 potential potential NN cord-277665-ac8txr3h 14 18 as as IN cord-277665-ac8txr3h 14 19 therapeutic therapeutic JJ cord-277665-ac8txr3h 14 20 agents agent NNS cord-277665-ac8txr3h 14 21 for for IN cord-277665-ac8txr3h 14 22 the the DT cord-277665-ac8txr3h 14 23 treatment treatment NN cord-277665-ac8txr3h 14 24 of of IN cord-277665-ac8txr3h 14 25 several several JJ cord-277665-ac8txr3h 14 26 diseases disease NNS cord-277665-ac8txr3h 14 27 was be VBD cord-277665-ac8txr3h 14 28 demonstrated demonstrate VBN cord-277665-ac8txr3h 14 29 . . . cord-277665-ac8txr3h 15 1 As as IN cord-277665-ac8txr3h 15 2 a a DT cord-277665-ac8txr3h 15 3 result result NN cord-277665-ac8txr3h 15 4 , , , cord-277665-ac8txr3h 15 5 a a DT cord-277665-ac8txr3h 15 6 private private JJ cord-277665-ac8txr3h 15 7 biopharmaceutical biopharmaceutical JJ cord-277665-ac8txr3h 15 8 company company NN cord-277665-ac8txr3h 15 9 , , , cord-277665-ac8txr3h 15 10 C C NNP cord-277665-ac8txr3h 15 11 Sixty Sixty NNP cord-277665-ac8txr3h 15 12 Inc. Inc. NNP cord-277665-ac8txr3h 15 13 , , , cord-277665-ac8txr3h 15 14 has have VBZ cord-277665-ac8txr3h 15 15 been be VBN cord-277665-ac8txr3h 15 16 established establish VBN cord-277665-ac8txr3h 15 17 with with IN cord-277665-ac8txr3h 15 18 a a DT cord-277665-ac8txr3h 15 19 primary primary JJ cord-277665-ac8txr3h 15 20 focus focus NN cord-277665-ac8txr3h 15 21 on on IN cord-277665-ac8txr3h 15 22 the the DT cord-277665-ac8txr3h 15 23 discovery discovery NN cord-277665-ac8txr3h 15 24 and and CC cord-277665-ac8txr3h 15 25 development development NN cord-277665-ac8txr3h 15 26 of of IN cord-277665-ac8txr3h 15 27 novel novel JJ cord-277665-ac8txr3h 15 28 fullerene fullerene NN cord-277665-ac8txr3h 15 29 - - HYPH cord-277665-ac8txr3h 15 30 based base VBN cord-277665-ac8txr3h 15 31 therapeutics therapeutic NNS cord-277665-ac8txr3h 15 32 . . . cord-277665-ac8txr3h 16 1 At at IN cord-277665-ac8txr3h 16 2 7.2 7.2 CD cord-277665-ac8txr3h 16 3 Å å NN cord-277665-ac8txr3h 16 4 in in IN cord-277665-ac8txr3h 16 5 diameter diameter NN cord-277665-ac8txr3h 16 6 , , , cord-277665-ac8txr3h 16 7 C C NNP cord-277665-ac8txr3h 16 8 60 60 CD cord-277665-ac8txr3h 16 9 is be VBZ cord-277665-ac8txr3h 16 10 similar similar JJ cord-277665-ac8txr3h 16 11 in in IN cord-277665-ac8txr3h 16 12 size size NN cord-277665-ac8txr3h 16 13 to to IN cord-277665-ac8txr3h 16 14 steroid steroid NN cord-277665-ac8txr3h 16 15 hormones hormone NNS cord-277665-ac8txr3h 16 16 and and CC cord-277665-ac8txr3h 16 17 peptide peptide JJ cord-277665-ac8txr3h 16 18 alpha alpha NN cord-277665-ac8txr3h 16 19 - - HYPH cord-277665-ac8txr3h 16 20 helices helix NNS cord-277665-ac8txr3h 16 21 , , , cord-277665-ac8txr3h 16 22 and and CC cord-277665-ac8txr3h 16 23 , , , cord-277665-ac8txr3h 16 24 thus thus RB cord-277665-ac8txr3h 16 25 , , , cord-277665-ac8txr3h 16 26 fullerene fullerene NN cord-277665-ac8txr3h 16 27 compounds compound NNS cord-277665-ac8txr3h 16 28 are be VBP cord-277665-ac8txr3h 16 29 ideal ideal JJ cord-277665-ac8txr3h 16 30 molecules molecule NNS cord-277665-ac8txr3h 16 31 to to TO cord-277665-ac8txr3h 16 32 serve serve VB cord-277665-ac8txr3h 16 33 as as IN cord-277665-ac8txr3h 16 34 ligands ligand NNS cord-277665-ac8txr3h 16 35 for for IN cord-277665-ac8txr3h 16 36 enzymes enzyme NNS cord-277665-ac8txr3h 16 37 and and CC cord-277665-ac8txr3h 16 38 receptors receptor NNS cord-277665-ac8txr3h 16 39 ( ( -LRB- cord-277665-ac8txr3h 16 40 Wilson Wilson NNP cord-277665-ac8txr3h 16 41 , , , cord-277665-ac8txr3h 16 42 2000 2000 CD cord-277665-ac8txr3h 16 43 ) ) -RRB- cord-277665-ac8txr3h 16 44 . . . cord-277665-ac8txr3h 17 1 Within within IN cord-277665-ac8txr3h 17 2 the the DT cord-277665-ac8txr3h 17 3 last last JJ cord-277665-ac8txr3h 17 4 few few JJ cord-277665-ac8txr3h 17 5 years year NNS cord-277665-ac8txr3h 17 6 , , , cord-277665-ac8txr3h 17 7 a a DT cord-277665-ac8txr3h 17 8 number number NN cord-277665-ac8txr3h 17 9 of of IN cord-277665-ac8txr3h 17 10 useful useful JJ cord-277665-ac8txr3h 17 11 fullerene fullerene NN cord-277665-ac8txr3h 17 12 - - HYPH cord-277665-ac8txr3h 17 13 based base VBN cord-277665-ac8txr3h 17 14 therapeutic therapeutic JJ cord-277665-ac8txr3h 17 15 applications application NNS cord-277665-ac8txr3h 17 16 have have VBP cord-277665-ac8txr3h 17 17 been be VBN cord-277665-ac8txr3h 17 18 developed develop VBN cord-277665-ac8txr3h 17 19 , , , cord-277665-ac8txr3h 17 20 including include VBG cord-277665-ac8txr3h 17 21 as as IN cord-277665-ac8txr3h 17 22 antiviral antiviral JJ cord-277665-ac8txr3h 17 23 agents agent NNS cord-277665-ac8txr3h 17 24 and and CC cord-277665-ac8txr3h 17 25 anticancer anticancer JJ cord-277665-ac8txr3h 17 26 drugs drug NNS cord-277665-ac8txr3h 17 27 ( ( -LRB- cord-277665-ac8txr3h 17 28 www.csixty.com www.csixty.com ADD cord-277665-ac8txr3h 17 29 ) ) -RRB- cord-277665-ac8txr3h 17 30 and and CC cord-277665-ac8txr3h 17 31 biosensors biosensor NNS cord-277665-ac8txr3h 17 32 for for IN cord-277665-ac8txr3h 17 33 diagnostic diagnostic JJ cord-277665-ac8txr3h 17 34 applications application NNS cord-277665-ac8txr3h 17 35 ( ( -LRB- cord-277665-ac8txr3h 17 36 Anonymous Anonymous NNP cord-277665-ac8txr3h 17 37 , , , cord-277665-ac8txr3h 17 38 2001 2001 CD cord-277665-ac8txr3h 17 39 ) ) -RRB- cord-277665-ac8txr3h 17 40 ; ; : cord-277665-ac8txr3h 17 41 a a DT cord-277665-ac8txr3h 17 42 protective protective JJ cord-277665-ac8txr3h 17 43 agent agent NN cord-277665-ac8txr3h 17 44 against against IN cord-277665-ac8txr3h 17 45 iron iron NN cord-277665-ac8txr3h 17 46 - - HYPH cord-277665-ac8txr3h 17 47 induced induce VBN cord-277665-ac8txr3h 17 48 oxidative oxidative JJ cord-277665-ac8txr3h 17 49 stress stress NN cord-277665-ac8txr3h 17 50 ( ( -LRB- cord-277665-ac8txr3h 17 51 Lin Lin NNP cord-277665-ac8txr3h 17 52 et et NNP cord-277665-ac8txr3h 17 53 al al NNP cord-277665-ac8txr3h 17 54 . . NNP cord-277665-ac8txr3h 17 55 , , , cord-277665-ac8txr3h 17 56 1999 1999 CD cord-277665-ac8txr3h 17 57 ) ) -RRB- cord-277665-ac8txr3h 17 58 ; ; : cord-277665-ac8txr3h 17 59 and and CC cord-277665-ac8txr3h 17 60 an an DT cord-277665-ac8txr3h 17 61 in in FW cord-277665-ac8txr3h 17 62 vitro vitro FW cord-277665-ac8txr3h 17 63 antibacterial antibacterial JJ cord-277665-ac8txr3h 17 64 agent agent NN cord-277665-ac8txr3h 17 65 ( ( -LRB- cord-277665-ac8txr3h 17 66 Da Da NNP cord-277665-ac8txr3h 17 67 Ros Ros NNP cord-277665-ac8txr3h 17 68 et et NNP cord-277665-ac8txr3h 17 69 al al NNP cord-277665-ac8txr3h 17 70 . . NNP cord-277665-ac8txr3h 17 71 , , , cord-277665-ac8txr3h 17 72 1996 1996 CD cord-277665-ac8txr3h 17 73 ) ) -RRB- cord-277665-ac8txr3h 17 74 . . . cord-277665-ac8txr3h 18 1 The the DT cord-277665-ac8txr3h 18 2 exploration exploration NN cord-277665-ac8txr3h 18 3 of of IN cord-277665-ac8txr3h 18 4 buckytubes buckytubes NNP cord-277665-ac8txr3h 18 5 in in IN cord-277665-ac8txr3h 18 6 biomedical biomedical JJ cord-277665-ac8txr3h 18 7 applications application NNS cord-277665-ac8txr3h 18 8 is be VBZ cord-277665-ac8txr3h 18 9 also also RB cord-277665-ac8txr3h 18 10 underway underway JJ cord-277665-ac8txr3h 18 11 . . . cord-277665-ac8txr3h 19 1 Multiwall Multiwall NNP cord-277665-ac8txr3h 19 2 carbon carbon NN cord-277665-ac8txr3h 19 3 nanotubes nanotube NNS cord-277665-ac8txr3h 19 4 have have VBP cord-277665-ac8txr3h 19 5 been be VBN cord-277665-ac8txr3h 19 6 used use VBN cord-277665-ac8txr3h 19 7 for for IN cord-277665-ac8txr3h 19 8 immobilization immobilization NN cord-277665-ac8txr3h 19 9 of of IN cord-277665-ac8txr3h 19 10 proteins protein NNS cord-277665-ac8txr3h 19 11 , , , cord-277665-ac8txr3h 19 12 enzymes enzyme NNS cord-277665-ac8txr3h 19 13 , , , cord-277665-ac8txr3h 19 14 and and CC cord-277665-ac8txr3h 19 15 oligonucleotides oligonucleotide NNS cord-277665-ac8txr3h 19 16 ( ( -LRB- cord-277665-ac8txr3h 19 17 Lin Lin NNP cord-277665-ac8txr3h 19 18 et et NNP cord-277665-ac8txr3h 19 19 al al NNP cord-277665-ac8txr3h 19 20 . . NNP cord-277665-ac8txr3h 19 21 , , , cord-277665-ac8txr3h 19 22 2004 2004 CD cord-277665-ac8txr3h 19 23 ) ) -RRB- cord-277665-ac8txr3h 19 24 . . . cord-277665-ac8txr3h 20 1 Significant significant JJ cord-277665-ac8txr3h 20 2 progress progress NN cord-277665-ac8txr3h 20 3 has have VBZ cord-277665-ac8txr3h 20 4 been be VBN cord-277665-ac8txr3h 20 5 made make VBN cord-277665-ac8txr3h 20 6 within within IN cord-277665-ac8txr3h 20 7 the the DT cord-277665-ac8txr3h 20 8 last last JJ cord-277665-ac8txr3h 20 9 few few JJ cord-277665-ac8txr3h 20 10 years year NNS cord-277665-ac8txr3h 20 11 in in IN cord-277665-ac8txr3h 20 12 an an DT cord-277665-ac8txr3h 20 13 effort effort NN cord-277665-ac8txr3h 20 14 to to TO cord-277665-ac8txr3h 20 15 overcome overcome VB cord-277665-ac8txr3h 20 16 some some DT cord-277665-ac8txr3h 20 17 of of IN cord-277665-ac8txr3h 20 18 the the DT cord-277665-ac8txr3h 20 19 fundamental fundamental JJ cord-277665-ac8txr3h 20 20 and and CC cord-277665-ac8txr3h 20 21 technical technical JJ cord-277665-ac8txr3h 20 22 barriers barrier NNS cord-277665-ac8txr3h 20 23 toward toward IN cord-277665-ac8txr3h 20 24 bioapplications bioapplication NNS cord-277665-ac8txr3h 20 25 of of IN cord-277665-ac8txr3h 20 26 carbon carbon NN cord-277665-ac8txr3h 20 27 nanotubes nanotube NNS cord-277665-ac8txr3h 20 28 , , , cord-277665-ac8txr3h 20 29 especially especially RB cord-277665-ac8txr3h 20 30 on on IN cord-277665-ac8txr3h 20 31 issues issue NNS cord-277665-ac8txr3h 20 32 concerning concern VBG cord-277665-ac8txr3h 20 33 solubility solubility NN cord-277665-ac8txr3h 20 34 in in IN cord-277665-ac8txr3h 20 35 water water NN cord-277665-ac8txr3h 20 36 , , , cord-277665-ac8txr3h 20 37 biocompatibility biocompatibility NN cord-277665-ac8txr3h 20 38 , , , cord-277665-ac8txr3h 20 39 modifications modification NNS cord-277665-ac8txr3h 20 40 of of IN cord-277665-ac8txr3h 20 41 carbon carbon NN cord-277665-ac8txr3h 20 42 nanotubes nanotube NNS cord-277665-ac8txr3h 20 43 with with IN cord-277665-ac8txr3h 20 44 various various JJ cord-277665-ac8txr3h 20 45 biological biological JJ cord-277665-ac8txr3h 20 46 and and CC cord-277665-ac8txr3h 20 47 biologically biologically RB cord-277665-ac8txr3h 20 48 active active JJ cord-277665-ac8txr3h 20 49 compounds compound NNS cord-277665-ac8txr3h 20 50 , , , cord-277665-ac8txr3h 20 51 and and CC cord-277665-ac8txr3h 20 52 both both DT cord-277665-ac8txr3h 20 53 design design NN cord-277665-ac8txr3h 20 54 and and CC cord-277665-ac8txr3h 20 55 fabrication fabrication NN cord-277665-ac8txr3h 20 56 of of IN cord-277665-ac8txr3h 20 57 biosensor biosensor NN cord-277665-ac8txr3h 20 58 prototypes prototype NNS cord-277665-ac8txr3h 21 1 ( ( -LRB- cord-277665-ac8txr3h 21 2 Lin Lin NNP cord-277665-ac8txr3h 21 3 et et NNP cord-277665-ac8txr3h 21 4 al al NNP cord-277665-ac8txr3h 21 5 . . NNP cord-277665-ac8txr3h 21 6 , , , cord-277665-ac8txr3h 21 7 2004 2004 CD cord-277665-ac8txr3h 21 8 ) ) -RRB- cord-277665-ac8txr3h 21 9 . . . cord-277665-ac8txr3h 22 1 Nanodiamond Nanodiamond NNP cord-277665-ac8txr3h 22 2 particles particle NNS cord-277665-ac8txr3h 22 3 and and CC cord-277665-ac8txr3h 22 4 their -PRON- PRP$ cord-277665-ac8txr3h 22 5 derivatives derivative NNS cord-277665-ac8txr3h 22 6 , , , cord-277665-ac8txr3h 22 7 diamondoids diamondoids NNP cord-277665-ac8txr3h 22 8 and and CC cord-277665-ac8txr3h 22 9 their -PRON- PRP$ cord-277665-ac8txr3h 22 10 derivatives derivative NNS cord-277665-ac8txr3h 22 11 , , , cord-277665-ac8txr3h 22 12 and and CC cord-277665-ac8txr3h 22 13 ultrananocrystalline ultrananocrystalline JJ cord-277665-ac8txr3h 22 14 diamond diamond NN cord-277665-ac8txr3h 22 15 ( ( -LRB- cord-277665-ac8txr3h 22 16 UNCD UNCD NNP cord-277665-ac8txr3h 22 17 ) ) -RRB- cord-277665-ac8txr3h 22 18 films film NNS cord-277665-ac8txr3h 22 19 all all DT cord-277665-ac8txr3h 22 20 have have VBP cord-277665-ac8txr3h 22 21 high high JJ cord-277665-ac8txr3h 22 22 potential potential NN cord-277665-ac8txr3h 22 23 in in IN cord-277665-ac8txr3h 22 24 biotechnological biotechnological JJ cord-277665-ac8txr3h 22 25 and and CC cord-277665-ac8txr3h 22 26 biomedical biomedical JJ cord-277665-ac8txr3h 22 27 applications application NNS cord-277665-ac8txr3h 22 28 . . . cord-277665-ac8txr3h 23 1 UNCD UNCD NNP cord-277665-ac8txr3h 23 2 films film NNS cord-277665-ac8txr3h 23 3 have have VBP cord-277665-ac8txr3h 23 4 been be VBN cord-277665-ac8txr3h 23 5 suggested suggest VBN cord-277665-ac8txr3h 23 6 to to TO cord-277665-ac8txr3h 23 7 be be VB cord-277665-ac8txr3h 23 8 the the DT cord-277665-ac8txr3h 23 9 ideal ideal JJ cord-277665-ac8txr3h 23 10 platforms platform NNS cord-277665-ac8txr3h 23 11 for for IN cord-277665-ac8txr3h 23 12 future future JJ cord-277665-ac8txr3h 23 13 biochips biochip NNS cord-277665-ac8txr3h 23 14 and and CC cord-277665-ac8txr3h 23 15 biosensors biosensor NNS cord-277665-ac8txr3h 23 16 because because IN cord-277665-ac8txr3h 23 17 of of IN cord-277665-ac8txr3h 23 18 their -PRON- PRP$ cord-277665-ac8txr3h 23 19 superior superior JJ cord-277665-ac8txr3h 23 20 mechanical mechanical JJ cord-277665-ac8txr3h 23 21 , , , cord-277665-ac8txr3h 23 22 thermal thermal JJ cord-277665-ac8txr3h 23 23 , , , cord-277665-ac8txr3h 23 24 and and CC cord-277665-ac8txr3h 23 25 chemical chemical NN cord-277665-ac8txr3h 23 26 properties property NNS cord-277665-ac8txr3h 23 27 as as IN cord-277665-ac8txr3h 23 28 compared compare VBN cord-277665-ac8txr3h 23 29 to to IN cord-277665-ac8txr3h 23 30 those those DT cord-277665-ac8txr3h 23 31 of of IN cord-277665-ac8txr3h 23 32 glass glass NN cord-277665-ac8txr3h 23 33 , , , cord-277665-ac8txr3h 23 34 silicon silicon NN cord-277665-ac8txr3h 23 35 , , , cord-277665-ac8txr3h 23 36 and and CC cord-277665-ac8txr3h 23 37 gold gold NN cord-277665-ac8txr3h 23 38 surfaces surface NNS cord-277665-ac8txr3h 23 39 ( ( -LRB- cord-277665-ac8txr3h 23 40 Yang Yang NNP cord-277665-ac8txr3h 23 41 et et NNP cord-277665-ac8txr3h 23 42 al al NNP cord-277665-ac8txr3h 23 43 . . NNP cord-277665-ac8txr3h 23 44 , , , cord-277665-ac8txr3h 23 45 2002 2002 CD cord-277665-ac8txr3h 23 46 ) ) -RRB- cord-277665-ac8txr3h 23 47 . . . cord-277665-ac8txr3h 24 1 UNCD UNCD NNP cord-277665-ac8txr3h 24 2 particles particle NNS cord-277665-ac8txr3h 24 3 had have VBD cord-277665-ac8txr3h 24 4 been be VBN cord-277665-ac8txr3h 24 5 probed probe VBN cord-277665-ac8txr3h 24 6 in in IN cord-277665-ac8txr3h 24 7 the the DT cord-277665-ac8txr3h 24 8 separation separation NN cord-277665-ac8txr3h 24 9 of of IN cord-277665-ac8txr3h 24 10 proteins protein NNS cord-277665-ac8txr3h 24 11 ( ( -LRB- cord-277665-ac8txr3h 24 12 Bondar Bondar NNP cord-277665-ac8txr3h 24 13 and and CC cord-277665-ac8txr3h 24 14 Puzr Puzr NNP cord-277665-ac8txr3h 24 15 , , , cord-277665-ac8txr3h 24 16 2004 2004 CD cord-277665-ac8txr3h 24 17 ) ) -RRB- cord-277665-ac8txr3h 24 18 , , , cord-277665-ac8txr3h 24 19 fabrication fabrication NN cord-277665-ac8txr3h 24 20 of of IN cord-277665-ac8txr3h 24 21 integrated integrate VBN cord-277665-ac8txr3h 24 22 biochips biochip NNS cord-277665-ac8txr3h 24 23 and and CC cord-277665-ac8txr3h 24 24 sensors sensor NNS cord-277665-ac8txr3h 24 25 ( ( -LRB- cord-277665-ac8txr3h 24 26 Puzyr Puzyr NNP cord-277665-ac8txr3h 24 27 et et NNP cord-277665-ac8txr3h 24 28 al al NNP cord-277665-ac8txr3h 24 29 . . NNP cord-277665-ac8txr3h 24 30 , , , cord-277665-ac8txr3h 24 31 2004a 2004a CD cord-277665-ac8txr3h 24 32 ) ) -RRB- cord-277665-ac8txr3h 24 33 , , , cord-277665-ac8txr3h 24 34 and and CC cord-277665-ac8txr3h 24 35 even even RB cord-277665-ac8txr3h 24 36 in in IN cord-277665-ac8txr3h 24 37 anticancer anticancer JJ cord-277665-ac8txr3h 24 38 applications application NNS cord-277665-ac8txr3h 24 39 ( ( -LRB- cord-277665-ac8txr3h 24 40 Dolmatov Dolmatov NNP cord-277665-ac8txr3h 24 41 , , , cord-277665-ac8txr3h 24 42 2001 2001 CD cord-277665-ac8txr3h 24 43 ) ) -RRB- cord-277665-ac8txr3h 24 44 . . . cord-277665-ac8txr3h 25 1 In in IN cord-277665-ac8txr3h 25 2 general general JJ cord-277665-ac8txr3h 25 3 , , , cord-277665-ac8txr3h 25 4 multifunctional multifunctional JJ cord-277665-ac8txr3h 25 5 hierarchical hierarchical JJ cord-277665-ac8txr3h 25 6 structures structure NNS cord-277665-ac8txr3h 25 7 consisting consist VBG cord-277665-ac8txr3h 25 8 of of IN cord-277665-ac8txr3h 25 9 nanoparticle nanoparticle NN cord-277665-ac8txr3h 25 10 derivatives derivative NNS cord-277665-ac8txr3h 25 11 of of IN cord-277665-ac8txr3h 25 12 organic organic JJ cord-277665-ac8txr3h 25 13 and and CC cord-277665-ac8txr3h 25 14 inorganic inorganic JJ cord-277665-ac8txr3h 25 15 molecular molecular JJ cord-277665-ac8txr3h 25 16 entities entity NNS cord-277665-ac8txr3h 25 17 began begin VBD cord-277665-ac8txr3h 25 18 to to TO cord-277665-ac8txr3h 25 19 play play VB cord-277665-ac8txr3h 25 20 increasingly increasingly RB cord-277665-ac8txr3h 25 21 important important JJ cord-277665-ac8txr3h 25 22 roles role NNS cord-277665-ac8txr3h 25 23 in in IN cord-277665-ac8txr3h 25 24 a a DT cord-277665-ac8txr3h 25 25 variety variety NN cord-277665-ac8txr3h 25 26 of of IN cord-277665-ac8txr3h 25 27 applications application NNS cord-277665-ac8txr3h 25 28 in in IN cord-277665-ac8txr3h 25 29 nanobiotechnology nanobiotechnology NNP cord-277665-ac8txr3h 25 30 ( ( -LRB- cord-277665-ac8txr3h 25 31 Niemeyer Niemeyer NNP cord-277665-ac8txr3h 25 32 , , , cord-277665-ac8txr3h 25 33 2001 2001 CD cord-277665-ac8txr3h 25 34 ) ) -RRB- cord-277665-ac8txr3h 25 35 , , , cord-277665-ac8txr3h 25 36 genomics genomic NNS cord-277665-ac8txr3h 25 37 ( ( -LRB- cord-277665-ac8txr3h 25 38 Wengel Wengel NNP cord-277665-ac8txr3h 25 39 , , , cord-277665-ac8txr3h 25 40 2004 2004 CD cord-277665-ac8txr3h 25 41 ) ) -RRB- cord-277665-ac8txr3h 25 42 , , , cord-277665-ac8txr3h 25 43 drug drug NN cord-277665-ac8txr3h 25 44 discovery discovery NN cord-277665-ac8txr3h 25 45 ( ( -LRB- cord-277665-ac8txr3h 25 46 Ozkan Ozkan NNP cord-277665-ac8txr3h 25 47 , , , cord-277665-ac8txr3h 25 48 2004 2004 CD cord-277665-ac8txr3h 25 49 ) ) -RRB- cord-277665-ac8txr3h 25 50 , , , cord-277665-ac8txr3h 25 51 and and CC cord-277665-ac8txr3h 25 52 nanomedicine nanomedicine NN cord-277665-ac8txr3h 25 53 ( ( -LRB- cord-277665-ac8txr3h 25 54 Freitas Freitas NNP cord-277665-ac8txr3h 25 55 , , , cord-277665-ac8txr3h 25 56 2003 2003 CD cord-277665-ac8txr3h 25 57 ) ) -RRB- cord-277665-ac8txr3h 25 58 . . . cord-277665-ac8txr3h 26 1 For for IN cord-277665-ac8txr3h 26 2 example example NN cord-277665-ac8txr3h 26 3 , , , cord-277665-ac8txr3h 26 4 zero zero CD cord-277665-ac8txr3h 26 5 - - HYPH cord-277665-ac8txr3h 26 6 dimensional dimensional JJ cord-277665-ac8txr3h 26 7 nanostructures nanostructure NNS cord-277665-ac8txr3h 26 8 reported report VBN cord-277665-ac8txr3h 26 9 for for IN cord-277665-ac8txr3h 26 10 medical medical JJ cord-277665-ac8txr3h 26 11 applications application NNS cord-277665-ac8txr3h 26 12 include include VBP cord-277665-ac8txr3h 26 13 gold gold NN cord-277665-ac8txr3h 26 14 and and CC cord-277665-ac8txr3h 26 15 magnetic magnetic JJ cord-277665-ac8txr3h 26 16 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 26 17 , , , cord-277665-ac8txr3h 26 18 semiconductor semiconductor NN cord-277665-ac8txr3h 26 19 quantum quantum NN cord-277665-ac8txr3h 26 20 dots dot NNS cord-277665-ac8txr3h 26 21 , , , cord-277665-ac8txr3h 26 22 a a DT cord-277665-ac8txr3h 26 23 wide wide JJ cord-277665-ac8txr3h 26 24 variety variety NN cord-277665-ac8txr3h 26 25 of of IN cord-277665-ac8txr3h 26 26 polymer polymer NN cord-277665-ac8txr3h 26 27 - - HYPH cord-277665-ac8txr3h 26 28 based base VBN cord-277665-ac8txr3h 26 29 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 26 30 , , , cord-277665-ac8txr3h 26 31 nanoshells nanoshell NNS cord-277665-ac8txr3h 26 32 consisting consist VBG cord-277665-ac8txr3h 26 33 of of IN cord-277665-ac8txr3h 26 34 metals metal NNS cord-277665-ac8txr3h 26 35 and and CC cord-277665-ac8txr3h 26 36 dielectrics dielectric NNS cord-277665-ac8txr3h 26 37 , , , cord-277665-ac8txr3h 26 38 and and CC cord-277665-ac8txr3h 26 39 many many JJ cord-277665-ac8txr3h 26 40 others other NNS cord-277665-ac8txr3h 26 41 . . . cord-277665-ac8txr3h 27 1 Nanoparticles nanoparticle NNS cord-277665-ac8txr3h 27 2 act act VBP cord-277665-ac8txr3h 27 3 as as IN cord-277665-ac8txr3h 27 4 potential potential JJ cord-277665-ac8txr3h 27 5 carries carry VBZ cord-277665-ac8txr3h 27 6 for for IN cord-277665-ac8txr3h 27 7 several several JJ cord-277665-ac8txr3h 27 8 classes class NNS cord-277665-ac8txr3h 27 9 of of IN cord-277665-ac8txr3h 27 10 drugs drug NNS cord-277665-ac8txr3h 27 11 such such JJ cord-277665-ac8txr3h 27 12 as as IN cord-277665-ac8txr3h 27 13 anticancer anticancer JJ cord-277665-ac8txr3h 27 14 agents agent NNS cord-277665-ac8txr3h 27 15 , , , cord-277665-ac8txr3h 27 16 antihypertensive antihypertensive JJ cord-277665-ac8txr3h 27 17 agents agent NNS cord-277665-ac8txr3h 27 18 , , , cord-277665-ac8txr3h 27 19 immunomodulators immunomodulator NNS cord-277665-ac8txr3h 27 20 , , , cord-277665-ac8txr3h 27 21 and and CC cord-277665-ac8txr3h 27 22 hormones hormone NNS cord-277665-ac8txr3h 27 23 ; ; : cord-277665-ac8txr3h 27 24 and and CC cord-277665-ac8txr3h 27 25 macromolecules macromolecule NNS cord-277665-ac8txr3h 27 26 such such JJ cord-277665-ac8txr3h 27 27 as as IN cord-277665-ac8txr3h 27 28 nucleic nucleic JJ cord-277665-ac8txr3h 27 29 acids acid NNS cord-277665-ac8txr3h 27 30 , , , cord-277665-ac8txr3h 27 31 proteins protein NNS cord-277665-ac8txr3h 27 32 , , , cord-277665-ac8txr3h 27 33 peptides peptide NNS cord-277665-ac8txr3h 27 34 , , , cord-277665-ac8txr3h 27 35 and and CC cord-277665-ac8txr3h 27 36 antibodies antibody NNS cord-277665-ac8txr3h 27 37 . . . cord-277665-ac8txr3h 28 1 An an DT cord-277665-ac8txr3h 28 2 absence absence NN cord-277665-ac8txr3h 28 3 of of IN cord-277665-ac8txr3h 28 4 narrow narrow JJ cord-277665-ac8txr3h 28 5 fractions fraction NNS cord-277665-ac8txr3h 28 6 of of IN cord-277665-ac8txr3h 28 7 nanodiamond nanodiamond NN cord-277665-ac8txr3h 28 8 particulate particulate NN cord-277665-ac8txr3h 28 9 on on IN cord-277665-ac8txr3h 28 10 the the DT cord-277665-ac8txr3h 28 11 market market NN cord-277665-ac8txr3h 28 12 hindered hinder VBD cord-277665-ac8txr3h 28 13 their -PRON- PRP$ cord-277665-ac8txr3h 28 14 biomedical biomedical JJ cord-277665-ac8txr3h 28 15 applications application NNS cord-277665-ac8txr3h 28 16 . . . cord-277665-ac8txr3h 29 1 Recently recently RB cord-277665-ac8txr3h 29 2 , , , cord-277665-ac8txr3h 29 3 however however RB cord-277665-ac8txr3h 29 4 , , , cord-277665-ac8txr3h 29 5 production production NN cord-277665-ac8txr3h 29 6 of of IN cord-277665-ac8txr3h 29 7 narrow narrow JJ cord-277665-ac8txr3h 29 8 fractions fraction NNS cord-277665-ac8txr3h 29 9 of of IN cord-277665-ac8txr3h 29 10 ND ND NNP cord-277665-ac8txr3h 29 11 ( ( -LRB- cord-277665-ac8txr3h 29 12 5 5 CD cord-277665-ac8txr3h 29 13 nm nm NN cord-277665-ac8txr3h 29 14 sized sized JJ cord-277665-ac8txr3h 29 15 particle particle NN cord-277665-ac8txr3h 29 16 suspensions suspension NNS cord-277665-ac8txr3h 29 17 ; ; : cord-277665-ac8txr3h 29 18 several several JJ cord-277665-ac8txr3h 29 19 fractions fraction NNS cord-277665-ac8txr3h 29 20 within within IN cord-277665-ac8txr3h 29 21 the the DT cord-277665-ac8txr3h 29 22 40 40 CD cord-277665-ac8txr3h 29 23 - - SYM cord-277665-ac8txr3h 29 24 100 100 CD cord-277665-ac8txr3h 29 25 nm nm NN cord-277665-ac8txr3h 29 26 size size NN cord-277665-ac8txr3h 29 27 range range NN cord-277665-ac8txr3h 29 28 as as RB cord-277665-ac8txr3h 29 29 well well RB cord-277665-ac8txr3h 29 30 as as IN cord-277665-ac8txr3h 29 31 fractions fraction NNS cord-277665-ac8txr3h 29 32 above above IN cord-277665-ac8txr3h 29 33 100 100 CD cord-277665-ac8txr3h 29 34 nm nm NN cord-277665-ac8txr3h 29 35 ) ) -RRB- cord-277665-ac8txr3h 29 36 has have VBZ cord-277665-ac8txr3h 29 37 been be VBN cord-277665-ac8txr3h 29 38 achieved achieve VBN cord-277665-ac8txr3h 29 39 in in IN cord-277665-ac8txr3h 29 40 research research NN cord-277665-ac8txr3h 29 41 laboratories laboratory NNS cord-277665-ac8txr3h 29 42 ( ( -LRB- cord-277665-ac8txr3h 29 43 Chapter chapter NN cord-277665-ac8txr3h 29 44 3 3 CD cord-277665-ac8txr3h 29 45 of of IN cord-277665-ac8txr3h 29 46 this this DT cord-277665-ac8txr3h 29 47 book book NN cord-277665-ac8txr3h 29 48 and and CC cord-277665-ac8txr3h 29 49 private private JJ cord-277665-ac8txr3h 29 50 communications communication NNS cord-277665-ac8txr3h 29 51 ) ) -RRB- cord-277665-ac8txr3h 29 52 . . . cord-277665-ac8txr3h 30 1 In in IN cord-277665-ac8txr3h 30 2 combination combination NN cord-277665-ac8txr3h 30 3 with with IN cord-277665-ac8txr3h 30 4 the the DT cord-277665-ac8txr3h 30 5 advances advance NNS cord-277665-ac8txr3h 30 6 in in IN cord-277665-ac8txr3h 30 7 the the DT cord-277665-ac8txr3h 30 8 production production NN cord-277665-ac8txr3h 30 9 of of IN cord-277665-ac8txr3h 30 10 high high JJ cord-277665-ac8txr3h 30 11 - - HYPH cord-277665-ac8txr3h 30 12 purity purity NN cord-277665-ac8txr3h 30 13 particles particle NNS cord-277665-ac8txr3h 30 14 and and CC cord-277665-ac8txr3h 30 15 the the DT cord-277665-ac8txr3h 30 16 fact fact NN cord-277665-ac8txr3h 30 17 that that IN cord-277665-ac8txr3h 30 18 UNCD UNCD NNP cord-277665-ac8txr3h 30 19 particles particle NNS cord-277665-ac8txr3h 30 20 of of IN cord-277665-ac8txr3h 30 21 detonation detonation NN cord-277665-ac8txr3h 30 22 origin origin NN cord-277665-ac8txr3h 30 23 are be VBP cord-277665-ac8txr3h 30 24 relatively relatively RB cord-277665-ac8txr3h 30 25 inexpensive inexpensive JJ cord-277665-ac8txr3h 30 26 ( ( -LRB- cord-277665-ac8txr3h 30 27 compared compare VBN cord-277665-ac8txr3h 30 28 to to IN cord-277665-ac8txr3h 30 29 fullerenes fullerene NNS cord-277665-ac8txr3h 30 30 , , , cord-277665-ac8txr3h 30 31 pure pure JJ cord-277665-ac8txr3h 30 32 carbon carbon NN cord-277665-ac8txr3h 30 33 nanotube nanotube NN cord-277665-ac8txr3h 30 34 ( ( -LRB- cord-277665-ac8txr3h 30 35 CNT CNT NNP cord-277665-ac8txr3h 30 36 ) ) -RRB- cord-277665-ac8txr3h 30 37 , , , cord-277665-ac8txr3h 30 38 and and CC cord-277665-ac8txr3h 30 39 gold gold NN cord-277665-ac8txr3h 30 40 particles particle NNS cord-277665-ac8txr3h 30 41 , , , cord-277665-ac8txr3h 30 42 for for IN cord-277665-ac8txr3h 30 43 example example NN cord-277665-ac8txr3h 30 44 ) ) -RRB- cord-277665-ac8txr3h 30 45 , , , cord-277665-ac8txr3h 30 46 a a DT cord-277665-ac8txr3h 30 47 fast fast JJ cord-277665-ac8txr3h 30 48 growth growth NN cord-277665-ac8txr3h 30 49 of of IN cord-277665-ac8txr3h 30 50 bioapplications bioapplication NNS cord-277665-ac8txr3h 30 51 of of IN cord-277665-ac8txr3h 30 52 ND ND NNP cord-277665-ac8txr3h 30 53 particulate particulate NN cord-277665-ac8txr3h 30 54 is be VBZ cord-277665-ac8txr3h 30 55 expected expect VBN cord-277665-ac8txr3h 30 56 . . . cord-277665-ac8txr3h 31 1 This this DT cord-277665-ac8txr3h 31 2 chapter chapter NN cord-277665-ac8txr3h 31 3 will will MD cord-277665-ac8txr3h 31 4 be be VB cord-277665-ac8txr3h 31 5 organized organize VBN cord-277665-ac8txr3h 31 6 as as IN cord-277665-ac8txr3h 31 7 follows follow VBZ cord-277665-ac8txr3h 31 8 : : : cord-277665-ac8txr3h 31 9 in in IN cord-277665-ac8txr3h 31 10 the the DT cord-277665-ac8txr3h 31 11 next next JJ cord-277665-ac8txr3h 31 12 section section NN cord-277665-ac8txr3h 31 13 different different JJ cord-277665-ac8txr3h 31 14 approaches approach NNS cord-277665-ac8txr3h 31 15 to to IN cord-277665-ac8txr3h 31 16 the the DT cord-277665-ac8txr3h 31 17 surface surface NN cord-277665-ac8txr3h 31 18 functionalization functionalization NN cord-277665-ac8txr3h 31 19 of of IN cord-277665-ac8txr3h 31 20 ND ND NNP cord-277665-ac8txr3h 31 21 particles particle NNS cord-277665-ac8txr3h 31 22 , , , cord-277665-ac8txr3h 31 23 that that RB cord-277665-ac8txr3h 31 24 is is RB cord-277665-ac8txr3h 31 25 , , , cord-277665-ac8txr3h 31 26 the the DT cord-277665-ac8txr3h 31 27 key key NN cord-277665-ac8txr3h 31 28 in in IN cord-277665-ac8txr3h 31 29 successful successful JJ cord-277665-ac8txr3h 31 30 biomedical biomedical JJ cord-277665-ac8txr3h 31 31 applications application NNS cord-277665-ac8txr3h 31 32 , , , cord-277665-ac8txr3h 31 33 will will MD cord-277665-ac8txr3h 31 34 be be VB cord-277665-ac8txr3h 31 35 summarized summarize VBN cord-277665-ac8txr3h 31 36 , , , cord-277665-ac8txr3h 31 37 followed follow VBN cord-277665-ac8txr3h 31 38 by by IN cord-277665-ac8txr3h 31 39 a a DT cord-277665-ac8txr3h 31 40 discussion discussion NN cord-277665-ac8txr3h 31 41 of of IN cord-277665-ac8txr3h 31 42 modification modification NN cord-277665-ac8txr3h 31 43 of of IN cord-277665-ac8txr3h 31 44 diamond diamond NN cord-277665-ac8txr3h 31 45 surfaces surface NNS cord-277665-ac8txr3h 31 46 with with IN cord-277665-ac8txr3h 31 47 nucleic nucleic JJ cord-277665-ac8txr3h 31 48 acids acid NNS cord-277665-ac8txr3h 31 49 and and CC cord-277665-ac8txr3h 31 50 proteins protein NNS cord-277665-ac8txr3h 31 51 . . . cord-277665-ac8txr3h 32 1 After after IN cord-277665-ac8txr3h 32 2 that that DT cord-277665-ac8txr3h 32 3 both both CC cord-277665-ac8txr3h 32 4 current current JJ cord-277665-ac8txr3h 32 5 and and CC cord-277665-ac8txr3h 32 6 potential potential JJ cord-277665-ac8txr3h 32 7 applications application NNS cord-277665-ac8txr3h 32 8 of of IN cord-277665-ac8txr3h 32 9 diamond diamond NN cord-277665-ac8txr3h 32 10 films film NNS cord-277665-ac8txr3h 32 11 and and CC cord-277665-ac8txr3h 32 12 particles particle NNS cord-277665-ac8txr3h 32 13 in in IN cord-277665-ac8txr3h 32 14 the the DT cord-277665-ac8txr3h 32 15 areas area NNS cord-277665-ac8txr3h 32 16 of of IN cord-277665-ac8txr3h 32 17 biosensing biosensing NN cord-277665-ac8txr3h 32 18 and and CC cord-277665-ac8txr3h 32 19 medicine medicine NN cord-277665-ac8txr3h 32 20 will will MD cord-277665-ac8txr3h 32 21 be be VB cord-277665-ac8txr3h 32 22 addressed address VBN cord-277665-ac8txr3h 32 23 . . . cord-277665-ac8txr3h 33 1 The the DT cord-277665-ac8txr3h 33 2 concluding conclude VBG cord-277665-ac8txr3h 33 3 section section NN cord-277665-ac8txr3h 33 4 will will MD cord-277665-ac8txr3h 33 5 summarize summarize VB cord-277665-ac8txr3h 33 6 results result NNS cord-277665-ac8txr3h 33 7 reported report VBN cord-277665-ac8txr3h 33 8 on on IN cord-277665-ac8txr3h 33 9 the the DT cord-277665-ac8txr3h 33 10 biocompatibility biocompatibility NN cord-277665-ac8txr3h 33 11 of of IN cord-277665-ac8txr3h 33 12 ND ND NNP cord-277665-ac8txr3h 33 13 , , , cord-277665-ac8txr3h 33 14 the the DT cord-277665-ac8txr3h 33 15 paramount paramount JJ cord-277665-ac8txr3h 33 16 property property NN cord-277665-ac8txr3h 33 17 in in IN cord-277665-ac8txr3h 33 18 the the DT cord-277665-ac8txr3h 33 19 biomedical biomedical JJ cord-277665-ac8txr3h 33 20 applications application NNS cord-277665-ac8txr3h 33 21 of of IN cord-277665-ac8txr3h 33 22 artificial artificial JJ cord-277665-ac8txr3h 33 23 nanostructures nanostructure NNS cord-277665-ac8txr3h 33 24 . . . cord-277665-ac8txr3h 34 1 Diamond Diamond NNP cord-277665-ac8txr3h 34 2 possesses possess VBZ cord-277665-ac8txr3h 34 3 a a DT cord-277665-ac8txr3h 34 4 number number NN cord-277665-ac8txr3h 34 5 of of IN cord-277665-ac8txr3h 34 6 distinct distinct JJ cord-277665-ac8txr3h 34 7 properties property NNS cord-277665-ac8txr3h 34 8 that that WDT cord-277665-ac8txr3h 34 9 make make VBP cord-277665-ac8txr3h 34 10 it -PRON- PRP cord-277665-ac8txr3h 34 11 an an DT cord-277665-ac8txr3h 34 12 attractive attractive JJ cord-277665-ac8txr3h 34 13 biotechnological biotechnological JJ cord-277665-ac8txr3h 34 14 material material NN cord-277665-ac8txr3h 34 15 . . . cord-277665-ac8txr3h 35 1 Although although IN cord-277665-ac8txr3h 35 2 natural natural JJ cord-277665-ac8txr3h 35 3 diamond diamond NN cord-277665-ac8txr3h 35 4 is be VBZ cord-277665-ac8txr3h 35 5 highly highly RB cord-277665-ac8txr3h 35 6 hydrophobic hydrophobic JJ cord-277665-ac8txr3h 35 7 , , , cord-277665-ac8txr3h 35 8 hydrophilic hydrophilic JJ cord-277665-ac8txr3h 35 9 surface surface NN cord-277665-ac8txr3h 35 10 groups group NNS cord-277665-ac8txr3h 35 11 , , , cord-277665-ac8txr3h 35 12 important important JJ cord-277665-ac8txr3h 35 13 for for IN cord-277665-ac8txr3h 35 14 bioapplications bioapplication NNS cord-277665-ac8txr3h 35 15 , , , cord-277665-ac8txr3h 35 16 can can MD cord-277665-ac8txr3h 35 17 be be VB cord-277665-ac8txr3h 35 18 generated generate VBN cord-277665-ac8txr3h 35 19 on on IN cord-277665-ac8txr3h 35 20 a a DT cord-277665-ac8txr3h 35 21 diamond diamond NN cord-277665-ac8txr3h 35 22 surface surface NN cord-277665-ac8txr3h 35 23 by by IN cord-277665-ac8txr3h 35 24 heating heat VBG cord-277665-ac8txr3h 35 25 to to IN cord-277665-ac8txr3h 35 26 high high JJ cord-277665-ac8txr3h 35 27 temperature temperature NN cord-277665-ac8txr3h 35 28 in in IN cord-277665-ac8txr3h 35 29 an an DT cord-277665-ac8txr3h 35 30 oxygen oxygen NN cord-277665-ac8txr3h 35 31 atmosphere atmosphere NN cord-277665-ac8txr3h 35 32 and and CC cord-277665-ac8txr3h 35 33 using use VBG cord-277665-ac8txr3h 35 34 ion ion NN cord-277665-ac8txr3h 35 35 bombardment bombardment NN cord-277665-ac8txr3h 35 36 and and CC cord-277665-ac8txr3h 35 37 other other JJ cord-277665-ac8txr3h 35 38 rather rather RB cord-277665-ac8txr3h 35 39 aggressive aggressive JJ cord-277665-ac8txr3h 35 40 treatments treatment NNS cord-277665-ac8txr3h 35 41 . . . cord-277665-ac8txr3h 36 1 ND ND NNP cord-277665-ac8txr3h 36 2 particles particle NNS cord-277665-ac8txr3h 36 3 synthesized synthesize VBN cord-277665-ac8txr3h 36 4 by by IN cord-277665-ac8txr3h 36 5 detonation detonation NN cord-277665-ac8txr3h 36 6 have have VBP cord-277665-ac8txr3h 36 7 numerous numerous JJ cord-277665-ac8txr3h 36 8 oxygen oxygen NN cord-277665-ac8txr3h 36 9 - - HYPH cord-277665-ac8txr3h 36 10 containing contain VBG cord-277665-ac8txr3h 36 11 chemical chemical JJ cord-277665-ac8txr3h 36 12 groups group NNS cord-277665-ac8txr3h 36 13 on on IN cord-277665-ac8txr3h 36 14 the the DT cord-277665-ac8txr3h 36 15 surface surface NN cord-277665-ac8txr3h 36 16 and and CC cord-277665-ac8txr3h 36 17 , , , cord-277665-ac8txr3h 36 18 thus thus RB cord-277665-ac8txr3h 36 19 , , , cord-277665-ac8txr3h 36 20 are be VBP cord-277665-ac8txr3h 36 21 intrinsically intrinsically RB cord-277665-ac8txr3h 36 22 hydrophilic hydrophilic JJ cord-277665-ac8txr3h 36 23 . . . cord-277665-ac8txr3h 37 1 The the DT cord-277665-ac8txr3h 37 2 detonation detonation NN cord-277665-ac8txr3h 37 3 ND ND NNP cord-277665-ac8txr3h 37 4 particles particle NNS cord-277665-ac8txr3h 37 5 are be VBP cord-277665-ac8txr3h 37 6 4 4 CD cord-277665-ac8txr3h 37 7 - - SYM cord-277665-ac8txr3h 37 8 5 5 CD cord-277665-ac8txr3h 37 9 nm nm CD cord-277665-ac8txr3h 37 10 round round RB cord-277665-ac8txr3h 37 11 - - HYPH cord-277665-ac8txr3h 37 12 shaped shape VBN cord-277665-ac8txr3h 37 13 monocrystals monocrystal NNS cord-277665-ac8txr3h 37 14 that that WDT cord-277665-ac8txr3h 37 15 form form VBP cord-277665-ac8txr3h 37 16 tightly tightly RB cord-277665-ac8txr3h 37 17 and and CC cord-277665-ac8txr3h 37 18 loosely loosely RB cord-277665-ac8txr3h 37 19 bond bond NN cord-277665-ac8txr3h 37 20 aggregates aggregate NNS cord-277665-ac8txr3h 37 21 of of IN cord-277665-ac8txr3h 37 22 about about RB cord-277665-ac8txr3h 37 23 50 50 CD cord-277665-ac8txr3h 37 24 nm nm NN cord-277665-ac8txr3h 37 25 and and CC cord-277665-ac8txr3h 38 1 100 100 CD cord-277665-ac8txr3h 38 2 - - SYM cord-277665-ac8txr3h 38 3 200 200 CD cord-277665-ac8txr3h 38 4 nm nm NN cord-277665-ac8txr3h 38 5 in in IN cord-277665-ac8txr3h 38 6 diameter diameter NN cord-277665-ac8txr3h 38 7 , , , cord-277665-ac8txr3h 38 8 correspondingly correspondingly RB cord-277665-ac8txr3h 38 9 . . . cord-277665-ac8txr3h 39 1 Detonation detonation NN cord-277665-ac8txr3h 39 2 ND ND NNP cord-277665-ac8txr3h 39 3 possesses possess VBZ cord-277665-ac8txr3h 39 4 a a DT cord-277665-ac8txr3h 39 5 very very RB cord-277665-ac8txr3h 39 6 large large JJ cord-277665-ac8txr3h 39 7 specific specific JJ cord-277665-ac8txr3h 39 8 surface surface NN cord-277665-ac8txr3h 39 9 area area NN cord-277665-ac8txr3h 39 10 ( ( -LRB- cord-277665-ac8txr3h 39 11 300 300 CD cord-277665-ac8txr3h 39 12 - - SYM cord-277665-ac8txr3h 39 13 400 400 CD cord-277665-ac8txr3h 39 14 m m CD cord-277665-ac8txr3h 39 15 2 2 CD cord-277665-ac8txr3h 39 16 g g NN cord-277665-ac8txr3h 39 17 −1 −1 NNP cord-277665-ac8txr3h 39 18 ) ) -RRB- cord-277665-ac8txr3h 40 1 ( ( -LRB- cord-277665-ac8txr3h 40 2 Dolmatov Dolmatov NNP cord-277665-ac8txr3h 40 3 , , , cord-277665-ac8txr3h 40 4 2001 2001 CD cord-277665-ac8txr3h 40 5 ) ) -RRB- cord-277665-ac8txr3h 40 6 , , , cord-277665-ac8txr3h 40 7 which which WDT cord-277665-ac8txr3h 40 8 is be VBZ cord-277665-ac8txr3h 40 9 an an DT cord-277665-ac8txr3h 40 10 important important JJ cord-277665-ac8txr3h 40 11 factor factor NN cord-277665-ac8txr3h 40 12 for for IN cord-277665-ac8txr3h 40 13 bioapplications bioapplication NNS cord-277665-ac8txr3h 40 14 . . . cord-277665-ac8txr3h 41 1 Detonation detonation NN cord-277665-ac8txr3h 41 2 ND ND NNP cord-277665-ac8txr3h 41 3 is be VBZ cord-277665-ac8txr3h 41 4 likely likely JJ cord-277665-ac8txr3h 41 5 to to TO cord-277665-ac8txr3h 41 6 have have VB cord-277665-ac8txr3h 41 7 a a DT cord-277665-ac8txr3h 41 8 significant significant JJ cord-277665-ac8txr3h 41 9 number number NN cord-277665-ac8txr3h 41 10 of of IN cord-277665-ac8txr3h 41 11 unpaired unpaired JJ cord-277665-ac8txr3h 41 12 electrons electron NNS cord-277665-ac8txr3h 41 13 that that WDT cord-277665-ac8txr3h 41 14 make make VBP cord-277665-ac8txr3h 41 15 it -PRON- PRP cord-277665-ac8txr3h 41 16 an an DT cord-277665-ac8txr3h 41 17 efficient efficient JJ cord-277665-ac8txr3h 41 18 free free JJ cord-277665-ac8txr3h 41 19 radical radical JJ cord-277665-ac8txr3h 41 20 scavenger scavenger NN cord-277665-ac8txr3h 41 21 and and CC cord-277665-ac8txr3h 41 22 opens open VBZ cord-277665-ac8txr3h 41 23 up up RP cord-277665-ac8txr3h 41 24 the the DT cord-277665-ac8txr3h 41 25 opportunity opportunity NN cord-277665-ac8txr3h 41 26 for for IN cord-277665-ac8txr3h 41 27 its -PRON- PRP$ cord-277665-ac8txr3h 41 28 use use NN cord-277665-ac8txr3h 41 29 in in IN cord-277665-ac8txr3h 41 30 medicine medicine NN cord-277665-ac8txr3h 41 31 ( ( -LRB- cord-277665-ac8txr3h 41 32 Kulakova Kulakova NNP cord-277665-ac8txr3h 41 33 et et NNP cord-277665-ac8txr3h 41 34 al al NNP cord-277665-ac8txr3h 41 35 . . NNP cord-277665-ac8txr3h 41 36 , , , cord-277665-ac8txr3h 41 37 2000 2000 CD cord-277665-ac8txr3h 41 38 ; ; : cord-277665-ac8txr3h 41 39 Nachalnaya Nachalnaya NNP cord-277665-ac8txr3h 41 40 et et NNP cord-277665-ac8txr3h 41 41 al al NNP cord-277665-ac8txr3h 41 42 . . NNP cord-277665-ac8txr3h 41 43 , , , cord-277665-ac8txr3h 41 44 2000 2000 CD cord-277665-ac8txr3h 41 45 ) ) -RRB- cord-277665-ac8txr3h 41 46 . . . cord-277665-ac8txr3h 42 1 In in IN cord-277665-ac8txr3h 42 2 general general JJ cord-277665-ac8txr3h 42 3 , , , cord-277665-ac8txr3h 42 4 the the DT cord-277665-ac8txr3h 42 5 size size NN cord-277665-ac8txr3h 42 6 , , , cord-277665-ac8txr3h 42 7 purity purity NN cord-277665-ac8txr3h 42 8 , , , cord-277665-ac8txr3h 42 9 and and CC cord-277665-ac8txr3h 42 10 surface surface NN cord-277665-ac8txr3h 42 11 chemistry chemistry NN cord-277665-ac8txr3h 42 12 of of IN cord-277665-ac8txr3h 42 13 detonation detonation NN cord-277665-ac8txr3h 42 14 ND ND NNP cord-277665-ac8txr3h 42 15 varies vary VBZ cord-277665-ac8txr3h 42 16 considerably considerably RB cord-277665-ac8txr3h 42 17 from from IN cord-277665-ac8txr3h 42 18 one one CD cord-277665-ac8txr3h 42 19 manufacturer manufacturer NN cord-277665-ac8txr3h 42 20 to to IN cord-277665-ac8txr3h 42 21 another another DT cord-277665-ac8txr3h 42 22 . . . cord-277665-ac8txr3h 43 1 The the DT cord-277665-ac8txr3h 43 2 composition composition NN cord-277665-ac8txr3h 43 3 of of IN cord-277665-ac8txr3h 43 4 the the DT cord-277665-ac8txr3h 43 5 explosive explosive JJ cord-277665-ac8txr3h 43 6 mixture mixture NN cord-277665-ac8txr3h 43 7 , , , cord-277665-ac8txr3h 43 8 coolant coolant NN cord-277665-ac8txr3h 43 9 media medium NNS cord-277665-ac8txr3h 43 10 , , , cord-277665-ac8txr3h 43 11 chamber chamber NN cord-277665-ac8txr3h 43 12 size size NN cord-277665-ac8txr3h 43 13 , , , cord-277665-ac8txr3h 43 14 and and CC cord-277665-ac8txr3h 43 15 consequent consequent JJ cord-277665-ac8txr3h 43 16 purification purification NN cord-277665-ac8txr3h 43 17 of of IN cord-277665-ac8txr3h 43 18 detonation detonation NN cord-277665-ac8txr3h 43 19 soot soot NN cord-277665-ac8txr3h 43 20 are be VBP cord-277665-ac8txr3h 43 21 all all DT cord-277665-ac8txr3h 43 22 important important JJ cord-277665-ac8txr3h 43 23 factors factor NNS cord-277665-ac8txr3h 43 24 in in IN cord-277665-ac8txr3h 43 25 the the DT cord-277665-ac8txr3h 43 26 manufacture manufacture NN cord-277665-ac8txr3h 43 27 of of IN cord-277665-ac8txr3h 43 28 UNCD UNCD NNP cord-277665-ac8txr3h 43 29 particles particle NNS cord-277665-ac8txr3h 43 30 with with IN cord-277665-ac8txr3h 43 31 the the DT cord-277665-ac8txr3h 43 32 desirable desirable JJ cord-277665-ac8txr3h 43 33 physical physical JJ cord-277665-ac8txr3h 43 34 and and CC cord-277665-ac8txr3h 43 35 chemical chemical JJ cord-277665-ac8txr3h 43 36 properties property NNS cord-277665-ac8txr3h 43 37 of of IN cord-277665-ac8txr3h 43 38 their -PRON- PRP$ cord-277665-ac8txr3h 43 39 surface surface NN cord-277665-ac8txr3h 43 40 ( ( -LRB- cord-277665-ac8txr3h 43 41 Donnet Donnet NNP cord-277665-ac8txr3h 43 42 et et NNP cord-277665-ac8txr3h 43 43 al al NNP cord-277665-ac8txr3h 43 44 . . NNP cord-277665-ac8txr3h 43 45 , , , cord-277665-ac8txr3h 43 46 1997 1997 CD cord-277665-ac8txr3h 43 47 ) ) -RRB- cord-277665-ac8txr3h 43 48 . . . cord-277665-ac8txr3h 44 1 The the DT cord-277665-ac8txr3h 44 2 methods method NNS cord-277665-ac8txr3h 44 3 of of IN cord-277665-ac8txr3h 44 4 extraction extraction NN cord-277665-ac8txr3h 44 5 and and CC cord-277665-ac8txr3h 44 6 purification purification NN cord-277665-ac8txr3h 44 7 of of IN cord-277665-ac8txr3h 44 8 ND ND NNP cord-277665-ac8txr3h 44 9 from from IN cord-277665-ac8txr3h 44 10 the the DT cord-277665-ac8txr3h 44 11 detonation detonation NN cord-277665-ac8txr3h 44 12 product product NN cord-277665-ac8txr3h 44 13 may may MD cord-277665-ac8txr3h 44 14 include include VB cord-277665-ac8txr3h 44 15 ozone ozone NN cord-277665-ac8txr3h 44 16 treatment treatment NN cord-277665-ac8txr3h 44 17 , , , cord-277665-ac8txr3h 44 18 oxidation oxidation NN cord-277665-ac8txr3h 44 19 by by IN cord-277665-ac8txr3h 44 20 different different JJ cord-277665-ac8txr3h 44 21 reagents reagent NNS cord-277665-ac8txr3h 44 22 with with IN cord-277665-ac8txr3h 44 23 / / SYM cord-277665-ac8txr3h 44 24 without without IN cord-277665-ac8txr3h 44 25 catalysts catalyst NNS cord-277665-ac8txr3h 44 26 , , , cord-277665-ac8txr3h 44 27 treatment treatment NN cord-277665-ac8txr3h 44 28 with with IN cord-277665-ac8txr3h 44 29 acids acid NNS cord-277665-ac8txr3h 44 30 , , , cord-277665-ac8txr3h 44 31 modification modification NN cord-277665-ac8txr3h 44 32 of of IN cord-277665-ac8txr3h 44 33 the the DT cord-277665-ac8txr3h 44 34 ND ND NNP cord-277665-ac8txr3h 44 35 surface surface NN cord-277665-ac8txr3h 44 36 in in IN cord-277665-ac8txr3h 44 37 gaseous gaseous JJ cord-277665-ac8txr3h 44 38 and and CC cord-277665-ac8txr3h 44 39 liquid liquid JJ cord-277665-ac8txr3h 44 40 media medium NNS cord-277665-ac8txr3h 44 41 ( ( -LRB- cord-277665-ac8txr3h 44 42 Kulakova Kulakova NNP cord-277665-ac8txr3h 44 43 , , , cord-277665-ac8txr3h 44 44 2004 2004 CD cord-277665-ac8txr3h 44 45 ) ) -RRB- cord-277665-ac8txr3h 44 46 , , , cord-277665-ac8txr3h 44 47 selective selective JJ cord-277665-ac8txr3h 44 48 inhibition inhibition NN cord-277665-ac8txr3h 44 49 of of IN cord-277665-ac8txr3h 44 50 ND ND NNP cord-277665-ac8txr3h 44 51 oxidation oxidation NN cord-277665-ac8txr3h 44 52 ( ( -LRB- cord-277665-ac8txr3h 44 53 Chiganov Chiganov NNP cord-277665-ac8txr3h 44 54 , , , cord-277665-ac8txr3h 44 55 2004 2004 CD cord-277665-ac8txr3h 44 56 ) ) -RRB- cord-277665-ac8txr3h 44 57 , , , cord-277665-ac8txr3h 44 58 and and CC cord-277665-ac8txr3h 44 59 many many JJ cord-277665-ac8txr3h 44 60 others other NNS cord-277665-ac8txr3h 44 61 . . . cord-277665-ac8txr3h 45 1 Disaggregating disaggregating NN cord-277665-ac8txr3h 45 2 of of IN cord-277665-ac8txr3h 45 3 detonation detonation NN cord-277665-ac8txr3h 45 4 ND ND NNP cord-277665-ac8txr3h 45 5 can can MD cord-277665-ac8txr3h 45 6 be be VB cord-277665-ac8txr3h 45 7 achieved achieve VBN cord-277665-ac8txr3h 45 8 , , , cord-277665-ac8txr3h 45 9 for for IN cord-277665-ac8txr3h 45 10 example example NN cord-277665-ac8txr3h 45 11 , , , cord-277665-ac8txr3h 45 12 by by IN cord-277665-ac8txr3h 45 13 its -PRON- PRP$ cord-277665-ac8txr3h 45 14 graphitization graphitization NN cord-277665-ac8txr3h 45 15 in in IN cord-277665-ac8txr3h 45 16 a a DT cord-277665-ac8txr3h 45 17 N n CD cord-277665-ac8txr3h 45 18 2 2 CD cord-277665-ac8txr3h 45 19 atmosphere atmosphere NN cord-277665-ac8txr3h 45 20 at at IN cord-277665-ac8txr3h 45 21 1000 1000 CD cord-277665-ac8txr3h 45 22 ° ° NN cord-277665-ac8txr3h 45 23 C c NN cord-277665-ac8txr3h 45 24 followed follow VBN cord-277665-ac8txr3h 45 25 by by IN cord-277665-ac8txr3h 45 26 oxidation oxidation NN cord-277665-ac8txr3h 45 27 in in IN cord-277665-ac8txr3h 45 28 air air NN cord-277665-ac8txr3h 45 29 at at IN cord-277665-ac8txr3h 45 30 450 450 CD cord-277665-ac8txr3h 45 31 ° ° NN cord-277665-ac8txr3h 45 32 C c NN cord-277665-ac8txr3h 45 33 in in IN cord-277665-ac8txr3h 45 34 order order NN cord-277665-ac8txr3h 45 35 to to TO cord-277665-ac8txr3h 45 36 remove remove VB cord-277665-ac8txr3h 45 37 the the DT cord-277665-ac8txr3h 45 38 surface surface NN cord-277665-ac8txr3h 45 39 graphite graphite NN cord-277665-ac8txr3h 45 40 layer layer NN cord-277665-ac8txr3h 45 41 . . . cord-277665-ac8txr3h 46 1 In in IN cord-277665-ac8txr3h 46 2 this this DT cord-277665-ac8txr3h 46 3 way way NN cord-277665-ac8txr3h 46 4 , , , cord-277665-ac8txr3h 46 5 the the DT cord-277665-ac8txr3h 46 6 average average JJ cord-277665-ac8txr3h 46 7 size size NN cord-277665-ac8txr3h 46 8 of of IN cord-277665-ac8txr3h 46 9 ND ND NNP cord-277665-ac8txr3h 46 10 aggregates aggregate NNS cord-277665-ac8txr3h 46 11 can can MD cord-277665-ac8txr3h 46 12 be be VB cord-277665-ac8txr3h 46 13 reduced reduce VBN cord-277665-ac8txr3h 46 14 to to IN cord-277665-ac8txr3h 46 15 50 50 CD cord-277665-ac8txr3h 46 16 nm nm NN cord-277665-ac8txr3h 46 17 or or CC cord-277665-ac8txr3h 46 18 less less JJR cord-277665-ac8txr3h 46 19 with with IN cord-277665-ac8txr3h 46 20 a a DT cord-277665-ac8txr3h 46 21 very very RB cord-277665-ac8txr3h 46 22 high high JJ cord-277665-ac8txr3h 46 23 yield yield NN cord-277665-ac8txr3h 46 24 ( ( -LRB- cord-277665-ac8txr3h 46 25 Xu Xu NNP cord-277665-ac8txr3h 46 26 and and CC cord-277665-ac8txr3h 46 27 Xue Xue NNP cord-277665-ac8txr3h 46 28 , , , cord-277665-ac8txr3h 46 29 2004 2004 CD cord-277665-ac8txr3h 46 30 ) ) -RRB- cord-277665-ac8txr3h 46 31 . . . cord-277665-ac8txr3h 47 1 Dispersion dispersion NN cord-277665-ac8txr3h 47 2 efficiency efficiency NN cord-277665-ac8txr3h 47 3 and and CC cord-277665-ac8txr3h 47 4 stability stability NN cord-277665-ac8txr3h 47 5 of of IN cord-277665-ac8txr3h 47 6 colloidal colloidal NN cord-277665-ac8txr3h 47 7 solutions solution NNS cord-277665-ac8txr3h 47 8 of of IN cord-277665-ac8txr3h 47 9 ND ND NNP cord-277665-ac8txr3h 47 10 in in IN cord-277665-ac8txr3h 47 11 water water NN cord-277665-ac8txr3h 47 12 is be VBZ cord-277665-ac8txr3h 47 13 important important JJ cord-277665-ac8txr3h 47 14 for for IN cord-277665-ac8txr3h 47 15 ND ND NNP cord-277665-ac8txr3h 47 16 applications application NNS cord-277665-ac8txr3h 47 17 in in IN cord-277665-ac8txr3h 47 18 nanobiotechnology nanobiotechnology NN cord-277665-ac8txr3h 47 19 and and CC cord-277665-ac8txr3h 47 20 medicine medicine NN cord-277665-ac8txr3h 47 21 , , , cord-277665-ac8txr3h 47 22 and and CC cord-277665-ac8txr3h 47 23 is be VBZ cord-277665-ac8txr3h 47 24 determined determine VBN cord-277665-ac8txr3h 47 25 by by IN cord-277665-ac8txr3h 47 26 the the DT cord-277665-ac8txr3h 47 27 electrostatic electrostatic JJ cord-277665-ac8txr3h 47 28 , , , cord-277665-ac8txr3h 47 29 hydration hydration NN cord-277665-ac8txr3h 47 30 , , , cord-277665-ac8txr3h 47 31 and and CC cord-277665-ac8txr3h 47 32 hydrophobic hydrophobic JJ cord-277665-ac8txr3h 47 33 ( ( -LRB- cord-277665-ac8txr3h 47 34 the the DT cord-277665-ac8txr3h 47 35 tendency tendency NN cord-277665-ac8txr3h 47 36 of of IN cord-277665-ac8txr3h 47 37 lypophilic lypophilic NNP cord-277665-ac8txr3h 47 38 ND ND NNP cord-277665-ac8txr3h 47 39 to to TO cord-277665-ac8txr3h 47 40 form form VB cord-277665-ac8txr3h 47 41 aggregates aggregate NNS cord-277665-ac8txr3h 47 42 in in IN cord-277665-ac8txr3h 47 43 an an DT cord-277665-ac8txr3h 47 44 aqueous aqueous JJ cord-277665-ac8txr3h 47 45 solution solution NN cord-277665-ac8txr3h 47 46 ) ) -RRB- cord-277665-ac8txr3h 47 47 interactions interaction NNS cord-277665-ac8txr3h 47 48 among among IN cord-277665-ac8txr3h 47 49 the the DT cord-277665-ac8txr3h 47 50 particles particle NNS cord-277665-ac8txr3h 47 51 ( ( -LRB- cord-277665-ac8txr3h 47 52 Xu Xu NNP cord-277665-ac8txr3h 47 53 et et NNP cord-277665-ac8txr3h 47 54 al al NNP cord-277665-ac8txr3h 47 55 . . NNP cord-277665-ac8txr3h 47 56 , , , cord-277665-ac8txr3h 47 57 2005a 2005a CD cord-277665-ac8txr3h 47 58 ) ) -RRB- cord-277665-ac8txr3h 47 59 . . . cord-277665-ac8txr3h 48 1 Within within IN cord-277665-ac8txr3h 48 2 the the DT cord-277665-ac8txr3h 48 3 last last JJ cord-277665-ac8txr3h 48 4 few few JJ cord-277665-ac8txr3h 48 5 years year NNS cord-277665-ac8txr3h 48 6 a a DT cord-277665-ac8txr3h 48 7 number number NN cord-277665-ac8txr3h 48 8 of of IN cord-277665-ac8txr3h 48 9 new new JJ cord-277665-ac8txr3h 48 10 methods method NNS cord-277665-ac8txr3h 48 11 have have VBP cord-277665-ac8txr3h 48 12 been be VBN cord-277665-ac8txr3h 48 13 introduced introduce VBN cord-277665-ac8txr3h 48 14 to to TO cord-277665-ac8txr3h 48 15 control control VB cord-277665-ac8txr3h 48 16 ND ND NNP cord-277665-ac8txr3h 48 17 solubility solubility NN cord-277665-ac8txr3h 48 18 in in IN cord-277665-ac8txr3h 48 19 water water NN cord-277665-ac8txr3h 48 20 by by IN cord-277665-ac8txr3h 48 21 biological biological JJ cord-277665-ac8txr3h 48 22 and and CC cord-277665-ac8txr3h 48 23 chemical chemical JJ cord-277665-ac8txr3h 48 24 modifications modification NNS cord-277665-ac8txr3h 48 25 of of IN cord-277665-ac8txr3h 48 26 the the DT cord-277665-ac8txr3h 48 27 ND ND NNP cord-277665-ac8txr3h 48 28 surface surface NN cord-277665-ac8txr3h 48 29 . . . cord-277665-ac8txr3h 49 1 To to TO cord-277665-ac8txr3h 49 2 obtain obtain VB cord-277665-ac8txr3h 49 3 stable stable JJ cord-277665-ac8txr3h 49 4 suspensions suspension NNS cord-277665-ac8txr3h 49 5 of of IN cord-277665-ac8txr3h 49 6 well well RB cord-277665-ac8txr3h 49 7 - - HYPH cord-277665-ac8txr3h 49 8 dispersed disperse VBN cord-277665-ac8txr3h 49 9 ND ND NNP cord-277665-ac8txr3h 49 10 particles particle NNS cord-277665-ac8txr3h 49 11 in in IN cord-277665-ac8txr3h 49 12 water water NN cord-277665-ac8txr3h 49 13 the the DT cord-277665-ac8txr3h 49 14 mechanochemical mechanochemical JJ cord-277665-ac8txr3h 49 15 procedure procedure NN cord-277665-ac8txr3h 49 16 has have VBZ cord-277665-ac8txr3h 49 17 been be VBN cord-277665-ac8txr3h 49 18 developed develop VBN cord-277665-ac8txr3h 49 19 , , , cord-277665-ac8txr3h 49 20 which which WDT cord-277665-ac8txr3h 49 21 employs employ VBZ cord-277665-ac8txr3h 49 22 a a DT cord-277665-ac8txr3h 49 23 set set NN cord-277665-ac8txr3h 49 24 of of IN cord-277665-ac8txr3h 49 25 different different JJ cord-277665-ac8txr3h 49 26 mechanical mechanical JJ cord-277665-ac8txr3h 49 27 treatments treatment NNS cord-277665-ac8txr3h 49 28 ( ( -LRB- cord-277665-ac8txr3h 49 29 high high JJ cord-277665-ac8txr3h 49 30 - - HYPH cord-277665-ac8txr3h 49 31 power power NN cord-277665-ac8txr3h 49 32 sonification sonification NN cord-277665-ac8txr3h 49 33 or or CC cord-277665-ac8txr3h 49 34 vibration vibration NN cord-277665-ac8txr3h 49 35 milling milling NN cord-277665-ac8txr3h 49 36 techniques technique NNS cord-277665-ac8txr3h 49 37 ) ) -RRB- cord-277665-ac8txr3h 49 38 along along IN cord-277665-ac8txr3h 49 39 with with IN cord-277665-ac8txr3h 49 40 the the DT cord-277665-ac8txr3h 49 41 application application NN cord-277665-ac8txr3h 49 42 of of IN cord-277665-ac8txr3h 49 43 surfactant surfactant NN cord-277665-ac8txr3h 49 44 agents agent NNS cord-277665-ac8txr3h 49 45 ( ( -LRB- cord-277665-ac8txr3h 49 46 Xu Xu NNP cord-277665-ac8txr3h 49 47 et et NNP cord-277665-ac8txr3h 49 48 al al NNP cord-277665-ac8txr3h 49 49 . . NNP cord-277665-ac8txr3h 49 50 , , , cord-277665-ac8txr3h 49 51 2005b 2005b CD cord-277665-ac8txr3h 49 52 ; ; : cord-277665-ac8txr3h 49 53 2005c 2005c CD cord-277665-ac8txr3h 49 54 ) ) -RRB- cord-277665-ac8txr3h 49 55 . . . cord-277665-ac8txr3h 50 1 The the DT cord-277665-ac8txr3h 50 2 mechanochemical mechanochemical JJ cord-277665-ac8txr3h 50 3 modification modification NN cord-277665-ac8txr3h 50 4 with with IN cord-277665-ac8txr3h 50 5 anionic anionic JJ cord-277665-ac8txr3h 50 6 surface surface NN cord-277665-ac8txr3h 50 7 modifiers modifier NNS cord-277665-ac8txr3h 50 8 increased increase VBD cord-277665-ac8txr3h 50 9 the the DT cord-277665-ac8txr3h 50 10 zeta zeta NNP cord-277665-ac8txr3h 50 11 potential potential NN cord-277665-ac8txr3h 50 12 and and CC cord-277665-ac8txr3h 50 13 lowered lower VBD cord-277665-ac8txr3h 50 14 the the DT cord-277665-ac8txr3h 50 15 amount amount NN cord-277665-ac8txr3h 50 16 of of IN cord-277665-ac8txr3h 50 17 hydroxyl hydroxyl NN cord-277665-ac8txr3h 50 18 groups group NNS cord-277665-ac8txr3h 50 19 and and CC cord-277665-ac8txr3h 50 20 the the DT cord-277665-ac8txr3h 50 21 size size NN cord-277665-ac8txr3h 50 22 of of IN cord-277665-ac8txr3h 50 23 individual individual JJ cord-277665-ac8txr3h 50 24 particles particle NNS cord-277665-ac8txr3h 50 25 . . . cord-277665-ac8txr3h 51 1 The the DT cord-277665-ac8txr3h 51 2 mechanochemical mechanochemical JJ cord-277665-ac8txr3h 51 3 processes process NNS cord-277665-ac8txr3h 51 4 were be VBD cord-277665-ac8txr3h 51 5 also also RB cord-277665-ac8txr3h 51 6 successfully successfully RB cord-277665-ac8txr3h 51 7 applied apply VBN cord-277665-ac8txr3h 51 8 for for IN cord-277665-ac8txr3h 51 9 the the DT cord-277665-ac8txr3h 51 10 preparation preparation NN cord-277665-ac8txr3h 51 11 of of IN cord-277665-ac8txr3h 51 12 stable stable JJ cord-277665-ac8txr3h 51 13 highly highly RB cord-277665-ac8txr3h 51 14 dispersed disperse VBN cord-277665-ac8txr3h 51 15 ND ND NNP cord-277665-ac8txr3h 51 16 suspensions suspension NNS cord-277665-ac8txr3h 51 17 in in IN cord-277665-ac8txr3h 51 18 non non JJ cord-277665-ac8txr3h 51 19 - - JJ cord-277665-ac8txr3h 51 20 polar polar JJ cord-277665-ac8txr3h 51 21 solvents solvent NNS cord-277665-ac8txr3h 51 22 : : : cord-277665-ac8txr3h 51 23 an an DT cord-277665-ac8txr3h 51 24 oil oil NN cord-277665-ac8txr3h 51 25 suspension suspension NN cord-277665-ac8txr3h 51 26 of of IN cord-277665-ac8txr3h 51 27 ND ND NNP cord-277665-ac8txr3h 51 28 particles particle NNS cord-277665-ac8txr3h 51 29 with with IN cord-277665-ac8txr3h 51 30 an an DT cord-277665-ac8txr3h 51 31 average average JJ cord-277665-ac8txr3h 51 32 size size NN cord-277665-ac8txr3h 51 33 of of IN cord-277665-ac8txr3h 51 34 55 55 CD cord-277665-ac8txr3h 51 35 nm nm NN cord-277665-ac8txr3h 51 36 was be VBD cord-277665-ac8txr3h 51 37 prepared prepare VBN cord-277665-ac8txr3h 51 38 and and CC cord-277665-ac8txr3h 51 39 stored store VBN cord-277665-ac8txr3h 51 40 for for IN cord-277665-ac8txr3h 51 41 6 6 CD cord-277665-ac8txr3h 51 42 months month NNS cord-277665-ac8txr3h 51 43 without without IN cord-277665-ac8txr3h 51 44 any any DT cord-277665-ac8txr3h 51 45 visible visible JJ cord-277665-ac8txr3h 51 46 signs sign NNS cord-277665-ac8txr3h 51 47 of of IN cord-277665-ac8txr3h 51 48 sedimentation sedimentation NN cord-277665-ac8txr3h 51 49 . . . cord-277665-ac8txr3h 52 1 There there EX cord-277665-ac8txr3h 52 2 has have VBZ cord-277665-ac8txr3h 52 3 been be VBN cord-277665-ac8txr3h 52 4 steady steady JJ cord-277665-ac8txr3h 52 5 progress progress NN cord-277665-ac8txr3h 52 6 in in IN cord-277665-ac8txr3h 52 7 the the DT cord-277665-ac8txr3h 52 8 development development NN cord-277665-ac8txr3h 52 9 of of IN cord-277665-ac8txr3h 52 10 chemical chemical JJ cord-277665-ac8txr3h 52 11 methods method NNS cord-277665-ac8txr3h 52 12 of of IN cord-277665-ac8txr3h 52 13 ND ND NNP cord-277665-ac8txr3h 52 14 surface surface NN cord-277665-ac8txr3h 52 15 modification modification NN cord-277665-ac8txr3h 52 16 as as RB cord-277665-ac8txr3h 52 17 well well RB cord-277665-ac8txr3h 52 18 . . . cord-277665-ac8txr3h 53 1 A a DT cord-277665-ac8txr3h 53 2 summary summary NN cord-277665-ac8txr3h 53 3 of of IN cord-277665-ac8txr3h 53 4 methods method NNS cord-277665-ac8txr3h 53 5 of of IN cord-277665-ac8txr3h 53 6 altering alter VBG cord-277665-ac8txr3h 53 7 the the DT cord-277665-ac8txr3h 53 8 ND ND NNP cord-277665-ac8txr3h 53 9 surface surface NN cord-277665-ac8txr3h 53 10 chemistry chemistry NN cord-277665-ac8txr3h 53 11 with with IN cord-277665-ac8txr3h 53 12 the the DT cord-277665-ac8txr3h 53 13 final final JJ cord-277665-ac8txr3h 53 14 purpose purpose NN cord-277665-ac8txr3h 53 15 of of IN cord-277665-ac8txr3h 53 16 biofunctionalization biofunctionalization NN cord-277665-ac8txr3h 53 17 is be VBZ cord-277665-ac8txr3h 53 18 illustrated illustrate VBN cord-277665-ac8txr3h 53 19 in in IN cord-277665-ac8txr3h 53 20 Fig Fig NNP cord-277665-ac8txr3h 53 21 . . . cord-277665-ac8txr3h 54 1 15 15 CD cord-277665-ac8txr3h 54 2 .2 .2 CD cord-277665-ac8txr3h 54 3 . . . cord-277665-ac8txr3h 55 1 Various various JJ cord-277665-ac8txr3h 55 2 organic organic JJ cord-277665-ac8txr3h 55 3 molecules molecule NNS cord-277665-ac8txr3h 55 4 can can MD cord-277665-ac8txr3h 55 5 be be VB cord-277665-ac8txr3h 55 6 attached attach VBN cord-277665-ac8txr3h 55 7 to to IN cord-277665-ac8txr3h 55 8 polycrystalline polycrystalline JJ cord-277665-ac8txr3h 55 9 diamond diamond NN cord-277665-ac8txr3h 55 10 films film NNS cord-277665-ac8txr3h 55 11 when when WRB cord-277665-ac8txr3h 55 12 under under IN cord-277665-ac8txr3h 55 13 irradiation irradiation NN cord-277665-ac8txr3h 55 14 with with IN cord-277665-ac8txr3h 55 15 UV uv NN cord-277665-ac8txr3h 55 16 light light NN cord-277665-ac8txr3h 55 17 . . . cord-277665-ac8txr3h 56 1 Prior prior RB cord-277665-ac8txr3h 56 2 to to IN cord-277665-ac8txr3h 56 3 exposure exposure NN cord-277665-ac8txr3h 56 4 to to IN cord-277665-ac8txr3h 56 5 UV uv NN cord-277665-ac8txr3h 56 6 light light VB cord-277665-ac8txr3h 56 7 the the DT cord-277665-ac8txr3h 56 8 hydrogen hydrogen NN cord-277665-ac8txr3h 56 9 - - HYPH cord-277665-ac8txr3h 56 10 terminated terminate VBN cord-277665-ac8txr3h 56 11 diamond diamond NN cord-277665-ac8txr3h 56 12 surface surface NN cord-277665-ac8txr3h 56 13 must must MD cord-277665-ac8txr3h 56 14 be be VB cord-277665-ac8txr3h 56 15 coated coat VBN cord-277665-ac8txr3h 56 16 with with IN cord-277665-ac8txr3h 56 17 a a DT cord-277665-ac8txr3h 56 18 thin thin JJ cord-277665-ac8txr3h 56 19 film film NN cord-277665-ac8txr3h 56 20 of of IN cord-277665-ac8txr3h 56 21 the the DT cord-277665-ac8txr3h 56 22 solution solution NN cord-277665-ac8txr3h 56 23 containing contain VBG cord-277665-ac8txr3h 56 24 organic organic JJ cord-277665-ac8txr3h 56 25 molecules molecule NNS cord-277665-ac8txr3h 56 26 in in IN cord-277665-ac8txr3h 56 27 order order NN cord-277665-ac8txr3h 56 28 to to TO cord-277665-ac8txr3h 56 29 be be VB cord-277665-ac8txr3h 56 30 immobilized immobilize VBN cord-277665-ac8txr3h 56 31 . . . cord-277665-ac8txr3h 57 1 By by IN cord-277665-ac8txr3h 57 2 attaching attach VBG cord-277665-ac8txr3h 57 3 molecules molecule NNS cord-277665-ac8txr3h 57 4 with with IN cord-277665-ac8txr3h 57 5 specific specific JJ cord-277665-ac8txr3h 57 6 protecting protect VBG cord-277665-ac8txr3h 57 7 groups group NNS cord-277665-ac8txr3h 57 8 and and CC cord-277665-ac8txr3h 57 9 removing remove VBG cord-277665-ac8txr3h 57 10 protecting protect VBG cord-277665-ac8txr3h 57 11 groups group NNS cord-277665-ac8txr3h 57 12 after after IN cord-277665-ac8txr3h 57 13 the the DT cord-277665-ac8txr3h 57 14 attachment attachment NN cord-277665-ac8txr3h 57 15 , , , cord-277665-ac8txr3h 57 16 it -PRON- PRP cord-277665-ac8txr3h 57 17 is be VBZ cord-277665-ac8txr3h 57 18 possible possible JJ cord-277665-ac8txr3h 57 19 to to TO cord-277665-ac8txr3h 57 20 obtain obtain VB cord-277665-ac8txr3h 57 21 diamond diamond NN cord-277665-ac8txr3h 57 22 surfaces surface NNS cord-277665-ac8txr3h 57 23 functionalized functionalize VBN cord-277665-ac8txr3h 57 24 with with IN cord-277665-ac8txr3h 57 25 carboxyl carboxyl NN cord-277665-ac8txr3h 57 26 or or CC cord-277665-ac8txr3h 57 27 primary primary JJ cord-277665-ac8txr3h 57 28 amine amine NN cord-277665-ac8txr3h 57 29 groups group NNS cord-277665-ac8txr3h 57 30 that that WDT cord-277665-ac8txr3h 57 31 may may MD cord-277665-ac8txr3h 57 32 facilitate facilitate VB cord-277665-ac8txr3h 57 33 further further JJ cord-277665-ac8txr3h 57 34 steps step NNS cord-277665-ac8txr3h 57 35 in in IN cord-277665-ac8txr3h 57 36 chemical chemical JJ cord-277665-ac8txr3h 57 37 modification modification NN cord-277665-ac8txr3h 57 38 of of IN cord-277665-ac8txr3h 57 39 diamond diamond NN cord-277665-ac8txr3h 57 40 surfaces surface NNS cord-277665-ac8txr3h 57 41 such such JJ cord-277665-ac8txr3h 57 42 as as IN cord-277665-ac8txr3h 57 43 DNA dna NN cord-277665-ac8txr3h 57 44 and and CC cord-277665-ac8txr3h 57 45 protein protein NN cord-277665-ac8txr3h 57 46 immobilization immobilization NN cord-277665-ac8txr3h 57 47 ( ( -LRB- cord-277665-ac8txr3h 57 48 Strother Strother NNP cord-277665-ac8txr3h 57 49 et et NNP cord-277665-ac8txr3h 57 50 al al NNP cord-277665-ac8txr3h 57 51 . . NNP cord-277665-ac8txr3h 57 52 , , , cord-277665-ac8txr3h 57 53 2002 2002 CD cord-277665-ac8txr3h 57 54 ) ) -RRB- cord-277665-ac8txr3h 57 55 . . . cord-277665-ac8txr3h 58 1 To to TO cord-277665-ac8txr3h 58 2 increase increase VB cord-277665-ac8txr3h 58 3 ND ND NNP cord-277665-ac8txr3h 58 4 solubility solubility NN cord-277665-ac8txr3h 58 5 in in IN cord-277665-ac8txr3h 58 6 water water NN cord-277665-ac8txr3h 58 7 and and CC cord-277665-ac8txr3h 58 8 prepare prepare VB cord-277665-ac8txr3h 58 9 the the DT cord-277665-ac8txr3h 58 10 ND ND NNP cord-277665-ac8txr3h 58 11 surface surface NN cord-277665-ac8txr3h 58 12 for for IN cord-277665-ac8txr3h 58 13 biomolecule biomolecule NN cord-277665-ac8txr3h 58 14 attachment attachment NN cord-277665-ac8txr3h 58 15 , , , cord-277665-ac8txr3h 58 16 oxidation oxidation NN cord-277665-ac8txr3h 58 17 of of IN cord-277665-ac8txr3h 58 18 the the DT cord-277665-ac8txr3h 58 19 ND ND NNP cord-277665-ac8txr3h 58 20 surface surface NN cord-277665-ac8txr3h 58 21 is be VBZ cord-277665-ac8txr3h 58 22 frequently frequently RB cord-277665-ac8txr3h 58 23 required require VBN cord-277665-ac8txr3h 58 24 ( ( -LRB- cord-277665-ac8txr3h 58 25 Fig fig NN cord-277665-ac8txr3h 58 26 . . . cord-277665-ac8txr3h 58 27 15.2 15.2 CD cord-277665-ac8txr3h 58 28 ) ) -RRB- cord-277665-ac8txr3h 58 29 . . . cord-277665-ac8txr3h 59 1 Under under IN cord-277665-ac8txr3h 59 2 mild mild JJ cord-277665-ac8txr3h 59 3 conditions condition NNS cord-277665-ac8txr3h 59 4 the the DT cord-277665-ac8txr3h 59 5 diamond diamond NN cord-277665-ac8txr3h 59 6 surface surface NN cord-277665-ac8txr3h 59 7 can can MD cord-277665-ac8txr3h 59 8 be be VB cord-277665-ac8txr3h 59 9 directly directly RB cord-277665-ac8txr3h 59 10 functionalized functionalize VBN cord-277665-ac8txr3h 59 11 with with IN cord-277665-ac8txr3h 59 12 carboxylic carboxylic JJ cord-277665-ac8txr3h 59 13 acids acid NNS cord-277665-ac8txr3h 59 14 by by IN cord-277665-ac8txr3h 59 15 initiating initiate VBG cord-277665-ac8txr3h 59 16 radical radical JJ cord-277665-ac8txr3h 59 17 reactions reaction NNS cord-277665-ac8txr3h 59 18 ( ( -LRB- cord-277665-ac8txr3h 59 19 Tsubota Tsubota NNP cord-277665-ac8txr3h 59 20 et et NNP cord-277665-ac8txr3h 59 21 al al NNP cord-277665-ac8txr3h 59 22 . . NNP cord-277665-ac8txr3h 59 23 , , , cord-277665-ac8txr3h 59 24 2004 2004 CD cord-277665-ac8txr3h 59 25 ) ) -RRB- cord-277665-ac8txr3h 59 26 . . . cord-277665-ac8txr3h 60 1 However however RB cord-277665-ac8txr3h 60 2 , , , cord-277665-ac8txr3h 60 3 the the DT cord-277665-ac8txr3h 60 4 number number NN cord-277665-ac8txr3h 60 5 of of IN cord-277665-ac8txr3h 60 6 carboxylic carboxylic JJ cord-277665-ac8txr3h 60 7 acid acid NN cord-277665-ac8txr3h 60 8 residues residue NNS cord-277665-ac8txr3h 60 9 introduced introduce VBN cord-277665-ac8txr3h 60 10 on on IN cord-277665-ac8txr3h 60 11 the the DT cord-277665-ac8txr3h 60 12 diamond diamond NN cord-277665-ac8txr3h 60 13 surface surface NN cord-277665-ac8txr3h 60 14 may may MD cord-277665-ac8txr3h 60 15 be be VB cord-277665-ac8txr3h 60 16 low low JJ cord-277665-ac8txr3h 60 17 in in IN cord-277665-ac8txr3h 60 18 some some DT cord-277665-ac8txr3h 60 19 cases case NNS cord-277665-ac8txr3h 60 20 . . . cord-277665-ac8txr3h 61 1 Indeed indeed RB cord-277665-ac8txr3h 61 2 , , , cord-277665-ac8txr3h 61 3 oxidation oxidation NN cord-277665-ac8txr3h 61 4 of of IN cord-277665-ac8txr3h 61 5 ND ND NNP cord-277665-ac8txr3h 61 6 does do VBZ cord-277665-ac8txr3h 61 7 not not RB cord-277665-ac8txr3h 61 8 proceed proceed VB cord-277665-ac8txr3h 61 9 easily easily RB cord-277665-ac8txr3h 61 10 under under IN cord-277665-ac8txr3h 61 11 the the DT cord-277665-ac8txr3h 61 12 mild mild JJ cord-277665-ac8txr3h 61 13 conditions condition NNS cord-277665-ac8txr3h 61 14 . . . cord-277665-ac8txr3h 62 1 In in IN cord-277665-ac8txr3h 62 2 an an DT cord-277665-ac8txr3h 62 3 aqueous aqueous JJ cord-277665-ac8txr3h 62 4 slurry slurry NN cord-277665-ac8txr3h 62 5 , , , cord-277665-ac8txr3h 62 6 ND ND NNP cord-277665-ac8txr3h 62 7 of of IN cord-277665-ac8txr3h 62 8 4 4 CD cord-277665-ac8txr3h 62 9 nm nm NN cord-277665-ac8txr3h 62 10 size size NN cord-277665-ac8txr3h 62 11 may may MD cord-277665-ac8txr3h 62 12 react react VB cord-277665-ac8txr3h 62 13 with with IN cord-277665-ac8txr3h 62 14 ozone ozone NN cord-277665-ac8txr3h 62 15 , , , cord-277665-ac8txr3h 62 16 though though IN cord-277665-ac8txr3h 62 17 a a DT cord-277665-ac8txr3h 62 18 very very RB cord-277665-ac8txr3h 62 19 long long JJ cord-277665-ac8txr3h 62 20 time time NN cord-277665-ac8txr3h 62 21 is be VBZ cord-277665-ac8txr3h 62 22 needed need VBN cord-277665-ac8txr3h 62 23 in in IN cord-277665-ac8txr3h 62 24 order order NN cord-277665-ac8txr3h 62 25 to to TO cord-277665-ac8txr3h 62 26 functionalize functionalize VB cord-277665-ac8txr3h 62 27 the the DT cord-277665-ac8txr3h 62 28 surface surface NN cord-277665-ac8txr3h 62 29 of of IN cord-277665-ac8txr3h 62 30 ND ND NNP cord-277665-ac8txr3h 62 31 with with IN cord-277665-ac8txr3h 62 32 the the DT cord-277665-ac8txr3h 62 33 ketonic ketonic JJ cord-277665-ac8txr3h 62 34 groups group NNS cord-277665-ac8txr3h 62 35 ( ( -LRB- cord-277665-ac8txr3h 62 36 Cataldo Cataldo NNP cord-277665-ac8txr3h 62 37 and and CC cord-277665-ac8txr3h 62 38 Koscheev Koscheev NNP cord-277665-ac8txr3h 62 39 , , , cord-277665-ac8txr3h 62 40 2003 2003 CD cord-277665-ac8txr3h 62 41 ) ) -RRB- cord-277665-ac8txr3h 62 42 . . . cord-277665-ac8txr3h 63 1 In in IN cord-277665-ac8txr3h 63 2 air air NN cord-277665-ac8txr3h 63 3 ND ND NNP cord-277665-ac8txr3h 63 4 may may MD cord-277665-ac8txr3h 63 5 suddenly suddenly RB cord-277665-ac8txr3h 63 6 explode explode VB cord-277665-ac8txr3h 63 7 15 15 CD cord-277665-ac8txr3h 63 8 : : : cord-277665-ac8txr3h 63 9 Designing design VBG cord-277665-ac8txr3h 63 10 the the DT cord-277665-ac8txr3h 63 11 Bio Bio NNP cord-277665-ac8txr3h 63 12 - - HYPH cord-277665-ac8txr3h 63 13 Platform Platform NNP cord-277665-ac8txr3h 63 14 , , , cord-277665-ac8txr3h 63 15 Grichko Grichko NNP cord-277665-ac8txr3h 63 16 and and CC cord-277665-ac8txr3h 63 17 Shenderova Shenderova NNP cord-277665-ac8txr3h 64 1 533 533 CD cord-277665-ac8txr3h 64 2 above above IN cord-277665-ac8txr3h 64 3 a a DT cord-277665-ac8txr3h 64 4 temperature temperature NN cord-277665-ac8txr3h 64 5 of of IN cord-277665-ac8txr3h 64 6 450 450 CD cord-277665-ac8txr3h 64 7 ° ° NN cord-277665-ac8txr3h 64 8 C c NN cord-277665-ac8txr3h 64 9 . . . cord-277665-ac8txr3h 65 1 The the DT cord-277665-ac8txr3h 65 2 functionalization functionalization NN cord-277665-ac8txr3h 65 3 of of IN cord-277665-ac8txr3h 65 4 NDs nd NNS cord-277665-ac8txr3h 65 5 at at IN cord-277665-ac8txr3h 65 6 elevated elevated JJ cord-277665-ac8txr3h 65 7 temperature temperature NN cord-277665-ac8txr3h 65 8 affects affect VBZ cord-277665-ac8txr3h 65 9 both both CC cord-277665-ac8txr3h 65 10 their -PRON- PRP$ cord-277665-ac8txr3h 65 11 size size NN cord-277665-ac8txr3h 65 12 and and CC cord-277665-ac8txr3h 65 13 surface surface NN cord-277665-ac8txr3h 65 14 chemistry chemistry NN cord-277665-ac8txr3h 65 15 . . . cord-277665-ac8txr3h 66 1 The the DT cord-277665-ac8txr3h 66 2 weight weight NN cord-277665-ac8txr3h 66 3 of of IN cord-277665-ac8txr3h 66 4 ND ND NNP cord-277665-ac8txr3h 66 5 particles particle NNS cord-277665-ac8txr3h 66 6 was be VBD cord-277665-ac8txr3h 66 7 reported report VBN cord-277665-ac8txr3h 66 8 to to TO cord-277665-ac8txr3h 66 9 decline decline VB cord-277665-ac8txr3h 66 10 by by IN cord-277665-ac8txr3h 66 11 11.5 11.5 CD cord-277665-ac8txr3h 66 12 % % NN cord-277665-ac8txr3h 66 13 as as IN cord-277665-ac8txr3h 66 14 a a DT cord-277665-ac8txr3h 66 15 result result NN cord-277665-ac8txr3h 66 16 of of IN cord-277665-ac8txr3h 66 17 heating heating NN cord-277665-ac8txr3h 66 18 at at IN cord-277665-ac8txr3h 66 19 900 900 CD cord-277665-ac8txr3h 66 20 ° ° NN cord-277665-ac8txr3h 66 21 C c NN cord-277665-ac8txr3h 66 22 in in IN cord-277665-ac8txr3h 66 23 an an DT cord-277665-ac8txr3h 66 24 inert inert JJ cord-277665-ac8txr3h 66 25 atmosphere atmosphere NN cord-277665-ac8txr3h 66 26 ( ( -LRB- cord-277665-ac8txr3h 66 27 Cataldo Cataldo NNP cord-277665-ac8txr3h 66 28 and and CC cord-277665-ac8txr3h 66 29 Koscheev Koscheev NNP cord-277665-ac8txr3h 66 30 , , , cord-277665-ac8txr3h 66 31 2003 2003 CD cord-277665-ac8txr3h 66 32 ) ) -RRB- cord-277665-ac8txr3h 66 33 . . . cord-277665-ac8txr3h 67 1 Spherical spherical JJ cord-277665-ac8txr3h 67 2 diamond diamond NN cord-277665-ac8txr3h 67 3 powder powder NN cord-277665-ac8txr3h 67 4 with with IN cord-277665-ac8txr3h 67 5 a a DT cord-277665-ac8txr3h 67 6 particle particle NN cord-277665-ac8txr3h 67 7 size size NN cord-277665-ac8txr3h 67 8 ranging range VBG cord-277665-ac8txr3h 67 9 from from IN cord-277665-ac8txr3h 67 10 150 150 CD cord-277665-ac8txr3h 67 11 to to IN cord-277665-ac8txr3h 67 12 600 600 CD cord-277665-ac8txr3h 67 13 nm nm NN cord-277665-ac8txr3h 67 14 can can MD cord-277665-ac8txr3h 67 15 be be VB cord-277665-ac8txr3h 67 16 oxidized oxidize VBN cord-277665-ac8txr3h 67 17 in in IN cord-277665-ac8txr3h 67 18 an an DT cord-277665-ac8txr3h 67 19 oxygen oxygen NN cord-277665-ac8txr3h 67 20 atmosphere atmosphere NN cord-277665-ac8txr3h 67 21 at at IN cord-277665-ac8txr3h 67 22 450 450 CD cord-277665-ac8txr3h 67 23 - - SYM cord-277665-ac8txr3h 67 24 610 610 CD cord-277665-ac8txr3h 67 25 ° ° NN cord-277665-ac8txr3h 67 26 C C NNP cord-277665-ac8txr3h 67 27 ( ( -LRB- cord-277665-ac8txr3h 67 28 Lee Lee NNP cord-277665-ac8txr3h 67 29 et et NNP cord-277665-ac8txr3h 67 30 al al NNP cord-277665-ac8txr3h 67 31 . . NNP cord-277665-ac8txr3h 67 32 , , , cord-277665-ac8txr3h 67 33 2004 2004 CD cord-277665-ac8txr3h 67 34 ) ) -RRB- cord-277665-ac8txr3h 67 35 . . . cord-277665-ac8txr3h 68 1 The the DT cord-277665-ac8txr3h 68 2 oxidized oxidized JJ cord-277665-ac8txr3h 68 3 diamond diamond NN cord-277665-ac8txr3h 68 4 powders powder NNS cord-277665-ac8txr3h 68 5 were be VBD cord-277665-ac8txr3h 68 6 further further RB cord-277665-ac8txr3h 68 7 successfully successfully RB cord-277665-ac8txr3h 68 8 functionalized functionalize VBN cord-277665-ac8txr3h 68 9 by by IN cord-277665-ac8txr3h 68 10 reacting react VBG cord-277665-ac8txr3h 68 11 with with IN cord-277665-ac8txr3h 68 12 4-(trifluoromethyl)benzylamine 4-(trifluoromethyl)benzylamine CD cord-277665-ac8txr3h 68 13 containing contain VBG cord-277665-ac8txr3h 68 14 the the DT cord-277665-ac8txr3h 68 15 reactive reactive JJ cord-277665-ac8txr3h 68 16 amino amino NN cord-277665-ac8txr3h 68 17 group group NN cord-277665-ac8txr3h 68 18 . . . cord-277665-ac8txr3h 69 1 Under under IN cord-277665-ac8txr3h 69 2 certain certain JJ cord-277665-ac8txr3h 69 3 conditions condition NNS cord-277665-ac8txr3h 69 4 the the DT cord-277665-ac8txr3h 69 5 high high JJ cord-277665-ac8txr3h 69 6 rate rate NN cord-277665-ac8txr3h 69 7 of of IN cord-277665-ac8txr3h 69 8 diamond diamond NN cord-277665-ac8txr3h 69 9 oxidation oxidation NN cord-277665-ac8txr3h 69 10 may may MD cord-277665-ac8txr3h 69 11 result result VB cord-277665-ac8txr3h 69 12 in in IN cord-277665-ac8txr3h 69 13 an an DT cord-277665-ac8txr3h 69 14 explosive explosive JJ cord-277665-ac8txr3h 69 15 process process NN cord-277665-ac8txr3h 69 16 . . . cord-277665-ac8txr3h 70 1 Ida Ida NNP cord-277665-ac8txr3h 70 2 et et NNP cord-277665-ac8txr3h 70 3 al al NNP cord-277665-ac8txr3h 70 4 . . . cord-277665-ac8txr3h 71 1 ( ( -LRB- cord-277665-ac8txr3h 71 2 2003 2003 CD cord-277665-ac8txr3h 71 3 ) ) -RRB- cord-277665-ac8txr3h 71 4 have have VBP cord-277665-ac8txr3h 71 5 investigated investigate VBN cord-277665-ac8txr3h 71 6 the the DT cord-277665-ac8txr3h 71 7 reactivity reactivity NN cord-277665-ac8txr3h 71 8 of of IN cord-277665-ac8txr3h 71 9 hydrogenated hydrogenate VBN cord-277665-ac8txr3h 71 10 diamond diamond NN cord-277665-ac8txr3h 71 11 surfaces surface NNS cord-277665-ac8txr3h 71 12 with with IN cord-277665-ac8txr3h 71 13 peroxide peroxide NN cord-277665-ac8txr3h 71 14 radical radical JJ cord-277665-ac8txr3h 71 15 initiators initiator NNS cord-277665-ac8txr3h 71 16 such such JJ cord-277665-ac8txr3h 71 17 as as IN cord-277665-ac8txr3h 71 18 benzoyl benzoyl NN cord-277665-ac8txr3h 71 19 peroxide peroxide NN cord-277665-ac8txr3h 71 20 , , , cord-277665-ac8txr3h 71 21 lauroyl lauroyl NNP cord-277665-ac8txr3h 71 22 peroxide peroxide NN cord-277665-ac8txr3h 71 23 , , , cord-277665-ac8txr3h 71 24 dicumyl dicumyl NN cord-277665-ac8txr3h 71 25 peroxide peroxide NN cord-277665-ac8txr3h 71 26 , , , cord-277665-ac8txr3h 71 27 and and CC cord-277665-ac8txr3h 71 28 di di NN cord-277665-ac8txr3h 71 29 - - HYPH cord-277665-ac8txr3h 71 30 t t NN cord-277665-ac8txr3h 71 31 - - HYPH cord-277665-ac8txr3h 71 32 butyl butyl NN cord-277665-ac8txr3h 71 33 peroxide peroxide NN cord-277665-ac8txr3h 71 34 . . . cord-277665-ac8txr3h 72 1 With with IN cord-277665-ac8txr3h 72 2 benzoyl benzoyl NN cord-277665-ac8txr3h 72 3 peroxide peroxide NN cord-277665-ac8txr3h 72 4 , , , cord-277665-ac8txr3h 72 5 they -PRON- PRP cord-277665-ac8txr3h 72 6 detected detect VBD cord-277665-ac8txr3h 72 7 IR IR NNP cord-277665-ac8txr3h 72 8 peaks peak NNS cord-277665-ac8txr3h 72 9 that that WDT cord-277665-ac8txr3h 72 10 were be VBD cord-277665-ac8txr3h 72 11 then then RB cord-277665-ac8txr3h 72 12 assigned assign VBN cord-277665-ac8txr3h 72 13 to to IN cord-277665-ac8txr3h 72 14 the the DT cord-277665-ac8txr3h 72 15 aromatic aromatic JJ cord-277665-ac8txr3h 72 16 C C NNP cord-277665-ac8txr3h 72 17 - - HYPH cord-277665-ac8txr3h 72 18 H H NNP cord-277665-ac8txr3h 72 19 and and CC cord-277665-ac8txr3h 72 20 C c NN cord-277665-ac8txr3h 72 21 = = SYM cord-277665-ac8txr3h 72 22 O o NN cord-277665-ac8txr3h 72 23 stretching stretch VBG cord-277665-ac8txr3h 72 24 vibrations vibration NNS cord-277665-ac8txr3h 72 25 . . . cord-277665-ac8txr3h 73 1 The the DT cord-277665-ac8txr3h 73 2 C c NN cord-277665-ac8txr3h 73 3 = = SYM cord-277665-ac8txr3h 73 4 O o NN cord-277665-ac8txr3h 73 5 stretching stretch VBG cord-277665-ac8txr3h 73 6 vibration vibration NN cord-277665-ac8txr3h 73 7 was be VBD cord-277665-ac8txr3h 73 8 observed observe VBN cord-277665-ac8txr3h 73 9 after after IN cord-277665-ac8txr3h 73 10 the the DT cord-277665-ac8txr3h 73 11 diamond diamond NN cord-277665-ac8txr3h 73 12 was be VBD cord-277665-ac8txr3h 73 13 exposed expose VBN cord-277665-ac8txr3h 73 14 to to IN cord-277665-ac8txr3h 73 15 lauroyl lauroyl NNP cord-277665-ac8txr3h 73 16 peroxide peroxide NN cord-277665-ac8txr3h 73 17 . . . cord-277665-ac8txr3h 74 1 The the DT cord-277665-ac8txr3h 74 2 areas area NNS cord-277665-ac8txr3h 74 3 under under IN cord-277665-ac8txr3h 74 4 the the DT cord-277665-ac8txr3h 74 5 peak peak NN cord-277665-ac8txr3h 74 6 of of IN cord-277665-ac8txr3h 74 7 spectra spectrum NNS cord-277665-ac8txr3h 74 8 determined determine VBN cord-277665-ac8txr3h 74 9 with with IN cord-277665-ac8txr3h 74 10 Fourier Fourier NNP cord-277665-ac8txr3h 74 11 transform transform VB cord-277665-ac8txr3h 74 12 infrared infrared JJ cord-277665-ac8txr3h 74 13 spectroscopy spectroscopy NN cord-277665-ac8txr3h 74 14 ( ( -LRB- cord-277665-ac8txr3h 74 15 FTIR FTIR NNP cord-277665-ac8txr3h 74 16 ) ) -RRB- cord-277665-ac8txr3h 74 17 increased increase VBD cord-277665-ac8txr3h 74 18 with with IN cord-277665-ac8txr3h 74 19 reaction reaction NN cord-277665-ac8txr3h 74 20 time time NN cord-277665-ac8txr3h 74 21 and and CC cord-277665-ac8txr3h 74 22 amount amount NN cord-277665-ac8txr3h 74 23 of of IN cord-277665-ac8txr3h 74 24 reagent reagent NN cord-277665-ac8txr3h 74 25 . . . cord-277665-ac8txr3h 75 1 Dicumyl dicumyl JJ cord-277665-ac8txr3h 75 2 peroxide peroxide NN cord-277665-ac8txr3h 75 3 and and CC cord-277665-ac8txr3h 75 4 di di NN cord-277665-ac8txr3h 75 5 - - HYPH cord-277665-ac8txr3h 75 6 t t NN cord-277665-ac8txr3h 75 7 - - HYPH cord-277665-ac8txr3h 75 8 butyl butyl NN cord-277665-ac8txr3h 75 9 peroxide peroxide NN cord-277665-ac8txr3h 75 10 did do VBD cord-277665-ac8txr3h 75 11 not not RB cord-277665-ac8txr3h 75 12 react react VB cord-277665-ac8txr3h 75 13 with with IN cord-277665-ac8txr3h 75 14 diamond diamond NN cord-277665-ac8txr3h 75 15 surfaces surface NNS cord-277665-ac8txr3h 75 16 . . . cord-277665-ac8txr3h 76 1 While while IN cord-277665-ac8txr3h 76 2 the the DT cord-277665-ac8txr3h 76 3 yield yield NN cord-277665-ac8txr3h 76 4 of of IN cord-277665-ac8txr3h 76 5 reaction reaction NN cord-277665-ac8txr3h 76 6 of of IN cord-277665-ac8txr3h 76 7 diamond diamond NN cord-277665-ac8txr3h 76 8 surface surface NN cord-277665-ac8txr3h 76 9 with with IN cord-277665-ac8txr3h 76 10 radical radical JJ cord-277665-ac8txr3h 76 11 species specie NNS cord-277665-ac8txr3h 76 12 generated generate VBN cord-277665-ac8txr3h 76 13 from from IN cord-277665-ac8txr3h 76 14 benzoyl benzoyl JJ cord-277665-ac8txr3h 76 15 peroxide peroxide NN cord-277665-ac8txr3h 76 16 depends depend VBZ cord-277665-ac8txr3h 76 17 on on IN cord-277665-ac8txr3h 76 18 the the DT cord-277665-ac8txr3h 76 19 organic organic JJ cord-277665-ac8txr3h 76 20 solvent solvent NN cord-277665-ac8txr3h 76 21 used use VBD cord-277665-ac8txr3h 76 22 , , , cord-277665-ac8txr3h 76 23 the the DT cord-277665-ac8txr3h 76 24 same same JJ cord-277665-ac8txr3h 76 25 functional functional JJ cord-277665-ac8txr3h 76 26 groups group NNS cord-277665-ac8txr3h 76 27 were be VBD cord-277665-ac8txr3h 76 28 synthesized synthesize VBN cord-277665-ac8txr3h 76 29 in in IN cord-277665-ac8txr3h 76 30 toluene toluene NN cord-277665-ac8txr3h 76 31 , , , cord-277665-ac8txr3h 76 32 tetrahydrofuran tetrahydrofuran NN cord-277665-ac8txr3h 76 33 , , , cord-277665-ac8txr3h 76 34 N N NNP cord-277665-ac8txr3h 76 35 , , , cord-277665-ac8txr3h 76 36 Ndimethylformamide Ndimethylformamide NNP cord-277665-ac8txr3h 76 37 , , , cord-277665-ac8txr3h 76 38 cyclohexane cyclohexane NNP cord-277665-ac8txr3h 76 39 , , , cord-277665-ac8txr3h 76 40 and and CC cord-277665-ac8txr3h 76 41 hexane hexane NNP cord-277665-ac8txr3h 76 42 ( ( -LRB- cord-277665-ac8txr3h 77 1 Tsubota Tsubota NNP cord-277665-ac8txr3h 77 2 et et NNP cord-277665-ac8txr3h 77 3 al al NNP cord-277665-ac8txr3h 77 4 . . NNP cord-277665-ac8txr3h 77 5 , , , cord-277665-ac8txr3h 77 6 2002a 2002a CD cord-277665-ac8txr3h 77 7 ) ) -RRB- cord-277665-ac8txr3h 77 8 . . . cord-277665-ac8txr3h 78 1 The the DT cord-277665-ac8txr3h 78 2 hydroxyl hydroxyl NN cord-277665-ac8txr3h 78 3 groups group NNS cord-277665-ac8txr3h 78 4 located locate VBN cord-277665-ac8txr3h 78 5 on on IN cord-277665-ac8txr3h 78 6 the the DT cord-277665-ac8txr3h 78 7 surface surface NN cord-277665-ac8txr3h 78 8 of of IN cord-277665-ac8txr3h 78 9 diamond diamond NN cord-277665-ac8txr3h 78 10 powders powder NNS cord-277665-ac8txr3h 78 11 , , , cord-277665-ac8txr3h 78 12 which which WDT cord-277665-ac8txr3h 78 13 was be VBD cord-277665-ac8txr3h 78 14 treated treat VBN cord-277665-ac8txr3h 78 15 either either CC cord-277665-ac8txr3h 78 16 with with IN cord-277665-ac8txr3h 78 17 sulfuric sulfuric JJ cord-277665-ac8txr3h 78 18 acid acid NN cord-277665-ac8txr3h 78 19 alone alone RB cord-277665-ac8txr3h 78 20 or or CC cord-277665-ac8txr3h 78 21 with with IN cord-277665-ac8txr3h 78 22 a a DT cord-277665-ac8txr3h 78 23 mixture mixture NN cord-277665-ac8txr3h 78 24 of of IN cord-277665-ac8txr3h 78 25 sulfuric sulfuric JJ cord-277665-ac8txr3h 78 26 and and CC cord-277665-ac8txr3h 78 27 nitric nitric JJ cord-277665-ac8txr3h 78 28 acids acid NNS cord-277665-ac8txr3h 78 29 , , , cord-277665-ac8txr3h 78 30 can can MD cord-277665-ac8txr3h 78 31 be be VB cord-277665-ac8txr3h 78 32 reacted react VBN cord-277665-ac8txr3h 78 33 with with IN cord-277665-ac8txr3h 78 34 metoxy metoxy JJ cord-277665-ac8txr3h 78 35 groups group NNS cord-277665-ac8txr3h 78 36 of of IN cord-277665-ac8txr3h 78 37 silanecoupling silanecouple VBG cord-277665-ac8txr3h 78 38 reagents reagent NNS cord-277665-ac8txr3h 78 39 ( ( -LRB- cord-277665-ac8txr3h 78 40 3-aminopropyltrimethoxysilane 3-aminopropyltrimethoxysilane CD cord-277665-ac8txr3h 78 41 , , , cord-277665-ac8txr3h 78 42 3-mercaptopropyltrimethoxysilane 3-mercaptopropyltrimethoxysilane CD cord-277665-ac8txr3h 78 43 , , , cord-277665-ac8txr3h 78 44 or or CC cord-277665-ac8txr3h 78 45 n n NN cord-277665-ac8txr3h 78 46 - - HYPH cord-277665-ac8txr3h 78 47 octyltrimethoxysilane octyltrimethoxysilane NNP cord-277665-ac8txr3h 78 48 ) ) -RRB- cord-277665-ac8txr3h 78 49 with with IN cord-277665-ac8txr3h 78 50 the the DT cord-277665-ac8txr3h 78 51 formation formation NN cord-277665-ac8txr3h 78 52 of of IN cord-277665-ac8txr3h 78 53 stable stable JJ cord-277665-ac8txr3h 78 54 modified modified JJ cord-277665-ac8txr3h 78 55 diamonds diamond NNS cord-277665-ac8txr3h 79 1 ( ( -LRB- cord-277665-ac8txr3h 79 2 Tsubota Tsubota NNP cord-277665-ac8txr3h 79 3 et et NNP cord-277665-ac8txr3h 79 4 al al NNP cord-277665-ac8txr3h 79 5 . . . cord-277665-ac8txr3h 80 1 , , , cord-277665-ac8txr3h 80 2 2002b 2002b CD cord-277665-ac8txr3h 80 3 ) ) -RRB- cord-277665-ac8txr3h 80 4 . . . cord-277665-ac8txr3h 81 1 The the DT cord-277665-ac8txr3h 81 2 silane silane NN cord-277665-ac8txr3h 81 3 - - HYPH cord-277665-ac8txr3h 81 4 modified modify VBN cord-277665-ac8txr3h 81 5 NDs nd NNS cord-277665-ac8txr3h 81 6 can can MD cord-277665-ac8txr3h 81 7 be be VB cord-277665-ac8txr3h 81 8 used use VBN cord-277665-ac8txr3h 81 9 for for IN cord-277665-ac8txr3h 81 10 surface surface NN cord-277665-ac8txr3h 81 11 synthesis synthesis NN cord-277665-ac8txr3h 81 12 of of IN cord-277665-ac8txr3h 81 13 DNA dna NN cord-277665-ac8txr3h 81 14 and and CC cord-277665-ac8txr3h 81 15 protein protein NN cord-277665-ac8txr3h 81 16 immobilization immobilization NN cord-277665-ac8txr3h 81 17 . . . cord-277665-ac8txr3h 82 1 The the DT cord-277665-ac8txr3h 82 2 substantial substantial JJ cord-277665-ac8txr3h 82 3 increase increase NN cord-277665-ac8txr3h 82 4 in in IN cord-277665-ac8txr3h 82 5 the the DT cord-277665-ac8txr3h 82 6 number number NN cord-277665-ac8txr3h 82 7 of of IN cord-277665-ac8txr3h 82 8 surface surface NN cord-277665-ac8txr3h 82 9 C C NNP cord-277665-ac8txr3h 82 10 - - HYPH cord-277665-ac8txr3h 82 11 H H NNP cord-277665-ac8txr3h 82 12 groups group NNS cord-277665-ac8txr3h 82 13 was be VBD cord-277665-ac8txr3h 82 14 achieved achieve VBN cord-277665-ac8txr3h 82 15 by by IN cord-277665-ac8txr3h 82 16 the the DT cord-277665-ac8txr3h 82 17 gas gas NN cord-277665-ac8txr3h 82 18 treatment treatment NN cord-277665-ac8txr3h 82 19 of of IN cord-277665-ac8txr3h 82 20 ND ND NNP cord-277665-ac8txr3h 82 21 powder powder NN cord-277665-ac8txr3h 82 22 with with IN cord-277665-ac8txr3h 82 23 H H NNP cord-277665-ac8txr3h 82 24 2 2 CD cord-277665-ac8txr3h 82 25 , , , cord-277665-ac8txr3h 82 26 plasma plasma NN cord-277665-ac8txr3h 82 27 - - HYPH cord-277665-ac8txr3h 82 28 ionized ionize VBN cord-277665-ac8txr3h 82 29 hydrogen hydrogen NN cord-277665-ac8txr3h 82 30 , , , cord-277665-ac8txr3h 82 31 N n CD cord-277665-ac8txr3h 82 32 2 2 CD cord-277665-ac8txr3h 82 33 , , , cord-277665-ac8txr3h 82 34 methane methane NN cord-277665-ac8txr3h 82 35 and and CC cord-277665-ac8txr3h 82 36 air air NN cord-277665-ac8txr3h 82 37 , , , cord-277665-ac8txr3h 82 38 and and CC cord-277665-ac8txr3h 82 39 in in IN cord-277665-ac8txr3h 82 40 vacuum vacuum NN cord-277665-ac8txr3h 82 41 at at IN cord-277665-ac8txr3h 82 42 different different JJ cord-277665-ac8txr3h 82 43 temperatures temperature NNS cord-277665-ac8txr3h 82 44 ( ( -LRB- cord-277665-ac8txr3h 82 45 Jiang Jiang NNP cord-277665-ac8txr3h 82 46 et et FW cord-277665-ac8txr3h 82 47 al al NNP cord-277665-ac8txr3h 82 48 . . NNP cord-277665-ac8txr3h 82 49 , , , cord-277665-ac8txr3h 82 50 1996 1996 CD cord-277665-ac8txr3h 82 51 ) ) -RRB- cord-277665-ac8txr3h 82 52 . . . cord-277665-ac8txr3h 83 1 Surface surface NN cord-277665-ac8txr3h 83 2 decomposition decomposition NN cord-277665-ac8txr3h 83 3 , , , cord-277665-ac8txr3h 83 4 decarbonylation decarbonylation NN cord-277665-ac8txr3h 83 5 , , , cord-277665-ac8txr3h 83 6 and and CC cord-277665-ac8txr3h 83 7 decarboxylation decarboxylation NN cord-277665-ac8txr3h 83 8 were be VBD cord-277665-ac8txr3h 83 9 likely likely JJ cord-277665-ac8txr3h 83 10 to to TO cord-277665-ac8txr3h 83 11 be be VB cord-277665-ac8txr3h 83 12 the the DT cord-277665-ac8txr3h 83 13 main main JJ cord-277665-ac8txr3h 83 14 reactions reaction NNS cord-277665-ac8txr3h 83 15 . . . cord-277665-ac8txr3h 84 1 The the DT cord-277665-ac8txr3h 84 2 H h NN cord-277665-ac8txr3h 84 3 - - HYPH cord-277665-ac8txr3h 84 4 terminated terminate VBN cord-277665-ac8txr3h 84 5 ND ND NNP cord-277665-ac8txr3h 84 6 surfaces surface NNS cord-277665-ac8txr3h 84 7 can can MD cord-277665-ac8txr3h 84 8 be be VB cord-277665-ac8txr3h 84 9 further further RB cord-277665-ac8txr3h 84 10 reacted react VBN cord-277665-ac8txr3h 84 11 photochemically photochemically RB cord-277665-ac8txr3h 84 12 ( ( -LRB- cord-277665-ac8txr3h 84 13 λ λ NN cord-277665-ac8txr3h 84 14 = = SYM cord-277665-ac8txr3h 84 15 254 254 CD cord-277665-ac8txr3h 84 16 nm nm NN cord-277665-ac8txr3h 84 17 ) ) -RRB- cord-277665-ac8txr3h 84 18 with with IN cord-277665-ac8txr3h 84 19 longchain longchain NNP cord-277665-ac8txr3h 84 20 ω ω JJS cord-277665-ac8txr3h 84 21 - - HYPH cord-277665-ac8txr3h 84 22 unsaturated unsaturated JJ cord-277665-ac8txr3h 84 23 amines amine NNS cord-277665-ac8txr3h 84 24 to to TO cord-277665-ac8txr3h 84 25 produce produce VB cord-277665-ac8txr3h 84 26 a a DT cord-277665-ac8txr3h 84 27 homogeneous homogeneous JJ cord-277665-ac8txr3h 84 28 layer layer NN cord-277665-ac8txr3h 84 29 of of IN cord-277665-ac8txr3h 84 30 amine amine NN cord-277665-ac8txr3h 84 31 groups group NNS cord-277665-ac8txr3h 84 32 for for IN cord-277665-ac8txr3h 84 33 consequent consequent JJ cord-277665-ac8txr3h 84 34 DNA dna NN cord-277665-ac8txr3h 84 35 attachment attachment NN cord-277665-ac8txr3h 84 36 ( ( -LRB- cord-277665-ac8txr3h 84 37 Yang Yang NNP cord-277665-ac8txr3h 84 38 et et NNP cord-277665-ac8txr3h 84 39 al al NNP cord-277665-ac8txr3h 84 40 . . NNP cord-277665-ac8txr3h 84 41 , , , cord-277665-ac8txr3h 84 42 2002 2002 CD cord-277665-ac8txr3h 84 43 ) ) -RRB- cord-277665-ac8txr3h 84 44 . . . cord-277665-ac8txr3h 85 1 ND ND NNP cord-277665-ac8txr3h 85 2 purification purification NN cord-277665-ac8txr3h 85 3 and and CC cord-277665-ac8txr3h 85 4 functionalization functionalization NN cord-277665-ac8txr3h 85 5 can can MD cord-277665-ac8txr3h 85 6 also also RB cord-277665-ac8txr3h 85 7 be be VB cord-277665-ac8txr3h 85 8 carried carry VBN cord-277665-ac8txr3h 85 9 out out RP cord-277665-ac8txr3h 85 10 using use VBG cord-277665-ac8txr3h 85 11 gas gas NN cord-277665-ac8txr3h 85 12 and and CC cord-277665-ac8txr3h 85 13 vapor vapor NN cord-277665-ac8txr3h 85 14 reactive reactive JJ cord-277665-ac8txr3h 85 15 media medium NNS cord-277665-ac8txr3h 85 16 ( ( -LRB- cord-277665-ac8txr3h 85 17 Fig Fig NNP cord-277665-ac8txr3h 85 18 . . . cord-277665-ac8txr3h 85 19 15 15 CD cord-277665-ac8txr3h 85 20 .2 .2 CD cord-277665-ac8txr3h 85 21 ) ) -RRB- cord-277665-ac8txr3h 85 22 . . . cord-277665-ac8txr3h 86 1 The the DT cord-277665-ac8txr3h 86 2 chlorinated chlorinated JJ cord-277665-ac8txr3h 86 3 diamond diamond NN cord-277665-ac8txr3h 86 4 was be VBD cord-277665-ac8txr3h 86 5 pre pre JJ cord-277665-ac8txr3h 86 6 - - JJ cord-277665-ac8txr3h 86 7 pared pare VBN cord-277665-ac8txr3h 86 8 by by IN cord-277665-ac8txr3h 86 9 Sotowa Sotowa NNP cord-277665-ac8txr3h 86 10 et et NNP cord-277665-ac8txr3h 86 11 al al NNP cord-277665-ac8txr3h 86 12 . . . cord-277665-ac8txr3h 87 1 ( ( -LRB- cord-277665-ac8txr3h 87 2 2004 2004 CD cord-277665-ac8txr3h 87 3 ) ) -RRB- cord-277665-ac8txr3h 87 4 by by IN cord-277665-ac8txr3h 87 5 irradiating irradiate VBG cord-277665-ac8txr3h 87 6 hydrogenated hydrogenate VBN cord-277665-ac8txr3h 87 7 diamond diamond NN cord-277665-ac8txr3h 87 8 with with IN cord-277665-ac8txr3h 87 9 UV uv NN cord-277665-ac8txr3h 87 10 light light NN cord-277665-ac8txr3h 87 11 in in IN cord-277665-ac8txr3h 87 12 the the DT cord-277665-ac8txr3h 87 13 presence presence NN cord-277665-ac8txr3h 87 14 of of IN cord-277665-ac8txr3h 87 15 elemental elemental JJ cord-277665-ac8txr3h 87 16 chlorine chlorine NN cord-277665-ac8txr3h 87 17 . . . cord-277665-ac8txr3h 88 1 The the DT cord-277665-ac8txr3h 88 2 formation formation NN cord-277665-ac8txr3h 88 3 of of IN cord-277665-ac8txr3h 88 4 chlorinated chlorinated JJ cord-277665-ac8txr3h 88 5 diamond diamond NN cord-277665-ac8txr3h 88 6 was be VBD cord-277665-ac8txr3h 88 7 confirmed confirm VBN cord-277665-ac8txr3h 88 8 by by IN cord-277665-ac8txr3h 88 9 diffuse diffuse JJ cord-277665-ac8txr3h 88 10 reflectance reflectance NN cord-277665-ac8txr3h 88 11 FTIR FTIR NNP cord-277665-ac8txr3h 88 12 , , , cord-277665-ac8txr3h 88 13 which which WDT cord-277665-ac8txr3h 88 14 revealed reveal VBD cord-277665-ac8txr3h 88 15 a a DT cord-277665-ac8txr3h 88 16 strong strong JJ cord-277665-ac8txr3h 88 17 peak peak NN cord-277665-ac8txr3h 88 18 corresponding correspond VBG cord-277665-ac8txr3h 88 19 to to IN cord-277665-ac8txr3h 88 20 the the DT cord-277665-ac8txr3h 88 21 C C NNP cord-277665-ac8txr3h 88 22 - - HYPH cord-277665-ac8txr3h 88 23 Cl Cl NNP cord-277665-ac8txr3h 88 24 stretching stretch VBG cord-277665-ac8txr3h 88 25 . . . cord-277665-ac8txr3h 89 1 The the DT cord-277665-ac8txr3h 89 2 researchers researcher NNS cord-277665-ac8txr3h 89 3 then then RB cord-277665-ac8txr3h 89 4 treated treat VBD cord-277665-ac8txr3h 89 5 the the DT cord-277665-ac8txr3h 89 6 chlorinated chlorinated JJ cord-277665-ac8txr3h 89 7 diamond diamond NN cord-277665-ac8txr3h 89 8 surface surface NN cord-277665-ac8txr3h 89 9 further further RB cord-277665-ac8txr3h 89 10 with with IN cord-277665-ac8txr3h 89 11 ammonia ammonia NN cord-277665-ac8txr3h 89 12 and and CC cord-277665-ac8txr3h 89 13 found find VBD cord-277665-ac8txr3h 89 14 that that IN cord-277665-ac8txr3h 89 15 diamond diamond NN cord-277665-ac8txr3h 89 16 amination amination NN cord-277665-ac8txr3h 89 17 is be VBZ cord-277665-ac8txr3h 89 18 a a DT cord-277665-ac8txr3h 89 19 temperature temperature NN cord-277665-ac8txr3h 89 20 - - HYPH cord-277665-ac8txr3h 89 21 dependent dependent JJ cord-277665-ac8txr3h 89 22 process process NN cord-277665-ac8txr3h 89 23 and and CC cord-277665-ac8txr3h 89 24 results result NNS cord-277665-ac8txr3h 89 25 in in IN cord-277665-ac8txr3h 89 26 the the DT cord-277665-ac8txr3h 89 27 formation formation NN cord-277665-ac8txr3h 89 28 of of IN cord-277665-ac8txr3h 89 29 NH NH NNP cord-277665-ac8txr3h 89 30 4 4 CD cord-277665-ac8txr3h 89 31 + + SYM cord-277665-ac8txr3h 89 32 ; ; : cord-277665-ac8txr3h 89 33 C C NNP cord-277665-ac8txr3h 89 34 = = SYM cord-277665-ac8txr3h 89 35 N N NNP cord-277665-ac8txr3h 89 36 and and CC cord-277665-ac8txr3h 89 37 NH NH NNP cord-277665-ac8txr3h 89 38 2 2 CD cord-277665-ac8txr3h 89 39 ; ; : cord-277665-ac8txr3h 89 40 and and CC cord-277665-ac8txr3h 89 41 imines imine NNS cord-277665-ac8txr3h 89 42 at at IN cord-277665-ac8txr3h 89 43 room room NN cord-277665-ac8txr3h 89 44 temperature temperature NN cord-277665-ac8txr3h 89 45 , , , cord-277665-ac8txr3h 89 46 100 100 CD cord-277665-ac8txr3h 89 47 ° ° NN cord-277665-ac8txr3h 89 48 C c NN cord-277665-ac8txr3h 89 49 , , , cord-277665-ac8txr3h 89 50 and and CC cord-277665-ac8txr3h 89 51 200 200 CD cord-277665-ac8txr3h 89 52 ° ° NN cord-277665-ac8txr3h 89 53 C c NN cord-277665-ac8txr3h 89 54 , , , cord-277665-ac8txr3h 89 55 respectively respectively RB cord-277665-ac8txr3h 89 56 . . . cord-277665-ac8txr3h 90 1 High high JJ cord-277665-ac8txr3h 90 2 - - HYPH cord-277665-ac8txr3h 90 3 temperature temperature NN cord-277665-ac8txr3h 90 4 treatment treatment NN cord-277665-ac8txr3h 90 5 of of IN cord-277665-ac8txr3h 90 6 detonation detonation NN cord-277665-ac8txr3h 90 7 ND ND NNP cord-277665-ac8txr3h 90 8 with with IN cord-277665-ac8txr3h 90 9 hydrogen hydrogen NN cord-277665-ac8txr3h 90 10 , , , cord-277665-ac8txr3h 90 11 CCl CCl NNS cord-277665-ac8txr3h 90 12 4 4 CD cord-277665-ac8txr3h 90 13 , , , cord-277665-ac8txr3h 90 14 or or CC cord-277665-ac8txr3h 90 15 NH NH NNP cord-277665-ac8txr3h 90 16 3 3 CD cord-277665-ac8txr3h 90 17 has have VBZ cord-277665-ac8txr3h 90 18 been be VBN cord-277665-ac8txr3h 90 19 studied study VBN cord-277665-ac8txr3h 90 20 recently recently RB cord-277665-ac8txr3h 90 21 by by IN cord-277665-ac8txr3h 90 22 Spitsyn Spitsyn NNP cord-277665-ac8txr3h 90 23 et et FW cord-277665-ac8txr3h 90 24 al al NNP cord-277665-ac8txr3h 90 25 . . . cord-277665-ac8txr3h 91 1 ( ( -LRB- cord-277665-ac8txr3h 91 2 2005 2005 CD cord-277665-ac8txr3h 91 3 ) ) -RRB- cord-277665-ac8txr3h 91 4 . . . cord-277665-ac8txr3h 92 1 ND ND NNP cord-277665-ac8txr3h 92 2 , , , cord-277665-ac8txr3h 92 3 which which WDT cord-277665-ac8txr3h 92 4 was be VBD cord-277665-ac8txr3h 92 5 annealed anneal VBN cord-277665-ac8txr3h 92 6 in in IN cord-277665-ac8txr3h 92 7 hydrogen hydrogen NN cord-277665-ac8txr3h 92 8 flow flow NN cord-277665-ac8txr3h 92 9 at at IN cord-277665-ac8txr3h 92 10 850 850 CD cord-277665-ac8txr3h 92 11 ° ° NN cord-277665-ac8txr3h 92 12 C c NN cord-277665-ac8txr3h 92 13 for for IN cord-277665-ac8txr3h 92 14 5 5 CD cord-277665-ac8txr3h 92 15 h h NN cord-277665-ac8txr3h 92 16 , , , cord-277665-ac8txr3h 92 17 possessed possess VBD cord-277665-ac8txr3h 92 18 about about IN cord-277665-ac8txr3h 92 19 1000 1000 CD cord-277665-ac8txr3h 92 20 cal cal NN cord-277665-ac8txr3h 92 21 g g NNP cord-277665-ac8txr3h 92 22 −1 −1 NNP cord-277665-ac8txr3h 92 23 lower low JJR cord-277665-ac8txr3h 92 24 combustion combustion NN cord-277665-ac8txr3h 92 25 heat heat NN cord-277665-ac8txr3h 92 26 than than IN cord-277665-ac8txr3h 92 27 non non JJ cord-277665-ac8txr3h 92 28 - - JJ cord-277665-ac8txr3h 92 29 modified modified JJ cord-277665-ac8txr3h 92 30 ND ND NNP cord-277665-ac8txr3h 92 31 powder powder NN cord-277665-ac8txr3h 92 32 . . . cord-277665-ac8txr3h 93 1 Moreover moreover RB cord-277665-ac8txr3h 93 2 , , , cord-277665-ac8txr3h 93 3 the the DT cord-277665-ac8txr3h 93 4 initial initial JJ cord-277665-ac8txr3h 93 5 dangling dangle VBG cord-277665-ac8txr3h 93 6 bonds bond NNS cord-277665-ac8txr3h 93 7 density density NN cord-277665-ac8txr3h 93 8 of of IN cord-277665-ac8txr3h 93 9 ∼1.16 ∼1.16 NNP cord-277665-ac8txr3h 93 10 × × NNP cord-277665-ac8txr3h 93 11 10 10 CD cord-277665-ac8txr3h 93 12 20 20 CD cord-277665-ac8txr3h 93 13 spin spin NN cord-277665-ac8txr3h 93 14 / / SYM cord-277665-ac8txr3h 93 15 cm cm NN cord-277665-ac8txr3h 93 16 3 3 CD cord-277665-ac8txr3h 93 17 was be VBD cord-277665-ac8txr3h 93 18 reduced reduce VBN cord-277665-ac8txr3h 93 19 1.5 1.5 CD cord-277665-ac8txr3h 93 20 times time NNS cord-277665-ac8txr3h 93 21 after after IN cord-277665-ac8txr3h 93 22 the the DT cord-277665-ac8txr3h 93 23 treatment treatment NN cord-277665-ac8txr3h 93 24 with with IN cord-277665-ac8txr3h 93 25 hydrogen hydrogen NN cord-277665-ac8txr3h 93 26 . . . cord-277665-ac8txr3h 94 1 After after IN cord-277665-ac8txr3h 94 2 treatment treatment NN cord-277665-ac8txr3h 94 3 in in IN cord-277665-ac8txr3h 94 4 a a DT cord-277665-ac8txr3h 94 5 CCl ccl NN cord-277665-ac8txr3h 94 6 4 4 CD cord-277665-ac8txr3h 94 7 /Ar /ar NN cord-277665-ac8txr3h 94 8 mixture mixture NN cord-277665-ac8txr3h 94 9 at at IN cord-277665-ac8txr3h 94 10 450 450 CD cord-277665-ac8txr3h 94 11 ° ° NN cord-277665-ac8txr3h 94 12 C c NN cord-277665-ac8txr3h 94 13 for for IN cord-277665-ac8txr3h 94 14 0.5 0.5 CD cord-277665-ac8txr3h 94 15 - - SYM cord-277665-ac8txr3h 94 16 3 3 CD cord-277665-ac8txr3h 94 17 h h NN cord-277665-ac8txr3h 94 18 the the DT cord-277665-ac8txr3h 94 19 hydrophilicity hydrophilicity NN cord-277665-ac8txr3h 94 20 of of IN cord-277665-ac8txr3h 94 21 ND ND NNP cord-277665-ac8txr3h 94 22 was be VBD cord-277665-ac8txr3h 94 23 changed change VBN cord-277665-ac8txr3h 94 24 significantly significantly RB cord-277665-ac8txr3h 94 25 : : : cord-277665-ac8txr3h 94 26 the the DT cord-277665-ac8txr3h 94 27 atmospheric atmospheric JJ cord-277665-ac8txr3h 94 28 water water NN cord-277665-ac8txr3h 94 29 vapor vapor NN cord-277665-ac8txr3h 94 30 readsorbance readsorbance NNP cord-277665-ac8txr3h 94 31 was be VBD cord-277665-ac8txr3h 94 32 at at IN cord-277665-ac8txr3h 94 33 least least RBS cord-277665-ac8txr3h 94 34 20 20 CD cord-277665-ac8txr3h 94 35 times time NNS cord-277665-ac8txr3h 94 36 lower low JJR cord-277665-ac8txr3h 94 37 than than IN cord-277665-ac8txr3h 94 38 in in IN cord-277665-ac8txr3h 94 39 the the DT cord-277665-ac8txr3h 94 40 ND ND NNP cord-277665-ac8txr3h 94 41 samples sample NNS cord-277665-ac8txr3h 94 42 treated treat VBN cord-277665-ac8txr3h 94 43 in in IN cord-277665-ac8txr3h 94 44 pure pure JJ cord-277665-ac8txr3h 94 45 Ar Ar NNP cord-277665-ac8txr3h 94 46 . . . cord-277665-ac8txr3h 95 1 After after IN cord-277665-ac8txr3h 95 2 treatment treatment NN cord-277665-ac8txr3h 95 3 in in IN cord-277665-ac8txr3h 95 4 a a DT cord-277665-ac8txr3h 95 5 NH NH NNP cord-277665-ac8txr3h 95 6 3 3 CD cord-277665-ac8txr3h 95 7 flow flow NN cord-277665-ac8txr3h 95 8 at at IN cord-277665-ac8txr3h 95 9 600 600 CD cord-277665-ac8txr3h 95 10 ° ° NN cord-277665-ac8txr3h 95 11 C c NN cord-277665-ac8txr3h 95 12 for for IN cord-277665-ac8txr3h 95 13 70 70 CD cord-277665-ac8txr3h 95 14 min min NN cord-277665-ac8txr3h 95 15 the the DT cord-277665-ac8txr3h 95 16 number number NN cord-277665-ac8txr3h 95 17 of of IN cord-277665-ac8txr3h 95 18 oxygen oxygen NN cord-277665-ac8txr3h 95 19 - - HYPH cord-277665-ac8txr3h 95 20 containing contain VBG cord-277665-ac8txr3h 95 21 groups group NNS cord-277665-ac8txr3h 95 22 had have VBD cord-277665-ac8txr3h 95 23 decreased decrease VBN cord-277665-ac8txr3h 95 24 and and CC cord-277665-ac8txr3h 95 25 atmospheric atmospheric JJ cord-277665-ac8txr3h 95 26 water water NN cord-277665-ac8txr3h 95 27 vapor vapor NN cord-277665-ac8txr3h 95 28 readsorbance readsorbance NNP cord-277665-ac8txr3h 95 29 was be VBD cord-277665-ac8txr3h 95 30 four four CD cord-277665-ac8txr3h 95 31 times time NNS cord-277665-ac8txr3h 95 32 lower low JJR cord-277665-ac8txr3h 95 33 than than IN cord-277665-ac8txr3h 95 34 in in IN cord-277665-ac8txr3h 95 35 the the DT cord-277665-ac8txr3h 95 36 initial initial JJ cord-277665-ac8txr3h 95 37 ND ND NNP cord-277665-ac8txr3h 95 38 samples sample NNS cord-277665-ac8txr3h 95 39 . . . cord-277665-ac8txr3h 96 1 A a DT cord-277665-ac8txr3h 96 2 number number NN cord-277665-ac8txr3h 96 3 of of IN cord-277665-ac8txr3h 96 4 characterization characterization NN cord-277665-ac8txr3h 96 5 methods method NNS cord-277665-ac8txr3h 96 6 such such JJ cord-277665-ac8txr3h 96 7 as as IN cord-277665-ac8txr3h 96 8 chemical chemical NN cord-277665-ac8txr3h 96 9 analysis analysis NN cord-277665-ac8txr3h 96 10 , , , cord-277665-ac8txr3h 96 11 Raman Raman NNP cord-277665-ac8txr3h 96 12 , , , cord-277665-ac8txr3h 96 13 FTIR FTIR NNP cord-277665-ac8txr3h 96 14 , , , cord-277665-ac8txr3h 96 15 electron electron NN cord-277665-ac8txr3h 96 16 spin spin NN cord-277665-ac8txr3h 96 17 resonance resonance NN cord-277665-ac8txr3h 96 18 ( ( -LRB- cord-277665-ac8txr3h 96 19 ESR ESR NNP cord-277665-ac8txr3h 96 20 ) ) -RRB- cord-277665-ac8txr3h 96 21 , , , cord-277665-ac8txr3h 96 22 and and CC cord-277665-ac8txr3h 96 23 chromatomass chromatomass NNP cord-277665-ac8txr3h 96 24 spectrometry spectrometry NNP cord-277665-ac8txr3h 96 25 confirmed confirm VBD cord-277665-ac8txr3h 96 26 the the DT cord-277665-ac8txr3h 96 27 possibility possibility NN cord-277665-ac8txr3h 96 28 of of IN cord-277665-ac8txr3h 96 29 extensive extensive JJ cord-277665-ac8txr3h 96 30 modification modification NN cord-277665-ac8txr3h 96 31 and and CC cord-277665-ac8txr3h 96 32 controlled control VBN cord-277665-ac8txr3h 96 33 functionalization functionalization NN cord-277665-ac8txr3h 96 34 of of IN cord-277665-ac8txr3h 96 35 the the DT cord-277665-ac8txr3h 96 36 ND ND NNP cord-277665-ac8txr3h 96 37 using use VBG cord-277665-ac8txr3h 96 38 gas gas NN cord-277665-ac8txr3h 96 39 treatment treatment NN cord-277665-ac8txr3h 96 40 ( ( -LRB- cord-277665-ac8txr3h 96 41 in in IN cord-277665-ac8txr3h 96 42 terms term NNS cord-277665-ac8txr3h 96 43 of of IN cord-277665-ac8txr3h 96 44 hydrophilic/ hydrophilic/ CD cord-277665-ac8txr3h 96 45 hydrophobic hydrophobic JJ cord-277665-ac8txr3h 96 46 or or CC cord-277665-ac8txr3h 96 47 acidic acidic JJ cord-277665-ac8txr3h 96 48 / / SYM cord-277665-ac8txr3h 96 49 basic basic JJ cord-277665-ac8txr3h 96 50 ND ND NNP cord-277665-ac8txr3h 96 51 termination termination NN cord-277665-ac8txr3h 96 52 ) ) -RRB- cord-277665-ac8txr3h 97 1 ( ( -LRB- cord-277665-ac8txr3h 97 2 Spitsyn Spitsyn NNP cord-277665-ac8txr3h 97 3 et et FW cord-277665-ac8txr3h 97 4 al al NNP cord-277665-ac8txr3h 97 5 . . NNP cord-277665-ac8txr3h 97 6 , , , cord-277665-ac8txr3h 97 7 2005 2005 CD cord-277665-ac8txr3h 97 8 ) ) -RRB- cord-277665-ac8txr3h 97 9 . . . cord-277665-ac8txr3h 98 1 This this DT cord-277665-ac8txr3h 98 2 prevents prevent VBZ cord-277665-ac8txr3h 98 3 agglomeration agglomeration NN cord-277665-ac8txr3h 98 4 of of IN cord-277665-ac8txr3h 98 5 hydrophilic hydrophilic JJ cord-277665-ac8txr3h 98 6 and and CC cord-277665-ac8txr3h 98 7 hydrophobic hydrophobic JJ cord-277665-ac8txr3h 98 8 detonation detonation NN cord-277665-ac8txr3h 98 9 ND ND NNP cord-277665-ac8txr3h 98 10 in in IN cord-277665-ac8txr3h 98 11 polar polar JJ cord-277665-ac8txr3h 98 12 and and CC cord-277665-ac8txr3h 98 13 non non JJ cord-277665-ac8txr3h 98 14 - - JJ cord-277665-ac8txr3h 98 15 polar polar JJ cord-277665-ac8txr3h 98 16 solvents solvent NNS cord-277665-ac8txr3h 98 17 , , , cord-277665-ac8txr3h 98 18 correspondingly correspondingly RB cord-277665-ac8txr3h 98 19 . . . cord-277665-ac8txr3h 99 1 Fluorination fluorination NN cord-277665-ac8txr3h 99 2 is be VBZ cord-277665-ac8txr3h 99 3 another another DT cord-277665-ac8txr3h 99 4 efficient efficient JJ cord-277665-ac8txr3h 99 5 method method NN cord-277665-ac8txr3h 99 6 for for IN cord-277665-ac8txr3h 99 7 ND ND NNP cord-277665-ac8txr3h 99 8 chemical chemical NN cord-277665-ac8txr3h 99 9 modification modification NN cord-277665-ac8txr3h 99 10 that that WDT cord-277665-ac8txr3h 99 11 enables enable VBZ cord-277665-ac8txr3h 99 12 a a DT cord-277665-ac8txr3h 99 13 variety variety NN cord-277665-ac8txr3h 99 14 of of IN cord-277665-ac8txr3h 99 15 applications application NNS cord-277665-ac8txr3h 99 16 in in IN cord-277665-ac8txr3h 99 17 engineering engineering NN cord-277665-ac8txr3h 99 18 and and CC cord-277665-ac8txr3h 99 19 biological biological JJ cord-277665-ac8txr3h 99 20 sciences science NNS cord-277665-ac8txr3h 99 21 ( ( -LRB- cord-277665-ac8txr3h 99 22 Fig Fig NNP cord-277665-ac8txr3h 99 23 . . . cord-277665-ac8txr3h 99 24 15 15 CD cord-277665-ac8txr3h 99 25 .2 .2 CD cord-277665-ac8txr3h 99 26 ) ) -RRB- cord-277665-ac8txr3h 99 27 . . . cord-277665-ac8txr3h 100 1 Treatment treatment NN cord-277665-ac8txr3h 100 2 of of IN cord-277665-ac8txr3h 100 3 detonation detonation NN cord-277665-ac8txr3h 100 4 UNCD UNCD NNP cord-277665-ac8txr3h 100 5 powder powder NN cord-277665-ac8txr3h 100 6 ( ( -LRB- cord-277665-ac8txr3h 100 7 1 1 CD cord-277665-ac8txr3h 100 8 - - SYM cord-277665-ac8txr3h 100 9 2 2 CD cord-277665-ac8txr3h 100 10 µm µm NN cord-277665-ac8txr3h 100 11 sized sized JJ cord-277665-ac8txr3h 100 12 particles particle NNS cord-277665-ac8txr3h 100 13 composed compose VBN cord-277665-ac8txr3h 100 14 of of IN cord-277665-ac8txr3h 100 15 3.5 3.5 CD cord-277665-ac8txr3h 100 16 - - SYM cord-277665-ac8txr3h 100 17 6.5 6.5 CD cord-277665-ac8txr3h 100 18 nm nm NN cord-277665-ac8txr3h 100 19 diamond diamond NN cord-277665-ac8txr3h 100 20 nanocrystals nanocrystal NNS cord-277665-ac8txr3h 100 21 , , , cord-277665-ac8txr3h 100 22 > > XX cord-277665-ac8txr3h 100 23 97 97 CD cord-277665-ac8txr3h 100 24 % % NN cord-277665-ac8txr3h 100 25 purity purity NN cord-277665-ac8txr3h 100 26 ) ) -RRB- cord-277665-ac8txr3h 100 27 with with IN cord-277665-ac8txr3h 100 28 a a DT cord-277665-ac8txr3h 100 29 F F NNP cord-277665-ac8txr3h 100 30 2 2 CD cord-277665-ac8txr3h 100 31 /H /h SYM cord-277665-ac8txr3h 100 32 2 2 CD cord-277665-ac8txr3h 100 33 mixture mixture NN cord-277665-ac8txr3h 100 34 at at IN cord-277665-ac8txr3h 100 35 150 150 CD cord-277665-ac8txr3h 100 36 - - SYM cord-277665-ac8txr3h 100 37 470 470 CD cord-277665-ac8txr3h 100 38 ° ° NN cord-277665-ac8txr3h 100 39 C C NNP cord-277665-ac8txr3h 100 40 resulted result VBD cord-277665-ac8txr3h 100 41 in in IN cord-277665-ac8txr3h 100 42 the the DT cord-277665-ac8txr3h 100 43 formation formation NN cord-277665-ac8txr3h 100 44 of of IN cord-277665-ac8txr3h 100 45 fluorinated fluorinated JJ cord-277665-ac8txr3h 100 46 NDs nd NNS cord-277665-ac8txr3h 100 47 with with IN cord-277665-ac8txr3h 100 48 8.6 8.6 CD cord-277665-ac8txr3h 100 49 at.% at.% NNP cord-277665-ac8txr3h 100 50 fluorine fluorine NN cord-277665-ac8txr3h 100 51 . . . cord-277665-ac8txr3h 101 1 The the DT cord-277665-ac8txr3h 101 2 fluorinated fluorinated JJ cord-277665-ac8txr3h 101 3 ND ND NNP cord-277665-ac8txr3h 101 4 material material NN cord-277665-ac8txr3h 101 5 was be VBD cord-277665-ac8txr3h 101 6 then then RB cord-277665-ac8txr3h 101 7 used use VBN cord-277665-ac8txr3h 101 8 as as IN cord-277665-ac8txr3h 101 9 a a DT cord-277665-ac8txr3h 101 10 precursor precursor NN cord-277665-ac8txr3h 101 11 for for IN cord-277665-ac8txr3h 101 12 preparation preparation NN cord-277665-ac8txr3h 101 13 of of IN cord-277665-ac8txr3h 101 14 alkyl- alkyl- NN cord-277665-ac8txr3h 101 15 , , , cord-277665-ac8txr3h 101 16 amino- amino- NN cord-277665-ac8txr3h 101 17 , , , cord-277665-ac8txr3h 101 18 and and CC cord-277665-ac8txr3h 101 19 amino amino NN cord-277665-ac8txr3h 101 20 acid acid NN cord-277665-ac8txr3h 101 21 - - HYPH cord-277665-ac8txr3h 101 22 functionalized functionalize VBN cord-277665-ac8txr3h 101 23 NDs nd NNS cord-277665-ac8txr3h 101 24 that that WDT cord-277665-ac8txr3h 101 25 showed show VBD cord-277665-ac8txr3h 101 26 an an DT cord-277665-ac8txr3h 101 27 increased increase VBN cord-277665-ac8txr3h 101 28 solubility solubility NN cord-277665-ac8txr3h 101 29 in in IN cord-277665-ac8txr3h 101 30 polar polar JJ cord-277665-ac8txr3h 101 31 solvents solvent NNS cord-277665-ac8txr3h 101 32 and and CC cord-277665-ac8txr3h 101 33 reduced reduce VBN cord-277665-ac8txr3h 101 34 particle particle NN cord-277665-ac8txr3h 101 35 agglomeration agglomeration NN cord-277665-ac8txr3h 101 36 . . . cord-277665-ac8txr3h 102 1 Application application NN cord-277665-ac8txr3h 102 2 of of IN cord-277665-ac8txr3h 102 3 fluorinated fluorinated JJ cord-277665-ac8txr3h 102 4 ND ND NNP cord-277665-ac8txr3h 102 5 has have VBZ cord-277665-ac8txr3h 102 6 been be VBN cord-277665-ac8txr3h 102 7 found find VBN cord-277665-ac8txr3h 102 8 in in IN cord-277665-ac8txr3h 102 9 cost cost NN cord-277665-ac8txr3h 102 10 - - HYPH cord-277665-ac8txr3h 102 11 effective effective JJ cord-277665-ac8txr3h 102 12 synthesis synthesis NN cord-277665-ac8txr3h 102 13 of of IN cord-277665-ac8txr3h 102 14 diamond diamond NN cord-277665-ac8txr3h 102 15 coatings coating NNS cord-277665-ac8txr3h 102 16 covalently covalently RB cord-277665-ac8txr3h 102 17 bonded bond VBN cord-277665-ac8txr3h 102 18 to to IN cord-277665-ac8txr3h 102 19 glass glass NN cord-277665-ac8txr3h 102 20 surfaces surface NNS cord-277665-ac8txr3h 102 21 ( ( -LRB- cord-277665-ac8txr3h 102 22 Liu Liu NNP cord-277665-ac8txr3h 102 23 et et NNP cord-277665-ac8txr3h 102 24 al al NNP cord-277665-ac8txr3h 102 25 . . NNP cord-277665-ac8txr3h 102 26 , , , cord-277665-ac8txr3h 102 27 2005 2005 CD cord-277665-ac8txr3h 102 28 ) ) -RRB- cord-277665-ac8txr3h 102 29 . . . cord-277665-ac8txr3h 103 1 Before before IN cord-277665-ac8txr3h 103 2 that that DT cord-277665-ac8txr3h 103 3 the the DT cord-277665-ac8txr3h 103 4 production production NN cord-277665-ac8txr3h 103 5 of of IN cord-277665-ac8txr3h 103 6 diamond diamond NN cord-277665-ac8txr3h 103 7 thin thin JJ cord-277665-ac8txr3h 103 8 films film NNS cord-277665-ac8txr3h 103 9 could could MD cord-277665-ac8txr3h 103 10 only only RB cord-277665-ac8txr3h 103 11 be be VB cord-277665-ac8txr3h 103 12 achieved achieve VBN cord-277665-ac8txr3h 103 13 by by IN cord-277665-ac8txr3h 103 14 chemical chemical JJ cord-277665-ac8txr3h 103 15 vapor vapor NN cord-277665-ac8txr3h 103 16 deposition deposition NN cord-277665-ac8txr3h 103 17 that that WDT cord-277665-ac8txr3h 103 18 requires require VBZ cord-277665-ac8txr3h 103 19 heating heating NN cord-277665-ac8txr3h 103 20 to to IN cord-277665-ac8txr3h 103 21 1000 1000 CD cord-277665-ac8txr3h 103 22 ° ° NN cord-277665-ac8txr3h 103 23 C c NN cord-277665-ac8txr3h 103 24 . . . cord-277665-ac8txr3h 104 1 Liu Liu NNP cord-277665-ac8txr3h 104 2 et et NNP cord-277665-ac8txr3h 104 3 al al NNP cord-277665-ac8txr3h 104 4 . . . cord-277665-ac8txr3h 105 1 ( ( -LRB- cord-277665-ac8txr3h 105 2 2005 2005 CD cord-277665-ac8txr3h 105 3 ) ) -RRB- cord-277665-ac8txr3h 105 4 applied apply VBD cord-277665-ac8txr3h 105 5 a a DT cord-277665-ac8txr3h 105 6 silane silane NN cord-277665-ac8txr3h 105 7 coupling coupling NN cord-277665-ac8txr3h 105 8 agent agent NN cord-277665-ac8txr3h 105 9 , , , cord-277665-ac8txr3h 105 10 3-aminopropyltriethoxysilane 3-aminopropyltriethoxysilane CD cord-277665-ac8txr3h 105 11 , , , cord-277665-ac8txr3h 105 12 to to TO cord-277665-ac8txr3h 105 13 attach attach VB cord-277665-ac8txr3h 105 14 fluoro fluoro NN cord-277665-ac8txr3h 105 15 - - HYPH cord-277665-ac8txr3h 105 16 ND ND NNP cord-277665-ac8txr3h 105 17 to to IN cord-277665-ac8txr3h 105 18 the the DT cord-277665-ac8txr3h 105 19 glass glass NN cord-277665-ac8txr3h 105 20 slide slide NN cord-277665-ac8txr3h 105 21 surface surface NN cord-277665-ac8txr3h 105 22 , , , cord-277665-ac8txr3h 105 23 which which WDT cord-277665-ac8txr3h 105 24 was be VBD cord-277665-ac8txr3h 105 25 preliminary preliminary JJ cord-277665-ac8txr3h 105 26 func func NN cord-277665-ac8txr3h 105 27 - - HYPH cord-277665-ac8txr3h 105 28 tionalized tionalize VBN cord-277665-ac8txr3h 105 29 with with IN cord-277665-ac8txr3h 105 30 terminal terminal JJ cord-277665-ac8txr3h 105 31 amino amino NN cord-277665-ac8txr3h 105 32 groups group NNS cord-277665-ac8txr3h 105 33 . . . cord-277665-ac8txr3h 106 1 Using use VBG cord-277665-ac8txr3h 106 2 atomic atomic JJ cord-277665-ac8txr3h 106 3 force force NN cord-277665-ac8txr3h 106 4 microscopy microscopy NN cord-277665-ac8txr3h 106 5 ( ( -LRB- cord-277665-ac8txr3h 106 6 AFM AFM NNP cord-277665-ac8txr3h 106 7 ) ) -RRB- cord-277665-ac8txr3h 106 8 , , , cord-277665-ac8txr3h 106 9 SEM SEM NNP cord-277665-ac8txr3h 106 10 , , , cord-277665-ac8txr3h 106 11 and and CC cord-277665-ac8txr3h 106 12 X x NN cord-277665-ac8txr3h 106 13 - - NN cord-277665-ac8txr3h 106 14 ray ray NN cord-277665-ac8txr3h 106 15 photoelectron photoelectron NN cord-277665-ac8txr3h 106 16 spectroscopy spectroscopy NN cord-277665-ac8txr3h 106 17 ( ( -LRB- cord-277665-ac8txr3h 107 1 XPS XPS NNP cord-277665-ac8txr3h 107 2 ) ) -RRB- cord-277665-ac8txr3h 107 3 analysis analysis NN cord-277665-ac8txr3h 108 1 it -PRON- PRP cord-277665-ac8txr3h 108 2 was be VBD cord-277665-ac8txr3h 108 3 established establish VBN cord-277665-ac8txr3h 108 4 that that IN cord-277665-ac8txr3h 108 5 surface surface NN cord-277665-ac8txr3h 108 6 - - HYPH cord-277665-ac8txr3h 108 7 bonded bond VBN cord-277665-ac8txr3h 108 8 fluoro fluoro NN cord-277665-ac8txr3h 108 9 - - HYPH cord-277665-ac8txr3h 108 10 ND ND NNP cord-277665-ac8txr3h 108 11 particles particle NNS cord-277665-ac8txr3h 108 12 were be VBD cord-277665-ac8txr3h 108 13 closely closely RB cord-277665-ac8txr3h 108 14 packed pack VBN cord-277665-ac8txr3h 108 15 and and CC cord-277665-ac8txr3h 108 16 had have VBD cord-277665-ac8txr3h 108 17 an an DT cord-277665-ac8txr3h 108 18 average average JJ cord-277665-ac8txr3h 108 19 size size NN cord-277665-ac8txr3h 108 20 of of IN cord-277665-ac8txr3h 108 21 10 10 CD cord-277665-ac8txr3h 108 22 - - SYM cord-277665-ac8txr3h 108 23 40 40 CD cord-277665-ac8txr3h 108 24 nm nm NN cord-277665-ac8txr3h 108 25 . . . cord-277665-ac8txr3h 109 1 The the DT cord-277665-ac8txr3h 109 2 fluoro fluoro NN cord-277665-ac8txr3h 109 3 - - HYPH cord-277665-ac8txr3h 109 4 ND ND NNP cord-277665-ac8txr3h 109 5 , , , cord-277665-ac8txr3h 109 6 which which WDT cord-277665-ac8txr3h 109 7 is be VBZ cord-277665-ac8txr3h 109 8 covalently covalently RB cord-277665-ac8txr3h 109 9 attached attach VBN cord-277665-ac8txr3h 109 10 to to IN cord-277665-ac8txr3h 109 11 the the DT cord-277665-ac8txr3h 109 12 surface surface NN cord-277665-ac8txr3h 109 13 of of IN cord-277665-ac8txr3h 109 14 the the DT cord-277665-ac8txr3h 109 15 glass glass NN cord-277665-ac8txr3h 109 16 slide slide NN cord-277665-ac8txr3h 109 17 , , , cord-277665-ac8txr3h 109 18 can can MD cord-277665-ac8txr3h 109 19 be be VB cord-277665-ac8txr3h 109 20 further further RB cord-277665-ac8txr3h 109 21 modified modify VBN cord-277665-ac8txr3h 109 22 by by IN cord-277665-ac8txr3h 109 23 chemical chemical JJ cord-277665-ac8txr3h 109 24 substitution substitution NN cord-277665-ac8txr3h 109 25 of of IN cord-277665-ac8txr3h 109 26 residual residual JJ cord-277665-ac8txr3h 109 27 fluorine fluorine NN cord-277665-ac8txr3h 109 28 . . . cord-277665-ac8txr3h 110 1 Nanoparticles nanoparticle NNS cord-277665-ac8txr3h 110 2 are be VBP cord-277665-ac8txr3h 110 3 valuable valuable JJ cord-277665-ac8txr3h 110 4 platforms platform NNS cord-277665-ac8txr3h 110 5 in in IN cord-277665-ac8txr3h 110 6 controlled control VBN cord-277665-ac8txr3h 110 7 drug drug NN cord-277665-ac8txr3h 110 8 delivery delivery NN cord-277665-ac8txr3h 110 9 and and CC cord-277665-ac8txr3h 110 10 can can MD cord-277665-ac8txr3h 110 11 be be VB cord-277665-ac8txr3h 110 12 administered administer VBN cord-277665-ac8txr3h 110 13 via via IN cord-277665-ac8txr3h 110 14 most most JJS cord-277665-ac8txr3h 110 15 routes route NNS cord-277665-ac8txr3h 110 16 to to TO cord-277665-ac8txr3h 110 17 carry carry VB cord-277665-ac8txr3h 110 18 various various JJ cord-277665-ac8txr3h 110 19 therapeutics therapeutic NNS cord-277665-ac8txr3h 110 20 , , , cord-277665-ac8txr3h 110 21 anticancer anticancer JJ cord-277665-ac8txr3h 110 22 , , , cord-277665-ac8txr3h 110 23 antiviral antiviral JJ cord-277665-ac8txr3h 110 24 , , , cord-277665-ac8txr3h 110 25 antibacterial antibacterial JJ cord-277665-ac8txr3h 110 26 , , , cord-277665-ac8txr3h 110 27 and and CC cord-277665-ac8txr3h 110 28 antihypertensive antihypertensive JJ cord-277665-ac8txr3h 110 29 agents agent NNS cord-277665-ac8txr3h 110 30 , , , cord-277665-ac8txr3h 110 31 immunomodulators immunomodulator NNS cord-277665-ac8txr3h 110 32 , , , cord-277665-ac8txr3h 110 33 hormones hormone NNS cord-277665-ac8txr3h 110 34 , , , cord-277665-ac8txr3h 110 35 antibodies antibody NNS cord-277665-ac8txr3h 110 36 , , , cord-277665-ac8txr3h 110 37 proteins protein NNS cord-277665-ac8txr3h 110 38 , , , cord-277665-ac8txr3h 110 39 peptides peptide NNS cord-277665-ac8txr3h 110 40 , , , cord-277665-ac8txr3h 110 41 and and CC cord-277665-ac8txr3h 110 42 nucleic nucleic JJ cord-277665-ac8txr3h 110 43 acids acid NNS cord-277665-ac8txr3h 110 44 to to IN cord-277665-ac8txr3h 110 45 isolated isolate VBN cord-277665-ac8txr3h 110 46 cells cell NNS cord-277665-ac8txr3h 110 47 , , , cord-277665-ac8txr3h 110 48 tissues tissue NNS cord-277665-ac8txr3h 110 49 , , , cord-277665-ac8txr3h 110 50 and and CC cord-277665-ac8txr3h 110 51 organs organ NNS cord-277665-ac8txr3h 110 52 ( ( -LRB- cord-277665-ac8txr3h 110 53 Bala Bala NNP cord-277665-ac8txr3h 110 54 et et NNP cord-277665-ac8txr3h 110 55 al al NNP cord-277665-ac8txr3h 110 56 . . NNP cord-277665-ac8txr3h 110 57 , , , cord-277665-ac8txr3h 110 58 2004 2004 CD cord-277665-ac8txr3h 110 59 ; ; : cord-277665-ac8txr3h 110 60 Ozkan Ozkan NNP cord-277665-ac8txr3h 110 61 , , , cord-277665-ac8txr3h 110 62 2004 2004 CD cord-277665-ac8txr3h 110 63 ) ) -RRB- cord-277665-ac8txr3h 110 64 . . . cord-277665-ac8txr3h 111 1 Successful successful JJ cord-277665-ac8txr3h 111 2 design design NN cord-277665-ac8txr3h 111 3 of of IN cord-277665-ac8txr3h 111 4 highly highly RB cord-277665-ac8txr3h 111 5 efficient efficient JJ cord-277665-ac8txr3h 111 6 drug drug NN cord-277665-ac8txr3h 111 7 delivery delivery NN cord-277665-ac8txr3h 111 8 systems system NNS cord-277665-ac8txr3h 111 9 may may MD cord-277665-ac8txr3h 111 10 solve solve VB cord-277665-ac8txr3h 111 11 many many JJ cord-277665-ac8txr3h 111 12 problems problem NNS cord-277665-ac8txr3h 111 13 faced face VBN cord-277665-ac8txr3h 111 14 by by IN cord-277665-ac8txr3h 111 15 present present JJ cord-277665-ac8txr3h 111 16 - - HYPH cord-277665-ac8txr3h 111 17 day day NN cord-277665-ac8txr3h 111 18 medical medical JJ cord-277665-ac8txr3h 111 19 sciences science NNS cord-277665-ac8txr3h 111 20 . . . cord-277665-ac8txr3h 112 1 In in IN cord-277665-ac8txr3h 112 2 gene gene NN cord-277665-ac8txr3h 112 3 therapy therapy NN cord-277665-ac8txr3h 112 4 , , , cord-277665-ac8txr3h 112 5 genes gene NNS cord-277665-ac8txr3h 112 6 are be VBP cord-277665-ac8txr3h 112 7 delivered deliver VBN cord-277665-ac8txr3h 112 8 to to IN cord-277665-ac8txr3h 112 9 the the DT cord-277665-ac8txr3h 112 10 cell cell NN cord-277665-ac8txr3h 112 11 nucleus nucleus NN cord-277665-ac8txr3h 112 12 allowing allow VBG cord-277665-ac8txr3h 112 13 cells cell NNS cord-277665-ac8txr3h 112 14 to to TO cord-277665-ac8txr3h 112 15 produce produce VB cord-277665-ac8txr3h 112 16 therapeutic therapeutic JJ cord-277665-ac8txr3h 112 17 proteins protein NNS cord-277665-ac8txr3h 112 18 . . . cord-277665-ac8txr3h 113 1 Gene gene NN cord-277665-ac8txr3h 113 2 delivery delivery NN cord-277665-ac8txr3h 113 3 is be VBZ cord-277665-ac8txr3h 113 4 achieved achieve VBN cord-277665-ac8txr3h 113 5 using use VBG cord-277665-ac8txr3h 113 6 either either CC cord-277665-ac8txr3h 113 7 viral viral JJ cord-277665-ac8txr3h 113 8 or or CC cord-277665-ac8txr3h 113 9 non non JJ cord-277665-ac8txr3h 113 10 - - JJ cord-277665-ac8txr3h 113 11 viral viral JJ cord-277665-ac8txr3h 113 12 vectors vector NNS cord-277665-ac8txr3h 113 13 . . . cord-277665-ac8txr3h 114 1 Viral viral JJ cord-277665-ac8txr3h 114 2 vectors vector NNS cord-277665-ac8txr3h 114 3 are be VBP cord-277665-ac8txr3h 114 4 genetically genetically RB cord-277665-ac8txr3h 114 5 engineered engineer VBN cord-277665-ac8txr3h 114 6 adenoviruses adenovirus NNS cord-277665-ac8txr3h 114 7 , , , cord-277665-ac8txr3h 114 8 retroviruses retrovirus NNS cord-277665-ac8txr3h 114 9 , , , cord-277665-ac8txr3h 114 10 and and CC cord-277665-ac8txr3h 114 11 other other JJ cord-277665-ac8txr3h 114 12 viruses virus NNS cord-277665-ac8txr3h 114 13 that that WDT cord-277665-ac8txr3h 114 14 are be VBP cord-277665-ac8txr3h 114 15 very very RB cord-277665-ac8txr3h 114 16 efficient efficient JJ cord-277665-ac8txr3h 114 17 when when WRB cord-277665-ac8txr3h 114 18 used use VBN cord-277665-ac8txr3h 114 19 for for IN cord-277665-ac8txr3h 114 20 gene gene NN cord-277665-ac8txr3h 114 21 transfer transfer NN cord-277665-ac8txr3h 114 22 in in IN cord-277665-ac8txr3h 114 23 vivo vivo NN cord-277665-ac8txr3h 114 24 . . . cord-277665-ac8txr3h 115 1 Methods method NNS cord-277665-ac8txr3h 115 2 of of IN cord-277665-ac8txr3h 115 3 non non JJ cord-277665-ac8txr3h 115 4 - - JJ cord-277665-ac8txr3h 115 5 viral viral JJ cord-277665-ac8txr3h 115 6 gene gene NN cord-277665-ac8txr3h 115 7 delivery delivery NN cord-277665-ac8txr3h 115 8 , , , cord-277665-ac8txr3h 115 9 including include VBG cord-277665-ac8txr3h 115 10 nanoparticle nanoparticle NN cord-277665-ac8txr3h 115 11 carriers carrier NNS cord-277665-ac8txr3h 115 12 , , , cord-277665-ac8txr3h 115 13 represent represent VBP cord-277665-ac8txr3h 115 14 a a DT cord-277665-ac8txr3h 115 15 small small JJ cord-277665-ac8txr3h 115 16 fraction fraction NN cord-277665-ac8txr3h 115 17 of of IN cord-277665-ac8txr3h 115 18 all all DT cord-277665-ac8txr3h 115 19 methods method NNS cord-277665-ac8txr3h 115 20 used use VBN cord-277665-ac8txr3h 115 21 for for IN cord-277665-ac8txr3h 115 22 transfection transfection NN cord-277665-ac8txr3h 115 23 in in IN cord-277665-ac8txr3h 115 24 vivo vivo NN cord-277665-ac8txr3h 115 25 . . . cord-277665-ac8txr3h 116 1 However however RB cord-277665-ac8txr3h 116 2 , , , cord-277665-ac8txr3h 116 3 they -PRON- PRP cord-277665-ac8txr3h 116 4 have have VBP cord-277665-ac8txr3h 116 5 gradually gradually RB cord-277665-ac8txr3h 116 6 become become VBN cord-277665-ac8txr3h 116 7 as as RB cord-277665-ac8txr3h 116 8 popular popular JJ cord-277665-ac8txr3h 116 9 as as IN cord-277665-ac8txr3h 116 10 the the DT cord-277665-ac8txr3h 116 11 viral viral JJ cord-277665-ac8txr3h 116 12 vector vector NN cord-277665-ac8txr3h 116 13 - - HYPH cord-277665-ac8txr3h 116 14 based base VBN cord-277665-ac8txr3h 116 15 technology technology NN cord-277665-ac8txr3h 116 16 . . . cord-277665-ac8txr3h 117 1 In in IN cord-277665-ac8txr3h 117 2 the the DT cord-277665-ac8txr3h 117 3 development development NN cord-277665-ac8txr3h 117 4 of of IN cord-277665-ac8txr3h 117 5 non non JJ cord-277665-ac8txr3h 117 6 - - JJ cord-277665-ac8txr3h 117 7 viral viral JJ cord-277665-ac8txr3h 117 8 technologies technology NNS cord-277665-ac8txr3h 117 9 , , , cord-277665-ac8txr3h 117 10 the the DT cord-277665-ac8txr3h 117 11 main main JJ cord-277665-ac8txr3h 117 12 goal goal NN cord-277665-ac8txr3h 117 13 is be VBZ cord-277665-ac8txr3h 117 14 to to TO cord-277665-ac8txr3h 117 15 have have VB cord-277665-ac8txr3h 117 16 a a DT cord-277665-ac8txr3h 117 17 transfection transfection NN cord-277665-ac8txr3h 117 18 method method NN cord-277665-ac8txr3h 117 19 that that WDT cord-277665-ac8txr3h 117 20 is be VBZ cord-277665-ac8txr3h 117 21 efficient efficient JJ cord-277665-ac8txr3h 117 22 , , , cord-277665-ac8txr3h 117 23 reproducible reproducible JJ cord-277665-ac8txr3h 117 24 , , , cord-277665-ac8txr3h 117 25 non non JJ cord-277665-ac8txr3h 117 26 - - JJ cord-277665-ac8txr3h 117 27 toxic toxic JJ cord-277665-ac8txr3h 117 28 , , , cord-277665-ac8txr3h 117 29 and and CC cord-277665-ac8txr3h 117 30 allows allow VBZ cord-277665-ac8txr3h 117 31 the the DT cord-277665-ac8txr3h 117 32 prolonged prolong VBN cord-277665-ac8txr3h 117 33 gene gene NN cord-277665-ac8txr3h 117 34 expression expression NN cord-277665-ac8txr3h 117 35 to to TO cord-277665-ac8txr3h 117 36 occur occur VB cord-277665-ac8txr3h 117 37 . . . cord-277665-ac8txr3h 118 1 Efficiency efficiency NN cord-277665-ac8txr3h 118 2 of of IN cord-277665-ac8txr3h 118 3 targeted target VBN cord-277665-ac8txr3h 118 4 delivery delivery NN cord-277665-ac8txr3h 118 5 of of IN cord-277665-ac8txr3h 118 6 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 118 7 loaded load VBN cord-277665-ac8txr3h 118 8 with with IN cord-277665-ac8txr3h 118 9 biologically biologically RB cord-277665-ac8txr3h 118 10 active active JJ cord-277665-ac8txr3h 118 11 molecules molecule NNS cord-277665-ac8txr3h 118 12 is be VBZ cord-277665-ac8txr3h 118 13 affected affect VBN cord-277665-ac8txr3h 118 14 by by IN cord-277665-ac8txr3h 118 15 many many JJ cord-277665-ac8txr3h 118 16 factors factor NNS cord-277665-ac8txr3h 118 17 including include VBG cord-277665-ac8txr3h 118 18 particle particle NN cord-277665-ac8txr3h 118 19 size size NN cord-277665-ac8txr3h 118 20 , , , cord-277665-ac8txr3h 118 21 surface surface NN cord-277665-ac8txr3h 118 22 charge charge NN cord-277665-ac8txr3h 118 23 , , , cord-277665-ac8txr3h 118 24 and and CC cord-277665-ac8txr3h 118 25 chemistry chemistry NN cord-277665-ac8txr3h 118 26 , , , cord-277665-ac8txr3h 118 27 and and CC cord-277665-ac8txr3h 118 28 mechanism mechanism NN cord-277665-ac8txr3h 118 29 of of IN cord-277665-ac8txr3h 118 30 target target NN cord-277665-ac8txr3h 118 31 recognition recognition NN cord-277665-ac8txr3h 118 32 . . . cord-277665-ac8txr3h 119 1 Over over IN cord-277665-ac8txr3h 119 2 the the DT cord-277665-ac8txr3h 119 3 years year NNS cord-277665-ac8txr3h 119 4 , , , cord-277665-ac8txr3h 119 5 a a DT cord-277665-ac8txr3h 119 6 number number NN cord-277665-ac8txr3h 119 7 of of IN cord-277665-ac8txr3h 119 8 natural natural JJ cord-277665-ac8txr3h 119 9 and and CC cord-277665-ac8txr3h 119 10 synthetic synthetic JJ cord-277665-ac8txr3h 119 11 materials material NNS cord-277665-ac8txr3h 119 12 have have VBP cord-277665-ac8txr3h 119 13 been be VBN cord-277665-ac8txr3h 119 14 used use VBN cord-277665-ac8txr3h 119 15 to to TO cord-277665-ac8txr3h 119 16 prepare prepare VB cord-277665-ac8txr3h 119 17 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 119 18 , , , cord-277665-ac8txr3h 119 19 and and CC cord-277665-ac8txr3h 119 20 their -PRON- PRP$ cord-277665-ac8txr3h 119 21 stability stability NN cord-277665-ac8txr3h 119 22 , , , cord-277665-ac8txr3h 119 23 biocompatibility biocompatibility NN cord-277665-ac8txr3h 119 24 , , , cord-277665-ac8txr3h 119 25 and and CC cord-277665-ac8txr3h 119 26 biodegradability biodegradability NN cord-277665-ac8txr3h 119 27 were be VBD cord-277665-ac8txr3h 119 28 investigated investigate VBN cord-277665-ac8txr3h 119 29 ( ( -LRB- cord-277665-ac8txr3h 120 1 Bala Bala NNP cord-277665-ac8txr3h 120 2 et et NNP cord-277665-ac8txr3h 120 3 al al NNP cord-277665-ac8txr3h 120 4 . . NNP cord-277665-ac8txr3h 120 5 , , , cord-277665-ac8txr3h 120 6 2004 2004 CD cord-277665-ac8txr3h 120 7 ) ) -RRB- cord-277665-ac8txr3h 120 8 . . . cord-277665-ac8txr3h 121 1 In in IN cord-277665-ac8txr3h 121 2 some some DT cord-277665-ac8txr3h 121 3 cases case NNS cord-277665-ac8txr3h 121 4 nanocarriers nanocarrier NNS cord-277665-ac8txr3h 121 5 protect protect VBP cord-277665-ac8txr3h 121 6 naked naked JJ cord-277665-ac8txr3h 121 7 DNA dna NN cord-277665-ac8txr3h 121 8 from from IN cord-277665-ac8txr3h 121 9 nucleases nuclease NNS cord-277665-ac8txr3h 121 10 while while IN cord-277665-ac8txr3h 121 11 allowing allow VBG cord-277665-ac8txr3h 121 12 DNA dna NN cord-277665-ac8txr3h 121 13 plasmids plasmid NNS cord-277665-ac8txr3h 121 14 to to TO cord-277665-ac8txr3h 121 15 pass pass VB cord-277665-ac8txr3h 121 16 the the DT cord-277665-ac8txr3h 121 17 cell cell NN cord-277665-ac8txr3h 121 18 membrane membrane NN cord-277665-ac8txr3h 121 19 and and CC cord-277665-ac8txr3h 121 20 get get VB cord-277665-ac8txr3h 121 21 into into IN cord-277665-ac8txr3h 121 22 the the DT cord-277665-ac8txr3h 121 23 nucleus nucleus NN cord-277665-ac8txr3h 122 1 ( ( -LRB- cord-277665-ac8txr3h 122 2 Kneuer Kneuer NNP cord-277665-ac8txr3h 122 3 et et NNP cord-277665-ac8txr3h 122 4 al al NNP cord-277665-ac8txr3h 122 5 . . NNP cord-277665-ac8txr3h 122 6 , , , cord-277665-ac8txr3h 122 7 2000 2000 CD cord-277665-ac8txr3h 122 8 ; ; : cord-277665-ac8txr3h 122 9 Roy Roy NNP cord-277665-ac8txr3h 122 10 et et NNP cord-277665-ac8txr3h 122 11 al al NNP cord-277665-ac8txr3h 122 12 . . NNP cord-277665-ac8txr3h 122 13 , , , cord-277665-ac8txr3h 122 14 2005 2005 CD cord-277665-ac8txr3h 122 15 ) ) -RRB- cord-277665-ac8txr3h 122 16 . . . cord-277665-ac8txr3h 123 1 To to TO cord-277665-ac8txr3h 123 2 optically optically RB cord-277665-ac8txr3h 123 3 monitor monitor VB cord-277665-ac8txr3h 123 4 intracellular intracellular JJ cord-277665-ac8txr3h 123 5 trafficking trafficking NN cord-277665-ac8txr3h 123 6 and and CC cord-277665-ac8txr3h 123 7 gene gene NN cord-277665-ac8txr3h 123 8 transfection transfection NN cord-277665-ac8txr3h 123 9 events event NNS cord-277665-ac8txr3h 123 10 Roy Roy NNP cord-277665-ac8txr3h 123 11 et et NNP cord-277665-ac8txr3h 123 12 al al NNP cord-277665-ac8txr3h 123 13 . . . cord-277665-ac8txr3h 124 1 ( ( -LRB- cord-277665-ac8txr3h 124 2 2005 2005 CD cord-277665-ac8txr3h 124 3 ) ) -RRB- cord-277665-ac8txr3h 124 4 first first RB cord-277665-ac8txr3h 124 5 prepared prepare VBD cord-277665-ac8txr3h 124 6 fluorescently fluorescently RB cord-277665-ac8txr3h 124 7 labeled label VBN cord-277665-ac8txr3h 124 8 organically organically RB cord-277665-ac8txr3h 124 9 modified modify VBN cord-277665-ac8txr3h 124 10 silica silica NN cord-277665-ac8txr3h 124 11 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 124 12 for for IN cord-277665-ac8txr3h 124 13 use use NN cord-277665-ac8txr3h 124 14 in in IN cord-277665-ac8txr3h 124 15 non non JJ cord-277665-ac8txr3h 124 16 - - JJ cord-277665-ac8txr3h 124 17 viral viral JJ cord-277665-ac8txr3h 124 18 gene gene NN cord-277665-ac8txr3h 124 19 delivery delivery NN cord-277665-ac8txr3h 124 20 and and CC cord-277665-ac8txr3h 124 21 biophotonics biophotonic NNS cord-277665-ac8txr3h 124 22 applications application NNS cord-277665-ac8txr3h 124 23 and and CC cord-277665-ac8txr3h 124 24 then then RB cord-277665-ac8txr3h 124 25 showed show VBD cord-277665-ac8txr3h 124 26 that that IN cord-277665-ac8txr3h 124 27 these these DT cord-277665-ac8txr3h 124 28 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 124 29 can can MD cord-277665-ac8txr3h 124 30 serve serve VB cord-277665-ac8txr3h 124 31 as as IN cord-277665-ac8txr3h 124 32 a a DT cord-277665-ac8txr3h 124 33 delivery delivery NN cord-277665-ac8txr3h 124 34 platform platform NN cord-277665-ac8txr3h 124 35 with with IN cord-277665-ac8txr3h 124 36 superior superior JJ cord-277665-ac8txr3h 124 37 efficacy efficacy NN cord-277665-ac8txr3h 124 38 in in IN cord-277665-ac8txr3h 124 39 targeted target VBN cord-277665-ac8txr3h 124 40 drug drug NN cord-277665-ac8txr3h 124 41 therapy therapy NN cord-277665-ac8txr3h 124 42 and and CC cord-277665-ac8txr3h 124 43 as as IN cord-277665-ac8txr3h 124 44 the the DT cord-277665-ac8txr3h 124 45 realtime realtime JJ cord-277665-ac8txr3h 124 46 monitoring monitoring NN cord-277665-ac8txr3h 124 47 of of IN cord-277665-ac8txr3h 124 48 drug drug NN cord-277665-ac8txr3h 124 49 action action NN cord-277665-ac8txr3h 124 50 . . . cord-277665-ac8txr3h 125 1 The the DT cord-277665-ac8txr3h 125 2 highly highly RB cord-277665-ac8txr3h 125 3 monodispersed monodispersed JJ cord-277665-ac8txr3h 125 4 stable stable JJ cord-277665-ac8txr3h 125 5 water water NN cord-277665-ac8txr3h 125 6 suspensions suspension NNS cord-277665-ac8txr3h 125 7 of of IN cord-277665-ac8txr3h 125 8 the the DT cord-277665-ac8txr3h 125 9 organically organically RB cord-277665-ac8txr3h 125 10 modified modify VBN cord-277665-ac8txr3h 125 11 silica silica NN cord-277665-ac8txr3h 125 12 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 125 13 , , , cord-277665-ac8txr3h 125 14 which which WDT cord-277665-ac8txr3h 125 15 were be VBD cord-277665-ac8txr3h 125 16 labeled label VBN cord-277665-ac8txr3h 125 17 with with IN cord-277665-ac8txr3h 125 18 the the DT cord-277665-ac8txr3h 125 19 fluorescent fluorescent JJ cord-277665-ac8txr3h 125 20 dyes dye NNS cord-277665-ac8txr3h 125 21 and and CC cord-277665-ac8txr3h 125 22 functionalized functionalize VBN cord-277665-ac8txr3h 125 23 by by IN cord-277665-ac8txr3h 125 24 amino amino NN cord-277665-ac8txr3h 125 25 groups group NNS cord-277665-ac8txr3h 125 26 , , , cord-277665-ac8txr3h 125 27 were be VBD cord-277665-ac8txr3h 125 28 prepared prepare VBN cord-277665-ac8txr3h 125 29 using use VBG cord-277665-ac8txr3h 125 30 micelle micelle NN cord-277665-ac8txr3h 125 31 chemistry chemistry NN cord-277665-ac8txr3h 125 32 . . . cord-277665-ac8txr3h 126 1 The the DT cord-277665-ac8txr3h 126 2 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 126 3 efficiently efficiently RB cord-277665-ac8txr3h 126 4 bound bind VBN cord-277665-ac8txr3h 126 5 DNA dna NN cord-277665-ac8txr3h 126 6 due due JJ cord-277665-ac8txr3h 126 7 to to IN cord-277665-ac8txr3h 126 8 positively positively RB cord-277665-ac8txr3h 126 9 charged charge VBN cord-277665-ac8txr3h 126 10 amino amino NN cord-277665-ac8txr3h 126 11 groups group NNS cord-277665-ac8txr3h 126 12 and and CC cord-277665-ac8txr3h 126 13 protected protect VBD cord-277665-ac8txr3h 126 14 it -PRON- PRP cord-277665-ac8txr3h 126 15 from from IN cord-277665-ac8txr3h 126 16 digestion digestion NN cord-277665-ac8txr3h 126 17 by by IN cord-277665-ac8txr3h 126 18 DNase DNase NNP cord-277665-ac8txr3h 126 19 I. I. NNP cord-277665-ac8txr3h 126 20 Imaging Imaging NNP cord-277665-ac8txr3h 126 21 by by IN cord-277665-ac8txr3h 126 22 fluorescence fluorescence NN cord-277665-ac8txr3h 126 23 confocal confocal JJ cord-277665-ac8txr3h 126 24 microscopy microscopy NNS cord-277665-ac8txr3h 126 25 confirmed confirm VBD cord-277665-ac8txr3h 126 26 that that IN cord-277665-ac8txr3h 126 27 in in IN cord-277665-ac8txr3h 126 28 vitro vitro FW cord-277665-ac8txr3h 126 29 cells cell NNS cord-277665-ac8txr3h 126 30 efficiently efficiently RB cord-277665-ac8txr3h 126 31 took take VBD cord-277665-ac8txr3h 126 32 up up RP cord-277665-ac8txr3h 126 33 the the DT cord-277665-ac8txr3h 126 34 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 126 35 in in IN cord-277665-ac8txr3h 126 36 the the DT cord-277665-ac8txr3h 126 37 cytoplasm cytoplasm NN cord-277665-ac8txr3h 126 38 , , , cord-277665-ac8txr3h 126 39 and and CC cord-277665-ac8txr3h 126 40 the the DT cord-277665-ac8txr3h 126 41 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 126 42 delivered deliver VBD cord-277665-ac8txr3h 126 43 DNA DNA NNP cord-277665-ac8txr3h 126 44 to to IN cord-277665-ac8txr3h 126 45 the the DT cord-277665-ac8txr3h 126 46 nucleus nucleus NN cord-277665-ac8txr3h 126 47 . . . cord-277665-ac8txr3h 127 1 Very very RB cord-277665-ac8txr3h 127 2 recently recently RB cord-277665-ac8txr3h 127 3 Bejjani Bejjani NNP cord-277665-ac8txr3h 127 4 et et NNP cord-277665-ac8txr3h 127 5 al al NNP cord-277665-ac8txr3h 127 6 . . . cord-277665-ac8txr3h 128 1 ( ( -LRB- cord-277665-ac8txr3h 128 2 2005 2005 CD cord-277665-ac8txr3h 128 3 ) ) -RRB- cord-277665-ac8txr3h 128 4 reported report VBD cord-277665-ac8txr3h 128 5 the the DT cord-277665-ac8txr3h 128 6 breakthrough breakthrough NN cord-277665-ac8txr3h 128 7 discovery discovery NN cord-277665-ac8txr3h 128 8 that that IN cord-277665-ac8txr3h 128 9 polylactic polylactic JJ cord-277665-ac8txr3h 128 10 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 128 11 enable enable VBP cord-277665-ac8txr3h 128 12 in in IN cord-277665-ac8txr3h 128 13 vivo vivo NN cord-277665-ac8txr3h 128 14 gene gene NN cord-277665-ac8txr3h 128 15 transfer transfer NN cord-277665-ac8txr3h 128 16 and and CC cord-277665-ac8txr3h 128 17 expression expression NN cord-277665-ac8txr3h 128 18 with with IN cord-277665-ac8txr3h 128 19 a a DT cord-277665-ac8txr3h 128 20 high high JJ cord-277665-ac8txr3h 128 21 efficiency efficiency NN cord-277665-ac8txr3h 128 22 . . . cord-277665-ac8txr3h 129 1 Solid solid JJ cord-277665-ac8txr3h 129 2 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 129 3 can can MD cord-277665-ac8txr3h 129 4 be be VB cord-277665-ac8txr3h 129 5 used use VBN cord-277665-ac8txr3h 129 6 to to TO cord-277665-ac8txr3h 129 7 deliver deliver VB cord-277665-ac8txr3h 129 8 drugs drug NNS cord-277665-ac8txr3h 129 9 and and CC cord-277665-ac8txr3h 129 10 biologically biologically RB cord-277665-ac8txr3h 129 11 active active JJ cord-277665-ac8txr3h 129 12 molecules molecule NNS cord-277665-ac8txr3h 129 13 to to IN cord-277665-ac8txr3h 129 14 any any DT cord-277665-ac8txr3h 129 15 body body NN cord-277665-ac8txr3h 129 16 organ organ NN cord-277665-ac8txr3h 129 17 including include VBG cord-277665-ac8txr3h 129 18 the the DT cord-277665-ac8txr3h 129 19 brain brain NN cord-277665-ac8txr3h 129 20 , , , cord-277665-ac8txr3h 129 21 because because IN cord-277665-ac8txr3h 129 22 they -PRON- PRP cord-277665-ac8txr3h 129 23 can can MD cord-277665-ac8txr3h 129 24 cross cross VB cord-277665-ac8txr3h 129 25 the the DT cord-277665-ac8txr3h 129 26 blood blood NN cord-277665-ac8txr3h 129 27 - - HYPH cord-277665-ac8txr3h 129 28 brain brain NN cord-277665-ac8txr3h 129 29 barrier barrier NN cord-277665-ac8txr3h 129 30 ( ( -LRB- cord-277665-ac8txr3h 129 31 Lockman Lockman NNP cord-277665-ac8txr3h 129 32 et et NNP cord-277665-ac8txr3h 129 33 al al NNP cord-277665-ac8txr3h 129 34 . . NNP cord-277665-ac8txr3h 129 35 , , , cord-277665-ac8txr3h 129 36 2002 2002 CD cord-277665-ac8txr3h 129 37 ; ; : cord-277665-ac8txr3h 130 1 Koziara Koziara NNP cord-277665-ac8txr3h 130 2 et et FW cord-277665-ac8txr3h 130 3 al al NNP cord-277665-ac8txr3h 130 4 . . NNP cord-277665-ac8txr3h 130 5 , , , cord-277665-ac8txr3h 130 6 2003 2003 CD cord-277665-ac8txr3h 130 7 ) ) -RRB- cord-277665-ac8txr3h 130 8 . . . cord-277665-ac8txr3h 131 1 The the DT cord-277665-ac8txr3h 131 2 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 131 3 that that WDT cord-277665-ac8txr3h 131 4 are be VBP cord-277665-ac8txr3h 131 5 biodegradable biodegradable JJ cord-277665-ac8txr3h 131 6 in in IN cord-277665-ac8txr3h 131 7 a a DT cord-277665-ac8txr3h 131 8 controlled control VBN cord-277665-ac8txr3h 131 9 way way NN cord-277665-ac8txr3h 131 10 are be VBP cord-277665-ac8txr3h 131 11 likely likely JJ cord-277665-ac8txr3h 131 12 to to TO cord-277665-ac8txr3h 131 13 become become VB cord-277665-ac8txr3h 131 14 the the DT cord-277665-ac8txr3h 131 15 carriers carrier NNS cord-277665-ac8txr3h 131 16 of of IN cord-277665-ac8txr3h 131 17 choice choice NN cord-277665-ac8txr3h 131 18 for for IN cord-277665-ac8txr3h 131 19 in in IN cord-277665-ac8txr3h 131 20 vivo vivo FW cord-277665-ac8txr3h 131 21 non non JJ cord-277665-ac8txr3h 131 22 - - JJ cord-277665-ac8txr3h 131 23 viral viral JJ cord-277665-ac8txr3h 131 24 gene gene NN cord-277665-ac8txr3h 131 25 delivery delivery NN cord-277665-ac8txr3h 131 26 . . . cord-277665-ac8txr3h 132 1 Surfacemodified Surfacemodified NNP cord-277665-ac8txr3h 132 2 and and CC cord-277665-ac8txr3h 132 3 appropriately appropriately RB cord-277665-ac8txr3h 132 4 labeled label VBN cord-277665-ac8txr3h 132 5 ND ND NNP cord-277665-ac8txr3h 132 6 particles particle NNS cord-277665-ac8txr3h 132 7 may may MD cord-277665-ac8txr3h 132 8 also also RB cord-277665-ac8txr3h 132 9 serve serve VB cord-277665-ac8txr3h 132 10 as as IN cord-277665-ac8txr3h 132 11 an an DT cord-277665-ac8txr3h 132 12 efficient efficient JJ cord-277665-ac8txr3h 132 13 platform platform NN cord-277665-ac8txr3h 132 14 for for IN cord-277665-ac8txr3h 132 15 in in IN cord-277665-ac8txr3h 132 16 vivo vivo NN cord-277665-ac8txr3h 132 17 transfection transfection NN cord-277665-ac8txr3h 132 18 . . . cord-277665-ac8txr3h 133 1 However however RB cord-277665-ac8txr3h 133 2 , , , cord-277665-ac8txr3h 133 3 because because IN cord-277665-ac8txr3h 133 4 of of IN cord-277665-ac8txr3h 133 5 the the DT cord-277665-ac8txr3h 133 6 very very RB cord-277665-ac8txr3h 133 7 low low JJ cord-277665-ac8txr3h 133 8 , , , cord-277665-ac8txr3h 133 9 if if IN cord-277665-ac8txr3h 133 10 any any DT cord-277665-ac8txr3h 133 11 , , , cord-277665-ac8txr3h 133 12 biodegradability biodegradability NN cord-277665-ac8txr3h 133 13 of of IN cord-277665-ac8txr3h 133 14 ND ND NNP cord-277665-ac8txr3h 133 15 , , , cord-277665-ac8txr3h 133 16 ND ND NNP cord-277665-ac8txr3h 133 17 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 133 18 , , , cord-277665-ac8txr3h 133 19 when when WRB cord-277665-ac8txr3h 133 20 applied apply VBN cord-277665-ac8txr3h 133 21 in in IN cord-277665-ac8txr3h 133 22 vivo vivo NNP cord-277665-ac8txr3h 133 23 , , , cord-277665-ac8txr3h 133 24 must must MD cord-277665-ac8txr3h 133 25 be be VB cord-277665-ac8txr3h 133 26 of of IN cord-277665-ac8txr3h 133 27 a a DT cord-277665-ac8txr3h 133 28 size size NN cord-277665-ac8txr3h 133 29 small small JJ cord-277665-ac8txr3h 133 30 enough enough RB cord-277665-ac8txr3h 133 31 to to TO cord-277665-ac8txr3h 133 32 allow allow VB cord-277665-ac8txr3h 133 33 their -PRON- PRP$ cord-277665-ac8txr3h 133 34 excretion excretion NN cord-277665-ac8txr3h 133 35 by by IN cord-277665-ac8txr3h 133 36 the the DT cord-277665-ac8txr3h 133 37 kidney kidney NN cord-277665-ac8txr3h 133 38 or or CC cord-277665-ac8txr3h 133 39 applied apply VBD cord-277665-ac8txr3h 133 40 cutaneously cutaneously NN cord-277665-ac8txr3h 133 41 . . . cord-277665-ac8txr3h 134 1 Immobilization immobilization NN cord-277665-ac8txr3h 134 2 of of IN cord-277665-ac8txr3h 134 3 DNA dna NN cord-277665-ac8txr3h 134 4 on on IN cord-277665-ac8txr3h 134 5 diamond diamond NN cord-277665-ac8txr3h 134 6 surfaces surface NNS cord-277665-ac8txr3h 134 7 via via IN cord-277665-ac8txr3h 134 8 covalent covalent JJ cord-277665-ac8txr3h 134 9 bonding bonding NN cord-277665-ac8txr3h 134 10 has have VBZ cord-277665-ac8txr3h 134 11 been be VBN cord-277665-ac8txr3h 134 12 explored explore VBN cord-277665-ac8txr3h 134 13 intensively intensively RB cord-277665-ac8txr3h 134 14 . . . cord-277665-ac8txr3h 135 1 For for IN cord-277665-ac8txr3h 135 2 example example NN cord-277665-ac8txr3h 135 3 , , , cord-277665-ac8txr3h 135 4 Ushizawa Ushizawa NNP cord-277665-ac8txr3h 135 5 et et NNP cord-277665-ac8txr3h 135 6 al al NNP cord-277665-ac8txr3h 135 7 . . . cord-277665-ac8txr3h 136 1 ( ( -LRB- cord-277665-ac8txr3h 136 2 2002 2002 CD cord-277665-ac8txr3h 136 3 ) ) -RRB- cord-277665-ac8txr3h 136 4 first first RB cord-277665-ac8txr3h 136 5 modified modify VBN cord-277665-ac8txr3h 136 6 diamond diamond NN cord-277665-ac8txr3h 136 7 powder powder NN cord-277665-ac8txr3h 136 8 with with IN cord-277665-ac8txr3h 136 9 particle particle NN cord-277665-ac8txr3h 136 10 sizes size NNS cord-277665-ac8txr3h 136 11 of of IN cord-277665-ac8txr3h 136 12 1 1 CD cord-277665-ac8txr3h 136 13 - - SYM cord-277665-ac8txr3h 136 14 2 2 CD cord-277665-ac8txr3h 136 15 µm µm CD cord-277665-ac8txr3h 136 16 ( ( -LRB- cord-277665-ac8txr3h 136 17 Fig Fig NNP cord-277665-ac8txr3h 136 18 . . . cord-277665-ac8txr3h 136 19 15 15 CD cord-277665-ac8txr3h 136 20 . . . cord-277665-ac8txr3h 136 21 3 3 LS cord-277665-ac8txr3h 136 22 ) ) -RRB- cord-277665-ac8txr3h 136 23 by by IN cord-277665-ac8txr3h 136 24 oxidation oxidation NN cord-277665-ac8txr3h 136 25 in in IN cord-277665-ac8txr3h 136 26 a a DT cord-277665-ac8txr3h 136 27 heated heated JJ cord-277665-ac8txr3h 136 28 mixture mixture NN cord-277665-ac8txr3h 136 29 of of IN cord-277665-ac8txr3h 136 30 sulfuric sulfuric JJ cord-277665-ac8txr3h 136 31 acid acid NN cord-277665-ac8txr3h 136 32 and and CC cord-277665-ac8txr3h 136 33 nitric nitric NN cord-277665-ac8txr3h 136 34 acid acid NN cord-277665-ac8txr3h 136 35 and and CC cord-277665-ac8txr3h 136 36 then then RB cord-277665-ac8txr3h 136 37 converted convert VBD cord-277665-ac8txr3h 136 38 it -PRON- PRP cord-277665-ac8txr3h 136 39 in in IN cord-277665-ac8txr3h 136 40 chlorocarbonyl chlorocarbonyl NN cord-277665-ac8txr3h 136 41 - - HYPH cord-277665-ac8txr3h 136 42 diamond diamond NN cord-277665-ac8txr3h 136 43 by by IN cord-277665-ac8txr3h 136 44 reacting react VBG cord-277665-ac8txr3h 136 45 with with IN cord-277665-ac8txr3h 136 46 thionyl thionyl NNP cord-277665-ac8txr3h 136 47 chloride chloride NN cord-277665-ac8txr3h 136 48 at at IN cord-277665-ac8txr3h 136 49 50 50 CD cord-277665-ac8txr3h 136 50 ° ° NN cord-277665-ac8txr3h 136 51 C c NN cord-277665-ac8txr3h 136 52 for for IN cord-277665-ac8txr3h 136 53 1 1 CD cord-277665-ac8txr3h 136 54 day day NN cord-277665-ac8txr3h 136 55 . . . cord-277665-ac8txr3h 137 1 Chlorocarbonyl chlorocarbonyl NN cord-277665-ac8txr3h 137 2 - - HYPH cord-277665-ac8txr3h 137 3 diamond diamond NN cord-277665-ac8txr3h 137 4 was be VBD cord-277665-ac8txr3h 137 5 then then RB cord-277665-ac8txr3h 137 6 reacted react VBN cord-277665-ac8txr3h 137 7 with with IN cord-277665-ac8txr3h 137 8 thymidine thymidine NN cord-277665-ac8txr3h 137 9 in in IN cord-277665-ac8txr3h 137 10 the the DT cord-277665-ac8txr3h 137 11 presence presence NN cord-277665-ac8txr3h 137 12 of of IN cord-277665-ac8txr3h 137 13 4-dimethylaminopyridine 4-dimethylaminopyridine CD cord-277665-ac8txr3h 137 14 . . . cord-277665-ac8txr3h 138 1 The the DT cord-277665-ac8txr3h 138 2 DNA dna NN cord-277665-ac8txr3h 138 3 was be VBD cord-277665-ac8txr3h 138 4 attached attach VBN cord-277665-ac8txr3h 138 5 to to IN cord-277665-ac8txr3h 138 6 the the DT cord-277665-ac8txr3h 138 7 3′-end 3′-end CD cord-277665-ac8txr3h 138 8 of of IN cord-277665-ac8txr3h 138 9 diamond diamond NN cord-277665-ac8txr3h 138 10 - - HYPH cord-277665-ac8txr3h 138 11 attached attach VBN cord-277665-ac8txr3h 138 12 thymidine thymidine NN cord-277665-ac8txr3h 138 13 by by IN cord-277665-ac8txr3h 138 14 5′-end 5′-end CD cord-277665-ac8txr3h 138 15 phosphatization phosphatization NN cord-277665-ac8txr3h 138 16 . . . cord-277665-ac8txr3h 139 1 The the DT cord-277665-ac8txr3h 139 2 formation formation NN cord-277665-ac8txr3h 139 3 of of IN cord-277665-ac8txr3h 139 4 ester ester NN cord-277665-ac8txr3h 139 5 bonds bond NNS cord-277665-ac8txr3h 139 6 was be VBD cord-277665-ac8txr3h 139 7 confirmed confirm VBN cord-277665-ac8txr3h 139 8 by by IN cord-277665-ac8txr3h 139 9 diffuse diffuse JJ cord-277665-ac8txr3h 139 10 reflectance reflectance NN cord-277665-ac8txr3h 139 11 FTIR FTIR NNP cord-277665-ac8txr3h 139 12 spectroscopic spectroscopic JJ cord-277665-ac8txr3h 139 13 analysis analysis NN cord-277665-ac8txr3h 139 14 . . . cord-277665-ac8txr3h 140 1 Preparation preparation NN cord-277665-ac8txr3h 140 2 of of IN cord-277665-ac8txr3h 140 3 DNA dna NN cord-277665-ac8txr3h 140 4 - - HYPH cord-277665-ac8txr3h 140 5 modified modify VBN cord-277665-ac8txr3h 140 6 diamond diamond NN cord-277665-ac8txr3h 140 7 films film NNS cord-277665-ac8txr3h 140 8 for for IN cord-277665-ac8txr3h 140 9 use use NN cord-277665-ac8txr3h 140 10 in in IN cord-277665-ac8txr3h 140 11 hybridization hybridization NN cord-277665-ac8txr3h 140 12 has have VBZ cord-277665-ac8txr3h 140 13 received receive VBN cord-277665-ac8txr3h 140 14 increased increase VBN cord-277665-ac8txr3h 140 15 attention attention NN cord-277665-ac8txr3h 140 16 . . . cord-277665-ac8txr3h 141 1 The the DT cord-277665-ac8txr3h 141 2 chemical chemical JJ cord-277665-ac8txr3h 141 3 stability stability NN cord-277665-ac8txr3h 141 4 of of IN cord-277665-ac8txr3h 141 5 diamond diamond NN cord-277665-ac8txr3h 141 6 surfaces surface NNS cord-277665-ac8txr3h 141 7 is be VBZ cord-277665-ac8txr3h 141 8 substantially substantially RB cord-277665-ac8txr3h 141 9 greater great JJR cord-277665-ac8txr3h 141 10 than than IN cord-277665-ac8txr3h 141 11 that that DT cord-277665-ac8txr3h 141 12 of of IN cord-277665-ac8txr3h 141 13 gold gold NN cord-277665-ac8txr3h 141 14 or or CC cord-277665-ac8txr3h 141 15 silicon silicon NN cord-277665-ac8txr3h 141 16 surfaces surface NNS cord-277665-ac8txr3h 142 1 ( ( -LRB- cord-277665-ac8txr3h 142 2 Lu Lu NNP cord-277665-ac8txr3h 142 3 et et FW cord-277665-ac8txr3h 142 4 al al NNP cord-277665-ac8txr3h 142 5 . . NNP cord-277665-ac8txr3h 142 6 , , , cord-277665-ac8txr3h 142 7 2004 2004 CD cord-277665-ac8txr3h 142 8 ) ) -RRB- cord-277665-ac8txr3h 142 9 , , , cord-277665-ac8txr3h 142 10 and and CC cord-277665-ac8txr3h 142 11 the the DT cord-277665-ac8txr3h 142 12 DNA dna NN cord-277665-ac8txr3h 142 13 molecules molecule NNS cord-277665-ac8txr3h 142 14 attached attach VBN cord-277665-ac8txr3h 142 15 to to IN cord-277665-ac8txr3h 142 16 the the DT cord-277665-ac8txr3h 142 17 diamond diamond NN cord-277665-ac8txr3h 142 18 surfaces surface NNS cord-277665-ac8txr3h 142 19 are be VBP cord-277665-ac8txr3h 142 20 easily easily RB cord-277665-ac8txr3h 142 21 accessible accessible JJ cord-277665-ac8txr3h 142 22 to to IN cord-277665-ac8txr3h 142 23 enzymes enzyme NNS cord-277665-ac8txr3h 142 24 . . . cord-277665-ac8txr3h 143 1 Nanocrystalline Nanocrystalline NNP cord-277665-ac8txr3h 143 2 diamond diamond NN cord-277665-ac8txr3h 143 3 thin thin JJ cord-277665-ac8txr3h 143 4 films film NNS cord-277665-ac8txr3h 143 5 covalently covalently RB cord-277665-ac8txr3h 143 6 modified modify VBN cord-277665-ac8txr3h 143 7 with with IN cord-277665-ac8txr3h 143 8 DNA dna NN cord-277665-ac8txr3h 143 9 oligonucleotides oligonucleotide NNS cord-277665-ac8txr3h 143 10 following follow VBG cord-277665-ac8txr3h 143 11 the the DT cord-277665-ac8txr3h 143 12 photochemical photochemical JJ cord-277665-ac8txr3h 143 13 modification modification NN cord-277665-ac8txr3h 143 14 of of IN cord-277665-ac8txr3h 143 15 H h NN cord-277665-ac8txr3h 143 16 - - HYPH cord-277665-ac8txr3h 143 17 terminated terminate VBN cord-277665-ac8txr3h 143 18 surfaces surface NNS cord-277665-ac8txr3h 143 19 with with IN cord-277665-ac8txr3h 143 20 amine amine NN cord-277665-ac8txr3h 143 21 groups group NNS cord-277665-ac8txr3h 143 22 provide provide VBP cord-277665-ac8txr3h 143 23 a a DT cord-277665-ac8txr3h 143 24 very very RB cord-277665-ac8txr3h 143 25 stable stable JJ cord-277665-ac8txr3h 143 26 and and CC cord-277665-ac8txr3h 143 27 highly highly RB cord-277665-ac8txr3h 143 28 selective selective JJ cord-277665-ac8txr3h 143 29 platform platform NN cord-277665-ac8txr3h 143 30 for for IN cord-277665-ac8txr3h 143 31 the the DT cord-277665-ac8txr3h 143 32 surface surface NN cord-277665-ac8txr3h 143 33 hybridization hybridization NN cord-277665-ac8txr3h 143 34 reaction reaction NN cord-277665-ac8txr3h 143 35 ( ( -LRB- cord-277665-ac8txr3h 143 36 Yang Yang NNP cord-277665-ac8txr3h 143 37 et et NNP cord-277665-ac8txr3h 143 38 al al NNP cord-277665-ac8txr3h 143 39 . . NNP cord-277665-ac8txr3h 143 40 , , , cord-277665-ac8txr3h 143 41 2002 2002 CD cord-277665-ac8txr3h 143 42 ) ) -RRB- cord-277665-ac8txr3h 143 43 . . . cord-277665-ac8txr3h 144 1 After after IN cord-277665-ac8txr3h 144 2 linking link VBG cord-277665-ac8txr3h 144 3 DNA dna NN cord-277665-ac8txr3h 144 4 to to IN cord-277665-ac8txr3h 144 5 the the DT cord-277665-ac8txr3h 144 6 amine amine NN cord-277665-ac8txr3h 144 7 groups group NNS cord-277665-ac8txr3h 144 8 , , , cord-277665-ac8txr3h 144 9 hybridization hybridization NN cord-277665-ac8txr3h 144 10 reactions reaction NNS cord-277665-ac8txr3h 144 11 with with IN cord-277665-ac8txr3h 144 12 fluorescently fluorescently RB cord-277665-ac8txr3h 144 13 tagged tag VBN cord-277665-ac8txr3h 144 14 complementary complementary JJ cord-277665-ac8txr3h 144 15 and and CC cord-277665-ac8txr3h 144 16 non non JJ cord-277665-ac8txr3h 144 17 - - JJ cord-277665-ac8txr3h 144 18 complementary complementary JJ cord-277665-ac8txr3h 144 19 oligonucleotides oligonucleotide NNS cord-277665-ac8txr3h 144 20 did do VBD cord-277665-ac8txr3h 144 21 not not RB cord-277665-ac8txr3h 144 22 reveal reveal VB cord-277665-ac8txr3h 144 23 any any DT cord-277665-ac8txr3h 144 24 non non JJ cord-277665-ac8txr3h 144 25 - - JJ cord-277665-ac8txr3h 144 26 specific specific JJ cord-277665-ac8txr3h 144 27 adsorption adsorption NN cord-277665-ac8txr3h 144 28 , , , cord-277665-ac8txr3h 144 29 with with IN cord-277665-ac8txr3h 144 30 extremely extremely RB cord-277665-ac8txr3h 144 31 good good JJ cord-277665-ac8txr3h 144 32 selectivity selectivity NN cord-277665-ac8txr3h 144 33 between between IN cord-277665-ac8txr3h 144 34 matched match VBN cord-277665-ac8txr3h 144 35 and and CC cord-277665-ac8txr3h 144 36 mismatched mismatched JJ cord-277665-ac8txr3h 144 37 sequences sequence NNS cord-277665-ac8txr3h 144 38 ( ( -LRB- cord-277665-ac8txr3h 144 39 Yang Yang NNP cord-277665-ac8txr3h 144 40 et et NNP cord-277665-ac8txr3h 144 41 al al NNP cord-277665-ac8txr3h 144 42 . . NNP cord-277665-ac8txr3h 144 43 , , , cord-277665-ac8txr3h 144 44 2002 2002 CD cord-277665-ac8txr3h 144 45 ) ) -RRB- cord-277665-ac8txr3h 144 46 . . . cord-277665-ac8txr3h 145 1 In in IN cord-277665-ac8txr3h 145 2 a a DT cord-277665-ac8txr3h 145 3 similar similar JJ cord-277665-ac8txr3h 145 4 manner manner NN cord-277665-ac8txr3h 145 5 , , , cord-277665-ac8txr3h 145 6 hydrogen hydrogen NN cord-277665-ac8txr3h 145 7 - - HYPH cord-277665-ac8txr3h 145 8 terminated terminate VBN cord-277665-ac8txr3h 145 9 diamond diamond NN cord-277665-ac8txr3h 145 10 substrates substrate NNS cord-277665-ac8txr3h 145 11 were be VBD cord-277665-ac8txr3h 145 12 photochemically photochemically RB cord-277665-ac8txr3h 145 13 converted convert VBN cord-277665-ac8txr3h 145 14 into into IN cord-277665-ac8txr3h 145 15 amine amine NN cord-277665-ac8txr3h 145 16 - - HYPH cord-277665-ac8txr3h 145 17 terminated terminate VBN cord-277665-ac8txr3h 145 18 surfaces surface NNS cord-277665-ac8txr3h 145 19 following follow VBG cord-277665-ac8txr3h 145 20 by by IN cord-277665-ac8txr3h 145 21 linking link VBG cord-277665-ac8txr3h 145 22 to to IN cord-277665-ac8txr3h 145 23 thiol thiol NN cord-277665-ac8txr3h 145 24 - - HYPH cord-277665-ac8txr3h 145 25 terminated terminate VBN cord-277665-ac8txr3h 145 26 DNA dna NN cord-277665-ac8txr3h 145 27 oligonucleotides oligonucleotide NNS cord-277665-ac8txr3h 145 28 reported report VBN cord-277665-ac8txr3h 145 29 by by IN cord-277665-ac8txr3h 145 30 Knickerbocker Knickerbocker NNP cord-277665-ac8txr3h 145 31 et et NNP cord-277665-ac8txr3h 145 32 al al NNP cord-277665-ac8txr3h 145 33 . . . cord-277665-ac8txr3h 146 1 ( ( -LRB- cord-277665-ac8txr3h 146 2 2003 2003 CD cord-277665-ac8txr3h 146 3 ) ) -RRB- cord-277665-ac8txr3h 146 4 . . . cord-277665-ac8txr3h 147 1 The the DT cord-277665-ac8txr3h 147 2 DNA dna NN cord-277665-ac8txr3h 147 3 hybridization hybridization NN cord-277665-ac8txr3h 147 4 on on IN cord-277665-ac8txr3h 147 5 DNA dna NN cord-277665-ac8txr3h 147 6 - - HYPH cord-277665-ac8txr3h 147 7 modified modify VBN cord-277665-ac8txr3h 147 8 polycrystalline polycrystalline NN cord-277665-ac8txr3h 147 9 diamond diamond NN cord-277665-ac8txr3h 147 10 is be VBZ cord-277665-ac8txr3h 147 11 highly highly RB cord-277665-ac8txr3h 147 12 specific specific JJ cord-277665-ac8txr3h 147 13 and and CC cord-277665-ac8txr3h 147 14 when when WRB cord-277665-ac8txr3h 147 15 compared compare VBN cord-277665-ac8txr3h 147 16 to to IN cord-277665-ac8txr3h 147 17 the the DT cord-277665-ac8txr3h 147 18 hybridization hybridization NN cord-277665-ac8txr3h 147 19 on on IN cord-277665-ac8txr3h 147 20 DNA dna NN cord-277665-ac8txr3h 147 21 - - HYPH cord-277665-ac8txr3h 147 22 modified modify VBN cord-277665-ac8txr3h 147 23 surfaces surface NNS cord-277665-ac8txr3h 147 24 of of IN cord-277665-ac8txr3h 147 25 crystalline crystalline JJ cord-277665-ac8txr3h 147 26 silicon silicon NN cord-277665-ac8txr3h 147 27 shows show VBZ cord-277665-ac8txr3h 147 28 that that IN cord-277665-ac8txr3h 147 29 the the DT cord-277665-ac8txr3h 147 30 diamond diamond NN cord-277665-ac8txr3h 147 31 surface surface NN cord-277665-ac8txr3h 147 32 exhibits exhibit VBZ cord-277665-ac8txr3h 147 33 superior superior JJ cord-277665-ac8txr3h 147 34 chemical chemical NN cord-277665-ac8txr3h 147 35 stability stability NN cord-277665-ac8txr3h 147 36 ( ( -LRB- cord-277665-ac8txr3h 147 37 Knickerbocker Knickerbocker NNP cord-277665-ac8txr3h 147 38 et et NNP cord-277665-ac8txr3h 147 39 al al NNP cord-277665-ac8txr3h 147 40 . . NNP cord-277665-ac8txr3h 147 41 , , , cord-277665-ac8txr3h 147 42 2003 2003 CD cord-277665-ac8txr3h 147 43 ) ) -RRB- cord-277665-ac8txr3h 147 44 . . . cord-277665-ac8txr3h 148 1 DNA dna NN cord-277665-ac8txr3h 148 2 - - HYPH cord-277665-ac8txr3h 148 3 modified modify VBN cord-277665-ac8txr3h 148 4 diamond diamond NN cord-277665-ac8txr3h 148 5 surfaces surface NNS cord-277665-ac8txr3h 148 6 are be VBP cord-277665-ac8txr3h 148 7 particularly particularly RB cord-277665-ac8txr3h 148 8 suitable suitable JJ cord-277665-ac8txr3h 148 9 for for IN cord-277665-ac8txr3h 148 10 invasive invasive JJ cord-277665-ac8txr3h 148 11 cleavage cleavage NN cord-277665-ac8txr3h 148 12 reactions reaction NNS cord-277665-ac8txr3h 148 13 , , , cord-277665-ac8txr3h 148 14 in in IN cord-277665-ac8txr3h 148 15 which which WDT cord-277665-ac8txr3h 148 16 introduction introduction NN cord-277665-ac8txr3h 148 17 of of IN cord-277665-ac8txr3h 148 18 target target NN cord-277665-ac8txr3h 148 19 DNA DNA NNP cord-277665-ac8txr3h 148 20 to to IN cord-277665-ac8txr3h 148 21 solution solution NN cord-277665-ac8txr3h 148 22 results result NNS cord-277665-ac8txr3h 148 23 in in IN cord-277665-ac8txr3h 148 24 the the DT cord-277665-ac8txr3h 148 25 specific specific JJ cord-277665-ac8txr3h 148 26 cleavage cleavage NN cord-277665-ac8txr3h 148 27 of of IN cord-277665-ac8txr3h 148 28 surface surface NN cord-277665-ac8txr3h 148 29 - - HYPH cord-277665-ac8txr3h 148 30 bound bind VBN cord-277665-ac8txr3h 148 31 probe probe NN cord-277665-ac8txr3h 148 32 oligonucleotides oligonucleotide NNS cord-277665-ac8txr3h 148 33 , , , cord-277665-ac8txr3h 148 34 permitting permit VBG cord-277665-ac8txr3h 148 35 SNP SNP NNP cord-277665-ac8txr3h 148 36 ( ( -LRB- cord-277665-ac8txr3h 148 37 single single JJ cord-277665-ac8txr3h 148 38 nucleotide nucleotide JJ cord-277665-ac8txr3h 148 39 polymorphisms polymorphism NNS cord-277665-ac8txr3h 148 40 ) ) -RRB- cord-277665-ac8txr3h 148 41 detection detection NN cord-277665-ac8txr3h 148 42 . . . cord-277665-ac8txr3h 149 1 The the DT cord-277665-ac8txr3h 149 2 sensitivity sensitivity NN cord-277665-ac8txr3h 149 3 of of IN cord-277665-ac8txr3h 149 4 the the DT cord-277665-ac8txr3h 149 5 analysis analysis NN cord-277665-ac8txr3h 149 6 can can MD cord-277665-ac8txr3h 149 7 be be VB cord-277665-ac8txr3h 149 8 improved improve VBN cord-277665-ac8txr3h 149 9 100 100 CD cord-277665-ac8txr3h 149 10 times time NNS cord-277665-ac8txr3h 149 11 by by IN cord-277665-ac8txr3h 149 12 replacing replace VBG cord-277665-ac8txr3h 149 13 the the DT cord-277665-ac8txr3h 149 14 DNA dna NN cord-277665-ac8txr3h 149 15 - - HYPH cord-277665-ac8txr3h 149 16 modified modify VBN cord-277665-ac8txr3h 149 17 gold gold NN cord-277665-ac8txr3h 149 18 surface surface NN cord-277665-ac8txr3h 149 19 with with IN cord-277665-ac8txr3h 149 20 a a DT cord-277665-ac8txr3h 149 21 more more RBR cord-277665-ac8txr3h 149 22 stable stable JJ cord-277665-ac8txr3h 149 23 DNA dna NN cord-277665-ac8txr3h 149 24 - - HYPH cord-277665-ac8txr3h 149 25 modified modify VBN cord-277665-ac8txr3h 149 26 diamond diamond NN cord-277665-ac8txr3h 149 27 surface surface NN cord-277665-ac8txr3h 149 28 ( ( -LRB- cord-277665-ac8txr3h 149 29 Lu Lu NNP cord-277665-ac8txr3h 149 30 et et FW cord-277665-ac8txr3h 149 31 al al NNP cord-277665-ac8txr3h 149 32 . . NNP cord-277665-ac8txr3h 149 33 , , , cord-277665-ac8txr3h 149 34 2004 2004 CD cord-277665-ac8txr3h 149 35 ) ) -RRB- cord-277665-ac8txr3h 149 36 . . . cord-277665-ac8txr3h 150 1 CVD CVD NNP cord-277665-ac8txr3h 150 2 diamond diamond NN cord-277665-ac8txr3h 150 3 has have VBZ cord-277665-ac8txr3h 150 4 also also RB cord-277665-ac8txr3h 150 5 found find VBN cord-277665-ac8txr3h 150 6 some some DT cord-277665-ac8txr3h 150 7 applications application NNS cord-277665-ac8txr3h 150 8 for for IN cord-277665-ac8txr3h 150 9 DNA dna NN cord-277665-ac8txr3h 150 10 immobilization immobilization NN cord-277665-ac8txr3h 150 11 . . . cord-277665-ac8txr3h 151 1 Using use VBG cord-277665-ac8txr3h 151 2 thymidine thymidine NN cord-277665-ac8txr3h 151 3 as as IN cord-277665-ac8txr3h 151 4 a a DT cord-277665-ac8txr3h 151 5 linker linker NN cord-277665-ac8txr3h 151 6 molecule molecule NN cord-277665-ac8txr3h 151 7 , , , cord-277665-ac8txr3h 151 8 the the DT cord-277665-ac8txr3h 151 9 fragment fragment NN cord-277665-ac8txr3h 151 10 of of IN cord-277665-ac8txr3h 151 11 the the DT cord-277665-ac8txr3h 151 12 human human JJ cord-277665-ac8txr3h 151 13 PKU PKU NNP cord-277665-ac8txr3h 151 14 gene gene NN cord-277665-ac8txr3h 151 15 was be VBD cord-277665-ac8txr3h 151 16 covalently covalently RB cord-277665-ac8txr3h 151 17 bound bind VBN cord-277665-ac8txr3h 151 18 to to IN cord-277665-ac8txr3h 151 19 the the DT cord-277665-ac8txr3h 151 20 CVD CVD NNP cord-277665-ac8txr3h 151 21 diamond diamond NN cord-277665-ac8txr3h 151 22 film film NN cord-277665-ac8txr3h 151 23 by by IN cord-277665-ac8txr3h 151 24 Wenmackers Wenmackers NNP cord-277665-ac8txr3h 151 25 et et NNP cord-277665-ac8txr3h 151 26 al al NNP cord-277665-ac8txr3h 151 27 . . . cord-277665-ac8txr3h 152 1 ( ( -LRB- cord-277665-ac8txr3h 152 2 2003 2003 CD cord-277665-ac8txr3h 152 3 ) ) -RRB- cord-277665-ac8txr3h 152 4 . . . cord-277665-ac8txr3h 153 1 Boron boron NN cord-277665-ac8txr3h 153 2 - - HYPH cord-277665-ac8txr3h 153 3 doped dope VBN cord-277665-ac8txr3h 153 4 diamond diamond NN cord-277665-ac8txr3h 153 5 ( ( -LRB- cord-277665-ac8txr3h 153 6 BDD BDD NNP cord-277665-ac8txr3h 153 7 ) ) -RRB- cord-277665-ac8txr3h 153 8 thin thin JJ cord-277665-ac8txr3h 153 9 films film NNS cord-277665-ac8txr3h 153 10 with with IN cord-277665-ac8txr3h 153 11 enhanced enhanced JJ cord-277665-ac8txr3h 153 12 conductivity conductivity NN cord-277665-ac8txr3h 153 13 offer offer VBP cord-277665-ac8txr3h 153 14 a a DT cord-277665-ac8txr3h 153 15 substantial substantial JJ cord-277665-ac8txr3h 153 16 advantage advantage NN cord-277665-ac8txr3h 153 17 for for IN cord-277665-ac8txr3h 153 18 use use NN cord-277665-ac8txr3h 153 19 in in IN cord-277665-ac8txr3h 153 20 DNA dna NN cord-277665-ac8txr3h 153 21 hybridization hybridization NN cord-277665-ac8txr3h 153 22 analysis analysis NN cord-277665-ac8txr3h 153 23 . . . cord-277665-ac8txr3h 154 1 For for IN cord-277665-ac8txr3h 154 2 example example NN cord-277665-ac8txr3h 154 3 , , , cord-277665-ac8txr3h 154 4 Gu Gu NNP cord-277665-ac8txr3h 154 5 et et NNP cord-277665-ac8txr3h 154 6 al al NNP cord-277665-ac8txr3h 154 7 . . . cord-277665-ac8txr3h 155 1 ( ( -LRB- cord-277665-ac8txr3h 155 2 2004 2004 CD cord-277665-ac8txr3h 155 3 ) ) -RRB- cord-277665-ac8txr3h 155 4 electropolymerized electropolymerize VBD cord-277665-ac8txr3h 155 5 a a DT cord-277665-ac8txr3h 155 6 thin thin JJ cord-277665-ac8txr3h 155 7 layer layer NN cord-277665-ac8txr3h 155 8 of of IN cord-277665-ac8txr3h 155 9 polyaniline polyaniline NNP cord-277665-ac8txr3h 155 10 / / SYM cord-277665-ac8txr3h 155 11 poly(acrylic poly(acrylic JJ cord-277665-ac8txr3h 155 12 acid acid NN cord-277665-ac8txr3h 155 13 ) ) -RRB- cord-277665-ac8txr3h 155 14 onto onto IN cord-277665-ac8txr3h 155 15 the the DT cord-277665-ac8txr3h 155 16 diamond diamond NN cord-277665-ac8txr3h 155 17 surface surface NN cord-277665-ac8txr3h 155 18 . . . cord-277665-ac8txr3h 156 1 The the DT cord-277665-ac8txr3h 156 2 carboxylic carboxylic JJ cord-277665-ac8txr3h 156 3 acid acid NN cord-277665-ac8txr3h 156 4 residues residue NNS cord-277665-ac8txr3h 156 5 in in IN cord-277665-ac8txr3h 156 6 the the DT cord-277665-ac8txr3h 156 7 polymer polymer NN cord-277665-ac8txr3h 156 8 film film NN cord-277665-ac8txr3h 156 9 enhanced enhance VBD cord-277665-ac8txr3h 156 10 the the DT cord-277665-ac8txr3h 156 11 electron electron NN cord-277665-ac8txr3h 156 12 transfer transfer NN cord-277665-ac8txr3h 156 13 between between IN cord-277665-ac8txr3h 156 14 DNA dna NN cord-277665-ac8txr3h 156 15 and and CC cord-277665-ac8txr3h 156 16 a a DT cord-277665-ac8txr3h 156 17 BDD BDD NNP cord-277665-ac8txr3h 156 18 surface surface NN cord-277665-ac8txr3h 156 19 and and CC cord-277665-ac8txr3h 156 20 acted act VBD cord-277665-ac8txr3h 156 21 as as IN cord-277665-ac8txr3h 156 22 the the DT cord-277665-ac8txr3h 156 23 binding bind VBG cord-277665-ac8txr3h 156 24 sites site NNS cord-277665-ac8txr3h 156 25 for for IN cord-277665-ac8txr3h 156 26 DNA dna NN cord-277665-ac8txr3h 156 27 attachment attachment NN cord-277665-ac8txr3h 156 28 . . . cord-277665-ac8txr3h 157 1 Both both DT cord-277665-ac8txr3h 157 2 fluorescence fluorescence NN cord-277665-ac8txr3h 157 3 microscopy microscopy NNS cord-277665-ac8txr3h 157 4 and and CC cord-277665-ac8txr3h 157 5 cyclic cyclic JJ cord-277665-ac8txr3h 157 6 voltammograms voltammograms NNP cord-277665-ac8txr3h 157 7 indicated indicate VBD cord-277665-ac8txr3h 157 8 that that IN cord-277665-ac8txr3h 157 9 the the DT cord-277665-ac8txr3h 157 10 polymer polymer NN cord-277665-ac8txr3h 157 11 - - HYPH cord-277665-ac8txr3h 157 12 modified modify VBN cord-277665-ac8txr3h 157 13 BDD BDD NNP cord-277665-ac8txr3h 157 14 did do VBD cord-277665-ac8txr3h 157 15 not not RB cord-277665-ac8txr3h 157 16 show show VB cord-277665-ac8txr3h 157 17 significant significant JJ cord-277665-ac8txr3h 157 18 non non JJ cord-277665-ac8txr3h 157 19 - - JJ cord-277665-ac8txr3h 157 20 specific specific JJ cord-277665-ac8txr3h 157 21 DNA dna NN cord-277665-ac8txr3h 157 22 adsorption adsorption NN cord-277665-ac8txr3h 157 23 , , , cord-277665-ac8txr3h 157 24 while while IN cord-277665-ac8txr3h 157 25 providing provide VBG cord-277665-ac8txr3h 157 26 a a DT cord-277665-ac8txr3h 157 27 stable stable JJ cord-277665-ac8txr3h 157 28 transduction transduction NN cord-277665-ac8txr3h 157 29 platform platform NN cord-277665-ac8txr3h 157 30 for for IN cord-277665-ac8txr3h 157 31 DNA dna NN cord-277665-ac8txr3h 157 32 detection detection NN cord-277665-ac8txr3h 157 33 by by IN cord-277665-ac8txr3h 157 34 hybridization hybridization NN cord-277665-ac8txr3h 157 35 . . . cord-277665-ac8txr3h 158 1 The the DT cord-277665-ac8txr3h 158 2 absence absence NN cord-277665-ac8txr3h 158 3 of of IN cord-277665-ac8txr3h 158 4 efficient efficient JJ cord-277665-ac8txr3h 158 5 technology technology NN cord-277665-ac8txr3h 158 6 for for IN cord-277665-ac8txr3h 158 7 in in IN cord-277665-ac8txr3h 158 8 vivo vivo NN cord-277665-ac8txr3h 158 9 delivery delivery NN cord-277665-ac8txr3h 158 10 of of IN cord-277665-ac8txr3h 158 11 oligonucleoticles oligonucleoticles NNP cord-277665-ac8txr3h 158 12 limits limit VBZ cord-277665-ac8txr3h 158 13 many many JJ cord-277665-ac8txr3h 158 14 therapeutic therapeutic JJ cord-277665-ac8txr3h 158 15 applications application NNS cord-277665-ac8txr3h 158 16 . . . cord-277665-ac8txr3h 159 1 For for IN cord-277665-ac8txr3h 159 2 successful successful JJ cord-277665-ac8txr3h 159 3 application application NN cord-277665-ac8txr3h 159 4 in in IN cord-277665-ac8txr3h 159 5 vivo vivo NN cord-277665-ac8txr3h 159 6 , , , cord-277665-ac8txr3h 159 7 in in IN cord-277665-ac8txr3h 159 8 most most JJS cord-277665-ac8txr3h 159 9 cases case NNS cord-277665-ac8txr3h 159 10 in in IN cord-277665-ac8txr3h 159 11 vitro vitro FW cord-277665-ac8txr3h 159 12 delivery delivery NN cord-277665-ac8txr3h 159 13 platforms platform NNS cord-277665-ac8txr3h 159 14 should should MD cord-277665-ac8txr3h 159 15 be be VB cord-277665-ac8txr3h 159 16 extensively extensively RB cord-277665-ac8txr3h 159 17 modified modify VBN cord-277665-ac8txr3h 159 18 in in IN cord-277665-ac8txr3h 159 19 order order NN cord-277665-ac8txr3h 159 20 to to TO cord-277665-ac8txr3h 159 21 provide provide VB cord-277665-ac8txr3h 159 22 targeted targeted JJ cord-277665-ac8txr3h 159 23 drug drug NN cord-277665-ac8txr3h 159 24 delivery delivery NN cord-277665-ac8txr3h 159 25 . . . cord-277665-ac8txr3h 160 1 The the DT cord-277665-ac8txr3h 160 2 adamantanebased adamantanebased JJ cord-277665-ac8txr3h 160 3 materials material NNS cord-277665-ac8txr3h 160 4 have have VBP cord-277665-ac8txr3h 160 5 found find VBN cord-277665-ac8txr3h 160 6 application application NN cord-277665-ac8txr3h 160 7 in in IN cord-277665-ac8txr3h 160 8 the the DT cord-277665-ac8txr3h 160 9 preparation preparation NN cord-277665-ac8txr3h 160 10 of of IN cord-277665-ac8txr3h 160 11 carriers carrier NNS cord-277665-ac8txr3h 160 12 for for IN cord-277665-ac8txr3h 160 13 in in IN cord-277665-ac8txr3h 160 14 vivo vivo NN cord-277665-ac8txr3h 160 15 nucleic nucleic JJ cord-277665-ac8txr3h 160 16 acid acid NN cord-277665-ac8txr3h 160 17 delivery delivery NN cord-277665-ac8txr3h 160 18 because because IN cord-277665-ac8txr3h 160 19 they -PRON- PRP cord-277665-ac8txr3h 160 20 can can MD cord-277665-ac8txr3h 160 21 be be VB cord-277665-ac8txr3h 160 22 modified modify VBN cord-277665-ac8txr3h 160 23 by by IN cord-277665-ac8txr3h 160 24 using use VBG cord-277665-ac8txr3h 160 25 cyclodextrin cyclodextrin NN cord-277665-ac8txr3h 160 26 / / SYM cord-277665-ac8txr3h 160 27 adamantane adamantane NNP cord-277665-ac8txr3h 160 28 host host NN cord-277665-ac8txr3h 160 29 / / SYM cord-277665-ac8txr3h 160 30 guest guest NN cord-277665-ac8txr3h 160 31 interactions interaction NNS cord-277665-ac8txr3h 160 32 to to TO cord-277665-ac8txr3h 160 33 provide provide VB cord-277665-ac8txr3h 160 34 the the DT cord-277665-ac8txr3h 160 35 particles particle NNS cord-277665-ac8txr3h 160 36 suitable suitable JJ cord-277665-ac8txr3h 160 37 for for IN cord-277665-ac8txr3h 160 38 systemic systemic JJ cord-277665-ac8txr3h 160 39 application application NN cord-277665-ac8txr3h 160 40 ( ( -LRB- cord-277665-ac8txr3h 160 41 Pun Pun NNP cord-277665-ac8txr3h 160 42 and and CC cord-277665-ac8txr3h 160 43 Davis Davis NNP cord-277665-ac8txr3h 160 44 , , , cord-277665-ac8txr3h 160 45 2002 2002 CD cord-277665-ac8txr3h 160 46 ) ) -RRB- cord-277665-ac8txr3h 160 47 . . . cord-277665-ac8txr3h 161 1 Transferrinmodified transferrinmodifie VBN cord-277665-ac8txr3h 161 2 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 161 3 containing contain VBG cord-277665-ac8txr3h 161 4 DNAzymes DNAzymes NNP cord-277665-ac8txr3h 161 5 ( ( -LRB- cord-277665-ac8txr3h 161 6 DNA dna NN cord-277665-ac8txr3h 161 7 enzymes enzyme NNS cord-277665-ac8txr3h 161 8 that that WDT cord-277665-ac8txr3h 161 9 are be VBP cord-277665-ac8txr3h 161 10 RNA rna NN cord-277665-ac8txr3h 161 11 - - HYPH cord-277665-ac8txr3h 161 12 cleaving cleave VBG cord-277665-ac8txr3h 161 13 phosphodiester phosphodiester NN cord-277665-ac8txr3h 161 14 - - HYPH cord-277665-ac8txr3h 161 15 linked link VBN cord-277665-ac8txr3h 161 16 DNA dna NN cord-277665-ac8txr3h 161 17 - - HYPH cord-277665-ac8txr3h 161 18 based base VBN cord-277665-ac8txr3h 161 19 enzymes enzyme NNS cord-277665-ac8txr3h 161 20 , , , cord-277665-ac8txr3h 161 21 which which WDT cord-277665-ac8txr3h 161 22 cleave cleave VBP cord-277665-ac8txr3h 161 23 their -PRON- PRP$ cord-277665-ac8txr3h 161 24 target target NN cord-277665-ac8txr3h 161 25 mRNA mrna NN cord-277665-ac8txr3h 161 26 in in IN cord-277665-ac8txr3h 161 27 a a DT cord-277665-ac8txr3h 161 28 gene gene NN cord-277665-ac8txr3h 161 29 - - HYPH cord-277665-ac8txr3h 161 30 specific specific JJ cord-277665-ac8txr3h 161 31 fashion fashion NN cord-277665-ac8txr3h 161 32 ) ) -RRB- cord-277665-ac8txr3h 161 33 for for IN cord-277665-ac8txr3h 161 34 targeting target VBG cord-277665-ac8txr3h 161 35 tumors tumor NNS cord-277665-ac8txr3h 161 36 were be VBD cord-277665-ac8txr3h 161 37 prepared prepare VBN cord-277665-ac8txr3h 161 38 by by IN cord-277665-ac8txr3h 161 39 using use VBG cord-277665-ac8txr3h 161 40 conjugates conjugate NNS cord-277665-ac8txr3h 161 41 of of IN cord-277665-ac8txr3h 161 42 adamantane adamantane NNP cord-277665-ac8txr3h 161 43 with with IN cord-277665-ac8txr3h 161 44 poly(ethylene poly(ethylene JJ cord-277665-ac8txr3h 161 45 glycol glycol NN cord-277665-ac8txr3h 161 46 ) ) -RRB- cord-277665-ac8txr3h 161 47 and and CC cord-277665-ac8txr3h 161 48 administered administer VBN cord-277665-ac8txr3h 161 49 to to IN cord-277665-ac8txr3h 161 50 tumor tumor NN cord-277665-ac8txr3h 161 51 - - HYPH cord-277665-ac8txr3h 161 52 bearing bear VBG cord-277665-ac8txr3h 161 53 nude nude JJ cord-277665-ac8txr3h 161 54 mice mouse NNS cord-277665-ac8txr3h 161 55 by by IN cord-277665-ac8txr3h 161 56 intraperitoneal intraperitoneal JJ cord-277665-ac8txr3h 161 57 bolus bolus NN cord-277665-ac8txr3h 161 58 and and CC cord-277665-ac8txr3h 161 59 infusion infusion NN cord-277665-ac8txr3h 161 60 , , , cord-277665-ac8txr3h 161 61 intravenous intravenous JJ cord-277665-ac8txr3h 161 62 bolus bolus NN cord-277665-ac8txr3h 161 63 , , , cord-277665-ac8txr3h 161 64 and and CC cord-277665-ac8txr3h 161 65 subcutaneous subcutaneous JJ cord-277665-ac8txr3h 161 66 injection injection NN cord-277665-ac8txr3h 161 67 . . . cord-277665-ac8txr3h 162 1 DNAzymes DNAzymes NNP cord-277665-ac8txr3h 162 2 packaged package VBN cord-277665-ac8txr3h 162 3 in in IN cord-277665-ac8txr3h 162 4 polyplex polyplex NN cord-277665-ac8txr3h 162 5 formulations formulation NNS cord-277665-ac8txr3h 162 6 were be VBD cord-277665-ac8txr3h 162 7 concentrated concentrate VBN cord-277665-ac8txr3h 162 8 and and CC cord-277665-ac8txr3h 162 9 retained retain VBN cord-277665-ac8txr3h 162 10 in in IN cord-277665-ac8txr3h 162 11 tumor tumor NN cord-277665-ac8txr3h 162 12 tissue tissue NN cord-277665-ac8txr3h 162 13 , , , cord-277665-ac8txr3h 162 14 whereas whereas IN cord-277665-ac8txr3h 162 15 unformulated unformulate VBN cord-277665-ac8txr3h 162 16 DNAzyme DNAzyme NNP cord-277665-ac8txr3h 162 17 was be VBD cord-277665-ac8txr3h 162 18 eliminated eliminate VBN cord-277665-ac8txr3h 162 19 from from IN cord-277665-ac8txr3h 162 20 the the DT cord-277665-ac8txr3h 162 21 body body NN cord-277665-ac8txr3h 162 22 within within IN cord-277665-ac8txr3h 162 23 24 24 CD cord-277665-ac8txr3h 162 24 hours hour NNS cord-277665-ac8txr3h 162 25 after after IN cord-277665-ac8txr3h 162 26 administration administration NN cord-277665-ac8txr3h 162 27 . . . cord-277665-ac8txr3h 163 1 In in IN cord-277665-ac8txr3h 163 2 wound wound JJ cord-277665-ac8txr3h 163 3 healing healing NN cord-277665-ac8txr3h 163 4 therapy therapy NN cord-277665-ac8txr3h 163 5 , , , cord-277665-ac8txr3h 163 6 the the DT cord-277665-ac8txr3h 163 7 localized localized JJ cord-277665-ac8txr3h 163 8 delivery delivery NN cord-277665-ac8txr3h 163 9 of of IN cord-277665-ac8txr3h 163 10 growth growth NN cord-277665-ac8txr3h 163 11 factors factor NNS cord-277665-ac8txr3h 163 12 is be VBZ cord-277665-ac8txr3h 163 13 achieved achieve VBN cord-277665-ac8txr3h 163 14 by by IN cord-277665-ac8txr3h 163 15 gene gene NN cord-277665-ac8txr3h 163 16 transfer transfer NN cord-277665-ac8txr3h 163 17 to to IN cord-277665-ac8txr3h 163 18 the the DT cord-277665-ac8txr3h 163 19 wound wound NN cord-277665-ac8txr3h 163 20 site site NN cord-277665-ac8txr3h 163 21 . . . cord-277665-ac8txr3h 164 1 Synthetic synthetic JJ cord-277665-ac8txr3h 164 2 biocompatible biocompatible JJ cord-277665-ac8txr3h 164 3 materials material NNS cord-277665-ac8txr3h 164 4 prepared prepare VBN cord-277665-ac8txr3h 164 5 with with IN cord-277665-ac8txr3h 164 6 a a DT cord-277665-ac8txr3h 164 7 linear linear JJ cord-277665-ac8txr3h 164 8 , , , cord-277665-ac8txr3h 164 9 beta beta NN cord-277665-ac8txr3h 164 10 - - HYPH cord-277665-ac8txr3h 164 11 cyclodextrin cyclodextrin NN cord-277665-ac8txr3h 164 12 - - HYPH cord-277665-ac8txr3h 164 13 containing contain VBG cord-277665-ac8txr3h 164 14 polymer polymer NN cord-277665-ac8txr3h 164 15 and and CC cord-277665-ac8txr3h 164 16 an an DT cord-277665-ac8txr3h 164 17 adamantane adamantane NN cord-277665-ac8txr3h 164 18 - - HYPH cord-277665-ac8txr3h 164 19 based base VBN cord-277665-ac8txr3h 164 20 crosslinking crosslinking NN cord-277665-ac8txr3h 164 21 polymer polymer NN cord-277665-ac8txr3h 164 22 are be VBP cord-277665-ac8txr3h 164 23 very very RB cord-277665-ac8txr3h 164 24 suitable suitable JJ cord-277665-ac8txr3h 164 25 for for IN cord-277665-ac8txr3h 164 26 in in IN cord-277665-ac8txr3h 164 27 vivo vivo NN cord-277665-ac8txr3h 164 28 gene gene NN cord-277665-ac8txr3h 164 29 delivery delivery NN cord-277665-ac8txr3h 164 30 to to IN cord-277665-ac8txr3h 164 31 fibroblasts fibroblast NNS cord-277665-ac8txr3h 164 32 via via IN cord-277665-ac8txr3h 164 33 the the DT cord-277665-ac8txr3h 164 34 inclusion inclusion NN cord-277665-ac8txr3h 164 35 of of IN cord-277665-ac8txr3h 164 36 adenoviral adenoviral JJ cord-277665-ac8txr3h 164 37 vectors vector NNS cord-277665-ac8txr3h 164 38 in in IN cord-277665-ac8txr3h 164 39 the the DT cord-277665-ac8txr3h 164 40 synthetic synthetic JJ cord-277665-ac8txr3h 164 41 construct construct NN cord-277665-ac8txr3h 164 42 . . . cord-277665-ac8txr3h 165 1 Gene gene NN cord-277665-ac8txr3h 165 2 - - HYPH cord-277665-ac8txr3h 165 3 deleted delete VBN cord-277665-ac8txr3h 165 4 adenoviral adenoviral JJ cord-277665-ac8txr3h 165 5 vectors vector NNS cord-277665-ac8txr3h 165 6 were be VBD cord-277665-ac8txr3h 165 7 originally originally RB cord-277665-ac8txr3h 165 8 developed develop VBN cord-277665-ac8txr3h 165 9 as as IN cord-277665-ac8txr3h 165 10 delivery delivery NN cord-277665-ac8txr3h 165 11 vehicles vehicle NNS cord-277665-ac8txr3h 165 12 for for IN cord-277665-ac8txr3h 165 13 use use NN cord-277665-ac8txr3h 165 14 in in IN cord-277665-ac8txr3h 165 15 gene gene NN cord-277665-ac8txr3h 165 16 therapy therapy NN cord-277665-ac8txr3h 165 17 trials trial NNS cord-277665-ac8txr3h 165 18 and and CC cord-277665-ac8txr3h 165 19 are be VBP cord-277665-ac8txr3h 165 20 currently currently RB cord-277665-ac8txr3h 165 21 being be VBG cord-277665-ac8txr3h 165 22 developed develop VBN cord-277665-ac8txr3h 165 23 as as IN cord-277665-ac8txr3h 165 24 HIV HIV NNP cord-277665-ac8txr3h 165 25 vaccines vaccine NNS cord-277665-ac8txr3h 165 26 and and CC cord-277665-ac8txr3h 165 27 in in IN cord-277665-ac8txr3h 165 28 other other JJ cord-277665-ac8txr3h 165 29 medical medical JJ cord-277665-ac8txr3h 165 30 applications application NNS cord-277665-ac8txr3h 165 31 . . . cord-277665-ac8txr3h 166 1 From from IN cord-277665-ac8txr3h 166 2 a a DT cord-277665-ac8txr3h 166 3 different different JJ cord-277665-ac8txr3h 166 4 perspective perspective NN cord-277665-ac8txr3h 166 5 , , , cord-277665-ac8txr3h 166 6 in in IN cord-277665-ac8txr3h 166 7 biological biological JJ cord-277665-ac8txr3h 166 8 materials material NNS cord-277665-ac8txr3h 166 9 science science NN cord-277665-ac8txr3h 166 10 and and CC cord-277665-ac8txr3h 166 11 in in IN cord-277665-ac8txr3h 166 12 rapidly rapidly RB cord-277665-ac8txr3h 166 13 emerging emerge VBG cord-277665-ac8txr3h 166 14 angstrom angstrom NN cord-277665-ac8txr3h 166 15 - - HYPH cord-277665-ac8txr3h 166 16 scale scale NN cord-277665-ac8txr3h 166 17 chemical chemical NN cord-277665-ac8txr3h 166 18 engineering engineering NN cord-277665-ac8txr3h 166 19 the the DT cord-277665-ac8txr3h 166 20 nucleic nucleic JJ cord-277665-ac8txr3h 166 21 acids acid NNS cord-277665-ac8txr3h 166 22 are be VBP cord-277665-ac8txr3h 166 23 thought think VBN cord-277665-ac8txr3h 166 24 to to TO cord-277665-ac8txr3h 166 25 find find VB cord-277665-ac8txr3h 166 26 many many JJ cord-277665-ac8txr3h 166 27 applications application NNS cord-277665-ac8txr3h 166 28 in in IN cord-277665-ac8txr3h 166 29 the the DT cord-277665-ac8txr3h 166 30 fabrication fabrication NN cord-277665-ac8txr3h 166 31 of of IN cord-277665-ac8txr3h 166 32 self self NN cord-277665-ac8txr3h 166 33 - - HYPH cord-277665-ac8txr3h 166 34 assembling assemble VBG cord-277665-ac8txr3h 166 35 , , , cord-277665-ac8txr3h 166 36 multi multi JJ cord-277665-ac8txr3h 166 37 - - JJ cord-277665-ac8txr3h 166 38 dimensional dimensional JJ cord-277665-ac8txr3h 166 39 materials material NNS cord-277665-ac8txr3h 166 40 ( ( -LRB- cord-277665-ac8txr3h 166 41 Wengel Wengel NNP cord-277665-ac8txr3h 166 42 , , , cord-277665-ac8txr3h 166 43 2004 2004 CD cord-277665-ac8txr3h 166 44 ) ) -RRB- cord-277665-ac8txr3h 166 45 . . . cord-277665-ac8txr3h 167 1 ND ND NNP cord-277665-ac8txr3h 167 2 and and CC cord-277665-ac8txr3h 167 3 diamondoid diamondoid JJ cord-277665-ac8txr3h 167 4 structures structure NNS cord-277665-ac8txr3h 167 5 can can MD cord-277665-ac8txr3h 167 6 be be VB cord-277665-ac8txr3h 167 7 valuable valuable JJ cord-277665-ac8txr3h 167 8 candidates candidate NNS cord-277665-ac8txr3h 167 9 for for IN cord-277665-ac8txr3h 167 10 crosslinking crosslinking NN cord-277665-ac8txr3h 167 11 of of IN cord-277665-ac8txr3h 167 12 oligonucleatides oligonucleatide NNS cord-277665-ac8txr3h 167 13 in in IN cord-277665-ac8txr3h 167 14 carbon carbon NN cord-277665-ac8txr3h 167 15 - - HYPH cord-277665-ac8txr3h 167 16 based base VBN cord-277665-ac8txr3h 167 17 systems system NNS cord-277665-ac8txr3h 167 18 . . . cord-277665-ac8txr3h 168 1 Both both DT cord-277665-ac8txr3h 168 2 selective selective JJ cord-277665-ac8txr3h 168 3 adsorption adsorption NN cord-277665-ac8txr3h 168 4 of of IN cord-277665-ac8txr3h 168 5 proteins protein NNS cord-277665-ac8txr3h 168 6 and and CC cord-277665-ac8txr3h 168 7 their -PRON- PRP$ cord-277665-ac8txr3h 168 8 immobilization immobilization NN cord-277665-ac8txr3h 168 9 onto onto IN cord-277665-ac8txr3h 168 10 surfaces surface NNS cord-277665-ac8txr3h 168 11 of of IN cord-277665-ac8txr3h 168 12 ND ND NNP cord-277665-ac8txr3h 168 13 particles particle NNS cord-277665-ac8txr3h 168 14 ( ( -LRB- cord-277665-ac8txr3h 168 15 Fig Fig NNP cord-277665-ac8txr3h 168 16 . . . cord-277665-ac8txr3h 168 17 15.4 15.4 CD cord-277665-ac8txr3h 168 18 ) ) -RRB- cord-277665-ac8txr3h 168 19 may may MD cord-277665-ac8txr3h 168 20 be be VB cord-277665-ac8txr3h 168 21 advantageous advantageous JJ cord-277665-ac8txr3h 168 22 in in IN cord-277665-ac8txr3h 168 23 nanobiotechnological nanobiotechnological JJ cord-277665-ac8txr3h 168 24 applications application NNS cord-277665-ac8txr3h 168 25 and and CC cord-277665-ac8txr3h 168 26 medicine medicine NN cord-277665-ac8txr3h 168 27 . . . cord-277665-ac8txr3h 169 1 Fibrinogen fibrinogen NN cord-277665-ac8txr3h 169 2 is be VBZ cord-277665-ac8txr3h 169 3 widely widely RB cord-277665-ac8txr3h 169 4 accepted accept VBN cord-277665-ac8txr3h 169 5 as as IN cord-277665-ac8txr3h 169 6 an an DT cord-277665-ac8txr3h 169 7 indicator indicator NN cord-277665-ac8txr3h 169 8 in in IN cord-277665-ac8txr3h 169 9 a a DT cord-277665-ac8txr3h 169 10 biocompatibility biocompatibility NN cord-277665-ac8txr3h 169 11 test test NN cord-277665-ac8txr3h 169 12 and and CC cord-277665-ac8txr3h 169 13 material material NN cord-277665-ac8txr3h 169 14 - - HYPH cord-277665-ac8txr3h 169 15 caused cause VBN cord-277665-ac8txr3h 169 16 inflammation inflammation NN cord-277665-ac8txr3h 169 17 . . . cord-277665-ac8txr3h 170 1 The the DT cord-277665-ac8txr3h 170 2 adsorption adsorption NN cord-277665-ac8txr3h 170 3 of of IN cord-277665-ac8txr3h 170 4 human human JJ cord-277665-ac8txr3h 170 5 fibrinogen fibrinogen NN cord-277665-ac8txr3h 170 6 on on IN cord-277665-ac8txr3h 170 7 the the DT cord-277665-ac8txr3h 170 8 surface surface NN cord-277665-ac8txr3h 170 9 of of IN cord-277665-ac8txr3h 170 10 chemical chemical NN cord-277665-ac8txr3h 170 11 - - HYPH cord-277665-ac8txr3h 170 12 vapor vapor NN cord-277665-ac8txr3h 170 13 - - HYPH cord-277665-ac8txr3h 170 14 deposited deposit VBN cord-277665-ac8txr3h 170 15 diamond diamond NN cord-277665-ac8txr3h 170 16 has have VBZ cord-277665-ac8txr3h 170 17 been be VBN cord-277665-ac8txr3h 170 18 studied study VBN cord-277665-ac8txr3h 170 19 by by IN cord-277665-ac8txr3h 170 20 Tang Tang NNP cord-277665-ac8txr3h 170 21 et et NNP cord-277665-ac8txr3h 170 22 al al NNP cord-277665-ac8txr3h 170 23 . . . cord-277665-ac8txr3h 171 1 ( ( -LRB- cord-277665-ac8txr3h 171 2 1995 1995 CD cord-277665-ac8txr3h 171 3 ) ) -RRB- cord-277665-ac8txr3h 172 1 and and CC cord-277665-ac8txr3h 172 2 was be VBD cord-277665-ac8txr3h 172 3 the the DT cord-277665-ac8txr3h 172 4 first first JJ cord-277665-ac8txr3h 172 5 report report NN cord-277665-ac8txr3h 172 6 on on IN cord-277665-ac8txr3h 172 7 the the DT cord-277665-ac8txr3h 172 8 diamond diamond NN cord-277665-ac8txr3h 172 9 interaction interaction NN cord-277665-ac8txr3h 172 10 with with IN cord-277665-ac8txr3h 172 11 Choi Choi NNP cord-277665-ac8txr3h 172 12 , , , cord-277665-ac8txr3h 172 13 2004 2004 CD cord-277665-ac8txr3h 172 14 . . . cord-277665-ac8txr3h 172 15 ) ) -RRB- cord-277665-ac8txr3h 173 1 a a DT cord-277665-ac8txr3h 173 2 protein protein NN cord-277665-ac8txr3h 173 3 and and CC cord-277665-ac8txr3h 173 4 its -PRON- PRP$ cord-277665-ac8txr3h 173 5 biocompatibility biocompatibility NN cord-277665-ac8txr3h 173 6 . . . cord-277665-ac8txr3h 174 1 The the DT cord-277665-ac8txr3h 174 2 CVD CVD NNP cord-277665-ac8txr3h 174 3 diamond diamond NN cord-277665-ac8txr3h 174 4 was be VBD cord-277665-ac8txr3h 174 5 found find VBN cord-277665-ac8txr3h 174 6 to to TO cord-277665-ac8txr3h 174 7 be be VB cord-277665-ac8txr3h 174 8 biologically biologically RB cord-277665-ac8txr3h 174 9 compatible compatible JJ cord-277665-ac8txr3h 174 10 to to IN cord-277665-ac8txr3h 174 11 the the DT cord-277665-ac8txr3h 174 12 same same JJ cord-277665-ac8txr3h 174 13 extent extent NN cord-277665-ac8txr3h 174 14 as as IN cord-277665-ac8txr3h 174 15 titanium titanium NN cord-277665-ac8txr3h 174 16 and and CC cord-277665-ac8txr3h 174 17 stainless stainless JJ cord-277665-ac8txr3h 174 18 steel steel NN cord-277665-ac8txr3h 174 19 . . . cord-277665-ac8txr3h 175 1 In in IN cord-277665-ac8txr3h 175 2 1995 1995 CD cord-277665-ac8txr3h 175 3 Kossovsky Kossovsky NNP cord-277665-ac8txr3h 175 4 et et NNP cord-277665-ac8txr3h 175 5 al al NNP cord-277665-ac8txr3h 175 6 . . NNP cord-277665-ac8txr3h 175 7 demonstrated demonstrate VBD cord-277665-ac8txr3h 175 8 that that IN cord-277665-ac8txr3h 175 9 surface surface NN cord-277665-ac8txr3h 175 10 - - HYPH cord-277665-ac8txr3h 175 11 modified modify VBN cord-277665-ac8txr3h 175 12 ND ND NNP cord-277665-ac8txr3h 175 13 particles particle NNS cord-277665-ac8txr3h 175 14 with with IN cord-277665-ac8txr3h 175 15 a a DT cord-277665-ac8txr3h 175 16 size size NN cord-277665-ac8txr3h 175 17 ranging range VBG cord-277665-ac8txr3h 175 18 from from IN cord-277665-ac8txr3h 175 19 5 5 CD cord-277665-ac8txr3h 175 20 to to IN cord-277665-ac8txr3h 175 21 300 300 CD cord-277665-ac8txr3h 175 22 nm nm NN cord-277665-ac8txr3h 175 23 provided provide VBD cord-277665-ac8txr3h 175 24 both both DT cord-277665-ac8txr3h 175 25 conformational conformational JJ cord-277665-ac8txr3h 175 26 stabilization stabilization NN cord-277665-ac8txr3h 175 27 and and CC cord-277665-ac8txr3h 175 28 a a DT cord-277665-ac8txr3h 175 29 high high JJ cord-277665-ac8txr3h 175 30 degree degree NN cord-277665-ac8txr3h 175 31 of of IN cord-277665-ac8txr3h 175 32 surface surface NN cord-277665-ac8txr3h 175 33 exposure exposure NN cord-277665-ac8txr3h 175 34 to to IN cord-277665-ac8txr3h 175 35 protein protein NN cord-277665-ac8txr3h 175 36 antigens antigen NNS cord-277665-ac8txr3h 175 37 and and CC cord-277665-ac8txr3h 175 38 used use VBD cord-277665-ac8txr3h 175 39 them -PRON- PRP cord-277665-ac8txr3h 175 40 to to TO cord-277665-ac8txr3h 175 41 generate generate VB cord-277665-ac8txr3h 175 42 antibodies antibody NNS cord-277665-ac8txr3h 175 43 . . . cord-277665-ac8txr3h 176 1 Recently recently RB cord-277665-ac8txr3h 176 2 Huang Huang NNP cord-277665-ac8txr3h 176 3 and and CC cord-277665-ac8txr3h 176 4 Chang Chang NNP cord-277665-ac8txr3h 176 5 ( ( -LRB- cord-277665-ac8txr3h 176 6 2004 2004 CD cord-277665-ac8txr3h 176 7 ) ) -RRB- cord-277665-ac8txr3h 176 8 developed develop VBD cord-277665-ac8txr3h 176 9 the the DT cord-277665-ac8txr3h 176 10 universal universal JJ cord-277665-ac8txr3h 176 11 procedure procedure NN cord-277665-ac8txr3h 176 12 for for IN cord-277665-ac8txr3h 176 13 protein protein NN cord-277665-ac8txr3h 176 14 immobilization immobilization NN cord-277665-ac8txr3h 176 15 onto onto IN cord-277665-ac8txr3h 176 16 the the DT cord-277665-ac8txr3h 176 17 surface surface NN cord-277665-ac8txr3h 176 18 of of IN cord-277665-ac8txr3h 176 19 5 5 CD cord-277665-ac8txr3h 176 20 nm nm NN cord-277665-ac8txr3h 176 21 ND ND NNP cord-277665-ac8txr3h 176 22 particles particle NNS cord-277665-ac8txr3h 176 23 . . . cord-277665-ac8txr3h 177 1 It -PRON- PRP cord-277665-ac8txr3h 177 2 starts start VBZ cord-277665-ac8txr3h 177 3 with with IN cord-277665-ac8txr3h 177 4 ND ND NNP cord-277665-ac8txr3h 177 5 particles particle NNS cord-277665-ac8txr3h 177 6 with with IN cord-277665-ac8txr3h 177 7 strong strong JJ cord-277665-ac8txr3h 177 8 acids acid NNS cord-277665-ac8txr3h 177 9 followed follow VBN cord-277665-ac8txr3h 177 10 by by IN cord-277665-ac8txr3h 177 11 modifying modify VBG cord-277665-ac8txr3h 177 12 their -PRON- PRP$ cord-277665-ac8txr3h 177 13 surface surface NN cord-277665-ac8txr3h 177 14 with with IN cord-277665-ac8txr3h 177 15 poly poly NNP cord-277665-ac8txr3h 177 16 - - HYPH cord-277665-ac8txr3h 177 17 L l NN cord-277665-ac8txr3h 177 18 - - HYPH cord-277665-ac8txr3h 177 19 lysine lysine NN cord-277665-ac8txr3h 177 20 . . . cord-277665-ac8txr3h 178 1 Covalent covalent JJ cord-277665-ac8txr3h 178 2 attachment attachment NN cord-277665-ac8txr3h 178 3 of of IN cord-277665-ac8txr3h 178 4 proteins protein NNS cord-277665-ac8txr3h 178 5 is be VBZ cord-277665-ac8txr3h 178 6 then then RB cord-277665-ac8txr3h 178 7 carried carry VBN cord-277665-ac8txr3h 178 8 out out RP cord-277665-ac8txr3h 178 9 by by IN cord-277665-ac8txr3h 178 10 activating activate VBG cord-277665-ac8txr3h 178 11 the the DT cord-277665-ac8txr3h 178 12 amine amine NN cord-277665-ac8txr3h 178 13 - - HYPH cord-277665-ac8txr3h 178 14 terminated terminate VBN cord-277665-ac8txr3h 178 15 ND ND NNP cord-277665-ac8txr3h 178 16 to to TO cord-277665-ac8txr3h 178 17 react react VB cord-277665-ac8txr3h 178 18 with with IN cord-277665-ac8txr3h 178 19 the the DT cord-277665-ac8txr3h 178 20 heterobifunctional heterobifunctional JJ cord-277665-ac8txr3h 178 21 linker linker NN cord-277665-ac8txr3h 178 22 SSMCC SSMCC NNP cord-277665-ac8txr3h 178 23 followed follow VBD cord-277665-ac8txr3h 178 24 by by IN cord-277665-ac8txr3h 178 25 mixing mix VBG cord-277665-ac8txr3h 178 26 with with IN cord-277665-ac8txr3h 178 27 the the DT cord-277665-ac8txr3h 178 28 protein protein NN cord-277665-ac8txr3h 178 29 . . . cord-277665-ac8txr3h 179 1 The the DT cord-277665-ac8txr3h 179 2 researchers researcher NNS cord-277665-ac8txr3h 179 3 successfully successfully RB cord-277665-ac8txr3h 179 4 immobilized immobilize VBD cord-277665-ac8txr3h 179 5 both both CC cord-277665-ac8txr3h 179 6 Alexa Alexa NNP cord-277665-ac8txr3h 179 7 Fluor Fluor NNP cord-277665-ac8txr3h 179 8 488 488 CD cord-277665-ac8txr3h 179 9 dye dye NN cord-277665-ac8txr3h 179 10 and and CC cord-277665-ac8txr3h 179 11 yeast yeast NN cord-277665-ac8txr3h 179 12 cytochrome cytochrome NN cord-277665-ac8txr3h 179 13 c c NN cord-277665-ac8txr3h 179 14 using use VBG cord-277665-ac8txr3h 179 15 the the DT cord-277665-ac8txr3h 179 16 free free JJ cord-277665-ac8txr3h 179 17 SH SH NNP cord-277665-ac8txr3h 179 18 group group NN cord-277665-ac8txr3h 179 19 for for IN cord-277665-ac8txr3h 179 20 linkage linkage NN cord-277665-ac8txr3h 179 21 . . . cord-277665-ac8txr3h 180 1 More More JJR cord-277665-ac8txr3h 180 2 information information NN cord-277665-ac8txr3h 180 3 on on IN cord-277665-ac8txr3h 180 4 the the DT cord-277665-ac8txr3h 180 5 application application NN cord-277665-ac8txr3h 180 6 of of IN cord-277665-ac8txr3h 180 7 protein protein NN cord-277665-ac8txr3h 180 8 - - HYPH cord-277665-ac8txr3h 180 9 modified modify VBN cord-277665-ac8txr3h 180 10 ND ND NNP cord-277665-ac8txr3h 180 11 in in IN cord-277665-ac8txr3h 180 12 biosensing biosensing NN cord-277665-ac8txr3h 180 13 and and CC cord-277665-ac8txr3h 180 14 biotechnology biotechnology NN cord-277665-ac8txr3h 180 15 can can MD cord-277665-ac8txr3h 180 16 be be VB cord-277665-ac8txr3h 180 17 found find VBN cord-277665-ac8txr3h 180 18 in in IN cord-277665-ac8txr3h 180 19 Section section NN cord-277665-ac8txr3h 180 20 15.5 15.5 CD cord-277665-ac8txr3h 180 21 . . . cord-277665-ac8txr3h 181 1 Hollow hollow JJ cord-277665-ac8txr3h 181 2 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 181 3 are be VBP cord-277665-ac8txr3h 181 4 thought think VBN cord-277665-ac8txr3h 181 5 to to TO cord-277665-ac8txr3h 181 6 be be VB cord-277665-ac8txr3h 181 7 the the DT cord-277665-ac8txr3h 181 8 most most RBS cord-277665-ac8txr3h 181 9 suitable suitable JJ cord-277665-ac8txr3h 181 10 carriers carrier NNS cord-277665-ac8txr3h 181 11 of of IN cord-277665-ac8txr3h 181 12 proteins protein NNS cord-277665-ac8txr3h 181 13 and and CC cord-277665-ac8txr3h 181 14 peptides peptide NNS cord-277665-ac8txr3h 181 15 susceptible susceptible JJ cord-277665-ac8txr3h 181 16 to to IN cord-277665-ac8txr3h 181 17 degradation degradation NN cord-277665-ac8txr3h 181 18 . . . cord-277665-ac8txr3h 182 1 Many many JJ cord-277665-ac8txr3h 182 2 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 182 3 can can MD cord-277665-ac8txr3h 182 4 be be VB cord-277665-ac8txr3h 182 5 made make VBN cord-277665-ac8txr3h 182 6 hollow hollow JJ cord-277665-ac8txr3h 182 7 by by IN cord-277665-ac8txr3h 182 8 heating heating NN cord-277665-ac8txr3h 182 9 at at IN cord-277665-ac8txr3h 182 10 high high JJ cord-277665-ac8txr3h 182 11 temperature temperature NN cord-277665-ac8txr3h 182 12 , , , cord-277665-ac8txr3h 182 13 treating treat VBG cord-277665-ac8txr3h 182 14 with with IN cord-277665-ac8txr3h 182 15 strong strong JJ cord-277665-ac8txr3h 182 16 acids acid NNS cord-277665-ac8txr3h 182 17 , , , cord-277665-ac8txr3h 182 18 alkali alkali JJ cord-277665-ac8txr3h 182 19 , , , cord-277665-ac8txr3h 182 20 and and CC cord-277665-ac8txr3h 182 21 organic organic JJ cord-277665-ac8txr3h 182 22 solvents solvent NNS cord-277665-ac8txr3h 182 23 , , , cord-277665-ac8txr3h 182 24 or or CC cord-277665-ac8txr3h 182 25 using use VBG cord-277665-ac8txr3h 182 26 gentle gentle JJ cord-277665-ac8txr3h 182 27 chemical chemical NN cord-277665-ac8txr3h 182 28 treatment treatment NN cord-277665-ac8txr3h 182 29 to to TO cord-277665-ac8txr3h 182 30 encapsulate encapsulate VB cord-277665-ac8txr3h 182 31 susceptible susceptible JJ cord-277665-ac8txr3h 182 32 organic organic JJ cord-277665-ac8txr3h 182 33 molecules molecule NNS cord-277665-ac8txr3h 182 34 such such JJ cord-277665-ac8txr3h 182 35 as as IN cord-277665-ac8txr3h 182 36 proteins protein NNS cord-277665-ac8txr3h 182 37 , , , cord-277665-ac8txr3h 182 38 peptides peptide NNS cord-277665-ac8txr3h 182 39 , , , cord-277665-ac8txr3h 182 40 and and CC cord-277665-ac8txr3h 182 41 enzymes enzyme NNS cord-277665-ac8txr3h 182 42 or or CC cord-277665-ac8txr3h 182 43 others other NNS cord-277665-ac8txr3h 182 44 inside inside IN cord-277665-ac8txr3h 182 45 the the DT cord-277665-ac8txr3h 182 46 cavity cavity NN cord-277665-ac8txr3h 182 47 of of IN cord-277665-ac8txr3h 182 48 hollow hollow JJ cord-277665-ac8txr3h 182 49 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 182 50 ( ( -LRB- cord-277665-ac8txr3h 182 51 Sharma Sharma NNP cord-277665-ac8txr3h 182 52 et et NNP cord-277665-ac8txr3h 182 53 al al NNP cord-277665-ac8txr3h 182 54 . . NNP cord-277665-ac8txr3h 182 55 , , , cord-277665-ac8txr3h 182 56 2005 2005 CD cord-277665-ac8txr3h 182 57 ) ) -RRB- cord-277665-ac8txr3h 182 58 . . . cord-277665-ac8txr3h 183 1 ND ND NNP cord-277665-ac8txr3h 183 2 particles particle NNS cord-277665-ac8txr3h 183 3 produced produce VBN cord-277665-ac8txr3h 183 4 by by IN cord-277665-ac8txr3h 183 5 detonation detonation NN cord-277665-ac8txr3h 183 6 of of IN cord-277665-ac8txr3h 183 7 the the DT cord-277665-ac8txr3h 183 8 mixture mixture NN cord-277665-ac8txr3h 183 9 of of IN cord-277665-ac8txr3h 183 10 trinitrotoluene trinitrotoluene NNP cord-277665-ac8txr3h 183 11 and and CC cord-277665-ac8txr3h 183 12 cyclomethylenetrinitramine cyclomethylenetrinitramine NNP cord-277665-ac8txr3h 183 13 have have VBP cord-277665-ac8txr3h 183 14 a a DT cord-277665-ac8txr3h 183 15 tetragonal tetragonal JJ cord-277665-ac8txr3h 183 16 structure structure NN cord-277665-ac8txr3h 183 17 and and CC cord-277665-ac8txr3h 183 18 according accord VBG cord-277665-ac8txr3h 183 19 to to IN cord-277665-ac8txr3h 183 20 Vereshchagin Vereshchagin NNP cord-277665-ac8txr3h 183 21 and and CC cord-277665-ac8txr3h 183 22 Yurjev Yurjev NNP cord-277665-ac8txr3h 183 23 ( ( -LRB- cord-277665-ac8txr3h 183 24 2003 2003 CD cord-277665-ac8txr3h 183 25 ) ) -RRB- cord-277665-ac8txr3h 183 26 are be VBP cord-277665-ac8txr3h 183 27 hollow hollow JJ cord-277665-ac8txr3h 183 28 particles particle NNS cord-277665-ac8txr3h 183 29 with with IN cord-277665-ac8txr3h 183 30 an an DT cord-277665-ac8txr3h 183 31 inner inner JJ cord-277665-ac8txr3h 183 32 diameter diameter NN cord-277665-ac8txr3h 183 33 of of IN cord-277665-ac8txr3h 183 34 18.94 18.94 CD cord-277665-ac8txr3h 183 35 Å å NN cord-277665-ac8txr3h 183 36 and and CC cord-277665-ac8txr3h 183 37 outer outer JJ cord-277665-ac8txr3h 183 38 diameter diameter NN cord-277665-ac8txr3h 183 39 of of IN cord-277665-ac8txr3h 183 40 25.47 25.47 CD cord-277665-ac8txr3h 183 41 Å. Å. NNP cord-277665-ac8txr3h 183 42 Yurjev Yurjev NNP cord-277665-ac8txr3h 183 43 et et FW cord-277665-ac8txr3h 183 44 al al NNP cord-277665-ac8txr3h 183 45 . . . cord-277665-ac8txr3h 184 1 ( ( -LRB- cord-277665-ac8txr3h 184 2 2005 2005 CD cord-277665-ac8txr3h 184 3 ) ) -RRB- cord-277665-ac8txr3h 184 4 used use VBD cord-277665-ac8txr3h 184 5 synchrotron synchrotron NN cord-277665-ac8txr3h 184 6 X x NN cord-277665-ac8txr3h 184 7 - - NN cord-277665-ac8txr3h 184 8 ray ray NN cord-277665-ac8txr3h 184 9 diffraction diffraction NN cord-277665-ac8txr3h 184 10 to to TO cord-277665-ac8txr3h 184 11 characterize characterize VB cord-277665-ac8txr3h 184 12 these these DT cord-277665-ac8txr3h 184 13 spherical spherical JJ cord-277665-ac8txr3h 184 14 hollow hollow JJ cord-277665-ac8txr3h 184 15 detonation detonation NN cord-277665-ac8txr3h 184 16 NDs nd NNS cord-277665-ac8txr3h 184 17 that that WDT cord-277665-ac8txr3h 184 18 can can MD cord-277665-ac8txr3h 184 19 be be VB cord-277665-ac8txr3h 184 20 modified modify VBN cord-277665-ac8txr3h 184 21 even even RB cord-277665-ac8txr3h 184 22 further far RBR cord-277665-ac8txr3h 184 23 by by IN cord-277665-ac8txr3h 184 24 grinding grind VBG cord-277665-ac8txr3h 184 25 in in IN cord-277665-ac8txr3h 184 26 a a DT cord-277665-ac8txr3h 184 27 planetary planetary JJ cord-277665-ac8txr3h 184 28 mill mill NN cord-277665-ac8txr3h 184 29 . . . cord-277665-ac8txr3h 185 1 The the DT cord-277665-ac8txr3h 185 2 surface surface NN cord-277665-ac8txr3h 185 3 - - HYPH cord-277665-ac8txr3h 185 4 modified modify VBN cord-277665-ac8txr3h 185 5 NDs nd NNS cord-277665-ac8txr3h 185 6 and and CC cord-277665-ac8txr3h 185 7 diamondoids diamondoid NNS cord-277665-ac8txr3h 185 8 are be VBP cord-277665-ac8txr3h 185 9 expected expect VBN cord-277665-ac8txr3h 185 10 to to TO cord-277665-ac8txr3h 185 11 find find VB cord-277665-ac8txr3h 185 12 vast vast JJ cord-277665-ac8txr3h 185 13 application application NN cord-277665-ac8txr3h 185 14 in in IN cord-277665-ac8txr3h 185 15 the the DT cord-277665-ac8txr3h 185 16 development development NN cord-277665-ac8txr3h 185 17 of of IN cord-277665-ac8txr3h 185 18 a a DT cord-277665-ac8txr3h 185 19 new new JJ cord-277665-ac8txr3h 185 20 generation generation NN cord-277665-ac8txr3h 185 21 of of IN cord-277665-ac8txr3h 185 22 protein protein NN cord-277665-ac8txr3h 185 23 delivery delivery NN cord-277665-ac8txr3h 185 24 platforms platform NNS cord-277665-ac8txr3h 185 25 and and CC cord-277665-ac8txr3h 185 26 antigen antigen NN cord-277665-ac8txr3h 185 27 carriers carrier NNS cord-277665-ac8txr3h 185 28 because because IN cord-277665-ac8txr3h 185 29 they -PRON- PRP cord-277665-ac8txr3h 185 30 can can MD cord-277665-ac8txr3h 185 31 be be VB cord-277665-ac8txr3h 185 32 readily readily RB cord-277665-ac8txr3h 185 33 modified modify VBN cord-277665-ac8txr3h 185 34 to to IN cord-277665-ac8txr3h 185 35 both both DT cord-277665-ac8txr3h 185 36 carry carry VB cord-277665-ac8txr3h 185 37 and and CC cord-277665-ac8txr3h 185 38 stabilize stabilize VBP cord-277665-ac8txr3h 185 39 biologically biologically RB cord-277665-ac8txr3h 185 40 active active JJ cord-277665-ac8txr3h 185 41 molecules molecule NNS cord-277665-ac8txr3h 185 42 , , , cord-277665-ac8txr3h 185 43 proteins protein NNS cord-277665-ac8txr3h 185 44 , , , cord-277665-ac8txr3h 185 45 and and CC cord-277665-ac8txr3h 185 46 enzymes enzyme NNS cord-277665-ac8txr3h 185 47 . . . cord-277665-ac8txr3h 186 1 In in IN cord-277665-ac8txr3h 186 2 addition addition NN cord-277665-ac8txr3h 186 3 , , , cord-277665-ac8txr3h 186 4 these these DT cord-277665-ac8txr3h 186 5 particles particle NNS cord-277665-ac8txr3h 186 6 are be VBP cord-277665-ac8txr3h 186 7 rigid rigid JJ cord-277665-ac8txr3h 186 8 , , , cord-277665-ac8txr3h 186 9 biocompatible biocompatible JJ cord-277665-ac8txr3h 186 10 , , , cord-277665-ac8txr3h 186 11 available available JJ cord-277665-ac8txr3h 186 12 in in IN cord-277665-ac8txr3h 186 13 different different JJ cord-277665-ac8txr3h 186 14 shapes shape NNS cord-277665-ac8txr3h 186 15 , , , cord-277665-ac8txr3h 186 16 and and CC cord-277665-ac8txr3h 186 17 span span VB cord-277665-ac8txr3h 186 18 the the DT cord-277665-ac8txr3h 186 19 subcellular subcellular JJ cord-277665-ac8txr3h 186 20 size size NN cord-277665-ac8txr3h 186 21 range range NN cord-277665-ac8txr3h 186 22 ( ( -LRB- cord-277665-ac8txr3h 186 23 Fig fig NN cord-277665-ac8txr3h 186 24 . . . cord-277665-ac8txr3h 186 25 15.1 15.1 CD cord-277665-ac8txr3h 186 26 ) ) -RRB- cord-277665-ac8txr3h 186 27 . . . cord-277665-ac8txr3h 187 1 A a DT cord-277665-ac8txr3h 187 2 biosensor biosensor NN cord-277665-ac8txr3h 187 3 ( ( -LRB- cord-277665-ac8txr3h 187 4 Fig Fig NNP cord-277665-ac8txr3h 187 5 . . . cord-277665-ac8txr3h 187 6 15 15 CD cord-277665-ac8txr3h 187 7 .5 .5 CD cord-277665-ac8txr3h 187 8 ) ) -RRB- cord-277665-ac8txr3h 187 9 generally generally RB cord-277665-ac8txr3h 187 10 comprises comprise VBZ cord-277665-ac8txr3h 187 11 biomolecules biomolecule NNS cord-277665-ac8txr3h 187 12 sensing sense VBG cord-277665-ac8txr3h 187 13 an an DT cord-277665-ac8txr3h 187 14 analyte analyte NN cord-277665-ac8txr3h 187 15 , , , cord-277665-ac8txr3h 187 16 e.g. e.g. RB cord-277665-ac8txr3h 187 17 , , , cord-277665-ac8txr3h 187 18 DNA dna NN cord-277665-ac8txr3h 187 19 , , , cord-277665-ac8txr3h 187 20 antibody antibody NN cord-277665-ac8txr3h 187 21 , , , cord-277665-ac8txr3h 187 22 receptor receptor NN cord-277665-ac8txr3h 187 23 , , , cord-277665-ac8txr3h 187 24 or or CC cord-277665-ac8txr3h 187 25 enzyme enzyme NN cord-277665-ac8txr3h 187 26 , , , cord-277665-ac8txr3h 187 27 and and CC cord-277665-ac8txr3h 187 28 the the DT cord-277665-ac8txr3h 187 29 electrochemical electrochemical JJ cord-277665-ac8txr3h 187 30 , , , cord-277665-ac8txr3h 187 31 optical optical JJ cord-277665-ac8txr3h 187 32 , , , cord-277665-ac8txr3h 187 33 calorimetric calorimetric JJ cord-277665-ac8txr3h 187 34 , , , cord-277665-ac8txr3h 187 35 or or CC cord-277665-ac8txr3h 187 36 piezoelectric piezoelectric JJ cord-277665-ac8txr3h 187 37 transducer transducer NN cord-277665-ac8txr3h 187 38 that that WDT cord-277665-ac8txr3h 187 39 detects detect VBZ cord-277665-ac8txr3h 187 40 an an DT cord-277665-ac8txr3h 187 41 attach attach VB cord-277665-ac8txr3h 187 42 - - HYPH cord-277665-ac8txr3h 187 43 ment ment NN cord-277665-ac8txr3h 187 44 of of IN cord-277665-ac8txr3h 187 45 an an DT cord-277665-ac8txr3h 187 46 analyte analyte NN cord-277665-ac8txr3h 187 47 to to IN cord-277665-ac8txr3h 187 48 the the DT cord-277665-ac8txr3h 187 49 biorecognition biorecognition NN cord-277665-ac8txr3h 187 50 layer layer NN cord-277665-ac8txr3h 187 51 ( ( -LRB- cord-277665-ac8txr3h 187 52 Deisingh Deisingh NNP cord-277665-ac8txr3h 187 53 and and CC cord-277665-ac8txr3h 187 54 Thompson Thompson NNP cord-277665-ac8txr3h 187 55 , , , cord-277665-ac8txr3h 187 56 2004 2004 CD cord-277665-ac8txr3h 187 57 ) ) -RRB- cord-277665-ac8txr3h 187 58 . . . cord-277665-ac8txr3h 188 1 The the DT cord-277665-ac8txr3h 188 2 physiochemical physiochemical JJ cord-277665-ac8txr3h 188 3 properties property NNS cord-277665-ac8txr3h 188 4 that that WDT cord-277665-ac8txr3h 188 5 determine determine VBP cord-277665-ac8txr3h 188 6 the the DT cord-277665-ac8txr3h 188 7 analytical analytical JJ cord-277665-ac8txr3h 188 8 characteristics characteristic NNS cord-277665-ac8txr3h 188 9 of of IN cord-277665-ac8txr3h 188 10 biosensing biosense VBG cord-277665-ac8txr3h 188 11 devices device NNS cord-277665-ac8txr3h 188 12 are be VBP cord-277665-ac8txr3h 188 13 surface surface NN cord-277665-ac8txr3h 188 14 characteristics characteristic NNS cord-277665-ac8txr3h 188 15 of of IN cord-277665-ac8txr3h 188 16 the the DT cord-277665-ac8txr3h 188 17 sensing sensing NN cord-277665-ac8txr3h 188 18 area area NN cord-277665-ac8txr3h 188 19 and and CC cord-277665-ac8txr3h 188 20 its -PRON- PRP$ cord-277665-ac8txr3h 188 21 size size NN cord-277665-ac8txr3h 188 22 , , , cord-277665-ac8txr3h 188 23 as as RB cord-277665-ac8txr3h 188 24 well well RB cord-277665-ac8txr3h 188 25 as as IN cord-277665-ac8txr3h 188 26 intrinsic intrinsic JJ cord-277665-ac8txr3h 188 27 properties property NNS cord-277665-ac8txr3h 188 28 of of IN cord-277665-ac8txr3h 188 29 the the DT cord-277665-ac8txr3h 188 30 material material NN cord-277665-ac8txr3h 188 31 . . . cord-277665-ac8txr3h 189 1 In in IN cord-277665-ac8txr3h 189 2 the the DT cord-277665-ac8txr3h 189 3 past past JJ cord-277665-ac8txr3h 189 4 few few JJ cord-277665-ac8txr3h 189 5 years year NNS cord-277665-ac8txr3h 189 6 , , , cord-277665-ac8txr3h 189 7 significant significant JJ cord-277665-ac8txr3h 189 8 advances advance NNS cord-277665-ac8txr3h 189 9 have have VBP cord-277665-ac8txr3h 189 10 been be VBN cord-277665-ac8txr3h 189 11 made make VBN cord-277665-ac8txr3h 189 12 toward toward IN cord-277665-ac8txr3h 189 13 the the DT cord-277665-ac8txr3h 189 14 development development NN cord-277665-ac8txr3h 189 15 of of IN cord-277665-ac8txr3h 189 16 both both DT cord-277665-ac8txr3h 189 17 biosensors biosensor NNS cord-277665-ac8txr3h 189 18 and and CC cord-277665-ac8txr3h 189 19 biochips biochip NNS cord-277665-ac8txr3h 189 20 for for IN cord-277665-ac8txr3h 189 21 single single JJ cord-277665-ac8txr3h 189 22 - - HYPH cord-277665-ac8txr3h 189 23 cell cell NN cord-277665-ac8txr3h 189 24 analysis analysis NN cord-277665-ac8txr3h 189 25 , , , cord-277665-ac8txr3h 189 26 detecting detect VBG cord-277665-ac8txr3h 189 27 of of IN cord-277665-ac8txr3h 189 28 pathogens pathogen NNS cord-277665-ac8txr3h 189 29 and and CC cord-277665-ac8txr3h 189 30 toxins toxin NNS cord-277665-ac8txr3h 190 1 ( ( -LRB- cord-277665-ac8txr3h 190 2 Vo Vo NNP cord-277665-ac8txr3h 190 3 - - HYPH cord-277665-ac8txr3h 190 4 Dinh Dinh NNP cord-277665-ac8txr3h 190 5 et et NNP cord-277665-ac8txr3h 190 6 al al NNP cord-277665-ac8txr3h 190 7 . . NNP cord-277665-ac8txr3h 190 8 , , , cord-277665-ac8txr3h 190 9 2001 2001 CD cord-277665-ac8txr3h 190 10 ) ) -RRB- cord-277665-ac8txr3h 190 11 , , , cord-277665-ac8txr3h 190 12 and and CC cord-277665-ac8txr3h 190 13 other other JJ cord-277665-ac8txr3h 190 14 biological biological JJ cord-277665-ac8txr3h 190 15 and and CC cord-277665-ac8txr3h 190 16 medical medical JJ cord-277665-ac8txr3h 190 17 applications application NNS cord-277665-ac8txr3h 190 18 . . . cord-277665-ac8txr3h 191 1 Diamond diamond NN cord-277665-ac8txr3h 191 2 films film NNS cord-277665-ac8txr3h 191 3 occupy occupy VBP cord-277665-ac8txr3h 191 4 a a DT cord-277665-ac8txr3h 191 5 special special JJ cord-277665-ac8txr3h 191 6 place place NN cord-277665-ac8txr3h 191 7 as as IN cord-277665-ac8txr3h 191 8 an an DT cord-277665-ac8txr3h 191 9 electrode electrode JJ cord-277665-ac8txr3h 191 10 material material NN cord-277665-ac8txr3h 191 11 in in IN cord-277665-ac8txr3h 191 12 biosensors biosensor NNS cord-277665-ac8txr3h 191 13 . . . cord-277665-ac8txr3h 192 1 When when WRB cord-277665-ac8txr3h 192 2 made make VBN cord-277665-ac8txr3h 192 3 sufficiently sufficiently RB cord-277665-ac8txr3h 192 4 electrically electrically RB cord-277665-ac8txr3h 192 5 conducting conduct VBG cord-277665-ac8txr3h 192 6 by by IN cord-277665-ac8txr3h 192 7 boron boron NN cord-277665-ac8txr3h 192 8 doping doping NN cord-277665-ac8txr3h 192 9 , , , cord-277665-ac8txr3h 192 10 thin thin JJ cord-277665-ac8txr3h 192 11 - - HYPH cord-277665-ac8txr3h 192 12 film film NN cord-277665-ac8txr3h 192 13 and and CC cord-277665-ac8txr3h 192 14 free free RB cord-277665-ac8txr3h 192 15 - - HYPH cord-277665-ac8txr3h 192 16 standing stand VBG cord-277665-ac8txr3h 192 17 diamond diamond NN cord-277665-ac8txr3h 192 18 electrodes electrode NNS cord-277665-ac8txr3h 192 19 exhibit exhibit VBP cord-277665-ac8txr3h 192 20 remarkable remarkable JJ cord-277665-ac8txr3h 192 21 chemical chemical NN cord-277665-ac8txr3h 192 22 resistance resistance NN cord-277665-ac8txr3h 192 23 to to IN cord-277665-ac8txr3h 192 24 etching etching NN cord-277665-ac8txr3h 192 25 , , , cord-277665-ac8txr3h 192 26 a a DT cord-277665-ac8txr3h 192 27 wide wide JJ cord-277665-ac8txr3h 192 28 potential potential JJ cord-277665-ac8txr3h 192 29 window window NN cord-277665-ac8txr3h 192 30 , , , cord-277665-ac8txr3h 192 31 low low JJ cord-277665-ac8txr3h 192 32 background background NN cord-277665-ac8txr3h 192 33 current current JJ cord-277665-ac8txr3h 192 34 responses response NNS cord-277665-ac8txr3h 192 35 , , , cord-277665-ac8txr3h 192 36 mechanical mechanical JJ cord-277665-ac8txr3h 192 37 stability stability NN cord-277665-ac8txr3h 192 38 toward toward IN cord-277665-ac8txr3h 192 39 ultrasound ultrasound NN cord-277665-ac8txr3h 192 40 - - HYPH cord-277665-ac8txr3h 192 41 induced induce VBN cord-277665-ac8txr3h 192 42 interfacial interfacial JJ cord-277665-ac8txr3h 192 43 cavitation cavitation NN cord-277665-ac8txr3h 192 44 , , , cord-277665-ac8txr3h 192 45 a a DT cord-277665-ac8txr3h 192 46 low low JJ cord-277665-ac8txr3h 192 47 stickiness stickiness NN cord-277665-ac8txr3h 192 48 in in IN cord-277665-ac8txr3h 192 49 adsorption adsorption NN cord-277665-ac8txr3h 192 50 processes process NNS cord-277665-ac8txr3h 192 51 , , , cord-277665-ac8txr3h 192 52 and and CC cord-277665-ac8txr3h 192 53 a a DT cord-277665-ac8txr3h 192 54 high high JJ cord-277665-ac8txr3h 192 55 degree degree NN cord-277665-ac8txr3h 192 56 of of IN cord-277665-ac8txr3h 192 57 tunability tunability NN cord-277665-ac8txr3h 192 58 of of IN cord-277665-ac8txr3h 192 59 the the DT cord-277665-ac8txr3h 192 60 surface surface NN cord-277665-ac8txr3h 192 61 properties property NNS cord-277665-ac8txr3h 192 62 ( ( -LRB- cord-277665-ac8txr3h 192 63 reviewed review VBN cord-277665-ac8txr3h 192 64 by by IN cord-277665-ac8txr3h 192 65 Compton Compton NNP cord-277665-ac8txr3h 192 66 et et NNP cord-277665-ac8txr3h 192 67 al al NNP cord-277665-ac8txr3h 192 68 . . NNP cord-277665-ac8txr3h 192 69 , , , cord-277665-ac8txr3h 192 70 2003 2003 CD cord-277665-ac8txr3h 192 71 ) ) -RRB- cord-277665-ac8txr3h 192 72 . . . cord-277665-ac8txr3h 193 1 Tatsuma Tatsuma NNP cord-277665-ac8txr3h 193 2 et et FW cord-277665-ac8txr3h 193 3 al al NNP cord-277665-ac8txr3h 193 4 . . . cord-277665-ac8txr3h 194 1 ( ( -LRB- cord-277665-ac8txr3h 194 2 2000 2000 CD cord-277665-ac8txr3h 194 3 ) ) -RRB- cord-277665-ac8txr3h 194 4 have have VBP cord-277665-ac8txr3h 194 5 examined examine VBN cord-277665-ac8txr3h 194 6 direct direct JJ cord-277665-ac8txr3h 194 7 electron electron NN cord-277665-ac8txr3h 194 8 transfer transfer NN cord-277665-ac8txr3h 194 9 from from IN cord-277665-ac8txr3h 194 10 BDD BDD NNP cord-277665-ac8txr3h 194 11 electrodes electrode NNS cord-277665-ac8txr3h 194 12 to to IN cord-277665-ac8txr3h 194 13 heme heme NN cord-277665-ac8txr3h 194 14 peptide peptide NN cord-277665-ac8txr3h 194 15 and and CC cord-277665-ac8txr3h 194 16 horseradish horseradish NN cord-277665-ac8txr3h 194 17 peroxidase peroxidase NN cord-277665-ac8txr3h 194 18 for for IN cord-277665-ac8txr3h 194 19 the the DT cord-277665-ac8txr3h 194 20 application application NN cord-277665-ac8txr3h 194 21 to to IN cord-277665-ac8txr3h 194 22 H h NN cord-277665-ac8txr3h 194 23 2 2 CD cord-277665-ac8txr3h 194 24 O o NN cord-277665-ac8txr3h 194 25 2 2 CD cord-277665-ac8txr3h 194 26 biosensors biosensor NNS cord-277665-ac8txr3h 194 27 . . . cord-277665-ac8txr3h 195 1 Diamond diamond NN cord-277665-ac8txr3h 195 2 electrodes electrode NNS cord-277665-ac8txr3h 195 3 exhibit exhibit VBP cord-277665-ac8txr3h 195 4 low low JJ cord-277665-ac8txr3h 195 5 sensitivity sensitivity NN cord-277665-ac8txr3h 195 6 to to IN cord-277665-ac8txr3h 195 7 interfering interfere VBG cord-277665-ac8txr3h 195 8 agents agent NNS cord-277665-ac8txr3h 195 9 and and CC cord-277665-ac8txr3h 195 10 may may MD cord-277665-ac8txr3h 195 11 become become VB cord-277665-ac8txr3h 195 12 a a DT cord-277665-ac8txr3h 195 13 capable capable JJ cord-277665-ac8txr3h 195 14 H h NN cord-277665-ac8txr3h 195 15 2 2 CD cord-277665-ac8txr3h 195 16 O o NN cord-277665-ac8txr3h 195 17 2 2 CD cord-277665-ac8txr3h 195 18 biosensor biosensor NN cord-277665-ac8txr3h 195 19 . . . cord-277665-ac8txr3h 196 1 Nanocrystalline Nanocrystalline NNP cord-277665-ac8txr3h 196 2 diamond diamond NN cord-277665-ac8txr3h 196 3 films film NNS cord-277665-ac8txr3h 196 4 can can MD cord-277665-ac8txr3h 196 5 be be VB cord-277665-ac8txr3h 196 6 both both CC cord-277665-ac8txr3h 196 7 a a DT cord-277665-ac8txr3h 196 8 platform platform NN cord-277665-ac8txr3h 196 9 for for IN cord-277665-ac8txr3h 196 10 biofunctionalization biofunctionalization NN cord-277665-ac8txr3h 196 11 and and CC cord-277665-ac8txr3h 196 12 serve serve VB cord-277665-ac8txr3h 196 13 as as IN cord-277665-ac8txr3h 196 14 an an DT cord-277665-ac8txr3h 196 15 electrode electrode NN cord-277665-ac8txr3h 196 16 in in IN cord-277665-ac8txr3h 196 17 biosensors biosensor NNS cord-277665-ac8txr3h 196 18 based base VBN cord-277665-ac8txr3h 196 19 on on IN cord-277665-ac8txr3h 196 20 electrochemical electrochemical JJ cord-277665-ac8txr3h 196 21 reactions reaction NNS cord-277665-ac8txr3h 196 22 . . . cord-277665-ac8txr3h 197 1 Different different JJ cord-277665-ac8txr3h 197 2 proteins protein NNS cord-277665-ac8txr3h 197 3 can can MD cord-277665-ac8txr3h 197 4 be be VB cord-277665-ac8txr3h 197 5 covalently covalently RB cord-277665-ac8txr3h 197 6 attached attach VBN cord-277665-ac8txr3h 197 7 to to IN cord-277665-ac8txr3h 197 8 the the DT cord-277665-ac8txr3h 197 9 hydrogen hydrogen NN cord-277665-ac8txr3h 197 10 - - HYPH cord-277665-ac8txr3h 197 11 terminated terminate VBN cord-277665-ac8txr3h 197 12 nanocrystalline nanocrystalline NNP cord-277665-ac8txr3h 197 13 diamond diamond NN cord-277665-ac8txr3h 197 14 films film NNS cord-277665-ac8txr3h 197 15 modified modify VBN cord-277665-ac8txr3h 197 16 with with IN cord-277665-ac8txr3h 197 17 amino amino NN cord-277665-ac8txr3h 197 18 groups group NNS cord-277665-ac8txr3h 197 19 and and CC cord-277665-ac8txr3h 197 20 remain remain VBP cord-277665-ac8txr3h 197 21 fully fully RB cord-277665-ac8txr3h 197 22 functional functional JJ cord-277665-ac8txr3h 197 23 . . . cord-277665-ac8txr3h 198 1 Hartl Hartl NNP cord-277665-ac8txr3h 198 2 et et NNP cord-277665-ac8txr3h 198 3 al al NNP cord-277665-ac8txr3h 198 4 . . . cord-277665-ac8txr3h 199 1 ( ( -LRB- cord-277665-ac8txr3h 199 2 2004 2004 CD cord-277665-ac8txr3h 199 3 ) ) -RRB- cord-277665-ac8txr3h 199 4 functionalized functionalize VBN cord-277665-ac8txr3h 199 5 nanocrystalline nanocrystalline NNP cord-277665-ac8txr3h 199 6 diamond diamond NN cord-277665-ac8txr3h 199 7 electrodes electrode NNS cord-277665-ac8txr3h 199 8 with with IN cord-277665-ac8txr3h 199 9 catalase catalase NN cord-277665-ac8txr3h 199 10 and and CC cord-277665-ac8txr3h 199 11 detected detect VBD cord-277665-ac8txr3h 199 12 a a DT cord-277665-ac8txr3h 199 13 direct direct JJ cord-277665-ac8txr3h 199 14 electron electron NN cord-277665-ac8txr3h 199 15 transfer transfer NN cord-277665-ac8txr3h 199 16 between between IN cord-277665-ac8txr3h 199 17 the the DT cord-277665-ac8txr3h 199 18 redox redox NN cord-277665-ac8txr3h 199 19 centre centre NN cord-277665-ac8txr3h 199 20 of of IN cord-277665-ac8txr3h 199 21 the the DT cord-277665-ac8txr3h 199 22 enzyme enzyme NN cord-277665-ac8txr3h 199 23 and and CC cord-277665-ac8txr3h 199 24 the the DT cord-277665-ac8txr3h 199 25 diamond diamond NN cord-277665-ac8txr3h 199 26 electrode electrode NN cord-277665-ac8txr3h 199 27 . . . cord-277665-ac8txr3h 200 1 Also also RB cord-277665-ac8txr3h 200 2 , , , cord-277665-ac8txr3h 200 3 the the DT cord-277665-ac8txr3h 200 4 electrode electrode NN cord-277665-ac8txr3h 200 5 was be VBD cord-277665-ac8txr3h 200 6 found find VBN cord-277665-ac8txr3h 200 7 to to TO cord-277665-ac8txr3h 200 8 be be VB cord-277665-ac8txr3h 200 9 sensitive sensitive JJ cord-277665-ac8txr3h 200 10 to to IN cord-277665-ac8txr3h 200 11 hydrogen hydrogen NN cord-277665-ac8txr3h 200 12 peroxide peroxide NN cord-277665-ac8txr3h 200 13 . . . cord-277665-ac8txr3h 201 1 Hydrogenated hydrogenate VBN cord-277665-ac8txr3h 201 2 diamond diamond NN cord-277665-ac8txr3h 201 3 can can MD cord-277665-ac8txr3h 201 4 gain gain VB cord-277665-ac8txr3h 201 5 surface surface NN cord-277665-ac8txr3h 201 6 conductivity conductivity NN cord-277665-ac8txr3h 201 7 after after IN cord-277665-ac8txr3h 201 8 exposure exposure NN cord-277665-ac8txr3h 201 9 to to IN cord-277665-ac8txr3h 201 10 air air NN cord-277665-ac8txr3h 201 11 and and CC cord-277665-ac8txr3h 201 12 by by IN cord-277665-ac8txr3h 201 13 transfer transfer NN cord-277665-ac8txr3h 201 14 doping doping NN cord-277665-ac8txr3h 201 15 with with IN cord-277665-ac8txr3h 201 16 C C NNP cord-277665-ac8txr3h 201 17 60 60 CD cord-277665-ac8txr3h 201 18 resulting result VBG cord-277665-ac8txr3h 201 19 in in IN cord-277665-ac8txr3h 201 20 a a DT cord-277665-ac8txr3h 201 21 significant significant JJ cord-277665-ac8txr3h 201 22 rise rise NN cord-277665-ac8txr3h 201 23 in in IN cord-277665-ac8txr3h 201 24 two two CD cord-277665-ac8txr3h 201 25 - - HYPH cord-277665-ac8txr3h 201 26 dimensional dimensional JJ cord-277665-ac8txr3h 201 27 conductivity conductivity NN cord-277665-ac8txr3h 201 28 ( ( -LRB- cord-277665-ac8txr3h 201 29 Strobel Strobel NNP cord-277665-ac8txr3h 201 30 et et NNP cord-277665-ac8txr3h 201 31 al al NNP cord-277665-ac8txr3h 201 32 . . NNP cord-277665-ac8txr3h 201 33 , , , cord-277665-ac8txr3h 201 34 2004 2004 CD cord-277665-ac8txr3h 201 35 ) ) -RRB- cord-277665-ac8txr3h 201 36 . . . cord-277665-ac8txr3h 202 1 The the DT cord-277665-ac8txr3h 202 2 fully fully RB cord-277665-ac8txr3h 202 3 hydrogen hydrogen NN cord-277665-ac8txr3h 202 4 terminated terminate VBN cord-277665-ac8txr3h 202 5 diamond diamond NN cord-277665-ac8txr3h 202 6 surfaces surface NNS cord-277665-ac8txr3h 202 7 are be VBP cord-277665-ac8txr3h 202 8 not not RB cord-277665-ac8txr3h 202 9 pH ph NN cord-277665-ac8txr3h 202 10 sensitive sensitive JJ cord-277665-ac8txr3h 202 11 but but CC cord-277665-ac8txr3h 202 12 can can MD cord-277665-ac8txr3h 202 13 gain gain VB cord-277665-ac8txr3h 202 14 this this DT cord-277665-ac8txr3h 202 15 sensitivity sensitivity NN cord-277665-ac8txr3h 202 16 after after IN cord-277665-ac8txr3h 202 17 a a DT cord-277665-ac8txr3h 202 18 mild mild JJ cord-277665-ac8txr3h 202 19 surface surface NN cord-277665-ac8txr3h 202 20 oxidation oxidation NN cord-277665-ac8txr3h 202 21 by by IN cord-277665-ac8txr3h 202 22 ozone ozone NN cord-277665-ac8txr3h 202 23 ( ( -LRB- cord-277665-ac8txr3h 202 24 Garrido Garrido NNP cord-277665-ac8txr3h 202 25 et et NNP cord-277665-ac8txr3h 202 26 al al NNP cord-277665-ac8txr3h 202 27 . . NNP cord-277665-ac8txr3h 202 28 , , , cord-277665-ac8txr3h 202 29 2005 2005 CD cord-277665-ac8txr3h 202 30 ) ) -RRB- cord-277665-ac8txr3h 202 31 . . . cord-277665-ac8txr3h 203 1 The the DT cord-277665-ac8txr3h 203 2 difference difference NN cord-277665-ac8txr3h 203 3 in in IN cord-277665-ac8txr3h 203 4 DNA dna NN cord-277665-ac8txr3h 203 5 adsorption adsorption NN cord-277665-ac8txr3h 203 6 on on IN cord-277665-ac8txr3h 203 7 the the DT cord-277665-ac8txr3h 203 8 H H NNP cord-277665-ac8txr3h 203 9 - - HYPH cord-277665-ac8txr3h 203 10 and and CC cord-277665-ac8txr3h 203 11 O o NN cord-277665-ac8txr3h 203 12 - - HYPH cord-277665-ac8txr3h 203 13 terminated terminate VBN cord-277665-ac8txr3h 203 14 diamond diamond NN cord-277665-ac8txr3h 203 15 surfaces surface NNS cord-277665-ac8txr3h 203 16 may may MD cord-277665-ac8txr3h 203 17 be be VB cord-277665-ac8txr3h 203 18 useful useful JJ cord-277665-ac8txr3h 203 19 in in IN cord-277665-ac8txr3h 203 20 the the DT cord-277665-ac8txr3h 203 21 nanofabrication nanofabrication NN cord-277665-ac8txr3h 203 22 of of IN cord-277665-ac8txr3h 203 23 biosensors biosensor NNS cord-277665-ac8txr3h 203 24 . . . cord-277665-ac8txr3h 204 1 Compared compare VBN cord-277665-ac8txr3h 204 2 to to IN cord-277665-ac8txr3h 204 3 multiwalled multiwalled JJ cord-277665-ac8txr3h 204 4 carbon carbon NN cord-277665-ac8txr3h 204 5 nanotube nanotube NN cord-277665-ac8txr3h 204 6 - - HYPH cord-277665-ac8txr3h 204 7 based base VBN cord-277665-ac8txr3h 204 8 electrodes electrode NNS cord-277665-ac8txr3h 204 9 , , , cord-277665-ac8txr3h 204 10 BDD BDD NNP cord-277665-ac8txr3h 204 11 electrodes electrode NNS cord-277665-ac8txr3h 204 12 exhibit exhibit VBP cord-277665-ac8txr3h 204 13 less less RBR cord-277665-ac8txr3h 204 14 selective selective JJ cord-277665-ac8txr3h 204 15 voltammetric voltammetric JJ cord-277665-ac8txr3h 204 16 responses response NNS cord-277665-ac8txr3h 204 17 to to IN cord-277665-ac8txr3h 204 18 the the DT cord-277665-ac8txr3h 204 19 different different JJ cord-277665-ac8txr3h 204 20 biomolecules biomolecule NNS cord-277665-ac8txr3h 204 21 and and CC cord-277665-ac8txr3h 204 22 slower slow JJR cord-277665-ac8txr3h 204 23 electron electron NN cord-277665-ac8txr3h 204 24 - - HYPH cord-277665-ac8txr3h 204 25 transfer transfer NN cord-277665-ac8txr3h 204 26 kinetics kinetic NNS cord-277665-ac8txr3h 204 27 . . . cord-277665-ac8txr3h 205 1 BDD BDD NNP cord-277665-ac8txr3h 205 2 electrodes electrode NNS cord-277665-ac8txr3h 205 3 have have VBP cord-277665-ac8txr3h 205 4 no no DT cord-277665-ac8txr3h 205 5 intrinsic intrinsic JJ cord-277665-ac8txr3h 205 6 selective selective JJ cord-277665-ac8txr3h 205 7 response response NN cord-277665-ac8txr3h 205 8 to to IN cord-277665-ac8txr3h 205 9 L l NN cord-277665-ac8txr3h 205 10 - - HYPH cord-277665-ac8txr3h 205 11 ascorbic ascorbic NN cord-277665-ac8txr3h 205 12 acid acid NN cord-277665-ac8txr3h 205 13 , , , cord-277665-ac8txr3h 205 14 and and CC cord-277665-ac8txr3h 205 15 surface surface NN cord-277665-ac8txr3h 205 16 modification modification NN cord-277665-ac8txr3h 205 17 by by IN cord-277665-ac8txr3h 205 18 anodic anodic JJ cord-277665-ac8txr3h 205 19 polarization polarization NN cord-277665-ac8txr3h 205 20 is be VBZ cord-277665-ac8txr3h 205 21 required require VBN cord-277665-ac8txr3h 205 22 to to TO cord-277665-ac8txr3h 205 23 resolve resolve VB cord-277665-ac8txr3h 205 24 L l NN cord-277665-ac8txr3h 205 25 - - HYPH cord-277665-ac8txr3h 205 26 ascorbic ascorbic NN cord-277665-ac8txr3h 205 27 acid acid NN cord-277665-ac8txr3h 205 28 and and CC cord-277665-ac8txr3h 205 29 dopamine dopamine NN cord-277665-ac8txr3h 205 30 ( ( -LRB- cord-277665-ac8txr3h 205 31 Poh Poh NNP cord-277665-ac8txr3h 205 32 et et NNP cord-277665-ac8txr3h 205 33 al al NNP cord-277665-ac8txr3h 205 34 . . NNP cord-277665-ac8txr3h 205 35 , , , cord-277665-ac8txr3h 205 36 2004 2004 CD cord-277665-ac8txr3h 205 37 ) ) -RRB- cord-277665-ac8txr3h 205 38 . . . cord-277665-ac8txr3h 206 1 Highly highly RB cord-277665-ac8txr3h 206 2 conductive conductive JJ cord-277665-ac8txr3h 206 3 BDD BDD NNP cord-277665-ac8txr3h 206 4 electrodes electrode NNS cord-277665-ac8txr3h 206 5 are be VBP cord-277665-ac8txr3h 206 6 especially especially RB cord-277665-ac8txr3h 206 7 suited suit VBN cord-277665-ac8txr3h 206 8 for for IN cord-277665-ac8txr3h 206 9 electrochemical electrochemical JJ cord-277665-ac8txr3h 206 10 detection detection NN cord-277665-ac8txr3h 206 11 of of IN cord-277665-ac8txr3h 206 12 nucleic nucleic JJ cord-277665-ac8txr3h 206 13 acids acid NNS cord-277665-ac8txr3h 206 14 in in IN cord-277665-ac8txr3h 206 15 aqueous aqueous JJ cord-277665-ac8txr3h 206 16 solutions solution NNS cord-277665-ac8txr3h 206 17 . . . cord-277665-ac8txr3h 207 1 Their -PRON- PRP$ cord-277665-ac8txr3h 207 2 distinctive distinctive JJ cord-277665-ac8txr3h 207 3 features feature NNS cord-277665-ac8txr3h 207 4 are be VBP cord-277665-ac8txr3h 207 5 high high JJ cord-277665-ac8txr3h 207 6 reproducibility reproducibility NN cord-277665-ac8txr3h 207 7 , , , cord-277665-ac8txr3h 207 8 small small JJ cord-277665-ac8txr3h 207 9 background background NN cord-277665-ac8txr3h 207 10 currents current NNS cord-277665-ac8txr3h 207 11 at at IN cord-277665-ac8txr3h 207 12 high high JJ cord-277665-ac8txr3h 207 13 positive positive JJ cord-277665-ac8txr3h 207 14 potentials potential NNS cord-277665-ac8txr3h 207 15 , , , cord-277665-ac8txr3h 207 16 and and CC cord-277665-ac8txr3h 207 17 robustness robustness NN cord-277665-ac8txr3h 207 18 under under IN cord-277665-ac8txr3h 207 19 extreme extreme JJ cord-277665-ac8txr3h 207 20 conditions condition NNS cord-277665-ac8txr3h 208 1 ( ( -LRB- cord-277665-ac8txr3h 208 2 Prado Prado NNP cord-277665-ac8txr3h 208 3 et et FW cord-277665-ac8txr3h 208 4 al al NNP cord-277665-ac8txr3h 208 5 . . NNP cord-277665-ac8txr3h 208 6 , , , cord-277665-ac8txr3h 208 7 2002 2002 CD cord-277665-ac8txr3h 208 8 ) ) -RRB- cord-277665-ac8txr3h 208 9 . . . cord-277665-ac8txr3h 209 1 Importantly importantly RB cord-277665-ac8txr3h 209 2 , , , cord-277665-ac8txr3h 209 3 BDD BDD NNP cord-277665-ac8txr3h 209 4 electrodes electrode NNS cord-277665-ac8txr3h 209 5 can can MD cord-277665-ac8txr3h 209 6 be be VB cord-277665-ac8txr3h 209 7 used use VBN cord-277665-ac8txr3h 209 8 in in IN cord-277665-ac8txr3h 209 9 analysis analysis NN cord-277665-ac8txr3h 209 10 involving involve VBG cord-277665-ac8txr3h 209 11 a a DT cord-277665-ac8txr3h 209 12 heating heating NN cord-277665-ac8txr3h 209 13 step step NN cord-277665-ac8txr3h 209 14 and and CC cord-277665-ac8txr3h 209 15 ultrasonic ultrasonic JJ cord-277665-ac8txr3h 209 16 treatment treatment NN cord-277665-ac8txr3h 209 17 . . . cord-277665-ac8txr3h 210 1 Well well RB cord-277665-ac8txr3h 210 2 - - HYPH cord-277665-ac8txr3h 210 3 defined define VBN cord-277665-ac8txr3h 210 4 peaks peak NNS cord-277665-ac8txr3h 210 5 , , , cord-277665-ac8txr3h 210 6 observed observe VBD cord-277665-ac8txr3h 210 7 with with IN cord-277665-ac8txr3h 210 8 tRNA tRNA NNP cord-277665-ac8txr3h 210 9 , , , cord-277665-ac8txr3h 210 10 single single JJ cord-277665-ac8txr3h 210 11 - - HYPH cord-277665-ac8txr3h 210 12 and and CC cord-277665-ac8txr3h 210 13 double double RB cord-277665-ac8txr3h 210 14 - - HYPH cord-277665-ac8txr3h 210 15 stranded stranded JJ cord-277665-ac8txr3h 210 16 DNA dna NN cord-277665-ac8txr3h 210 17 , , , cord-277665-ac8txr3h 210 18 and and CC cord-277665-ac8txr3h 210 19 2′deoxyguanosine 2′deoxyguanosine CD cord-277665-ac8txr3h 210 20 5′-monophosphate 5′-monophosphate CD cord-277665-ac8txr3h 210 21 were be VBD cord-277665-ac8txr3h 210 22 directly directly RB cord-277665-ac8txr3h 210 23 assignable assignable JJ cord-277665-ac8txr3h 210 24 to to IN cord-277665-ac8txr3h 210 25 the the DT cord-277665-ac8txr3h 210 26 electrooxidation electrooxidation NN cord-277665-ac8txr3h 210 27 of of IN cord-277665-ac8txr3h 210 28 deoxyguanosine deoxyguanosine NNP cord-277665-ac8txr3h 210 29 monophosphate monophosphate NNP cord-277665-ac8txr3h 211 1 ( ( -LRB- cord-277665-ac8txr3h 211 2 Prado Prado NNP cord-277665-ac8txr3h 211 3 et et FW cord-277665-ac8txr3h 211 4 al al NNP cord-277665-ac8txr3h 211 5 . . NNP cord-277665-ac8txr3h 211 6 , , , cord-277665-ac8txr3h 211 7 2002 2002 CD cord-277665-ac8txr3h 211 8 ) ) -RRB- cord-277665-ac8txr3h 211 9 . . . cord-277665-ac8txr3h 212 1 Polycrystalline polycrystalline JJ cord-277665-ac8txr3h 212 2 diamond diamond NN cord-277665-ac8txr3h 212 3 films film NNS cord-277665-ac8txr3h 212 4 deposited deposit VBN cord-277665-ac8txr3h 212 5 by by IN cord-277665-ac8txr3h 212 6 microwave microwave NN cord-277665-ac8txr3h 212 7 plasma plasma NN cord-277665-ac8txr3h 212 8 CVD CVD NNP cord-277665-ac8txr3h 212 9 were be VBD cord-277665-ac8txr3h 212 10 incorporated incorporate VBN cord-277665-ac8txr3h 212 11 in in IN cord-277665-ac8txr3h 212 12 the the DT cord-277665-ac8txr3h 212 13 design design NN cord-277665-ac8txr3h 212 14 of of IN cord-277665-ac8txr3h 212 15 four four CD cord-277665-ac8txr3h 212 16 different different JJ cord-277665-ac8txr3h 212 17 glucose glucose NN cord-277665-ac8txr3h 212 18 sensors sensor NNS cord-277665-ac8txr3h 212 19 by by IN cord-277665-ac8txr3h 212 20 Troupe Troupe NNP cord-277665-ac8txr3h 212 21 et et NNP cord-277665-ac8txr3h 212 22 al al NNP cord-277665-ac8txr3h 212 23 . . . cord-277665-ac8txr3h 213 1 ( ( -LRB- cord-277665-ac8txr3h 213 2 1998 1998 CD cord-277665-ac8txr3h 213 3 ) ) -RRB- cord-277665-ac8txr3h 213 4 . . . cord-277665-ac8txr3h 214 1 While while IN cord-277665-ac8txr3h 214 2 a a DT cord-277665-ac8txr3h 214 3 diamond diamond NN cord-277665-ac8txr3h 214 4 - - HYPH cord-277665-ac8txr3h 214 5 platinum platinum NN cord-277665-ac8txr3h 214 6 - - HYPH cord-277665-ac8txr3h 214 7 glucose glucose NN cord-277665-ac8txr3h 214 8 oxidase oxidase NN cord-277665-ac8txr3h 214 9 sensor sensor NN cord-277665-ac8txr3h 214 10 was be VBD cord-277665-ac8txr3h 214 11 affected affect VBN cord-277665-ac8txr3h 214 12 by by IN cord-277665-ac8txr3h 214 13 the the DT cord-277665-ac8txr3h 214 14 presence presence NN cord-277665-ac8txr3h 214 15 of of IN cord-277665-ac8txr3h 214 16 electroactive electroactive JJ cord-277665-ac8txr3h 214 17 chemicals chemical NNS cord-277665-ac8txr3h 214 18 in in IN cord-277665-ac8txr3h 214 19 blood blood NN cord-277665-ac8txr3h 214 20 , , , cord-277665-ac8txr3h 214 21 usage usage NN cord-277665-ac8txr3h 214 22 of of IN cord-277665-ac8txr3h 214 23 BDD BDD NNP cord-277665-ac8txr3h 214 24 as as IN cord-277665-ac8txr3h 214 25 a a DT cord-277665-ac8txr3h 214 26 conducting conduct VBG cord-277665-ac8txr3h 214 27 electrode electrode NN cord-277665-ac8txr3h 214 28 in in IN cord-277665-ac8txr3h 214 29 place place NN cord-277665-ac8txr3h 214 30 of of IN cord-277665-ac8txr3h 214 31 the the DT cord-277665-ac8txr3h 214 32 platinum platinum NN cord-277665-ac8txr3h 214 33 provided provide VBD cord-277665-ac8txr3h 214 34 a a DT cord-277665-ac8txr3h 214 35 strong strong JJ cord-277665-ac8txr3h 214 36 and and CC cord-277665-ac8txr3h 214 37 repeatable repeatable JJ cord-277665-ac8txr3h 214 38 response response NN cord-277665-ac8txr3h 214 39 to to IN cord-277665-ac8txr3h 214 40 glucose glucose NN cord-277665-ac8txr3h 214 41 . . . cord-277665-ac8txr3h 215 1 The the DT cord-277665-ac8txr3h 215 2 sensor sensor NN cord-277665-ac8txr3h 215 3 that that WDT cord-277665-ac8txr3h 215 4 was be VBD cord-277665-ac8txr3h 215 5 fabricated fabricate VBN cord-277665-ac8txr3h 215 6 with with IN cord-277665-ac8txr3h 215 7 the the DT cord-277665-ac8txr3h 215 8 surface surface NN cord-277665-ac8txr3h 215 9 - - HYPH cord-277665-ac8txr3h 215 10 modified modify VBN cord-277665-ac8txr3h 215 11 diamond diamond NN cord-277665-ac8txr3h 215 12 allowed allow VBN cord-277665-ac8txr3h 215 13 attachment attachment NN cord-277665-ac8txr3h 215 14 of of IN cord-277665-ac8txr3h 215 15 biologically biologically RB cord-277665-ac8txr3h 215 16 active active JJ cord-277665-ac8txr3h 215 17 molecules molecule NNS cord-277665-ac8txr3h 215 18 and and CC cord-277665-ac8txr3h 215 19 electron electron NN cord-277665-ac8txr3h 215 20 transfer transfer NN cord-277665-ac8txr3h 215 21 from from IN cord-277665-ac8txr3h 215 22 glucose glucose NN cord-277665-ac8txr3h 215 23 oxidase oxidase NN cord-277665-ac8txr3h 215 24 to to IN cord-277665-ac8txr3h 215 25 the the DT cord-277665-ac8txr3h 215 26 electrode electrode NN cord-277665-ac8txr3h 215 27 . . . cord-277665-ac8txr3h 216 1 This this DT cord-277665-ac8txr3h 216 2 approach approach NN cord-277665-ac8txr3h 216 3 received receive VBD cord-277665-ac8txr3h 216 4 further further JJ cord-277665-ac8txr3h 216 5 development development NN cord-277665-ac8txr3h 216 6 in in IN cord-277665-ac8txr3h 216 7 a a DT cord-277665-ac8txr3h 216 8 study study NN cord-277665-ac8txr3h 216 9 by by IN cord-277665-ac8txr3h 216 10 . . . cord-277665-ac8txr3h 217 1 However however RB cord-277665-ac8txr3h 217 2 , , , cord-277665-ac8txr3h 217 3 a a DT cord-277665-ac8txr3h 217 4 3,3′-diaminobenzidine 3,3′-diaminobenzidine NNP cord-277665-ac8txr3h 217 5 - - HYPH cord-277665-ac8txr3h 217 6 electropolymerized electropolymerize VBN cord-277665-ac8txr3h 217 7 carbon carbon NN cord-277665-ac8txr3h 217 8 nanotube nanotube NN cord-277665-ac8txr3h 217 9 - - HYPH cord-277665-ac8txr3h 217 10 based base VBN cord-277665-ac8txr3h 217 11 electrode electrode NN cord-277665-ac8txr3h 217 12 outperformed outperform VBD cord-277665-ac8txr3h 217 13 the the DT cord-277665-ac8txr3h 217 14 diamond diamond NN cord-277665-ac8txr3h 217 15 one one CD cord-277665-ac8txr3h 217 16 in in IN cord-277665-ac8txr3h 217 17 terms term NNS cord-277665-ac8txr3h 217 18 of of IN cord-277665-ac8txr3h 217 19 selectivity selectivity NN cord-277665-ac8txr3h 217 20 and and CC cord-277665-ac8txr3h 217 21 sensitivity sensitivity NN cord-277665-ac8txr3h 217 22 . . . cord-277665-ac8txr3h 218 1 In in IN cord-277665-ac8txr3h 218 2 another another DT cord-277665-ac8txr3h 218 3 attempt attempt NN cord-277665-ac8txr3h 218 4 to to TO cord-277665-ac8txr3h 218 5 develop develop VB cord-277665-ac8txr3h 218 6 a a DT cord-277665-ac8txr3h 218 7 ND ND NNP cord-277665-ac8txr3h 218 8 - - HYPH cord-277665-ac8txr3h 218 9 based base VBN cord-277665-ac8txr3h 218 10 biosensor biosensor NN cord-277665-ac8txr3h 218 11 immobilized immobilize VBD cord-277665-ac8txr3h 218 12 polyclonal polyclonal JJ cord-277665-ac8txr3h 218 13 antibodies antibody NNS cord-277665-ac8txr3h 218 14 against against IN cord-277665-ac8txr3h 218 15 Salmonella Salmonella NNP cord-277665-ac8txr3h 218 16 typhimurium typhimurium NN cord-277665-ac8txr3h 218 17 and and CC cord-277665-ac8txr3h 218 18 Staphylococcus Staphylococcus NNP cord-277665-ac8txr3h 218 19 aureus aureus NN cord-277665-ac8txr3h 218 20 on on IN cord-277665-ac8txr3h 218 21 nanocrystalline nanocrystalline NNP cord-277665-ac8txr3h 218 22 diamond diamond NNP cord-277665-ac8txr3h 218 23 films film NNS cord-277665-ac8txr3h 218 24 and and CC cord-277665-ac8txr3h 218 25 evaluated evaluate VBD cord-277665-ac8txr3h 218 26 the the DT cord-277665-ac8txr3h 218 27 efficacy efficacy NN cord-277665-ac8txr3h 218 28 of of IN cord-277665-ac8txr3h 218 29 immobilization immobilization NN cord-277665-ac8txr3h 218 30 by by IN cord-277665-ac8txr3h 218 31 enzymelinked enzymelinked JJ cord-277665-ac8txr3h 218 32 immunosorbent immunosorbent JJ cord-277665-ac8txr3h 218 33 assay assay NN cord-277665-ac8txr3h 218 34 ( ( -LRB- cord-277665-ac8txr3h 218 35 ELISA ELISA NNP cord-277665-ac8txr3h 218 36 ) ) -RRB- cord-277665-ac8txr3h 218 37 . . . cord-277665-ac8txr3h 219 1 The the DT cord-277665-ac8txr3h 219 2 immobilization immobilization NN cord-277665-ac8txr3h 219 3 of of IN cord-277665-ac8txr3h 219 4 antibodies antibody NNS cord-277665-ac8txr3h 219 5 and and CC cord-277665-ac8txr3h 219 6 attachment attachment NN cord-277665-ac8txr3h 219 7 of of IN cord-277665-ac8txr3h 219 8 bacteria bacteria NNS cord-277665-ac8txr3h 219 9 measured measure VBN cord-277665-ac8txr3h 219 10 by by IN cord-277665-ac8txr3h 219 11 SEM SEM NNP cord-277665-ac8txr3h 219 12 were be VBD cord-277665-ac8txr3h 219 13 more more RBR cord-277665-ac8txr3h 219 14 efficient efficient JJ cord-277665-ac8txr3h 219 15 on on IN cord-277665-ac8txr3h 219 16 a a DT cord-277665-ac8txr3h 219 17 surface surface NN cord-277665-ac8txr3h 219 18 of of IN cord-277665-ac8txr3h 219 19 air air NN cord-277665-ac8txr3h 219 20 plasma plasma NN cord-277665-ac8txr3h 219 21 - - HYPH cord-277665-ac8txr3h 219 22 treated treat VBN cord-277665-ac8txr3h 219 23 diamond diamond NN cord-277665-ac8txr3h 219 24 than than IN cord-277665-ac8txr3h 219 25 on on IN cord-277665-ac8txr3h 219 26 a a DT cord-277665-ac8txr3h 219 27 surface surface NN cord-277665-ac8txr3h 219 28 of of IN cord-277665-ac8txr3h 219 29 diamond diamond NN cord-277665-ac8txr3h 219 30 treated treat VBN cord-277665-ac8txr3h 219 31 preliminarily preliminarily RB cord-277665-ac8txr3h 219 32 with with IN cord-277665-ac8txr3h 219 33 the the DT cord-277665-ac8txr3h 219 34 hydrogen hydrogen NN cord-277665-ac8txr3h 219 35 plasma plasma NN cord-277665-ac8txr3h 219 36 . . . cord-277665-ac8txr3h 220 1 The the DT cord-277665-ac8txr3h 220 2 plasma plasma NN cord-277665-ac8txr3h 220 3 - - HYPH cord-277665-ac8txr3h 220 4 oxidized oxidize VBN cord-277665-ac8txr3h 220 5 surface surface NN cord-277665-ac8txr3h 220 6 of of IN cord-277665-ac8txr3h 220 7 ND ND NNP cord-277665-ac8txr3h 220 8 was be VBD cord-277665-ac8txr3h 220 9 more more RBR cord-277665-ac8txr3h 220 10 hydrophilic hydrophilic JJ cord-277665-ac8txr3h 220 11 and and CC cord-277665-ac8txr3h 220 12 was be VBD cord-277665-ac8txr3h 220 13 terminated terminate VBN cord-277665-ac8txr3h 220 14 with with IN cord-277665-ac8txr3h 220 15 hydroxyl hydroxyl NN cord-277665-ac8txr3h 220 16 and and CC cord-277665-ac8txr3h 220 17 carbonyl carbonyl NN cord-277665-ac8txr3h 220 18 groups group NNS cord-277665-ac8txr3h 220 19 . . . cord-277665-ac8txr3h 221 1 Modified modify VBN cord-277665-ac8txr3h 221 2 ND ND NNP cord-277665-ac8txr3h 221 3 particles particle NNS cord-277665-ac8txr3h 221 4 and and CC cord-277665-ac8txr3h 221 5 films film NNS cord-277665-ac8txr3h 221 6 have have VBP cord-277665-ac8txr3h 221 7 been be VBN cord-277665-ac8txr3h 221 8 used use VBN cord-277665-ac8txr3h 221 9 in in IN cord-277665-ac8txr3h 221 10 heterogeneous heterogeneous JJ cord-277665-ac8txr3h 221 11 and and CC cord-277665-ac8txr3h 221 12 electrochemical electrochemical JJ cord-277665-ac8txr3h 221 13 oxidation oxidation NN cord-277665-ac8txr3h 221 14 catalyses catalyse VBZ cord-277665-ac8txr3h 221 15 and and CC cord-277665-ac8txr3h 221 16 related related JJ cord-277665-ac8txr3h 221 17 applications application NNS cord-277665-ac8txr3h 221 18 , , , cord-277665-ac8txr3h 221 19 and and CC cord-277665-ac8txr3h 221 20 in in IN cord-277665-ac8txr3h 221 21 electrochemical electrochemical JJ cord-277665-ac8txr3h 221 22 analysis analysis NN cord-277665-ac8txr3h 221 23 ( ( -LRB- cord-277665-ac8txr3h 221 24 Bogatyreva Bogatyreva NNP cord-277665-ac8txr3h 221 25 et et NNP cord-277665-ac8txr3h 221 26 al al NNP cord-277665-ac8txr3h 221 27 . . NNP cord-277665-ac8txr3h 221 28 , , , cord-277665-ac8txr3h 221 29 2004 2004 CD cord-277665-ac8txr3h 222 1 ; ; : cord-277665-ac8txr3h 222 2 Song Song NNP cord-277665-ac8txr3h 222 3 et et FW cord-277665-ac8txr3h 222 4 al al NNP cord-277665-ac8txr3h 222 5 . . NNP cord-277665-ac8txr3h 222 6 , , , cord-277665-ac8txr3h 222 7 2004 2004 CD cord-277665-ac8txr3h 222 8 ; ; : cord-277665-ac8txr3h 222 9 Yang Yang NNP cord-277665-ac8txr3h 222 10 et et NNP cord-277665-ac8txr3h 222 11 al al NNP cord-277665-ac8txr3h 222 12 . . NNP cord-277665-ac8txr3h 222 13 , , , cord-277665-ac8txr3h 222 14 2005 2005 CD cord-277665-ac8txr3h 222 15 ) ) -RRB- cord-277665-ac8txr3h 222 16 . . . cord-277665-ac8txr3h 223 1 Using use VBG cord-277665-ac8txr3h 223 2 the the DT cord-277665-ac8txr3h 223 3 new new JJ cord-277665-ac8txr3h 223 4 amperometric amperometric JJ cord-277665-ac8txr3h 223 5 biosensors biosensor NNS cord-277665-ac8txr3h 223 6 designed design VBN cord-277665-ac8txr3h 223 7 with with IN cord-277665-ac8txr3h 223 8 monocrystalline monocrystalline JJ cord-277665-ac8txr3h 223 9 diamond diamond NN cord-277665-ac8txr3h 223 10 and and CC cord-277665-ac8txr3h 223 11 L l NN cord-277665-ac8txr3h 223 12 - - : cord-277665-ac8txr3h 223 13 and and CC cord-277665-ac8txr3h 223 14 D d NN cord-277665-ac8txr3h 223 15 - - HYPH cord-277665-ac8txr3h 223 16 amino amino NN cord-277665-ac8txr3h 223 17 acid acid NN cord-277665-ac8txr3h 223 18 oxidases oxidase NNS cord-277665-ac8txr3h 223 19 , , , cord-277665-ac8txr3h 223 20 Stefan Stefan NNP cord-277665-ac8txr3h 223 21 et et NNP cord-277665-ac8txr3h 223 22 al al NNP cord-277665-ac8txr3h 223 23 . . . cord-277665-ac8txr3h 224 1 ( ( -LRB- cord-277665-ac8txr3h 224 2 2004 2004 CD cord-277665-ac8txr3h 224 3 ) ) -RRB- cord-277665-ac8txr3h 224 4 conducted conduct VBN cord-277665-ac8txr3h 224 5 differential differential JJ cord-277665-ac8txr3h 224 6 pulse pulse NN cord-277665-ac8txr3h 224 7 voltammetric voltammetric JJ cord-277665-ac8txr3h 224 8 assay assay NN cord-277665-ac8txr3h 224 9 of of IN cord-277665-ac8txr3h 224 10 L L NNP cord-277665-ac8txr3h 224 11 - - HYPH cord-277665-ac8txr3h 224 12 pipecolic pipecolic NNP cord-277665-ac8txr3h 224 13 and and CC cord-277665-ac8txr3h 224 14 D D NNP cord-277665-ac8txr3h 224 15 - - HYPH cord-277665-ac8txr3h 224 16 pipecolic pipecolic JJ cord-277665-ac8txr3h 224 17 acids acid NNS cord-277665-ac8txr3h 224 18 in in IN cord-277665-ac8txr3h 224 19 serum serum NN cord-277665-ac8txr3h 224 20 samples sample NNS cord-277665-ac8txr3h 224 21 with with IN cord-277665-ac8txr3h 224 22 a a DT cord-277665-ac8txr3h 224 23 low low JJ cord-277665-ac8txr3h 224 24 limit limit NN cord-277665-ac8txr3h 224 25 of of IN cord-277665-ac8txr3h 224 26 detection detection NN cord-277665-ac8txr3h 224 27 . . . cord-277665-ac8txr3h 225 1 The the DT cord-277665-ac8txr3h 225 2 impedance impedance NN cord-277665-ac8txr3h 225 3 of of IN cord-277665-ac8txr3h 225 4 the the DT cord-277665-ac8txr3h 225 5 diamond diamond NN cord-277665-ac8txr3h 225 6 film film NN cord-277665-ac8txr3h 225 7 can can MD cord-277665-ac8txr3h 225 8 be be VB cord-277665-ac8txr3h 225 9 affected affect VBN cord-277665-ac8txr3h 225 10 by by IN cord-277665-ac8txr3h 225 11 DNA dna NN cord-277665-ac8txr3h 225 12 hybridization hybridization NN cord-277665-ac8txr3h 225 13 at at IN cord-277665-ac8txr3h 225 14 the the DT cord-277665-ac8txr3h 225 15 interface interface NN cord-277665-ac8txr3h 225 16 that that WDT cord-277665-ac8txr3h 225 17 induces induce VBZ cord-277665-ac8txr3h 225 18 a a DT cord-277665-ac8txr3h 225 19 field field NN cord-277665-ac8txr3h 225 20 effect effect NN cord-277665-ac8txr3h 225 21 in in IN cord-277665-ac8txr3h 225 22 the the DT cord-277665-ac8txr3h 225 23 diamond diamond NN cord-277665-ac8txr3h 225 24 space space NN cord-277665-ac8txr3h 225 25 - - HYPH cord-277665-ac8txr3h 225 26 charge charge NN cord-277665-ac8txr3h 225 27 layer layer NN cord-277665-ac8txr3h 225 28 . . . cord-277665-ac8txr3h 226 1 By by IN cord-277665-ac8txr3h 226 2 identifying identify VBG cord-277665-ac8txr3h 226 3 a a DT cord-277665-ac8txr3h 226 4 range range NN cord-277665-ac8txr3h 226 5 of of IN cord-277665-ac8txr3h 226 6 impedances impedance NNS cord-277665-ac8txr3h 226 7 , , , cord-277665-ac8txr3h 226 8 where where WRB cord-277665-ac8txr3h 226 9 the the DT cord-277665-ac8txr3h 226 10 impedance impedance NN cord-277665-ac8txr3h 226 11 is be VBZ cord-277665-ac8txr3h 226 12 dominated dominate VBN cord-277665-ac8txr3h 226 13 by by IN cord-277665-ac8txr3h 226 14 the the DT cord-277665-ac8txr3h 226 15 diamond diamond NN cord-277665-ac8txr3h 226 16 space space NN cord-277665-ac8txr3h 226 17 - - HYPH cord-277665-ac8txr3h 226 18 charge charge NN cord-277665-ac8txr3h 226 19 layer layer NN cord-277665-ac8txr3h 226 20 , , , cord-277665-ac8txr3h 226 21 and and CC cord-277665-ac8txr3h 226 22 measuring measure VBG cord-277665-ac8txr3h 226 23 the the DT cord-277665-ac8txr3h 226 24 interfacial interfacial JJ cord-277665-ac8txr3h 226 25 impedance impedance NN cord-277665-ac8txr3h 226 26 , , , cord-277665-ac8txr3h 226 27 it -PRON- PRP cord-277665-ac8txr3h 226 28 is be VBZ cord-277665-ac8txr3h 226 29 possible possible JJ cord-277665-ac8txr3h 226 30 to to TO cord-277665-ac8txr3h 226 31 directly directly RB cord-277665-ac8txr3h 226 32 monitor monitor VB cord-277665-ac8txr3h 226 33 DNA dna NN cord-277665-ac8txr3h 226 34 hybridization hybridization NN cord-277665-ac8txr3h 226 35 . . . cord-277665-ac8txr3h 227 1 No no DT cord-277665-ac8txr3h 227 2 DNA dna NN cord-277665-ac8txr3h 227 3 labeling labeling NN cord-277665-ac8txr3h 227 4 is be VBZ cord-277665-ac8txr3h 227 5 required require VBN cord-277665-ac8txr3h 227 6 . . . cord-277665-ac8txr3h 228 1 Frequency frequency NN cord-277665-ac8txr3h 228 2 - - HYPH cord-277665-ac8txr3h 228 3 dependent dependent JJ cord-277665-ac8txr3h 228 4 interfacial interfacial JJ cord-277665-ac8txr3h 228 5 electrical electrical JJ cord-277665-ac8txr3h 228 6 properties property NNS cord-277665-ac8txr3h 228 7 of of IN cord-277665-ac8txr3h 228 8 nanocrystalline nanocrystalline NNP cord-277665-ac8txr3h 228 9 diamond diamond NNP cord-277665-ac8txr3h 228 10 films film NNS cord-277665-ac8txr3h 228 11 that that WDT cord-277665-ac8txr3h 228 12 were be VBD cord-277665-ac8txr3h 228 13 covalently covalently RB cord-277665-ac8txr3h 228 14 linked link VBN cord-277665-ac8txr3h 228 15 to to IN cord-277665-ac8txr3h 228 16 DNA dna NN cord-277665-ac8txr3h 228 17 oligonucleotides oligonucleotide NNS cord-277665-ac8txr3h 228 18 were be VBD cord-277665-ac8txr3h 228 19 changed change VBN cord-277665-ac8txr3h 228 20 significantly significantly RB cord-277665-ac8txr3h 228 21 in in IN cord-277665-ac8txr3h 228 22 the the DT cord-277665-ac8txr3h 228 23 presence presence NN cord-277665-ac8txr3h 228 24 of of IN cord-277665-ac8txr3h 228 25 complementary complementary JJ cord-277665-ac8txr3h 228 26 DNA dna NN cord-277665-ac8txr3h 228 27 oligonucleotides oligonucleotide NNS cord-277665-ac8txr3h 228 28 , , , cord-277665-ac8txr3h 228 29 with with IN cord-277665-ac8txr3h 228 30 only only JJ cord-277665-ac8txr3h 228 31 minimal minimal JJ cord-277665-ac8txr3h 228 32 changes change NNS cord-277665-ac8txr3h 228 33 due due IN cord-277665-ac8txr3h 228 34 to to IN cord-277665-ac8txr3h 228 35 the the DT cord-277665-ac8txr3h 228 36 presence presence NN cord-277665-ac8txr3h 228 37 of of IN cord-277665-ac8txr3h 228 38 non non JJ cord-277665-ac8txr3h 228 39 - - JJ cord-277665-ac8txr3h 228 40 complementary complementary JJ cord-277665-ac8txr3h 228 41 DNA dna NN cord-277665-ac8txr3h 228 42 oligonucleotides oligonucleotide NNS cord-277665-ac8txr3h 228 43 . . . cord-277665-ac8txr3h 229 1 The the DT cord-277665-ac8txr3h 229 2 electrolyte electrolyte NN cord-277665-ac8txr3h 229 3 - - HYPH cord-277665-ac8txr3h 229 4 solution solution NN cord-277665-ac8txr3h 229 5 - - HYPH cord-277665-ac8txr3h 229 6 gate gate NN cord-277665-ac8txr3h 229 7 field field NN cord-277665-ac8txr3h 229 8 - - HYPH cord-277665-ac8txr3h 229 9 effect effect NN cord-277665-ac8txr3h 229 10 transistors transistor NNS cord-277665-ac8txr3h 229 11 with with IN cord-277665-ac8txr3h 229 12 Hterminated Hterminated NNP cord-277665-ac8txr3h 229 13 polycrystalline polycrystalline NN cord-277665-ac8txr3h 229 14 diamond diamond NN cord-277665-ac8txr3h 229 15 surface surface NN cord-277665-ac8txr3h 229 16 were be VBD cord-277665-ac8txr3h 229 17 shown show VBN cord-277665-ac8txr3h 229 18 to to TO cord-277665-ac8txr3h 229 19 be be VB cord-277665-ac8txr3h 229 20 sensitive sensitive JJ cord-277665-ac8txr3h 229 21 to to IN cord-277665-ac8txr3h 229 22 Cl Cl NNP cord-277665-ac8txr3h 229 23 − − NNP cord-277665-ac8txr3h 229 24 and and CC cord-277665-ac8txr3h 229 25 Br Br NNP cord-277665-ac8txr3h 229 26 − − NNP cord-277665-ac8txr3h 229 27 and and CC cord-277665-ac8txr3h 229 28 can can MD cord-277665-ac8txr3h 229 29 find find VB cord-277665-ac8txr3h 229 30 application application NN cord-277665-ac8txr3h 229 31 in in IN cord-277665-ac8txr3h 229 32 cystic cystic JJ cord-277665-ac8txr3h 229 33 fibrosis fibrosis NN cord-277665-ac8txr3h 229 34 tests test NNS cord-277665-ac8txr3h 229 35 . . . cord-277665-ac8txr3h 230 1 The the DT cord-277665-ac8txr3h 230 2 capability capability NN cord-277665-ac8txr3h 230 3 for for IN cord-277665-ac8txr3h 230 4 biomolecular biomolecular JJ cord-277665-ac8txr3h 230 5 recognition recognition NN cord-277665-ac8txr3h 230 6 was be VBD cord-277665-ac8txr3h 230 7 provided provide VBN cord-277665-ac8txr3h 230 8 to to IN cord-277665-ac8txr3h 230 9 the the DT cord-277665-ac8txr3h 230 10 highly highly RB cord-277665-ac8txr3h 230 11 sensitive sensitive JJ cord-277665-ac8txr3h 230 12 field field NN cord-277665-ac8txr3h 230 13 - - HYPH cord-277665-ac8txr3h 230 14 effect effect NN cord-277665-ac8txr3h 230 15 transistor transistor NN cord-277665-ac8txr3h 230 16 ( ( -LRB- cord-277665-ac8txr3h 230 17 Bio Bio NNP cord-277665-ac8txr3h 230 18 - - HYPH cord-277665-ac8txr3h 230 19 FET FET NNP cord-277665-ac8txr3h 230 20 ) ) -RRB- cord-277665-ac8txr3h 230 21 made make VBD cord-277665-ac8txr3h 230 22 of of IN cord-277665-ac8txr3h 230 23 a a DT cord-277665-ac8txr3h 230 24 nanocrystalline nanocrystalline NNP cord-277665-ac8txr3h 230 25 diamond diamond NN cord-277665-ac8txr3h 230 26 thin thin JJ cord-277665-ac8txr3h 230 27 film film NN cord-277665-ac8txr3h 230 28 by by IN cord-277665-ac8txr3h 230 29 linking link VBG cord-277665-ac8txr3h 230 30 human human JJ cord-277665-ac8txr3h 230 31 immunoglobulin immunoglobulin NN cord-277665-ac8txr3h 230 32 G g NN cord-277665-ac8txr3h 230 33 to to IN cord-277665-ac8txr3h 230 34 the the DT cord-277665-ac8txr3h 230 35 diamond diamond NN cord-277665-ac8txr3h 230 36 surface surface NN cord-277665-ac8txr3h 230 37 . . . cord-277665-ac8txr3h 231 1 Electrical electrical JJ cord-277665-ac8txr3h 231 2 measurements measurement NNS cord-277665-ac8txr3h 231 3 showed show VBD cord-277665-ac8txr3h 231 4 that that IN cord-277665-ac8txr3h 231 5 the the DT cord-277665-ac8txr3h 231 6 Bio Bio NNP cord-277665-ac8txr3h 231 7 - - HYPH cord-277665-ac8txr3h 231 8 FET FET NNP cord-277665-ac8txr3h 231 9 responded respond VBD cord-277665-ac8txr3h 231 10 specifically specifically RB cord-277665-ac8txr3h 231 11 to to IN cord-277665-ac8txr3h 231 12 the the DT cord-277665-ac8txr3h 231 13 anti anti JJ cord-277665-ac8txr3h 231 14 - - JJ cord-277665-ac8txr3h 231 15 IgG igg JJ cord-277665-ac8txr3h 231 16 antibody antibody NN cord-277665-ac8txr3h 231 17 . . . cord-277665-ac8txr3h 232 1 Puzyr Puzyr NNP cord-277665-ac8txr3h 232 2 et et NNP cord-277665-ac8txr3h 232 3 al al NNP cord-277665-ac8txr3h 232 4 . . . cord-277665-ac8txr3h 233 1 ( ( -LRB- cord-277665-ac8txr3h 233 2 2004a 2004a CD cord-277665-ac8txr3h 233 3 ) ) -RRB- cord-277665-ac8txr3h 233 4 have have VBP cord-277665-ac8txr3h 233 5 recently recently RB cord-277665-ac8txr3h 233 6 developed develop VBN cord-277665-ac8txr3h 233 7 a a DT cord-277665-ac8txr3h 233 8 prototype prototype NN cord-277665-ac8txr3h 233 9 ND ND NNP cord-277665-ac8txr3h 233 10 - - HYPH cord-277665-ac8txr3h 233 11 based base VBN cord-277665-ac8txr3h 233 12 biochip biochip NN cord-277665-ac8txr3h 233 13 for for IN cord-277665-ac8txr3h 233 14 use use NN cord-277665-ac8txr3h 233 15 in in IN cord-277665-ac8txr3h 233 16 bioluminescent bioluminescent NN cord-277665-ac8txr3h 233 17 analysis analysis NN cord-277665-ac8txr3h 233 18 . . . cord-277665-ac8txr3h 234 1 The the DT cord-277665-ac8txr3h 234 2 biochip biochip NN cord-277665-ac8txr3h 234 3 incorporates incorporate VBZ cord-277665-ac8txr3h 234 4 aluminum aluminum NN cord-277665-ac8txr3h 234 5 oxide oxide NN cord-277665-ac8txr3h 234 6 film film NN cord-277665-ac8txr3h 234 7 - - HYPH cord-277665-ac8txr3h 234 8 adhesive adhesive NN cord-277665-ac8txr3h 234 9 layer layer NN cord-277665-ac8txr3h 234 10 - - HYPH cord-277665-ac8txr3h 234 11 deposited deposit VBN cord-277665-ac8txr3h 234 12 ND ND NNP cord-277665-ac8txr3h 234 13 particulate particulate NN cord-277665-ac8txr3h 234 14 - - HYPH cord-277665-ac8txr3h 234 15 luciferase luciferase NN cord-277665-ac8txr3h 234 16 , , , cord-277665-ac8txr3h 234 17 which which WDT cord-277665-ac8txr3h 234 18 retained retain VBD cord-277665-ac8txr3h 234 19 substantial substantial JJ cord-277665-ac8txr3h 234 20 enzymatic enzymatic JJ cord-277665-ac8txr3h 234 21 activity activity NN cord-277665-ac8txr3h 234 22 . . . cord-277665-ac8txr3h 235 1 It -PRON- PRP cord-277665-ac8txr3h 235 2 is be VBZ cord-277665-ac8txr3h 235 3 also also RB cord-277665-ac8txr3h 235 4 worth worth JJ cord-277665-ac8txr3h 235 5 mentioning mention VBG cord-277665-ac8txr3h 235 6 here here RB cord-277665-ac8txr3h 235 7 that that IN cord-277665-ac8txr3h 235 8 diamond diamond NN cord-277665-ac8txr3h 235 9 sensor sensor NN cord-277665-ac8txr3h 235 10 applications application NNS cord-277665-ac8txr3h 235 11 include include VBP cord-277665-ac8txr3h 235 12 high high JJ cord-277665-ac8txr3h 235 13 - - HYPH cord-277665-ac8txr3h 235 14 sensitivity sensitivity NN cord-277665-ac8txr3h 235 15 detection detection NN cord-277665-ac8txr3h 235 16 of of IN cord-277665-ac8txr3h 235 17 charged charge VBN cord-277665-ac8txr3h 235 18 particles particle NNS cord-277665-ac8txr3h 235 19 such such JJ cord-277665-ac8txr3h 235 20 as as IN cord-277665-ac8txr3h 235 21 protons proton NNS cord-277665-ac8txr3h 235 22 and and CC cord-277665-ac8txr3h 235 23 pions pion NNS cord-277665-ac8txr3h 235 24 that that WDT cord-277665-ac8txr3h 235 25 are be VBP cord-277665-ac8txr3h 235 26 possible possible JJ cord-277665-ac8txr3h 235 27 due due IN cord-277665-ac8txr3h 235 28 to to IN cord-277665-ac8txr3h 235 29 diamond diamond NN cord-277665-ac8txr3h 235 30 's 's POS cord-277665-ac8txr3h 235 31 high high JJ cord-277665-ac8txr3h 235 32 radiation radiation NN cord-277665-ac8txr3h 235 33 tolerance tolerance NN cord-277665-ac8txr3h 235 34 . . . cord-277665-ac8txr3h 236 1 A a DT cord-277665-ac8txr3h 236 2 CVD CVD NNP cord-277665-ac8txr3h 236 3 diamond diamond NN cord-277665-ac8txr3h 236 4 strip strip NN cord-277665-ac8txr3h 236 5 detector detector NN cord-277665-ac8txr3h 236 6 that that WDT cord-277665-ac8txr3h 236 7 can can MD cord-277665-ac8txr3h 236 8 be be VB cord-277665-ac8txr3h 236 9 used use VBN cord-277665-ac8txr3h 236 10 for for IN cord-277665-ac8txr3h 236 11 tracking tracking NN cord-277665-ac8txr3h 236 12 and and CC cord-277665-ac8txr3h 236 13 detection detection NN cord-277665-ac8txr3h 236 14 of of IN cord-277665-ac8txr3h 236 15 charged charge VBN cord-277665-ac8txr3h 236 16 particles particle NNS cord-277665-ac8txr3h 236 17 has have VBZ cord-277665-ac8txr3h 236 18 been be VBN cord-277665-ac8txr3h 236 19 recently recently RB cord-277665-ac8txr3h 236 20 introduced introduce VBN cord-277665-ac8txr3h 236 21 on on IN cord-277665-ac8txr3h 236 22 the the DT cord-277665-ac8txr3h 236 23 market market NN cord-277665-ac8txr3h 236 24 . . . cord-277665-ac8txr3h 237 1 Fast fast RB cord-277665-ac8txr3h 237 2 charged charge VBN cord-277665-ac8txr3h 237 3 particles particle NNS cord-277665-ac8txr3h 237 4 create create VBP cord-277665-ac8txr3h 237 5 charge charge NN cord-277665-ac8txr3h 237 6 carriers carrier NNS cord-277665-ac8txr3h 237 7 in in IN cord-277665-ac8txr3h 237 8 the the DT cord-277665-ac8txr3h 237 9 irradiated irradiate VBN cord-277665-ac8txr3h 237 10 diamond diamond NN cord-277665-ac8txr3h 237 11 followed follow VBN cord-277665-ac8txr3h 237 12 by by IN cord-277665-ac8txr3h 237 13 induction induction NN cord-277665-ac8txr3h 237 14 of of IN cord-277665-ac8txr3h 237 15 an an DT cord-277665-ac8txr3h 237 16 electric electric JJ cord-277665-ac8txr3h 237 17 charge charge NN cord-277665-ac8txr3h 237 18 on on IN cord-277665-ac8txr3h 237 19 the the DT cord-277665-ac8txr3h 237 20 strips strip NNS cord-277665-ac8txr3h 237 21 . . . cord-277665-ac8txr3h 238 1 Similarly similarly RB cord-277665-ac8txr3h 238 2 , , , cord-277665-ac8txr3h 238 3 detonation detonation NN cord-277665-ac8txr3h 238 4 ND ND NNP cord-277665-ac8txr3h 238 5 and and CC cord-277665-ac8txr3h 238 6 monocrystal monocrystal NNP cord-277665-ac8txr3h 238 7 CVD CVD NNP cord-277665-ac8txr3h 238 8 diamonds diamond NNS cord-277665-ac8txr3h 238 9 may may MD cord-277665-ac8txr3h 238 10 be be VB cord-277665-ac8txr3h 238 11 used use VBN cord-277665-ac8txr3h 238 12 for for IN cord-277665-ac8txr3h 238 13 detecting detect VBG cord-277665-ac8txr3h 238 14 both both DT cord-277665-ac8txr3h 238 15 intermediate intermediate JJ cord-277665-ac8txr3h 238 16 and and CC cord-277665-ac8txr3h 238 17 high high JJ cord-277665-ac8txr3h 238 18 - - HYPH cord-277665-ac8txr3h 238 19 energy energy NN cord-277665-ac8txr3h 238 20 heavy heavy JJ cord-277665-ac8txr3h 238 21 ions ion NNS cord-277665-ac8txr3h 238 22 and and CC cord-277665-ac8txr3h 238 23 in in IN cord-277665-ac8txr3h 238 24 other other JJ cord-277665-ac8txr3h 238 25 instrumental instrumental JJ cord-277665-ac8txr3h 238 26 analysis analysis NN cord-277665-ac8txr3h 238 27 ( ( -LRB- cord-277665-ac8txr3h 238 28 Adam Adam NNP cord-277665-ac8txr3h 238 29 et et NNP cord-277665-ac8txr3h 238 30 al al NNP cord-277665-ac8txr3h 238 31 . . NNP cord-277665-ac8txr3h 238 32 , , , cord-277665-ac8txr3h 238 33 2002 2002 CD cord-277665-ac8txr3h 238 34 ; ; : cord-277665-ac8txr3h 238 35 Berdermann Berdermann NNP cord-277665-ac8txr3h 238 36 et et FW cord-277665-ac8txr3h 238 37 al al NNP cord-277665-ac8txr3h 238 38 . . NNP cord-277665-ac8txr3h 238 39 , , , cord-277665-ac8txr3h 238 40 2004 2004 CD cord-277665-ac8txr3h 238 41 ) ) -RRB- cord-277665-ac8txr3h 238 42 . . . cord-277665-ac8txr3h 239 1 Because because IN cord-277665-ac8txr3h 239 2 both both DT cord-277665-ac8txr3h 239 3 carboxylated carboxylated JJ cord-277665-ac8txr3h 239 4 and and CC cord-277665-ac8txr3h 239 5 oxidized oxidize VBN cord-277665-ac8txr3h 239 6 ND ND NNP cord-277665-ac8txr3h 239 7 exhibit exhibit NN cord-277665-ac8txr3h 239 8 a a DT cord-277665-ac8txr3h 239 9 remarkably remarkably RB cord-277665-ac8txr3h 239 10 high high JJ cord-277665-ac8txr3h 239 11 affinity affinity NN cord-277665-ac8txr3h 239 12 for for IN cord-277665-ac8txr3h 239 13 proteins protein NNS cord-277665-ac8txr3h 239 14 , , , cord-277665-ac8txr3h 239 15 proteins protein NNS cord-277665-ac8txr3h 239 16 in in IN cord-277665-ac8txr3h 239 17 dilute dilute NN cord-277665-ac8txr3h 239 18 solutions solution NNS cord-277665-ac8txr3h 239 19 can can MD cord-277665-ac8txr3h 239 20 be be VB cord-277665-ac8txr3h 239 21 easily easily RB cord-277665-ac8txr3h 239 22 captured capture VBN cord-277665-ac8txr3h 239 23 by by IN cord-277665-ac8txr3h 239 24 NDs nd NNS cord-277665-ac8txr3h 239 25 with with IN cord-277665-ac8txr3h 239 26 a a DT cord-277665-ac8txr3h 239 27 size size NN cord-277665-ac8txr3h 239 28 of of IN cord-277665-ac8txr3h 239 29 100 100 CD cord-277665-ac8txr3h 239 30 nm nm NN cord-277665-ac8txr3h 239 31 , , , cord-277665-ac8txr3h 239 32 separated separate VBN cord-277665-ac8txr3h 239 33 by by IN cord-277665-ac8txr3h 239 34 centrifugation centrifugation NN cord-277665-ac8txr3h 239 35 , , , cord-277665-ac8txr3h 239 36 and and CC cord-277665-ac8txr3h 239 37 analyzed analyze VBN cord-277665-ac8txr3h 239 38 by by IN cord-277665-ac8txr3h 239 39 matrix matrix NN cord-277665-ac8txr3h 239 40 - - HYPH cord-277665-ac8txr3h 239 41 assisted assist VBN cord-277665-ac8txr3h 239 42 laser laser NN cord-277665-ac8txr3h 239 43 desorption desorption NN cord-277665-ac8txr3h 239 44 / / SYM cord-277665-ac8txr3h 239 45 ionization ionization NN cord-277665-ac8txr3h 239 46 time time NN cord-277665-ac8txr3h 239 47 - - HYPH cord-277665-ac8txr3h 239 48 of of IN cord-277665-ac8txr3h 239 49 - - HYPH cord-277665-ac8txr3h 239 50 flight flight NN cord-277665-ac8txr3h 239 51 mass mass NN cord-277665-ac8txr3h 239 52 spectrometry spectrometry NN cord-277665-ac8txr3h 239 53 ( ( -LRB- cord-277665-ac8txr3h 239 54 MALDI MALDI NNP cord-277665-ac8txr3h 239 55 - - HYPH cord-277665-ac8txr3h 239 56 TOF TOF NNP cord-277665-ac8txr3h 239 57 - - HYPH cord-277665-ac8txr3h 239 58 MS MS NNP cord-277665-ac8txr3h 239 59 ) ) -RRB- cord-277665-ac8txr3h 239 60 without without IN cord-277665-ac8txr3h 239 61 any any DT cord-277665-ac8txr3h 239 62 need need NN cord-277665-ac8txr3h 239 63 for for IN cord-277665-ac8txr3h 239 64 pre pre JJ cord-277665-ac8txr3h 239 65 - - NN cord-277665-ac8txr3h 239 66 separation separation NN cord-277665-ac8txr3h 239 67 of of IN cord-277665-ac8txr3h 239 68 the the DT cord-277665-ac8txr3h 239 69 adsorbed adsorb VBN cord-277665-ac8txr3h 239 70 proteins protein NNS cord-277665-ac8txr3h 239 71 from from IN cord-277665-ac8txr3h 239 72 ND ND NNP cord-277665-ac8txr3h 239 73 ( ( -LRB- cord-277665-ac8txr3h 239 74 Kong Kong NNP cord-277665-ac8txr3h 239 75 et et NNP cord-277665-ac8txr3h 239 76 al al NNP cord-277665-ac8txr3h 239 77 . . NNP cord-277665-ac8txr3h 239 78 , , , cord-277665-ac8txr3h 239 79 2005 2005 CD cord-277665-ac8txr3h 239 80 ) ) -RRB- cord-277665-ac8txr3h 239 81 . . . cord-277665-ac8txr3h 240 1 With with IN cord-277665-ac8txr3h 240 2 the the DT cord-277665-ac8txr3h 240 3 dilute dilute JJ cord-277665-ac8txr3h 240 4 mixed mixed JJ cord-277665-ac8txr3h 240 5 solution solution NN cord-277665-ac8txr3h 240 6 of of IN cord-277665-ac8txr3h 240 7 cytochrome cytochrome NN cord-277665-ac8txr3h 240 8 c c NN cord-277665-ac8txr3h 240 9 , , , cord-277665-ac8txr3h 240 10 myoglobin myoglobin NN cord-277665-ac8txr3h 240 11 , , , cord-277665-ac8txr3h 240 12 and and CC cord-277665-ac8txr3h 240 13 albumin albumin NN cord-277665-ac8txr3h 240 14 that that WDT cord-277665-ac8txr3h 240 15 preferentially preferentially RB cord-277665-ac8txr3h 240 16 adsorbs adsorb VBZ cord-277665-ac8txr3h 240 17 on on IN cord-277665-ac8txr3h 240 18 a a DT cord-277665-ac8txr3h 240 19 hydrophilic hydrophilic JJ cord-277665-ac8txr3h 240 20 surface surface NN cord-277665-ac8txr3h 240 21 , , , cord-277665-ac8txr3h 240 22 the the DT cord-277665-ac8txr3h 240 23 developed develop VBN cord-277665-ac8txr3h 240 24 method method NN cord-277665-ac8txr3h 240 25 offered offer VBD cord-277665-ac8txr3h 240 26 significantly significantly RB cord-277665-ac8txr3h 240 27 higher high JJR cord-277665-ac8txr3h 240 28 sensitivity sensitivity NN cord-277665-ac8txr3h 240 29 than than IN cord-277665-ac8txr3h 240 30 conventional conventional JJ cord-277665-ac8txr3h 240 31 MALDI MALDI NNS cord-277665-ac8txr3h 240 32 - - HYPH cord-277665-ac8txr3h 240 33 TOF TOF NNP cord-277665-ac8txr3h 240 34 - - HYPH cord-277665-ac8txr3h 240 35 MS MS NNP cord-277665-ac8txr3h 240 36 and and CC cord-277665-ac8txr3h 240 37 had have VBD cord-277665-ac8txr3h 240 38 a a DT cord-277665-ac8txr3h 240 39 limit limit NN cord-277665-ac8txr3h 240 40 of of IN cord-277665-ac8txr3h 240 41 detection detection NN cord-277665-ac8txr3h 240 42 of of IN cord-277665-ac8txr3h 240 43 100 100 CD cord-277665-ac8txr3h 240 44 pM pm NN cord-277665-ac8txr3h 240 45 for for IN cord-277665-ac8txr3h 240 46 a a DT cord-277665-ac8txr3h 240 47 1 1 CD cord-277665-ac8txr3h 240 48 mL ml NN cord-277665-ac8txr3h 240 49 sample sample NN cord-277665-ac8txr3h 240 50 solution solution NN cord-277665-ac8txr3h 240 51 . . . cord-277665-ac8txr3h 241 1 The the DT cord-277665-ac8txr3h 241 2 potential potential NN cord-277665-ac8txr3h 241 3 of of IN cord-277665-ac8txr3h 241 4 ND ND NNP cord-277665-ac8txr3h 241 5 - - HYPH cord-277665-ac8txr3h 241 6 assisted assist VBN cord-277665-ac8txr3h 241 7 MALDI MALDI NNP cord-277665-ac8txr3h 241 8 - - HYPH cord-277665-ac8txr3h 241 9 TOF TOF NNP cord-277665-ac8txr3h 241 10 - - HYPH cord-277665-ac8txr3h 241 11 MS MS NNP cord-277665-ac8txr3h 241 12 for for IN cord-277665-ac8txr3h 241 13 use use NN cord-277665-ac8txr3h 241 14 in in IN cord-277665-ac8txr3h 241 15 clinical clinical JJ cord-277665-ac8txr3h 241 16 proteomics proteomic NNS cord-277665-ac8txr3h 241 17 was be VBD cord-277665-ac8txr3h 241 18 demonstrated demonstrate VBN cord-277665-ac8txr3h 241 19 with with IN cord-277665-ac8txr3h 241 20 human human JJ cord-277665-ac8txr3h 241 21 blood blood NN cord-277665-ac8txr3h 241 22 serum serum NN cord-277665-ac8txr3h 241 23 analysis analysis NN cord-277665-ac8txr3h 242 1 ( ( -LRB- cord-277665-ac8txr3h 242 2 Kong Kong NNP cord-277665-ac8txr3h 242 3 et et NNP cord-277665-ac8txr3h 242 4 al al NNP cord-277665-ac8txr3h 242 5 . . NNP cord-277665-ac8txr3h 242 6 , , , cord-277665-ac8txr3h 242 7 2005 2005 CD cord-277665-ac8txr3h 242 8 ) ) -RRB- cord-277665-ac8txr3h 242 9 . . . cord-277665-ac8txr3h 243 1 If if IN cord-277665-ac8txr3h 243 2 necessary necessary JJ cord-277665-ac8txr3h 243 3 , , , cord-277665-ac8txr3h 243 4 surfaces surface NNS cord-277665-ac8txr3h 243 5 of of IN cord-277665-ac8txr3h 243 6 ND ND NNP cord-277665-ac8txr3h 243 7 particles particle NNS cord-277665-ac8txr3h 243 8 can can MD cord-277665-ac8txr3h 243 9 be be VB cord-277665-ac8txr3h 243 10 modified modify VBN cord-277665-ac8txr3h 243 11 to to TO cord-277665-ac8txr3h 243 12 decrease decrease VB cord-277665-ac8txr3h 243 13 non non JJ cord-277665-ac8txr3h 243 14 - - JJ cord-277665-ac8txr3h 243 15 specific specific JJ cord-277665-ac8txr3h 243 16 protein protein NN cord-277665-ac8txr3h 243 17 adsorption adsorption NN cord-277665-ac8txr3h 243 18 and and CC cord-277665-ac8txr3h 243 19 optimize optimize VB cord-277665-ac8txr3h 243 20 their -PRON- PRP$ cord-277665-ac8txr3h 243 21 use use NN cord-277665-ac8txr3h 243 22 for for IN cord-277665-ac8txr3h 243 23 bioanalysis bioanalysis NN cord-277665-ac8txr3h 243 24 ( ( -LRB- cord-277665-ac8txr3h 243 25 Lasseter Lasseter NNP cord-277665-ac8txr3h 243 26 et et NNP cord-277665-ac8txr3h 243 27 al al NNP cord-277665-ac8txr3h 243 28 . . NNP cord-277665-ac8txr3h 243 29 , , , cord-277665-ac8txr3h 243 30 2004 2004 CD cord-277665-ac8txr3h 243 31 ) ) -RRB- cord-277665-ac8txr3h 243 32 . . . cord-277665-ac8txr3h 244 1 Application application NN cord-277665-ac8txr3h 244 2 of of IN cord-277665-ac8txr3h 244 3 detonation detonation NN cord-277665-ac8txr3h 244 4 NDs nd NNS cord-277665-ac8txr3h 244 5 facilitated facilitate VBN cord-277665-ac8txr3h 244 6 separation separation NN cord-277665-ac8txr3h 244 7 of of IN cord-277665-ac8txr3h 244 8 Obelia Obelia NNP cord-277665-ac8txr3h 244 9 longissima longissima NN cord-277665-ac8txr3h 244 10 apoobelin apoobelin NN cord-277665-ac8txr3h 244 11 from from IN cord-277665-ac8txr3h 244 12 the the DT cord-277665-ac8txr3h 244 13 recombinant recombinant JJ cord-277665-ac8txr3h 244 14 E. E. NNP cord-277665-ac8txr3h 244 15 coli coli VBZ cord-277665-ac8txr3h 244 16 cell cell NN cord-277665-ac8txr3h 244 17 extract extract NN cord-277665-ac8txr3h 244 18 and and CC cord-277665-ac8txr3h 244 19 made make VBD cord-277665-ac8txr3h 244 20 possible possible JJ cord-277665-ac8txr3h 244 21 the the DT cord-277665-ac8txr3h 244 22 preparation preparation NN cord-277665-ac8txr3h 244 23 of of IN cord-277665-ac8txr3h 244 24 purified purify VBN cord-277665-ac8txr3h 244 25 protein protein NN cord-277665-ac8txr3h 244 26 with with IN cord-277665-ac8txr3h 244 27 a a DT cord-277665-ac8txr3h 244 28 yield yield NN cord-277665-ac8txr3h 244 29 of of IN cord-277665-ac8txr3h 244 30 up up IN cord-277665-ac8txr3h 244 31 to to TO cord-277665-ac8txr3h 244 32 38 38 CD cord-277665-ac8txr3h 244 33 % % NN cord-277665-ac8txr3h 244 34 . . . cord-277665-ac8txr3h 245 1 Within within IN cord-277665-ac8txr3h 245 2 the the DT cord-277665-ac8txr3h 245 3 ND ND NNP cord-277665-ac8txr3h 245 4 family family NN cord-277665-ac8txr3h 245 5 , , , cord-277665-ac8txr3h 245 6 to to IN cord-277665-ac8txr3h 245 7 a a DT cord-277665-ac8txr3h 245 8 large large JJ cord-277665-ac8txr3h 245 9 extent extent NN cord-277665-ac8txr3h 245 10 medical medical JJ cord-277665-ac8txr3h 245 11 applications application NNS cord-277665-ac8txr3h 245 12 have have VBP cord-277665-ac8txr3h 245 13 been be VBN cord-277665-ac8txr3h 245 14 developed develop VBN cord-277665-ac8txr3h 245 15 for for IN cord-277665-ac8txr3h 245 16 diamondoids diamondoid NNS cord-277665-ac8txr3h 245 17 . . . cord-277665-ac8txr3h 246 1 Diamondoids Diamondoids NNP cord-277665-ac8txr3h 246 2 such such JJ cord-277665-ac8txr3h 246 3 as as IN cord-277665-ac8txr3h 246 4 adamantane adamantane NNP cord-277665-ac8txr3h 246 5 derivatives derivative NNS cord-277665-ac8txr3h 246 6 ( ( -LRB- cord-277665-ac8txr3h 246 7 single single JJ cord-277665-ac8txr3h 246 8 - - HYPH cord-277665-ac8txr3h 246 9 molecule molecule NN cord-277665-ac8txr3h 246 10 unit unit NN cord-277665-ac8txr3h 246 11 of of IN cord-277665-ac8txr3h 246 12 diamond diamond NN cord-277665-ac8txr3h 246 13 with with IN cord-277665-ac8txr3h 246 14 the the DT cord-277665-ac8txr3h 246 15 formula formula NN cord-277665-ac8txr3h 246 16 C c NN cord-277665-ac8txr3h 246 17 10 10 CD cord-277665-ac8txr3h 246 18 H H NNP cord-277665-ac8txr3h 246 19 16 16 CD cord-277665-ac8txr3h 246 20 ) ) -RRB- cord-277665-ac8txr3h 246 21 have have VBP cord-277665-ac8txr3h 246 22 been be VBN cord-277665-ac8txr3h 246 23 used use VBN cord-277665-ac8txr3h 246 24 in in IN cord-277665-ac8txr3h 246 25 pharmacology pharmacology NN cord-277665-ac8txr3h 246 26 , , , cord-277665-ac8txr3h 246 27 clinical clinical JJ cord-277665-ac8txr3h 246 28 medicine medicine NN cord-277665-ac8txr3h 246 29 , , , cord-277665-ac8txr3h 246 30 and and CC cord-277665-ac8txr3h 246 31 biosensing biosense VBG cord-277665-ac8txr3h 246 32 ( ( -LRB- cord-277665-ac8txr3h 246 33 Freitas Freitas NNP cord-277665-ac8txr3h 246 34 , , , cord-277665-ac8txr3h 246 35 2003 2003 CD cord-277665-ac8txr3h 246 36 ) ) -RRB- cord-277665-ac8txr3h 246 37 . . . cord-277665-ac8txr3h 247 1 Until until IN cord-277665-ac8txr3h 247 2 recently recently RB cord-277665-ac8txr3h 247 3 the the DT cord-277665-ac8txr3h 247 4 cholinesterase cholinesterase NN cord-277665-ac8txr3h 247 5 inhibitors inhibitor NNS cord-277665-ac8txr3h 247 6 were be VBD cord-277665-ac8txr3h 247 7 the the DT cord-277665-ac8txr3h 247 8 only only JJ cord-277665-ac8txr3h 247 9 available available JJ cord-277665-ac8txr3h 247 10 drugs drug NNS cord-277665-ac8txr3h 247 11 for for IN cord-277665-ac8txr3h 247 12 the the DT cord-277665-ac8txr3h 247 13 treatment treatment NN cord-277665-ac8txr3h 247 14 of of IN cord-277665-ac8txr3h 247 15 Alzheimer Alzheimer NNP cord-277665-ac8txr3h 247 16 's 's POS cord-277665-ac8txr3h 247 17 disease disease NN cord-277665-ac8txr3h 247 18 , , , cord-277665-ac8txr3h 247 19 which which WDT cord-277665-ac8txr3h 247 20 is be VBZ cord-277665-ac8txr3h 247 21 one one CD cord-277665-ac8txr3h 247 22 of of IN cord-277665-ac8txr3h 247 23 the the DT cord-277665-ac8txr3h 247 24 leading lead VBG cord-277665-ac8txr3h 247 25 causes cause NNS cord-277665-ac8txr3h 247 26 of of IN cord-277665-ac8txr3h 247 27 death death NN cord-277665-ac8txr3h 247 28 for for IN cord-277665-ac8txr3h 247 29 people people NNS cord-277665-ac8txr3h 247 30 over over IN cord-277665-ac8txr3h 247 31 65 65 CD cord-277665-ac8txr3h 247 32 years year NNS cord-277665-ac8txr3h 247 33 of of IN cord-277665-ac8txr3h 247 34 age age NN cord-277665-ac8txr3h 247 35 . . . cord-277665-ac8txr3h 248 1 Unfortunately unfortunately RB cord-277665-ac8txr3h 248 2 , , , cord-277665-ac8txr3h 248 3 the the DT cord-277665-ac8txr3h 248 4 cholinesterase cholinesterase NN cord-277665-ac8txr3h 248 5 inhibitors inhibitor NNS cord-277665-ac8txr3h 248 6 can can MD cord-277665-ac8txr3h 248 7 not not RB cord-277665-ac8txr3h 248 8 stop stop VB cord-277665-ac8txr3h 248 9 the the DT cord-277665-ac8txr3h 248 10 process process NN cord-277665-ac8txr3h 248 11 of of IN cord-277665-ac8txr3h 248 12 neurodegeneration neurodegeneration NN cord-277665-ac8txr3h 248 13 and and CC cord-277665-ac8txr3h 248 14 just just RB cord-277665-ac8txr3h 248 15 symptomatically symptomatically RB cord-277665-ac8txr3h 248 16 enhance enhance VB cord-277665-ac8txr3h 248 17 the the DT cord-277665-ac8txr3h 248 18 cognitive cognitive JJ cord-277665-ac8txr3h 248 19 state state NN cord-277665-ac8txr3h 248 20 to to IN cord-277665-ac8txr3h 248 21 some some DT cord-277665-ac8txr3h 248 22 degree degree NN cord-277665-ac8txr3h 248 23 ( ( -LRB- cord-277665-ac8txr3h 248 24 Sonkusare Sonkusare NNP cord-277665-ac8txr3h 248 25 et et NNP cord-277665-ac8txr3h 248 26 al al NNP cord-277665-ac8txr3h 248 27 . . NNP cord-277665-ac8txr3h 248 28 , , , cord-277665-ac8txr3h 248 29 2005 2005 CD cord-277665-ac8txr3h 248 30 ) ) -RRB- cord-277665-ac8txr3h 248 31 . . . cord-277665-ac8txr3h 249 1 In in IN cord-277665-ac8txr3h 249 2 Alzheimer Alzheimer NNP cord-277665-ac8txr3h 249 3 's 's POS cord-277665-ac8txr3h 249 4 disease disease NN cord-277665-ac8txr3h 249 5 , , , cord-277665-ac8txr3h 249 6 neuronal neuronal JJ cord-277665-ac8txr3h 249 7 death death NN cord-277665-ac8txr3h 249 8 is be VBZ cord-277665-ac8txr3h 249 9 caused cause VBN cord-277665-ac8txr3h 249 10 by by IN cord-277665-ac8txr3h 249 11 glutamate glutamate NN cord-277665-ac8txr3h 249 12 excitotoxicity excitotoxicity NN cord-277665-ac8txr3h 249 13 mediated mediate VBN cord-277665-ac8txr3h 249 14 through through IN cord-277665-ac8txr3h 249 15 the the DT cord-277665-ac8txr3h 249 16 N n NN cord-277665-ac8txr3h 249 17 - - HYPH cord-277665-ac8txr3h 249 18 methyl methyl NN cord-277665-ac8txr3h 249 19 - - HYPH cord-277665-ac8txr3h 249 20 D d NN cord-277665-ac8txr3h 249 21 - - HYPH cord-277665-ac8txr3h 249 22 aspartate aspartate NN cord-277665-ac8txr3h 249 23 ( ( -LRB- cord-277665-ac8txr3h 249 24 NMDA NMDA NNP cord-277665-ac8txr3h 249 25 ) ) -RRB- cord-277665-ac8txr3h 249 26 receptors receptor NNS cord-277665-ac8txr3h 249 27 making make VBG cord-277665-ac8txr3h 249 28 them -PRON- PRP cord-277665-ac8txr3h 249 29 an an DT cord-277665-ac8txr3h 249 30 excellent excellent JJ cord-277665-ac8txr3h 249 31 target target NN cord-277665-ac8txr3h 249 32 for for IN cord-277665-ac8txr3h 249 33 preventing prevent VBG cord-277665-ac8txr3h 249 34 the the DT cord-277665-ac8txr3h 249 35 disease disease NN cord-277665-ac8txr3h 249 36 . . . cord-277665-ac8txr3h 250 1 Excitotoxicity excitotoxicity NN cord-277665-ac8txr3h 250 2 is be VBZ cord-277665-ac8txr3h 250 3 excessive excessive JJ cord-277665-ac8txr3h 250 4 exposure exposure NN cord-277665-ac8txr3h 250 5 to to IN cord-277665-ac8txr3h 250 6 the the DT cord-277665-ac8txr3h 250 7 neurotransmitter neurotransmitter NN cord-277665-ac8txr3h 250 8 glutamate glutamate NN cord-277665-ac8txr3h 250 9 or or CC cord-277665-ac8txr3h 250 10 overstimulation overstimulation NN cord-277665-ac8txr3h 250 11 of of IN cord-277665-ac8txr3h 250 12 its -PRON- PRP$ cord-277665-ac8txr3h 250 13 membrane membrane NN cord-277665-ac8txr3h 250 14 receptors receptor NNS cord-277665-ac8txr3h 250 15 , , , cord-277665-ac8txr3h 250 16 leading lead VBG cord-277665-ac8txr3h 250 17 to to IN cord-277665-ac8txr3h 250 18 neuronal neuronal JJ cord-277665-ac8txr3h 250 19 injury injury NN cord-277665-ac8txr3h 250 20 or or CC cord-277665-ac8txr3h 250 21 death death NN cord-277665-ac8txr3h 250 22 . . . cord-277665-ac8txr3h 251 1 Activity activity NN cord-277665-ac8txr3h 251 2 of of IN cord-277665-ac8txr3h 251 3 the the DT cord-277665-ac8txr3h 251 4 nmDA nmda JJ cord-277665-ac8txr3h 251 5 receptor receptor NN cord-277665-ac8txr3h 251 6 is be VBZ cord-277665-ac8txr3h 251 7 also also RB cord-277665-ac8txr3h 251 8 essential essential JJ cord-277665-ac8txr3h 251 9 for for IN cord-277665-ac8txr3h 251 10 normal normal JJ cord-277665-ac8txr3h 251 11 neuronal neuronal JJ cord-277665-ac8txr3h 251 12 function function NN cord-277665-ac8txr3h 251 13 , , , cord-277665-ac8txr3h 251 14 and and CC cord-277665-ac8txr3h 251 15 neuroprotective neuroprotective JJ cord-277665-ac8txr3h 251 16 agents agent NNS cord-277665-ac8txr3h 251 17 that that WDT cord-277665-ac8txr3h 251 18 fully fully RB cord-277665-ac8txr3h 251 19 block block VBP cord-277665-ac8txr3h 251 20 nmDA nmda JJ cord-277665-ac8txr3h 251 21 receptor receptor NN cord-277665-ac8txr3h 251 22 activity activity NN cord-277665-ac8txr3h 251 23 will will MD cord-277665-ac8txr3h 251 24 have have VB cord-277665-ac8txr3h 251 25 severe severe JJ cord-277665-ac8txr3h 251 26 side side NN cord-277665-ac8txr3h 251 27 effects effect NNS cord-277665-ac8txr3h 251 28 ( ( -LRB- cord-277665-ac8txr3h 251 29 Lipton Lipton NNP cord-277665-ac8txr3h 251 30 , , , cord-277665-ac8txr3h 251 31 2004 2004 CD cord-277665-ac8txr3h 251 32 ) ) -RRB- cord-277665-ac8txr3h 251 33 . . . cord-277665-ac8txr3h 252 1 Memantine Memantine NNP cord-277665-ac8txr3h 252 2 ( ( -LRB- cord-277665-ac8txr3h 252 3 1-amino 1-amino CD cord-277665-ac8txr3h 252 4 adamantane adamantane NNP cord-277665-ac8txr3h 252 5 derivative derivative NNP cord-277665-ac8txr3h 252 6 ) ) -RRB- cord-277665-ac8txr3h 252 7 is be VBZ cord-277665-ac8txr3h 252 8 the the DT cord-277665-ac8txr3h 252 9 potent potent JJ cord-277665-ac8txr3h 252 10 nmDA nmda JJ cord-277665-ac8txr3h 252 11 - - HYPH cord-277665-ac8txr3h 252 12 receptor receptor NN cord-277665-ac8txr3h 252 13 antagonist antagonist NN cord-277665-ac8txr3h 252 14 that that WDT cord-277665-ac8txr3h 252 15 blocks block VBZ cord-277665-ac8txr3h 252 16 excessive excessive JJ cord-277665-ac8txr3h 252 17 NMDA NMDA NNP cord-277665-ac8txr3h 252 18 receptor receptor NN cord-277665-ac8txr3h 252 19 activity activity NN cord-277665-ac8txr3h 252 20 without without IN cord-277665-ac8txr3h 252 21 disrupting disrupt VBG cord-277665-ac8txr3h 252 22 normal normal JJ cord-277665-ac8txr3h 252 23 activity activity NN cord-277665-ac8txr3h 252 24 through through IN cord-277665-ac8txr3h 252 25 its -PRON- PRP$ cord-277665-ac8txr3h 252 26 action action NN cord-277665-ac8txr3h 252 27 as as IN cord-277665-ac8txr3h 252 28 an an DT cord-277665-ac8txr3h 252 29 uncompetitive uncompetitive JJ cord-277665-ac8txr3h 252 30 , , , cord-277665-ac8txr3h 252 31 low low JJ cord-277665-ac8txr3h 252 32 - - HYPH cord-277665-ac8txr3h 252 33 affinity affinity NN cord-277665-ac8txr3h 252 34 , , , cord-277665-ac8txr3h 252 35 open open JJ cord-277665-ac8txr3h 252 36 - - HYPH cord-277665-ac8txr3h 252 37 channel channel NN cord-277665-ac8txr3h 252 38 blocker blocker NN cord-277665-ac8txr3h 252 39 . . . cord-277665-ac8txr3h 253 1 It -PRON- PRP cord-277665-ac8txr3h 253 2 also also RB cord-277665-ac8txr3h 253 3 has have VBZ cord-277665-ac8txr3h 253 4 beneficial beneficial JJ cord-277665-ac8txr3h 253 5 effects effect NNS cord-277665-ac8txr3h 253 6 in in IN cord-277665-ac8txr3h 253 7 Parkinson Parkinson NNP cord-277665-ac8txr3h 253 8 's 's POS cord-277665-ac8txr3h 253 9 disease disease NN cord-277665-ac8txr3h 253 10 , , , cord-277665-ac8txr3h 253 11 stroke stroke NN cord-277665-ac8txr3h 253 12 , , , cord-277665-ac8txr3h 253 13 epilepsy epilepsy NN cord-277665-ac8txr3h 253 14 , , , cord-277665-ac8txr3h 253 15 central central JJ cord-277665-ac8txr3h 253 16 nervous nervous JJ cord-277665-ac8txr3h 253 17 system system NN cord-277665-ac8txr3h 253 18 ( ( -LRB- cord-277665-ac8txr3h 253 19 CNS CNS NNP cord-277665-ac8txr3h 253 20 ) ) -RRB- cord-277665-ac8txr3h 253 21 trauma trauma NN cord-277665-ac8txr3h 253 22 , , , cord-277665-ac8txr3h 253 23 amyotrophic amyotrophic JJ cord-277665-ac8txr3h 253 24 lateral lateral JJ cord-277665-ac8txr3h 253 25 sclerosis sclerosis NN cord-277665-ac8txr3h 253 26 , , , cord-277665-ac8txr3h 253 27 drug drug NN cord-277665-ac8txr3h 253 28 dependence dependence NN cord-277665-ac8txr3h 253 29 , , , cord-277665-ac8txr3h 253 30 chronic chronic JJ cord-277665-ac8txr3h 253 31 pain pain NN cord-277665-ac8txr3h 253 32 , , , cord-277665-ac8txr3h 253 33 depression depression NN cord-277665-ac8txr3h 253 34 , , , cord-277665-ac8txr3h 253 35 glaucoma glaucoma NN cord-277665-ac8txr3h 253 36 , , , cord-277665-ac8txr3h 253 37 and and CC cord-277665-ac8txr3h 253 38 severe severe JJ cord-277665-ac8txr3h 253 39 neuropathic neuropathic JJ cord-277665-ac8txr3h 253 40 pain pain NN cord-277665-ac8txr3h 253 41 . . . cord-277665-ac8txr3h 254 1 Memantine Memantine NNP cord-277665-ac8txr3h 254 2 is be VBZ cord-277665-ac8txr3h 254 3 available available JJ cord-277665-ac8txr3h 254 4 in in IN cord-277665-ac8txr3h 254 5 Europe Europe NNP cord-277665-ac8txr3h 254 6 and and CC cord-277665-ac8txr3h 254 7 has have VBZ cord-277665-ac8txr3h 254 8 been be VBN cord-277665-ac8txr3h 254 9 recently recently RB cord-277665-ac8txr3h 254 10 approved approve VBN cord-277665-ac8txr3h 254 11 for for IN cord-277665-ac8txr3h 254 12 treatment treatment NN cord-277665-ac8txr3h 254 13 of of IN cord-277665-ac8txr3h 254 14 dementia dementia NN cord-277665-ac8txr3h 254 15 in in IN cord-277665-ac8txr3h 254 16 the the DT cord-277665-ac8txr3h 254 17 USA USA NNP cord-277665-ac8txr3h 254 18 . . . cord-277665-ac8txr3h 255 1 At at IN cord-277665-ac8txr3h 255 2 the the DT cord-277665-ac8txr3h 255 3 present present JJ cord-277665-ac8txr3h 255 4 time time NN cord-277665-ac8txr3h 255 5 the the DT cord-277665-ac8txr3h 255 6 second second JJ cord-277665-ac8txr3h 255 7 - - HYPH cord-277665-ac8txr3h 255 8 generation generation NN cord-277665-ac8txr3h 255 9 memantine memantine NNP cord-277665-ac8txr3h 255 10 derivatives derivative NNS cord-277665-ac8txr3h 255 11 , , , cord-277665-ac8txr3h 255 12 which which WDT cord-277665-ac8txr3h 255 13 take take VBP cord-277665-ac8txr3h 255 14 advantage advantage NN cord-277665-ac8txr3h 255 15 of of IN cord-277665-ac8txr3h 255 16 the the DT cord-277665-ac8txr3h 255 17 additional additional JJ cord-277665-ac8txr3h 255 18 modulatory modulatory JJ cord-277665-ac8txr3h 255 19 sites site NNS cord-277665-ac8txr3h 255 20 in in IN cord-277665-ac8txr3h 255 21 the the DT cord-277665-ac8txr3h 255 22 NMDA NMDA NNP cord-277665-ac8txr3h 255 23 receptor receptor NN cord-277665-ac8txr3h 255 24 that that WDT cord-277665-ac8txr3h 255 25 could could MD cord-277665-ac8txr3h 255 26 also also RB cord-277665-ac8txr3h 255 27 be be VB cord-277665-ac8txr3h 255 28 used use VBN cord-277665-ac8txr3h 255 29 for for IN cord-277665-ac8txr3h 255 30 clinical clinical JJ cord-277665-ac8txr3h 255 31 intervention intervention NN cord-277665-ac8txr3h 255 32 , , , cord-277665-ac8txr3h 255 33 are be VBP cord-277665-ac8txr3h 255 34 under under IN cord-277665-ac8txr3h 255 35 development development NN cord-277665-ac8txr3h 255 36 ( ( -LRB- cord-277665-ac8txr3h 255 37 Lipton Lipton NNP cord-277665-ac8txr3h 255 38 , , , cord-277665-ac8txr3h 255 39 2004 2004 CD cord-277665-ac8txr3h 255 40 ; ; : cord-277665-ac8txr3h 255 41 Sonkusare Sonkusare NNP cord-277665-ac8txr3h 255 42 et et NNP cord-277665-ac8txr3h 255 43 al al NNP cord-277665-ac8txr3h 255 44 . . NNP cord-277665-ac8txr3h 255 45 , , , cord-277665-ac8txr3h 255 46 2005 2005 CD cord-277665-ac8txr3h 255 47 ) ) -RRB- cord-277665-ac8txr3h 255 48 . . . cord-277665-ac8txr3h 256 1 Many many JJ cord-277665-ac8txr3h 256 2 adamantane adamantane NN cord-277665-ac8txr3h 256 3 derivatives derivative NNS cord-277665-ac8txr3h 256 4 possess possess VBP cord-277665-ac8txr3h 256 5 antibacterial antibacterial JJ cord-277665-ac8txr3h 256 6 , , , cord-277665-ac8txr3h 256 7 antiviral antiviral JJ cord-277665-ac8txr3h 256 8 , , , cord-277665-ac8txr3h 256 9 and and CC cord-277665-ac8txr3h 256 10 antifungal antifungal JJ cord-277665-ac8txr3h 256 11 activity activity NN cord-277665-ac8txr3h 256 12 ( ( -LRB- cord-277665-ac8txr3h 256 13 Wang Wang NNP cord-277665-ac8txr3h 256 14 et et NNP cord-277665-ac8txr3h 256 15 al al NNP cord-277665-ac8txr3h 256 16 . . NNP cord-277665-ac8txr3h 256 17 , , , cord-277665-ac8txr3h 256 18 1998 1998 CD cord-277665-ac8txr3h 256 19 ; ; : cord-277665-ac8txr3h 256 20 El El NNP cord-277665-ac8txr3h 256 21 - - HYPH cord-277665-ac8txr3h 256 22 Sherbeny Sherbeny NNP cord-277665-ac8txr3h 256 23 , , , cord-277665-ac8txr3h 256 24 2000 2000 CD cord-277665-ac8txr3h 256 25 ; ; : cord-277665-ac8txr3h 257 1 Orzeszko Orzeszko NNP cord-277665-ac8txr3h 257 2 et et NNP cord-277665-ac8txr3h 257 3 al al NNP cord-277665-ac8txr3h 257 4 . . NNP cord-277665-ac8txr3h 257 5 , , , cord-277665-ac8txr3h 257 6 2002 2002 CD cord-277665-ac8txr3h 257 7 ; ; : cord-277665-ac8txr3h 257 8 El El NNP cord-277665-ac8txr3h 257 9 - - HYPH cord-277665-ac8txr3h 257 10 Emam Emam NNP cord-277665-ac8txr3h 257 11 et et NNP cord-277665-ac8txr3h 257 12 al al NNP cord-277665-ac8txr3h 257 13 . . NNP cord-277665-ac8txr3h 257 14 , , , cord-277665-ac8txr3h 257 15 2004 2004 CD cord-277665-ac8txr3h 257 16 ) ) -RRB- cord-277665-ac8txr3h 257 17 . . . cord-277665-ac8txr3h 258 1 For for IN cord-277665-ac8txr3h 258 2 example example NN cord-277665-ac8txr3h 258 3 , , , cord-277665-ac8txr3h 258 4 5-(Iadamantyl)-2-substituted 5-(iadamantyl)-2-substituted CD cord-277665-ac8txr3h 258 5 thio-1,3,4-oxadiazoles thio-1,3,4-oxadiazole NNS cord-277665-ac8txr3h 258 6 and and CC cord-277665-ac8txr3h 258 7 5-(1-adamantyl)-3substituted 5-(1-adamantyl)-3substituted CD cord-277665-ac8txr3h 258 8 aminomethyl-1,3,4-oxadiazoline-2-thiones aminomethyl-1,3,4-oxadiazoline-2-thione NNS cord-277665-ac8txr3h 258 9 exhibit exhibit VBP cord-277665-ac8txr3h 258 10 substantial substantial JJ cord-277665-ac8txr3h 258 11 antimicrobial antimicrobial JJ cord-277665-ac8txr3h 258 12 activity activity NN cord-277665-ac8txr3h 258 13 against against IN cord-277665-ac8txr3h 258 14 Gram gram NN cord-277665-ac8txr3h 258 15 - - HYPH cord-277665-ac8txr3h 258 16 positive positive JJ cord-277665-ac8txr3h 258 17 bacteria bacteria NNS cord-277665-ac8txr3h 258 18 and and CC cord-277665-ac8txr3h 258 19 the the DT cord-277665-ac8txr3h 258 20 antiviral antiviral JJ cord-277665-ac8txr3h 258 21 activity activity NN cord-277665-ac8txr3h 258 22 against against IN cord-277665-ac8txr3h 258 23 HIV-1 HIV-1 NNP cord-277665-ac8txr3h 258 24 significantly significantly RB cord-277665-ac8txr3h 258 25 reducing reduce VBG cord-277665-ac8txr3h 258 26 viral viral JJ cord-277665-ac8txr3h 258 27 replication replication NN cord-277665-ac8txr3h 258 28 at at IN cord-277665-ac8txr3h 258 29 2 2 CD cord-277665-ac8txr3h 258 30 - - SYM cord-277665-ac8txr3h 258 31 50 50 CD cord-277665-ac8txr3h 258 32 µg µg NN cord-277665-ac8txr3h 258 33 mL mL NNP cord-277665-ac8txr3h 258 34 −1 −1 NNP cord-277665-ac8txr3h 258 35 concentrations concentration NNS cord-277665-ac8txr3h 258 36 ( ( -LRB- cord-277665-ac8txr3h 258 37 El El NNP cord-277665-ac8txr3h 258 38 - - HYPH cord-277665-ac8txr3h 258 39 Emam Emam NNP cord-277665-ac8txr3h 258 40 et et NNP cord-277665-ac8txr3h 258 41 al al NNP cord-277665-ac8txr3h 258 42 . . NNP cord-277665-ac8txr3h 258 43 , , , cord-277665-ac8txr3h 258 44 2004 2004 CD cord-277665-ac8txr3h 258 45 ) ) -RRB- cord-277665-ac8txr3h 258 46 . . . cord-277665-ac8txr3h 259 1 Adamantane Adamantane NNP cord-277665-ac8txr3h 259 2 - - HYPH cord-277665-ac8txr3h 259 3 based base VBN cord-277665-ac8txr3h 259 4 drugs drug NNS cord-277665-ac8txr3h 259 5 , , , cord-277665-ac8txr3h 259 6 namely namely RB cord-277665-ac8txr3h 259 7 , , , cord-277665-ac8txr3h 259 8 amantadine amantadine NNP cord-277665-ac8txr3h 259 9 and and CC cord-277665-ac8txr3h 259 10 tromantadine tromantadine NNP cord-277665-ac8txr3h 259 11 , , , cord-277665-ac8txr3h 259 12 are be VBP cord-277665-ac8txr3h 259 13 excreted excrete VBN cord-277665-ac8txr3h 259 14 unaltered unaltered JJ cord-277665-ac8txr3h 259 15 in in IN cord-277665-ac8txr3h 259 16 the the DT cord-277665-ac8txr3h 259 17 urine urine NN cord-277665-ac8txr3h 259 18 and and CC cord-277665-ac8txr3h 259 19 are be VBP cord-277665-ac8txr3h 259 20 not not RB cord-277665-ac8txr3h 259 21 susceptible susceptible JJ cord-277665-ac8txr3h 259 22 to to IN cord-277665-ac8txr3h 259 23 hydroxylation hydroxylation NN cord-277665-ac8txr3h 259 24 ( ( -LRB- cord-277665-ac8txr3h 259 25 Koppel Koppel NNP cord-277665-ac8txr3h 259 26 and and CC cord-277665-ac8txr3h 259 27 Tenczer Tenczer NNP cord-277665-ac8txr3h 259 28 , , , cord-277665-ac8txr3h 259 29 1985 1985 CD cord-277665-ac8txr3h 259 30 ) ) -RRB- cord-277665-ac8txr3h 259 31 . . . cord-277665-ac8txr3h 260 1 In in IN cord-277665-ac8txr3h 260 2 2005 2005 CD cord-277665-ac8txr3h 260 3 , , , cord-277665-ac8txr3h 260 4 Hodek Hodek NNP cord-277665-ac8txr3h 260 5 et et NNP cord-277665-ac8txr3h 260 6 al al NNP cord-277665-ac8txr3h 260 7 . . NNP cord-277665-ac8txr3h 260 8 discovered discover VBD cord-277665-ac8txr3h 260 9 that that IN cord-277665-ac8txr3h 260 10 adamantane adamantane NNP cord-277665-ac8txr3h 260 11 , , , cord-277665-ac8txr3h 260 12 diamantane diamantane NNP cord-277665-ac8txr3h 260 13 , , , cord-277665-ac8txr3h 260 14 triamantane triamantane NNP cord-277665-ac8txr3h 260 15 , , , cord-277665-ac8txr3h 260 16 2-isopropenyl-2-methyladamantane 2-isopropenyl-2-methyladamantane CD cord-277665-ac8txr3h 260 17 , , , cord-277665-ac8txr3h 260 18 and and CC cord-277665-ac8txr3h 260 19 3-isopropenyl-3methyldiamantane 3-isopropenyl-3methyldiamantane CD cord-277665-ac8txr3h 260 20 inhibited inhibit VBN cord-277665-ac8txr3h 260 21 cytochromes cytochrome NNS cord-277665-ac8txr3h 260 22 P450 P450 NNPS cord-277665-ac8txr3h 260 23 of of IN cord-277665-ac8txr3h 260 24 subfamily subfamily NN cord-277665-ac8txr3h 260 25 IIB IIB NNP cord-277665-ac8txr3h 260 26 by by IN cord-277665-ac8txr3h 260 27 binding bind VBG cord-277665-ac8txr3h 260 28 to to IN cord-277665-ac8txr3h 260 29 the the DT cord-277665-ac8txr3h 260 30 active active JJ cord-277665-ac8txr3h 260 31 site site NN cord-277665-ac8txr3h 260 32 and and CC cord-277665-ac8txr3h 260 33 , , , cord-277665-ac8txr3h 260 34 thus thus RB cord-277665-ac8txr3h 260 35 , , , cord-277665-ac8txr3h 260 36 could could MD cord-277665-ac8txr3h 260 37 be be VB cord-277665-ac8txr3h 260 38 potent potent JJ cord-277665-ac8txr3h 260 39 inhibitors inhibitor NNS cord-277665-ac8txr3h 260 40 for for IN cord-277665-ac8txr3h 260 41 hepatic hepatic JJ cord-277665-ac8txr3h 260 42 oxidative oxidative JJ cord-277665-ac8txr3h 260 43 drug drug NN cord-277665-ac8txr3h 260 44 metabolism metabolism NN cord-277665-ac8txr3h 260 45 in in IN cord-277665-ac8txr3h 260 46 humans human NNS cord-277665-ac8txr3h 260 47 . . . cord-277665-ac8txr3h 261 1 Theoretical theoretical JJ cord-277665-ac8txr3h 261 2 and and CC cord-277665-ac8txr3h 261 3 experimental experimental JJ cord-277665-ac8txr3h 261 4 values value NNS cord-277665-ac8txr3h 261 5 of of IN cord-277665-ac8txr3h 261 6 the the DT cord-277665-ac8txr3h 261 7 dissociation dissociation NN cord-277665-ac8txr3h 261 8 constant constant NN cord-277665-ac8txr3h 261 9 of of IN cord-277665-ac8txr3h 261 10 cytochrome cytochrome NN cord-277665-ac8txr3h 261 11 P450 p450 JJ cord-277665-ac8txr3h 261 12 complexes complex NNS cord-277665-ac8txr3h 261 13 with with IN cord-277665-ac8txr3h 261 14 the the DT cord-277665-ac8txr3h 261 15 diamondoids diamondoid NNS cord-277665-ac8txr3h 261 16 were be VBD cord-277665-ac8txr3h 261 17 in in IN cord-277665-ac8txr3h 261 18 good good JJ cord-277665-ac8txr3h 261 19 agreement agreement NN cord-277665-ac8txr3h 261 20 and and CC cord-277665-ac8txr3h 261 21 confirmed confirm VBD cord-277665-ac8txr3h 261 22 the the DT cord-277665-ac8txr3h 261 23 high high JJ cord-277665-ac8txr3h 261 24 potency potency NN cord-277665-ac8txr3h 261 25 of of IN cord-277665-ac8txr3h 261 26 identified identify VBN cord-277665-ac8txr3h 261 27 inhibitors inhibitor NNS cord-277665-ac8txr3h 261 28 . . . cord-277665-ac8txr3h 262 1 Bananins bananin NNS cord-277665-ac8txr3h 262 2 , , , cord-277665-ac8txr3h 262 3 the the DT cord-277665-ac8txr3h 262 4 antiviral antiviral JJ cord-277665-ac8txr3h 262 5 agents agent NNS cord-277665-ac8txr3h 262 6 that that WDT cord-277665-ac8txr3h 262 7 possess possess VBP cord-277665-ac8txr3h 262 8 a a DT cord-277665-ac8txr3h 262 9 trioxaadamantane trioxaadamantane NN cord-277665-ac8txr3h 262 10 moiety moiety NN cord-277665-ac8txr3h 262 11 attached attach VBN cord-277665-ac8txr3h 262 12 to to IN cord-277665-ac8txr3h 262 13 a a DT cord-277665-ac8txr3h 262 14 pyridoxal pyridoxal NN cord-277665-ac8txr3h 262 15 derivative derivative JJ cord-277665-ac8txr3h 262 16 , , , cord-277665-ac8txr3h 262 17 were be VBD cord-277665-ac8txr3h 262 18 shown show VBN cord-277665-ac8txr3h 262 19 to to TO cord-277665-ac8txr3h 262 20 be be VB cord-277665-ac8txr3h 262 21 potent potent JJ cord-277665-ac8txr3h 262 22 inhibitors inhibitor NNS cord-277665-ac8txr3h 262 23 of of IN cord-277665-ac8txr3h 262 24 the the DT cord-277665-ac8txr3h 262 25 SARS SARS NNP cord-277665-ac8txr3h 262 26 ( ( -LRB- cord-277665-ac8txr3h 262 27 severe severe JJ cord-277665-ac8txr3h 262 28 acute acute JJ cord-277665-ac8txr3h 262 29 respiratory respiratory JJ cord-277665-ac8txr3h 262 30 syndrome syndrome NN cord-277665-ac8txr3h 262 31 ) ) -RRB- cord-277665-ac8txr3h 262 32 coronavirus coronavirus NN cord-277665-ac8txr3h 262 33 helicase helicase NN cord-277665-ac8txr3h 262 34 and and CC cord-277665-ac8txr3h 262 35 can can MD cord-277665-ac8txr3h 262 36 prevent prevent VB cord-277665-ac8txr3h 262 37 replication replication NN cord-277665-ac8txr3h 262 38 of of IN cord-277665-ac8txr3h 262 39 animal animal NN cord-277665-ac8txr3h 262 40 SCV SCV NNP cord-277665-ac8txr3h 262 41 ( ( -LRB- cord-277665-ac8txr3h 262 42 SARS SARS NNP cord-277665-ac8txr3h 262 43 - - HYPH cord-277665-ac8txr3h 262 44 related relate VBN cord-277665-ac8txr3h 262 45 coronavirus coronavirus NN cord-277665-ac8txr3h 262 46 ) ) -RRB- cord-277665-ac8txr3h 263 1 ( ( -LRB- cord-277665-ac8txr3h 263 2 Tanner Tanner NNP cord-277665-ac8txr3h 263 3 et et NNP cord-277665-ac8txr3h 263 4 al al NNP cord-277665-ac8txr3h 263 5 . . NNP cord-277665-ac8txr3h 263 6 , , , cord-277665-ac8txr3h 263 7 2005 2005 CD cord-277665-ac8txr3h 263 8 ) ) -RRB- cord-277665-ac8txr3h 263 9 . . . cord-277665-ac8txr3h 264 1 Recently recently RB cord-277665-ac8txr3h 264 2 , , , cord-277665-ac8txr3h 264 3 the the DT cord-277665-ac8txr3h 264 4 adamantane adamantane NNP cord-277665-ac8txr3h 264 5 derivatives derivative NNS cord-277665-ac8txr3h 264 6 have have VBP cord-277665-ac8txr3h 264 7 been be VBN cord-277665-ac8txr3h 264 8 identified identify VBN cord-277665-ac8txr3h 264 9 as as IN cord-277665-ac8txr3h 264 10 the the DT cord-277665-ac8txr3h 264 11 potential potential JJ cord-277665-ac8txr3h 264 12 drugs drug NNS cord-277665-ac8txr3h 264 13 acting act VBG cord-277665-ac8txr3h 264 14 on on IN cord-277665-ac8txr3h 264 15 the the DT cord-277665-ac8txr3h 264 16 P2X(7 P2X(7 NNP cord-277665-ac8txr3h 264 17 ) ) -RRB- cord-277665-ac8txr3h 264 18 receptor receptor NN cord-277665-ac8txr3h 264 19 , , , cord-277665-ac8txr3h 264 20 which which WDT cord-277665-ac8txr3h 264 21 is be VBZ cord-277665-ac8txr3h 264 22 involved involve VBN cord-277665-ac8txr3h 264 23 in in IN cord-277665-ac8txr3h 264 24 signaling signal VBG cord-277665-ac8txr3h 264 25 in in IN cord-277665-ac8txr3h 264 26 many many JJ cord-277665-ac8txr3h 264 27 inflammatory inflammatory JJ cord-277665-ac8txr3h 264 28 processes process NNS cord-277665-ac8txr3h 264 29 ( ( -LRB- cord-277665-ac8txr3h 264 30 cytokine cytokine NN cord-277665-ac8txr3h 264 31 release release NN cord-277665-ac8txr3h 264 32 , , , cord-277665-ac8txr3h 264 33 NO no DT cord-277665-ac8txr3h 264 34 generation generation NN cord-277665-ac8txr3h 264 35 , , , cord-277665-ac8txr3h 264 36 cytotoxicity cytotoxicity NN cord-277665-ac8txr3h 264 37 , , , cord-277665-ac8txr3h 264 38 killing killing NN cord-277665-ac8txr3h 264 39 of of IN cord-277665-ac8txr3h 264 40 intracellular intracellular JJ cord-277665-ac8txr3h 264 41 pathogens pathogen NNS cord-277665-ac8txr3h 264 42 ) ) -RRB- cord-277665-ac8txr3h 265 1 ( ( -LRB- cord-277665-ac8txr3h 265 2 Baraldi Baraldi NNP cord-277665-ac8txr3h 265 3 et et NNP cord-277665-ac8txr3h 265 4 al al NNP cord-277665-ac8txr3h 265 5 . . NNP cord-277665-ac8txr3h 265 6 , , , cord-277665-ac8txr3h 265 7 2004 2004 CD cord-277665-ac8txr3h 265 8 ; ; : cord-277665-ac8txr3h 265 9 Romagnoli Romagnoli NNP cord-277665-ac8txr3h 265 10 et et FW cord-277665-ac8txr3h 265 11 al al NNP cord-277665-ac8txr3h 265 12 . . NNP cord-277665-ac8txr3h 265 13 , , , cord-277665-ac8txr3h 265 14 2005 2005 CD cord-277665-ac8txr3h 265 15 ) ) -RRB- cord-277665-ac8txr3h 265 16 . . . cord-277665-ac8txr3h 266 1 Because because IN cord-277665-ac8txr3h 266 2 ND ND NNP cord-277665-ac8txr3h 266 3 is be VBZ cord-277665-ac8txr3h 266 4 not not RB cord-277665-ac8txr3h 266 5 mutagenic mutagenic JJ cord-277665-ac8txr3h 266 6 or or CC cord-277665-ac8txr3h 266 7 toxic toxic JJ cord-277665-ac8txr3h 266 8 ( ( -LRB- cord-277665-ac8txr3h 266 9 oral oral JJ cord-277665-ac8txr3h 266 10 LD50 LD50 NNP cord-277665-ac8txr3h 266 11 value value NN cord-277665-ac8txr3h 266 12 for for IN cord-277665-ac8txr3h 266 13 rats rat NNS cord-277665-ac8txr3h 266 14 is be VBZ cord-277665-ac8txr3h 266 15 7 7 CD cord-277665-ac8txr3h 266 16 g g NN cord-277665-ac8txr3h 266 17 kg kg NNP cord-277665-ac8txr3h 266 18 −1 −1 NNP cord-277665-ac8txr3h 266 19 ) ) -RRB- cord-277665-ac8txr3h 266 20 , , , cord-277665-ac8txr3h 266 21 can can MD cord-277665-ac8txr3h 266 22 neutralize neutralize VB cord-277665-ac8txr3h 266 23 free free JJ cord-277665-ac8txr3h 266 24 radicals radical NNS cord-277665-ac8txr3h 266 25 , , , cord-277665-ac8txr3h 266 26 and and CC cord-277665-ac8txr3h 266 27 possesses possess VBZ cord-277665-ac8txr3h 266 28 a a DT cord-277665-ac8txr3h 266 29 very very RB cord-277665-ac8txr3h 266 30 large large JJ cord-277665-ac8txr3h 266 31 surface surface NN cord-277665-ac8txr3h 266 32 area area NN cord-277665-ac8txr3h 266 33 , , , cord-277665-ac8txr3h 266 34 it -PRON- PRP cord-277665-ac8txr3h 266 35 was be VBD cord-277665-ac8txr3h 266 36 suggested suggest VBN cord-277665-ac8txr3h 266 37 that that IN cord-277665-ac8txr3h 266 38 detonation detonation NN cord-277665-ac8txr3h 266 39 ND ND NNP cord-277665-ac8txr3h 266 40 particles particle NNS cord-277665-ac8txr3h 266 41 may may MD cord-277665-ac8txr3h 266 42 have have VB cord-277665-ac8txr3h 266 43 some some DT cord-277665-ac8txr3h 266 44 antitumor antitumor JJ cord-277665-ac8txr3h 266 45 activity activity NN cord-277665-ac8txr3h 266 46 ( ( -LRB- cord-277665-ac8txr3h 266 47 Dolmatov Dolmatov NNP cord-277665-ac8txr3h 266 48 and and CC cord-277665-ac8txr3h 266 49 Kostrova Kostrova NNP cord-277665-ac8txr3h 266 50 , , , cord-277665-ac8txr3h 266 51 2000 2000 CD cord-277665-ac8txr3h 266 52 ; ; : cord-277665-ac8txr3h 266 53 see see VB cord-277665-ac8txr3h 266 54 also also RB cord-277665-ac8txr3h 266 55 Chapter chapter NN cord-277665-ac8txr3h 266 56 13 13 CD cord-277665-ac8txr3h 266 57 ) ) -RRB- cord-277665-ac8txr3h 266 58 . . . cord-277665-ac8txr3h 267 1 Indeed indeed RB cord-277665-ac8txr3h 267 2 , , , cord-277665-ac8txr3h 267 3 mice mouse NNS cord-277665-ac8txr3h 267 4 with with IN cord-277665-ac8txr3h 267 5 Erlich Erlich NNP cord-277665-ac8txr3h 267 6 ascetic ascetic JJ cord-277665-ac8txr3h 267 7 carcinoma carcinoma NN cord-277665-ac8txr3h 267 8 that that WDT cord-277665-ac8txr3h 267 9 were be VBD cord-277665-ac8txr3h 267 10 given give VBN cord-277665-ac8txr3h 267 11 supplements supplement NNS cord-277665-ac8txr3h 267 12 with with IN cord-277665-ac8txr3h 267 13 the the DT cord-277665-ac8txr3h 267 14 ND ND NNP cord-277665-ac8txr3h 267 15 suspensions suspension NNS cord-277665-ac8txr3h 267 16 were be VBD cord-277665-ac8txr3h 267 17 more more RBR cord-277665-ac8txr3h 267 18 active active JJ cord-277665-ac8txr3h 267 19 and and CC cord-277665-ac8txr3h 267 20 lived live VBD cord-277665-ac8txr3h 267 21 almost almost RB cord-277665-ac8txr3h 267 22 40 40 CD cord-277665-ac8txr3h 267 23 % % NN cord-277665-ac8txr3h 267 24 longer long JJR cord-277665-ac8txr3h 267 25 than than IN cord-277665-ac8txr3h 267 26 non non JJ cord-277665-ac8txr3h 267 27 - - JJ cord-277665-ac8txr3h 267 28 treated treat VBN cord-277665-ac8txr3h 267 29 animals animal NNS cord-277665-ac8txr3h 267 30 . . . cord-277665-ac8txr3h 268 1 In in IN cord-277665-ac8txr3h 268 2 2001 2001 CD cord-277665-ac8txr3h 268 3 , , , cord-277665-ac8txr3h 268 4 Dolmatov Dolmatov NNP cord-277665-ac8txr3h 268 5 reported report VBD cord-277665-ac8txr3h 268 6 the the DT cord-277665-ac8txr3h 268 7 results result NNS cord-277665-ac8txr3h 268 8 of of IN cord-277665-ac8txr3h 268 9 a a DT cord-277665-ac8txr3h 268 10 new new JJ cord-277665-ac8txr3h 268 11 medical medical JJ cord-277665-ac8txr3h 268 12 study study NN cord-277665-ac8txr3h 268 13 of of IN cord-277665-ac8txr3h 268 14 the the DT cord-277665-ac8txr3h 268 15 possible possible JJ cord-277665-ac8txr3h 268 16 oral oral JJ cord-277665-ac8txr3h 268 17 administration administration NN cord-277665-ac8txr3h 268 18 of of IN cord-277665-ac8txr3h 268 19 water water NN cord-277665-ac8txr3h 268 20 suspensions suspension NNS cord-277665-ac8txr3h 268 21 of of IN cord-277665-ac8txr3h 268 22 NDs nd NNS cord-277665-ac8txr3h 268 23 to to TO cord-277665-ac8txr3h 268 24 terminally terminally RB cord-277665-ac8txr3h 268 25 ill ill JJ cord-277665-ac8txr3h 268 26 cancer cancer NN cord-277665-ac8txr3h 268 27 patients patient NNS cord-277665-ac8txr3h 268 28 . . . cord-277665-ac8txr3h 269 1 The the DT cord-277665-ac8txr3h 269 2 oral oral JJ cord-277665-ac8txr3h 269 3 administrations administration NNS cord-277665-ac8txr3h 269 4 of of IN cord-277665-ac8txr3h 269 5 ND ND NNP cord-277665-ac8txr3h 269 6 did do VBD cord-277665-ac8txr3h 269 7 not not RB cord-277665-ac8txr3h 269 8 result result VB cord-277665-ac8txr3h 269 9 in in IN cord-277665-ac8txr3h 269 10 any any DT cord-277665-ac8txr3h 269 11 side side NN cord-277665-ac8txr3h 269 12 effects effect NNS cord-277665-ac8txr3h 269 13 and and CC cord-277665-ac8txr3h 269 14 , , , cord-277665-ac8txr3h 269 15 moreover moreover RB cord-277665-ac8txr3h 269 16 , , , cord-277665-ac8txr3h 269 17 were be VBD cord-277665-ac8txr3h 269 18 moderately moderately RB cord-277665-ac8txr3h 269 19 beneficial beneficial JJ cord-277665-ac8txr3h 269 20 in in IN cord-277665-ac8txr3h 269 21 some some DT cord-277665-ac8txr3h 269 22 cases case NNS cord-277665-ac8txr3h 269 23 . . . cord-277665-ac8txr3h 270 1 Diamond Diamond NNP cord-277665-ac8txr3h 270 2 has have VBZ cord-277665-ac8txr3h 270 3 the the DT cord-277665-ac8txr3h 270 4 outstanding outstanding JJ cord-277665-ac8txr3h 270 5 reputation reputation NN cord-277665-ac8txr3h 270 6 of of IN cord-277665-ac8txr3h 270 7 a a DT cord-277665-ac8txr3h 270 8 chemically chemically RB cord-277665-ac8txr3h 270 9 inert inert JJ cord-277665-ac8txr3h 270 10 and and CC cord-277665-ac8txr3h 270 11 uniquely uniquely RB cord-277665-ac8txr3h 270 12 biologically biologically RB cord-277665-ac8txr3h 270 13 compatible compatible JJ cord-277665-ac8txr3h 270 14 material material NN cord-277665-ac8txr3h 270 15 that that WDT cord-277665-ac8txr3h 270 16 has have VBZ cord-277665-ac8txr3h 270 17 found find VBN cord-277665-ac8txr3h 270 18 a a DT cord-277665-ac8txr3h 270 19 number number NN cord-277665-ac8txr3h 270 20 of of IN cord-277665-ac8txr3h 270 21 applications application NNS cord-277665-ac8txr3h 270 22 in in IN cord-277665-ac8txr3h 270 23 medicine medicine NN cord-277665-ac8txr3h 270 24 ( ( -LRB- cord-277665-ac8txr3h 270 25 Freitas Freitas NNP cord-277665-ac8txr3h 270 26 , , , cord-277665-ac8txr3h 270 27 2003 2003 CD cord-277665-ac8txr3h 270 28 ) ) -RRB- cord-277665-ac8txr3h 270 29 . . . cord-277665-ac8txr3h 271 1 Diamond diamond NN cord-277665-ac8txr3h 271 2 is be VBZ cord-277665-ac8txr3h 271 3 biocompatible biocompatible JJ cord-277665-ac8txr3h 271 4 in in IN cord-277665-ac8txr3h 271 5 both both DT cord-277665-ac8txr3h 271 6 bulk bulk NN cord-277665-ac8txr3h 271 7 and and CC cord-277665-ac8txr3h 271 8 particulate particulate NN cord-277665-ac8txr3h 271 9 forms form NNS cord-277665-ac8txr3h 271 10 . . . cord-277665-ac8txr3h 272 1 In in IN cord-277665-ac8txr3h 272 2 orthopedic orthopedic NN cord-277665-ac8txr3h 272 3 surgery surgery NN cord-277665-ac8txr3h 272 4 the the DT cord-277665-ac8txr3h 272 5 use use NN cord-277665-ac8txr3h 272 6 of of IN cord-277665-ac8txr3h 272 7 a a DT cord-277665-ac8txr3h 272 8 diamond diamond NN cord-277665-ac8txr3h 272 9 coating coating NN cord-277665-ac8txr3h 272 10 on on IN cord-277665-ac8txr3h 272 11 the the DT cord-277665-ac8txr3h 272 12 metallic metallic JJ cord-277665-ac8txr3h 272 13 components component NNS cord-277665-ac8txr3h 272 14 reduces reduce VBZ cord-277665-ac8txr3h 272 15 generation generation NN cord-277665-ac8txr3h 272 16 of of IN cord-277665-ac8txr3h 272 17 macrophages macrophage NNS cord-277665-ac8txr3h 272 18 and and CC cord-277665-ac8txr3h 272 19 improves improve VBZ cord-277665-ac8txr3h 272 20 the the DT cord-277665-ac8txr3h 272 21 wearability wearability NN cord-277665-ac8txr3h 272 22 of of IN cord-277665-ac8txr3h 272 23 devices device NNS cord-277665-ac8txr3h 272 24 ( ( -LRB- cord-277665-ac8txr3h 272 25 Santavirta Santavirta NNP cord-277665-ac8txr3h 272 26 et et NNP cord-277665-ac8txr3h 272 27 al al NNP cord-277665-ac8txr3h 272 28 . . NNP cord-277665-ac8txr3h 272 29 , , , cord-277665-ac8txr3h 272 30 1999 1999 CD cord-277665-ac8txr3h 272 31 ) ) -RRB- cord-277665-ac8txr3h 272 32 . . . cord-277665-ac8txr3h 273 1 In in IN cord-277665-ac8txr3h 273 2 addition addition NN cord-277665-ac8txr3h 273 3 , , , cord-277665-ac8txr3h 273 4 nanocrystalline nanocrystalline NNP cord-277665-ac8txr3h 273 5 diamond diamond NNP cord-277665-ac8txr3h 273 6 films films NNPS cord-277665-ac8txr3h 273 7 show show VBP cord-277665-ac8txr3h 273 8 an an DT cord-277665-ac8txr3h 273 9 excellent excellent JJ cord-277665-ac8txr3h 273 10 resistance resistance NN cord-277665-ac8txr3h 273 11 to to IN cord-277665-ac8txr3h 273 12 bacterial bacterial JJ cord-277665-ac8txr3h 273 13 colonization colonization NN cord-277665-ac8txr3h 274 1 ( ( -LRB- cord-277665-ac8txr3h 274 2 Jakubowski Jakubowski NNP cord-277665-ac8txr3h 274 3 et et NNP cord-277665-ac8txr3h 274 4 al al NNP cord-277665-ac8txr3h 274 5 . . . cord-277665-ac8txr3h 275 1 , , , cord-277665-ac8txr3h 275 2 2004 2004 CD cord-277665-ac8txr3h 275 3 ) ) -RRB- cord-277665-ac8txr3h 275 4 . . . cord-277665-ac8txr3h 276 1 The the DT cord-277665-ac8txr3h 276 2 diamond diamond NN cord-277665-ac8txr3h 276 3 - - HYPH cord-277665-ac8txr3h 276 4 like like JJ cord-277665-ac8txr3h 276 5 carbon carbon NN cord-277665-ac8txr3h 276 6 coating coating NN cord-277665-ac8txr3h 276 7 is be VBZ cord-277665-ac8txr3h 276 8 also also RB cord-277665-ac8txr3h 276 9 very very RB cord-277665-ac8txr3h 276 10 inert inert JJ cord-277665-ac8txr3h 276 11 and and CC cord-277665-ac8txr3h 276 12 particularly particularly RB cord-277665-ac8txr3h 276 13 suitable suitable JJ cord-277665-ac8txr3h 276 14 for for IN cord-277665-ac8txr3h 276 15 use use NN cord-277665-ac8txr3h 276 16 in in IN cord-277665-ac8txr3h 276 17 orthopedic orthopedic JJ cord-277665-ac8txr3h 276 18 implants implant NNS cord-277665-ac8txr3h 276 19 . . . cord-277665-ac8txr3h 277 1 In in IN cord-277665-ac8txr3h 277 2 an an DT cord-277665-ac8txr3h 277 3 early early JJ cord-277665-ac8txr3h 277 4 , , , cord-277665-ac8txr3h 277 5 pioneering pioneering JJ cord-277665-ac8txr3h 277 6 study study NN cord-277665-ac8txr3h 277 7 Thomson Thomson NNP cord-277665-ac8txr3h 277 8 et et NNP cord-277665-ac8txr3h 277 9 al al NNP cord-277665-ac8txr3h 277 10 . . . cord-277665-ac8txr3h 278 1 ( ( -LRB- cord-277665-ac8txr3h 278 2 1991 1991 CD cord-277665-ac8txr3h 278 3 ) ) -RRB- cord-277665-ac8txr3h 278 4 grew grow VBD cord-277665-ac8txr3h 278 5 mouse mouse NN cord-277665-ac8txr3h 278 6 peritoneal peritoneal JJ cord-277665-ac8txr3h 278 7 macrophages macrophage NNS cord-277665-ac8txr3h 278 8 and and CC cord-277665-ac8txr3h 278 9 fibroblasts fibroblast NNS cord-277665-ac8txr3h 278 10 on on IN cord-277665-ac8txr3h 278 11 tissue tissue NN cord-277665-ac8txr3h 278 12 culture culture NN cord-277665-ac8txr3h 278 13 plates plate NNS cord-277665-ac8txr3h 278 14 coated coat VBN cord-277665-ac8txr3h 278 15 with with IN cord-277665-ac8txr3h 278 16 0.4 0.4 CD cord-277665-ac8txr3h 278 17 µm µm NN cord-277665-ac8txr3h 278 18 of of IN cord-277665-ac8txr3h 278 19 an an DT cord-277665-ac8txr3h 278 20 amorphous amorphous JJ cord-277665-ac8txr3h 278 21 diamond diamond NN cord-277665-ac8txr3h 278 22 - - HYPH cord-277665-ac8txr3h 278 23 like like JJ cord-277665-ac8txr3h 278 24 carbon carbon NN cord-277665-ac8txr3h 278 25 layer layer NN cord-277665-ac8txr3h 278 26 and and CC cord-277665-ac8txr3h 278 27 assessed assess VBD cord-277665-ac8txr3h 278 28 the the DT cord-277665-ac8txr3h 278 29 biocompatibility biocompatibility NN cord-277665-ac8txr3h 278 30 both both DT cord-277665-ac8txr3h 278 31 biochemically biochemically RB cord-277665-ac8txr3h 278 32 and and CC cord-277665-ac8txr3h 278 33 morphologically morphologically RB cord-277665-ac8txr3h 278 34 . . . cord-277665-ac8txr3h 279 1 The the DT cord-277665-ac8txr3h 279 2 diamond diamond NN cord-277665-ac8txr3h 279 3 - - HYPH cord-277665-ac8txr3h 279 4 like like JJ cord-277665-ac8txr3h 279 5 carbon carbon NN cord-277665-ac8txr3h 279 6 coating coating NN cord-277665-ac8txr3h 279 7 caused cause VBD cord-277665-ac8txr3h 279 8 no no DT cord-277665-ac8txr3h 279 9 adverse adverse JJ cord-277665-ac8txr3h 279 10 effects effect NNS cord-277665-ac8txr3h 279 11 on on IN cord-277665-ac8txr3h 279 12 cells cell NNS cord-277665-ac8txr3h 279 13 in in IN cord-277665-ac8txr3h 279 14 the the DT cord-277665-ac8txr3h 279 15 culture culture NN cord-277665-ac8txr3h 279 16 . . . cord-277665-ac8txr3h 280 1 Recently recently RB cord-277665-ac8txr3h 280 2 diamond diamond NN cord-277665-ac8txr3h 280 3 - - HYPH cord-277665-ac8txr3h 280 4 like like JJ cord-277665-ac8txr3h 280 5 carbon carbon NN cord-277665-ac8txr3h 280 6 films film NNS cord-277665-ac8txr3h 280 7 have have VBP cord-277665-ac8txr3h 280 8 been be VBN cord-277665-ac8txr3h 280 9 reexamined reexamine VBN cord-277665-ac8txr3h 280 10 and and CC cord-277665-ac8txr3h 280 11 it -PRON- PRP cord-277665-ac8txr3h 280 12 was be VBD cord-277665-ac8txr3h 280 13 reported report VBN cord-277665-ac8txr3h 280 14 that that IN cord-277665-ac8txr3h 280 15 they -PRON- PRP cord-277665-ac8txr3h 280 16 have have VBP cord-277665-ac8txr3h 280 17 good good JJ cord-277665-ac8txr3h 280 18 biocompatibility biocompatibility NN cord-277665-ac8txr3h 280 19 and and CC cord-277665-ac8txr3h 280 20 high high JJ cord-277665-ac8txr3h 280 21 corrosion corrosion NN cord-277665-ac8txr3h 280 22 resistance resistance NN cord-277665-ac8txr3h 281 1 ( ( -LRB- cord-277665-ac8txr3h 281 2 Kim Kim NNP cord-277665-ac8txr3h 281 3 et et NNP cord-277665-ac8txr3h 281 4 al al NNP cord-277665-ac8txr3h 281 5 . . NNP cord-277665-ac8txr3h 281 6 , , , cord-277665-ac8txr3h 281 7 2005 2005 CD cord-277665-ac8txr3h 281 8 ) ) -RRB- cord-277665-ac8txr3h 281 9 . . . cord-277665-ac8txr3h 282 1 Additional additional JJ cord-277665-ac8txr3h 282 2 evidence evidence NN cord-277665-ac8txr3h 282 3 of of IN cord-277665-ac8txr3h 282 4 diamond diamond NN cord-277665-ac8txr3h 282 5 biocompatibility biocompatibility NN cord-277665-ac8txr3h 282 6 came come VBD cord-277665-ac8txr3h 282 7 from from IN cord-277665-ac8txr3h 282 8 Zheng Zheng NNP cord-277665-ac8txr3h 282 9 et et FW cord-277665-ac8txr3h 282 10 al al NNP cord-277665-ac8txr3h 282 11 . . . cord-277665-ac8txr3h 283 1 ( ( -LRB- cord-277665-ac8txr3h 283 2 2005 2005 CD cord-277665-ac8txr3h 283 3 ) ) -RRB- cord-277665-ac8txr3h 283 4 who who WP cord-277665-ac8txr3h 283 5 fabricated fabricate VBD cord-277665-ac8txr3h 283 6 nanocrystalline nanocrystalline NNP cord-277665-ac8txr3h 283 7 diamond diamond NN cord-277665-ac8txr3h 283 8 films film NNS cord-277665-ac8txr3h 283 9 ( ( -LRB- cord-277665-ac8txr3h 283 10 NDFs NDFs NNP cord-277665-ac8txr3h 283 11 ) ) -RRB- cord-277665-ac8txr3h 283 12 on on IN cord-277665-ac8txr3h 283 13 optical optical JJ cord-277665-ac8txr3h 283 14 glass glass NN cord-277665-ac8txr3h 283 15 using use VBG cord-277665-ac8txr3h 283 16 microwave microwave NN cord-277665-ac8txr3h 283 17 plasma plasma NN cord-277665-ac8txr3h 283 18 assisted assist VBD cord-277665-ac8txr3h 283 19 CVD CVD NNP cord-277665-ac8txr3h 283 20 and and CC cord-277665-ac8txr3h 283 21 used use VBD cord-277665-ac8txr3h 283 22 osteoblast osteoblast JJ cord-277665-ac8txr3h 283 23 cell cell NN cord-277665-ac8txr3h 283 24 cultures culture NNS cord-277665-ac8txr3h 283 25 and and CC cord-277665-ac8txr3h 283 26 platelet platelet NN cord-277665-ac8txr3h 283 27 adhesion adhesion NN cord-277665-ac8txr3h 283 28 tests test NNS cord-277665-ac8txr3h 283 29 for for IN cord-277665-ac8txr3h 283 30 in in FW cord-277665-ac8txr3h 283 31 vitro vitro FW cord-277665-ac8txr3h 283 32 evaluation evaluation NN cord-277665-ac8txr3h 283 33 of of IN cord-277665-ac8txr3h 283 34 biocompatibility biocompatibility NN cord-277665-ac8txr3h 283 35 of of IN cord-277665-ac8txr3h 283 36 NDFs ndf NNS cord-277665-ac8txr3h 283 37 . . . cord-277665-ac8txr3h 284 1 Their -PRON- PRP$ cord-277665-ac8txr3h 284 2 results result NNS cord-277665-ac8txr3h 284 3 indicated indicate VBD cord-277665-ac8txr3h 284 4 that that IN cord-277665-ac8txr3h 284 5 the the DT cord-277665-ac8txr3h 284 6 diamond diamond NN cord-277665-ac8txr3h 284 7 films film NNS cord-277665-ac8txr3h 284 8 exhibit exhibit VBP cord-277665-ac8txr3h 284 9 good good JJ cord-277665-ac8txr3h 284 10 tissue tissue NN cord-277665-ac8txr3h 284 11 compatibility compatibility NN cord-277665-ac8txr3h 284 12 and and CC cord-277665-ac8txr3h 284 13 hemocompatibility hemocompatibility NN cord-277665-ac8txr3h 284 14 , , , cord-277665-ac8txr3h 284 15 which which WDT cord-277665-ac8txr3h 284 16 makes make VBZ cord-277665-ac8txr3h 284 17 them -PRON- PRP cord-277665-ac8txr3h 284 18 very very RB cord-277665-ac8txr3h 284 19 suitable suitable JJ cord-277665-ac8txr3h 284 20 for for IN cord-277665-ac8txr3h 284 21 biomedical biomedical JJ cord-277665-ac8txr3h 284 22 applications application NNS cord-277665-ac8txr3h 284 23 . . . cord-277665-ac8txr3h 285 1 The the DT cord-277665-ac8txr3h 285 2 excellent excellent JJ cord-277665-ac8txr3h 285 3 chemical chemical NN cord-277665-ac8txr3h 285 4 inertness inertness NN cord-277665-ac8txr3h 285 5 and and CC cord-277665-ac8txr3h 285 6 smoothness smoothness NN cord-277665-ac8txr3h 285 7 of of IN cord-277665-ac8txr3h 285 8 NDFs ndf NNS cord-277665-ac8txr3h 285 9 made make VBD cord-277665-ac8txr3h 285 10 them -PRON- PRP cord-277665-ac8txr3h 285 11 a a DT cord-277665-ac8txr3h 285 12 promising promising JJ cord-277665-ac8txr3h 285 13 material material NN cord-277665-ac8txr3h 285 14 for for IN cord-277665-ac8txr3h 285 15 medical medical JJ cord-277665-ac8txr3h 285 16 implants implant NNS cord-277665-ac8txr3h 285 17 , , , cord-277665-ac8txr3h 285 18 cardiovascular cardiovascular JJ cord-277665-ac8txr3h 285 19 surgery surgery NN cord-277665-ac8txr3h 285 20 , , , cord-277665-ac8txr3h 285 21 and and CC cord-277665-ac8txr3h 285 22 coating coating NN cord-277665-ac8txr3h 285 23 of of IN cord-277665-ac8txr3h 285 24 artificial artificial JJ cord-277665-ac8txr3h 285 25 heart heart NN cord-277665-ac8txr3h 285 26 valves valve NNS cord-277665-ac8txr3h 286 1 ( ( -LRB- cord-277665-ac8txr3h 286 2 Mitura Mitura NNP cord-277665-ac8txr3h 286 3 et et NNP cord-277665-ac8txr3h 286 4 al al NNP cord-277665-ac8txr3h 286 5 . . NNP cord-277665-ac8txr3h 286 6 , , , cord-277665-ac8txr3h 286 7 1996 1996 CD cord-277665-ac8txr3h 286 8 ; ; : cord-277665-ac8txr3h 286 9 1999 1999 CD cord-277665-ac8txr3h 286 10 ) ) -RRB- cord-277665-ac8txr3h 286 11 . . . cord-277665-ac8txr3h 287 1 In in IN cord-277665-ac8txr3h 287 2 2004 2004 CD cord-277665-ac8txr3h 287 3 Specht Specht NNP cord-277665-ac8txr3h 287 4 et et NNP cord-277665-ac8txr3h 287 5 al al NNP cord-277665-ac8txr3h 287 6 . . NNP cord-277665-ac8txr3h 287 7 were be VBD cord-277665-ac8txr3h 287 8 able able JJ cord-277665-ac8txr3h 287 9 to to TO cord-277665-ac8txr3h 287 10 demonstrate demonstrate VB cord-277665-ac8txr3h 287 11 the the DT cord-277665-ac8txr3h 287 12 ordered order VBN cord-277665-ac8txr3h 287 13 growth growth NN cord-277665-ac8txr3h 287 14 of of IN cord-277665-ac8txr3h 287 15 mammalian mammalian JJ cord-277665-ac8txr3h 287 16 neurons neuron NNS cord-277665-ac8txr3h 287 17 on on IN cord-277665-ac8txr3h 287 18 diamond diamond NN cord-277665-ac8txr3h 287 19 . . . cord-277665-ac8txr3h 288 1 To to TO cord-277665-ac8txr3h 288 2 accomplish accomplish VB cord-277665-ac8txr3h 288 3 this this DT cord-277665-ac8txr3h 288 4 the the DT cord-277665-ac8txr3h 288 5 researchers researcher NNS cord-277665-ac8txr3h 288 6 patterned pattern VBD cord-277665-ac8txr3h 288 7 proteins protein NNS cord-277665-ac8txr3h 288 8 on on IN cord-277665-ac8txr3h 288 9 diamond diamond NN cord-277665-ac8txr3h 288 10 surfaces surface NNS cord-277665-ac8txr3h 288 11 by by IN cord-277665-ac8txr3h 288 12 micro micro JJ cord-277665-ac8txr3h 288 13 - - JJ cord-277665-ac8txr3h 288 14 contact contact JJ cord-277665-ac8txr3h 288 15 printing printing NN cord-277665-ac8txr3h 288 16 and and CC cord-277665-ac8txr3h 288 17 cultured cultured JJ cord-277665-ac8txr3h 288 18 mouse mouse NN cord-277665-ac8txr3h 288 19 cortical cortical JJ cord-277665-ac8txr3h 288 20 neurons neuron NNS cord-277665-ac8txr3h 288 21 on on IN cord-277665-ac8txr3h 288 22 these these DT cord-277665-ac8txr3h 288 23 substrates substrate NNS cord-277665-ac8txr3h 288 24 . . . cord-277665-ac8txr3h 289 1 The the DT cord-277665-ac8txr3h 289 2 diamond diamond NN cord-277665-ac8txr3h 289 3 biocompatibility biocompatibility NN cord-277665-ac8txr3h 289 4 and and CC cord-277665-ac8txr3h 289 5 the the DT cord-277665-ac8txr3h 289 6 suitability suitability NN cord-277665-ac8txr3h 289 7 of of IN cord-277665-ac8txr3h 289 8 neuron neuron NN cord-277665-ac8txr3h 289 9 interfacing interface VBG cord-277665-ac8txr3h 289 10 with with IN cord-277665-ac8txr3h 289 11 the the DT cord-277665-ac8txr3h 289 12 surface surface NN cord-277665-ac8txr3h 289 13 make make VBP cord-277665-ac8txr3h 289 14 this this DT cord-277665-ac8txr3h 289 15 an an DT cord-277665-ac8txr3h 289 16 interesting interesting JJ cord-277665-ac8txr3h 289 17 approach approach NN cord-277665-ac8txr3h 289 18 for for IN cord-277665-ac8txr3h 289 19 implant implant JJ cord-277665-ac8txr3h 289 20 engineering engineering NN cord-277665-ac8txr3h 289 21 . . . cord-277665-ac8txr3h 290 1 The the DT cord-277665-ac8txr3h 290 2 high high JJ cord-277665-ac8txr3h 290 3 biocompatibility biocompatibility NN cord-277665-ac8txr3h 290 4 , , , cord-277665-ac8txr3h 290 5 corrosion corrosion NN cord-277665-ac8txr3h 290 6 resistance resistance NN cord-277665-ac8txr3h 290 7 , , , cord-277665-ac8txr3h 290 8 chemical chemical NN cord-277665-ac8txr3h 290 9 inertness inertness NN cord-277665-ac8txr3h 290 10 , , , cord-277665-ac8txr3h 290 11 low low JJ cord-277665-ac8txr3h 290 12 friction friction NN cord-277665-ac8txr3h 290 13 coefficient coefficient NN cord-277665-ac8txr3h 290 14 , , , cord-277665-ac8txr3h 290 15 electrical electrical JJ cord-277665-ac8txr3h 290 16 insulation insulation NN cord-277665-ac8txr3h 290 17 , , , cord-277665-ac8txr3h 290 18 and and CC cord-277665-ac8txr3h 290 19 excellent excellent JJ cord-277665-ac8txr3h 290 20 mechanical mechanical JJ cord-277665-ac8txr3h 290 21 characteristics characteristic NNS cord-277665-ac8txr3h 290 22 of of IN cord-277665-ac8txr3h 290 23 CVD CVD NNP cord-277665-ac8txr3h 290 24 diamond diamond NN cord-277665-ac8txr3h 290 25 suggested suggest VBD cord-277665-ac8txr3h 290 26 that that IN cord-277665-ac8txr3h 290 27 diamond diamond NN cord-277665-ac8txr3h 290 28 - - HYPH cord-277665-ac8txr3h 290 29 coated coated JJ cord-277665-ac8txr3h 290 30 materials material NNS cord-277665-ac8txr3h 290 31 may may MD cord-277665-ac8txr3h 290 32 find find VB cord-277665-ac8txr3h 290 33 numerous numerous JJ cord-277665-ac8txr3h 290 34 applications application NNS cord-277665-ac8txr3h 290 35 in in IN cord-277665-ac8txr3h 290 36 medicine medicine NN cord-277665-ac8txr3h 290 37 ( ( -LRB- cord-277665-ac8txr3h 290 38 Tang Tang NNP cord-277665-ac8txr3h 290 39 et et FW cord-277665-ac8txr3h 290 40 al al NNP cord-277665-ac8txr3h 290 41 . . NNP cord-277665-ac8txr3h 290 42 , , , cord-277665-ac8txr3h 290 43 1995 1995 CD cord-277665-ac8txr3h 290 44 ) ) -RRB- cord-277665-ac8txr3h 290 45 . . . cord-277665-ac8txr3h 291 1 In in IN cord-277665-ac8txr3h 291 2 biomaterials biomaterial NNS cord-277665-ac8txr3h 291 3 research research NN cord-277665-ac8txr3h 291 4 , , , cord-277665-ac8txr3h 291 5 it -PRON- PRP cord-277665-ac8txr3h 291 6 is be VBZ cord-277665-ac8txr3h 291 7 known know VBN cord-277665-ac8txr3h 291 8 that that IN cord-277665-ac8txr3h 291 9 the the DT cord-277665-ac8txr3h 291 10 biocompatibility biocompatibility NN cord-277665-ac8txr3h 291 11 of of IN cord-277665-ac8txr3h 291 12 a a DT cord-277665-ac8txr3h 291 13 bulk bulk JJ cord-277665-ac8txr3h 291 14 material material NN cord-277665-ac8txr3h 291 15 is be VBZ cord-277665-ac8txr3h 291 16 not not RB cord-277665-ac8txr3h 291 17 necessarily necessarily RB cord-277665-ac8txr3h 291 18 the the DT cord-277665-ac8txr3h 291 19 same same JJ cord-277665-ac8txr3h 291 20 as as IN cord-277665-ac8txr3h 291 21 the the DT cord-277665-ac8txr3h 291 22 biocompatibility biocompatibility NN cord-277665-ac8txr3h 291 23 of of IN cord-277665-ac8txr3h 291 24 fine fine JJ cord-277665-ac8txr3h 291 25 parti parti JJ cord-277665-ac8txr3h 291 26 - - HYPH cord-277665-ac8txr3h 291 27 cles cles NNP cord-277665-ac8txr3h 291 28 of of IN cord-277665-ac8txr3h 291 29 the the DT cord-277665-ac8txr3h 291 30 same same JJ cord-277665-ac8txr3h 291 31 material material NN cord-277665-ac8txr3h 291 32 , , , cord-277665-ac8txr3h 291 33 which which WDT cord-277665-ac8txr3h 291 34 may may MD cord-277665-ac8txr3h 291 35 penetrate penetrate VB cord-277665-ac8txr3h 291 36 inside inside RB cord-277665-ac8txr3h 291 37 live live JJ cord-277665-ac8txr3h 291 38 cells cell NNS cord-277665-ac8txr3h 291 39 and and CC cord-277665-ac8txr3h 291 40 their -PRON- PRP$ cord-277665-ac8txr3h 291 41 organelles organelle NNS cord-277665-ac8txr3h 291 42 ( ( -LRB- cord-277665-ac8txr3h 291 43 Freitas Freitas NNP cord-277665-ac8txr3h 291 44 , , , cord-277665-ac8txr3h 291 45 2003 2003 CD cord-277665-ac8txr3h 291 46 ) ) -RRB- cord-277665-ac8txr3h 291 47 . . . cord-277665-ac8txr3h 292 1 The the DT cord-277665-ac8txr3h 292 2 main main JJ cord-277665-ac8txr3h 292 3 threat threat NN cord-277665-ac8txr3h 292 4 to to IN cord-277665-ac8txr3h 292 5 cell cell NN cord-277665-ac8txr3h 292 6 viability viability NN cord-277665-ac8txr3h 292 7 comes come VBZ cord-277665-ac8txr3h 292 8 from from IN cord-277665-ac8txr3h 292 9 possible possible JJ cord-277665-ac8txr3h 292 10 mechanical mechanical JJ cord-277665-ac8txr3h 292 11 damage damage NN cord-277665-ac8txr3h 292 12 to to IN cord-277665-ac8txr3h 292 13 cellular cellular JJ cord-277665-ac8txr3h 292 14 organelles organelle NNS cord-277665-ac8txr3h 292 15 and and CC cord-277665-ac8txr3h 292 16 membranes membrane NNS cord-277665-ac8txr3h 292 17 . . . cord-277665-ac8txr3h 293 1 Foreign foreign JJ cord-277665-ac8txr3h 293 2 intracellular intracellular JJ cord-277665-ac8txr3h 293 3 particles particle NNS cord-277665-ac8txr3h 293 4 with with IN cord-277665-ac8txr3h 293 5 a a DT cord-277665-ac8txr3h 293 6 diameter diameter NN cord-277665-ac8txr3h 293 7 of of IN cord-277665-ac8txr3h 293 8 20 20 CD cord-277665-ac8txr3h 293 9 - - SYM cord-277665-ac8txr3h 293 10 200 200 CD cord-277665-ac8txr3h 293 11 nm nm NN cord-277665-ac8txr3h 293 12 do do VBP cord-277665-ac8txr3h 293 13 not not RB cord-277665-ac8txr3h 293 14 damage damage VB cord-277665-ac8txr3h 293 15 cells cell NNS cord-277665-ac8txr3h 293 16 mechanically mechanically RB cord-277665-ac8txr3h 294 1 ( ( -LRB- cord-277665-ac8txr3h 294 2 Lu Lu NNP cord-277665-ac8txr3h 294 3 and and CC cord-277665-ac8txr3h 294 4 Rosenzweig Rosenzweig NNP cord-277665-ac8txr3h 294 5 , , , cord-277665-ac8txr3h 294 6 2000 2000 CD cord-277665-ac8txr3h 294 7 ) ) -RRB- cord-277665-ac8txr3h 294 8 . . . cord-277665-ac8txr3h 295 1 Detonation detonation NN cord-277665-ac8txr3h 295 2 particles particle NNS cord-277665-ac8txr3h 295 3 possess possess VBP cord-277665-ac8txr3h 295 4 a a DT cord-277665-ac8txr3h 295 5 rounded rounded JJ cord-277665-ac8txr3h 295 6 shape shape NN cord-277665-ac8txr3h 295 7 , , , cord-277665-ac8txr3h 295 8 superior superior JJ cord-277665-ac8txr3h 295 9 lubricity lubricity NN cord-277665-ac8txr3h 295 10 characteristics characteristic NNS cord-277665-ac8txr3h 295 11 , , , cord-277665-ac8txr3h 295 12 hardness hardness NN cord-277665-ac8txr3h 295 13 , , , cord-277665-ac8txr3h 295 14 and and CC cord-277665-ac8txr3h 295 15 wear wear VB cord-277665-ac8txr3h 295 16 resistance resistance NN cord-277665-ac8txr3h 295 17 . . . cord-277665-ac8txr3h 296 1 The the DT cord-277665-ac8txr3h 296 2 fine fine JJ cord-277665-ac8txr3h 296 3 diamond diamond NN cord-277665-ac8txr3h 296 4 particles particle NNS cord-277665-ac8txr3h 296 5 and and CC cord-277665-ac8txr3h 296 6 diamond diamond NN cord-277665-ac8txr3h 296 7 - - HYPH cord-277665-ac8txr3h 296 8 like like JJ cord-277665-ac8txr3h 296 9 carbon carbon NN cord-277665-ac8txr3h 296 10 coatings coating NNS cord-277665-ac8txr3h 296 11 were be VBD cord-277665-ac8txr3h 296 12 always always RB cord-277665-ac8txr3h 296 13 found find VBN cord-277665-ac8txr3h 296 14 to to TO cord-277665-ac8txr3h 296 15 be be VB cord-277665-ac8txr3h 296 16 very very RB cord-277665-ac8txr3h 296 17 inert inert JJ cord-277665-ac8txr3h 296 18 and and CC cord-277665-ac8txr3h 296 19 non non JJ cord-277665-ac8txr3h 296 20 - - JJ cord-277665-ac8txr3h 296 21 inflammatory inflammatory JJ cord-277665-ac8txr3h 296 22 ( ( -LRB- cord-277665-ac8txr3h 296 23 Tse Tse NNP cord-277665-ac8txr3h 296 24 and and CC cord-277665-ac8txr3h 296 25 Phelps Phelps NNP cord-277665-ac8txr3h 296 26 , , , cord-277665-ac8txr3h 296 27 1970 1970 CD cord-277665-ac8txr3h 296 28 ; ; : cord-277665-ac8txr3h 296 29 Hedenborg Hedenborg NNP cord-277665-ac8txr3h 296 30 and and CC cord-277665-ac8txr3h 296 31 Klockars Klockars NNP cord-277665-ac8txr3h 296 32 , , , cord-277665-ac8txr3h 296 33 1989 1989 CD cord-277665-ac8txr3h 296 34 ; ; : cord-277665-ac8txr3h 297 1 Swan Swan NNP cord-277665-ac8txr3h 297 2 et et NNP cord-277665-ac8txr3h 297 3 al al NNP cord-277665-ac8txr3h 297 4 . . NNP cord-277665-ac8txr3h 297 5 , , , cord-277665-ac8txr3h 297 6 1990 1990 CD cord-277665-ac8txr3h 297 7 ; ; : cord-277665-ac8txr3h 297 8 Grill Grill NNP cord-277665-ac8txr3h 297 9 , , , cord-277665-ac8txr3h 297 10 2003 2003 CD cord-277665-ac8txr3h 297 11 ) ) -RRB- cord-277665-ac8txr3h 297 12 . . . cord-277665-ac8txr3h 298 1 When when WRB cord-277665-ac8txr3h 298 2 Higson Higson NNP cord-277665-ac8txr3h 298 3 and and CC cord-277665-ac8txr3h 298 4 Jones Jones NNP cord-277665-ac8txr3h 298 5 ( ( -LRB- cord-277665-ac8txr3h 298 6 1984 1984 CD cord-277665-ac8txr3h 298 7 ) ) -RRB- cord-277665-ac8txr3h 298 8 treated treat VBD cord-277665-ac8txr3h 298 9 both both CC cord-277665-ac8txr3h 298 10 pig pig NN cord-277665-ac8txr3h 298 11 and and CC cord-277665-ac8txr3h 298 12 horse horse NN cord-277665-ac8txr3h 298 13 neutrophils neutrophil NNS cord-277665-ac8txr3h 298 14 with with IN cord-277665-ac8txr3h 298 15 diamond diamond NN cord-277665-ac8txr3h 298 16 crystals crystal NNS cord-277665-ac8txr3h 298 17 , , , cord-277665-ac8txr3h 298 18 no no DT cord-277665-ac8txr3h 298 19 induction induction NN cord-277665-ac8txr3h 298 20 of of IN cord-277665-ac8txr3h 298 21 peroxide peroxide NN cord-277665-ac8txr3h 298 22 and and CC cord-277665-ac8txr3h 298 23 superoxide superoxide NN cord-277665-ac8txr3h 298 24 generation generation NN cord-277665-ac8txr3h 298 25 was be VBD cord-277665-ac8txr3h 298 26 observed observe VBN cord-277665-ac8txr3h 298 27 . . . cord-277665-ac8txr3h 299 1 The the DT cord-277665-ac8txr3h 299 2 interaction interaction NN cord-277665-ac8txr3h 299 3 of of IN cord-277665-ac8txr3h 299 4 leucocytes leucocyte NNS cord-277665-ac8txr3h 299 5 with with IN cord-277665-ac8txr3h 299 6 diamonds diamond NNS cord-277665-ac8txr3h 299 7 with with IN cord-277665-ac8txr3h 299 8 a a DT cord-277665-ac8txr3h 299 9 size size NN cord-277665-ac8txr3h 299 10 of of IN cord-277665-ac8txr3h 299 11 4 4 CD cord-277665-ac8txr3h 299 12 - - SYM cord-277665-ac8txr3h 299 13 8 8 CD cord-277665-ac8txr3h 299 14 µm µm NN cord-277665-ac8txr3h 299 15 in in IN cord-277665-ac8txr3h 299 16 0.2 0.2 CD cord-277665-ac8txr3h 299 17 % % NN cord-277665-ac8txr3h 299 18 diamond diamond NN cord-277665-ac8txr3h 299 19 suspension suspension NN cord-277665-ac8txr3h 299 20 did do VBD cord-277665-ac8txr3h 299 21 not not RB cord-277665-ac8txr3h 299 22 cause cause VB cord-277665-ac8txr3h 299 23 any any DT cord-277665-ac8txr3h 299 24 cell cell NN cord-277665-ac8txr3h 299 25 damage damage NN cord-277665-ac8txr3h 299 26 . . . cord-277665-ac8txr3h 300 1 No no DT cord-277665-ac8txr3h 300 2 increase increase NN cord-277665-ac8txr3h 300 3 in in IN cord-277665-ac8txr3h 300 4 degranulation degranulation NN cord-277665-ac8txr3h 300 5 and and CC cord-277665-ac8txr3h 300 6 production production NN cord-277665-ac8txr3h 300 7 of of IN cord-277665-ac8txr3h 300 8 cell cell NN cord-277665-ac8txr3h 300 9 motility motility NN cord-277665-ac8txr3h 300 10 factors factor NNS cord-277665-ac8txr3h 300 11 , , , cord-277665-ac8txr3h 300 12 and and CC cord-277665-ac8txr3h 300 13 cell cell NN cord-277665-ac8txr3h 300 14 death death NN cord-277665-ac8txr3h 300 15 , , , cord-277665-ac8txr3h 300 16 was be VBD cord-277665-ac8txr3h 300 17 observed observe VBN cord-277665-ac8txr3h 300 18 ( ( -LRB- cord-277665-ac8txr3h 301 1 Swan Swan NNP cord-277665-ac8txr3h 301 2 et et NNP cord-277665-ac8txr3h 301 3 al al NNP cord-277665-ac8txr3h 301 4 . . NNP cord-277665-ac8txr3h 301 5 , , , cord-277665-ac8txr3h 301 6 1990 1990 CD cord-277665-ac8txr3h 301 7 ) ) -RRB- cord-277665-ac8txr3h 301 8 . . . cord-277665-ac8txr3h 302 1 compared compare VBN cord-277665-ac8txr3h 302 2 particles particle NNS cord-277665-ac8txr3h 302 3 of of IN cord-277665-ac8txr3h 302 4 diamond diamond NN cord-277665-ac8txr3h 302 5 , , , cord-277665-ac8txr3h 302 6 SiC sic NN cord-277665-ac8txr3h 302 7 , , , cord-277665-ac8txr3h 302 8 and and CC cord-277665-ac8txr3h 302 9 hydroxyapatite hydroxyapatite NN cord-277665-ac8txr3h 302 10 in in IN cord-277665-ac8txr3h 302 11 serum serum NN cord-277665-ac8txr3h 302 12 - - HYPH cord-277665-ac8txr3h 302 13 free free JJ cord-277665-ac8txr3h 302 14 cultures culture NNS cord-277665-ac8txr3h 302 15 of of IN cord-277665-ac8txr3h 302 16 human human JJ cord-277665-ac8txr3h 302 17 monocytes monocyte NNS cord-277665-ac8txr3h 302 18 and and CC cord-277665-ac8txr3h 302 19 found find VBD cord-277665-ac8txr3h 302 20 that that IN cord-277665-ac8txr3h 302 21 all all DT cord-277665-ac8txr3h 302 22 particles particle NNS cord-277665-ac8txr3h 302 23 were be VBD cord-277665-ac8txr3h 302 24 phagocytozed phagocytoze VBN cord-277665-ac8txr3h 302 25 , , , cord-277665-ac8txr3h 302 26 and and CC cord-277665-ac8txr3h 302 27 monocyte monocyte NNP cord-277665-ac8txr3h 302 28 morphology morphology NN cord-277665-ac8txr3h 302 29 changed change VBD cord-277665-ac8txr3h 302 30 except except IN cord-277665-ac8txr3h 302 31 after after IN cord-277665-ac8txr3h 302 32 the the DT cord-277665-ac8txr3h 302 33 ingestion ingestion NN cord-277665-ac8txr3h 302 34 of of IN cord-277665-ac8txr3h 302 35 diamond diamond NN cord-277665-ac8txr3h 302 36 . . . cord-277665-ac8txr3h 303 1 It -PRON- PRP cord-277665-ac8txr3h 303 2 was be VBD cord-277665-ac8txr3h 303 3 concluded conclude VBN cord-277665-ac8txr3h 303 4 that that IN cord-277665-ac8txr3h 303 5 diamond diamond NN cord-277665-ac8txr3h 303 6 particles particle NNS cord-277665-ac8txr3h 303 7 were be VBD cord-277665-ac8txr3h 303 8 inert inert JJ cord-277665-ac8txr3h 303 9 in in IN cord-277665-ac8txr3h 303 10 a a DT cord-277665-ac8txr3h 303 11 serum serum NN cord-277665-ac8txr3h 303 12 - - HYPH cord-277665-ac8txr3h 303 13 free free JJ cord-277665-ac8txr3h 303 14 human human JJ cord-277665-ac8txr3h 303 15 monocyte monocyte NNP cord-277665-ac8txr3h 303 16 culture culture NN cord-277665-ac8txr3h 303 17 , , , cord-277665-ac8txr3h 303 18 while while IN cord-277665-ac8txr3h 303 19 both both DT cord-277665-ac8txr3h 303 20 SiC sic NN cord-277665-ac8txr3h 303 21 and and CC cord-277665-ac8txr3h 303 22 hydroxyapatite hydroxyapatite NN cord-277665-ac8txr3h 303 23 had have VBD cord-277665-ac8txr3h 303 24 a a DT cord-277665-ac8txr3h 303 25 stimulatory stimulatory JJ cord-277665-ac8txr3h 303 26 effect effect NN cord-277665-ac8txr3h 303 27 comparable comparable JJ cord-277665-ac8txr3h 303 28 to to IN cord-277665-ac8txr3h 303 29 that that DT cord-277665-ac8txr3h 303 30 of of IN cord-277665-ac8txr3h 303 31 polymethylmethacrylate polymethylmethacrylate NNP cord-277665-ac8txr3h 303 32 . . . cord-277665-ac8txr3h 304 1 When when WRB cord-277665-ac8txr3h 304 2 suspensions suspension NNS cord-277665-ac8txr3h 304 3 of of IN cord-277665-ac8txr3h 304 4 phagocytosable phagocytosable JJ cord-277665-ac8txr3h 304 5 particles particle NNS cord-277665-ac8txr3h 304 6 of of IN cord-277665-ac8txr3h 304 7 diamond diamond NN cord-277665-ac8txr3h 304 8 and and CC cord-277665-ac8txr3h 304 9 SiC sic NN cord-277665-ac8txr3h 304 10 in in IN cord-277665-ac8txr3h 304 11 hyaluronan hyaluronan NNP cord-277665-ac8txr3h 304 12 were be VBD cord-277665-ac8txr3h 304 13 introduced introduce VBN cord-277665-ac8txr3h 304 14 into into IN cord-277665-ac8txr3h 304 15 a a DT cord-277665-ac8txr3h 304 16 canal canal NN cord-277665-ac8txr3h 304 17 traversing traverse VBG cord-277665-ac8txr3h 304 18 the the DT cord-277665-ac8txr3h 304 19 bone bone NN cord-277665-ac8txr3h 304 20 implant implant NN cord-277665-ac8txr3h 304 21 in in IN cord-277665-ac8txr3h 304 22 rabbits rabbit NNS cord-277665-ac8txr3h 304 23 neither neither CC cord-277665-ac8txr3h 304 24 the the DT cord-277665-ac8txr3h 304 25 diamond diamond NN cord-277665-ac8txr3h 304 26 nor nor CC cord-277665-ac8txr3h 304 27 the the DT cord-277665-ac8txr3h 304 28 SiC sic NN cord-277665-ac8txr3h 304 29 particles particle NNS cord-277665-ac8txr3h 304 30 caused cause VBD cord-277665-ac8txr3h 304 31 any any DT cord-277665-ac8txr3h 304 32 decrease decrease NN cord-277665-ac8txr3h 304 33 in in IN cord-277665-ac8txr3h 304 34 bone bone NN cord-277665-ac8txr3h 304 35 formation formation NN cord-277665-ac8txr3h 304 36 . . . cord-277665-ac8txr3h 305 1 It -PRON- PRP cord-277665-ac8txr3h 305 2 confirmed confirm VBD cord-277665-ac8txr3h 305 3 that that IN cord-277665-ac8txr3h 305 4 particles particle NNS cord-277665-ac8txr3h 305 5 of of IN cord-277665-ac8txr3h 305 6 diamond diamond NN cord-277665-ac8txr3h 305 7 and and CC cord-277665-ac8txr3h 305 8 SiC sic NN cord-277665-ac8txr3h 305 9 are be VBP cord-277665-ac8txr3h 305 10 harmless harmless JJ cord-277665-ac8txr3h 305 11 . . . cord-277665-ac8txr3h 306 1 Human human JJ cord-277665-ac8txr3h 306 2 blood blood NN cord-277665-ac8txr3h 306 3 cells cell NNS cord-277665-ac8txr3h 306 4 ' ' POS cord-277665-ac8txr3h 306 5 lack lack NN cord-277665-ac8txr3h 306 6 of of IN cord-277665-ac8txr3h 306 7 adherence adherence NN cord-277665-ac8txr3h 306 8 to to IN cord-277665-ac8txr3h 306 9 the the DT cord-277665-ac8txr3h 306 10 CVD CVD NNP cord-277665-ac8txr3h 306 11 diamond diamond NN cord-277665-ac8txr3h 306 12 substrates substrate NNS cord-277665-ac8txr3h 306 13 , , , cord-277665-ac8txr3h 306 14 and and CC cord-277665-ac8txr3h 306 15 blood blood NN cord-277665-ac8txr3h 306 16 clotting clotting NN cord-277665-ac8txr3h 306 17 on on IN cord-277665-ac8txr3h 306 18 diamond diamond NN cord-277665-ac8txr3h 306 19 , , , cord-277665-ac8txr3h 306 20 produced produce VBD cord-277665-ac8txr3h 306 21 a a DT cord-277665-ac8txr3h 306 22 less less RBR cord-277665-ac8txr3h 306 23 rough rough JJ cord-277665-ac8txr3h 306 24 surface surface NN cord-277665-ac8txr3h 306 25 than than IN cord-277665-ac8txr3h 306 26 blood blood NN cord-277665-ac8txr3h 306 27 clotting clotting NN cord-277665-ac8txr3h 306 28 on on IN cord-277665-ac8txr3h 306 29 glass glass NN cord-277665-ac8txr3h 306 30 ( ( -LRB- cord-277665-ac8txr3h 306 31 Baranauskas Baranauskas NNP cord-277665-ac8txr3h 306 32 et et NNP cord-277665-ac8txr3h 306 33 al al NNP cord-277665-ac8txr3h 306 34 . . NNP cord-277665-ac8txr3h 306 35 , , , cord-277665-ac8txr3h 306 36 2004 2004 CD cord-277665-ac8txr3h 306 37 ) ) -RRB- cord-277665-ac8txr3h 306 38 . . . cord-277665-ac8txr3h 307 1 Recent recent JJ cord-277665-ac8txr3h 307 2 reports report NNS cord-277665-ac8txr3h 307 3 on on IN cord-277665-ac8txr3h 307 4 possible possible JJ cord-277665-ac8txr3h 307 5 ND ND NNP cord-277665-ac8txr3h 307 6 - - HYPH cord-277665-ac8txr3h 307 7 induced induce VBN cord-277665-ac8txr3h 307 8 damage damage NN cord-277665-ac8txr3h 307 9 to to IN cord-277665-ac8txr3h 307 10 both both CC cord-277665-ac8txr3h 307 11 white white JJ cord-277665-ac8txr3h 307 12 and and CC cord-277665-ac8txr3h 307 13 red red JJ cord-277665-ac8txr3h 307 14 human human JJ cord-277665-ac8txr3h 307 15 blood blood NN cord-277665-ac8txr3h 307 16 cells cell NNS cord-277665-ac8txr3h 307 17 in in IN cord-277665-ac8txr3h 307 18 vitro vitro FW cord-277665-ac8txr3h 307 19 ( ( -LRB- cord-277665-ac8txr3h 307 20 Puzyr Puzyr NNP cord-277665-ac8txr3h 307 21 et et NNP cord-277665-ac8txr3h 307 22 al al NNP cord-277665-ac8txr3h 307 23 . . NNP cord-277665-ac8txr3h 307 24 , , , cord-277665-ac8txr3h 307 25 2002 2002 CD cord-277665-ac8txr3h 307 26 ; ; : cord-277665-ac8txr3h 307 27 2004b 2004b CD cord-277665-ac8txr3h 307 28 ; ; , cord-277665-ac8txr3h 307 29 raised raise VBD cord-277665-ac8txr3h 307 30 the the DT cord-277665-ac8txr3h 307 31 question question NN cord-277665-ac8txr3h 307 32 about about IN cord-277665-ac8txr3h 307 33 the the DT cord-277665-ac8txr3h 307 34 mechanism mechanism NN cord-277665-ac8txr3h 307 35 promoting promote VBG cord-277665-ac8txr3h 307 36 these these DT cord-277665-ac8txr3h 307 37 phenomena phenomenon NNS cord-277665-ac8txr3h 307 38 . . . cord-277665-ac8txr3h 308 1 Prior prior RB cord-277665-ac8txr3h 308 2 to to TO cord-277665-ac8txr3h 308 3 use use VB cord-277665-ac8txr3h 308 4 , , , cord-277665-ac8txr3h 308 5 NDs nd NNS cord-277665-ac8txr3h 308 6 are be VBP cord-277665-ac8txr3h 308 7 usually usually RB cord-277665-ac8txr3h 308 8 modified modify VBN cord-277665-ac8txr3h 308 9 to to TO cord-277665-ac8txr3h 308 10 gain gain VB cord-277665-ac8txr3h 308 11 high high JJ cord-277665-ac8txr3h 308 12 stability stability NN cord-277665-ac8txr3h 308 13 in in IN cord-277665-ac8txr3h 308 14 water water NN cord-277665-ac8txr3h 308 15 colloids colloid NNS cord-277665-ac8txr3h 308 16 , , , cord-277665-ac8txr3h 308 17 and and CC cord-277665-ac8txr3h 308 18 it -PRON- PRP cord-277665-ac8txr3h 308 19 is be VBZ cord-277665-ac8txr3h 308 20 not not RB cord-277665-ac8txr3h 308 21 clear clear JJ cord-277665-ac8txr3h 308 22 whether whether IN cord-277665-ac8txr3h 308 23 bacterial bacterial JJ cord-277665-ac8txr3h 308 24 contamination contamination NN cord-277665-ac8txr3h 308 25 , , , cord-277665-ac8txr3h 308 26 unidentified unidentified JJ cord-277665-ac8txr3h 308 27 impurities impurity NNS cord-277665-ac8txr3h 308 28 , , , cord-277665-ac8txr3h 308 29 defects defect NNS cord-277665-ac8txr3h 308 30 ( ( -LRB- cord-277665-ac8txr3h 308 31 Shames shame VBZ cord-277665-ac8txr3h 308 32 et et NNP cord-277665-ac8txr3h 308 33 al al NNP cord-277665-ac8txr3h 308 34 . . NNP cord-277665-ac8txr3h 308 35 , , , cord-277665-ac8txr3h 308 36 2002 2002 CD cord-277665-ac8txr3h 308 37 ) ) -RRB- cord-277665-ac8txr3h 308 38 , , , cord-277665-ac8txr3h 308 39 and and CC cord-277665-ac8txr3h 308 40 surfactants surfactant NNS cord-277665-ac8txr3h 308 41 were be VBD cord-277665-ac8txr3h 308 42 not not RB cord-277665-ac8txr3h 308 43 the the DT cord-277665-ac8txr3h 308 44 factors factor NNS cord-277665-ac8txr3h 308 45 involved involve VBN cord-277665-ac8txr3h 308 46 . . . cord-277665-ac8txr3h 309 1 Indeed indeed RB cord-277665-ac8txr3h 309 2 , , , cord-277665-ac8txr3h 309 3 in in IN cord-277665-ac8txr3h 309 4 those those DT cord-277665-ac8txr3h 309 5 studies study NNS cord-277665-ac8txr3h 309 6 , , , cord-277665-ac8txr3h 309 7 the the DT cord-277665-ac8txr3h 309 8 total total JJ cord-277665-ac8txr3h 309 9 content content NN cord-277665-ac8txr3h 309 10 of of IN cord-277665-ac8txr3h 309 11 nondiamond nondiamond NN cord-277665-ac8txr3h 309 12 carbon carbon NN cord-277665-ac8txr3h 309 13 , , , cord-277665-ac8txr3h 309 14 non non JJ cord-277665-ac8txr3h 309 15 - - JJ cord-277665-ac8txr3h 309 16 combustible combustible JJ cord-277665-ac8txr3h 309 17 residue residue NN cord-277665-ac8txr3h 309 18 , , , cord-277665-ac8txr3h 309 19 and and CC cord-277665-ac8txr3h 309 20 volatile volatile JJ cord-277665-ac8txr3h 309 21 compounds compound NNS cord-277665-ac8txr3h 309 22 reached reach VBD cord-277665-ac8txr3h 309 23 16 16 CD cord-277665-ac8txr3h 309 24 % % NN cord-277665-ac8txr3h 309 25 in in IN cord-277665-ac8txr3h 309 26 some some DT cord-277665-ac8txr3h 309 27 samples sample NNS cord-277665-ac8txr3h 309 28 ( ( -LRB- cord-277665-ac8txr3h 309 29 Puzyr Puzyr NNP cord-277665-ac8txr3h 309 30 et et NNP cord-277665-ac8txr3h 309 31 al al NNP cord-277665-ac8txr3h 309 32 . . NNP cord-277665-ac8txr3h 309 33 , , , cord-277665-ac8txr3h 309 34 2002 2002 CD cord-277665-ac8txr3h 309 35 ) ) -RRB- cord-277665-ac8txr3h 309 36 . . . cord-277665-ac8txr3h 310 1 In in IN cord-277665-ac8txr3h 310 2 contrast contrast NN cord-277665-ac8txr3h 310 3 to to IN cord-277665-ac8txr3h 310 4 these these DT cord-277665-ac8txr3h 310 5 observations observation NNS cord-277665-ac8txr3h 310 6 , , , cord-277665-ac8txr3h 310 7 Dion Dion NNP cord-277665-ac8txr3h 310 8 et et NNP cord-277665-ac8txr3h 310 9 al al NNP cord-277665-ac8txr3h 310 10 . . . cord-277665-ac8txr3h 311 1 ( ( -LRB- cord-277665-ac8txr3h 311 2 1993 1993 CD cord-277665-ac8txr3h 311 3 ) ) -RRB- cord-277665-ac8txr3h 311 4 did do VBD cord-277665-ac8txr3h 311 5 not not RB cord-277665-ac8txr3h 311 6 notice notice VB cord-277665-ac8txr3h 311 7 any any DT cord-277665-ac8txr3h 311 8 in in FW cord-277665-ac8txr3h 311 9 vitro vitro FW cord-277665-ac8txr3h 311 10 hemolysis hemolysis NN cord-277665-ac8txr3h 311 11 when when WRB cord-277665-ac8txr3h 311 12 14 14 CD cord-277665-ac8txr3h 311 13 % % NN cord-277665-ac8txr3h 311 14 blood blood NN cord-277665-ac8txr3h 311 15 solutions solution NNS cord-277665-ac8txr3h 311 16 were be VBD cord-277665-ac8txr3h 311 17 treated treat VBN cord-277665-ac8txr3h 311 18 with with IN cord-277665-ac8txr3h 311 19 0.5 0.5 CD cord-277665-ac8txr3h 311 20 g g NN cord-277665-ac8txr3h 311 21 cm cm NN cord-277665-ac8txr3h 311 22 −3 −3 NNP cord-277665-ac8txr3h 311 23 diamond diamond NN cord-277665-ac8txr3h 311 24 powder powder NN cord-277665-ac8txr3h 311 25 produced produce VBN cord-277665-ac8txr3h 311 26 by by IN cord-277665-ac8txr3h 311 27 De De NNP cord-277665-ac8txr3h 311 28 Beers Beers NNP cord-277665-ac8txr3h 311 29 Industrial Industrial NNP cord-277665-ac8txr3h 311 30 Diamond Diamond NNP cord-277665-ac8txr3h 311 31 Division Division NNP cord-277665-ac8txr3h 311 32 , , , cord-277665-ac8txr3h 311 33 and and CC cord-277665-ac8txr3h 311 34 the the DT cord-277665-ac8txr3h 311 35 early early JJ cord-277665-ac8txr3h 311 36 reports report NNS cord-277665-ac8txr3h 311 37 on on IN cord-277665-ac8txr3h 311 38 crystalline crystalline JJ cord-277665-ac8txr3h 311 39 diamond diamond NN cord-277665-ac8txr3h 311 40 - - HYPH cord-277665-ac8txr3h 311 41 induced induce VBN cord-277665-ac8txr3h 311 42 damage damage NN cord-277665-ac8txr3h 311 43 to to IN cord-277665-ac8txr3h 311 44 cells cell NNS cord-277665-ac8txr3h 311 45 were be VBD cord-277665-ac8txr3h 311 46 never never RB cord-277665-ac8txr3h 311 47 confirmed confirm VBN cord-277665-ac8txr3h 311 48 ( ( -LRB- cord-277665-ac8txr3h 311 49 Freitas Freitas NNP cord-277665-ac8txr3h 311 50 , , , cord-277665-ac8txr3h 311 51 2003 2003 CD cord-277665-ac8txr3h 311 52 ) ) -RRB- cord-277665-ac8txr3h 311 53 . . . cord-277665-ac8txr3h 312 1 Rodil Rodil NNP cord-277665-ac8txr3h 312 2 et et NNP cord-277665-ac8txr3h 312 3 al al NNP cord-277665-ac8txr3h 312 4 . . . cord-277665-ac8txr3h 313 1 ( ( -LRB- cord-277665-ac8txr3h 313 2 2005 2005 CD cord-277665-ac8txr3h 313 3 ) ) -RRB- cord-277665-ac8txr3h 313 4 reported report VBD cord-277665-ac8txr3h 313 5 that that IN cord-277665-ac8txr3h 313 6 the the DT cord-277665-ac8txr3h 313 7 diamond diamond NN cord-277665-ac8txr3h 313 8 - - HYPH cord-277665-ac8txr3h 313 9 like like JJ cord-277665-ac8txr3h 313 10 coating coating NN cord-277665-ac8txr3h 313 11 did do VBD cord-277665-ac8txr3h 313 12 not not RB cord-277665-ac8txr3h 313 13 have have VB cord-277665-ac8txr3h 313 14 any any DT cord-277665-ac8txr3h 313 15 toxic toxic JJ cord-277665-ac8txr3h 313 16 effect effect NN cord-277665-ac8txr3h 313 17 on on IN cord-277665-ac8txr3h 313 18 human human JJ cord-277665-ac8txr3h 313 19 osteoblasts osteoblast NNS cord-277665-ac8txr3h 313 20 cells cell NNS cord-277665-ac8txr3h 313 21 in in IN cord-277665-ac8txr3h 313 22 vitro vitro FW cord-277665-ac8txr3h 313 23 . . . cord-277665-ac8txr3h 314 1 Interestingly interestingly RB cord-277665-ac8txr3h 314 2 , , , cord-277665-ac8txr3h 314 3 Monteiro Monteiro NNP cord-277665-ac8txr3h 314 4 - - HYPH cord-277665-ac8txr3h 314 5 Riviere Riviere NNP cord-277665-ac8txr3h 314 6 et et FW cord-277665-ac8txr3h 314 7 al al NNP cord-277665-ac8txr3h 314 8 . . . cord-277665-ac8txr3h 315 1 ( ( -LRB- cord-277665-ac8txr3h 315 2 2005 2005 CD cord-277665-ac8txr3h 315 3 ) ) -RRB- cord-277665-ac8txr3h 315 4 found find VBD cord-277665-ac8txr3h 315 5 that that IN cord-277665-ac8txr3h 315 6 carbon carbon NN cord-277665-ac8txr3h 315 7 nanotubes nanotube NNS cord-277665-ac8txr3h 315 8 , , , cord-277665-ac8txr3h 315 9 which which WDT cord-277665-ac8txr3h 315 10 were be VBD cord-277665-ac8txr3h 315 11 grown grow VBN cord-277665-ac8txr3h 315 12 using use VBG cord-277665-ac8txr3h 315 13 a a DT cord-277665-ac8txr3h 315 14 microwave microwave NN cord-277665-ac8txr3h 315 15 plasma plasma NN cord-277665-ac8txr3h 315 16 enhanced enhance VBN cord-277665-ac8txr3h 315 17 CVD CVD NNP cord-277665-ac8txr3h 315 18 system system NN cord-277665-ac8txr3h 315 19 , , , cord-277665-ac8txr3h 315 20 accumulated accumulate VBN cord-277665-ac8txr3h 315 21 within within IN cord-277665-ac8txr3h 315 22 cytoplasmic cytoplasmic JJ cord-277665-ac8txr3h 315 23 vacuoles vacuole NNS cord-277665-ac8txr3h 315 24 of of IN cord-277665-ac8txr3h 315 25 the the DT cord-277665-ac8txr3h 315 26 human human JJ cord-277665-ac8txr3h 315 27 epidermal epidermal JJ cord-277665-ac8txr3h 315 28 keratinocytes keratinocyte NNS cord-277665-ac8txr3h 315 29 and and CC cord-277665-ac8txr3h 315 30 stimulated stimulate VBD cord-277665-ac8txr3h 315 31 release release NN cord-277665-ac8txr3h 315 32 of of IN cord-277665-ac8txr3h 315 33 the the DT cord-277665-ac8txr3h 315 34 proinflammatory proinflammatory JJ cord-277665-ac8txr3h 315 35 cytokine cytokine NN cord-277665-ac8txr3h 315 36 interleukin interleukin NN cord-277665-ac8txr3h 315 37 8 8 CD cord-277665-ac8txr3h 315 38 . . . cord-277665-ac8txr3h 316 1 There there EX cord-277665-ac8txr3h 316 2 are be VBP cord-277665-ac8txr3h 316 3 no no DT cord-277665-ac8txr3h 316 4 reports report NNS cord-277665-ac8txr3h 316 5 on on IN cord-277665-ac8txr3h 316 6 site site NN cord-277665-ac8txr3h 316 7 - - HYPH cord-277665-ac8txr3h 316 8 specific specific JJ cord-277665-ac8txr3h 316 9 intracellular intracellular JJ cord-277665-ac8txr3h 316 10 accumulation accumulation NN cord-277665-ac8txr3h 316 11 of of IN cord-277665-ac8txr3h 316 12 ND ND NNP cord-277665-ac8txr3h 316 13 particles particle NNS cord-277665-ac8txr3h 316 14 by by IN cord-277665-ac8txr3h 316 15 live live JJ cord-277665-ac8txr3h 316 16 cells cell NNS cord-277665-ac8txr3h 316 17 . . . cord-277665-ac8txr3h 317 1 As as IN cord-277665-ac8txr3h 317 2 was be VBD cord-277665-ac8txr3h 317 3 mentioned mention VBN cord-277665-ac8txr3h 317 4 in in IN cord-277665-ac8txr3h 317 5 the the DT cord-277665-ac8txr3h 317 6 previous previous JJ cord-277665-ac8txr3h 317 7 section section NN cord-277665-ac8txr3h 317 8 , , , cord-277665-ac8txr3h 317 9 administration administration NN cord-277665-ac8txr3h 317 10 of of IN cord-277665-ac8txr3h 317 11 detonation detonation NN cord-277665-ac8txr3h 317 12 ND ND NNP cord-277665-ac8txr3h 317 13 particles particle NNS cord-277665-ac8txr3h 317 14 to to IN cord-277665-ac8txr3h 317 15 both both DT cord-277665-ac8txr3h 317 16 Erlich Erlich NNP cord-277665-ac8txr3h 317 17 ascetic ascetic JJ cord-277665-ac8txr3h 317 18 carcinoma carcinoma NN cord-277665-ac8txr3h 317 19 mice mouse NNS cord-277665-ac8txr3h 317 20 and and CC cord-277665-ac8txr3h 317 21 terminally terminally RB cord-277665-ac8txr3h 317 22 ill ill JJ cord-277665-ac8txr3h 317 23 cancer cancer NN cord-277665-ac8txr3h 317 24 patients patient NNS cord-277665-ac8txr3h 317 25 did do VBD cord-277665-ac8txr3h 317 26 not not RB cord-277665-ac8txr3h 317 27 result result VB cord-277665-ac8txr3h 317 28 in in IN cord-277665-ac8txr3h 317 29 any any DT cord-277665-ac8txr3h 317 30 side side NN cord-277665-ac8txr3h 317 31 effects effect NNS cord-277665-ac8txr3h 317 32 . . . cord-277665-ac8txr3h 318 1 Moreover moreover RB cord-277665-ac8txr3h 318 2 , , , cord-277665-ac8txr3h 318 3 it -PRON- PRP cord-277665-ac8txr3h 318 4 was be VBD cord-277665-ac8txr3h 318 5 beneficial beneficial JJ cord-277665-ac8txr3h 318 6 in in IN cord-277665-ac8txr3h 318 7 some some DT cord-277665-ac8txr3h 318 8 cases case NNS cord-277665-ac8txr3h 318 9 ( ( -LRB- cord-277665-ac8txr3h 318 10 Dolmatov Dolmatov NNP cord-277665-ac8txr3h 318 11 and and CC cord-277665-ac8txr3h 318 12 Kostrova Kostrova NNP cord-277665-ac8txr3h 318 13 , , , cord-277665-ac8txr3h 318 14 2000 2000 CD cord-277665-ac8txr3h 318 15 ; ; : cord-277665-ac8txr3h 318 16 Dolmatov Dolmatov NNP cord-277665-ac8txr3h 318 17 , , , cord-277665-ac8txr3h 318 18 2001 2001 CD cord-277665-ac8txr3h 318 19 ) ) -RRB- cord-277665-ac8txr3h 318 20 . . . cord-277665-ac8txr3h 319 1 However however RB cord-277665-ac8txr3h 319 2 , , , cord-277665-ac8txr3h 319 3 0.002 0.002 CD cord-277665-ac8txr3h 319 4 - - HYPH cord-277665-ac8txr3h 319 5 0.01 0.01 CD cord-277665-ac8txr3h 319 6 % % NN cord-277665-ac8txr3h 319 7 ND ND NNP cord-277665-ac8txr3h 319 8 suspensions suspension NNS cord-277665-ac8txr3h 319 9 administered administer VBN cord-277665-ac8txr3h 319 10 orally orally RB cord-277665-ac8txr3h 319 11 to to IN cord-277665-ac8txr3h 319 12 white white JJ cord-277665-ac8txr3h 319 13 mice mouse NNS cord-277665-ac8txr3h 319 14 over over IN cord-277665-ac8txr3h 319 15 the the DT cord-277665-ac8txr3h 319 16 course course NN cord-277665-ac8txr3h 319 17 of of IN cord-277665-ac8txr3h 319 18 3 3 CD cord-277665-ac8txr3h 319 19 months month NNS cord-277665-ac8txr3h 319 20 did do VBD cord-277665-ac8txr3h 319 21 cause cause VB cord-277665-ac8txr3h 319 22 a a DT cord-277665-ac8txr3h 319 23 substantial substantial JJ cord-277665-ac8txr3h 319 24 increase increase NN cord-277665-ac8txr3h 319 25 in in IN cord-277665-ac8txr3h 319 26 leukocyte leukocyte NN cord-277665-ac8txr3h 319 27 content content NN cord-277665-ac8txr3h 319 28 in in IN cord-277665-ac8txr3h 319 29 the the DT cord-277665-ac8txr3h 319 30 blood blood NN cord-277665-ac8txr3h 319 31 of of IN cord-277665-ac8txr3h 319 32 animals animal NNS cord-277665-ac8txr3h 319 33 ( ( -LRB- cord-277665-ac8txr3h 319 34 Puzyr Puzyr NNP cord-277665-ac8txr3h 319 35 et et NNP cord-277665-ac8txr3h 319 36 al al NNP cord-277665-ac8txr3h 319 37 . . NNP cord-277665-ac8txr3h 319 38 , , , cord-277665-ac8txr3h 319 39 2004c 2004c CD cord-277665-ac8txr3h 319 40 ) ) -RRB- cord-277665-ac8txr3h 319 41 . . . cord-277665-ac8txr3h 320 1 The the DT cord-277665-ac8txr3h 320 2 treatment treatment NN cord-277665-ac8txr3h 320 3 did do VBD cord-277665-ac8txr3h 320 4 not not RB cord-277665-ac8txr3h 320 5 affect affect VB cord-277665-ac8txr3h 320 6 the the DT cord-277665-ac8txr3h 320 7 weight weight NN cord-277665-ac8txr3h 320 8 of of IN cord-277665-ac8txr3h 320 9 the the DT cord-277665-ac8txr3h 320 10 experimental experimental JJ cord-277665-ac8txr3h 320 11 mice mouse NNS cord-277665-ac8txr3h 320 12 though though RB cord-277665-ac8txr3h 320 13 . . . cord-277665-ac8txr3h 321 1 Very very RB cord-277665-ac8txr3h 321 2 unexpectedly unexpectedly RB cord-277665-ac8txr3h 321 3 , , , cord-277665-ac8txr3h 321 4 the the DT cord-277665-ac8txr3h 321 5 intravenous intravenous JJ cord-277665-ac8txr3h 321 6 administration administration NN cord-277665-ac8txr3h 321 7 of of IN cord-277665-ac8txr3h 321 8 0.3 0.3 CD cord-277665-ac8txr3h 321 9 mL ml NN cord-277665-ac8txr3h 321 10 of of IN cord-277665-ac8txr3h 321 11 sterile sterile JJ cord-277665-ac8txr3h 321 12 colloids colloid NNS cord-277665-ac8txr3h 321 13 of of IN cord-277665-ac8txr3h 321 14 1 1 CD cord-277665-ac8txr3h 321 15 % % NN cord-277665-ac8txr3h 321 16 modified modify VBN cord-277665-ac8txr3h 321 17 NDs nd NNS cord-277665-ac8txr3h 321 18 in in IN cord-277665-ac8txr3h 321 19 10 10 CD cord-277665-ac8txr3h 321 20 % % NN cord-277665-ac8txr3h 321 21 glucose glucose NN cord-277665-ac8txr3h 321 22 to to IN cord-277665-ac8txr3h 321 23 rats rat NNS cord-277665-ac8txr3h 321 24 and and CC cord-277665-ac8txr3h 321 25 dogs dog NNS cord-277665-ac8txr3h 321 26 did do VBD cord-277665-ac8txr3h 321 27 not not RB cord-277665-ac8txr3h 321 28 result result VB cord-277665-ac8txr3h 321 29 in in IN cord-277665-ac8txr3h 321 30 sickness sickness NN cord-277665-ac8txr3h 321 31 or or CC cord-277665-ac8txr3h 321 32 premature premature JJ cord-277665-ac8txr3h 321 33 death death NN cord-277665-ac8txr3h 321 34 of of IN cord-277665-ac8txr3h 321 35 the the DT cord-277665-ac8txr3h 321 36 animals animal NNS cord-277665-ac8txr3h 322 1 ( ( -LRB- cord-277665-ac8txr3h 322 2 Puzyr Puzyr NNP cord-277665-ac8txr3h 322 3 et et NNP cord-277665-ac8txr3h 322 4 al al NNP cord-277665-ac8txr3h 322 5 . . NNP cord-277665-ac8txr3h 322 6 , , , cord-277665-ac8txr3h 322 7 2005b 2005b CD cord-277665-ac8txr3h 322 8 ) ) -RRB- cord-277665-ac8txr3h 322 9 . . . cord-277665-ac8txr3h 323 1 When when WRB cord-277665-ac8txr3h 323 2 1 1 CD cord-277665-ac8txr3h 323 3 mL ml NN cord-277665-ac8txr3h 323 4 of of IN cord-277665-ac8txr3h 323 5 1 1 CD cord-277665-ac8txr3h 323 6 % % NN cord-277665-ac8txr3h 323 7 ND ND NNP cord-277665-ac8txr3h 323 8 was be VBD cord-277665-ac8txr3h 323 9 administered administer VBN cord-277665-ac8txr3h 323 10 to to IN cord-277665-ac8txr3h 323 11 a a DT cord-277665-ac8txr3h 323 12 dog dog NN cord-277665-ac8txr3h 323 13 followed follow VBN cord-277665-ac8txr3h 323 14 by by IN cord-277665-ac8txr3h 323 15 the the DT cord-277665-ac8txr3h 323 16 second second JJ cord-277665-ac8txr3h 323 17 administration administration NN cord-277665-ac8txr3h 323 18 1 1 CD cord-277665-ac8txr3h 323 19 week week NN cord-277665-ac8txr3h 323 20 later later RB cord-277665-ac8txr3h 323 21 , , , cord-277665-ac8txr3h 323 22 the the DT cord-277665-ac8txr3h 323 23 ECG ECG NNP cord-277665-ac8txr3h 323 24 tests test NNS cord-277665-ac8txr3h 323 25 revealed reveal VBD cord-277665-ac8txr3h 323 26 substantial substantial JJ cord-277665-ac8txr3h 323 27 changes change NNS cord-277665-ac8txr3h 323 28 in in IN cord-277665-ac8txr3h 323 29 heart heart NN cord-277665-ac8txr3h 323 30 activity activity NN cord-277665-ac8txr3h 323 31 immediately immediately RB cord-277665-ac8txr3h 323 32 after after IN cord-277665-ac8txr3h 323 33 each each DT cord-277665-ac8txr3h 323 34 treatment treatment NN cord-277665-ac8txr3h 323 35 . . . cord-277665-ac8txr3h 324 1 However however RB cord-277665-ac8txr3h 324 2 , , , cord-277665-ac8txr3h 324 3 the the DT cord-277665-ac8txr3h 324 4 cardiac cardiac JJ cord-277665-ac8txr3h 324 5 condition condition NN cord-277665-ac8txr3h 324 6 became become VBD cord-277665-ac8txr3h 324 7 normal normal JJ cord-277665-ac8txr3h 324 8 again again RB cord-277665-ac8txr3h 324 9 within within IN cord-277665-ac8txr3h 324 10 1 1 CD cord-277665-ac8txr3h 324 11 day day NN cord-277665-ac8txr3h 324 12 . . . cord-277665-ac8txr3h 325 1 The the DT cord-277665-ac8txr3h 325 2 safety safety NN cord-277665-ac8txr3h 325 3 and and CC cord-277665-ac8txr3h 325 4 effectiveness effectiveness NN cord-277665-ac8txr3h 325 5 of of IN cord-277665-ac8txr3h 325 6 nanosystems nanosystem NNS cord-277665-ac8txr3h 325 7 and and CC cord-277665-ac8txr3h 325 8 platforms platform NNS cord-277665-ac8txr3h 325 9 made make VBN cord-277665-ac8txr3h 325 10 of of IN cord-277665-ac8txr3h 325 11 NDs nd NNS cord-277665-ac8txr3h 325 12 will will MD cord-277665-ac8txr3h 325 13 fully fully RB cord-277665-ac8txr3h 325 14 depend depend VB cord-277665-ac8txr3h 325 15 on on IN cord-277665-ac8txr3h 325 16 their -PRON- PRP$ cord-277665-ac8txr3h 325 17 compatibility compatibility NN cord-277665-ac8txr3h 325 18 with with IN cord-277665-ac8txr3h 325 19 human human JJ cord-277665-ac8txr3h 325 20 organs organ NNS cord-277665-ac8txr3h 325 21 , , , cord-277665-ac8txr3h 325 22 tissues tissue NNS cord-277665-ac8txr3h 325 23 , , , cord-277665-ac8txr3h 325 24 cells cell NNS cord-277665-ac8txr3h 325 25 , , , cord-277665-ac8txr3h 325 26 and and CC cord-277665-ac8txr3h 325 27 cellular cellular JJ cord-277665-ac8txr3h 325 28 organelles organelle NNS cord-277665-ac8txr3h 325 29 . . . cord-277665-ac8txr3h 326 1 Extensive extensive JJ cord-277665-ac8txr3h 326 2 thorough thorough JJ cord-277665-ac8txr3h 326 3 research research NN cord-277665-ac8txr3h 326 4 has have VBZ cord-277665-ac8txr3h 326 5 yet yet RB cord-277665-ac8txr3h 326 6 to to TO cord-277665-ac8txr3h 326 7 be be VB cord-277665-ac8txr3h 326 8 done do VBN cord-277665-ac8txr3h 326 9 to to TO cord-277665-ac8txr3h 326 10 clearly clearly RB cord-277665-ac8txr3h 326 11 establish establish VB cord-277665-ac8txr3h 326 12 physiological physiological JJ cord-277665-ac8txr3h 326 13 , , , cord-277665-ac8txr3h 326 14 immunological immunological JJ cord-277665-ac8txr3h 326 15 , , , cord-277665-ac8txr3h 326 16 and and CC cord-277665-ac8txr3h 326 17 cytological cytological JJ cord-277665-ac8txr3h 326 18 responses response NNS cord-277665-ac8txr3h 326 19 of of IN cord-277665-ac8txr3h 326 20 the the DT cord-277665-ac8txr3h 326 21 human human JJ cord-277665-ac8txr3h 326 22 body body NN cord-277665-ac8txr3h 326 23 to to IN cord-277665-ac8txr3h 326 24 ND ND NNP cord-277665-ac8txr3h 326 25 particles particle NNS cord-277665-ac8txr3h 326 26 and and CC cord-277665-ac8txr3h 326 27 films film NNS cord-277665-ac8txr3h 326 28 . . . cord-277665-ac8txr3h 327 1 In in IN cord-277665-ac8txr3h 327 2 this this DT cord-277665-ac8txr3h 327 3 review review NN cord-277665-ac8txr3h 327 4 , , , cord-277665-ac8txr3h 327 5 methods method NNS cord-277665-ac8txr3h 327 6 of of IN cord-277665-ac8txr3h 327 7 surface surface NN cord-277665-ac8txr3h 327 8 modification modification NN cord-277665-ac8txr3h 327 9 were be VBD cord-277665-ac8txr3h 327 10 discussed discuss VBN cord-277665-ac8txr3h 327 11 for for IN cord-277665-ac8txr3h 327 12 the the DT cord-277665-ac8txr3h 327 13 development development NN cord-277665-ac8txr3h 327 14 of of IN cord-277665-ac8txr3h 327 15 functionalized functionalize VBN cord-277665-ac8txr3h 327 16 diamond diamond NN cord-277665-ac8txr3h 327 17 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 327 18 for for IN cord-277665-ac8txr3h 327 19 biomedical biomedical JJ cord-277665-ac8txr3h 327 20 applications application NNS cord-277665-ac8txr3h 327 21 . . . cord-277665-ac8txr3h 328 1 To to TO cord-277665-ac8txr3h 328 2 be be VB cord-277665-ac8txr3h 328 3 used use VBN cord-277665-ac8txr3h 328 4 in in IN cord-277665-ac8txr3h 328 5 biomedical biomedical JJ cord-277665-ac8txr3h 328 6 applications application NNS cord-277665-ac8txr3h 328 7 , , , cord-277665-ac8txr3h 328 8 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 328 9 must must MD cord-277665-ac8txr3h 328 10 be be VB cord-277665-ac8txr3h 328 11 biocompatible biocompatible JJ cord-277665-ac8txr3h 328 12 , , , cord-277665-ac8txr3h 328 13 non non JJ cord-277665-ac8txr3h 328 14 - - JJ cord-277665-ac8txr3h 328 15 toxic toxic JJ cord-277665-ac8txr3h 328 16 , , , cord-277665-ac8txr3h 328 17 non non JJ cord-277665-ac8txr3h 328 18 - - JJ cord-277665-ac8txr3h 328 19 detective detective JJ cord-277665-ac8txr3h 328 20 by by IN cord-277665-ac8txr3h 328 21 immune immune JJ cord-277665-ac8txr3h 328 22 systems system NNS cord-277665-ac8txr3h 328 23 , , , cord-277665-ac8txr3h 328 24 and and CC cord-277665-ac8txr3h 328 25 should should MD cord-277665-ac8txr3h 328 26 not not RB cord-277665-ac8txr3h 328 27 induce induce VB cord-277665-ac8txr3h 328 28 side side NN cord-277665-ac8txr3h 328 29 effects effect NNS cord-277665-ac8txr3h 328 30 . . . cord-277665-ac8txr3h 329 1 Size size NN cord-277665-ac8txr3h 329 2 control control NN cord-277665-ac8txr3h 329 3 of of IN cord-277665-ac8txr3h 329 4 particles particle NNS cord-277665-ac8txr3h 329 5 is be VBZ cord-277665-ac8txr3h 329 6 a a DT cord-277665-ac8txr3h 329 7 prerequisite prerequisite NN cord-277665-ac8txr3h 329 8 for for IN cord-277665-ac8txr3h 329 9 biomedical biomedical JJ cord-277665-ac8txr3h 329 10 applications application NNS cord-277665-ac8txr3h 329 11 . . . cord-277665-ac8txr3h 330 1 To to TO cord-277665-ac8txr3h 330 2 meet meet VB cord-277665-ac8txr3h 330 3 all all PDT cord-277665-ac8txr3h 330 4 these these DT cord-277665-ac8txr3h 330 5 criteria criterion NNS cord-277665-ac8txr3h 330 6 , , , cord-277665-ac8txr3h 330 7 the the DT cord-277665-ac8txr3h 330 8 diameter diameter NN cord-277665-ac8txr3h 330 9 of of IN cord-277665-ac8txr3h 330 10 particles particle NNS cord-277665-ac8txr3h 330 11 should should MD cord-277665-ac8txr3h 330 12 be be VB cord-277665-ac8txr3h 330 13 less less JJR cord-277665-ac8txr3h 330 14 than than IN cord-277665-ac8txr3h 330 15 100 100 CD cord-277665-ac8txr3h 330 16 nm nm NN cord-277665-ac8txr3h 330 17 and and CC cord-277665-ac8txr3h 330 18 their -PRON- PRP$ cord-277665-ac8txr3h 330 19 surfaces surface NNS cord-277665-ac8txr3h 330 20 should should MD cord-277665-ac8txr3h 330 21 be be VB cord-277665-ac8txr3h 330 22 modified modify VBN cord-277665-ac8txr3h 330 23 by by IN cord-277665-ac8txr3h 330 24 hydrophilic hydrophilic JJ cord-277665-ac8txr3h 330 25 moieties moiety NNS cord-277665-ac8txr3h 330 26 . . . cord-277665-ac8txr3h 331 1 Such such JJ cord-277665-ac8txr3h 331 2 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 331 3 are be VBP cord-277665-ac8txr3h 331 4 likely likely JJ cord-277665-ac8txr3h 331 5 to to TO cord-277665-ac8txr3h 331 6 avoid avoid VB cord-277665-ac8txr3h 331 7 uptake uptake NN cord-277665-ac8txr3h 331 8 by by IN cord-277665-ac8txr3h 331 9 the the DT cord-277665-ac8txr3h 331 10 reticuloendothelial reticuloendothelial JJ cord-277665-ac8txr3h 331 11 system system NN cord-277665-ac8txr3h 331 12 and and CC cord-277665-ac8txr3h 331 13 remain remain VB cord-277665-ac8txr3h 331 14 in in IN cord-277665-ac8txr3h 331 15 blood blood NN cord-277665-ac8txr3h 331 16 at at IN cord-277665-ac8txr3h 331 17 a a DT cord-277665-ac8txr3h 331 18 high high JJ cord-277665-ac8txr3h 331 19 enough enough JJ cord-277665-ac8txr3h 331 20 concen concen NN cord-277665-ac8txr3h 331 21 - - HYPH cord-277665-ac8txr3h 331 22 tration tration NN cord-277665-ac8txr3h 331 23 to to TO cord-277665-ac8txr3h 331 24 reach reach VB cord-277665-ac8txr3h 331 25 the the DT cord-277665-ac8txr3h 331 26 target target NN cord-277665-ac8txr3h 331 27 organs organ NNS cord-277665-ac8txr3h 331 28 , , , cord-277665-ac8txr3h 331 29 tissues tissue NNS cord-277665-ac8txr3h 331 30 , , , cord-277665-ac8txr3h 331 31 or or CC cord-277665-ac8txr3h 331 32 cells cell NNS cord-277665-ac8txr3h 331 33 . . . cord-277665-ac8txr3h 332 1 The the DT cord-277665-ac8txr3h 332 2 surface surface NN cord-277665-ac8txr3h 332 3 of of IN cord-277665-ac8txr3h 332 4 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 332 5 has have VBZ cord-277665-ac8txr3h 332 6 to to TO cord-277665-ac8txr3h 332 7 be be VB cord-277665-ac8txr3h 332 8 preliminarily preliminarily RB cord-277665-ac8txr3h 332 9 modified modify VBN cord-277665-ac8txr3h 332 10 by by IN cord-277665-ac8txr3h 332 11 functional functional JJ cord-277665-ac8txr3h 332 12 ligands ligand NNS cord-277665-ac8txr3h 332 13 with with IN cord-277665-ac8txr3h 332 14 a a DT cord-277665-ac8txr3h 332 15 high high JJ cord-277665-ac8txr3h 332 16 affinity affinity NN cord-277665-ac8txr3h 332 17 to to IN cord-277665-ac8txr3h 332 18 a a DT cord-277665-ac8txr3h 332 19 disease disease NN cord-277665-ac8txr3h 332 20 site site NN cord-277665-ac8txr3h 332 21 to to TO cord-277665-ac8txr3h 332 22 achieve achieve VB cord-277665-ac8txr3h 332 23 site site NN cord-277665-ac8txr3h 332 24 - - HYPH cord-277665-ac8txr3h 332 25 specific specific JJ cord-277665-ac8txr3h 332 26 delivery delivery NN cord-277665-ac8txr3h 332 27 . . . cord-277665-ac8txr3h 333 1 In in IN cord-277665-ac8txr3h 333 2 many many JJ cord-277665-ac8txr3h 333 3 cases case NNS cord-277665-ac8txr3h 333 4 , , , cord-277665-ac8txr3h 333 5 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 333 6 may may MD cord-277665-ac8txr3h 333 7 encapsulate encapsulate VB cord-277665-ac8txr3h 333 8 and and CC cord-277665-ac8txr3h 333 9 protect protect VB cord-277665-ac8txr3h 333 10 therapeutic therapeutic JJ cord-277665-ac8txr3h 333 11 agents agent NNS cord-277665-ac8txr3h 333 12 against against IN cord-277665-ac8txr3h 333 13 enzymes enzyme NNS cord-277665-ac8txr3h 333 14 and and CC cord-277665-ac8txr3h 333 15 hydrolysis hydrolysis NN cord-277665-ac8txr3h 333 16 ; ; : cord-277665-ac8txr3h 333 17 it -PRON- PRP cord-277665-ac8txr3h 333 18 is be VBZ cord-277665-ac8txr3h 333 19 not not RB cord-277665-ac8txr3h 333 20 clear clear JJ cord-277665-ac8txr3h 333 21 yet yet RB cord-277665-ac8txr3h 333 22 how how WRB cord-277665-ac8txr3h 333 23 nanodiamond nanodiamond JJ cord-277665-ac8txr3h 333 24 particles particle NNS cord-277665-ac8txr3h 333 25 can can MD cord-277665-ac8txr3h 333 26 satisfy satisfy VB cord-277665-ac8txr3h 333 27 this this DT cord-277665-ac8txr3h 333 28 requirement requirement NN cord-277665-ac8txr3h 333 29 . . . cord-277665-ac8txr3h 334 1 It -PRON- PRP cord-277665-ac8txr3h 334 2 is be VBZ cord-277665-ac8txr3h 334 3 obvious obvious JJ cord-277665-ac8txr3h 334 4 from from IN cord-277665-ac8txr3h 334 5 the the DT cord-277665-ac8txr3h 334 6 reviewed review VBN cord-277665-ac8txr3h 334 7 literature literature NN cord-277665-ac8txr3h 334 8 that that WDT cord-277665-ac8txr3h 334 9 both both CC cord-277665-ac8txr3h 334 10 nanodiamond nanodiamond NNP cord-277665-ac8txr3h 334 11 particulates particulate NNS cord-277665-ac8txr3h 334 12 and and CC cord-277665-ac8txr3h 334 13 films film NNS cord-277665-ac8txr3h 334 14 have have VBP cord-277665-ac8txr3h 334 15 become become VBN cord-277665-ac8txr3h 334 16 very very RB cord-277665-ac8txr3h 334 17 popular popular JJ cord-277665-ac8txr3h 334 18 objects object NNS cord-277665-ac8txr3h 334 19 in in IN cord-277665-ac8txr3h 334 20 biomedical biomedical JJ cord-277665-ac8txr3h 334 21 research research NN cord-277665-ac8txr3h 334 22 . . . cord-277665-ac8txr3h 335 1 Performance performance NN cord-277665-ac8txr3h 335 2 of of IN cord-277665-ac8txr3h 335 3 irradiated irradiate VBN cord-277665-ac8txr3h 335 4 CVD CVD NNP cord-277665-ac8txr3h 335 5 diamond diamond NN cord-277665-ac8txr3h 335 6 micro micro JJ cord-277665-ac8txr3h 335 7 - - JJ cord-277665-ac8txr3h 335 8 strip strip JJ cord-277665-ac8txr3h 335 9 sensors sensor NNS cord-277665-ac8txr3h 335 10 Nanotechnology Nanotechnology NNP cord-277665-ac8txr3h 335 11 in in IN cord-277665-ac8txr3h 335 12 biology biology NN cord-277665-ac8txr3h 335 13 : : : cord-277665-ac8txr3h 335 14 The the DT cord-277665-ac8txr3h 335 15 good good NN cord-277665-ac8txr3h 335 16 of of IN cord-277665-ac8txr3h 335 17 small small JJ cord-277665-ac8txr3h 335 18 things thing NNS cord-277665-ac8txr3h 335 19 . . . cord-277665-ac8txr3h 336 1 The the DT cord-277665-ac8txr3h 336 2 Economist economist NN cord-277665-ac8txr3h 336 3 Benign benign JJ cord-277665-ac8txr3h 336 4 response response NN cord-277665-ac8txr3h 336 5 to to IN cord-277665-ac8txr3h 336 6 particles particle NNS cord-277665-ac8txr3h 336 7 of of IN cord-277665-ac8txr3h 336 8 diamond diamond NN cord-277665-ac8txr3h 336 9 and and CC cord-277665-ac8txr3h 336 10 SiC sic NN cord-277665-ac8txr3h 336 11 : : : cord-277665-ac8txr3h 336 12 Bone bone NN cord-277665-ac8txr3h 336 13 chamber chamber NN cord-277665-ac8txr3h 336 14 studies study NNS cord-277665-ac8txr3h 336 15 of of IN cord-277665-ac8txr3h 336 16 new new JJ cord-277665-ac8txr3h 336 17 joint joint JJ cord-277665-ac8txr3h 336 18 replacement replacement NN cord-277665-ac8txr3h 336 19 coating coating NN cord-277665-ac8txr3h 336 20 materials material NNS cord-277665-ac8txr3h 336 21 in in IN cord-277665-ac8txr3h 336 22 rabbits rabbit NNS cord-277665-ac8txr3h 336 23 PLGA PLGA NNP cord-277665-ac8txr3h 336 24 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 336 25 in in IN cord-277665-ac8txr3h 336 26 drug drug NN cord-277665-ac8txr3h 336 27 delivery delivery NN cord-277665-ac8txr3h 336 28 : : : cord-277665-ac8txr3h 337 1 The the DT cord-277665-ac8txr3h 337 2 state state NN cord-277665-ac8txr3h 337 3 of of IN cord-277665-ac8txr3h 337 4 the the DT cord-277665-ac8txr3h 337 5 art art NN cord-277665-ac8txr3h 337 6 Agonists agonist NNS cord-277665-ac8txr3h 337 7 and and CC cord-277665-ac8txr3h 337 8 antagonists antagonist NNS cord-277665-ac8txr3h 337 9 acting act VBG cord-277665-ac8txr3h 337 10 at at IN cord-277665-ac8txr3h 337 11 P2X(7 P2X(7 NNP cord-277665-ac8txr3h 337 12 ) ) -RRB- cord-277665-ac8txr3h 338 1 receptor receptor NNP cord-277665-ac8txr3h 338 2 Analysis Analysis NNP cord-277665-ac8txr3h 338 3 of of IN cord-277665-ac8txr3h 338 4 the the DT cord-277665-ac8txr3h 338 5 coagulation coagulation NN cord-277665-ac8txr3h 338 6 of of IN cord-277665-ac8txr3h 338 7 human human JJ cord-277665-ac8txr3h 338 8 blood blood NN cord-277665-ac8txr3h 338 9 cells cell NNS cord-277665-ac8txr3h 338 10 on on IN cord-277665-ac8txr3h 338 11 diamond diamond NN cord-277665-ac8txr3h 338 12 surfaces surface NNS cord-277665-ac8txr3h 338 13 by by IN cord-277665-ac8txr3h 338 14 atomic atomic JJ cord-277665-ac8txr3h 338 15 force force NN cord-277665-ac8txr3h 338 16 microscopy microscopy NN cord-277665-ac8txr3h 338 17 Behar Behar NNP cord-277665-ac8txr3h 338 18 - - HYPH cord-277665-ac8txr3h 338 19 Cohen Cohen NNP cord-277665-ac8txr3h 338 20 F F NNP cord-277665-ac8txr3h 338 21 ( ( -LRB- cord-277665-ac8txr3h 338 22 20905 20905 CD cord-277665-ac8txr3h 338 23 ) ) -RRB- cord-277665-ac8txr3h 339 1 Nanoparticles nanoparticle NNS cord-277665-ac8txr3h 339 2 for for IN cord-277665-ac8txr3h 339 3 gene gene NN cord-277665-ac8txr3h 339 4 delivery delivery NN cord-277665-ac8txr3h 339 5 to to IN cord-277665-ac8txr3h 339 6 retinal retinal JJ cord-277665-ac8txr3h 339 7 pigment pigment NN cord-277665-ac8txr3h 339 8 epithelial epithelial NN cord-277665-ac8txr3h 339 9 cells cell NNS cord-277665-ac8txr3h 339 10 Synthetic synthetic JJ cord-277665-ac8txr3h 339 11 biocompatible biocompatible JJ cord-277665-ac8txr3h 339 12 cyclodextrin cyclodextrin NN cord-277665-ac8txr3h 339 13 - - HYPH cord-277665-ac8txr3h 339 14 based base VBN cord-277665-ac8txr3h 339 15 constructs construct NNS cord-277665-ac8txr3h 339 16 for for IN cord-277665-ac8txr3h 339 17 local local JJ cord-277665-ac8txr3h 339 18 gene gene NN cord-277665-ac8txr3h 339 19 delivery delivery NN cord-277665-ac8txr3h 339 20 to to TO cord-277665-ac8txr3h 339 21 improve improve VB cord-277665-ac8txr3h 339 22 cutaneous cutaneous JJ cord-277665-ac8txr3h 339 23 wound wound NN cord-277665-ac8txr3h 339 24 healing heal VBG cord-277665-ac8txr3h 339 25 Charged charged JJ cord-277665-ac8txr3h 339 26 particle particle NN cord-277665-ac8txr3h 339 27 detectors detector NNS cord-277665-ac8txr3h 339 28 made make VBN cord-277665-ac8txr3h 339 29 of of IN cord-277665-ac8txr3h 339 30 singlecrystal singlecrystal NNP cord-277665-ac8txr3h 339 31 diamond diamond NNP cord-277665-ac8txr3h 339 32 Application Application NNP cord-277665-ac8txr3h 339 33 of of IN cord-277665-ac8txr3h 339 34 modified modify VBN cord-277665-ac8txr3h 339 35 nanodiamonds nanodiamond NNS cord-277665-ac8txr3h 339 36 as as IN cord-277665-ac8txr3h 339 37 catalysts catalyst NNS cord-277665-ac8txr3h 339 38 of of IN cord-277665-ac8txr3h 339 39 heterogeneous heterogeneous JJ cord-277665-ac8txr3h 339 40 and and CC cord-277665-ac8txr3h 339 41 electrochemical electrochemical JJ cord-277665-ac8txr3h 339 42 catalyses catalysis NNS cord-277665-ac8txr3h 339 43 Nanodiamonds Nanodiamonds NNPS cord-277665-ac8txr3h 339 44 for for IN cord-277665-ac8txr3h 339 45 biological biological JJ cord-277665-ac8txr3h 339 46 investigations investigation NNS cord-277665-ac8txr3h 339 47 Applications application NNS cord-277665-ac8txr3h 339 48 of of IN cord-277665-ac8txr3h 339 49 nanodiamonds nanodiamond NNS cord-277665-ac8txr3h 339 50 for for IN cord-277665-ac8txr3h 339 51 separation separation NN cord-277665-ac8txr3h 339 52 and and CC cord-277665-ac8txr3h 339 53 purification purification NN cord-277665-ac8txr3h 339 54 of of IN cord-277665-ac8txr3h 339 55 proteins protein NNS cord-277665-ac8txr3h 340 1 A a DT cord-277665-ac8txr3h 340 2 study study NN cord-277665-ac8txr3h 340 3 on on IN cord-277665-ac8txr3h 340 4 the the DT cord-277665-ac8txr3h 340 5 action action NN cord-277665-ac8txr3h 340 6 of of IN cord-277665-ac8txr3h 340 7 ozone ozone NN cord-277665-ac8txr3h 340 8 and and CC cord-277665-ac8txr3h 340 9 on on IN cord-277665-ac8txr3h 340 10 the the DT cord-277665-ac8txr3h 340 11 thermal thermal JJ cord-277665-ac8txr3h 340 12 stability stability NN cord-277665-ac8txr3h 340 13 of of IN cord-277665-ac8txr3h 340 14 nanodiamond nanodiamond JJ cord-277665-ac8txr3h 340 15 Selective selective JJ cord-277665-ac8txr3h 340 16 inhibition inhibition NN cord-277665-ac8txr3h 340 17 of of IN cord-277665-ac8txr3h 340 18 the the DT cord-277665-ac8txr3h 340 19 oxidation oxidation NN cord-277665-ac8txr3h 340 20 of of IN cord-277665-ac8txr3h 340 21 nanodiamonds nanodiamond NNS cord-277665-ac8txr3h 340 22 for for IN cord-277665-ac8txr3h 340 23 their -PRON- PRP$ cord-277665-ac8txr3h 340 24 cleaning cleaning NN cord-277665-ac8txr3h 340 25 Progress Progress NNP cord-277665-ac8txr3h 340 26 in in IN cord-277665-ac8txr3h 340 27 enzyme enzyme NN cord-277665-ac8txr3h 340 28 - - HYPH cord-277665-ac8txr3h 340 29 based base VBN cord-277665-ac8txr3h 340 30 biosensors biosensor NNS cord-277665-ac8txr3h 340 31 using use VBG cord-277665-ac8txr3h 340 32 optical optical JJ cord-277665-ac8txr3h 340 33 transducers transducer NNS cord-277665-ac8txr3h 340 34 Electroanalysis Electroanalysis NNP cord-277665-ac8txr3h 340 35 at at IN cord-277665-ac8txr3h 340 36 diamondlike diamondlike NN cord-277665-ac8txr3h 340 37 and and CC cord-277665-ac8txr3h 340 38 doped dope VBN cord-277665-ac8txr3h 340 39 - - HYPH cord-277665-ac8txr3h 340 40 diamond diamond NN cord-277665-ac8txr3h 340 41 electrodes electrode NNS cord-277665-ac8txr3h 341 1 Easy easy JJ cord-277665-ac8txr3h 341 2 access access NN cord-277665-ac8txr3h 341 3 to to IN cord-277665-ac8txr3h 341 4 watersoluble watersoluble JJ cord-277665-ac8txr3h 341 5 fullerene fullerene NN cord-277665-ac8txr3h 341 6 derivatives derivative NNS cord-277665-ac8txr3h 341 7 via via IN cord-277665-ac8txr3h 341 8 1,3-dipolar 1,3-dipolar JJ cord-277665-ac8txr3h 341 9 cycloadditions cycloaddition NNS cord-277665-ac8txr3h 341 10 of of IN cord-277665-ac8txr3h 341 11 azomethine azomethine NNP cord-277665-ac8txr3h 341 12 ylides ylides NNP cord-277665-ac8txr3h 341 13 to to IN cord-277665-ac8txr3h 341 14 C60 C60 NNP cord-277665-ac8txr3h 341 15 Biosensors Biosensors NNP cord-277665-ac8txr3h 341 16 for for IN cord-277665-ac8txr3h 341 17 the the DT cord-277665-ac8txr3h 341 18 detection detection NN cord-277665-ac8txr3h 341 19 of of IN cord-277665-ac8txr3h 341 20 bacteria bacteria NNS cord-277665-ac8txr3h 341 21 Detonation detonation NN cord-277665-ac8txr3h 341 22 synthesis synthesis NN cord-277665-ac8txr3h 341 23 ultradispersed ultradisperse VBD cord-277665-ac8txr3h 341 24 diamonds diamond NNS cord-277665-ac8txr3h 341 25 : : : cord-277665-ac8txr3h 342 1 Properties property NNS cord-277665-ac8txr3h 342 2 and and CC cord-277665-ac8txr3h 342 3 applications application NNS cord-277665-ac8txr3h 342 4 Detonation detonation NN cord-277665-ac8txr3h 342 5 - - HYPH cord-277665-ac8txr3h 342 6 synthesized synthesize VBN cord-277665-ac8txr3h 342 7 nanodiamonds nanodiamond NNS cord-277665-ac8txr3h 342 8 and and CC cord-277665-ac8txr3h 342 9 the the DT cord-277665-ac8txr3h 342 10 possibility possibility NN cord-277665-ac8txr3h 342 11 to to TO cord-277665-ac8txr3h 342 12 develop develop VB cord-277665-ac8txr3h 342 13 a a DT cord-277665-ac8txr3h 342 14 new new JJ cord-277665-ac8txr3h 342 15 generation generation NN cord-277665-ac8txr3h 342 16 of of IN cord-277665-ac8txr3h 342 17 medicines medicine NNS cord-277665-ac8txr3h 342 18 Detonation detonation NN cord-277665-ac8txr3h 342 19 and and CC cord-277665-ac8txr3h 342 20 shock shock NN cord-277665-ac8txr3h 342 21 synthesis synthesis NN cord-277665-ac8txr3h 342 22 of of IN cord-277665-ac8txr3h 342 23 nanodiamonds nanodiamond NNS cord-277665-ac8txr3h 342 24 B B NNP cord-277665-ac8txr3h 342 25 Synthesis Synthesis NNP cord-277665-ac8txr3h 342 26 , , , cord-277665-ac8txr3h 342 27 antimicrobial antimicrobial NN cord-277665-ac8txr3h 342 28 , , , cord-277665-ac8txr3h 342 29 and and CC cord-277665-ac8txr3h 342 30 anti anti JJ cord-277665-ac8txr3h 342 31 - - JJ cord-277665-ac8txr3h 342 32 HIV-1 hiv-1 JJ cord-277665-ac8txr3h 342 33 activity activity NN cord-277665-ac8txr3h 342 34 of of IN cord-277665-ac8txr3h 342 35 certain certain JJ cord-277665-ac8txr3h 342 36 5-(I 5-(i CD cord-277665-ac8txr3h 342 37 - - HYPH cord-277665-ac8txr3h 342 38 adamantyl)-2-substituted adamantyl)-2-substitute VBN cord-277665-ac8txr3h 342 39 thio-1,3,4-oxadiazoles thio-1,3,4-oxadiazole NNS cord-277665-ac8txr3h 342 40 and and CC cord-277665-ac8txr3h 342 41 5-(1-adamantyl)-3-substituted 5-(1-adamantyl)-3-substituted CD cord-277665-ac8txr3h 343 1 aminomethyl-1,3,4-oxadiazoline-2-thiones aminomethyl-1,3,4-oxadiazoline-2-thiones NNPS cord-277665-ac8txr3h 343 2 Synthesis Synthesis NNP cord-277665-ac8txr3h 343 3 , , , cord-277665-ac8txr3h 343 4 antitumor antitumor JJ cord-277665-ac8txr3h 343 5 activity activity NN cord-277665-ac8txr3h 343 6 , , , cord-277665-ac8txr3h 343 7 and and CC cord-277665-ac8txr3h 343 8 anti anti JJ cord-277665-ac8txr3h 343 9 - - JJ cord-277665-ac8txr3h 343 10 HIV-1 hiv-1 JJ cord-277665-ac8txr3h 343 11 testing testing NN cord-277665-ac8txr3h 343 12 of of IN cord-277665-ac8txr3h 343 13 certain certain JJ cord-277665-ac8txr3h 343 14 heterocyclic heterocyclic JJ cord-277665-ac8txr3h 343 15 systems system NNS cord-277665-ac8txr3h 343 16 containing contain VBG cord-277665-ac8txr3h 343 17 an an DT cord-277665-ac8txr3h 343 18 adamantane adamantane NNP cord-277665-ac8txr3h 343 19 nucleus nucleus NN cord-277665-ac8txr3h 343 20 Nanomedicine Nanomedicine NNP cord-277665-ac8txr3h 343 21 , , , cord-277665-ac8txr3h 343 22 Volume volume NN cord-277665-ac8txr3h 343 23 I i NN cord-277665-ac8txr3h 343 24 : : : cord-277665-ac8txr3h 343 25 Basic Basic NNP cord-277665-ac8txr3h 343 26 Capabilities Capabilities NNPS cord-277665-ac8txr3h 343 27 pH pH NNP cord-277665-ac8txr3h 343 28 sensors sensor NNS cord-277665-ac8txr3h 343 29 based base VBN cord-277665-ac8txr3h 343 30 on on IN cord-277665-ac8txr3h 343 31 hydrogenated hydrogenate VBN cord-277665-ac8txr3h 343 32 diamond diamond NN cord-277665-ac8txr3h 343 33 surfaces surface VBZ cord-277665-ac8txr3h 343 34 Diamond diamond NN cord-277665-ac8txr3h 343 35 - - HYPH cord-277665-ac8txr3h 343 36 like like JJ cord-277665-ac8txr3h 343 37 carbon carbon NN cord-277665-ac8txr3h 343 38 coatings coating NNS cord-277665-ac8txr3h 343 39 as as IN cord-277665-ac8txr3h 343 40 biocompatible biocompatible JJ cord-277665-ac8txr3h 343 41 materials material NNS cord-277665-ac8txr3h 343 42 - - : cord-277665-ac8txr3h 343 43 An an DT cord-277665-ac8txr3h 343 44 overview overview NN cord-277665-ac8txr3h 343 45 Conductive Conductive NNP cord-277665-ac8txr3h 343 46 polymer polymer NN cord-277665-ac8txr3h 343 47 - - HYPH cord-277665-ac8txr3h 343 48 modified modify VBN cord-277665-ac8txr3h 343 49 boron boron NN cord-277665-ac8txr3h 343 50 - - HYPH cord-277665-ac8txr3h 343 51 doped dope VBN cord-277665-ac8txr3h 343 52 diamond diamond NN cord-277665-ac8txr3h 343 53 for for IN cord-277665-ac8txr3h 343 54 DNA dna NN cord-277665-ac8txr3h 343 55 hybridization hybridization NN cord-277665-ac8txr3h 343 56 analysis analysis NN cord-277665-ac8txr3h 343 57 Protein Protein NNP cord-277665-ac8txr3h 343 58 - - HYPH cord-277665-ac8txr3h 343 59 modified modify VBN cord-277665-ac8txr3h 343 60 nanocrystalline nanocrystalline NNP cord-277665-ac8txr3h 343 61 diamond diamond NN cord-277665-ac8txr3h 343 62 thin thin JJ cord-277665-ac8txr3h 343 63 films film NNS cord-277665-ac8txr3h 343 64 for for IN cord-277665-ac8txr3h 343 65 biosensor biosensor NN cord-277665-ac8txr3h 343 66 applications application NNS cord-277665-ac8txr3h 344 1 Quartz quartz NN cord-277665-ac8txr3h 344 2 - - HYPH cord-277665-ac8txr3h 344 3 dust dust NN cord-277665-ac8txr3h 344 4 - - HYPH cord-277665-ac8txr3h 344 5 induced induce VBN cord-277665-ac8txr3h 344 6 production production NN cord-277665-ac8txr3h 344 7 of of IN cord-277665-ac8txr3h 344 8 reactive reactive JJ cord-277665-ac8txr3h 344 9 oxygen oxygen NN cord-277665-ac8txr3h 344 10 metabolites metabolite NNS cord-277665-ac8txr3h 344 11 by by IN cord-277665-ac8txr3h 344 12 human human NN cord-277665-ac8txr3h 344 13 - - HYPH cord-277665-ac8txr3h 344 14 granulocytes granulocyte NNS cord-277665-ac8txr3h 344 15 Oxygen oxygen NN cord-277665-ac8txr3h 344 16 radical radical JJ cord-277665-ac8txr3h 344 17 production production NN cord-277665-ac8txr3h 344 18 by by IN cord-277665-ac8txr3h 344 19 horse horse NN cord-277665-ac8txr3h 344 20 and and CC cord-277665-ac8txr3h 344 21 pig pig NN cord-277665-ac8txr3h 344 22 neutrophils neutrophil NNS cord-277665-ac8txr3h 344 23 induced induce VBN cord-277665-ac8txr3h 344 24 by by IN cord-277665-ac8txr3h 344 25 a a DT cord-277665-ac8txr3h 344 26 range range NN cord-277665-ac8txr3h 344 27 of of IN cord-277665-ac8txr3h 344 28 crystals crystal NNS cord-277665-ac8txr3h 344 29 Structural structural JJ cord-277665-ac8txr3h 344 30 requirements requirement NNS cord-277665-ac8txr3h 344 31 for for IN cord-277665-ac8txr3h 344 32 inhibitors inhibitor NNS cord-277665-ac8txr3h 344 33 of of IN cord-277665-ac8txr3h 344 34 cytochromes cytochrome NNS cord-277665-ac8txr3h 345 1 P4502B p4502b NN cord-277665-ac8txr3h 345 2 : : : cord-277665-ac8txr3h 346 1 Assessment assessment NN cord-277665-ac8txr3h 346 2 of of IN cord-277665-ac8txr3h 346 3 the the DT cord-277665-ac8txr3h 346 4 enzyme enzyme NN cord-277665-ac8txr3h 346 5 interaction interaction NN cord-277665-ac8txr3h 346 6 with with IN cord-277665-ac8txr3h 346 7 diamondoids diamondoids NNP cord-277665-ac8txr3h 346 8 Adsorption Adsorption NNP cord-277665-ac8txr3h 346 9 and and CC cord-277665-ac8txr3h 346 10 immobilization immobilization NN cord-277665-ac8txr3h 346 11 of of IN cord-277665-ac8txr3h 346 12 cytochrome cytochrome NN cord-277665-ac8txr3h 346 13 c c NN cord-277665-ac8txr3h 346 14 on on IN cord-277665-ac8txr3h 346 15 nanodiamonds nanodiamonds NNP cord-277665-ac8txr3h 346 16 Immobilization Immobilization NNP cord-277665-ac8txr3h 346 17 of of IN cord-277665-ac8txr3h 346 18 antibodies antibody NNS cord-277665-ac8txr3h 346 19 and and CC cord-277665-ac8txr3h 346 20 bacterial bacterial JJ cord-277665-ac8txr3h 346 21 binding binding NN cord-277665-ac8txr3h 346 22 on on IN cord-277665-ac8txr3h 346 23 nanodiamond nanodiamond NN cord-277665-ac8txr3h 346 24 and and CC cord-277665-ac8txr3h 346 25 carbon carbon NN cord-277665-ac8txr3h 346 26 nanotubes nanotube NNS cord-277665-ac8txr3h 346 27 for for IN cord-277665-ac8txr3h 346 28 biosensor biosensor NN cord-277665-ac8txr3h 346 29 applications application NNS cord-277665-ac8txr3h 346 30 Chemical chemical JJ cord-277665-ac8txr3h 346 31 reaction reaction NN cord-277665-ac8txr3h 346 32 of of IN cord-277665-ac8txr3h 346 33 hydrogenated hydrogenate VBN cord-277665-ac8txr3h 346 34 diamond diamond NN cord-277665-ac8txr3h 346 35 surface surface NN cord-277665-ac8txr3h 346 36 with with IN cord-277665-ac8txr3h 346 37 peroxide peroxide NN cord-277665-ac8txr3h 346 38 radical radical JJ cord-277665-ac8txr3h 346 39 initiators initiator NNS cord-277665-ac8txr3h 346 40 Nanocrystalline Nanocrystalline NNP cord-277665-ac8txr3h 346 41 diamond diamond NN cord-277665-ac8txr3h 346 42 surface surface NN cord-277665-ac8txr3h 346 43 is be VBZ cord-277665-ac8txr3h 346 44 resistant resistant JJ cord-277665-ac8txr3h 346 45 to to IN cord-277665-ac8txr3h 346 46 bacterial bacterial JJ cord-277665-ac8txr3h 346 47 colonization colonization NN cord-277665-ac8txr3h 346 48 FTIR FTIR NNP cord-277665-ac8txr3h 346 49 studies study NNS cord-277665-ac8txr3h 346 50 on on IN cord-277665-ac8txr3h 346 51 the the DT cord-277665-ac8txr3h 346 52 spectral spectral JJ cord-277665-ac8txr3h 346 53 changes change NNS cord-277665-ac8txr3h 346 54 of of IN cord-277665-ac8txr3h 346 55 the the DT cord-277665-ac8txr3h 346 56 surface surface NN cord-277665-ac8txr3h 346 57 functional functional JJ cord-277665-ac8txr3h 346 58 groups group NNS cord-277665-ac8txr3h 346 59 of of IN cord-277665-ac8txr3h 346 60 ultradispersed ultradispersed JJ cord-277665-ac8txr3h 346 61 diamond diamond NN cord-277665-ac8txr3h 346 62 powder powder NN cord-277665-ac8txr3h 346 63 synthesized synthesize VBN cord-277665-ac8txr3h 346 64 by by IN cord-277665-ac8txr3h 346 65 explosive explosive JJ cord-277665-ac8txr3h 346 66 detonation detonation NN cord-277665-ac8txr3h 346 67 after after IN cord-277665-ac8txr3h 346 68 treatment treatment NN cord-277665-ac8txr3h 346 69 in in IN cord-277665-ac8txr3h 346 70 hydrogen hydrogen NN cord-277665-ac8txr3h 346 71 , , , cord-277665-ac8txr3h 346 72 nitrogen nitrogen NN cord-277665-ac8txr3h 346 73 , , , cord-277665-ac8txr3h 346 74 methane methane NN cord-277665-ac8txr3h 346 75 and and CC cord-277665-ac8txr3h 346 76 air air NN cord-277665-ac8txr3h 346 77 at at IN cord-277665-ac8txr3h 346 78 different different JJ cord-277665-ac8txr3h 346 79 temperatures temperature NNS cord-277665-ac8txr3h 347 1 Electrochemical electrochemical JJ cord-277665-ac8txr3h 347 2 behavior behavior NN cord-277665-ac8txr3h 347 3 of of IN cord-277665-ac8txr3h 347 4 diamond diamond NN cord-277665-ac8txr3h 347 5 - - HYPH cord-277665-ac8txr3h 347 6 like like JJ cord-277665-ac8txr3h 347 7 carbon carbon NN cord-277665-ac8txr3h 347 8 films film NNS cord-277665-ac8txr3h 347 9 for for IN cord-277665-ac8txr3h 347 10 biomedical biomedical JJ cord-277665-ac8txr3h 347 11 applications application NNS cord-277665-ac8txr3h 348 1 A a DT cord-277665-ac8txr3h 348 2 nonviral nonviral JJ cord-277665-ac8txr3h 348 3 DNA dna NN cord-277665-ac8txr3h 348 4 delivery delivery NN cord-277665-ac8txr3h 348 5 system system NN cord-277665-ac8txr3h 348 6 based base VBN cord-277665-ac8txr3h 348 7 on on IN cord-277665-ac8txr3h 348 8 surface surface NN cord-277665-ac8txr3h 348 9 modified modify VBN cord-277665-ac8txr3h 348 10 silicananoparticles silicananoparticle NNS cord-277665-ac8txr3h 348 11 can can MD cord-277665-ac8txr3h 348 12 efficiently efficiently RB cord-277665-ac8txr3h 348 13 transfect transfect VB cord-277665-ac8txr3h 348 14 cells cell NNS cord-277665-ac8txr3h 348 15 in in IN cord-277665-ac8txr3h 348 16 vitro vitro FW cord-277665-ac8txr3h 348 17 DNA dna NN cord-277665-ac8txr3h 348 18 - - HYPH cord-277665-ac8txr3h 348 19 modified modify VBN cord-277665-ac8txr3h 348 20 diamond diamond NN cord-277665-ac8txr3h 348 21 surfaces surface NNS cord-277665-ac8txr3h 348 22 Highaffinity Highaffinity NNP cord-277665-ac8txr3h 348 23 capture capture NN cord-277665-ac8txr3h 348 24 of of IN cord-277665-ac8txr3h 348 25 proteins protein NNS cord-277665-ac8txr3h 348 26 by by IN cord-277665-ac8txr3h 348 27 diamond diamond NN cord-277665-ac8txr3h 348 28 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 348 29 for for IN cord-277665-ac8txr3h 348 30 mass mass NNP cord-277665-ac8txr3h 348 31 spectrometric spectrometric NNP cord-277665-ac8txr3h 348 32 analysis analysis NN cord-277665-ac8txr3h 349 1 A a DT cord-277665-ac8txr3h 349 2 revision revision NN cord-277665-ac8txr3h 349 3 of of IN cord-277665-ac8txr3h 349 4 the the DT cord-277665-ac8txr3h 349 5 metabolic metabolic JJ cord-277665-ac8txr3h 349 6 disposition disposition NN cord-277665-ac8txr3h 349 7 of of IN cord-277665-ac8txr3h 349 8 amantadine amantadine NNP cord-277665-ac8txr3h 349 9 Surface Surface NNP cord-277665-ac8txr3h 349 10 - - HYPH cord-277665-ac8txr3h 349 11 modified modify VBN cord-277665-ac8txr3h 349 12 diamond diamond NN cord-277665-ac8txr3h 349 13 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 349 14 as as IN cord-277665-ac8txr3h 349 15 antigen antigen NN cord-277665-ac8txr3h 349 16 delivery delivery NN cord-277665-ac8txr3h 349 17 vehicles vehicle NNS cord-277665-ac8txr3h 349 18 situ situ VBP cord-277665-ac8txr3h 349 19 blood blood NN cord-277665-ac8txr3h 349 20 - - HYPH cord-277665-ac8txr3h 349 21 brain brain NN cord-277665-ac8txr3h 349 22 barrier barrier NN cord-277665-ac8txr3h 349 23 transport transport NN cord-277665-ac8txr3h 349 24 of of IN cord-277665-ac8txr3h 349 25 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 349 26 Surface surface VBP cord-277665-ac8txr3h 349 27 chemistry chemistry NN cord-277665-ac8txr3h 349 28 of of IN cord-277665-ac8txr3h 349 29 nanodiamonds nanodiamonds NNP cord-277665-ac8txr3h 349 30 Chemical Chemical NNP cord-277665-ac8txr3h 349 31 properties property NNS cord-277665-ac8txr3h 349 32 of of IN cord-277665-ac8txr3h 349 33 detonation detonation NN cord-277665-ac8txr3h 349 34 - - HYPH cord-277665-ac8txr3h 349 35 synthesized synthesize VBN cord-277665-ac8txr3h 349 36 ultradispersed ultradisperse VBN cord-277665-ac8txr3h 349 37 diamond diamond NN cord-277665-ac8txr3h 349 38 Covalently covalently RB cord-277665-ac8txr3h 349 39 modified modify VBN cord-277665-ac8txr3h 349 40 silicon silicon NN cord-277665-ac8txr3h 349 41 and and CC cord-277665-ac8txr3h 349 42 diamond diamond NN cord-277665-ac8txr3h 349 43 surfaces surface NNS cord-277665-ac8txr3h 349 44 : : : cord-277665-ac8txr3h 349 45 Resistance resistance NN cord-277665-ac8txr3h 349 46 to to IN cord-277665-ac8txr3h 349 47 nonspecific nonspecific JJ cord-277665-ac8txr3h 349 48 protein protein NN cord-277665-ac8txr3h 349 49 adsorption adsorption NN cord-277665-ac8txr3h 349 50 and and CC cord-277665-ac8txr3h 349 51 optimization optimization NN cord-277665-ac8txr3h 349 52 for for IN cord-277665-ac8txr3h 349 53 biosensing biosense VBG cord-277665-ac8txr3h 349 54 Oxidation Oxidation NNP cord-277665-ac8txr3h 349 55 of of IN cord-277665-ac8txr3h 349 56 CVD CVD NNP cord-277665-ac8txr3h 349 57 diamond diamond NN cord-277665-ac8txr3h 349 58 powders powder NNS cord-277665-ac8txr3h 349 59 Reactions reaction NNS cord-277665-ac8txr3h 349 60 of of IN cord-277665-ac8txr3h 349 61 amines amine NNS cord-277665-ac8txr3h 349 62 with with IN cord-277665-ac8txr3h 349 63 CVD CVD NNP cord-277665-ac8txr3h 349 64 diamond diamond NN cord-277665-ac8txr3h 349 65 nanopowders nanopowder NNS cord-277665-ac8txr3h 349 66 Carboxyfullerene Carboxyfullerene NNP cord-277665-ac8txr3h 349 67 prevents prevent VBZ cord-277665-ac8txr3h 349 68 iron iron NN cord-277665-ac8txr3h 349 69 - - HYPH cord-277665-ac8txr3h 349 70 induced induce VBN cord-277665-ac8txr3h 349 71 oxidative oxidative JJ cord-277665-ac8txr3h 349 72 stress stress NN cord-277665-ac8txr3h 349 73 in in IN cord-277665-ac8txr3h 349 74 rat rat NN cord-277665-ac8txr3h 349 75 brain brain NN cord-277665-ac8txr3h 349 76 Advances advance VBZ cord-277665-ac8txr3h 349 77 toward toward IN cord-277665-ac8txr3h 349 78 bioapplications bioapplication NNS cord-277665-ac8txr3h 349 79 of of IN cord-277665-ac8txr3h 349 80 carbon carbon NN cord-277665-ac8txr3h 349 81 nanotubes nanotube NNS cord-277665-ac8txr3h 350 1 Paradigm paradigm NN cord-277665-ac8txr3h 350 2 shift shift NN cord-277665-ac8txr3h 350 3 in in IN cord-277665-ac8txr3h 350 4 NMDA NMDA NNP cord-277665-ac8txr3h 350 5 receptor receptor NN cord-277665-ac8txr3h 350 6 antagonist antagonist NN cord-277665-ac8txr3h 350 7 drug drug NN cord-277665-ac8txr3h 350 8 development development NN cord-277665-ac8txr3h 350 9 : : : cord-277665-ac8txr3h 351 1 Molecular molecular JJ cord-277665-ac8txr3h 351 2 mechanism mechanism NN cord-277665-ac8txr3h 351 3 of of IN cord-277665-ac8txr3h 351 4 uncompetitive uncompetitive JJ cord-277665-ac8txr3h 351 5 inhibition inhibition NN cord-277665-ac8txr3h 351 6 by by IN cord-277665-ac8txr3h 351 7 memantine memantine NNP cord-277665-ac8txr3h 351 8 in in IN cord-277665-ac8txr3h 351 9 the the DT cord-277665-ac8txr3h 351 10 treatment treatment NN cord-277665-ac8txr3h 351 11 of of IN cord-277665-ac8txr3h 351 12 Alzheimer Alzheimer NNP cord-277665-ac8txr3h 351 13 's 's POS cord-277665-ac8txr3h 351 14 disease disease NN cord-277665-ac8txr3h 351 15 and and CC cord-277665-ac8txr3h 351 16 other other JJ cord-277665-ac8txr3h 351 17 neurologic neurologic JJ cord-277665-ac8txr3h 351 18 disorders disorder NNS cord-277665-ac8txr3h 351 19 Functionalization Functionalization NNP cord-277665-ac8txr3h 351 20 of of IN cord-277665-ac8txr3h 351 21 nanoscale nanoscale JJ cord-277665-ac8txr3h 351 22 diamond diamond NN cord-277665-ac8txr3h 351 23 powder powder NN cord-277665-ac8txr3h 351 24 : : : cord-277665-ac8txr3h 351 25 Fluoro- fluoro- NN cord-277665-ac8txr3h 351 26 , , , cord-277665-ac8txr3h 351 27 alkyl- alkyl- NN cord-277665-ac8txr3h 351 28 , , , cord-277665-ac8txr3h 351 29 amino- amino- NN cord-277665-ac8txr3h 351 30 , , , cord-277665-ac8txr3h 351 31 and and CC cord-277665-ac8txr3h 351 32 amino amino NN cord-277665-ac8txr3h 351 33 acidnanodiamond acidnanodiamond NN cord-277665-ac8txr3h 352 1 derivatives derivative NNS cord-277665-ac8txr3h 352 2 Fluorinated fluorinate VBN cord-277665-ac8txr3h 352 3 nanodiamond nanodiamond NNP cord-277665-ac8txr3h 352 4 as as IN cord-277665-ac8txr3h 352 5 a a DT cord-277665-ac8txr3h 352 6 wet wet JJ cord-277665-ac8txr3h 352 7 chemistry chemistry NN cord-277665-ac8txr3h 352 8 precursor precursor NN cord-277665-ac8txr3h 352 9 for for IN cord-277665-ac8txr3h 352 10 diamond diamond NN cord-277665-ac8txr3h 352 11 coatings coating NNS cord-277665-ac8txr3h 352 12 covalently covalently RB cord-277665-ac8txr3h 352 13 bonded bond VBN cord-277665-ac8txr3h 352 14 to to IN cord-277665-ac8txr3h 352 15 glass glass NN cord-277665-ac8txr3h 352 16 surface surface NN cord-277665-ac8txr3h 352 17 Nanoparticle Nanoparticle NNP cord-277665-ac8txr3h 352 18 technology technology NN cord-277665-ac8txr3h 352 19 for for IN cord-277665-ac8txr3h 352 20 drug drug NN cord-277665-ac8txr3h 352 21 delivery delivery NN cord-277665-ac8txr3h 352 22 across across IN cord-277665-ac8txr3h 352 23 the the DT cord-277665-ac8txr3h 352 24 blood blood NN cord-277665-ac8txr3h 352 25 - - HYPH cord-277665-ac8txr3h 352 26 brain brain NN cord-277665-ac8txr3h 352 27 barrier barrier NN cord-277665-ac8txr3h 352 28 Diamond diamond NN cord-277665-ac8txr3h 352 29 and and CC cord-277665-ac8txr3h 352 30 carbon carbon NN cord-277665-ac8txr3h 352 31 nanotube nanotube NN cord-277665-ac8txr3h 352 32 glucose glucose NN cord-277665-ac8txr3h 352 33 sensors sensor NNS cord-277665-ac8txr3h 352 34 based base VBN cord-277665-ac8txr3h 352 35 on on IN cord-277665-ac8txr3h 352 36 electropolymerization electropolymerization NN cord-277665-ac8txr3h 352 37 Nanoscale Nanoscale NNP cord-277665-ac8txr3h 352 38 fluorescent fluorescent JJ cord-277665-ac8txr3h 352 39 sensors sensor NNS cord-277665-ac8txr3h 352 40 for for IN cord-277665-ac8txr3h 352 41 intracellular intracellular JJ cord-277665-ac8txr3h 352 42 analysis analysis NN cord-277665-ac8txr3h 352 43 Invasive invasive JJ cord-277665-ac8txr3h 352 44 cleavage cleavage NN cord-277665-ac8txr3h 352 45 reactions reaction NNS cord-277665-ac8txr3h 352 46 on on IN cord-277665-ac8txr3h 352 47 DNA dna NN cord-277665-ac8txr3h 352 48 - - HYPH cord-277665-ac8txr3h 352 49 modified modify VBN cord-277665-ac8txr3h 352 50 diamond diamond NN cord-277665-ac8txr3h 352 51 surfaces surface NNS cord-277665-ac8txr3h 352 52 Influence influence NN cord-277665-ac8txr3h 352 53 of of IN cord-277665-ac8txr3h 352 54 carbon carbon NN cord-277665-ac8txr3h 352 55 coatings coating NNS cord-277665-ac8txr3h 352 56 origin origin NN cord-277665-ac8txr3h 352 57 on on IN cord-277665-ac8txr3h 352 58 the the DT cord-277665-ac8txr3h 352 59 properties property NNS cord-277665-ac8txr3h 352 60 important important JJ cord-277665-ac8txr3h 352 61 for for IN cord-277665-ac8txr3h 352 62 biomedical biomedical JJ cord-277665-ac8txr3h 352 63 application application NN cord-277665-ac8txr3h 352 64 Nanocrystalline Nanocrystalline NNP cord-277665-ac8txr3h 352 65 diamond diamond NN cord-277665-ac8txr3h 352 66 coatings coating NNS cord-277665-ac8txr3h 352 67 Multi multi JJ cord-277665-ac8txr3h 352 68 - - JJ cord-277665-ac8txr3h 352 69 walled walled JJ cord-277665-ac8txr3h 352 70 carbon carbon NN cord-277665-ac8txr3h 352 71 nanotube nanotube NN cord-277665-ac8txr3h 352 72 interactions interaction NNS cord-277665-ac8txr3h 352 73 with with IN cord-277665-ac8txr3h 352 74 human human JJ cord-277665-ac8txr3h 352 75 epidermal epidermal JJ cord-277665-ac8txr3h 352 76 keratinocytes keratinocyte NNS cord-277665-ac8txr3h 352 77 Special special JJ cord-277665-ac8txr3h 352 78 features feature NNS cord-277665-ac8txr3h 352 79 of of IN cord-277665-ac8txr3h 352 80 structure structure NN cord-277665-ac8txr3h 352 81 and and CC cord-277665-ac8txr3h 352 82 physico physico NN cord-277665-ac8txr3h 352 83 - - HYPH cord-277665-ac8txr3h 352 84 mechanical mechanical JJ cord-277665-ac8txr3h 352 85 properties property NNS cord-277665-ac8txr3h 352 86 of of IN cord-277665-ac8txr3h 352 87 natural natural JJ cord-277665-ac8txr3h 352 88 diamonds diamond NNS cord-277665-ac8txr3h 352 89 of of IN cord-277665-ac8txr3h 352 90 Ukraine Ukraine NNP cord-277665-ac8txr3h 352 91 Nanoparticles Nanoparticles NNP cord-277665-ac8txr3h 352 92 , , , cord-277665-ac8txr3h 352 93 proteins protein NNS cord-277665-ac8txr3h 352 94 , , , cord-277665-ac8txr3h 352 95 and and CC cord-277665-ac8txr3h 352 96 nucleic nucleic JJ cord-277665-ac8txr3h 352 97 acids acid NNS cord-277665-ac8txr3h 353 1 : : : cord-277665-ac8txr3h 353 2 Biotechnology biotechnology NN cord-277665-ac8txr3h 353 3 meets meet VBZ cord-277665-ac8txr3h 353 4 materials material NNS cord-277665-ac8txr3h 353 5 science science NN cord-277665-ac8txr3h 353 6 Human human NN cord-277665-ac8txr3h 353 7 monocytes monocyte VBZ cord-277665-ac8txr3h 353 8 stimulation stimulation NN cord-277665-ac8txr3h 353 9 by by IN cord-277665-ac8txr3h 353 10 particles particle NNS cord-277665-ac8txr3h 353 11 of of IN cord-277665-ac8txr3h 353 12 hydroxyapatite hydroxyapatite NN cord-277665-ac8txr3h 353 13 , , , cord-277665-ac8txr3h 353 14 silicon silicon NN cord-277665-ac8txr3h 353 15 carbide carbide NN cord-277665-ac8txr3h 353 16 and and CC cord-277665-ac8txr3h 353 17 diamond diamond NN cord-277665-ac8txr3h 353 18 : : : cord-277665-ac8txr3h 354 1 In in IN cord-277665-ac8txr3h 354 2 vitro vitro FW cord-277665-ac8txr3h 354 3 studies study NNS cord-277665-ac8txr3h 354 4 of of IN cord-277665-ac8txr3h 354 5 new new JJ cord-277665-ac8txr3h 354 6 prosthesis prosthesis NN cord-277665-ac8txr3h 354 7 coatings coating NNS cord-277665-ac8txr3h 354 8 Synthesis Synthesis NNP cord-277665-ac8txr3h 354 9 and and CC cord-277665-ac8txr3h 354 10 antimicrobial antimicrobial JJ cord-277665-ac8txr3h 354 11 activity activity NN cord-277665-ac8txr3h 354 12 of of IN cord-277665-ac8txr3h 354 13 new new JJ cord-277665-ac8txr3h 354 14 adamantane adamantane NNP cord-277665-ac8txr3h 354 15 derivatives derivative NNS cord-277665-ac8txr3h 354 16 III iii CD cord-277665-ac8txr3h 354 17 Quantum Quantum NNP cord-277665-ac8txr3h 354 18 dots dot NNS cord-277665-ac8txr3h 354 19 and and CC cord-277665-ac8txr3h 354 20 other other JJ cord-277665-ac8txr3h 354 21 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 354 22 : : : cord-277665-ac8txr3h 354 23 What what WP cord-277665-ac8txr3h 354 24 can can MD cord-277665-ac8txr3h 354 25 they -PRON- PRP cord-277665-ac8txr3h 354 26 offer offer VB cord-277665-ac8txr3h 354 27 to to IN cord-277665-ac8txr3h 354 28 drug drug NN cord-277665-ac8txr3h 354 29 discovery discovery NN cord-277665-ac8txr3h 354 30 ? ? . cord-277665-ac8txr3h 355 1 Biosensing biosense VBG cord-277665-ac8txr3h 355 2 properties property NNS cord-277665-ac8txr3h 355 3 of of IN cord-277665-ac8txr3h 355 4 diamond diamond NN cord-277665-ac8txr3h 355 5 and and CC cord-277665-ac8txr3h 355 6 carbon carbon NN cord-277665-ac8txr3h 355 7 nanotubes nanotube NNS cord-277665-ac8txr3h 355 8 Electrochemical electrochemical JJ cord-277665-ac8txr3h 355 9 analysis analysis NN cord-277665-ac8txr3h 355 10 of of IN cord-277665-ac8txr3h 355 11 nucleic nucleic JJ cord-277665-ac8txr3h 355 12 acids acid NNS cord-277665-ac8txr3h 355 13 at at IN cord-277665-ac8txr3h 355 14 boron boron NN cord-277665-ac8txr3h 355 15 - - HYPH cord-277665-ac8txr3h 355 16 doped dope VBN cord-277665-ac8txr3h 355 17 diamond diamond NN cord-277665-ac8txr3h 355 18 electrodes electrode NNS cord-277665-ac8txr3h 355 19 Development Development NNP cord-277665-ac8txr3h 355 20 of of IN cord-277665-ac8txr3h 355 21 a a DT cord-277665-ac8txr3h 355 22 nonviral nonviral JJ cord-277665-ac8txr3h 355 23 gene gene NN cord-277665-ac8txr3h 355 24 delivery delivery NN cord-277665-ac8txr3h 355 25 vehicle vehicle NN cord-277665-ac8txr3h 355 26 for for IN cord-277665-ac8txr3h 355 27 systemic systemic JJ cord-277665-ac8txr3h 355 28 application application NN cord-277665-ac8txr3h 355 29 Targeted target VBN cord-277665-ac8txr3h 355 30 delivery delivery NN cord-277665-ac8txr3h 355 31 of of IN cord-277665-ac8txr3h 355 32 RNA rna NN cord-277665-ac8txr3h 355 33 - - HYPH cord-277665-ac8txr3h 355 34 cleaving cleave VBG cord-277665-ac8txr3h 355 35 DNA dna NN cord-277665-ac8txr3h 355 36 enzyme enzyme NN cord-277665-ac8txr3h 355 37 ( ( -LRB- cord-277665-ac8txr3h 355 38 DNAzyme DNAzyme NNP cord-277665-ac8txr3h 355 39 ) ) -RRB- cord-277665-ac8txr3h 355 40 to to TO cord-277665-ac8txr3h 355 41 tumor tumor VB cord-277665-ac8txr3h 355 42 tissue tissue NN cord-277665-ac8txr3h 355 43 by by IN cord-277665-ac8txr3h 355 44 transferrinmodified transferrinmodifie VBN cord-277665-ac8txr3h 355 45 , , , cord-277665-ac8txr3h 355 46 cyclodextrin cyclodextrin NN cord-277665-ac8txr3h 355 47 - - HYPH cord-277665-ac8txr3h 355 48 based base VBN cord-277665-ac8txr3h 355 49 particles particle NNS cord-277665-ac8txr3h 355 50 Damaging damage VBG cord-277665-ac8txr3h 355 51 effect effect NN cord-277665-ac8txr3h 355 52 of of IN cord-277665-ac8txr3h 355 53 detonation detonation NN cord-277665-ac8txr3h 355 54 diamonds diamond NNS cord-277665-ac8txr3h 355 55 on on IN cord-277665-ac8txr3h 355 56 human human JJ cord-277665-ac8txr3h 355 57 white white JJ cord-277665-ac8txr3h 355 58 and and CC cord-277665-ac8txr3h 355 59 red red JJ cord-277665-ac8txr3h 355 60 blood blood NN cord-277665-ac8txr3h 355 61 cells cell NNS cord-277665-ac8txr3h 355 62 in in IN cord-277665-ac8txr3h 355 63 vitro vitro FW cord-277665-ac8txr3h 355 64 Design design NN cord-277665-ac8txr3h 355 65 of of IN cord-277665-ac8txr3h 355 66 a a DT cord-277665-ac8txr3h 355 67 luminescent luminescent JJ cord-277665-ac8txr3h 355 68 biochip biochip NN cord-277665-ac8txr3h 355 69 with with IN cord-277665-ac8txr3h 355 70 nanodiamonds nanodiamond NNS cord-277665-ac8txr3h 355 71 and and CC cord-277665-ac8txr3h 355 72 bacterial bacterial JJ cord-277665-ac8txr3h 355 73 luciferase luciferase NN cord-277665-ac8txr3h 355 74 Destruction destruction NN cord-277665-ac8txr3h 355 75 of of IN cord-277665-ac8txr3h 355 76 human human JJ cord-277665-ac8txr3h 355 77 blood blood NN cord-277665-ac8txr3h 355 78 cells cell NNS cord-277665-ac8txr3h 355 79 in in IN cord-277665-ac8txr3h 355 80 interaction interaction NN cord-277665-ac8txr3h 355 81 with with IN cord-277665-ac8txr3h 355 82 detonation detonation NN cord-277665-ac8txr3h 355 83 nanodiamonds nanodiamond NNS cord-277665-ac8txr3h 355 84 in in IN cord-277665-ac8txr3h 355 85 experiments experiment NNS cord-277665-ac8txr3h 355 86 in in IN cord-277665-ac8txr3h 355 87 vitro vitro FW cord-277665-ac8txr3h 355 88 Dynamics Dynamics NNPS cord-277665-ac8txr3h 355 89 of of IN cord-277665-ac8txr3h 355 90 the the DT cord-277665-ac8txr3h 355 91 selected select VBN cord-277665-ac8txr3h 355 92 physiological physiological JJ cord-277665-ac8txr3h 355 93 responses response NNS cord-277665-ac8txr3h 355 94 in in IN cord-277665-ac8txr3h 355 95 laboratory laboratory NN cord-277665-ac8txr3h 355 96 mice mouse NNS cord-277665-ac8txr3h 355 97 under under IN cord-277665-ac8txr3h 355 98 the the DT cord-277665-ac8txr3h 355 99 prolonged prolonged JJ cord-277665-ac8txr3h 355 100 oral oral JJ cord-277665-ac8txr3h 355 101 administration administration NN cord-277665-ac8txr3h 355 102 of of IN cord-277665-ac8txr3h 355 103 nanodiamond nanodiamond NNP cord-277665-ac8txr3h 355 104 suspentions suspentions NNP cord-277665-ac8txr3h 355 105 Destruction Destruction NNP cord-277665-ac8txr3h 355 106 of of IN cord-277665-ac8txr3h 355 107 human human JJ cord-277665-ac8txr3h 355 108 blood blood NN cord-277665-ac8txr3h 355 109 cells cell NNS cord-277665-ac8txr3h 355 110 upon upon IN cord-277665-ac8txr3h 355 111 interaction interaction NN cord-277665-ac8txr3h 355 112 with with IN cord-277665-ac8txr3h 355 113 detonation detonation NN cord-277665-ac8txr3h 355 114 nanodiamonds nanodiamond NNS cord-277665-ac8txr3h 355 115 in in IN cord-277665-ac8txr3h 355 116 experiments experiment NNS cord-277665-ac8txr3h 355 117 in in IN cord-277665-ac8txr3h 355 118 vitro vitro FW cord-277665-ac8txr3h 356 1 A a DT cord-277665-ac8txr3h 356 2 possibility possibility NN cord-277665-ac8txr3h 356 3 of of IN cord-277665-ac8txr3h 356 4 using use VBG cord-277665-ac8txr3h 356 5 of of IN cord-277665-ac8txr3h 356 6 intravenous intravenous JJ cord-277665-ac8txr3h 356 7 administration administration NN cord-277665-ac8txr3h 356 8 of of IN cord-277665-ac8txr3h 356 9 sterile sterile JJ cord-277665-ac8txr3h 356 10 colloids colloid NNS cord-277665-ac8txr3h 356 11 of of IN cord-277665-ac8txr3h 356 12 modified modify VBN cord-277665-ac8txr3h 356 13 nanodiamonds nanodiamond NNS cord-277665-ac8txr3h 357 1 In in IN cord-277665-ac8txr3h 357 2 vitro vitro FW cord-277665-ac8txr3h 357 3 cytotoxicity cytotoxicity NN cord-277665-ac8txr3h 357 4 of of IN cord-277665-ac8txr3h 357 5 amorphous amorphous JJ cord-277665-ac8txr3h 357 6 carbon carbon NN cord-277665-ac8txr3h 357 7 films film NNS cord-277665-ac8txr3h 358 1 Recent recent JJ cord-277665-ac8txr3h 358 2 progress progress NN cord-277665-ac8txr3h 358 3 in in IN cord-277665-ac8txr3h 358 4 the the DT cord-277665-ac8txr3h 358 5 discovery discovery NN cord-277665-ac8txr3h 358 6 of of IN cord-277665-ac8txr3h 358 7 antagonists antagonist NNS cord-277665-ac8txr3h 358 8 acting act VBG cord-277665-ac8txr3h 358 9 at at IN cord-277665-ac8txr3h 358 10 P2X(7 P2X(7 NNP cord-277665-ac8txr3h 358 11 ) ) -RRB- cord-277665-ac8txr3h 359 1 receptor receptor NNP cord-277665-ac8txr3h 359 2 Optical optical JJ cord-277665-ac8txr3h 359 3 tracking tracking NN cord-277665-ac8txr3h 359 4 of of IN cord-277665-ac8txr3h 359 5 organically organically RB cord-277665-ac8txr3h 359 6 modified modify VBN cord-277665-ac8txr3h 359 7 silica silica NN cord-277665-ac8txr3h 359 8 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 359 9 as as IN cord-277665-ac8txr3h 359 10 DNA dna NN cord-277665-ac8txr3h 359 11 carriers carrier NNS cord-277665-ac8txr3h 359 12 : : : cord-277665-ac8txr3h 359 13 A a DT cord-277665-ac8txr3h 359 14 nonviral nonviral JJ cord-277665-ac8txr3h 359 15 , , , cord-277665-ac8txr3h 359 16 nanomedicine nanomedicine NN cord-277665-ac8txr3h 359 17 approach approach NN cord-277665-ac8txr3h 359 18 for for IN cord-277665-ac8txr3h 359 19 gene gene NN cord-277665-ac8txr3h 359 20 delivery delivery NN cord-277665-ac8txr3h 359 21 Studies Studies NNPS cord-277665-ac8txr3h 359 22 of of IN cord-277665-ac8txr3h 359 23 host host NN cord-277665-ac8txr3h 359 24 response response NN cord-277665-ac8txr3h 359 25 to to IN cord-277665-ac8txr3h 359 26 orthopedic orthopedic JJ cord-277665-ac8txr3h 359 27 implants implant NNS cord-277665-ac8txr3h 359 28 and and CC cord-277665-ac8txr3h 359 29 biomaterials biomaterial NNS cord-277665-ac8txr3h 359 30 Defects defect NNS cord-277665-ac8txr3h 359 31 and and CC cord-277665-ac8txr3h 359 32 impurities impurity NNS cord-277665-ac8txr3h 359 33 in in IN cord-277665-ac8txr3h 359 34 nanodiamonds nanodiamond NNS cord-277665-ac8txr3h 359 35 : : : cord-277665-ac8txr3h 359 36 EPR EPR NNP cord-277665-ac8txr3h 359 37 , , , cord-277665-ac8txr3h 359 38 NMR NMR NNP cord-277665-ac8txr3h 359 39 and and CC cord-277665-ac8txr3h 359 40 TEM TEM NNP cord-277665-ac8txr3h 359 41 study study NN cord-277665-ac8txr3h 359 42 Enzymes enzyme NNS cord-277665-ac8txr3h 359 43 in in IN cord-277665-ac8txr3h 359 44 the the DT cord-277665-ac8txr3h 359 45 cavity cavity NN cord-277665-ac8txr3h 359 46 of of IN cord-277665-ac8txr3h 359 47 hollow hollow JJ cord-277665-ac8txr3h 359 48 silica silica NN cord-277665-ac8txr3h 359 49 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 359 50 Carbon carbon NN cord-277665-ac8txr3h 359 51 nanostructures nanostructure NNS cord-277665-ac8txr3h 359 52 Cl Cl NNP cord-277665-ac8txr3h 359 53 - - HYPH cord-277665-ac8txr3h 359 54 sensitive sensitive JJ cord-277665-ac8txr3h 359 55 biosensor biosensor NN cord-277665-ac8txr3h 359 56 used use VBD cord-277665-ac8txr3h 359 57 electrolyte electrolyte NN cord-277665-ac8txr3h 359 58 - - HYPH cord-277665-ac8txr3h 359 59 solution solution NN cord-277665-ac8txr3h 359 60 - - HYPH cord-277665-ac8txr3h 359 61 gate gate NN cord-277665-ac8txr3h 359 62 diamond diamond NN cord-277665-ac8txr3h 359 63 FETs FETs NNP cord-277665-ac8txr3h 359 64 Surface surface NN cord-277665-ac8txr3h 359 65 - - HYPH cord-277665-ac8txr3h 359 66 modified modify VBN cord-277665-ac8txr3h 359 67 diamond diamond NN cord-277665-ac8txr3h 359 68 field field NN cord-277665-ac8txr3h 359 69 - - HYPH cord-277665-ac8txr3h 359 70 effect effect NN cord-277665-ac8txr3h 359 71 transistors transistor NNS cord-277665-ac8txr3h 359 72 for for IN cord-277665-ac8txr3h 359 73 enzyme enzyme NN cord-277665-ac8txr3h 359 74 - - HYPH cord-277665-ac8txr3h 359 75 immobilized immobilize VBN cord-277665-ac8txr3h 359 76 biosensors biosensor NNS cord-277665-ac8txr3h 359 77 Dementia Dementia NNP cord-277665-ac8txr3h 359 78 of of IN cord-277665-ac8txr3h 359 79 Alzheimer Alzheimer NNP cord-277665-ac8txr3h 359 80 's 's POS cord-277665-ac8txr3h 359 81 disease disease NN cord-277665-ac8txr3h 359 82 and and CC cord-277665-ac8txr3h 359 83 other other JJ cord-277665-ac8txr3h 359 84 neurodegenerative neurodegenerative JJ cord-277665-ac8txr3h 359 85 disorders disorder NNS cord-277665-ac8txr3h 359 86 - - : cord-277665-ac8txr3h 359 87 Memantine Memantine NNP cord-277665-ac8txr3h 359 88 , , , cord-277665-ac8txr3h 359 89 a a DT cord-277665-ac8txr3h 359 90 new new JJ cord-277665-ac8txr3h 359 91 hope hope NN cord-277665-ac8txr3h 359 92 Effect effect NN cord-277665-ac8txr3h 359 93 of of IN cord-277665-ac8txr3h 359 94 treatment treatment NN cord-277665-ac8txr3h 359 95 temperature temperature NN cord-277665-ac8txr3h 359 96 on on IN cord-277665-ac8txr3h 359 97 the the DT cord-277665-ac8txr3h 359 98 amination amination NN cord-277665-ac8txr3h 359 99 of of IN cord-277665-ac8txr3h 359 100 chlorinated chlorinated JJ cord-277665-ac8txr3h 359 101 diamond diamond NN cord-277665-ac8txr3h 359 102 Ordered order VBN cord-277665-ac8txr3h 359 103 growth growth NN cord-277665-ac8txr3h 359 104 of of IN cord-277665-ac8txr3h 359 105 neurons neuron NNS cord-277665-ac8txr3h 359 106 on on IN cord-277665-ac8txr3h 359 107 diamond diamond NN cord-277665-ac8txr3h 359 108 Purification purification NN cord-277665-ac8txr3h 359 109 and and CC cord-277665-ac8txr3h 359 110 modification modification NN cord-277665-ac8txr3h 359 111 of of IN cord-277665-ac8txr3h 359 112 nanodiamond nanodiamond JJ cord-277665-ac8txr3h 359 113 New New NNP cord-277665-ac8txr3h 359 114 amperometric amperometric JJ cord-277665-ac8txr3h 359 115 biosensors biosensor NNS cord-277665-ac8txr3h 359 116 based base VBN cord-277665-ac8txr3h 359 117 on on IN cord-277665-ac8txr3h 359 118 diamond diamond NN cord-277665-ac8txr3h 359 119 paste paste NN cord-277665-ac8txr3h 359 120 for for IN cord-277665-ac8txr3h 359 121 the the DT cord-277665-ac8txr3h 359 122 assay assay NN cord-277665-ac8txr3h 359 123 of of IN cord-277665-ac8txr3h 359 124 L l NN cord-277665-ac8txr3h 359 125 - - : cord-277665-ac8txr3h 359 126 and and CC cord-277665-ac8txr3h 359 127 D D NNP cord-277665-ac8txr3h 359 128 - - HYPH cord-277665-ac8txr3h 359 129 pipecolic pipecolic JJ cord-277665-ac8txr3h 359 130 acids acid NNS cord-277665-ac8txr3h 359 131 in in IN cord-277665-ac8txr3h 359 132 serum serum NN cord-277665-ac8txr3h 359 133 samples sample NNS cord-277665-ac8txr3h 359 134 Surface surface NN cord-277665-ac8txr3h 359 135 transfer transfer NN cord-277665-ac8txr3h 359 136 doping doping NN cord-277665-ac8txr3h 359 137 of of IN cord-277665-ac8txr3h 359 138 diamond diamond NN cord-277665-ac8txr3h 359 139 Photochemical photochemical JJ cord-277665-ac8txr3h 359 140 functionalization functionalization NN cord-277665-ac8txr3h 359 141 of of IN cord-277665-ac8txr3h 359 142 diamond diamond NN cord-277665-ac8txr3h 359 143 films film NNS cord-277665-ac8txr3h 360 1 A a DT cord-277665-ac8txr3h 360 2 comparison comparison NN cord-277665-ac8txr3h 360 3 of of IN cord-277665-ac8txr3h 360 4 the the DT cord-277665-ac8txr3h 360 5 effects effect NNS cord-277665-ac8txr3h 360 6 of of IN cord-277665-ac8txr3h 360 7 urate urate NN cord-277665-ac8txr3h 360 8 , , , cord-277665-ac8txr3h 360 9 hydroxyapatite hydroxyapatite NN cord-277665-ac8txr3h 360 10 and and CC cord-277665-ac8txr3h 360 11 diamond diamond NN cord-277665-ac8txr3h 360 12 crystals crystal NNS cord-277665-ac8txr3h 360 13 on on IN cord-277665-ac8txr3h 360 14 polymorphonuclear polymorphonuclear JJ cord-277665-ac8txr3h 360 15 cells cell NNS cord-277665-ac8txr3h 360 16 - - : cord-277665-ac8txr3h 360 17 Relationship relationship NN cord-277665-ac8txr3h 360 18 of of IN cord-277665-ac8txr3h 360 19 mediator mediator NN cord-277665-ac8txr3h 360 20 release release NN cord-277665-ac8txr3h 360 21 to to IN cord-277665-ac8txr3h 360 22 the the DT cord-277665-ac8txr3h 360 23 surface surface NN cord-277665-ac8txr3h 360 24 - - HYPH cord-277665-ac8txr3h 360 25 area area NN cord-277665-ac8txr3h 360 26 and and CC cord-277665-ac8txr3h 360 27 adsorptive adsorptive JJ cord-277665-ac8txr3h 360 28 capacity capacity NN cord-277665-ac8txr3h 360 29 of of IN cord-277665-ac8txr3h 360 30 different different JJ cord-277665-ac8txr3h 360 31 particles particle NNS cord-277665-ac8txr3h 360 32 Diamond diamond NN cord-277665-ac8txr3h 360 33 nanofabrication nanofabrication NN cord-277665-ac8txr3h 360 34 and and CC cord-277665-ac8txr3h 360 35 characterization characterization NN cord-277665-ac8txr3h 360 36 for for IN cord-277665-ac8txr3h 360 37 biosensing biosense VBG cord-277665-ac8txr3h 360 38 application application NN cord-277665-ac8txr3h 360 39 Biocompatibility Biocompatibility NNP cord-277665-ac8txr3h 360 40 of of IN cord-277665-ac8txr3h 360 41 chemical chemical NN cord-277665-ac8txr3h 360 42 - - HYPH cord-277665-ac8txr3h 360 43 vapor vapor NN cord-277665-ac8txr3h 360 44 - - HYPH cord-277665-ac8txr3h 360 45 deposited deposit VBN cord-277665-ac8txr3h 360 46 diamond diamond NN cord-277665-ac8txr3h 361 1 The the DT cord-277665-ac8txr3h 361 2 adamantane adamantane NN cord-277665-ac8txr3h 361 3 - - HYPH cord-277665-ac8txr3h 361 4 derived derive VBN cord-277665-ac8txr3h 361 5 bananins bananin NNS cord-277665-ac8txr3h 361 6 are be VBP cord-277665-ac8txr3h 361 7 potent potent JJ cord-277665-ac8txr3h 361 8 inhibitors inhibitor NNS cord-277665-ac8txr3h 361 9 of of IN cord-277665-ac8txr3h 361 10 the the DT cord-277665-ac8txr3h 361 11 helicase helicase NN cord-277665-ac8txr3h 361 12 activities activity NNS cord-277665-ac8txr3h 361 13 and and CC cord-277665-ac8txr3h 361 14 replication replication NN cord-277665-ac8txr3h 361 15 of of IN cord-277665-ac8txr3h 361 16 SARS SARS NNP cord-277665-ac8txr3h 361 17 coronavirus coronavirus NN cord-277665-ac8txr3h 361 18 Electron Electron NNP cord-277665-ac8txr3h 361 19 transfer transfer NN cord-277665-ac8txr3h 361 20 from from IN cord-277665-ac8txr3h 361 21 diamond diamond NN cord-277665-ac8txr3h 361 22 electrodes electrode NNS cord-277665-ac8txr3h 361 23 to to IN cord-277665-ac8txr3h 361 24 heme heme NN cord-277665-ac8txr3h 361 25 peptide peptide NN cord-277665-ac8txr3h 361 26 and and CC cord-277665-ac8txr3h 361 27 peroxidase peroxidase VBD cord-277665-ac8txr3h 361 28 Biocompatibility Biocompatibility NNP cord-277665-ac8txr3h 361 29 of of IN cord-277665-ac8txr3h 361 30 diamondlike diamondlike JJ cord-277665-ac8txr3h 361 31 carbon carbon NN cord-277665-ac8txr3h 361 32 coating coating NN cord-277665-ac8txr3h 361 33 Diamond Diamond NNP cord-277665-ac8txr3h 361 34 - - HYPH cord-277665-ac8txr3h 361 35 based base VBN cord-277665-ac8txr3h 361 36 glucose glucose NN cord-277665-ac8txr3h 361 37 sensors sensor NNS cord-277665-ac8txr3h 361 38 Polymorphonuclear polymorphonuclear JJ cord-277665-ac8txr3h 361 39 leukocyte leukocyte NN cord-277665-ac8txr3h 361 40 motility motility NN cord-277665-ac8txr3h 361 41 in in IN cord-277665-ac8txr3h 361 42 - - HYPH cord-277665-ac8txr3h 361 43 vitro vitro FW cord-277665-ac8txr3h 361 44 . . . cord-277665-ac8txr3h 362 1 5 5 LS cord-277665-ac8txr3h 362 2 . . . cord-277665-ac8txr3h 363 1 Release release NN cord-277665-ac8txr3h 363 2 of of IN cord-277665-ac8txr3h 363 3 chemotactic chemotactic JJ cord-277665-ac8txr3h 363 4 activity activity NN cord-277665-ac8txr3h 363 5 following follow VBG cord-277665-ac8txr3h 363 6 phagocytosis phagocytosis NN cord-277665-ac8txr3h 363 7 of of IN cord-277665-ac8txr3h 363 8 calcium calcium NN cord-277665-ac8txr3h 363 9 pyrophosphate pyrophosphate NN cord-277665-ac8txr3h 363 10 crystals crystal NNS cord-277665-ac8txr3h 363 11 , , , cord-277665-ac8txr3h 363 12 diamond diamond NN cord-277665-ac8txr3h 363 13 dust dust NN cord-277665-ac8txr3h 363 14 , , , cord-277665-ac8txr3h 363 15 and and CC cord-277665-ac8txr3h 363 16 urate urate NN cord-277665-ac8txr3h 363 17 crystals crystal NNS cord-277665-ac8txr3h 363 18 Abstraction abstraction NN cord-277665-ac8txr3h 363 19 of of IN cord-277665-ac8txr3h 363 20 hydrogen hydrogen NN cord-277665-ac8txr3h 363 21 atoms atom NNS cord-277665-ac8txr3h 363 22 on on IN cord-277665-ac8txr3h 363 23 diamond diamond NN cord-277665-ac8txr3h 363 24 surface surface NN cord-277665-ac8txr3h 363 25 using use VBG cord-277665-ac8txr3h 363 26 benzoyl benzoyl NN cord-277665-ac8txr3h 363 27 peroxide peroxide NN cord-277665-ac8txr3h 363 28 as as IN cord-277665-ac8txr3h 363 29 a a DT cord-277665-ac8txr3h 363 30 radical radical JJ cord-277665-ac8txr3h 363 31 initiator initiator NN cord-277665-ac8txr3h 363 32 Surface surface NN cord-277665-ac8txr3h 363 33 reforming reform VBG cord-277665-ac8txr3h 363 34 of of IN cord-277665-ac8txr3h 363 35 the the DT cord-277665-ac8txr3h 363 36 oxidized oxidize VBN cord-277665-ac8txr3h 363 37 diamond diamond NN cord-277665-ac8txr3h 363 38 surface surface NN cord-277665-ac8txr3h 363 39 with with IN cord-277665-ac8txr3h 363 40 silane silane NN cord-277665-ac8txr3h 363 41 coupling couple VBG cord-277665-ac8txr3h 363 42 reagents reagent NNS cord-277665-ac8txr3h 363 43 Chemical chemical NN cord-277665-ac8txr3h 363 44 modification modification NN cord-277665-ac8txr3h 363 45 of of IN cord-277665-ac8txr3h 363 46 diamond diamond NN cord-277665-ac8txr3h 363 47 surface surface NN cord-277665-ac8txr3h 363 48 with with IN cord-277665-ac8txr3h 363 49 various various JJ cord-277665-ac8txr3h 363 50 carboxylic carboxylic JJ cord-277665-ac8txr3h 363 51 acids acid NNS cord-277665-ac8txr3h 363 52 by by IN cord-277665-ac8txr3h 363 53 radical radical JJ cord-277665-ac8txr3h 363 54 reaction reaction NN cord-277665-ac8txr3h 363 55 in in IN cord-277665-ac8txr3h 363 56 liquid liquid NN cord-277665-ac8txr3h 363 57 phase phase NN cord-277665-ac8txr3h 363 58 Covalent covalent JJ cord-277665-ac8txr3h 363 59 immobilization immobilization NN cord-277665-ac8txr3h 363 60 of of IN cord-277665-ac8txr3h 363 61 DNA dna NN cord-277665-ac8txr3h 363 62 on on IN cord-277665-ac8txr3h 363 63 diamond diamond NN cord-277665-ac8txr3h 363 64 and and CC cord-277665-ac8txr3h 363 65 its -PRON- PRP$ cord-277665-ac8txr3h 363 66 verification verification NN cord-277665-ac8txr3h 363 67 by by IN cord-277665-ac8txr3h 363 68 diffuse diffuse JJ cord-277665-ac8txr3h 363 69 reflectance reflectance NN cord-277665-ac8txr3h 363 70 infrared infrared JJ cord-277665-ac8txr3h 363 71 spectroscopy spectroscopy NN cord-277665-ac8txr3h 363 72 Structure Structure NNP cord-277665-ac8txr3h 363 73 of of IN cord-277665-ac8txr3h 363 74 detonation detonation NN cord-277665-ac8txr3h 363 75 diamond diamond NN cord-277665-ac8txr3h 363 76 nanoparticles nanoparticle NNS cord-277665-ac8txr3h 363 77 Nanosensors Nanosensors NNP cord-277665-ac8txr3h 363 78 and and CC cord-277665-ac8txr3h 363 79 biochips biochip NNS cord-277665-ac8txr3h 363 80 : : : cord-277665-ac8txr3h 363 81 Frontiers frontier NNS cord-277665-ac8txr3h 363 82 in in IN cord-277665-ac8txr3h 363 83 biomolecular biomolecular JJ cord-277665-ac8txr3h 363 84 diagnostics diagnostic NNS cord-277665-ac8txr3h 364 1 In in IN cord-277665-ac8txr3h 364 2 vitro vitro FW cord-277665-ac8txr3h 364 3 and and CC cord-277665-ac8txr3h 364 4 in in IN cord-277665-ac8txr3h 364 5 vivo vivo NN cord-277665-ac8txr3h 364 6 growth growth NN cord-277665-ac8txr3h 364 7 inhibition inhibition NN cord-277665-ac8txr3h 364 8 of of IN cord-277665-ac8txr3h 364 9 cancer cancer NN cord-277665-ac8txr3h 364 10 cells cell NNS cord-277665-ac8txr3h 364 11 by by IN cord-277665-ac8txr3h 364 12 adamantylmaleimide adamantylmaleimide JJ cord-277665-ac8txr3h 364 13 derivatives derivative NNS cord-277665-ac8txr3h 365 1 Nucleic nucleic JJ cord-277665-ac8txr3h 365 2 acid acid NN cord-277665-ac8txr3h 365 3 nanotechnology nanotechnology NN cord-277665-ac8txr3h 366 1 -Towards -Towards . cord-277665-ac8txr3h 367 1 Angstrom angstrom JJ cord-277665-ac8txr3h 367 2 - - HYPH cord-277665-ac8txr3h 367 3 scale scale NN cord-277665-ac8txr3h 367 4 engineering engineering NN cord-277665-ac8txr3h 367 5 Covalent covalent JJ cord-277665-ac8txr3h 367 6 immobilization immobilization NN cord-277665-ac8txr3h 367 7 of of IN cord-277665-ac8txr3h 367 8 DNA dna NN cord-277665-ac8txr3h 367 9 on on IN cord-277665-ac8txr3h 367 10 CVD CVD NNP cord-277665-ac8txr3h 367 11 diamond diamond NN cord-277665-ac8txr3h 367 12 films film NNS cord-277665-ac8txr3h 367 13 Biological biological JJ cord-277665-ac8txr3h 367 14 aspects aspect NNS cord-277665-ac8txr3h 367 15 of of IN cord-277665-ac8txr3h 367 16 fullerenes fullerene NNS cord-277665-ac8txr3h 368 1 A a DT cord-277665-ac8txr3h 368 2 new new JJ cord-277665-ac8txr3h 368 3 method method NN cord-277665-ac8txr3h 368 4 for for IN cord-277665-ac8txr3h 368 5 deaggregation deaggregation NN cord-277665-ac8txr3h 368 6 of of IN cord-277665-ac8txr3h 368 7 nanodiamond nanodiamond NNP cord-277665-ac8txr3h 368 8 from from IN cord-277665-ac8txr3h 368 9 explosive explosive JJ cord-277665-ac8txr3h 368 10 detonation detonation NN cord-277665-ac8txr3h 368 11 : : : cord-277665-ac8txr3h 368 12 Graphitization graphitization NN cord-277665-ac8txr3h 368 13 - - HYPH cord-277665-ac8txr3h 368 14 oxidation oxidation NN cord-277665-ac8txr3h 368 15 method method NN cord-277665-ac8txr3h 368 16 Dispersion dispersion NN cord-277665-ac8txr3h 368 17 and and CC cord-277665-ac8txr3h 368 18 stability stability NN cord-277665-ac8txr3h 368 19 of of IN cord-277665-ac8txr3h 368 20 nanodiamond nanodiamond NNP cord-277665-ac8txr3h 368 21 in in IN cord-277665-ac8txr3h 368 22 clean clean JJ cord-277665-ac8txr3h 368 23 oil oil NN cord-277665-ac8txr3h 368 24 Effect effect NN cord-277665-ac8txr3h 368 25 of of IN cord-277665-ac8txr3h 368 26 sodium sodium NN cord-277665-ac8txr3h 368 27 oleate oleate NN cord-277665-ac8txr3h 368 28 adsorption adsorption NN cord-277665-ac8txr3h 368 29 on on IN cord-277665-ac8txr3h 368 30 the the DT cord-277665-ac8txr3h 368 31 colloidal colloidal NN cord-277665-ac8txr3h 368 32 stability stability NN cord-277665-ac8txr3h 368 33 and and CC cord-277665-ac8txr3h 368 34 zeta zeta NN cord-277665-ac8txr3h 368 35 potential potential NN cord-277665-ac8txr3h 368 36 of of IN cord-277665-ac8txr3h 368 37 detonation detonation NN cord-277665-ac8txr3h 368 38 synthesized synthesize VBN cord-277665-ac8txr3h 368 39 diamond diamond NN cord-277665-ac8txr3h 368 40 particles particle NNS cord-277665-ac8txr3h 368 41 in in IN cord-277665-ac8txr3h 368 42 aqueous aqueous JJ cord-277665-ac8txr3h 368 43 solutions solution NNS cord-277665-ac8txr3h 368 44 Mechanochemical Mechanochemical NNP cord-277665-ac8txr3h 368 45 dispersion dispersion NN cord-277665-ac8txr3h 368 46 of of IN cord-277665-ac8txr3h 368 47 nanodiamond nanodiamond NNP cord-277665-ac8txr3h 368 48 aggregates aggregate NNS cord-277665-ac8txr3h 368 49 in in IN cord-277665-ac8txr3h 368 50 aqueous aqueous JJ cord-277665-ac8txr3h 368 51 media medium NNS cord-277665-ac8txr3h 368 52 Influence influence NN cord-277665-ac8txr3h 368 53 of of IN cord-277665-ac8txr3h 368 54 surface surface NN cord-277665-ac8txr3h 368 55 modification modification NN cord-277665-ac8txr3h 368 56 adopting adopt VBG cord-277665-ac8txr3h 368 57 thermal thermal JJ cord-277665-ac8txr3h 368 58 treatments treatment NNS cord-277665-ac8txr3h 368 59 on on IN cord-277665-ac8txr3h 368 60 dispersion dispersion NN cord-277665-ac8txr3h 368 61 of of IN cord-277665-ac8txr3h 368 62 detonation detonation NN cord-277665-ac8txr3h 368 63 nanodiamond nanodiamond NNP cord-277665-ac8txr3h 368 64 Fabrication Fabrication NNP cord-277665-ac8txr3h 368 65 and and CC cord-277665-ac8txr3h 368 66 characterization characterization NN cord-277665-ac8txr3h 368 67 of of IN cord-277665-ac8txr3h 368 68 a a DT cord-277665-ac8txr3h 368 69 biologically biologically RB cord-277665-ac8txr3h 368 70 sensitive sensitive JJ cord-277665-ac8txr3h 368 71 field field NN cord-277665-ac8txr3h 368 72 - - HYPH cord-277665-ac8txr3h 368 73 effect effect NN cord-277665-ac8txr3h 368 74 transistor transistor NN cord-277665-ac8txr3h 368 75 using use VBG cord-277665-ac8txr3h 368 76 a a DT cord-277665-ac8txr3h 368 77 nanocrystalline nanocrystalline NNP cord-277665-ac8txr3h 368 78 diamond diamond NN cord-277665-ac8txr3h 368 79 thin thin JJ cord-277665-ac8txr3h 368 80 film film NN cord-277665-ac8txr3h 368 81 DNA dna NN cord-277665-ac8txr3h 368 82 - - HYPH cord-277665-ac8txr3h 368 83 modified modify VBN cord-277665-ac8txr3h 368 84 nanocrystalline nanocrystalline NN cord-277665-ac8txr3h 368 85 diamond diamond NN cord-277665-ac8txr3h 368 86 thin thin JJ cord-277665-ac8txr3h 368 87 - - HYPH cord-277665-ac8txr3h 368 88 films film NNS cord-277665-ac8txr3h 368 89 as as IN cord-277665-ac8txr3h 368 90 stable stable JJ cord-277665-ac8txr3h 368 91 , , , cord-277665-ac8txr3h 368 92 biologically biologically RB cord-277665-ac8txr3h 368 93 active active JJ cord-277665-ac8txr3h 368 94 substrates substrate NNS cord-277665-ac8txr3h 369 1 Interfacial interfacial JJ cord-277665-ac8txr3h 369 2 electrical electrical JJ cord-277665-ac8txr3h 369 3 properties property NNS cord-277665-ac8txr3h 369 4 of of IN cord-277665-ac8txr3h 369 5 DNA dna NN cord-277665-ac8txr3h 369 6 - - HYPH cord-277665-ac8txr3h 369 7 modified modify VBN cord-277665-ac8txr3h 369 8 diamond diamond NN cord-277665-ac8txr3h 369 9 thin thin JJ cord-277665-ac8txr3h 369 10 films film NNS cord-277665-ac8txr3h 369 11 : : : cord-277665-ac8txr3h 370 1 Intrinsic intrinsic JJ cord-277665-ac8txr3h 370 2 response response NN cord-277665-ac8txr3h 370 3 and and CC cord-277665-ac8txr3h 370 4 hybridization hybridization NN cord-277665-ac8txr3h 370 5 - - HYPH cord-277665-ac8txr3h 370 6 induced induce VBN cord-277665-ac8txr3h 370 7 field field NN cord-277665-ac8txr3h 370 8 effects effect NNS cord-277665-ac8txr3h 370 9 Electrically electrically RB cord-277665-ac8txr3h 370 10 addressable addressable JJ cord-277665-ac8txr3h 370 11 biomolecular biomolecular JJ cord-277665-ac8txr3h 370 12 functionalization functionalization NN cord-277665-ac8txr3h 370 13 of of IN cord-277665-ac8txr3h 370 14 conductive conductive JJ cord-277665-ac8txr3h 370 15 nanocrystalline nanocrystalline NNP cord-277665-ac8txr3h 370 16 diamond diamond NNP cord-277665-ac8txr3h 370 17 thin thin JJ cord-277665-ac8txr3h 370 18 films film NNS cord-277665-ac8txr3h 371 1 Structural structural JJ cord-277665-ac8txr3h 371 2 study study NN cord-277665-ac8txr3h 371 3 of of IN cord-277665-ac8txr3h 371 4 detonation detonation NN cord-277665-ac8txr3h 371 5 nanodiamonds nanodiamonds NNP cord-277665-ac8txr3h 371 6 MPACVD MPACVD NNP cord-277665-ac8txr3h 371 7 nanocrystalline nanocrystalline NNP cord-277665-ac8txr3h 371 8 diamond diamond NN cord-277665-ac8txr3h 371 9 for for IN cord-277665-ac8txr3h 371 10 biomedical biomedical JJ cord-277665-ac8txr3h 371 11 applications application NNS cord-277665-ac8txr3h 371 12 . . . cord-277665-ac8txr3h 372 1 High high JJ cord-277665-ac8txr3h 372 2 Performance Performance NNP cord-277665-ac8txr3h 372 3 Ceram Ceram NNP cord-277665-ac8txr3h 372 4 Chemical Chemical NNP cord-277665-ac8txr3h 372 5 mechanical mechanical JJ cord-277665-ac8txr3h 372 6 modification modification NN cord-277665-ac8txr3h 372 7 of of IN cord-277665-ac8txr3h 372 8 nanodiamond nanodiamond NN cord-277665-ac8txr3h 372 9 in in IN cord-277665-ac8txr3h 372 10 an an DT cord-277665-ac8txr3h 372 11 aqueous aqueous JJ cord-277665-ac8txr3h 372 12 system system NN