id	sid	tid	token	lemma	pos
cord-015935-r2wd1yfa	1	1	key	key	JJ
cord-015935-r2wd1yfa	1	2	:	:	:
cord-015935-r2wd1yfa	1	3	cord-015935-r2wd1yfa	cord-015935-r2wd1yfa	NN
cord-015935-r2wd1yfa	1	4	authors	author	NNS
cord-015935-r2wd1yfa	1	5	:	:	:
cord-015935-r2wd1yfa	1	6	Sokol	Sokol	NNP
cord-015935-r2wd1yfa	1	7	,	,	,
cord-015935-r2wd1yfa	1	8	Deborah	Deborah	NNP
cord-015935-r2wd1yfa	1	9	K.	K.	NNP
cord-015935-r2wd1yfa	1	10	;	;	:
cord-015935-r2wd1yfa	1	11	Lahiri	Lahiri	NNP
cord-015935-r2wd1yfa	1	12	,	,	,
cord-015935-r2wd1yfa	1	13	Debomoy	Debomoy	NNP
cord-015935-r2wd1yfa	1	14	K.	K.	NNP
cord-015935-r2wd1yfa	1	15	title	title	NN
cord-015935-r2wd1yfa	1	16	:	:	:
cord-015935-r2wd1yfa	1	17	The	the	DT
cord-015935-r2wd1yfa	1	18	Genetics	Genetics	NNP
cord-015935-r2wd1yfa	1	19	of	of	IN
cord-015935-r2wd1yfa	1	20	Autism	Autism	NNP
cord-015935-r2wd1yfa	1	21	date	date	NN
cord-015935-r2wd1yfa	1	22	:	:	:
cord-015935-r2wd1yfa	1	23	2011	2011	CD
cord-015935-r2wd1yfa	1	24	-	-	SYM
cord-015935-r2wd1yfa	1	25	02	02	CD
cord-015935-r2wd1yfa	1	26	-	-	SYM
cord-015935-r2wd1yfa	1	27	10	10	CD
cord-015935-r2wd1yfa	1	28	journal	journal	NN
cord-015935-r2wd1yfa	1	29	:	:	:
cord-015935-r2wd1yfa	1	30	International	International	NNP
cord-015935-r2wd1yfa	1	31	Handbook	Handbook	NNP
cord-015935-r2wd1yfa	1	32	of	of	IN
cord-015935-r2wd1yfa	1	33	Autism	Autism	NNP
cord-015935-r2wd1yfa	1	34	and	and	CC
cord-015935-r2wd1yfa	1	35	Pervasive	Pervasive	NNP
cord-015935-r2wd1yfa	1	36	Developmental	Developmental	NNP
cord-015935-r2wd1yfa	1	37	Disorders	Disorders	NNPS
cord-015935-r2wd1yfa	1	38	DOI	doi	NN
cord-015935-r2wd1yfa	1	39	:	:	:
cord-015935-r2wd1yfa	1	40	10.1007/978	10.1007/978	CD
cord-015935-r2wd1yfa	1	41	-	-	HYPH
cord-015935-r2wd1yfa	1	42	1	1	CD
cord-015935-r2wd1yfa	1	43	-	-	HYPH
cord-015935-r2wd1yfa	1	44	4419	4419	CD
cord-015935-r2wd1yfa	1	45	-	-	HYPH
cord-015935-r2wd1yfa	1	46	8065	8065	CD
cord-015935-r2wd1yfa	2	1	-6_6	-6_6	.
cord-015935-r2wd1yfa	3	1	sha	sha	NNP
cord-015935-r2wd1yfa	3	2	:	:	:
cord-015935-r2wd1yfa	3	3	2706bb9d4f3806e6f1bbd18849aa021d223d234b	2706bb9d4f3806e6f1bbd18849aa021d223d234b	NNP
cord-015935-r2wd1yfa	3	4	doc_id	doc_id	CD
cord-015935-r2wd1yfa	3	5	:	:	:
cord-015935-r2wd1yfa	3	6	15935	15935	CD
cord-015935-r2wd1yfa	3	7	cord_uid	cord_uid	NNS
cord-015935-r2wd1yfa	3	8	:	:	:
cord-015935-r2wd1yfa	4	1	r2wd1yfa	r2wd1yfa	XX
cord-015935-r2wd1yfa	4	2	This	this	DT
cord-015935-r2wd1yfa	4	3	chapter	chapter	NN
cord-015935-r2wd1yfa	4	4	is	be	VBZ
cord-015935-r2wd1yfa	4	5	written	write	VBN
cord-015935-r2wd1yfa	4	6	to	to	TO
cord-015935-r2wd1yfa	4	7	make	make	VB
cord-015935-r2wd1yfa	4	8	the	the	DT
cord-015935-r2wd1yfa	4	9	fast	fast	RB
cord-015935-r2wd1yfa	4	10	-	-	HYPH
cord-015935-r2wd1yfa	4	11	paced	pace	VBN
cord-015935-r2wd1yfa	4	12	,	,	,
cord-015935-r2wd1yfa	4	13	expanding	expand	VBG
cord-015935-r2wd1yfa	4	14	field	field	NN
cord-015935-r2wd1yfa	4	15	of	of	IN
cord-015935-r2wd1yfa	4	16	the	the	DT
cord-015935-r2wd1yfa	4	17	genetics	genetic	NNS
cord-015935-r2wd1yfa	4	18	of	of	IN
cord-015935-r2wd1yfa	4	19	autism	autism	NN
cord-015935-r2wd1yfa	4	20	accessible	accessible	JJ
cord-015935-r2wd1yfa	4	21	to	to	IN
cord-015935-r2wd1yfa	4	22	those	those	DT
cord-015935-r2wd1yfa	4	23	practitioners	practitioner	NNS
cord-015935-r2wd1yfa	4	24	who	who	WP
cord-015935-r2wd1yfa	4	25	help	help	VBP
cord-015935-r2wd1yfa	4	26	children	child	NNS
cord-015935-r2wd1yfa	4	27	with	with	IN
cord-015935-r2wd1yfa	4	28	autism	autism	NN
cord-015935-r2wd1yfa	4	29	.	.	.
cord-015935-r2wd1yfa	5	1	New	new	JJ
cord-015935-r2wd1yfa	5	2	genetic	genetic	JJ
cord-015935-r2wd1yfa	5	3	knowledge	knowledge	NN
cord-015935-r2wd1yfa	5	4	and	and	CC
cord-015935-r2wd1yfa	5	5	technology	technology	NN
cord-015935-r2wd1yfa	5	6	have	have	VBP
cord-015935-r2wd1yfa	5	7	quickly	quickly	RB
cord-015935-r2wd1yfa	5	8	developed	develop	VBN
cord-015935-r2wd1yfa	5	9	over	over	IN
cord-015935-r2wd1yfa	5	10	the	the	DT
cord-015935-r2wd1yfa	5	11	past	past	JJ
cord-015935-r2wd1yfa	5	12	30	30	CD
cord-015935-r2wd1yfa	5	13	years	year	NNS
cord-015935-r2wd1yfa	5	14	,	,	,
cord-015935-r2wd1yfa	5	15	particularly	particularly	RB
cord-015935-r2wd1yfa	5	16	within	within	IN
cord-015935-r2wd1yfa	5	17	the	the	DT
cord-015935-r2wd1yfa	5	18	past	past	JJ
cord-015935-r2wd1yfa	5	19	decade	decade	NN
cord-015935-r2wd1yfa	5	20	,	,	,
cord-015935-r2wd1yfa	5	21	and	and	CC
cord-015935-r2wd1yfa	5	22	have	have	VBP
cord-015935-r2wd1yfa	5	23	made	make	VBN
cord-015935-r2wd1yfa	5	24	many	many	JJ
cord-015935-r2wd1yfa	5	25	optimistic	optimistic	JJ
cord-015935-r2wd1yfa	5	26	about	about	IN
cord-015935-r2wd1yfa	5	27	our	-PRON-	PRP$
cord-015935-r2wd1yfa	5	28	ability	ability	NN
cord-015935-r2wd1yfa	5	29	to	to	TO
cord-015935-r2wd1yfa	5	30	explain	explain	VB
cord-015935-r2wd1yfa	5	31	autism	autism	NN
cord-015935-r2wd1yfa	5	32	.	.	.
cord-015935-r2wd1yfa	6	1	Among	among	IN
cord-015935-r2wd1yfa	6	2	these	these	DT
cord-015935-r2wd1yfa	6	3	advances	advance	NNS
cord-015935-r2wd1yfa	6	4	include	include	VBP
cord-015935-r2wd1yfa	6	5	the	the	DT
cord-015935-r2wd1yfa	6	6	sequencing	sequencing	NN
cord-015935-r2wd1yfa	6	7	of	of	IN
cord-015935-r2wd1yfa	6	8	the	the	DT
cord-015935-r2wd1yfa	6	9	human	human	JJ
cord-015935-r2wd1yfa	6	10	genome	genome	NN
cord-015935-r2wd1yfa	6	11	(	(	-LRB-
cord-015935-r2wd1yfa	6	12	Lander	Lander	NNP
cord-015935-r2wd1yfa	6	13	et	et	NNP
cord-015935-r2wd1yfa	6	14	al	al	NNP
cord-015935-r2wd1yfa	6	15	.	.	NNP
cord-015935-r2wd1yfa	6	16	,	,	,
cord-015935-r2wd1yfa	6	17	2001	2001	CD
cord-015935-r2wd1yfa	6	18	)	)	-RRB-
cord-015935-r2wd1yfa	6	19	and	and	CC
cord-015935-r2wd1yfa	6	20	the	the	DT
cord-015935-r2wd1yfa	6	21	identification	identification	NN
cord-015935-r2wd1yfa	6	22	of	of	IN
cord-015935-r2wd1yfa	6	23	common	common	JJ
cord-015935-r2wd1yfa	6	24	genetic	genetic	JJ
cord-015935-r2wd1yfa	6	25	variants	variant	NNS
cord-015935-r2wd1yfa	6	26	via	via	IN
cord-015935-r2wd1yfa	6	27	the	the	DT
cord-015935-r2wd1yfa	6	28	HapMap	HapMap	NNP
cord-015935-r2wd1yfa	6	29	project	project	NN
cord-015935-r2wd1yfa	6	30	(	(	-LRB-
cord-015935-r2wd1yfa	6	31	International	International	NNP
cord-015935-r2wd1yfa	6	32	HapMap	HapMap	NNP
cord-015935-r2wd1yfa	6	33	Consortium	Consortium	NNP
cord-015935-r2wd1yfa	6	34	,	,	,
cord-015935-r2wd1yfa	6	35	2005	2005	CD
cord-015935-r2wd1yfa	6	36	)	)	-RRB-
cord-015935-r2wd1yfa	6	37	,	,	,
cord-015935-r2wd1yfa	6	38	and	and	CC
cord-015935-r2wd1yfa	6	39	the	the	DT
cord-015935-r2wd1yfa	6	40	development	development	NN
cord-015935-r2wd1yfa	6	41	of	of	IN
cord-015935-r2wd1yfa	6	42	cost	cost	NN
cord-015935-r2wd1yfa	6	43	-	-	HYPH
cord-015935-r2wd1yfa	6	44	efficient	efficient	JJ
cord-015935-r2wd1yfa	6	45	genotyping	genotyping	NN
cord-015935-r2wd1yfa	6	46	and	and	CC
cord-015935-r2wd1yfa	6	47	analysis	analysis	NN
cord-015935-r2wd1yfa	6	48	technologies	technology	NNS
cord-015935-r2wd1yfa	6	49	(	(	-LRB-
cord-015935-r2wd1yfa	6	50	Losh	Losh	NNP
cord-015935-r2wd1yfa	6	51	,	,	,
cord-015935-r2wd1yfa	6	52	Sullivan	Sullivan	NNP
cord-015935-r2wd1yfa	6	53	,	,	,
cord-015935-r2wd1yfa	6	54	Trembath	Trembath	NNP
cord-015935-r2wd1yfa	6	55	,	,	,
cord-015935-r2wd1yfa	6	56	&	&	CC
cord-015935-r2wd1yfa	6	57	Piven	Piven	NNP
cord-015935-r2wd1yfa	6	58	,	,	,
cord-015935-r2wd1yfa	6	59	2008	2008	CD
cord-015935-r2wd1yfa	6	60	)	)	-RRB-
cord-015935-r2wd1yfa	6	61	.	.	.
cord-015935-r2wd1yfa	7	1	Improvement	improvement	NN
cord-015935-r2wd1yfa	7	2	in	in	IN
cord-015935-r2wd1yfa	7	3	technology	technology	NN
cord-015935-r2wd1yfa	7	4	has	have	VBZ
cord-015935-r2wd1yfa	7	5	led	lead	VBN
cord-015935-r2wd1yfa	7	6	to	to	IN
cord-015935-r2wd1yfa	7	7	improved	improve	VBN
cord-015935-r2wd1yfa	7	8	visualization	visualization	NN
cord-015935-r2wd1yfa	7	9	of	of	IN
cord-015935-r2wd1yfa	7	10	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	7	11	abnormality	abnormality	NN
cord-015935-r2wd1yfa	7	12	down	down	IN
cord-015935-r2wd1yfa	7	13	to	to	IN
cord-015935-r2wd1yfa	7	14	the	the	DT
cord-015935-r2wd1yfa	7	15	molecular	molecular	JJ
cord-015935-r2wd1yfa	7	16	level	level	NN
cord-015935-r2wd1yfa	7	17	.	.	.
cord-015935-r2wd1yfa	8	1	The	the	DT
cord-015935-r2wd1yfa	8	2	four	four	CD
cord-015935-r2wd1yfa	8	3	most	most	RBS
cord-015935-r2wd1yfa	8	4	common	common	JJ
cord-015935-r2wd1yfa	8	5	syndromes	syndrome	NNS
cord-015935-r2wd1yfa	8	6	associated	associate	VBN
cord-015935-r2wd1yfa	8	7	with	with	IN
cord-015935-r2wd1yfa	8	8	autism	autism	NN
cord-015935-r2wd1yfa	8	9	include	include	VBP
cord-015935-r2wd1yfa	8	10	fragile	fragile	JJ
cord-015935-r2wd1yfa	8	11	X	x	NN
cord-015935-r2wd1yfa	8	12	syndrome	syndrome	NN
cord-015935-r2wd1yfa	8	13	,	,	,
cord-015935-r2wd1yfa	8	14	tuberous	tuberous	JJ
cord-015935-r2wd1yfa	8	15	sclerosis	sclerosis	NN
cord-015935-r2wd1yfa	8	16	,	,	,
cord-015935-r2wd1yfa	8	17	15q	15q	NNS
cord-015935-r2wd1yfa	8	18	duplications	duplication	NNS
cord-015935-r2wd1yfa	8	19	,	,	,
cord-015935-r2wd1yfa	8	20	and	and	CC
cord-015935-r2wd1yfa	8	21	untreated	untreated	JJ
cord-015935-r2wd1yfa	8	22	phenylketonuria	phenylketonuria	NN
cord-015935-r2wd1yfa	8	23	(	(	-LRB-
cord-015935-r2wd1yfa	8	24	PKU	PKU	NNP
cord-015935-r2wd1yfa	8	25	;	;	:
cord-015935-r2wd1yfa	8	26	Costa	Costa	NNP
cord-015935-r2wd1yfa	8	27	e	e	NNP
cord-015935-r2wd1yfa	8	28	Silva	Silva	NNP
cord-015935-r2wd1yfa	8	29	,	,	,
cord-015935-r2wd1yfa	8	30	2008	2008	CD
cord-015935-r2wd1yfa	8	31	)	)	-RRB-
cord-015935-r2wd1yfa	8	32	.	.	.
cord-015935-r2wd1yfa	9	1	FXS	FXS	NNP
cord-015935-r2wd1yfa	9	2	and	and	CC
cord-015935-r2wd1yfa	9	3	15q	15q	NNS
cord-015935-r2wd1yfa	9	4	duplications	duplication	NNS
cord-015935-r2wd1yfa	9	5	are	be	VBP
cord-015935-r2wd1yfa	9	6	discussed	discuss	VBN
cord-015935-r2wd1yfa	9	7	within	within	IN
cord-015935-r2wd1yfa	9	8	the	the	DT
cord-015935-r2wd1yfa	9	9	context	context	NN
cord-015935-r2wd1yfa	9	10	of	of	IN
cord-015935-r2wd1yfa	9	11	cytogenetics	cytogenetic	NNS
cord-015935-r2wd1yfa	9	12	.	.	.
cord-015935-r2wd1yfa	10	1	TSC	TSC	NNP
cord-015935-r2wd1yfa	10	2	is	be	VBZ
cord-015935-r2wd1yfa	10	3	illustrated	illustrate	VBN
cord-015935-r2wd1yfa	10	4	within	within	IN
cord-015935-r2wd1yfa	10	5	the	the	DT
cord-015935-r2wd1yfa	10	6	description	description	NN
cord-015935-r2wd1yfa	10	7	of	of	IN
cord-015935-r2wd1yfa	10	8	linkage	linkage	NN
cord-015935-r2wd1yfa	10	9	analysis	analysis	NN
cord-015935-r2wd1yfa	10	10	.	.	.
cord-015935-r2wd1yfa	11	1	an	an	DT
cord-015935-r2wd1yfa	11	2	affected	affected	JJ
cord-015935-r2wd1yfa	11	3	sibling	sibling	NN
cord-015935-r2wd1yfa	11	4	-	-	HYPH
cord-015935-r2wd1yfa	11	5	pair	pair	NN
cord-015935-r2wd1yfa	11	6	design	design	NN
cord-015935-r2wd1yfa	11	7	in	in	IN
cord-015935-r2wd1yfa	11	8	multiplex	multiplex	NN
cord-015935-r2wd1yfa	11	9	(	(	-LRB-
cord-015935-r2wd1yfa	11	10	having	have	VBG
cord-015935-r2wd1yfa	11	11	more	more	JJR
cord-015935-r2wd1yfa	11	12	than	than	IN
cord-015935-r2wd1yfa	11	13	one	one	CD
cord-015935-r2wd1yfa	11	14	affected	affected	JJ
cord-015935-r2wd1yfa	11	15	member	member	NN
cord-015935-r2wd1yfa	11	16	)	)	-RRB-
cord-015935-r2wd1yfa	11	17	families	family	NNS
cord-015935-r2wd1yfa	11	18	.	.	.
cord-015935-r2wd1yfa	12	1	This	this	DT
cord-015935-r2wd1yfa	12	2	led	lead	VBD
cord-015935-r2wd1yfa	12	3	to	to	IN
cord-015935-r2wd1yfa	12	4	the	the	DT
cord-015935-r2wd1yfa	12	5	identification	identification	NN
cord-015935-r2wd1yfa	12	6	of	of	IN
cord-015935-r2wd1yfa	12	7	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	12	8	abnormalities	abnormality	NNS
cord-015935-r2wd1yfa	12	9	in	in	IN
cord-015935-r2wd1yfa	12	10	such	such	JJ
cord-015935-r2wd1yfa	12	11	conditions	condition	NNS
cord-015935-r2wd1yfa	12	12	as	as	IN
cord-015935-r2wd1yfa	12	13	neurofibromatosis	neurofibromatosis	NN
cord-015935-r2wd1yfa	12	14	,	,	,
cord-015935-r2wd1yfa	12	15	tuberous	tuberous	JJ
cord-015935-r2wd1yfa	12	16	sclerosis	sclerosis	NN
cord-015935-r2wd1yfa	12	17	,	,	,
cord-015935-r2wd1yfa	12	18	and	and	CC
cord-015935-r2wd1yfa	12	19	dyslexia	dyslexia	NNP
cord-015935-r2wd1yfa	12	20	(	(	-LRB-
cord-015935-r2wd1yfa	12	21	Smith	Smith	NNP
cord-015935-r2wd1yfa	12	22	,	,	,
cord-015935-r2wd1yfa	12	23	2007	2007	CD
cord-015935-r2wd1yfa	12	24	)	)	-RRB-
cord-015935-r2wd1yfa	12	25	.	.	.
cord-015935-r2wd1yfa	13	1	Improving	improve	VBG
cord-015935-r2wd1yfa	13	2	technology	technology	NN
cord-015935-r2wd1yfa	13	3	in	in	IN
cord-015935-r2wd1yfa	13	4	the	the	DT
cord-015935-r2wd1yfa	13	5	1990s	1990	NNS
cord-015935-r2wd1yfa	13	6	enabled	enable	VBD
cord-015935-r2wd1yfa	13	7	the	the	DT
cord-015935-r2wd1yfa	13	8	detection	detection	NN
cord-015935-r2wd1yfa	13	9	of	of	IN
cord-015935-r2wd1yfa	13	10	small	small	JJ
cord-015935-r2wd1yfa	13	11	genomic	genomic	JJ
cord-015935-r2wd1yfa	13	12	alterations	alteration	NNS
cord-015935-r2wd1yfa	13	13	of	of	IN
cord-015935-r2wd1yfa	13	14	50	50	CD
cord-015935-r2wd1yfa	13	15	-	-	SYM
cord-015935-r2wd1yfa	13	16	100	100	CD
cord-015935-r2wd1yfa	13	17	kb	kb	NNS
cord-015935-r2wd1yfa	13	18	and	and	CC
cord-015935-r2wd1yfa	13	19	the	the	DT
cord-015935-r2wd1yfa	13	20	direct	direct	JJ
cord-015935-r2wd1yfa	13	21	visualization	visualization	NN
cord-015935-r2wd1yfa	13	22	of	of	IN
cord-015935-r2wd1yfa	13	23	these	these	DT
cord-015935-r2wd1yfa	13	24	alterations	alteration	NNS
cord-015935-r2wd1yfa	13	25	in	in	IN
cord-015935-r2wd1yfa	13	26	uncultured	uncultured	JJ
cord-015935-r2wd1yfa	13	27	cells	cell	NNS
cord-015935-r2wd1yfa	13	28	via	via	IN
cord-015935-r2wd1yfa	13	29	fluorescent	fluorescent	NN
cord-015935-r2wd1yfa	13	30	in	in	IN
cord-015935-r2wd1yfa	13	31	situ	situ	JJ
cord-015935-r2wd1yfa	13	32	hybridization	hybridization	NN
cord-015935-r2wd1yfa	13	33	(	(	-LRB-
cord-015935-r2wd1yfa	13	34	FISH	fish	NN
cord-015935-r2wd1yfa	13	35	)	)	-RRB-
cord-015935-r2wd1yfa	13	36	.	.	.
cord-015935-r2wd1yfa	14	1	This	this	DT
cord-015935-r2wd1yfa	14	2	technique	technique	NN
cord-015935-r2wd1yfa	14	3	ushered	usher	VBD
cord-015935-r2wd1yfa	14	4	in	in	IN
cord-015935-r2wd1yfa	14	5	the	the	DT
cord-015935-r2wd1yfa	14	6	field	field	NN
cord-015935-r2wd1yfa	14	7	of	of	IN
cord-015935-r2wd1yfa	14	8	molecular	molecular	JJ
cord-015935-r2wd1yfa	14	9	genetics	genetic	NNS
cord-015935-r2wd1yfa	14	10	(	(	-LRB-
cord-015935-r2wd1yfa	14	11	Li	Li	NNP
cord-015935-r2wd1yfa	14	12	&	&	CC
cord-015935-r2wd1yfa	14	13	Andersson	Andersson	NNP
cord-015935-r2wd1yfa	14	14	,	,	,
cord-015935-r2wd1yfa	14	15	2009	2009	CD
cord-015935-r2wd1yfa	14	16	)	)	-RRB-
cord-015935-r2wd1yfa	14	17	and	and	CC
cord-015935-r2wd1yfa	14	18	allowed	allow	VBD
cord-015935-r2wd1yfa	14	19	the	the	DT
cord-015935-r2wd1yfa	14	20	identification	identification	NN
cord-015935-r2wd1yfa	14	21	of	of	IN
cord-015935-r2wd1yfa	14	22	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	14	23	microdeletions	microdeletion	NNS
cord-015935-r2wd1yfa	14	24	and	and	CC
cord-015935-r2wd1yfa	14	25	duplications	duplication	NNS
cord-015935-r2wd1yfa	14	26	in	in	IN
cord-015935-r2wd1yfa	14	27	areas	area	NNS
cord-015935-r2wd1yfa	14	28	of	of	IN
cord-015935-r2wd1yfa	14	29	the	the	DT
cord-015935-r2wd1yfa	14	30	chromosome	chromosome	NN
cord-015935-r2wd1yfa	14	31	where	where	WRB
cord-015935-r2wd1yfa	14	32	there	there	EX
cord-015935-r2wd1yfa	14	33	is	be	VBZ
cord-015935-r2wd1yfa	14	34	already	already	RB
cord-015935-r2wd1yfa	14	35	high	high	JJ
cord-015935-r2wd1yfa	14	36	suspicion	suspicion	NN
cord-015935-r2wd1yfa	14	37	that	that	IN
cord-015935-r2wd1yfa	14	38	abnormality	abnormality	NN
cord-015935-r2wd1yfa	14	39	would	would	MD
cord-015935-r2wd1yfa	14	40	exist	exist	VB
cord-015935-r2wd1yfa	14	41	.	.	.
cord-015935-r2wd1yfa	15	1	FISH	fish	NN
cord-015935-r2wd1yfa	15	2	enables	enable	VBZ
cord-015935-r2wd1yfa	15	3	prenatal	prenatal	JJ
cord-015935-r2wd1yfa	15	4	and	and	CC
cord-015935-r2wd1yfa	15	5	cancer	cancer	NN
cord-015935-r2wd1yfa	15	6	genetics	genetic	NNS
cord-015935-r2wd1yfa	15	7	screening	screening	NN
cord-015935-r2wd1yfa	15	8	and	and	CC
cord-015935-r2wd1yfa	15	9	has	have	VBZ
cord-015935-r2wd1yfa	15	10	led	lead	VBN
cord-015935-r2wd1yfa	15	11	to	to	IN
cord-015935-r2wd1yfa	15	12	the	the	DT
cord-015935-r2wd1yfa	15	13	identification	identification	NN
cord-015935-r2wd1yfa	15	14	of	of	IN
cord-015935-r2wd1yfa	15	15	genetic	genetic	JJ
cord-015935-r2wd1yfa	15	16	aberrations	aberration	NNS
cord-015935-r2wd1yfa	15	17	associated	associate	VBN
cord-015935-r2wd1yfa	15	18	with	with	IN
cord-015935-r2wd1yfa	15	19	Angelman	Angelman	NNP
cord-015935-r2wd1yfa	15	20	's	's	POS
cord-015935-r2wd1yfa	15	21	and	and	CC
cord-015935-r2wd1yfa	15	22	Prader	Prader	NNP
cord-015935-r2wd1yfa	15	23	Willi	Willi	NNP
cord-015935-r2wd1yfa	15	24	syndromes	syndrome	NNS
cord-015935-r2wd1yfa	15	25	.	.	.
cord-015935-r2wd1yfa	16	1	In	in	IN
cord-015935-r2wd1yfa	16	2	the	the	DT
cord-015935-r2wd1yfa	16	3	past	past	JJ
cord-015935-r2wd1yfa	16	4	decade	decade	NN
cord-015935-r2wd1yfa	16	5	,	,	,
cord-015935-r2wd1yfa	16	6	microarray	microarray	NN
cord-015935-r2wd1yfa	16	7	cytogenetics	cytogenetic	NNS
cord-015935-r2wd1yfa	16	8	has	have	VBZ
cord-015935-r2wd1yfa	16	9	permitted	permit	VBN
cord-015935-r2wd1yfa	16	10	the	the	DT
cord-015935-r2wd1yfa	16	11	study	study	NN
cord-015935-r2wd1yfa	16	12	of	of	IN
cord-015935-r2wd1yfa	16	13	the	the	DT
cord-015935-r2wd1yfa	16	14	entire	entire	JJ
cord-015935-r2wd1yfa	16	15	genome	genome	NN
cord-015935-r2wd1yfa	16	16	on	on	IN
cord-015935-r2wd1yfa	16	17	a	a	DT
cord-015935-r2wd1yfa	16	18	single	single	JJ
cord-015935-r2wd1yfa	16	19	chip	chip	NN
cord-015935-r2wd1yfa	16	20	with	with	IN
cord-015935-r2wd1yfa	16	21	resolution	resolution	NN
cord-015935-r2wd1yfa	16	22	as	as	RB
cord-015935-r2wd1yfa	16	23	fine	fine	JJ
cord-015935-r2wd1yfa	16	24	as	as	IN
cord-015935-r2wd1yfa	16	25	a	a	DT
cord-015935-r2wd1yfa	16	26	few	few	JJ
cord-015935-r2wd1yfa	16	27	hundred	hundred	CD
cord-015935-r2wd1yfa	16	28	base	base	NN
cord-015935-r2wd1yfa	16	29	pairs	pair	NNS
cord-015935-r2wd1yfa	16	30	(	(	-LRB-
cord-015935-r2wd1yfa	16	31	Li	Li	NNP
cord-015935-r2wd1yfa	16	32	&	&	CC
cord-015935-r2wd1yfa	16	33	Andersson	Andersson	NNP
cord-015935-r2wd1yfa	16	34	,	,	,
cord-015935-r2wd1yfa	16	35	2009	2009	CD
cord-015935-r2wd1yfa	16	36	)	)	-RRB-
cord-015935-r2wd1yfa	16	37	.	.	.
cord-015935-r2wd1yfa	17	1	Such	such	JJ
cord-015935-r2wd1yfa	17	2	microarray	microarray	NN
cord-015935-r2wd1yfa	17	3	technology	technology	NN
cord-015935-r2wd1yfa	17	4	represents	represent	VBZ
cord-015935-r2wd1yfa	17	5	a	a	DT
cord-015935-r2wd1yfa	17	6	union	union	NN
cord-015935-r2wd1yfa	17	7	between	between	IN
cord-015935-r2wd1yfa	17	8	molecular	molecular	JJ
cord-015935-r2wd1yfa	17	9	genetics	genetic	NNS
cord-015935-r2wd1yfa	17	10	and	and	CC
cord-015935-r2wd1yfa	17	11	classical	classical	JJ
cord-015935-r2wd1yfa	17	12	cytogenetics	cytogenetic	NNS
cord-015935-r2wd1yfa	17	13	.	.	.
cord-015935-r2wd1yfa	18	1	Two	two	CD
cord-015935-r2wd1yfa	18	2	types	type	NNS
cord-015935-r2wd1yfa	18	3	of	of	IN
cord-015935-r2wd1yfa	18	4	microarray	microarray	NN
cord-015935-r2wd1yfa	18	5	technology	technology	NN
cord-015935-r2wd1yfa	18	6	are	be	VBP
cord-015935-r2wd1yfa	18	7	used	use	VBN
cord-015935-r2wd1yfa	18	8	clinically	clinically	RB
cord-015935-r2wd1yfa	18	9	:	:	:
cord-015935-r2wd1yfa	18	10	comparative	comparative	JJ
cord-015935-r2wd1yfa	18	11	genomic	genomic	JJ
cord-015935-r2wd1yfa	18	12	hybridization	hybridization	NN
cord-015935-r2wd1yfa	18	13	(	(	-LRB-
cord-015935-r2wd1yfa	18	14	CGH	CGH	NNP
cord-015935-r2wd1yfa	18	15	)	)	-RRB-
cord-015935-r2wd1yfa	18	16	and	and	CC
cord-015935-r2wd1yfa	18	17	single	single	JJ
cord-015935-r2wd1yfa	18	18	-	-	HYPH
cord-015935-r2wd1yfa	18	19	nucleotide	nucleotide	JJ
cord-015935-r2wd1yfa	18	20	polymorphism	polymorphism	NN
cord-015935-r2wd1yfa	18	21	(	(	-LRB-
cord-015935-r2wd1yfa	18	22	SNP	SNP	NNP
cord-015935-r2wd1yfa	18	23	)	)	-RRB-
cord-015935-r2wd1yfa	18	24	analysis	analysis	NN
cord-015935-r2wd1yfa	18	25	.	.	.
cord-015935-r2wd1yfa	19	1	CGH	CGH	NNP
cord-015935-r2wd1yfa	19	2	directly	directly	RB
cord-015935-r2wd1yfa	19	3	measures	measure	VBZ
cord-015935-r2wd1yfa	19	4	copy	copy	VBP
cord-015935-r2wd1yfa	19	5	number	number	NN
cord-015935-r2wd1yfa	19	6	differences	difference	NNS
cord-015935-r2wd1yfa	19	7	between	between	IN
cord-015935-r2wd1yfa	19	8	a	a	DT
cord-015935-r2wd1yfa	19	9	patient	patient	NN
cord-015935-r2wd1yfa	19	10	's	's	POS
cord-015935-r2wd1yfa	19	11	DNA	dna	NN
cord-015935-r2wd1yfa	19	12	and	and	CC
cord-015935-r2wd1yfa	19	13	a	a	DT
cord-015935-r2wd1yfa	19	14	normal	normal	JJ
cord-015935-r2wd1yfa	19	15	reference	reference	NN
cord-015935-r2wd1yfa	19	16	DNA	dna	NN
cord-015935-r2wd1yfa	19	17	spanning	span	VBG
cord-015935-r2wd1yfa	19	18	known	know	VBN
cord-015935-r2wd1yfa	19	19	genes	gene	NNS
cord-015935-r2wd1yfa	19	20	,	,	,
cord-015935-r2wd1yfa	19	21	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	19	22	regions	region	NNS
cord-015935-r2wd1yfa	19	23	,	,	,
cord-015935-r2wd1yfa	19	24	or	or	CC
cord-015935-r2wd1yfa	19	25	across	across	IN
cord-015935-r2wd1yfa	19	26	the	the	DT
cord-015935-r2wd1yfa	19	27	entire	entire	JJ
cord-015935-r2wd1yfa	19	28	genome	genome	NN
cord-015935-r2wd1yfa	19	29	.	.	.
cord-015935-r2wd1yfa	20	1	SNP	SNP	NNP
cord-015935-r2wd1yfa	20	2	analysis	analysis	NN
cord-015935-r2wd1yfa	20	3	,	,	,
cord-015935-r2wd1yfa	20	4	on	on	IN
cord-015935-r2wd1yfa	20	5	the	the	DT
cord-015935-r2wd1yfa	20	6	other	other	JJ
cord-015935-r2wd1yfa	20	7	hand	hand	NN
cord-015935-r2wd1yfa	20	8	,	,	,
cord-015935-r2wd1yfa	20	9	provides	provide	VBZ
cord-015935-r2wd1yfa	20	10	identification	identification	NN
cord-015935-r2wd1yfa	20	11	of	of	IN
cord-015935-r2wd1yfa	20	12	a	a	DT
cord-015935-r2wd1yfa	20	13	single	single	JJ
cord-015935-r2wd1yfa	20	14	point	point	NN
cord-015935-r2wd1yfa	20	15	mutation	mutation	NN
cord-015935-r2wd1yfa	20	16	via	via	IN
cord-015935-r2wd1yfa	20	17	sequencing	sequence	VBG
cord-015935-r2wd1yfa	20	18	the	the	DT
cord-015935-r2wd1yfa	20	19	gene	gene	NN
cord-015935-r2wd1yfa	20	20	in	in	IN
cord-015935-r2wd1yfa	20	21	areas	area	NNS
cord-015935-r2wd1yfa	20	22	of	of	IN
cord-015935-r2wd1yfa	20	23	suspected	suspect	VBN
cord-015935-r2wd1yfa	20	24	abnormality	abnormality	NN
cord-015935-r2wd1yfa	20	25	,	,	,
cord-015935-r2wd1yfa	20	26	previously	previously	RB
cord-015935-r2wd1yfa	20	27	identified	identify	VBN
cord-015935-r2wd1yfa	20	28	via	via	IN
cord-015935-r2wd1yfa	20	29	CGH	CGH	NNP
cord-015935-r2wd1yfa	20	30	or	or	CC
cord-015935-r2wd1yfa	20	31	FISH	fish	NN
cord-015935-r2wd1yfa	20	32	.	.	.
cord-015935-r2wd1yfa	21	1	Another	another	DT
cord-015935-r2wd1yfa	21	2	offshoot	offshoot	NN
cord-015935-r2wd1yfa	21	3	of	of	IN
cord-015935-r2wd1yfa	21	4	microarray	microarray	NN
cord-015935-r2wd1yfa	21	5	technology	technology	NN
cord-015935-r2wd1yfa	21	6	is	be	VBZ
cord-015935-r2wd1yfa	21	7	submicroscopic	submicroscopic	JJ
cord-015935-r2wd1yfa	21	8	chromosome	chromosome	NN
cord-015935-r2wd1yfa	21	9	copy	copy	NN
cord-015935-r2wd1yfa	21	10	number	number	NN
cord-015935-r2wd1yfa	21	11	variation	variation	NN
cord-015935-r2wd1yfa	21	12	(	(	-LRB-
cord-015935-r2wd1yfa	21	13	CNV	CNV	NNP
cord-015935-r2wd1yfa	21	14	)	)	-RRB-
cord-015935-r2wd1yfa	21	15	analysis	analysis	NN
cord-015935-r2wd1yfa	21	16	,	,	,
cord-015935-r2wd1yfa	21	17	in	in	IN
cord-015935-r2wd1yfa	21	18	which	which	WDT
cord-015935-r2wd1yfa	21	19	deletions	deletion	NNS
cord-015935-r2wd1yfa	21	20	or	or	CC
cord-015935-r2wd1yfa	21	21	duplications	duplication	NNS
cord-015935-r2wd1yfa	21	22	involving	involve	VBG
cord-015935-r2wd1yfa	21	23	>	>	XX
cord-015935-r2wd1yfa	21	24	1-kb	1-kb	CD
cord-015935-r2wd1yfa	21	25	DNA	dna	NN
cord-015935-r2wd1yfa	21	26	have	have	VBP
cord-015935-r2wd1yfa	21	27	been	be	VBN
cord-015935-r2wd1yfa	21	28	detected	detect	VBN
cord-015935-r2wd1yfa	21	29	in	in	IN
cord-015935-r2wd1yfa	21	30	patients	patient	NNS
cord-015935-r2wd1yfa	21	31	with	with	IN
cord-015935-r2wd1yfa	21	32	mental	mental	JJ
cord-015935-r2wd1yfa	21	33	retardation	retardation	NN
cord-015935-r2wd1yfa	21	34	,	,	,
cord-015935-r2wd1yfa	21	35	autism	autism	NN
cord-015935-r2wd1yfa	21	36	,	,	,
cord-015935-r2wd1yfa	21	37	and	and	CC
cord-015935-r2wd1yfa	21	38	multiple	multiple	JJ
cord-015935-r2wd1yfa	21	39	congenital	congenital	JJ
cord-015935-r2wd1yfa	21	40	anomalies	anomaly	NNS
cord-015935-r2wd1yfa	21	41	.	.	.
cord-015935-r2wd1yfa	22	1	There	there	EX
cord-015935-r2wd1yfa	22	2	are	be	VBP
cord-015935-r2wd1yfa	22	3	several	several	JJ
cord-015935-r2wd1yfa	22	4	recent	recent	JJ
cord-015935-r2wd1yfa	22	5	,	,	,
cord-015935-r2wd1yfa	22	6	detailed	detailed	JJ
cord-015935-r2wd1yfa	22	7	reviews	review	NNS
cord-015935-r2wd1yfa	22	8	of	of	IN
cord-015935-r2wd1yfa	22	9	the	the	DT
cord-015935-r2wd1yfa	22	10	genetics	genetic	NNS
cord-015935-r2wd1yfa	22	11	of	of	IN
cord-015935-r2wd1yfa	22	12	autism	autism	NN
cord-015935-r2wd1yfa	22	13	(	(	-LRB-
cord-015935-r2wd1yfa	22	14	Abrahams	Abrahams	NNP
cord-015935-r2wd1yfa	22	15	&	&	CC
cord-015935-r2wd1yfa	22	16	Geschwind	Geschwind	NNP
cord-015935-r2wd1yfa	22	17	,	,	,
cord-015935-r2wd1yfa	22	18	2008	2008	CD
cord-015935-r2wd1yfa	22	19	;	;	:
cord-015935-r2wd1yfa	22	20	Li	Li	NNP
cord-015935-r2wd1yfa	22	21	&	&	CC
cord-015935-r2wd1yfa	22	22	Andersson	Andersson	NNP
cord-015935-r2wd1yfa	22	23	,	,	,
cord-015935-r2wd1yfa	22	24	2009	2009	CD
cord-015935-r2wd1yfa	22	25	;	;	:
cord-015935-r2wd1yfa	22	26	Losh	Losh	NNP
cord-015935-r2wd1yfa	22	27	et	et	NNP
cord-015935-r2wd1yfa	22	28	al	al	NNP
cord-015935-r2wd1yfa	22	29	.	.	NNP
cord-015935-r2wd1yfa	22	30	,	,	,
cord-015935-r2wd1yfa	22	31	2008	2008	CD
cord-015935-r2wd1yfa	22	32	;	;	:
cord-015935-r2wd1yfa	22	33	O'Roak	O'Roak	NNP
cord-015935-r2wd1yfa	22	34	&	&	CC
cord-015935-r2wd1yfa	22	35	State	State	NNP
cord-015935-r2wd1yfa	22	36	,	,	,
cord-015935-r2wd1yfa	22	37	2008	2008	CD
cord-015935-r2wd1yfa	22	38	)	)	-RRB-
cord-015935-r2wd1yfa	22	39	and	and	CC
cord-015935-r2wd1yfa	22	40	this	this	DT
cord-015935-r2wd1yfa	22	41	chapter	chapter	NN
cord-015935-r2wd1yfa	22	42	summarizes	summarize	VBZ
cord-015935-r2wd1yfa	22	43	those	those	DT
cord-015935-r2wd1yfa	22	44	reviews	review	NNS
cord-015935-r2wd1yfa	22	45	.	.	.
cord-015935-r2wd1yfa	23	1	The	the	DT
cord-015935-r2wd1yfa	23	2	reader	reader	NN
cord-015935-r2wd1yfa	23	3	is	be	VBZ
cord-015935-r2wd1yfa	23	4	encouraged	encourage	VBN
cord-015935-r2wd1yfa	23	5	to	to	TO
cord-015935-r2wd1yfa	23	6	first	first	JJ
cord-015935-r2wd1yfa	23	7	review	review	VB
cord-015935-r2wd1yfa	23	8	the	the	DT
cord-015935-r2wd1yfa	23	9	overview	overview	NN
cord-015935-r2wd1yfa	23	10	of	of	IN
cord-015935-r2wd1yfa	23	11	gene	gene	NN
cord-015935-r2wd1yfa	23	12	expression	expression	NN
cord-015935-r2wd1yfa	23	13	(	(	-LRB-
cord-015935-r2wd1yfa	23	14	Box	Box	NNP
cord-015935-r2wd1yfa	23	15	6.1	6.1	CD
cord-015935-r2wd1yfa	23	16	)	)	-RRB-
cord-015935-r2wd1yfa	23	17	and	and	CC
cord-015935-r2wd1yfa	23	18	essential	essential	JJ
cord-015935-r2wd1yfa	23	19	nomenclature	nomenclature	NN
cord-015935-r2wd1yfa	23	20	used	use	VBN
cord-015935-r2wd1yfa	23	21	in	in	IN
cord-015935-r2wd1yfa	23	22	genetics	genetic	NNS
cord-015935-r2wd1yfa	23	23	(	(	-LRB-
cord-015935-r2wd1yfa	23	24	Box	Box	NNP
cord-015935-r2wd1yfa	23	25	6.2	6.2	CD
cord-015935-r2wd1yfa	23	26	)	)	-RRB-
cord-015935-r2wd1yfa	23	27	.	.	.
cord-015935-r2wd1yfa	24	1	In	in	IN
cord-015935-r2wd1yfa	24	2	addition	addition	NN
cord-015935-r2wd1yfa	24	3	,	,	,
cord-015935-r2wd1yfa	24	4	one	one	PRP
cord-015935-r2wd1yfa	24	5	must	must	MD
cord-015935-r2wd1yfa	24	6	understand	understand	VB
cord-015935-r2wd1yfa	24	7	basic	basic	JJ
cord-015935-r2wd1yfa	24	8	concepts	concept	NNS
cord-015935-r2wd1yfa	24	9	pertinent	pertinent	JJ
cord-015935-r2wd1yfa	24	10	to	to	IN
cord-015935-r2wd1yfa	24	11	brain	brain	NN
cord-015935-r2wd1yfa	24	12	development	development	NN
cord-015935-r2wd1yfa	24	13	(	(	-LRB-
cord-015935-r2wd1yfa	24	14	Box	Box	NNP
cord-015935-r2wd1yfa	24	15	6.3	6.3	CD
cord-015935-r2wd1yfa	24	16	)	)	-RRB-
cord-015935-r2wd1yfa	24	17	and	and	CC
cord-015935-r2wd1yfa	24	18	to	to	IN
cord-015935-r2wd1yfa	24	19	the	the	DT
cord-015935-r2wd1yfa	24	20	neurobiology	neurobiology	NN
cord-015935-r2wd1yfa	24	21	of	of	IN
cord-015935-r2wd1yfa	24	22	autism	autism	NN
cord-015935-r2wd1yfa	24	23	(	(	-LRB-
cord-015935-r2wd1yfa	24	24	Box	Box	NNP
cord-015935-r2wd1yfa	24	25	6.4	6.4	CD
cord-015935-r2wd1yfa	24	26	)	)	-RRB-
cord-015935-r2wd1yfa	24	27	in	in	IN
cord-015935-r2wd1yfa	24	28	order	order	NN
cord-015935-r2wd1yfa	24	29	to	to	TO
cord-015935-r2wd1yfa	24	30	understand	understand	VB
cord-015935-r2wd1yfa	24	31	its	-PRON-	PRP$
cord-015935-r2wd1yfa	24	32	genetics	genetic	NNS
cord-015935-r2wd1yfa	24	33	.	.	.
cord-015935-r2wd1yfa	25	1	For	for	IN
cord-015935-r2wd1yfa	25	2	example	example	NN
cord-015935-r2wd1yfa	25	3	,	,	,
cord-015935-r2wd1yfa	25	4	there	there	EX
cord-015935-r2wd1yfa	25	5	is	be	VBZ
cord-015935-r2wd1yfa	25	6	a	a	DT
cord-015935-r2wd1yfa	25	7	compelling	compelling	JJ
cord-015935-r2wd1yfa	25	8	rationale	rationale	NN
cord-015935-r2wd1yfa	25	9	that	that	WDT
cord-015935-r2wd1yfa	25	10	genetically	genetically	RB
cord-015935-r2wd1yfa	25	11	directed	direct	VBN
cord-015935-r2wd1yfa	25	12	mechanisms	mechanism	NNS
cord-015935-r2wd1yfa	25	13	that	that	WDT
cord-015935-r2wd1yfa	25	14	regulate	regulate	VBP
cord-015935-r2wd1yfa	25	15	the	the	DT
cord-015935-r2wd1yfa	25	16	assembly	assembly	NN
cord-015935-r2wd1yfa	25	17	of	of	IN
cord-015935-r2wd1yfa	25	18	the	the	DT
cord-015935-r2wd1yfa	25	19	brain	brain	NN
cord-015935-r2wd1yfa	25	20	during	during	IN
cord-015935-r2wd1yfa	25	21	embryogenesis	embryogenesis	NN
cord-015935-r2wd1yfa	25	22	,	,	,
cord-015935-r2wd1yfa	25	23	when	when	WRB
cord-015935-r2wd1yfa	25	24	gone	go	VBN
cord-015935-r2wd1yfa	25	25	awry	awry	JJ
cord-015935-r2wd1yfa	25	26	,	,	,
cord-015935-r2wd1yfa	25	27	may	may	MD
cord-015935-r2wd1yfa	25	28	cause	cause	VB
cord-015935-r2wd1yfa	25	29	autism	autism	NN
cord-015935-r2wd1yfa	25	30	(	(	-LRB-
cord-015935-r2wd1yfa	25	31	Costa	Costa	NNP
cord-015935-r2wd1yfa	25	32	e	e	NNP
cord-015935-r2wd1yfa	25	33	Silva	Silva	NNP
cord-015935-r2wd1yfa	25	34	,	,	,
cord-015935-r2wd1yfa	25	35	2008	2008	CD
cord-015935-r2wd1yfa	25	36	)	)	-RRB-
cord-015935-r2wd1yfa	25	37	.	.	.
cord-015935-r2wd1yfa	26	1	Box	Box	NNP
cord-015935-r2wd1yfa	26	2	6.1	6.1	CD
cord-015935-r2wd1yfa	26	3	Overview	Overview	NNP
cord-015935-r2wd1yfa	26	4	of	of	IN
cord-015935-r2wd1yfa	26	5	DNA	DNA	NNP
cord-015935-r2wd1yfa	26	6	Replication	Replication	NNP
cord-015935-r2wd1yfa	26	7	and	and	CC
cord-015935-r2wd1yfa	26	8	Gene	Gene	NNP
cord-015935-r2wd1yfa	26	9	Expression	Expression	NNP
cord-015935-r2wd1yfa	26	10	*	*	NFP
cord-015935-r2wd1yfa	26	11	Genes	gene	NNS
cord-015935-r2wd1yfa	26	12	.	.	.
cord-015935-r2wd1yfa	27	1	A	a	DT
cord-015935-r2wd1yfa	27	2	gene	gene	NN
cord-015935-r2wd1yfa	27	3	is	be	VBZ
cord-015935-r2wd1yfa	27	4	a	a	DT
cord-015935-r2wd1yfa	27	5	unit	unit	NN
cord-015935-r2wd1yfa	27	6	of	of	IN
cord-015935-r2wd1yfa	27	7	hereditary	hereditary	JJ
cord-015935-r2wd1yfa	27	8	material	material	NN
cord-015935-r2wd1yfa	27	9	located	locate	VBN
cord-015935-r2wd1yfa	27	10	in	in	IN
cord-015935-r2wd1yfa	27	11	a	a	DT
cord-015935-r2wd1yfa	27	12	specific	specific	JJ
cord-015935-r2wd1yfa	27	13	place	place	NN
cord-015935-r2wd1yfa	27	14	(	(	-LRB-
cord-015935-r2wd1yfa	27	15	locus	locus	NN
cord-015935-r2wd1yfa	27	16	)	)	-RRB-
cord-015935-r2wd1yfa	27	17	on	on	IN
cord-015935-r2wd1yfa	27	18	a	a	DT
cord-015935-r2wd1yfa	27	19	chromosome	chromosome	NN
cord-015935-r2wd1yfa	27	20	.	.	.
cord-015935-r2wd1yfa	28	1	Most	Most	JJS
cord-015935-r2wd1yfa	28	2	genes	gene	NNS
cord-015935-r2wd1yfa	28	3	carry	carry	VBP
cord-015935-r2wd1yfa	28	4	the	the	DT
cord-015935-r2wd1yfa	28	5	instructions	instruction	NNS
cord-015935-r2wd1yfa	28	6	for	for	IN
cord-015935-r2wd1yfa	28	7	producing	produce	VBG
cord-015935-r2wd1yfa	28	8	a	a	DT
cord-015935-r2wd1yfa	28	9	specific	specific	JJ
cord-015935-r2wd1yfa	28	10	protein	protein	NN
cord-015935-r2wd1yfa	28	11	.	.	.
cord-015935-r2wd1yfa	29	1	A	a	DT
cord-015935-r2wd1yfa	29	2	protein	protein	NN
cord-015935-r2wd1yfa	29	3	-	-	HYPH
cord-015935-r2wd1yfa	29	4	coding	code	VBG
cord-015935-r2wd1yfa	29	5	human	human	JJ
cord-015935-r2wd1yfa	29	6	gene	gene	NN
cord-015935-r2wd1yfa	29	7	will	will	MD
cord-015935-r2wd1yfa	29	8	have	have	VB
cord-015935-r2wd1yfa	29	9	a	a	DT
cord-015935-r2wd1yfa	29	10	coding	code	VBG
cord-015935-r2wd1yfa	29	11	sequence	sequence	NN
cord-015935-r2wd1yfa	29	12	,	,	,
cord-015935-r2wd1yfa	29	13	which	which	WDT
cord-015935-r2wd1yfa	29	14	contains	contain	VBZ
cord-015935-r2wd1yfa	29	15	the	the	DT
cord-015935-r2wd1yfa	29	16	information	information	NN
cord-015935-r2wd1yfa	29	17	for	for	IN
cord-015935-r2wd1yfa	29	18	protein	protein	NN
cord-015935-r2wd1yfa	29	19	production	production	NN
cord-015935-r2wd1yfa	29	20	.	.	.
cord-015935-r2wd1yfa	30	1	The	the	DT
cord-015935-r2wd1yfa	30	2	coding	code	VBG
cord-015935-r2wd1yfa	30	3	sequence	sequence	NN
cord-015935-r2wd1yfa	30	4	may	may	MD
cord-015935-r2wd1yfa	30	5	be	be	VB
cord-015935-r2wd1yfa	30	6	broken	break	VBN
cord-015935-r2wd1yfa	30	7	up	up	RP
cord-015935-r2wd1yfa	30	8	into	into	IN
cord-015935-r2wd1yfa	30	9	several	several	JJ
cord-015935-r2wd1yfa	30	10	sub	sub	NN
cord-015935-r2wd1yfa	30	11	-	-	NNS
cord-015935-r2wd1yfa	30	12	sequences	sequence	NNS
cord-015935-r2wd1yfa	30	13	,	,	,
cord-015935-r2wd1yfa	30	14	or	or	CC
cord-015935-r2wd1yfa	30	15	exons	exon	NNS
cord-015935-r2wd1yfa	30	16	,	,	,
cord-015935-r2wd1yfa	30	17	which	which	WDT
cord-015935-r2wd1yfa	30	18	are	be	VBP
cord-015935-r2wd1yfa	30	19	separated	separate	VBN
cord-015935-r2wd1yfa	30	20	by	by	IN
cord-015935-r2wd1yfa	30	21	noncoding	noncoding	JJ
cord-015935-r2wd1yfa	30	22	DNA	dna	NN
cord-015935-r2wd1yfa	30	23	sequences	sequence	NNS
cord-015935-r2wd1yfa	30	24	,	,	,
cord-015935-r2wd1yfa	30	25	or	or	CC
cord-015935-r2wd1yfa	30	26	introns	intron	NNS
cord-015935-r2wd1yfa	30	27	.	.	.
cord-015935-r2wd1yfa	31	1	The	the	DT
cord-015935-r2wd1yfa	31	2	coding	code	VBG
cord-015935-r2wd1yfa	31	3	sequence	sequence	NN
cord-015935-r2wd1yfa	31	4	is	be	VBZ
cord-015935-r2wd1yfa	31	5	flanked	flank	VBN
cord-015935-r2wd1yfa	31	6	by	by	IN
cord-015935-r2wd1yfa	31	7	a	a	DT
cord-015935-r2wd1yfa	31	8	promoter	promoter	NN
cord-015935-r2wd1yfa	31	9	and	and	CC
cord-015935-r2wd1yfa	31	10	(	(	-LRB-
cord-015935-r2wd1yfa	31	11	usually	usually	RB
cord-015935-r2wd1yfa	31	12	)	)	-RRB-
cord-015935-r2wd1yfa	31	13	a	a	DT
cord-015935-r2wd1yfa	31	14	5	5	CD
cord-015935-r2wd1yfa	31	15	-untranslated	-untranslated	JJ
cord-015935-r2wd1yfa	31	16	region	region	NN
cord-015935-r2wd1yfa	31	17	(	(	-LRB-
cord-015935-r2wd1yfa	31	18	5	5	CD
cord-015935-r2wd1yfa	31	19	-UTR	-utr	SYM
cord-015935-r2wd1yfa	31	20	)	)	-RRB-
cord-015935-r2wd1yfa	31	21	that	that	WDT
cord-015935-r2wd1yfa	31	22	occur	occur	VBP
cord-015935-r2wd1yfa	31	23	immediately	immediately	RB
cord-015935-r2wd1yfa	31	24	before	before	IN
cord-015935-r2wd1yfa	31	25	the	the	DT
cord-015935-r2wd1yfa	31	26	coding	code	VBG
cord-015935-r2wd1yfa	31	27	sequence	sequence	NN
cord-015935-r2wd1yfa	31	28	and	and	CC
cord-015935-r2wd1yfa	31	29	by	by	IN
cord-015935-r2wd1yfa	31	30	a	a	DT
cord-015935-r2wd1yfa	31	31	3	3	CD
cord-015935-r2wd1yfa	31	32	-UTR	-utr	NN
cord-015935-r2wd1yfa	31	33	and	and	CC
cord-015935-r2wd1yfa	31	34	a	a	DT
cord-015935-r2wd1yfa	31	35	terminator	terminator	NN
cord-015935-r2wd1yfa	31	36	that	that	WDT
cord-015935-r2wd1yfa	31	37	occur	occur	VBP
cord-015935-r2wd1yfa	31	38	immediately	immediately	RB
cord-015935-r2wd1yfa	31	39	after	after	IN
cord-015935-r2wd1yfa	31	40	the	the	DT
cord-015935-r2wd1yfa	31	41	coding	code	VBG
cord-015935-r2wd1yfa	31	42	sequence	sequence	NN
cord-015935-r2wd1yfa	31	43	.	.	.
cord-015935-r2wd1yfa	32	1	Promoters	promoter	NNS
cord-015935-r2wd1yfa	32	2	,	,	,
cord-015935-r2wd1yfa	32	3	terminators	terminator	NNS
cord-015935-r2wd1yfa	32	4	,	,	,
cord-015935-r2wd1yfa	32	5	UTRs	utr	NNS
cord-015935-r2wd1yfa	32	6	,	,	,
cord-015935-r2wd1yfa	32	7	and	and	CC
cord-015935-r2wd1yfa	32	8	introns	intron	NNS
cord-015935-r2wd1yfa	32	9	can	can	MD
cord-015935-r2wd1yfa	32	10	regulate	regulate	VB
cord-015935-r2wd1yfa	32	11	the	the	DT
cord-015935-r2wd1yfa	32	12	activity	activity	NN
cord-015935-r2wd1yfa	32	13	of	of	IN
cord-015935-r2wd1yfa	32	14	a	a	DT
cord-015935-r2wd1yfa	32	15	given	give	VBN
cord-015935-r2wd1yfa	32	16	gene	gene	NN
cord-015935-r2wd1yfa	32	17	.	.	.
cord-015935-r2wd1yfa	33	1	At	at	IN
cord-015935-r2wd1yfa	33	2	a	a	DT
cord-015935-r2wd1yfa	33	3	molecular	molecular	JJ
cord-015935-r2wd1yfa	33	4	level	level	NN
cord-015935-r2wd1yfa	33	5	,	,	,
cord-015935-r2wd1yfa	33	6	chromosomes	chromosome	NNS
cord-015935-r2wd1yfa	33	7	are	be	VBP
cord-015935-r2wd1yfa	33	8	composed	compose	VBN
cord-015935-r2wd1yfa	33	9	of	of	IN
cord-015935-r2wd1yfa	33	10	long	long	JJ
cord-015935-r2wd1yfa	33	11	chains	chain	NNS
cord-015935-r2wd1yfa	33	12	of	of	IN
cord-015935-r2wd1yfa	33	13	deoxyribonucleic	deoxyribonucleic	NN
cord-015935-r2wd1yfa	33	14	acid	acid	NN
cord-015935-r2wd1yfa	33	15	(	(	-LRB-
cord-015935-r2wd1yfa	33	16	DNA	DNA	NNP
cord-015935-r2wd1yfa	33	17	)	)	-RRB-
cord-015935-r2wd1yfa	33	18	upon	upon	IN
cord-015935-r2wd1yfa	33	19	which	which	WDT
cord-015935-r2wd1yfa	33	20	genes	gene	NNS
cord-015935-r2wd1yfa	33	21	are	be	VBP
cord-015935-r2wd1yfa	33	22	linearly	linearly	RB
cord-015935-r2wd1yfa	33	23	arranged	arrange	VBN
cord-015935-r2wd1yfa	33	24	.	.	.
cord-015935-r2wd1yfa	34	1	The	the	DT
cord-015935-r2wd1yfa	34	2	DNA	dna	NN
cord-015935-r2wd1yfa	34	3	exists	exist	VBZ
cord-015935-r2wd1yfa	34	4	in	in	IN
cord-015935-r2wd1yfa	34	5	a	a	DT
cord-015935-r2wd1yfa	34	6	double	double	JJ
cord-015935-r2wd1yfa	34	7	helix	helix	NN
cord-015935-r2wd1yfa	34	8	and	and	CC
cord-015935-r2wd1yfa	34	9	the	the	DT
cord-015935-r2wd1yfa	34	10	helical	helical	JJ
cord-015935-r2wd1yfa	34	11	strands	strand	NNS
cord-015935-r2wd1yfa	34	12	are	be	VBP
cord-015935-r2wd1yfa	34	13	usually	usually	RB
cord-015935-r2wd1yfa	34	14	wrapped	wrap	VBN
cord-015935-r2wd1yfa	34	15	around	around	IN
cord-015935-r2wd1yfa	34	16	histone	histone	NN
cord-015935-r2wd1yfa	34	17	proteins	protein	NNS
cord-015935-r2wd1yfa	34	18	.	.	.
cord-015935-r2wd1yfa	35	1	In	in	IN
cord-015935-r2wd1yfa	35	2	addition	addition	NN
cord-015935-r2wd1yfa	35	3	to	to	IN
cord-015935-r2wd1yfa	35	4	DNA	dna	NN
cord-015935-r2wd1yfa	35	5	and	and	CC
cord-015935-r2wd1yfa	35	6	histones	histone	NNS
cord-015935-r2wd1yfa	35	7	,	,	,
cord-015935-r2wd1yfa	35	8	chromosomes	chromosome	NNS
cord-015935-r2wd1yfa	35	9	contain	contain	VBP
cord-015935-r2wd1yfa	35	10	scaffolding	scaffold	VBG
cord-015935-r2wd1yfa	35	11	proteins	protein	NNS
cord-015935-r2wd1yfa	35	12	that	that	WDT
cord-015935-r2wd1yfa	35	13	provide	provide	VBP
cord-015935-r2wd1yfa	35	14	structural	structural	JJ
cord-015935-r2wd1yfa	35	15	support	support	NN
cord-015935-r2wd1yfa	35	16	and	and	CC
cord-015935-r2wd1yfa	35	17	may	may	MD
cord-015935-r2wd1yfa	35	18	also	also	RB
cord-015935-r2wd1yfa	35	19	participate	participate	VB
cord-015935-r2wd1yfa	35	20	in	in	IN
cord-015935-r2wd1yfa	35	21	gene	gene	NN
cord-015935-r2wd1yfa	35	22	regulation	regulation	NN
cord-015935-r2wd1yfa	35	23	.	.	.
cord-015935-r2wd1yfa	36	1	DNA	DNA	NNP
cord-015935-r2wd1yfa	36	2	is	be	VBZ
cord-015935-r2wd1yfa	36	3	a	a	DT
cord-015935-r2wd1yfa	36	4	molecule	molecule	NN
cord-015935-r2wd1yfa	36	5	composed	compose	VBN
cord-015935-r2wd1yfa	36	6	of	of	IN
cord-015935-r2wd1yfa	36	7	a	a	DT
cord-015935-r2wd1yfa	36	8	chain	chain	NN
cord-015935-r2wd1yfa	36	9	of	of	IN
cord-015935-r2wd1yfa	36	10	four	four	CD
cord-015935-r2wd1yfa	36	11	different	different	JJ
cord-015935-r2wd1yfa	36	12	types	type	NNS
cord-015935-r2wd1yfa	36	13	of	of	IN
cord-015935-r2wd1yfa	36	14	nucleotides	nucleotide	NNS
cord-015935-r2wd1yfa	36	15	.	.	.
cord-015935-r2wd1yfa	37	1	It	-PRON-	PRP
cord-015935-r2wd1yfa	37	2	is	be	VBZ
cord-015935-r2wd1yfa	37	3	the	the	DT
cord-015935-r2wd1yfa	37	4	sequence	sequence	NN
cord-015935-r2wd1yfa	37	5	of	of	IN
cord-015935-r2wd1yfa	37	6	these	these	DT
cord-015935-r2wd1yfa	37	7	nucleotides	nucleotide	NNS
cord-015935-r2wd1yfa	37	8	that	that	WDT
cord-015935-r2wd1yfa	37	9	is	be	VBZ
cord-015935-r2wd1yfa	37	10	the	the	DT
cord-015935-r2wd1yfa	37	11	genetic	genetic	JJ
cord-015935-r2wd1yfa	37	12	information	information	NN
cord-015935-r2wd1yfa	37	13	that	that	WDT
cord-015935-r2wd1yfa	37	14	organisms	organism	NNS
cord-015935-r2wd1yfa	37	15	inherit	inherit	VBP
cord-015935-r2wd1yfa	37	16	.	.	.
cord-015935-r2wd1yfa	38	1	DNA	DNA	NNP
cord-015935-r2wd1yfa	38	2	is	be	VBZ
cord-015935-r2wd1yfa	38	3	double	double	RB
cord-015935-r2wd1yfa	38	4	stranded	strand	VBN
cord-015935-r2wd1yfa	38	5	with	with	IN
cord-015935-r2wd1yfa	38	6	nucleotides	nucleotide	NNS
cord-015935-r2wd1yfa	38	7	on	on	IN
cord-015935-r2wd1yfa	38	8	each	each	DT
cord-015935-r2wd1yfa	38	9	strand	strand	NN
cord-015935-r2wd1yfa	38	10	complementary	complementary	JJ
cord-015935-r2wd1yfa	38	11	to	to	IN
cord-015935-r2wd1yfa	38	12	each	each	DT
cord-015935-r2wd1yfa	38	13	other	other	JJ
cord-015935-r2wd1yfa	38	14	.	.	.
cord-015935-r2wd1yfa	39	1	Each	each	DT
cord-015935-r2wd1yfa	39	2	strand	strand	NN
cord-015935-r2wd1yfa	39	3	acts	act	VBZ
cord-015935-r2wd1yfa	39	4	as	as	IN
cord-015935-r2wd1yfa	39	5	a	a	DT
cord-015935-r2wd1yfa	39	6	template	template	NN
cord-015935-r2wd1yfa	39	7	for	for	IN
cord-015935-r2wd1yfa	39	8	creating	create	VBG
cord-015935-r2wd1yfa	39	9	a	a	DT
cord-015935-r2wd1yfa	39	10	new	new	JJ
cord-015935-r2wd1yfa	39	11	partner	partner	NN
cord-015935-r2wd1yfa	39	12	strand	strand	NN
cord-015935-r2wd1yfa	39	13	.	.	.
cord-015935-r2wd1yfa	40	1	This	this	DT
cord-015935-r2wd1yfa	40	2	is	be	VBZ
cord-015935-r2wd1yfa	40	3	the	the	DT
cord-015935-r2wd1yfa	40	4	physical	physical	JJ
cord-015935-r2wd1yfa	40	5	method	method	NN
cord-015935-r2wd1yfa	40	6	for	for	IN
cord-015935-r2wd1yfa	40	7	making	make	VBG
cord-015935-r2wd1yfa	40	8	copies	copy	NNS
cord-015935-r2wd1yfa	40	9	of	of	IN
cord-015935-r2wd1yfa	40	10	genes	gene	NNS
cord-015935-r2wd1yfa	40	11	that	that	WDT
cord-015935-r2wd1yfa	40	12	are	be	VBP
cord-015935-r2wd1yfa	40	13	inherited	inherit	VBN
cord-015935-r2wd1yfa	40	14	.	.	.
cord-015935-r2wd1yfa	41	1	Both	both	DT
cord-015935-r2wd1yfa	41	2	individual	individual	JJ
cord-015935-r2wd1yfa	41	3	DNA	dna	NN
cord-015935-r2wd1yfa	41	4	nucleotides	nucleotide	NNS
cord-015935-r2wd1yfa	41	5	and	and	CC
cord-015935-r2wd1yfa	41	6	DNAassociated	dnaassociate	VBN
cord-015935-r2wd1yfa	41	7	proteins	protein	NNS
cord-015935-r2wd1yfa	41	8	can	can	MD
cord-015935-r2wd1yfa	41	9	be	be	VB
cord-015935-r2wd1yfa	41	10	chemically	chemically	RB
cord-015935-r2wd1yfa	41	11	modified	modify	VBN
cord-015935-r2wd1yfa	41	12	to	to	TO
cord-015935-r2wd1yfa	41	13	produce	produce	VB
cord-015935-r2wd1yfa	41	14	epigenetic	epigenetic	JJ
cord-015935-r2wd1yfa	41	15	variation	variation	NN
cord-015935-r2wd1yfa	41	16	that	that	WDT
cord-015935-r2wd1yfa	41	17	may	may	MD
cord-015935-r2wd1yfa	41	18	be	be	VB
cord-015935-r2wd1yfa	41	19	in	in	IN
cord-015935-r2wd1yfa	41	20	response	response	NN
cord-015935-r2wd1yfa	41	21	to	to	IN
cord-015935-r2wd1yfa	41	22	environmental	environmental	JJ
cord-015935-r2wd1yfa	41	23	conditions	condition	NNS
cord-015935-r2wd1yfa	41	24	and	and	CC
cord-015935-r2wd1yfa	41	25	might	may	MD
cord-015935-r2wd1yfa	41	26	or	or	CC
cord-015935-r2wd1yfa	41	27	might	may	MD
cord-015935-r2wd1yfa	41	28	not	not	RB
cord-015935-r2wd1yfa	41	29	be	be	VB
cord-015935-r2wd1yfa	41	30	inherited	inherit	VBN
cord-015935-r2wd1yfa	41	31	in	in	IN
cord-015935-r2wd1yfa	41	32	any	any	DT
cord-015935-r2wd1yfa	41	33	individual	individual	JJ
cord-015935-r2wd1yfa	41	34	case	case	NN
cord-015935-r2wd1yfa	41	35	.	.	.
cord-015935-r2wd1yfa	42	1	Epigenetic	epigenetic	JJ
cord-015935-r2wd1yfa	42	2	variation	variation	NN
cord-015935-r2wd1yfa	42	3	can	can	MD
cord-015935-r2wd1yfa	42	4	significantly	significantly	RB
cord-015935-r2wd1yfa	42	5	alter	alter	VB
cord-015935-r2wd1yfa	42	6	the	the	DT
cord-015935-r2wd1yfa	42	7	expression	expression	NN
cord-015935-r2wd1yfa	42	8	level	level	NN
cord-015935-r2wd1yfa	42	9	of	of	IN
cord-015935-r2wd1yfa	42	10	a	a	DT
cord-015935-r2wd1yfa	42	11	gene	gene	NN
cord-015935-r2wd1yfa	42	12	without	without	IN
cord-015935-r2wd1yfa	42	13	changing	change	VBG
cord-015935-r2wd1yfa	42	14	its	-PRON-	PRP$
cord-015935-r2wd1yfa	42	15	basic	basic	JJ
cord-015935-r2wd1yfa	42	16	genetic	genetic	JJ
cord-015935-r2wd1yfa	42	17	code	code	NN
cord-015935-r2wd1yfa	42	18	.	.	.
cord-015935-r2wd1yfa	43	1	DNA	dna	NN
cord-015935-r2wd1yfa	43	2	replication	replication	NN
cord-015935-r2wd1yfa	43	3	.	.	.
cord-015935-r2wd1yfa	44	1	During	during	IN
cord-015935-r2wd1yfa	44	2	DNA	dna	NN
cord-015935-r2wd1yfa	44	3	replication	replication	NN
cord-015935-r2wd1yfa	44	4	,	,	,
cord-015935-r2wd1yfa	44	5	a	a	DT
cord-015935-r2wd1yfa	44	6	DNA	dna	NN
cord-015935-r2wd1yfa	44	7	strand	strand	NN
cord-015935-r2wd1yfa	44	8	is	be	VBZ
cord-015935-r2wd1yfa	44	9	produced	produce	VBN
cord-015935-r2wd1yfa	44	10	from	from	IN
cord-015935-r2wd1yfa	44	11	component	component	NN
cord-015935-r2wd1yfa	44	12	nucleotides	nucleotide	NNS
cord-015935-r2wd1yfa	44	13	using	use	VBG
cord-015935-r2wd1yfa	44	14	its	-PRON-	PRP$
cord-015935-r2wd1yfa	44	15	partner	partner	NN
cord-015935-r2wd1yfa	44	16	strand	strand	NN
cord-015935-r2wd1yfa	44	17	as	as	IN
cord-015935-r2wd1yfa	44	18	a	a	DT
cord-015935-r2wd1yfa	44	19	template	template	NN
cord-015935-r2wd1yfa	44	20	.	.	.
cord-015935-r2wd1yfa	45	1	This	this	DT
cord-015935-r2wd1yfa	45	2	is	be	VBZ
cord-015935-r2wd1yfa	45	3	done	do	VBN
cord-015935-r2wd1yfa	45	4	by	by	IN
cord-015935-r2wd1yfa	45	5	DNA	dna	NN
cord-015935-r2wd1yfa	45	6	polymerases	polymerase	NNS
cord-015935-r2wd1yfa	45	7	that	that	IN
cord-015935-r2wd1yfa	45	8	"	"	``
cord-015935-r2wd1yfa	45	9	proofread	proofread	VBP
cord-015935-r2wd1yfa	45	10	"	"	''
cord-015935-r2wd1yfa	45	11	to	to	TO
cord-015935-r2wd1yfa	45	12	ensure	ensure	VB
cord-015935-r2wd1yfa	45	13	accuracy	accuracy	NN
cord-015935-r2wd1yfa	45	14	and	and	CC
cord-015935-r2wd1yfa	45	15	repair	repair	NN
cord-015935-r2wd1yfa	45	16	when	when	WRB
cord-015935-r2wd1yfa	45	17	necessary	necessary	JJ
cord-015935-r2wd1yfa	45	18	.	.	.
cord-015935-r2wd1yfa	46	1	Despite	despite	IN
cord-015935-r2wd1yfa	46	2	these	these	DT
cord-015935-r2wd1yfa	46	3	safeguards	safeguard	NNS
cord-015935-r2wd1yfa	46	4	,	,	,
cord-015935-r2wd1yfa	46	5	errors	error	NNS
cord-015935-r2wd1yfa	46	6	called	call	VBN
cord-015935-r2wd1yfa	46	7	mutations	mutation	NNS
cord-015935-r2wd1yfa	46	8	can	can	MD
cord-015935-r2wd1yfa	46	9	occur	occur	VB
cord-015935-r2wd1yfa	46	10	during	during	IN
cord-015935-r2wd1yfa	46	11	the	the	DT
cord-015935-r2wd1yfa	46	12	polymerization	polymerization	NN
cord-015935-r2wd1yfa	46	13	of	of	IN
cord-015935-r2wd1yfa	46	14	this	this	DT
cord-015935-r2wd1yfa	46	15	second	second	JJ
cord-015935-r2wd1yfa	46	16	strand	strand	NN
cord-015935-r2wd1yfa	46	17	.	.	.
cord-015935-r2wd1yfa	47	1	A	a	DT
cord-015935-r2wd1yfa	47	2	mutation	mutation	NN
cord-015935-r2wd1yfa	47	3	is	be	VBZ
cord-015935-r2wd1yfa	47	4	any	any	DT
cord-015935-r2wd1yfa	47	5	nucleotide	nucleotide	JJ
cord-015935-r2wd1yfa	47	6	sequence	sequence	NN
cord-015935-r2wd1yfa	47	7	in	in	IN
cord-015935-r2wd1yfa	47	8	a	a	DT
cord-015935-r2wd1yfa	47	9	DNA	dna	NN
cord-015935-r2wd1yfa	47	10	molecule	molecule	NN
cord-015935-r2wd1yfa	47	11	that	that	WDT
cord-015935-r2wd1yfa	47	12	does	do	VBZ
cord-015935-r2wd1yfa	47	13	not	not	RB
cord-015935-r2wd1yfa	47	14	match	match	VB
cord-015935-r2wd1yfa	47	15	its	-PRON-	PRP$
cord-015935-r2wd1yfa	47	16	original	original	JJ
cord-015935-r2wd1yfa	47	17	DNA	dna	NN
cord-015935-r2wd1yfa	47	18	molecule	molecule	NN
cord-015935-r2wd1yfa	47	19	from	from	IN
cord-015935-r2wd1yfa	47	20	which	which	WDT
cord-015935-r2wd1yfa	47	21	it	-PRON-	PRP
cord-015935-r2wd1yfa	47	22	is	be	VBZ
cord-015935-r2wd1yfa	47	23	copied	copy	VBN
cord-015935-r2wd1yfa	47	24	.	.	.
cord-015935-r2wd1yfa	48	1	Radiation	radiation	NN
cord-015935-r2wd1yfa	48	2	,	,	,
cord-015935-r2wd1yfa	48	3	such	such	JJ
cord-015935-r2wd1yfa	48	4	as	as	IN
cord-015935-r2wd1yfa	48	5	ultraviolet	ultraviolet	JJ
cord-015935-r2wd1yfa	48	6	rays	ray	NNS
cord-015935-r2wd1yfa	48	7	and	and	CC
cord-015935-r2wd1yfa	48	8	X	X	NNS
cord-015935-r2wd1yfa	48	9	-	-	NNS
cord-015935-r2wd1yfa	48	10	rays	ray	NNS
cord-015935-r2wd1yfa	48	11	,	,	,
cord-015935-r2wd1yfa	48	12	viruses	virus	NNS
cord-015935-r2wd1yfa	48	13	,	,	,
cord-015935-r2wd1yfa	48	14	and	and	CC
cord-015935-r2wd1yfa	48	15	errors	error	NNS
cord-015935-r2wd1yfa	48	16	that	that	WDT
cord-015935-r2wd1yfa	48	17	occur	occur	VBP
cord-015935-r2wd1yfa	48	18	during	during	IN
cord-015935-r2wd1yfa	48	19	meiosis	meiosis	NN
cord-015935-r2wd1yfa	48	20	or	or	CC
cord-015935-r2wd1yfa	48	21	during	during	IN
cord-015935-r2wd1yfa	48	22	DNA	dna	NN
cord-015935-r2wd1yfa	48	23	replication	replication	NN
cord-015935-r2wd1yfa	48	24	can	can	MD
cord-015935-r2wd1yfa	48	25	cause	cause	VB
cord-015935-r2wd1yfa	48	26	errors	error	NNS
cord-015935-r2wd1yfa	48	27	in	in	IN
cord-015935-r2wd1yfa	48	28	DNA	dna	NN
cord-015935-r2wd1yfa	48	29	molecules	molecule	NNS
cord-015935-r2wd1yfa	48	30	.	.	.
cord-015935-r2wd1yfa	49	1	These	these	DT
cord-015935-r2wd1yfa	49	2	mutations	mutation	NNS
cord-015935-r2wd1yfa	49	3	can	can	MD
cord-015935-r2wd1yfa	49	4	have	have	VB
cord-015935-r2wd1yfa	49	5	an	an	DT
cord-015935-r2wd1yfa	49	6	impact	impact	NN
cord-015935-r2wd1yfa	49	7	on	on	IN
cord-015935-r2wd1yfa	49	8	the	the	DT
cord-015935-r2wd1yfa	49	9	phenotype	phenotype	NN
cord-015935-r2wd1yfa	49	10	of	of	IN
cord-015935-r2wd1yfa	49	11	an	an	DT
cord-015935-r2wd1yfa	49	12	organism	organism	NN
cord-015935-r2wd1yfa	49	13	,	,	,
cord-015935-r2wd1yfa	49	14	especially	especially	RB
cord-015935-r2wd1yfa	49	15	when	when	WRB
cord-015935-r2wd1yfa	49	16	they	-PRON-	PRP
cord-015935-r2wd1yfa	49	17	occur	occur	VBP
cord-015935-r2wd1yfa	49	18	within	within	IN
cord-015935-r2wd1yfa	49	19	the	the	DT
cord-015935-r2wd1yfa	49	20	protein	protein	NN
cord-015935-r2wd1yfa	49	21	-	-	HYPH
cord-015935-r2wd1yfa	49	22	coding	code	VBG
cord-015935-r2wd1yfa	49	23	sequence	sequence	NN
cord-015935-r2wd1yfa	49	24	of	of	IN
cord-015935-r2wd1yfa	49	25	the	the	DT
cord-015935-r2wd1yfa	49	26	gene	gene	NN
cord-015935-r2wd1yfa	49	27	.	.	.
cord-015935-r2wd1yfa	50	1	Kinds	kind	NNS
cord-015935-r2wd1yfa	50	2	of	of	IN
cord-015935-r2wd1yfa	50	3	mutations	mutation	NNS
cord-015935-r2wd1yfa	50	4	include	include	VBP
cord-015935-r2wd1yfa	50	5	the	the	DT
cord-015935-r2wd1yfa	50	6	following	follow	VBG
cord-015935-r2wd1yfa	50	7	:	:	:
cord-015935-r2wd1yfa	50	8	Frameshift	Frameshift	NNP
cord-015935-r2wd1yfa	50	9	Mutation	Mutation	NNP
cord-015935-r2wd1yfa	50	10	:	:	:
cord-015935-r2wd1yfa	51	1	One	one	CD
cord-015935-r2wd1yfa	51	2	or	or	CC
cord-015935-r2wd1yfa	51	3	more	more	JJR
cord-015935-r2wd1yfa	51	4	bases	basis	NNS
cord-015935-r2wd1yfa	51	5	are	be	VBP
cord-015935-r2wd1yfa	51	6	inserted	insert	VBN
cord-015935-r2wd1yfa	51	7	or	or	CC
cord-015935-r2wd1yfa	51	8	deleted	delete	VBN
cord-015935-r2wd1yfa	51	9	.	.	.
cord-015935-r2wd1yfa	52	1	This	this	DT
cord-015935-r2wd1yfa	52	2	can	can	MD
cord-015935-r2wd1yfa	52	3	alter	alter	VB
cord-015935-r2wd1yfa	52	4	the	the	DT
cord-015935-r2wd1yfa	52	5	entire	entire	JJ
cord-015935-r2wd1yfa	52	6	amino	amino	NN
cord-015935-r2wd1yfa	52	7	acid	acid	NN
cord-015935-r2wd1yfa	52	8	sequence	sequence	NN
cord-015935-r2wd1yfa	52	9	of	of	IN
cord-015935-r2wd1yfa	52	10	a	a	DT
cord-015935-r2wd1yfa	52	11	protein	protein	NN
cord-015935-r2wd1yfa	52	12	or	or	CC
cord-015935-r2wd1yfa	52	13	introduce	introduce	VB
cord-015935-r2wd1yfa	52	14	aberrant	aberrant	JJ
cord-015935-r2wd1yfa	52	15	RNA	RNA	NNP
cord-015935-r2wd1yfa	52	16	splicing	splicing	NN
cord-015935-r2wd1yfa	52	17	.	.	.
cord-015935-r2wd1yfa	53	1	Deletion	deletion	NN
cord-015935-r2wd1yfa	53	2	.	.	.
cord-015935-r2wd1yfa	54	1	Missing	miss	VBG
cord-015935-r2wd1yfa	54	2	DNA	dna	NN
cord-015935-r2wd1yfa	54	3	sequences	sequence	NNS
cord-015935-r2wd1yfa	54	4	can	can	MD
cord-015935-r2wd1yfa	54	5	range	range	VB
cord-015935-r2wd1yfa	54	6	from	from	IN
cord-015935-r2wd1yfa	54	7	a	a	DT
cord-015935-r2wd1yfa	54	8	single	single	JJ
cord-015935-r2wd1yfa	54	9	base	base	NN
cord-015935-r2wd1yfa	54	10	pair	pair	NN
cord-015935-r2wd1yfa	54	11	to	to	IN
cord-015935-r2wd1yfa	54	12	longer	long	JJR
cord-015935-r2wd1yfa	54	13	deletions	deletion	NNS
cord-015935-r2wd1yfa	54	14	involving	involve	VBG
cord-015935-r2wd1yfa	54	15	many	many	JJ
cord-015935-r2wd1yfa	54	16	genes	gene	NNS
cord-015935-r2wd1yfa	54	17	in	in	IN
cord-015935-r2wd1yfa	54	18	the	the	DT
cord-015935-r2wd1yfa	54	19	chromosome	chromosome	NN
cord-015935-r2wd1yfa	54	20	.	.	.
cord-015935-r2wd1yfa	55	1	Insertion	insertion	NN
cord-015935-r2wd1yfa	55	2	.	.	.
cord-015935-r2wd1yfa	56	1	Additional	additional	JJ
cord-015935-r2wd1yfa	56	2	nucleotides	nucleotide	NNS
cord-015935-r2wd1yfa	56	3	are	be	VBP
cord-015935-r2wd1yfa	56	4	inserted	insert	VBN
cord-015935-r2wd1yfa	56	5	in	in	IN
cord-015935-r2wd1yfa	56	6	the	the	DT
cord-015935-r2wd1yfa	56	7	DNA	dna	NN
cord-015935-r2wd1yfa	56	8	sequence	sequence	NN
cord-015935-r2wd1yfa	56	9	and	and	CC
cord-015935-r2wd1yfa	56	10	can	can	MD
cord-015935-r2wd1yfa	56	11	result	result	VB
cord-015935-r2wd1yfa	56	12	in	in	IN
cord-015935-r2wd1yfa	56	13	a	a	DT
cord-015935-r2wd1yfa	56	14	nonfunctional	nonfunctional	JJ
cord-015935-r2wd1yfa	56	15	protein	protein	NN
cord-015935-r2wd1yfa	56	16	.	.	.
cord-015935-r2wd1yfa	57	1	Duplication	duplication	NN
cord-015935-r2wd1yfa	57	2	(	(	-LRB-
cord-015935-r2wd1yfa	57	3	or	or	CC
cord-015935-r2wd1yfa	57	4	gene	gene	NN
cord-015935-r2wd1yfa	57	5	amplification	amplification	NN
cord-015935-r2wd1yfa	57	6	)	)	-RRB-
cord-015935-r2wd1yfa	57	7	.	.	.
cord-015935-r2wd1yfa	58	1	Multiple	multiple	JJ
cord-015935-r2wd1yfa	58	2	copies	copy	NNS
cord-015935-r2wd1yfa	58	3	of	of	IN
cord-015935-r2wd1yfa	58	4	a	a	DT
cord-015935-r2wd1yfa	58	5	complete	complete	JJ
cord-015935-r2wd1yfa	58	6	gene	gene	NN
cord-015935-r2wd1yfa	58	7	or	or	CC
cord-015935-r2wd1yfa	58	8	genes	gene	NNS
cord-015935-r2wd1yfa	58	9	,	,	,
cord-015935-r2wd1yfa	58	10	increasing	increase	VBG
cord-015935-r2wd1yfa	58	11	the	the	DT
cord-015935-r2wd1yfa	58	12	dosage	dosage	NN
cord-015935-r2wd1yfa	58	13	of	of	IN
cord-015935-r2wd1yfa	58	14	genes	gene	NNS
cord-015935-r2wd1yfa	58	15	located	locate	VBN
cord-015935-r2wd1yfa	58	16	within	within	IN
cord-015935-r2wd1yfa	58	17	chromosomes	chromosome	NNS
cord-015935-r2wd1yfa	58	18	.	.	.
cord-015935-r2wd1yfa	59	1	Inversion	inversion	NN
cord-015935-r2wd1yfa	59	2	.	.	.
cord-015935-r2wd1yfa	60	1	DNA	dna	NN
cord-015935-r2wd1yfa	60	2	sequence	sequence	NN
cord-015935-r2wd1yfa	60	3	of	of	IN
cord-015935-r2wd1yfa	60	4	nucleotides	nucleotide	NNS
cord-015935-r2wd1yfa	60	5	is	be	VBZ
cord-015935-r2wd1yfa	60	6	reversed	reverse	VBN
cord-015935-r2wd1yfa	60	7	,	,	,
cord-015935-r2wd1yfa	60	8	either	either	CC
cord-015935-r2wd1yfa	60	9	among	among	IN
cord-015935-r2wd1yfa	60	10	a	a	DT
cord-015935-r2wd1yfa	60	11	few	few	JJ
cord-015935-r2wd1yfa	60	12	bases	basis	NNS
cord-015935-r2wd1yfa	60	13	within	within	IN
cord-015935-r2wd1yfa	60	14	one	one	CD
cord-015935-r2wd1yfa	60	15	gene	gene	NN
cord-015935-r2wd1yfa	60	16	or	or	CC
cord-015935-r2wd1yfa	60	17	among	among	IN
cord-015935-r2wd1yfa	60	18	longer	long	JJR
cord-015935-r2wd1yfa	60	19	DNA	dna	NN
cord-015935-r2wd1yfa	60	20	sequences	sequence	NNS
cord-015935-r2wd1yfa	60	21	containing	contain	VBG
cord-015935-r2wd1yfa	60	22	several	several	JJ
cord-015935-r2wd1yfa	60	23	genes	gene	NNS
cord-015935-r2wd1yfa	60	24	.	.	.
cord-015935-r2wd1yfa	61	1	Point	point	NN
cord-015935-r2wd1yfa	61	2	mutations	mutation	NNS
cord-015935-r2wd1yfa	61	3	.	.	.
cord-015935-r2wd1yfa	62	1	Known	know	VBN
cord-015935-r2wd1yfa	62	2	as	as	IN
cord-015935-r2wd1yfa	62	3	substitutions	substitution	NNS
cord-015935-r2wd1yfa	62	4	,	,	,
cord-015935-r2wd1yfa	62	5	this	this	DT
cord-015935-r2wd1yfa	62	6	is	be	VBZ
cord-015935-r2wd1yfa	62	7	a	a	DT
cord-015935-r2wd1yfa	62	8	replacement	replacement	NN
cord-015935-r2wd1yfa	62	9	of	of	IN
cord-015935-r2wd1yfa	62	10	a	a	DT
cord-015935-r2wd1yfa	62	11	single	single	JJ
cord-015935-r2wd1yfa	62	12	base	base	NN
cord-015935-r2wd1yfa	62	13	nucleotide	nucleotide	JJ
cord-015935-r2wd1yfa	62	14	with	with	IN
cord-015935-r2wd1yfa	62	15	another	another	DT
cord-015935-r2wd1yfa	62	16	nucleotide	nucleotide	NN
cord-015935-r2wd1yfa	62	17	.	.	.
cord-015935-r2wd1yfa	63	1	Missense	missense	NN
cord-015935-r2wd1yfa	63	2	mutations	mutation	NNS
cord-015935-r2wd1yfa	63	3	.	.	.
cord-015935-r2wd1yfa	64	1	A	a	DT
cord-015935-r2wd1yfa	64	2	point	point	NN
cord-015935-r2wd1yfa	64	3	mutation	mutation	NN
cord-015935-r2wd1yfa	64	4	where	where	WRB
cord-015935-r2wd1yfa	64	5	a	a	DT
cord-015935-r2wd1yfa	64	6	single	single	JJ
cord-015935-r2wd1yfa	64	7	nucleotide	nucleotide	NN
cord-015935-r2wd1yfa	64	8	is	be	VBZ
cord-015935-r2wd1yfa	64	9	changed	change	VBN
cord-015935-r2wd1yfa	64	10	to	to	TO
cord-015935-r2wd1yfa	64	11	cause	cause	VB
cord-015935-r2wd1yfa	64	12	substitution	substitution	NN
cord-015935-r2wd1yfa	64	13	of	of	IN
cord-015935-r2wd1yfa	64	14	a	a	DT
cord-015935-r2wd1yfa	64	15	different	different	JJ
cord-015935-r2wd1yfa	64	16	amino	amino	NN
cord-015935-r2wd1yfa	64	17	acid	acid	NN
cord-015935-r2wd1yfa	64	18	.	.	.
cord-015935-r2wd1yfa	65	1	Nonsense	nonsense	NN
cord-015935-r2wd1yfa	65	2	mutation	mutation	NN
cord-015935-r2wd1yfa	65	3	.	.	.
cord-015935-r2wd1yfa	66	1	A	a	DT
cord-015935-r2wd1yfa	66	2	point	point	NN
cord-015935-r2wd1yfa	66	3	mutation	mutation	NN
cord-015935-r2wd1yfa	66	4	that	that	WDT
cord-015935-r2wd1yfa	66	5	results	result	VBZ
cord-015935-r2wd1yfa	66	6	in	in	IN
cord-015935-r2wd1yfa	66	7	a	a	DT
cord-015935-r2wd1yfa	66	8	premature	premature	JJ
cord-015935-r2wd1yfa	66	9	stop	stop	NN
cord-015935-r2wd1yfa	66	10	codon	codon	NN
cord-015935-r2wd1yfa	66	11	in	in	IN
cord-015935-r2wd1yfa	66	12	the	the	DT
cord-015935-r2wd1yfa	66	13	transcribed	transcribe	VBN
cord-015935-r2wd1yfa	66	14	mRNA	mrna	NN
cord-015935-r2wd1yfa	66	15	and	and	CC
cord-015935-r2wd1yfa	66	16	possibly	possibly	RB
cord-015935-r2wd1yfa	66	17	a	a	DT
cord-015935-r2wd1yfa	66	18	nonfunctional	nonfunctional	JJ
cord-015935-r2wd1yfa	66	19	protein	protein	NN
cord-015935-r2wd1yfa	66	20	product	product	NN
cord-015935-r2wd1yfa	66	21	.	.	.
cord-015935-r2wd1yfa	67	1	RNA	RNA	NNP
cord-015935-r2wd1yfa	67	2	splicing	splicing	NN
cord-015935-r2wd1yfa	67	3	mutation	mutation	NN
cord-015935-r2wd1yfa	67	4	.	.	.
cord-015935-r2wd1yfa	68	1	A	a	DT
cord-015935-r2wd1yfa	68	2	point	point	NN
cord-015935-r2wd1yfa	68	3	mutation	mutation	NN
cord-015935-r2wd1yfa	68	4	that	that	WDT
cord-015935-r2wd1yfa	68	5	inserts	insert	VBZ
cord-015935-r2wd1yfa	68	6	or	or	CC
cord-015935-r2wd1yfa	68	7	deletes	delete	VBZ
cord-015935-r2wd1yfa	68	8	an	an	DT
cord-015935-r2wd1yfa	68	9	intron	intron	NN
cord-015935-r2wd1yfa	68	10	/	/	SYM
cord-015935-r2wd1yfa	68	11	exon	exon	NN
cord-015935-r2wd1yfa	68	12	border	border	NN
cord-015935-r2wd1yfa	68	13	necessary	necessary	JJ
cord-015935-r2wd1yfa	68	14	for	for	IN
cord-015935-r2wd1yfa	68	15	splicing	splicing	NN
cord-015935-r2wd1yfa	68	16	of	of	IN
cord-015935-r2wd1yfa	68	17	heterogeneous	heterogeneous	JJ
cord-015935-r2wd1yfa	68	18	nuclear	nuclear	JJ
cord-015935-r2wd1yfa	68	19	RNA	RNA	NNP
cord-015935-r2wd1yfa	68	20	to	to	IN
cord-015935-r2wd1yfa	68	21	mRNA	mRNA	NNP
cord-015935-r2wd1yfa	68	22	.	.	.
cord-015935-r2wd1yfa	69	1	Silent	silent	JJ
cord-015935-r2wd1yfa	69	2	mutation	mutation	NN
cord-015935-r2wd1yfa	69	3	.	.	.
cord-015935-r2wd1yfa	70	1	A	a	DT
cord-015935-r2wd1yfa	70	2	point	point	NN
cord-015935-r2wd1yfa	70	3	mutation	mutation	NN
cord-015935-r2wd1yfa	70	4	that	that	WDT
cord-015935-r2wd1yfa	70	5	does	do	VBZ
cord-015935-r2wd1yfa	70	6	not	not	RB
cord-015935-r2wd1yfa	70	7	alter	alter	VB
cord-015935-r2wd1yfa	70	8	the	the	DT
cord-015935-r2wd1yfa	70	9	amino	amino	NN
cord-015935-r2wd1yfa	70	10	acid	acid	NN
cord-015935-r2wd1yfa	70	11	coding	code	VBG
cord-015935-r2wd1yfa	70	12	for	for	IN
cord-015935-r2wd1yfa	70	13	that	that	DT
cord-015935-r2wd1yfa	70	14	codon	codon	NN
cord-015935-r2wd1yfa	70	15	.	.	.
cord-015935-r2wd1yfa	71	1	Gene	gene	NN
cord-015935-r2wd1yfa	71	2	expression	expression	NN
cord-015935-r2wd1yfa	71	3	is	be	VBZ
cord-015935-r2wd1yfa	71	4	the	the	DT
cord-015935-r2wd1yfa	71	5	process	process	NN
cord-015935-r2wd1yfa	71	6	in	in	IN
cord-015935-r2wd1yfa	71	7	which	which	WDT
cord-015935-r2wd1yfa	71	8	genes	gene	NNS
cord-015935-r2wd1yfa	71	9	express	express	VBP
cord-015935-r2wd1yfa	71	10	their	-PRON-	PRP$
cord-015935-r2wd1yfa	71	11	functional	functional	JJ
cord-015935-r2wd1yfa	71	12	effect	effect	NN
cord-015935-r2wd1yfa	71	13	through	through	IN
cord-015935-r2wd1yfa	71	14	the	the	DT
cord-015935-r2wd1yfa	71	15	production	production	NN
cord-015935-r2wd1yfa	71	16	of	of	IN
cord-015935-r2wd1yfa	71	17	proteins	protein	NNS
cord-015935-r2wd1yfa	71	18	which	which	WDT
cord-015935-r2wd1yfa	71	19	are	be	VBP
cord-015935-r2wd1yfa	71	20	responsible	responsible	JJ
cord-015935-r2wd1yfa	71	21	for	for	IN
cord-015935-r2wd1yfa	71	22	most	most	JJS
cord-015935-r2wd1yfa	71	23	functions	function	NNS
cord-015935-r2wd1yfa	71	24	of	of	IN
cord-015935-r2wd1yfa	71	25	the	the	DT
cord-015935-r2wd1yfa	71	26	cell	cell	NN
cord-015935-r2wd1yfa	71	27	.	.	.
cord-015935-r2wd1yfa	72	1	The	the	DT
cord-015935-r2wd1yfa	72	2	DNA	dna	NN
cord-015935-r2wd1yfa	72	3	sequence	sequence	NN
cord-015935-r2wd1yfa	72	4	of	of	IN
cord-015935-r2wd1yfa	72	5	a	a	DT
cord-015935-r2wd1yfa	72	6	gene	gene	NN
cord-015935-r2wd1yfa	72	7	is	be	VBZ
cord-015935-r2wd1yfa	72	8	used	use	VBN
cord-015935-r2wd1yfa	72	9	to	to	TO
cord-015935-r2wd1yfa	72	10	produce	produce	VB
cord-015935-r2wd1yfa	72	11	a	a	DT
cord-015935-r2wd1yfa	72	12	specific	specific	JJ
cord-015935-r2wd1yfa	72	13	protein	protein	NN
cord-015935-r2wd1yfa	72	14	through	through	IN
cord-015935-r2wd1yfa	72	15	a	a	DT
cord-015935-r2wd1yfa	72	16	ribose	ribose	NN
cord-015935-r2wd1yfa	72	17	nucleic	nucleic	JJ
cord-015935-r2wd1yfa	72	18	acid	acid	NN
cord-015935-r2wd1yfa	72	19	(	(	-LRB-
cord-015935-r2wd1yfa	72	20	RNA	RNA	NNP
cord-015935-r2wd1yfa	72	21	)	)	-RRB-
cord-015935-r2wd1yfa	72	22	intermediate	intermediate	NN
cord-015935-r2wd1yfa	72	23	.	.	.
cord-015935-r2wd1yfa	73	1	Gene	gene	NN
cord-015935-r2wd1yfa	73	2	DNA	DNA	NNP
cord-015935-r2wd1yfa	73	3	is	be	VBZ
cord-015935-r2wd1yfa	73	4	the	the	DT
cord-015935-r2wd1yfa	73	5	map	map	NN
cord-015935-r2wd1yfa	73	6	which	which	WDT
cord-015935-r2wd1yfa	73	7	directs	direct	VBZ
cord-015935-r2wd1yfa	73	8	the	the	DT
cord-015935-r2wd1yfa	73	9	production	production	NN
cord-015935-r2wd1yfa	73	10	of	of	IN
cord-015935-r2wd1yfa	73	11	the	the	DT
cord-015935-r2wd1yfa	73	12	protein	protein	NN
cord-015935-r2wd1yfa	73	13	,	,	,
cord-015935-r2wd1yfa	73	14	normally	normally	RB
cord-015935-r2wd1yfa	73	15	following	follow	VBG
cord-015935-r2wd1yfa	73	16	a	a	DT
cord-015935-r2wd1yfa	73	17	one	one	CD
cord-015935-r2wd1yfa	73	18	-	-	HYPH
cord-015935-r2wd1yfa	73	19	way	way	NN
cord-015935-r2wd1yfa	73	20	pathway	pathway	NN
cord-015935-r2wd1yfa	73	21	:	:	:
cord-015935-r2wd1yfa	74	1	Splicing	Splicing	NNP
cord-015935-r2wd1yfa	74	2	Translation	Translation	NNP
cord-015935-r2wd1yfa	74	3	Gene	Gene	NNP
cord-015935-r2wd1yfa	74	4	regulation	regulation	NN
cord-015935-r2wd1yfa	74	5	gives	give	VBZ
cord-015935-r2wd1yfa	74	6	the	the	DT
cord-015935-r2wd1yfa	74	7	cell	cell	NN
cord-015935-r2wd1yfa	74	8	control	control	NN
cord-015935-r2wd1yfa	74	9	over	over	IN
cord-015935-r2wd1yfa	74	10	structure	structure	NN
cord-015935-r2wd1yfa	74	11	and	and	CC
cord-015935-r2wd1yfa	74	12	function	function	NN
cord-015935-r2wd1yfa	74	13	and	and	CC
cord-015935-r2wd1yfa	74	14	is	be	VBZ
cord-015935-r2wd1yfa	74	15	the	the	DT
cord-015935-r2wd1yfa	74	16	basis	basis	NN
cord-015935-r2wd1yfa	74	17	for	for	IN
cord-015935-r2wd1yfa	74	18	cellular	cellular	JJ
cord-015935-r2wd1yfa	74	19	differentiation	differentiation	NN
cord-015935-r2wd1yfa	74	20	and	and	CC
cord-015935-r2wd1yfa	74	21	adaptability	adaptability	NN
cord-015935-r2wd1yfa	74	22	of	of	IN
cord-015935-r2wd1yfa	74	23	any	any	DT
cord-015935-r2wd1yfa	74	24	organism	organism	NN
cord-015935-r2wd1yfa	74	25	.	.	.
cord-015935-r2wd1yfa	75	1	Gene	gene	NN
cord-015935-r2wd1yfa	75	2	regulation	regulation	NN
cord-015935-r2wd1yfa	75	3	is	be	VBZ
cord-015935-r2wd1yfa	75	4	controlled	control	VBN
cord-015935-r2wd1yfa	75	5	by	by	IN
cord-015935-r2wd1yfa	75	6	noncoding	noncoding	JJ
cord-015935-r2wd1yfa	75	7	DNA	dna	NN
cord-015935-r2wd1yfa	75	8	sequences	sequence	NNS
cord-015935-r2wd1yfa	75	9	,	,	,
cord-015935-r2wd1yfa	75	10	such	such	JJ
cord-015935-r2wd1yfa	75	11	as	as	IN
cord-015935-r2wd1yfa	75	12	the	the	DT
cord-015935-r2wd1yfa	75	13	promoter	promoter	NN
cord-015935-r2wd1yfa	75	14	,	,	,
cord-015935-r2wd1yfa	75	15	terminator	terminator	NNP
cord-015935-r2wd1yfa	75	16	,	,	,
cord-015935-r2wd1yfa	75	17	or	or	CC
cord-015935-r2wd1yfa	75	18	introns	intron	NNS
cord-015935-r2wd1yfa	75	19	,	,	,
cord-015935-r2wd1yfa	75	20	and	and	CC
cord-015935-r2wd1yfa	75	21	by	by	IN
cord-015935-r2wd1yfa	75	22	epigenetic	epigenetic	JJ
cord-015935-r2wd1yfa	75	23	variation	variation	NN
cord-015935-r2wd1yfa	75	24	,	,	,
cord-015935-r2wd1yfa	75	25	such	such	JJ
cord-015935-r2wd1yfa	75	26	as	as	IN
cord-015935-r2wd1yfa	75	27	differences	difference	NNS
cord-015935-r2wd1yfa	75	28	in	in	IN
cord-015935-r2wd1yfa	75	29	DNA	dna	NN
cord-015935-r2wd1yfa	75	30	methylation	methylation	NN
cord-015935-r2wd1yfa	75	31	and	and	CC
cord-015935-r2wd1yfa	75	32	histone	histone	NN
cord-015935-r2wd1yfa	75	33	acetylation	acetylation	NN
cord-015935-r2wd1yfa	75	34	.	.	.
cord-015935-r2wd1yfa	76	1	This	this	DT
cord-015935-r2wd1yfa	76	2	entire	entire	JJ
cord-015935-r2wd1yfa	76	3	process	process	NN
cord-015935-r2wd1yfa	76	4	takes	take	VBZ
cord-015935-r2wd1yfa	76	5	place	place	NN
cord-015935-r2wd1yfa	76	6	within	within	IN
cord-015935-r2wd1yfa	76	7	the	the	DT
cord-015935-r2wd1yfa	76	8	cell	cell	NN
cord-015935-r2wd1yfa	76	9	in	in	IN
cord-015935-r2wd1yfa	76	10	the	the	DT
cord-015935-r2wd1yfa	76	11	vicinity	vicinity	NN
cord-015935-r2wd1yfa	76	12	of	of	IN
cord-015935-r2wd1yfa	76	13	the	the	DT
cord-015935-r2wd1yfa	76	14	nucleus	nucleus	NN
cord-015935-r2wd1yfa	76	15	,	,	,
cord-015935-r2wd1yfa	76	16	where	where	WRB
cord-015935-r2wd1yfa	76	17	DNA	DNA	NNP
cord-015935-r2wd1yfa	76	18	is	be	VBZ
cord-015935-r2wd1yfa	76	19	housed	house	VBN
cord-015935-r2wd1yfa	76	20	and	and	CC
cord-015935-r2wd1yfa	76	21	hnRNA	hnrna	NN
cord-015935-r2wd1yfa	76	22	is	be	VBZ
cord-015935-r2wd1yfa	76	23	spliced	splice	VBN
cord-015935-r2wd1yfa	76	24	,	,	,
cord-015935-r2wd1yfa	76	25	and	and	CC
cord-015935-r2wd1yfa	76	26	in	in	IN
cord-015935-r2wd1yfa	76	27	the	the	DT
cord-015935-r2wd1yfa	76	28	cytoplasm	cytoplasm	NN
cord-015935-r2wd1yfa	76	29	,	,	,
cord-015935-r2wd1yfa	76	30	where	where	WRB
cord-015935-r2wd1yfa	76	31	ribosomes	ribosome	NNS
cord-015935-r2wd1yfa	76	32	are	be	VBP
cord-015935-r2wd1yfa	76	33	located	locate	VBN
cord-015935-r2wd1yfa	76	34	along	along	IN
cord-015935-r2wd1yfa	76	35	the	the	DT
cord-015935-r2wd1yfa	76	36	rough	rough	JJ
cord-015935-r2wd1yfa	76	37	endoplasmic	endoplasmic	NN
cord-015935-r2wd1yfa	76	38	reticulum	reticulum	NN
cord-015935-r2wd1yfa	76	39	.	.	.
cord-015935-r2wd1yfa	77	1	Some	some	DT
cord-015935-r2wd1yfa	77	2	proteins	protein	NNS
cord-015935-r2wd1yfa	77	3	are	be	VBP
cord-015935-r2wd1yfa	77	4	further	further	RB
cord-015935-r2wd1yfa	77	5	processed	process	VBN
cord-015935-r2wd1yfa	77	6	in	in	IN
cord-015935-r2wd1yfa	77	7	the	the	DT
cord-015935-r2wd1yfa	77	8	Golgi	Golgi	NNP
cord-015935-r2wd1yfa	77	9	apparatus	apparatus	NN
cord-015935-r2wd1yfa	77	10	if	if	IN
cord-015935-r2wd1yfa	77	11	they	-PRON-	PRP
cord-015935-r2wd1yfa	77	12	are	be	VBP
cord-015935-r2wd1yfa	77	13	to	to	TO
cord-015935-r2wd1yfa	77	14	be	be	VB
cord-015935-r2wd1yfa	77	15	exported	export	VBN
cord-015935-r2wd1yfa	77	16	from	from	IN
cord-015935-r2wd1yfa	77	17	the	the	DT
cord-015935-r2wd1yfa	77	18	cell	cell	NN
cord-015935-r2wd1yfa	77	19	.	.	.
cord-015935-r2wd1yfa	78	1	The	the	DT
cord-015935-r2wd1yfa	78	2	correspondence	correspondence	NN
cord-015935-r2wd1yfa	78	3	between	between	IN
cord-015935-r2wd1yfa	78	4	nucleotide	nucleotide	JJ
cord-015935-r2wd1yfa	78	5	and	and	CC
cord-015935-r2wd1yfa	78	6	amino	amino	NN
cord-015935-r2wd1yfa	78	7	acid	acid	NN
cord-015935-r2wd1yfa	78	8	sequence	sequence	NN
cord-015935-r2wd1yfa	78	9	is	be	VBZ
cord-015935-r2wd1yfa	78	10	known	know	VBN
cord-015935-r2wd1yfa	78	11	as	as	IN
cord-015935-r2wd1yfa	78	12	the	the	DT
cord-015935-r2wd1yfa	78	13	genetic	genetic	JJ
cord-015935-r2wd1yfa	78	14	code	code	NN
cord-015935-r2wd1yfa	78	15	.	.	.
cord-015935-r2wd1yfa	79	1	RNA	RNA	NNP
cord-015935-r2wd1yfa	79	2	transcription	transcription	NN
cord-015935-r2wd1yfa	79	3	.	.	.
cord-015935-r2wd1yfa	80	1	In	in	IN
cord-015935-r2wd1yfa	80	2	transcription	transcription	NN
cord-015935-r2wd1yfa	80	3	,	,	,
cord-015935-r2wd1yfa	80	4	DNA	DNA	NNP
cord-015935-r2wd1yfa	80	5	is	be	VBZ
cord-015935-r2wd1yfa	80	6	used	use	VBN
cord-015935-r2wd1yfa	80	7	as	as	IN
cord-015935-r2wd1yfa	80	8	a	a	DT
cord-015935-r2wd1yfa	80	9	blueprint	blueprint	NN
cord-015935-r2wd1yfa	80	10	for	for	IN
cord-015935-r2wd1yfa	80	11	the	the	DT
cord-015935-r2wd1yfa	80	12	production	production	NN
cord-015935-r2wd1yfa	80	13	of	of	IN
cord-015935-r2wd1yfa	80	14	RNA	RNA	NNP
cord-015935-r2wd1yfa	80	15	.	.	.
cord-015935-r2wd1yfa	81	1	Transcription	transcription	NN
cord-015935-r2wd1yfa	81	2	is	be	VBZ
cord-015935-r2wd1yfa	81	3	performed	perform	VBN
cord-015935-r2wd1yfa	81	4	by	by	IN
cord-015935-r2wd1yfa	81	5	RNA	RNA	NNP
cord-015935-r2wd1yfa	81	6	polymerase	polymerase	NN
cord-015935-r2wd1yfa	81	7	which	which	WDT
cord-015935-r2wd1yfa	81	8	adds	add	VBZ
cord-015935-r2wd1yfa	81	9	one	one	CD
cord-015935-r2wd1yfa	81	10	ribonucleotide	ribonucleotide	NN
cord-015935-r2wd1yfa	81	11	to	to	IN
cord-015935-r2wd1yfa	81	12	a	a	DT
cord-015935-r2wd1yfa	81	13	growing	grow	VBG
cord-015935-r2wd1yfa	81	14	RNA	RNA	NNP
cord-015935-r2wd1yfa	81	15	strand	strand	NN
cord-015935-r2wd1yfa	81	16	,	,	,
cord-015935-r2wd1yfa	81	17	complimentary	complimentary	JJ
cord-015935-r2wd1yfa	81	18	to	to	IN
cord-015935-r2wd1yfa	81	19	the	the	DT
cord-015935-r2wd1yfa	81	20	DNA	dna	NN
cord-015935-r2wd1yfa	81	21	nucleotide	nucleotide	NN
cord-015935-r2wd1yfa	81	22	being	be	VBG
cord-015935-r2wd1yfa	81	23	transcribed	transcribe	VBN
cord-015935-r2wd1yfa	81	24	.	.	.
cord-015935-r2wd1yfa	82	1	This	this	DT
cord-015935-r2wd1yfa	82	2	product	product	NN
cord-015935-r2wd1yfa	82	3	is	be	VBZ
cord-015935-r2wd1yfa	82	4	heterologous	heterologous	NNP
cord-015935-r2wd1yfa	82	5	nuclear	nuclear	NNP
cord-015935-r2wd1yfa	82	6	RNA	RNA	NNP
cord-015935-r2wd1yfa	82	7	(	(	-LRB-
cord-015935-r2wd1yfa	82	8	hnRNA	hnrna	NN
cord-015935-r2wd1yfa	82	9	)	)	-RRB-
cord-015935-r2wd1yfa	82	10	.	.	.
cord-015935-r2wd1yfa	83	1	RNA	RNA	NNP
cord-015935-r2wd1yfa	83	2	splicing	splicing	NN
cord-015935-r2wd1yfa	83	3	.	.	.
cord-015935-r2wd1yfa	84	1	In	in	IN
cord-015935-r2wd1yfa	84	2	splicing	splicing	NN
cord-015935-r2wd1yfa	84	3	,	,	,
cord-015935-r2wd1yfa	84	4	hnRNA	hnrna	ADD
cord-015935-r2wd1yfa	84	5	is	be	VBZ
cord-015935-r2wd1yfa	84	6	processed	process	VBN
cord-015935-r2wd1yfa	84	7	within	within	IN
cord-015935-r2wd1yfa	84	8	the	the	DT
cord-015935-r2wd1yfa	84	9	nucleus	nucleus	NN
cord-015935-r2wd1yfa	84	10	to	to	TO
cord-015935-r2wd1yfa	84	11	remove	remove	VB
cord-015935-r2wd1yfa	84	12	introns	intron	NNS
cord-015935-r2wd1yfa	84	13	which	which	WDT
cord-015935-r2wd1yfa	84	14	may	may	MD
cord-015935-r2wd1yfa	84	15	function	function	VB
cord-015935-r2wd1yfa	84	16	to	to	TO
cord-015935-r2wd1yfa	84	17	partially	partially	RB
cord-015935-r2wd1yfa	84	18	regulate	regulate	VB
cord-015935-r2wd1yfa	84	19	transcription	transcription	NN
cord-015935-r2wd1yfa	84	20	and	and	CC
cord-015935-r2wd1yfa	84	21	join	join	VB
cord-015935-r2wd1yfa	84	22	exons	exon	NNS
cord-015935-r2wd1yfa	84	23	,	,	,
cord-015935-r2wd1yfa	84	24	which	which	WDT
cord-015935-r2wd1yfa	84	25	code	code	NN
cord-015935-r2wd1yfa	84	26	for	for	IN
cord-015935-r2wd1yfa	84	27	the	the	DT
cord-015935-r2wd1yfa	84	28	actual	actual	JJ
cord-015935-r2wd1yfa	84	29	protein	protein	NN
cord-015935-r2wd1yfa	84	30	product	product	NN
cord-015935-r2wd1yfa	84	31	.	.	.
cord-015935-r2wd1yfa	85	1	The	the	DT
cord-015935-r2wd1yfa	85	2	product	product	NN
cord-015935-r2wd1yfa	85	3	of	of	IN
cord-015935-r2wd1yfa	85	4	slicing	slicing	NN
cord-015935-r2wd1yfa	85	5	is	be	VBZ
cord-015935-r2wd1yfa	85	6	mRNA	mrna	NN
cord-015935-r2wd1yfa	85	7	.	.	.
cord-015935-r2wd1yfa	86	1	Translation	translation	NN
cord-015935-r2wd1yfa	86	2	.	.	.
cord-015935-r2wd1yfa	87	1	Translation	translation	NN
cord-015935-r2wd1yfa	87	2	is	be	VBZ
cord-015935-r2wd1yfa	87	3	the	the	DT
cord-015935-r2wd1yfa	87	4	production	production	NN
cord-015935-r2wd1yfa	87	5	of	of	IN
cord-015935-r2wd1yfa	87	6	proteins	protein	NNS
cord-015935-r2wd1yfa	87	7	by	by	IN
cord-015935-r2wd1yfa	87	8	decoding	decode	VBG
cord-015935-r2wd1yfa	87	9	the	the	DT
cord-015935-r2wd1yfa	87	10	mRNA	mrna	NN
cord-015935-r2wd1yfa	87	11	that	that	WDT
cord-015935-r2wd1yfa	87	12	was	be	VBD
cord-015935-r2wd1yfa	87	13	produced	produce	VBN
cord-015935-r2wd1yfa	87	14	by	by	IN
cord-015935-r2wd1yfa	87	15	transcription	transcription	NN
cord-015935-r2wd1yfa	87	16	and	and	CC
cord-015935-r2wd1yfa	87	17	splicing	splicing	NN
cord-015935-r2wd1yfa	87	18	.	.	.
cord-015935-r2wd1yfa	88	1	The	the	DT
cord-015935-r2wd1yfa	88	2	mRNA	mrna	NN
cord-015935-r2wd1yfa	88	3	sequence	sequence	NN
cord-015935-r2wd1yfa	88	4	is	be	VBZ
cord-015935-r2wd1yfa	88	5	the	the	DT
cord-015935-r2wd1yfa	88	6	template	template	NN
cord-015935-r2wd1yfa	88	7	that	that	WDT
cord-015935-r2wd1yfa	88	8	guides	guide	VBZ
cord-015935-r2wd1yfa	88	9	the	the	DT
cord-015935-r2wd1yfa	88	10	production	production	NN
cord-015935-r2wd1yfa	88	11	of	of	IN
cord-015935-r2wd1yfa	88	12	a	a	DT
cord-015935-r2wd1yfa	88	13	chain	chain	NN
cord-015935-r2wd1yfa	88	14	of	of	IN
cord-015935-r2wd1yfa	88	15	amino	amino	JJ
cord-015935-r2wd1yfa	88	16	acids	acid	NNS
cord-015935-r2wd1yfa	88	17	that	that	WDT
cord-015935-r2wd1yfa	88	18	form	form	VBP
cord-015935-r2wd1yfa	88	19	a	a	DT
cord-015935-r2wd1yfa	88	20	protein	protein	NN
cord-015935-r2wd1yfa	88	21	.	.	.
cord-015935-r2wd1yfa	89	1	decade	decade	NN
cord-015935-r2wd1yfa	89	2	,	,	,
cord-015935-r2wd1yfa	89	3	this	this	DT
cord-015935-r2wd1yfa	89	4	technique	technique	NN
cord-015935-r2wd1yfa	89	5	enables	enable	VBZ
cord-015935-r2wd1yfa	89	6	examination	examination	NN
cord-015935-r2wd1yfa	89	7	of	of	IN
cord-015935-r2wd1yfa	89	8	the	the	DT
cord-015935-r2wd1yfa	89	9	whole	whole	JJ
cord-015935-r2wd1yfa	89	10	human	human	JJ
cord-015935-r2wd1yfa	89	11	genome	genome	NN
cord-015935-r2wd1yfa	89	12	on	on	IN
cord-015935-r2wd1yfa	89	13	a	a	DT
cord-015935-r2wd1yfa	89	14	single	single	JJ
cord-015935-r2wd1yfa	89	15	chip	chip	NN
cord-015935-r2wd1yfa	89	16	with	with	IN
cord-015935-r2wd1yfa	89	17	a	a	DT
cord-015935-r2wd1yfa	89	18	resolution	resolution	NN
cord-015935-r2wd1yfa	89	19	as	as	RB
cord-015935-r2wd1yfa	89	20	high	high	JJ
cord-015935-r2wd1yfa	89	21	as	as	IN
cord-015935-r2wd1yfa	89	22	a	a	DT
cord-015935-r2wd1yfa	89	23	few	few	JJ
cord-015935-r2wd1yfa	89	24	hundred	hundred	CD
cord-015935-r2wd1yfa	89	25	base	base	NN
cord-015935-r2wd1yfa	89	26	pairs	pair	NNS
cord-015935-r2wd1yfa	89	27	.	.	.
cord-015935-r2wd1yfa	90	1	This	this	DT
cord-015935-r2wd1yfa	90	2	resolution	resolution	NN
cord-015935-r2wd1yfa	90	3	is	be	VBZ
cord-015935-r2wd1yfa	90	4	at	at	IN
cord-015935-r2wd1yfa	90	5	least	least	JJS
cord-015935-r2wd1yfa	90	6	10-fold	10-fold	CD
cord-015935-r2wd1yfa	90	7	greater	great	JJR
cord-015935-r2wd1yfa	90	8	than	than	IN
cord-015935-r2wd1yfa	90	9	the	the	DT
cord-015935-r2wd1yfa	90	10	best	good	JJS
cord-015935-r2wd1yfa	90	11	prometaphase	prometaphase	NN
cord-015935-r2wd1yfa	90	12	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	90	13	analysis	analysis	NN
cord-015935-r2wd1yfa	90	14	and	and	CC
cord-015935-r2wd1yfa	90	15	therefore	therefore	RB
cord-015935-r2wd1yfa	90	16	,	,	,
cord-015935-r2wd1yfa	90	17	it	-PRON-	PRP
cord-015935-r2wd1yfa	90	18	is	be	VBZ
cord-015935-r2wd1yfa	90	19	the	the	DT
cord-015935-r2wd1yfa	90	20	most	most	RBS
cord-015935-r2wd1yfa	90	21	sensitive	sensitive	JJ
cord-015935-r2wd1yfa	90	22	for	for	IN
cord-015935-r2wd1yfa	90	23	whole	whole	JJ
cord-015935-r2wd1yfa	90	24	genome	genome	NN
cord-015935-r2wd1yfa	90	25	screen	screen	NN
cord-015935-r2wd1yfa	90	26	for	for	IN
cord-015935-r2wd1yfa	90	27	deletions	deletion	NNS
cord-015935-r2wd1yfa	90	28	and	and	CC
cord-015935-r2wd1yfa	90	29	duplications	duplication	NNS
cord-015935-r2wd1yfa	90	30	.	.	.
cord-015935-r2wd1yfa	91	1	Penetrance	Penetrance	NNP
cord-015935-r2wd1yfa	91	2	.	.	.
cord-015935-r2wd1yfa	92	1	The	the	DT
cord-015935-r2wd1yfa	92	2	proportion	proportion	NN
cord-015935-r2wd1yfa	92	3	of	of	IN
cord-015935-r2wd1yfa	92	4	individuals	individual	NNS
cord-015935-r2wd1yfa	92	5	carrying	carry	VBG
cord-015935-r2wd1yfa	92	6	a	a	DT
cord-015935-r2wd1yfa	92	7	particular	particular	JJ
cord-015935-r2wd1yfa	92	8	variation	variation	NN
cord-015935-r2wd1yfa	92	9	of	of	IN
cord-015935-r2wd1yfa	92	10	a	a	DT
cord-015935-r2wd1yfa	92	11	gene	gene	NN
cord-015935-r2wd1yfa	92	12	that	that	WDT
cord-015935-r2wd1yfa	92	13	also	also	RB
cord-015935-r2wd1yfa	92	14	expresses	express	VBZ
cord-015935-r2wd1yfa	92	15	an	an	DT
cord-015935-r2wd1yfa	92	16	associated	associate	VBN
cord-015935-r2wd1yfa	92	17	trait	trait	NN
cord-015935-r2wd1yfa	92	18	.	.	.
cord-015935-r2wd1yfa	93	1	For	for	IN
cord-015935-r2wd1yfa	93	2	example	example	NN
cord-015935-r2wd1yfa	93	3	,	,	,
cord-015935-r2wd1yfa	93	4	if	if	IN
cord-015935-r2wd1yfa	93	5	a	a	DT
cord-015935-r2wd1yfa	93	6	mutation	mutation	NN
cord-015935-r2wd1yfa	93	7	has	have	VBZ
cord-015935-r2wd1yfa	93	8	95	95	CD
cord-015935-r2wd1yfa	93	9	%	%	NN
cord-015935-r2wd1yfa	93	10	penetrance	penetrance	NN
cord-015935-r2wd1yfa	93	11	,	,	,
cord-015935-r2wd1yfa	93	12	then	then	RB
cord-015935-r2wd1yfa	93	13	95	95	CD
cord-015935-r2wd1yfa	93	14	%	%	NN
cord-015935-r2wd1yfa	93	15	of	of	IN
cord-015935-r2wd1yfa	93	16	those	those	DT
cord-015935-r2wd1yfa	93	17	with	with	IN
cord-015935-r2wd1yfa	93	18	the	the	DT
cord-015935-r2wd1yfa	93	19	mutation	mutation	NN
cord-015935-r2wd1yfa	93	20	will	will	MD
cord-015935-r2wd1yfa	93	21	develop	develop	VB
cord-015935-r2wd1yfa	93	22	the	the	DT
cord-015935-r2wd1yfa	93	23	syndrome	syndrome	NN
cord-015935-r2wd1yfa	93	24	,	,	,
cord-015935-r2wd1yfa	93	25	while	while	IN
cord-015935-r2wd1yfa	93	26	5	5	CD
cord-015935-r2wd1yfa	93	27	%	%	NN
cord-015935-r2wd1yfa	93	28	will	will	MD
cord-015935-r2wd1yfa	93	29	not	not	RB
cord-015935-r2wd1yfa	93	30	.	.	.
cord-015935-r2wd1yfa	94	1	is	be	VBZ
cord-015935-r2wd1yfa	94	2	expressed	express	VBN
cord-015935-r2wd1yfa	94	3	along	along	IN
cord-015935-r2wd1yfa	94	4	a	a	DT
cord-015935-r2wd1yfa	94	5	continuous	continuous	JJ
cord-015935-r2wd1yfa	94	6	phenotype	phenotype	NN
cord-015935-r2wd1yfa	94	7	,	,	,
cord-015935-r2wd1yfa	94	8	whose	whose	WP$
cord-015935-r2wd1yfa	94	9	extreme	extreme	JJ
cord-015935-r2wd1yfa	94	10	end	end	NN
cord-015935-r2wd1yfa	94	11	may	may	MD
cord-015935-r2wd1yfa	94	12	produce	produce	VB
cord-015935-r2wd1yfa	94	13	the	the	DT
cord-015935-r2wd1yfa	94	14	disorder	disorder	NN
cord-015935-r2wd1yfa	94	15	such	such	JJ
cord-015935-r2wd1yfa	94	16	as	as	IN
cord-015935-r2wd1yfa	94	17	hypertension	hypertension	NN
cord-015935-r2wd1yfa	94	18	,	,	,
cord-015935-r2wd1yfa	94	19	reading	read	VBG
cord-015935-r2wd1yfa	94	20	disability	disability	NN
cord-015935-r2wd1yfa	94	21	,	,	,
cord-015935-r2wd1yfa	94	22	or	or	CC
cord-015935-r2wd1yfa	94	23	attention	attention	NN
cord-015935-r2wd1yfa	94	24	-	-	HYPH
cord-015935-r2wd1yfa	94	25	deficit	deficit	NN
cord-015935-r2wd1yfa	94	26	disorder	disorder	NN
cord-015935-r2wd1yfa	94	27	with	with	IN
cord-015935-r2wd1yfa	94	28	hyperactivity	hyperactivity	NN
cord-015935-r2wd1yfa	94	29	(	(	-LRB-
cord-015935-r2wd1yfa	94	30	ADHD	ADHD	NNP
cord-015935-r2wd1yfa	94	31	)	)	-RRB-
cord-015935-r2wd1yfa	94	32	.	.	.
cord-015935-r2wd1yfa	95	1	Recessive	recessive	JJ
cord-015935-r2wd1yfa	95	2	genetic	genetic	JJ
cord-015935-r2wd1yfa	95	3	disorders	disorder	NNS
cord-015935-r2wd1yfa	95	4	.	.	.
cord-015935-r2wd1yfa	96	1	A	a	DT
cord-015935-r2wd1yfa	96	2	number	number	NN
cord-015935-r2wd1yfa	96	3	of	of	IN
cord-015935-r2wd1yfa	96	4	genetic	genetic	JJ
cord-015935-r2wd1yfa	96	5	disorders	disorder	NNS
cord-015935-r2wd1yfa	96	6	are	be	VBP
cord-015935-r2wd1yfa	96	7	caused	cause	VBN
cord-015935-r2wd1yfa	96	8	when	when	WRB
cord-015935-r2wd1yfa	96	9	an	an	DT
cord-015935-r2wd1yfa	96	10	individual	individual	NN
cord-015935-r2wd1yfa	96	11	inherits	inherit	VBZ
cord-015935-r2wd1yfa	96	12	two	two	CD
cord-015935-r2wd1yfa	96	13	recessive	recessive	JJ
cord-015935-r2wd1yfa	96	14	alleles	allele	NNS
cord-015935-r2wd1yfa	96	15	for	for	IN
cord-015935-r2wd1yfa	96	16	a	a	DT
cord-015935-r2wd1yfa	96	17	single	single	JJ
cord-015935-r2wd1yfa	96	18	gene	gene	NN
cord-015935-r2wd1yfa	96	19	trait	trait	NN
cord-015935-r2wd1yfa	96	20	,	,	,
cord-015935-r2wd1yfa	96	21	such	such	JJ
cord-015935-r2wd1yfa	96	22	as	as	IN
cord-015935-r2wd1yfa	96	23	with	with	IN
cord-015935-r2wd1yfa	96	24	cystic	cystic	JJ
cord-015935-r2wd1yfa	96	25	fibrosis	fibrosis	NN
cord-015935-r2wd1yfa	96	26	,	,	,
cord-015935-r2wd1yfa	96	27	PKU	PKU	NNP
cord-015935-r2wd1yfa	96	28	,	,	,
cord-015935-r2wd1yfa	96	29	or	or	CC
cord-015935-r2wd1yfa	96	30	albinism	albinism	NN
cord-015935-r2wd1yfa	96	31	.	.	.
cord-015935-r2wd1yfa	97	1	Recessive	recessive	JJ
cord-015935-r2wd1yfa	97	2	alleles	allele	NNS
cord-015935-r2wd1yfa	97	3	can	can	MD
cord-015935-r2wd1yfa	97	4	be	be	VB
cord-015935-r2wd1yfa	97	5	located	locate	VBN
cord-015935-r2wd1yfa	97	6	on	on	IN
cord-015935-r2wd1yfa	97	7	the	the	DT
cord-015935-r2wd1yfa	97	8	X	x	NN
cord-015935-r2wd1yfa	97	9	chromosome	chromosome	NN
cord-015935-r2wd1yfa	97	10	so	so	IN
cord-015935-r2wd1yfa	97	11	that	that	IN
cord-015935-r2wd1yfa	97	12	males	male	NNS
cord-015935-r2wd1yfa	97	13	are	be	VBP
cord-015935-r2wd1yfa	97	14	more	more	RBR
cord-015935-r2wd1yfa	97	15	affected	affected	JJ
cord-015935-r2wd1yfa	97	16	than	than	IN
cord-015935-r2wd1yfa	97	17	females	female	NNS
cord-015935-r2wd1yfa	97	18	(	(	-LRB-
cord-015935-r2wd1yfa	97	19	hemizygous	hemizygous	NNP
cord-015935-r2wd1yfa	97	20	)	)	-RRB-
cord-015935-r2wd1yfa	97	21	,	,	,
cord-015935-r2wd1yfa	97	22	such	such	JJ
cord-015935-r2wd1yfa	97	23	as	as	IN
cord-015935-r2wd1yfa	97	24	in	in	IN
cord-015935-r2wd1yfa	97	25	fragile	fragile	JJ
cord-015935-r2wd1yfa	97	26	X.	X.	NNP
cord-015935-r2wd1yfa	97	27	A	a	DT
cord-015935-r2wd1yfa	97	28	microarray	microarray	NN
cord-015935-r2wd1yfa	97	29	technique	technique	NN
cord-015935-r2wd1yfa	97	30	that	that	WDT
cord-015935-r2wd1yfa	97	31	identifies	identify	VBZ
cord-015935-r2wd1yfa	97	32	a	a	DT
cord-015935-r2wd1yfa	97	33	single	single	JJ
cord-015935-r2wd1yfa	97	34	point	point	NN
cord-015935-r2wd1yfa	97	35	mutation	mutation	NN
cord-015935-r2wd1yfa	97	36	via	via	IN
cord-015935-r2wd1yfa	97	37	sequencing	sequence	VBG
cord-015935-r2wd1yfa	97	38	the	the	DT
cord-015935-r2wd1yfa	97	39	gene	gene	NN
cord-015935-r2wd1yfa	97	40	in	in	IN
cord-015935-r2wd1yfa	97	41	areas	area	NNS
cord-015935-r2wd1yfa	97	42	of	of	IN
cord-015935-r2wd1yfa	97	43	suspected	suspect	VBN
cord-015935-r2wd1yfa	97	44	abnormality	abnormality	NN
cord-015935-r2wd1yfa	97	45	as	as	IN
cord-015935-r2wd1yfa	97	46	identified	identify	VBN
cord-015935-r2wd1yfa	97	47	via	via	IN
cord-015935-r2wd1yfa	97	48	CGH	CGH	NNP
cord-015935-r2wd1yfa	97	49	or	or	CC
cord-015935-r2wd1yfa	97	50	FISH	fish	NN
cord-015935-r2wd1yfa	97	51	.	.	.
cord-015935-r2wd1yfa	98	1	This	this	DT
cord-015935-r2wd1yfa	98	2	looks	look	VBZ
cord-015935-r2wd1yfa	98	3	at	at	IN
cord-015935-r2wd1yfa	98	4	a	a	DT
cord-015935-r2wd1yfa	98	5	smaller	small	JJR
cord-015935-r2wd1yfa	98	6	region	region	NN
cord-015935-r2wd1yfa	98	7	with	with	IN
cord-015935-r2wd1yfa	98	8	greater	great	JJR
cord-015935-r2wd1yfa	98	9	detail	detail	NN
cord-015935-r2wd1yfa	98	10	than	than	IN
cord-015935-r2wd1yfa	98	11	does	do	VBZ
cord-015935-r2wd1yfa	98	12	CGH	CGH	NNP
cord-015935-r2wd1yfa	98	13	.	.	.
cord-015935-r2wd1yfa	99	1	*	*	NFP
cord-015935-r2wd1yfa	100	1	*	*	NFP
cord-015935-r2wd1yfa	100	2	Solomon	Solomon	NNP
cord-015935-r2wd1yfa	100	3	,	,	,
cord-015935-r2wd1yfa	100	4	Berg	Berg	NNP
cord-015935-r2wd1yfa	100	5	,	,	,
cord-015935-r2wd1yfa	100	6	and	and	CC
cord-015935-r2wd1yfa	100	7	Martin	Martin	NNP
cord-015935-r2wd1yfa	100	8	(	(	-LRB-
cord-015935-r2wd1yfa	100	9	2008	2008	CD
cord-015935-r2wd1yfa	100	10	)	)	-RRB-
cord-015935-r2wd1yfa	100	11	 	 	_SP
cord-015935-r2wd1yfa	101	1	During	during	IN
cord-015935-r2wd1yfa	101	2	embryologic	embryologic	JJ
cord-015935-r2wd1yfa	101	3	development	development	NN
cord-015935-r2wd1yfa	101	4	,	,	,
cord-015935-r2wd1yfa	101	5	the	the	DT
cord-015935-r2wd1yfa	101	6	brain	brain	NN
cord-015935-r2wd1yfa	101	7	emerges	emerge	VBZ
cord-015935-r2wd1yfa	101	8	from	from	IN
cord-015935-r2wd1yfa	101	9	the	the	DT
cord-015935-r2wd1yfa	101	10	neural	neural	JJ
cord-015935-r2wd1yfa	101	11	tube	tube	NN
cord-015935-r2wd1yfa	101	12	,	,	,
cord-015935-r2wd1yfa	101	13	an	an	DT
cord-015935-r2wd1yfa	101	14	early	early	JJ
cord-015935-r2wd1yfa	101	15	embryonic	embryonic	JJ
cord-015935-r2wd1yfa	101	16	structure	structure	NN
cord-015935-r2wd1yfa	101	17	.	.	.
cord-015935-r2wd1yfa	102	1	The	the	DT
cord-015935-r2wd1yfa	102	2	anterior	anterior	JJ
cord-015935-r2wd1yfa	102	3	neural	neural	JJ
cord-015935-r2wd1yfa	102	4	tube	tube	NN
cord-015935-r2wd1yfa	102	5	expands	expand	VBZ
cord-015935-r2wd1yfa	102	6	rapidly	rapidly	RB
cord-015935-r2wd1yfa	102	7	due	due	JJ
cord-015935-r2wd1yfa	102	8	to	to	IN
cord-015935-r2wd1yfa	102	9	cell	cell	NN
cord-015935-r2wd1yfa	102	10	proliferation	proliferation	NN
cord-015935-r2wd1yfa	102	11	and	and	CC
cord-015935-r2wd1yfa	102	12	eventually	eventually	RB
cord-015935-r2wd1yfa	102	13	gives	give	VBZ
cord-015935-r2wd1yfa	102	14	rise	rise	NN
cord-015935-r2wd1yfa	102	15	to	to	IN
cord-015935-r2wd1yfa	102	16	the	the	DT
cord-015935-r2wd1yfa	102	17	brain	brain	NN
cord-015935-r2wd1yfa	102	18	.	.	.
cord-015935-r2wd1yfa	103	1	Cells	cell	NNS
cord-015935-r2wd1yfa	103	2	stop	stop	VBP
cord-015935-r2wd1yfa	103	3	dividing	divide	VBG
cord-015935-r2wd1yfa	103	4	and	and	CC
cord-015935-r2wd1yfa	103	5	differentiate	differentiate	VB
cord-015935-r2wd1yfa	103	6	into	into	IN
cord-015935-r2wd1yfa	103	7	neurons	neuron	NNS
cord-015935-r2wd1yfa	103	8	and	and	CC
cord-015935-r2wd1yfa	103	9	glial	glial	JJ
cord-015935-r2wd1yfa	103	10	cells	cell	NNS
cord-015935-r2wd1yfa	103	11	,	,	,
cord-015935-r2wd1yfa	103	12	the	the	DT
cord-015935-r2wd1yfa	103	13	main	main	JJ
cord-015935-r2wd1yfa	103	14	cellular	cellular	JJ
cord-015935-r2wd1yfa	103	15	components	component	NNS
cord-015935-r2wd1yfa	103	16	of	of	IN
cord-015935-r2wd1yfa	103	17	the	the	DT
cord-015935-r2wd1yfa	103	18	brain	brain	NN
cord-015935-r2wd1yfa	103	19	.	.	.
cord-015935-r2wd1yfa	104	1	The	the	DT
cord-015935-r2wd1yfa	104	2	neurons	neuron	NNS
cord-015935-r2wd1yfa	104	3	must	must	MD
cord-015935-r2wd1yfa	104	4	migrate	migrate	VB
cord-015935-r2wd1yfa	104	5	to	to	IN
cord-015935-r2wd1yfa	104	6	different	different	JJ
cord-015935-r2wd1yfa	104	7	parts	part	NNS
cord-015935-r2wd1yfa	104	8	of	of	IN
cord-015935-r2wd1yfa	104	9	the	the	DT
cord-015935-r2wd1yfa	104	10	developing	develop	VBG
cord-015935-r2wd1yfa	104	11	brain	brain	NN
cord-015935-r2wd1yfa	104	12	to	to	IN
cord-015935-r2wd1yfa	104	13	self	self	NN
cord-015935-r2wd1yfa	104	14	-	-	HYPH
cord-015935-r2wd1yfa	104	15	organize	organize	VB
cord-015935-r2wd1yfa	104	16	into	into	IN
cord-015935-r2wd1yfa	104	17	different	different	JJ
cord-015935-r2wd1yfa	104	18	brain	brain	NN
cord-015935-r2wd1yfa	104	19	structures	structure	NNS
cord-015935-r2wd1yfa	104	20	.	.	.
cord-015935-r2wd1yfa	105	1	The	the	DT
cord-015935-r2wd1yfa	105	2	neurons	neuron	NNS
cord-015935-r2wd1yfa	105	3	grow	grow	VBP
cord-015935-r2wd1yfa	105	4	connections	connection	NNS
cord-015935-r2wd1yfa	105	5	(	(	-LRB-
cord-015935-r2wd1yfa	105	6	axons	axon	NNS
cord-015935-r2wd1yfa	105	7	and	and	CC
cord-015935-r2wd1yfa	105	8	dendrites	dendrite	NNS
cord-015935-r2wd1yfa	105	9	)	)	-RRB-
cord-015935-r2wd1yfa	105	10	which	which	WDT
cord-015935-r2wd1yfa	105	11	often	often	RB
cord-015935-r2wd1yfa	105	12	must	must	MD
cord-015935-r2wd1yfa	105	13	span	span	VB
cord-015935-r2wd1yfa	105	14	long	long	JJ
cord-015935-r2wd1yfa	105	15	distances	distance	NNS
cord-015935-r2wd1yfa	105	16	to	to	TO
cord-015935-r2wd1yfa	105	17	reach	reach	VB
cord-015935-r2wd1yfa	105	18	their	-PRON-	PRP$
cord-015935-r2wd1yfa	105	19	target	target	NN
cord-015935-r2wd1yfa	105	20	cells	cell	NNS
cord-015935-r2wd1yfa	105	21	.	.	.
cord-015935-r2wd1yfa	106	1	Growth	growth	NN
cord-015935-r2wd1yfa	106	2	cones	cone	NNS
cord-015935-r2wd1yfa	106	3	are	be	VBP
cord-015935-r2wd1yfa	106	4	the	the	DT
cord-015935-r2wd1yfa	106	5	highly	highly	RB
cord-015935-r2wd1yfa	106	6	motile	motile	JJ
cord-015935-r2wd1yfa	106	7	filamentous	filamentous	JJ
cord-015935-r2wd1yfa	106	8	connections	connection	NNS
cord-015935-r2wd1yfa	106	9	that	that	WDT
cord-015935-r2wd1yfa	106	10	eventually	eventually	RB
cord-015935-r2wd1yfa	106	11	form	form	VBP
cord-015935-r2wd1yfa	106	12	more	more	RBR
cord-015935-r2wd1yfa	106	13	stable	stable	JJ
cord-015935-r2wd1yfa	106	14	synapses	synapsis	NNS
cord-015935-r2wd1yfa	106	15	between	between	IN
cord-015935-r2wd1yfa	106	16	neurons	neuron	NNS
cord-015935-r2wd1yfa	106	17	.	.	.
cord-015935-r2wd1yfa	107	1	Neurons	neuron	NNS
cord-015935-r2wd1yfa	107	2	communicate	communicate	VBP
cord-015935-r2wd1yfa	107	3	with	with	IN
cord-015935-r2wd1yfa	107	4	other	other	JJ
cord-015935-r2wd1yfa	107	5	neurons	neuron	NNS
cord-015935-r2wd1yfa	107	6	via	via	IN
cord-015935-r2wd1yfa	107	7	these	these	DT
cord-015935-r2wd1yfa	107	8	synapses	synapsis	NNS
cord-015935-r2wd1yfa	107	9	.	.	.
cord-015935-r2wd1yfa	108	1	This	this	DT
cord-015935-r2wd1yfa	108	2	communication	communication	NN
cord-015935-r2wd1yfa	108	3	leads	lead	VBZ
cord-015935-r2wd1yfa	108	4	to	to	IN
cord-015935-r2wd1yfa	108	5	the	the	DT
cord-015935-r2wd1yfa	108	6	establishment	establishment	NN
cord-015935-r2wd1yfa	108	7	of	of	IN
cord-015935-r2wd1yfa	108	8	functional	functional	JJ
cord-015935-r2wd1yfa	108	9	neural	neural	JJ
cord-015935-r2wd1yfa	108	10	circuits	circuit	NNS
cord-015935-r2wd1yfa	108	11	that	that	WDT
cord-015935-r2wd1yfa	108	12	mediate	mediate	VBP
cord-015935-r2wd1yfa	108	13	sensory	sensory	JJ
cord-015935-r2wd1yfa	108	14	-	-	HYPH
cord-015935-r2wd1yfa	108	15	motor	motor	NN
cord-015935-r2wd1yfa	108	16	processing	processing	NN
cord-015935-r2wd1yfa	108	17	and	and	CC
cord-015935-r2wd1yfa	108	18	behavior	behavior	NN
cord-015935-r2wd1yfa	108	19	.	.	.
cord-015935-r2wd1yfa	109	1	Associated	associate	VBN
cord-015935-r2wd1yfa	109	2	with	with	IN
cord-015935-r2wd1yfa	109	3	this	this	DT
cord-015935-r2wd1yfa	109	4	period	period	NN
cord-015935-r2wd1yfa	109	5	of	of	IN
cord-015935-r2wd1yfa	109	6	synaptogenesis	synaptogenesis	NN
cord-015935-r2wd1yfa	109	7	is	be	VBZ
cord-015935-r2wd1yfa	109	8	a	a	DT
cord-015935-r2wd1yfa	109	9	brief	brief	JJ
cord-015935-r2wd1yfa	109	10	period	period	NN
cord-015935-r2wd1yfa	109	11	of	of	IN
cord-015935-r2wd1yfa	109	12	"	"	``
cord-015935-r2wd1yfa	109	13	programmed	program	VBN
cord-015935-r2wd1yfa	109	14	"	"	''
cord-015935-r2wd1yfa	109	15	cell	cell	NN
cord-015935-r2wd1yfa	109	16	death	death	NN
cord-015935-r2wd1yfa	109	17	,	,	,
cord-015935-r2wd1yfa	109	18	a	a	DT
cord-015935-r2wd1yfa	109	19	pruning	pruning	NN
cord-015935-r2wd1yfa	109	20	process	process	NN
cord-015935-r2wd1yfa	109	21	in	in	IN
cord-015935-r2wd1yfa	109	22	which	which	WDT
cord-015935-r2wd1yfa	109	23	cells	cell	NNS
cord-015935-r2wd1yfa	109	24	succumb	succumb	VBP
cord-015935-r2wd1yfa	109	25	during	during	IN
cord-015935-r2wd1yfa	109	26	natural	natural	JJ
cord-015935-r2wd1yfa	109	27	development	development	NN
cord-015935-r2wd1yfa	109	28	(	(	-LRB-
cord-015935-r2wd1yfa	109	29	Mattson	Mattson	NNP
cord-015935-r2wd1yfa	109	30	&	&	CC
cord-015935-r2wd1yfa	109	31	Furukawa	Furukawa	NNP
cord-015935-r2wd1yfa	109	32	,	,	,
cord-015935-r2wd1yfa	109	33	1998	1998	CD
cord-015935-r2wd1yfa	109	34	)	)	-RRB-
cord-015935-r2wd1yfa	109	35	.	.	.
cord-015935-r2wd1yfa	110	1	Migration	migration	NN
cord-015935-r2wd1yfa	110	2	of	of	IN
cord-015935-r2wd1yfa	110	3	cells	cell	NNS
cord-015935-r2wd1yfa	110	4	from	from	IN
cord-015935-r2wd1yfa	110	5	the	the	DT
cord-015935-r2wd1yfa	110	6	ventricular	ventricular	JJ
cord-015935-r2wd1yfa	110	7	zone	zone	NN
cord-015935-r2wd1yfa	110	8	lining	line	VBG
cord-015935-r2wd1yfa	110	9	the	the	DT
cord-015935-r2wd1yfa	110	10	central	central	JJ
cord-015935-r2wd1yfa	110	11	canal	canal	NN
cord-015935-r2wd1yfa	110	12	of	of	IN
cord-015935-r2wd1yfa	110	13	the	the	DT
cord-015935-r2wd1yfa	110	14	neural	neural	JJ
cord-015935-r2wd1yfa	110	15	tube	tube	NN
cord-015935-r2wd1yfa	110	16	to	to	IN
cord-015935-r2wd1yfa	110	17	the	the	DT
cord-015935-r2wd1yfa	110	18	developing	develop	VBG
cord-015935-r2wd1yfa	110	19	cortex	cortex	NN
cord-015935-r2wd1yfa	110	20	next	next	JJ
cord-015935-r2wd1yfa	110	21	takes	take	VBZ
cord-015935-r2wd1yfa	110	22	place	place	NN
cord-015935-r2wd1yfa	110	23	followed	follow	VBN
cord-015935-r2wd1yfa	110	24	by	by	IN
cord-015935-r2wd1yfa	110	25	a	a	DT
cord-015935-r2wd1yfa	110	26	more	more	RBR
cord-015935-r2wd1yfa	110	27	protracted	protracted	JJ
cord-015935-r2wd1yfa	110	28	period	period	NN
cord-015935-r2wd1yfa	110	29	of	of	IN
cord-015935-r2wd1yfa	110	30	pruning	pruning	NN
cord-015935-r2wd1yfa	110	31	(	(	-LRB-
cord-015935-r2wd1yfa	110	32	Volpe	Volpe	NNP
cord-015935-r2wd1yfa	110	33	,	,	,
cord-015935-r2wd1yfa	110	34	2001	2001	CD
cord-015935-r2wd1yfa	110	35	)	)	-RRB-
cord-015935-r2wd1yfa	110	36	.	.	.
cord-015935-r2wd1yfa	111	1	One	one	CD
cord-015935-r2wd1yfa	111	2	mechanism	mechanism	NN
cord-015935-r2wd1yfa	111	3	that	that	WDT
cord-015935-r2wd1yfa	111	4	allows	allow	VBZ
cord-015935-r2wd1yfa	111	5	cells	cell	NNS
cord-015935-r2wd1yfa	111	6	to	to	TO
cord-015935-r2wd1yfa	111	7	detach	detach	VB
cord-015935-r2wd1yfa	111	8	and	and	CC
cord-015935-r2wd1yfa	111	9	migrate	migrate	VB
cord-015935-r2wd1yfa	111	10	away	away	RB
cord-015935-r2wd1yfa	111	11	from	from	IN
cord-015935-r2wd1yfa	111	12	each	each	DT
cord-015935-r2wd1yfa	111	13	other	other	JJ
cord-015935-r2wd1yfa	111	14	appears	appear	VBZ
cord-015935-r2wd1yfa	111	15	to	to	TO
cord-015935-r2wd1yfa	111	16	be	be	VB
cord-015935-r2wd1yfa	111	17	regulated	regulate	VBN
cord-015935-r2wd1yfa	111	18	by	by	IN
cord-015935-r2wd1yfa	111	19	a	a	DT
cord-015935-r2wd1yfa	111	20	"	"	``
cord-015935-r2wd1yfa	111	21	molecular	molecular	JJ
cord-015935-r2wd1yfa	111	22	switch	switch	NN
cord-015935-r2wd1yfa	111	23	"	"	''
cord-015935-r2wd1yfa	111	24	regulated	regulate	VBN
cord-015935-r2wd1yfa	111	25	by	by	IN
cord-015935-r2wd1yfa	111	26	catenin	catenin	NN
cord-015935-r2wd1yfa	111	27	adhesion	adhesion	NN
cord-015935-r2wd1yfa	111	28	proteins	protein	NNS
cord-015935-r2wd1yfa	111	29	(	(	-LRB-
cord-015935-r2wd1yfa	111	30	DiCicco	DiCicco	NNP
cord-015935-r2wd1yfa	111	31	-	-	HYPH
cord-015935-r2wd1yfa	111	32	Bloom	Bloom	NNP
cord-015935-r2wd1yfa	111	33	,	,	,
cord-015935-r2wd1yfa	111	34	2006	2006	CD
cord-015935-r2wd1yfa	111	35	)	)	-RRB-
cord-015935-r2wd1yfa	111	36	.	.	.
cord-015935-r2wd1yfa	112	1	Neuroligin	Neuroligin	NNP
cord-015935-r2wd1yfa	112	2	,	,	,
cord-015935-r2wd1yfa	112	3	recently	recently	RB
cord-015935-r2wd1yfa	112	4	described	describe	VBN
cord-015935-r2wd1yfa	112	5	in	in	IN
cord-015935-r2wd1yfa	112	6	autism	autism	NN
cord-015935-r2wd1yfa	112	7	research	research	NN
cord-015935-r2wd1yfa	112	8	,	,	,
cord-015935-r2wd1yfa	112	9	is	be	VBZ
cord-015935-r2wd1yfa	112	10	a	a	DT
cord-015935-r2wd1yfa	112	11	cell	cell	NN
cord-015935-r2wd1yfa	112	12	adhesion	adhesion	NN
cord-015935-r2wd1yfa	112	13	molecule	molecule	NN
cord-015935-r2wd1yfa	112	14	found	find	VBN
cord-015935-r2wd1yfa	112	15	in	in	IN
cord-015935-r2wd1yfa	112	16	the	the	DT
cord-015935-r2wd1yfa	112	17	postsynaptic	postsynaptic	JJ
cord-015935-r2wd1yfa	112	18	membrane	membrane	NN
cord-015935-r2wd1yfa	112	19	.	.	.
cord-015935-r2wd1yfa	113	1	Also	also	RB
cord-015935-r2wd1yfa	113	2	,	,	,
cord-015935-r2wd1yfa	113	3	brain	brain	NN
cord-015935-r2wd1yfa	113	4	-	-	HYPH
cord-015935-r2wd1yfa	113	5	derived	derive	VBN
cord-015935-r2wd1yfa	113	6	neurotrophic	neurotrophic	NN
cord-015935-r2wd1yfa	113	7	factor	factor	NN
cord-015935-r2wd1yfa	113	8	(	(	-LRB-
cord-015935-r2wd1yfa	113	9	BDNF	BDNF	NNP
cord-015935-r2wd1yfa	113	10	)	)	-RRB-
cord-015935-r2wd1yfa	113	11	is	be	VBZ
cord-015935-r2wd1yfa	113	12	produced	produce	VBN
cord-015935-r2wd1yfa	113	13	by	by	IN
cord-015935-r2wd1yfa	113	14	the	the	DT
cord-015935-r2wd1yfa	113	15	brain	brain	NN
cord-015935-r2wd1yfa	113	16	and	and	CC
cord-015935-r2wd1yfa	113	17	regulates	regulate	VBZ
cord-015935-r2wd1yfa	113	18	several	several	JJ
cord-015935-r2wd1yfa	113	19	functions	function	NNS
cord-015935-r2wd1yfa	113	20	within	within	IN
cord-015935-r2wd1yfa	113	21	the	the	DT
cord-015935-r2wd1yfa	113	22	developing	develop	VBG
cord-015935-r2wd1yfa	113	23	synapse	synapse	NN
cord-015935-r2wd1yfa	113	24	,	,	,
cord-015935-r2wd1yfa	113	25	including	include	VBG
cord-015935-r2wd1yfa	113	26	enhancement	enhancement	NN
cord-015935-r2wd1yfa	113	27	of	of	IN
cord-015935-r2wd1yfa	113	28	neurotransmitter	neurotransmitter	NN
cord-015935-r2wd1yfa	113	29	release	release	NN
cord-015935-r2wd1yfa	113	30	.	.	.
cord-015935-r2wd1yfa	114	1	Activity	activity	NN
cord-015935-r2wd1yfa	114	2	at	at	IN
cord-015935-r2wd1yfa	114	3	the	the	DT
cord-015935-r2wd1yfa	114	4	CNS	CNS	NNP
cord-015935-r2wd1yfa	114	5	synapses	synapsis	NNS
cord-015935-r2wd1yfa	114	6	occurs	occur	VBZ
cord-015935-r2wd1yfa	114	7	over	over	IN
cord-015935-r2wd1yfa	114	8	the	the	DT
cord-015935-r2wd1yfa	114	9	life	life	NN
cord-015935-r2wd1yfa	114	10	span	span	NN
cord-015935-r2wd1yfa	114	11	and	and	CC
cord-015935-r2wd1yfa	114	12	is	be	VBZ
cord-015935-r2wd1yfa	114	13	thought	think	VBN
cord-015935-r2wd1yfa	114	14	to	to	TO
cord-015935-r2wd1yfa	114	15	underlie	underlie	VB
cord-015935-r2wd1yfa	114	16	learning	learning	NN
cord-015935-r2wd1yfa	114	17	and	and	CC
cord-015935-r2wd1yfa	114	18	memory	memory	NN
cord-015935-r2wd1yfa	114	19	.	.	.
cord-015935-r2wd1yfa	115	1	The	the	DT
cord-015935-r2wd1yfa	115	2	excitatory	excitatory	JJ
cord-015935-r2wd1yfa	115	3	neurotransmitter	neurotransmitter	NN
cord-015935-r2wd1yfa	115	4	glutamate	glutamate	NN
cord-015935-r2wd1yfa	115	5	and	and	CC
cord-015935-r2wd1yfa	115	6	its	-PRON-	PRP$
cord-015935-r2wd1yfa	115	7	receptors	receptor	NNS
cord-015935-r2wd1yfa	115	8	,	,	,
cord-015935-r2wd1yfa	115	9	particularly	particularly	RB
cord-015935-r2wd1yfa	115	10	the	the	DT
cord-015935-r2wd1yfa	115	11	N	n	CD
cord-015935-r2wd1yfa	115	12	-	-	HYPH
cord-015935-r2wd1yfa	115	13	methyl	methyl	NN
cord-015935-r2wd1yfa	115	14	-	-	HYPH
cord-015935-r2wd1yfa	115	15	D	d	NN
cord-015935-r2wd1yfa	115	16	-	-	HYPH
cord-015935-r2wd1yfa	115	17	aspartate	aspartate	NN
cord-015935-r2wd1yfa	115	18	(	(	-LRB-
cord-015935-r2wd1yfa	115	19	NMDA	NMDA	NNP
cord-015935-r2wd1yfa	115	20	)	)	-RRB-
cord-015935-r2wd1yfa	115	21	receptor	receptor	NN
cord-015935-r2wd1yfa	115	22	,	,	,
cord-015935-r2wd1yfa	115	23	initiate	initiate	VB
cord-015935-r2wd1yfa	115	24	synaptogenesis	synaptogenesis	NN
cord-015935-r2wd1yfa	115	25	through	through	IN
cord-015935-r2wd1yfa	115	26	activation	activation	NN
cord-015935-r2wd1yfa	115	27	of	of	IN
cord-015935-r2wd1yfa	115	28	downstream	downstream	JJ
cord-015935-r2wd1yfa	115	29	products	product	NNS
cord-015935-r2wd1yfa	115	30	.	.	.
cord-015935-r2wd1yfa	116	1	At	at	IN
cord-015935-r2wd1yfa	116	2	the	the	DT
cord-015935-r2wd1yfa	116	3	CNS	CNS	NNP
cord-015935-r2wd1yfa	116	4	synapse	synapse	NN
cord-015935-r2wd1yfa	116	5	,	,	,
cord-015935-r2wd1yfa	116	6	a	a	DT
cord-015935-r2wd1yfa	116	7	nerve	nerve	NN
cord-015935-r2wd1yfa	116	8	terminal	terminal	NN
cord-015935-r2wd1yfa	116	9	is	be	VBZ
cord-015935-r2wd1yfa	116	10	separated	separate	VBN
cord-015935-r2wd1yfa	116	11	from	from	IN
cord-015935-r2wd1yfa	116	12	the	the	DT
cord-015935-r2wd1yfa	116	13	postsynaptic	postsynaptic	JJ
cord-015935-r2wd1yfa	116	14	membrane	membrane	NN
cord-015935-r2wd1yfa	116	15	by	by	IN
cord-015935-r2wd1yfa	116	16	a	a	DT
cord-015935-r2wd1yfa	116	17	cleft	cleft	NN
cord-015935-r2wd1yfa	116	18	containing	contain	VBG
cord-015935-r2wd1yfa	116	19	specialized	specialized	JJ
cord-015935-r2wd1yfa	116	20	extracellular	extracellular	JJ
cord-015935-r2wd1yfa	116	21	material	material	NN
cord-015935-r2wd1yfa	116	22	.	.	.
cord-015935-r2wd1yfa	117	1	Localized	localized	JJ
cord-015935-r2wd1yfa	117	2	vesicles	vesicle	NNS
cord-015935-r2wd1yfa	117	3	are	be	VBP
cord-015935-r2wd1yfa	117	4	at	at	IN
cord-015935-r2wd1yfa	117	5	the	the	DT
cord-015935-r2wd1yfa	117	6	active	active	JJ
cord-015935-r2wd1yfa	117	7	sites	site	NNS
cord-015935-r2wd1yfa	117	8	and	and	CC
cord-015935-r2wd1yfa	117	9	clustered	cluster	VBN
cord-015935-r2wd1yfa	117	10	receptors	receptor	NNS
cord-015935-r2wd1yfa	117	11	are	be	VBP
cord-015935-r2wd1yfa	117	12	at	at	IN
cord-015935-r2wd1yfa	117	13	the	the	DT
cord-015935-r2wd1yfa	117	14	postsynaptic	postsynaptic	JJ
cord-015935-r2wd1yfa	117	15	membrane	membrane	NN
cord-015935-r2wd1yfa	117	16	with	with	IN
cord-015935-r2wd1yfa	117	17	glial	glial	JJ
cord-015935-r2wd1yfa	117	18	cells	cell	NNS
cord-015935-r2wd1yfa	117	19	that	that	WDT
cord-015935-r2wd1yfa	117	20	encapsulate	encapsulate	VBP
cord-015935-r2wd1yfa	117	21	the	the	DT
cord-015935-r2wd1yfa	117	22	entire	entire	JJ
cord-015935-r2wd1yfa	117	23	synaptic	synaptic	JJ
cord-015935-r2wd1yfa	117	24	cleft	cleft	NN
cord-015935-r2wd1yfa	117	25	.	.	.
cord-015935-r2wd1yfa	118	1	There	there	EX
cord-015935-r2wd1yfa	118	2	is	be	VBZ
cord-015935-r2wd1yfa	118	3	differentiation	differentiation	NN
cord-015935-r2wd1yfa	118	4	of	of	IN
cord-015935-r2wd1yfa	118	5	the	the	DT
cord-015935-r2wd1yfa	118	6	pre	pre	JJ
cord-015935-r2wd1yfa	118	7	-	-	JJ
cord-015935-r2wd1yfa	118	8	and	and	CC
cord-015935-r2wd1yfa	118	9	postsynaptic	postsynaptic	JJ
cord-015935-r2wd1yfa	118	10	membrane	membrane	NN
cord-015935-r2wd1yfa	118	11	following	follow	VBG
cord-015935-r2wd1yfa	118	12	initial	initial	JJ
cord-015935-r2wd1yfa	118	13	contact	contact	NN
cord-015935-r2wd1yfa	118	14	between	between	IN
cord-015935-r2wd1yfa	118	15	two	two	CD
cord-015935-r2wd1yfa	118	16	cells	cell	NNS
cord-015935-r2wd1yfa	118	17	.	.	.
cord-015935-r2wd1yfa	119	1	This	this	DT
cord-015935-r2wd1yfa	119	2	includes	include	VBZ
cord-015935-r2wd1yfa	119	3	the	the	DT
cord-015935-r2wd1yfa	119	4	clustering	clustering	NN
cord-015935-r2wd1yfa	119	5	of	of	IN
cord-015935-r2wd1yfa	119	6	receptors	receptor	NNS
cord-015935-r2wd1yfa	119	7	,	,	,
cord-015935-r2wd1yfa	119	8	localized	localize	VBN
cord-015935-r2wd1yfa	119	9	upregulation	upregulation	NN
cord-015935-r2wd1yfa	119	10	of	of	IN
cord-015935-r2wd1yfa	119	11	protein	protein	NN
cord-015935-r2wd1yfa	119	12	synthesis	synthesis	NN
cord-015935-r2wd1yfa	119	13	at	at	IN
cord-015935-r2wd1yfa	119	14	the	the	DT
cord-015935-r2wd1yfa	119	15	active	active	JJ
cord-015935-r2wd1yfa	119	16	sites	site	NNS
cord-015935-r2wd1yfa	119	17	,	,	,
cord-015935-r2wd1yfa	119	18	and	and	CC
cord-015935-r2wd1yfa	119	19	continued	continue	VBN
cord-015935-r2wd1yfa	119	20	neuronal	neuronal	JJ
cord-015935-r2wd1yfa	119	21	pruning	pruning	NN
cord-015935-r2wd1yfa	119	22	through	through	IN
cord-015935-r2wd1yfa	119	23	synapse	synapse	NN
cord-015935-r2wd1yfa	119	24	elimination	elimination	NN
cord-015935-r2wd1yfa	119	25	.	.	.
cord-015935-r2wd1yfa	120	1	Neurons	neuron	NNS
cord-015935-r2wd1yfa	120	2	within	within	IN
cord-015935-r2wd1yfa	120	3	the	the	DT
cord-015935-r2wd1yfa	120	4	CNS	CNS	NNP
cord-015935-r2wd1yfa	120	5	receive	receive	VBP
cord-015935-r2wd1yfa	120	6	multiple	multiple	JJ
cord-015935-r2wd1yfa	120	7	inputs	input	NNS
cord-015935-r2wd1yfa	120	8	that	that	WDT
cord-015935-r2wd1yfa	120	9	must	must	MD
cord-015935-r2wd1yfa	120	10	be	be	VB
cord-015935-r2wd1yfa	120	11	processed	process	VBN
cord-015935-r2wd1yfa	120	12	and	and	CC
cord-015935-r2wd1yfa	120	13	integrated	integrate	VBN
cord-015935-r2wd1yfa	120	14	for	for	IN
cord-015935-r2wd1yfa	120	15	successful	successful	JJ
cord-015935-r2wd1yfa	120	16	transfer	transfer	NN
cord-015935-r2wd1yfa	120	17	of	of	IN
cord-015935-r2wd1yfa	120	18	information	information	NN
cord-015935-r2wd1yfa	120	19	.	.	.
cord-015935-r2wd1yfa	121	1	The	the	DT
cord-015935-r2wd1yfa	121	2	multiple	multiple	JJ
cord-015935-r2wd1yfa	121	3	inputs	input	NNS
cord-015935-r2wd1yfa	121	4	physically	physically	RB
cord-015935-r2wd1yfa	121	5	represent	represent	VBP
cord-015935-r2wd1yfa	121	6	the	the	DT
cord-015935-r2wd1yfa	121	7	plasticity	plasticity	NN
cord-015935-r2wd1yfa	121	8	of	of	IN
cord-015935-r2wd1yfa	121	9	the	the	DT
cord-015935-r2wd1yfa	121	10	brain	brain	NN
cord-015935-r2wd1yfa	121	11	.	.	.
cord-015935-r2wd1yfa	122	1	Macrocephaly	Macrocephaly	NNP
cord-015935-r2wd1yfa	122	2	has	have	VBZ
cord-015935-r2wd1yfa	122	3	been	be	VBN
cord-015935-r2wd1yfa	122	4	one	one	CD
cord-015935-r2wd1yfa	122	5	of	of	IN
cord-015935-r2wd1yfa	122	6	the	the	DT
cord-015935-r2wd1yfa	122	7	"	"	``
cord-015935-r2wd1yfa	122	8	most	most	RBS
cord-015935-r2wd1yfa	122	9	widely	widely	RB
cord-015935-r2wd1yfa	122	10	replicated	replicate	VBN
cord-015935-r2wd1yfa	122	11	biological	biological	JJ
cord-015935-r2wd1yfa	122	12	findings	finding	NNS
cord-015935-r2wd1yfa	122	13	in	in	IN
cord-015935-r2wd1yfa	122	14	autism	autism	NN
cord-015935-r2wd1yfa	122	15	"	"	''
cord-015935-r2wd1yfa	122	16	(	(	-LRB-
cord-015935-r2wd1yfa	122	17	McCaffery	McCaffery	NNP
cord-015935-r2wd1yfa	122	18	&	&	CC
cord-015935-r2wd1yfa	122	19	Deutsch	Deutsch	NNP
cord-015935-r2wd1yfa	122	20	,	,	,
cord-015935-r2wd1yfa	122	21	2005	2005	CD
cord-015935-r2wd1yfa	122	22	)	)	-RRB-
cord-015935-r2wd1yfa	122	23	,	,	,
cord-015935-r2wd1yfa	122	24	affecting	affect	VBG
cord-015935-r2wd1yfa	122	25	up	up	IN
cord-015935-r2wd1yfa	122	26	to	to	TO
cord-015935-r2wd1yfa	122	27	20	20	CD
cord-015935-r2wd1yfa	122	28	%	%	NN
cord-015935-r2wd1yfa	122	29	of	of	IN
cord-015935-r2wd1yfa	122	30	all	all	DT
cord-015935-r2wd1yfa	122	31	children	child	NNS
cord-015935-r2wd1yfa	122	32	with	with	IN
cord-015935-r2wd1yfa	122	33	autism	autism	NN
cord-015935-r2wd1yfa	122	34	.	.	.
cord-015935-r2wd1yfa	123	1	Several	several	JJ
cord-015935-r2wd1yfa	123	2	reports	report	NNS
cord-015935-r2wd1yfa	123	3	have	have	VBP
cord-015935-r2wd1yfa	123	4	shown	show	VBN
cord-015935-r2wd1yfa	123	5	increased	increase	VBN
cord-015935-r2wd1yfa	123	6	brain	brain	NN
cord-015935-r2wd1yfa	123	7	volume	volume	NN
cord-015935-r2wd1yfa	123	8	(	(	-LRB-
cord-015935-r2wd1yfa	123	9	macroencephaly	macroencephaly	NNP
cord-015935-r2wd1yfa	123	10	/	/	SYM
cord-015935-r2wd1yfa	123	11	megalencephaly	megalencephaly	NNP
cord-015935-r2wd1yfa	123	12	)	)	-RRB-
cord-015935-r2wd1yfa	123	13	in	in	IN
cord-015935-r2wd1yfa	123	14	both	both	CC
cord-015935-r2wd1yfa	123	15	white	white	JJ
cord-015935-r2wd1yfa	123	16	and	and	CC
cord-015935-r2wd1yfa	123	17	grey	grey	JJ
cord-015935-r2wd1yfa	123	18	matter	matter	NN
cord-015935-r2wd1yfa	123	19	with	with	IN
cord-015935-r2wd1yfa	123	20	results	result	NNS
cord-015935-r2wd1yfa	123	21	varying	vary	VBG
cord-015935-r2wd1yfa	123	22	as	as	IN
cord-015935-r2wd1yfa	123	23	a	a	DT
cord-015935-r2wd1yfa	123	24	function	function	NN
cord-015935-r2wd1yfa	123	25	of	of	IN
cord-015935-r2wd1yfa	123	26	age	age	NN
cord-015935-r2wd1yfa	123	27	.	.	.
cord-015935-r2wd1yfa	124	1	MRI	MRI	NNP
cord-015935-r2wd1yfa	124	2	volumetric	volumetric	JJ
cord-015935-r2wd1yfa	124	3	studies	study	NNS
cord-015935-r2wd1yfa	124	4	have	have	VBP
cord-015935-r2wd1yfa	124	5	showed	show	VBN
cord-015935-r2wd1yfa	124	6	increased	increase	VBN
cord-015935-r2wd1yfa	124	7	brain	brain	NN
cord-015935-r2wd1yfa	124	8	volume	volume	NN
cord-015935-r2wd1yfa	124	9	in	in	IN
cord-015935-r2wd1yfa	124	10	younger	young	JJR
cord-015935-r2wd1yfa	124	11	(	(	-LRB-
cord-015935-r2wd1yfa	124	12	total	total	JJ
cord-015935-r2wd1yfa	124	13	ages	age	NNS
cord-015935-r2wd1yfa	124	14	2	2	CD
cord-015935-r2wd1yfa	124	15	-	-	SYM
cord-015935-r2wd1yfa	124	16	21	21	CD
cord-015935-r2wd1yfa	124	17	)	)	-RRB-
cord-015935-r2wd1yfa	124	18	subjects	subject	NNS
cord-015935-r2wd1yfa	124	19	compared	compare	VBN
cord-015935-r2wd1yfa	124	20	to	to	IN
cord-015935-r2wd1yfa	124	21	older	old	JJR
cord-015935-r2wd1yfa	124	22	(	(	-LRB-
cord-015935-r2wd1yfa	124	23	total	total	JJ
cord-015935-r2wd1yfa	124	24	ages	age	NNS
cord-015935-r2wd1yfa	124	25	5	5	CD
cord-015935-r2wd1yfa	124	26	-	-	SYM
cord-015935-r2wd1yfa	124	27	21	21	CD
cord-015935-r2wd1yfa	124	28	)	)	-RRB-
cord-015935-r2wd1yfa	124	29	subjects	subject	NNS
cord-015935-r2wd1yfa	124	30	(	(	-LRB-
cord-015935-r2wd1yfa	124	31	Courchesne	Courchesne	NNP
cord-015935-r2wd1yfa	124	32	,	,	,
cord-015935-r2wd1yfa	124	33	Carper	Carper	NNP
cord-015935-r2wd1yfa	124	34	,	,	,
cord-015935-r2wd1yfa	124	35	&	&	CC
cord-015935-r2wd1yfa	124	36	Akshoomoff	Akshoomoff	NNP
cord-015935-r2wd1yfa	124	37	,	,	,
cord-015935-r2wd1yfa	124	38	2003	2003	CD
cord-015935-r2wd1yfa	124	39	;	;	:
cord-015935-r2wd1yfa	124	40	Sokol	Sokol	NNP
cord-015935-r2wd1yfa	124	41	&	&	CC
cord-015935-r2wd1yfa	124	42	Edwards	Edwards	NNP
cord-015935-r2wd1yfa	124	43	-	-	HYPH
cord-015935-r2wd1yfa	124	44	Brown	Brown	NNP
cord-015935-r2wd1yfa	124	45	,	,	,
cord-015935-r2wd1yfa	124	46	2004	2004	CD
cord-015935-r2wd1yfa	124	47	;	;	:
cord-015935-r2wd1yfa	124	48	Sparks	Sparks	NNP
cord-015935-r2wd1yfa	124	49	et	et	NNP
cord-015935-r2wd1yfa	124	50	al	al	NNP
cord-015935-r2wd1yfa	124	51	.	.	NNP
cord-015935-r2wd1yfa	124	52	,	,	,
cord-015935-r2wd1yfa	124	53	2002	2002	CD
cord-015935-r2wd1yfa	124	54	)	)	-RRB-
cord-015935-r2wd1yfa	124	55	.	.	.
cord-015935-r2wd1yfa	125	1	To	to	TO
cord-015935-r2wd1yfa	125	2	explain	explain	VB
cord-015935-r2wd1yfa	125	3	the	the	DT
cord-015935-r2wd1yfa	125	4	relevance	relevance	NN
cord-015935-r2wd1yfa	125	5	of	of	IN
cord-015935-r2wd1yfa	125	6	brain	brain	NN
cord-015935-r2wd1yfa	125	7	volume	volume	NN
cord-015935-r2wd1yfa	125	8	enlargement	enlargement	NN
cord-015935-r2wd1yfa	125	9	in	in	IN
cord-015935-r2wd1yfa	125	10	autism	autism	NN
cord-015935-r2wd1yfa	125	11	,	,	,
cord-015935-r2wd1yfa	125	12	it	-PRON-	PRP
cord-015935-r2wd1yfa	125	13	has	have	VBZ
cord-015935-r2wd1yfa	125	14	been	be	VBN
cord-015935-r2wd1yfa	125	15	proposed	propose	VBN
cord-015935-r2wd1yfa	125	16	that	that	DT
cord-015935-r2wd1yfa	125	17	brain	brain	NN
cord-015935-r2wd1yfa	125	18	"	"	''
cord-015935-r2wd1yfa	125	19	growth	growth	NN
cord-015935-r2wd1yfa	125	20	without	without	IN
cord-015935-r2wd1yfa	125	21	guidance	guidance	NN
cord-015935-r2wd1yfa	125	22	"	"	''
cord-015935-r2wd1yfa	125	23	occurs	occur	VBZ
cord-015935-r2wd1yfa	125	24	in	in	IN
cord-015935-r2wd1yfa	125	25	young	young	JJ
cord-015935-r2wd1yfa	125	26	autistic	autistic	JJ
cord-015935-r2wd1yfa	125	27	children	child	NNS
cord-015935-r2wd1yfa	125	28	(	(	-LRB-
cord-015935-r2wd1yfa	125	29	Courchesne	Courchesne	NNP
cord-015935-r2wd1yfa	125	30	et	et	NNP
cord-015935-r2wd1yfa	125	31	al	al	NNP
cord-015935-r2wd1yfa	125	32	.	.	NNP
cord-015935-r2wd1yfa	125	33	,	,	,
cord-015935-r2wd1yfa	125	34	2001	2001	CD
cord-015935-r2wd1yfa	125	35	)	)	-RRB-
cord-015935-r2wd1yfa	125	36	with	with	IN
cord-015935-r2wd1yfa	125	37	premature	premature	JJ
cord-015935-r2wd1yfa	125	38	expansion	expansion	NN
cord-015935-r2wd1yfa	125	39	and	and	CC
cord-015935-r2wd1yfa	125	40	overgrowth	overgrowth	NN
cord-015935-r2wd1yfa	125	41	of	of	IN
cord-015935-r2wd1yfa	125	42	neural	neural	JJ
cord-015935-r2wd1yfa	125	43	elements	element	NNS
cord-015935-r2wd1yfa	125	44	and	and	CC
cord-015935-r2wd1yfa	125	45	dendritic	dendritic	JJ
cord-015935-r2wd1yfa	125	46	connections	connection	NNS
cord-015935-r2wd1yfa	125	47	.	.	.
cord-015935-r2wd1yfa	126	1	Indeed	indeed	RB
cord-015935-r2wd1yfa	126	2	,	,	,
cord-015935-r2wd1yfa	126	3	brain	brain	NN
cord-015935-r2wd1yfa	126	4	enlargement	enlargement	NN
cord-015935-r2wd1yfa	126	5	appears	appear	VBZ
cord-015935-r2wd1yfa	126	6	to	to	TO
cord-015935-r2wd1yfa	126	7	develop	develop	VB
cord-015935-r2wd1yfa	126	8	postnatally	postnatally	NN
cord-015935-r2wd1yfa	126	9	,	,	,
cord-015935-r2wd1yfa	126	10	arising	arise	VBG
cord-015935-r2wd1yfa	126	11	before	before	IN
cord-015935-r2wd1yfa	126	12	or	or	CC
cord-015935-r2wd1yfa	126	13	during	during	IN
cord-015935-r2wd1yfa	126	14	the	the	DT
cord-015935-r2wd1yfa	126	15	early	early	JJ
cord-015935-r2wd1yfa	126	16	recognition	recognition	NN
cord-015935-r2wd1yfa	126	17	of	of	IN
cord-015935-r2wd1yfa	126	18	autistic	autistic	JJ
cord-015935-r2wd1yfa	126	19	behaviors	behavior	NNS
cord-015935-r2wd1yfa	126	20	-between	-between	.
cord-015935-r2wd1yfa	127	1	18	18	CD
cord-015935-r2wd1yfa	127	2	months	month	NNS
cord-015935-r2wd1yfa	127	3	and	and	CC
cord-015935-r2wd1yfa	127	4	3	3	CD
cord-015935-r2wd1yfa	127	5	years	year	NNS
cord-015935-r2wd1yfa	127	6	(	(	-LRB-
cord-015935-r2wd1yfa	127	7	Courchesne	Courchesne	NNP
cord-015935-r2wd1yfa	127	8	et	et	NNP
cord-015935-r2wd1yfa	127	9	al	al	NNP
cord-015935-r2wd1yfa	127	10	.	.	NNP
cord-015935-r2wd1yfa	127	11	,	,	,
cord-015935-r2wd1yfa	127	12	2003	2003	CD
cord-015935-r2wd1yfa	127	13	)	)	-RRB-
cord-015935-r2wd1yfa	127	14	.	.	.
cord-015935-r2wd1yfa	128	1	Proposed	propose	VBN
cord-015935-r2wd1yfa	128	2	mechanisms	mechanism	NNS
cord-015935-r2wd1yfa	128	3	underlying	underlie	VBG
cord-015935-r2wd1yfa	128	4	brain	brain	NN
cord-015935-r2wd1yfa	128	5	enlargement	enlargement	NN
cord-015935-r2wd1yfa	128	6	include	include	VBP
cord-015935-r2wd1yfa	128	7	overproduction	overproduction	NN
cord-015935-r2wd1yfa	128	8	of	of	IN
cord-015935-r2wd1yfa	128	9	synapses	synapsis	NNS
cord-015935-r2wd1yfa	128	10	,	,	,
cord-015935-r2wd1yfa	128	11	failure	failure	NN
cord-015935-r2wd1yfa	128	12	of	of	IN
cord-015935-r2wd1yfa	128	13	synaptic	synaptic	JJ
cord-015935-r2wd1yfa	128	14	pruning	pruning	NN
cord-015935-r2wd1yfa	128	15	,	,	,
cord-015935-r2wd1yfa	128	16	excessive	excessive	JJ
cord-015935-r2wd1yfa	128	17	neurogenesis	neurogenesis	NN
cord-015935-r2wd1yfa	128	18	,	,	,
cord-015935-r2wd1yfa	128	19	gliogenesis	gliogenesis	NN
cord-015935-r2wd1yfa	128	20	,	,	,
cord-015935-r2wd1yfa	128	21	or	or	CC
cord-015935-r2wd1yfa	128	22	reduction	reduction	NN
cord-015935-r2wd1yfa	128	23	in	in	IN
cord-015935-r2wd1yfa	128	24	cell	cell	NN
cord-015935-r2wd1yfa	128	25	death	death	NN
cord-015935-r2wd1yfa	128	26	(	(	-LRB-
cord-015935-r2wd1yfa	128	27	McCaffery	McCaffery	NNP
cord-015935-r2wd1yfa	128	28	&	&	CC
cord-015935-r2wd1yfa	128	29	Deutsch	Deutsch	NNP
cord-015935-r2wd1yfa	128	30	,	,	,
cord-015935-r2wd1yfa	128	31	2005	2005	CD
cord-015935-r2wd1yfa	128	32	)	)	-RRB-
cord-015935-r2wd1yfa	128	33	.	.	.
cord-015935-r2wd1yfa	129	1	The	the	DT
cord-015935-r2wd1yfa	129	2	mechanisms	mechanism	NNS
cord-015935-r2wd1yfa	129	3	underlying	underlie	VBG
cord-015935-r2wd1yfa	129	4	the	the	DT
cord-015935-r2wd1yfa	129	5	tremendous	tremendous	JJ
cord-015935-r2wd1yfa	129	6	growth	growth	NN
cord-015935-r2wd1yfa	129	7	of	of	IN
cord-015935-r2wd1yfa	129	8	the	the	DT
cord-015935-r2wd1yfa	129	9	typically	typically	RB
cord-015935-r2wd1yfa	129	10	developing	develop	VBG
cord-015935-r2wd1yfa	129	11	embryonic	embryonic	JJ
cord-015935-r2wd1yfa	129	12	brain	brain	NN
cord-015935-r2wd1yfa	129	13	,	,	,
cord-015935-r2wd1yfa	129	14	compared	compare	VBN
cord-015935-r2wd1yfa	129	15	to	to	IN
cord-015935-r2wd1yfa	129	16	the	the	DT
cord-015935-r2wd1yfa	129	17	relatively	relatively	RB
cord-015935-r2wd1yfa	129	18	more	more	RBR
cord-015935-r2wd1yfa	129	19	limited	limited	JJ
cord-015935-r2wd1yfa	129	20	postnatal	postnatal	NN
cord-015935-r2wd1yfa	129	21	and	and	CC
cord-015935-r2wd1yfa	129	22	adult	adult	NN
cord-015935-r2wd1yfa	129	23	brain	brain	NN
cord-015935-r2wd1yfa	129	24	growth	growth	NN
cord-015935-r2wd1yfa	129	25	,	,	,
cord-015935-r2wd1yfa	129	26	have	have	VBP
cord-015935-r2wd1yfa	129	27	been	be	VBN
cord-015935-r2wd1yfa	129	28	implicated	implicate	VBN
cord-015935-r2wd1yfa	129	29	in	in	IN
cord-015935-r2wd1yfa	129	30	the	the	DT
cord-015935-r2wd1yfa	129	31	brain	brain	NN
cord-015935-r2wd1yfa	129	32	enlargement	enlargement	NN
cord-015935-r2wd1yfa	129	33	seen	see	VBN
cord-015935-r2wd1yfa	129	34	in	in	IN
cord-015935-r2wd1yfa	129	35	autism	autism	NN
cord-015935-r2wd1yfa	129	36	.	.	.
cord-015935-r2wd1yfa	130	1	This	this	DT
cord-015935-r2wd1yfa	130	2	leads	lead	VBZ
cord-015935-r2wd1yfa	130	3	to	to	IN
cord-015935-r2wd1yfa	130	4	the	the	DT
cord-015935-r2wd1yfa	130	5	proposal	proposal	NN
cord-015935-r2wd1yfa	130	6	that	that	IN
cord-015935-r2wd1yfa	130	7	overstimulation	overstimulation	NN
cord-015935-r2wd1yfa	130	8	of	of	IN
cord-015935-r2wd1yfa	130	9	nuclear	nuclear	JJ
cord-015935-r2wd1yfa	130	10	receptor	receptor	NN
cord-015935-r2wd1yfa	130	11	-	-	HYPH
cord-015935-r2wd1yfa	130	12	mediated	mediate	VBN
cord-015935-r2wd1yfa	130	13	gene	gene	NN
cord-015935-r2wd1yfa	130	14	transcription	transcription	NN
cord-015935-r2wd1yfa	130	15	may	may	MD
cord-015935-r2wd1yfa	130	16	increase	increase	VB
cord-015935-r2wd1yfa	130	17	neural	neural	JJ
cord-015935-r2wd1yfa	130	18	progenitor	progenitor	NN
cord-015935-r2wd1yfa	130	19	cells	cell	NNS
cord-015935-r2wd1yfa	130	20	that	that	WDT
cord-015935-r2wd1yfa	130	21	generate	generate	VBP
cord-015935-r2wd1yfa	130	22	marked	marked	JJ
cord-015935-r2wd1yfa	130	23	increases	increase	NNS
cord-015935-r2wd1yfa	130	24	in	in	IN
cord-015935-r2wd1yfa	130	25	cortical	cortical	JJ
cord-015935-r2wd1yfa	130	26	surface	surface	NN
cord-015935-r2wd1yfa	130	27	area	area	NN
cord-015935-r2wd1yfa	130	28	(	(	-LRB-
cord-015935-r2wd1yfa	130	29	McCaffery	McCaffery	NNP
cord-015935-r2wd1yfa	130	30	&	&	CC
cord-015935-r2wd1yfa	130	31	Deutsch	Deutsch	NNP
cord-015935-r2wd1yfa	130	32	,	,	,
cord-015935-r2wd1yfa	130	33	2005	2005	CD
cord-015935-r2wd1yfa	130	34	)	)	-RRB-
cord-015935-r2wd1yfa	130	35	.	.	.
cord-015935-r2wd1yfa	131	1	Therefore	therefore	RB
cord-015935-r2wd1yfa	131	2	,	,	,
cord-015935-r2wd1yfa	131	3	the	the	DT
cord-015935-r2wd1yfa	131	4	number	number	NN
cord-015935-r2wd1yfa	131	5	of	of	IN
cord-015935-r2wd1yfa	131	6	neurons	neuron	NNS
cord-015935-r2wd1yfa	131	7	in	in	IN
cord-015935-r2wd1yfa	131	8	the	the	DT
cord-015935-r2wd1yfa	131	9	young	young	JJ
cord-015935-r2wd1yfa	131	10	cortex	cortex	NN
cord-015935-r2wd1yfa	131	11	is	be	VBZ
cord-015935-r2wd1yfa	131	12	a	a	DT
cord-015935-r2wd1yfa	131	13	function	function	NN
cord-015935-r2wd1yfa	131	14	of	of	IN
cord-015935-r2wd1yfa	131	15	the	the	DT
cord-015935-r2wd1yfa	131	16	number	number	NN
cord-015935-r2wd1yfa	131	17	of	of	IN
cord-015935-r2wd1yfa	131	18	proliferative	proliferative	JJ
cord-015935-r2wd1yfa	131	19	cells	cell	NNS
cord-015935-r2wd1yfa	131	20	present	present	JJ
cord-015935-r2wd1yfa	131	21	at	at	IN
cord-015935-r2wd1yfa	131	22	the	the	DT
cord-015935-r2wd1yfa	131	23	onset	onset	NN
cord-015935-r2wd1yfa	131	24	of	of	IN
cord-015935-r2wd1yfa	131	25	neurogenesis	neurogenesis	NN
cord-015935-r2wd1yfa	131	26	.	.	.
cord-015935-r2wd1yfa	132	1	Tumor	tumor	NN
cord-015935-r2wd1yfa	132	2	suppressor	suppressor	NN
cord-015935-r2wd1yfa	132	3	genes	gene	NNS
cord-015935-r2wd1yfa	132	4	which	which	WDT
cord-015935-r2wd1yfa	132	5	control	control	VBP
cord-015935-r2wd1yfa	132	6	brain	brain	NN
cord-015935-r2wd1yfa	132	7	growth	growth	NN
cord-015935-r2wd1yfa	132	8	and	and	CC
cord-015935-r2wd1yfa	132	9	migration	migration	NN
cord-015935-r2wd1yfa	132	10	,	,	,
cord-015935-r2wd1yfa	132	11	when	when	WRB
cord-015935-r2wd1yfa	132	12	defective	defective	JJ
cord-015935-r2wd1yfa	132	13	,	,	,
cord-015935-r2wd1yfa	132	14	could	could	MD
cord-015935-r2wd1yfa	132	15	contribute	contribute	VB
cord-015935-r2wd1yfa	132	16	to	to	IN
cord-015935-r2wd1yfa	132	17	macrocephaly	macrocephaly	NNP
cord-015935-r2wd1yfa	132	18	of	of	IN
cord-015935-r2wd1yfa	132	19	failure	failure	NN
cord-015935-r2wd1yfa	132	20	in	in	IN
cord-015935-r2wd1yfa	132	21	synaptic	synaptic	JJ
cord-015935-r2wd1yfa	132	22	pruning	pruning	NN
cord-015935-r2wd1yfa	132	23	.	.	.
cord-015935-r2wd1yfa	133	1	This	this	DT
cord-015935-r2wd1yfa	133	2	explains	explain	VBZ
cord-015935-r2wd1yfa	133	3	the	the	DT
cord-015935-r2wd1yfa	133	4	great	great	JJ
cord-015935-r2wd1yfa	133	5	interest	interest	NN
cord-015935-r2wd1yfa	133	6	in	in	IN
cord-015935-r2wd1yfa	133	7	tumor	tumor	NN
cord-015935-r2wd1yfa	133	8	suppressor	suppressor	NN
cord-015935-r2wd1yfa	133	9	genes	gene	NNS
cord-015935-r2wd1yfa	133	10	such	such	JJ
cord-015935-r2wd1yfa	133	11	as	as	IN
cord-015935-r2wd1yfa	133	12	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	133	13	as	as	IN
cord-015935-r2wd1yfa	133	14	candidate	candidate	NN
cord-015935-r2wd1yfa	133	15	genes	gene	NNS
cord-015935-r2wd1yfa	133	16	for	for	IN
cord-015935-r2wd1yfa	133	17	autism	autism	NN
cord-015935-r2wd1yfa	133	18	.	.	.
cord-015935-r2wd1yfa	134	1	Recently	recently	RB
cord-015935-r2wd1yfa	134	2	,	,	,
cord-015935-r2wd1yfa	134	3	neuronal	neuronal	JJ
cord-015935-r2wd1yfa	134	4	cell	cell	NN
cord-015935-r2wd1yfa	134	5	adhesion	adhesion	NN
cord-015935-r2wd1yfa	134	6	has	have	VBZ
cord-015935-r2wd1yfa	134	7	been	be	VBN
cord-015935-r2wd1yfa	134	8	proposed	propose	VBN
cord-015935-r2wd1yfa	134	9	as	as	IN
cord-015935-r2wd1yfa	134	10	another	another	DT
cord-015935-r2wd1yfa	134	11	mechanism	mechanism	NN
cord-015935-r2wd1yfa	134	12	involved	involve	VBN
cord-015935-r2wd1yfa	134	13	in	in	IN
cord-015935-r2wd1yfa	134	14	brain	brain	NN
cord-015935-r2wd1yfa	134	15	overgrowth	overgrowth	NN
cord-015935-r2wd1yfa	134	16	in	in	IN
cord-015935-r2wd1yfa	134	17	autism	autism	NN
cord-015935-r2wd1yfa	134	18	.	.	.
cord-015935-r2wd1yfa	135	1	Cell	cell	NN
cord-015935-r2wd1yfa	135	2	adhesion	adhesion	NN
cord-015935-r2wd1yfa	135	3	suppresses	suppress	VBZ
cord-015935-r2wd1yfa	135	4	brain	brain	NN
cord-015935-r2wd1yfa	135	5	growth	growth	NN
cord-015935-r2wd1yfa	135	6	,	,	,
cord-015935-r2wd1yfa	135	7	while	while	IN
cord-015935-r2wd1yfa	135	8	abnormalities	abnormality	NNS
cord-015935-r2wd1yfa	135	9	in	in	IN
cord-015935-r2wd1yfa	135	10	adhesion	adhesion	NN
cord-015935-r2wd1yfa	135	11	promote	promote	VBP
cord-015935-r2wd1yfa	135	12	growth	growth	NN
cord-015935-r2wd1yfa	135	13	or	or	CC
cord-015935-r2wd1yfa	135	14	contribute	contribute	VB
cord-015935-r2wd1yfa	135	15	to	to	IN
cord-015935-r2wd1yfa	135	16	aberrant	aberrant	JJ
cord-015935-r2wd1yfa	135	17	growth	growth	NN
cord-015935-r2wd1yfa	135	18	.	.	.
cord-015935-r2wd1yfa	136	1	It	-PRON-	PRP
cord-015935-r2wd1yfa	136	2	is	be	VBZ
cord-015935-r2wd1yfa	136	3	believed	believe	VBN
cord-015935-r2wd1yfa	136	4	that	that	IN
cord-015935-r2wd1yfa	136	5	heterogeneous	heterogeneous	JJ
cord-015935-r2wd1yfa	136	6	causes	cause	NNS
cord-015935-r2wd1yfa	136	7	of	of	IN
cord-015935-r2wd1yfa	136	8	autism	autism	NN
cord-015935-r2wd1yfa	136	9	may	may	MD
cord-015935-r2wd1yfa	136	10	be	be	VB
cord-015935-r2wd1yfa	136	11	associated	associate	VBN
cord-015935-r2wd1yfa	136	12	with	with	IN
cord-015935-r2wd1yfa	136	13	alterations	alteration	NNS
cord-015935-r2wd1yfa	136	14	in	in	IN
cord-015935-r2wd1yfa	136	15	adhesion	adhesion	NN
cord-015935-r2wd1yfa	136	16	molecules	molecule	NNS
cord-015935-r2wd1yfa	136	17	of	of	IN
cord-015935-r2wd1yfa	136	18	the	the	DT
cord-015935-r2wd1yfa	136	19	synapse	synapse	NN
cord-015935-r2wd1yfa	136	20	or	or	CC
cord-015935-r2wd1yfa	136	21	cytoplasmic	cytoplasmic	JJ
cord-015935-r2wd1yfa	136	22	molecules	molecule	NNS
cord-015935-r2wd1yfa	136	23	associated	associate	VBN
cord-015935-r2wd1yfa	136	24	with	with	IN
cord-015935-r2wd1yfa	136	25	synaptic	synaptic	JJ
cord-015935-r2wd1yfa	136	26	receptors	receptor	NNS
cord-015935-r2wd1yfa	136	27	.	.	.
cord-015935-r2wd1yfa	137	1	Indeed	indeed	RB
cord-015935-r2wd1yfa	137	2	,	,	,
cord-015935-r2wd1yfa	137	3	recent	recent	JJ
cord-015935-r2wd1yfa	137	4	genetic	genetic	JJ
cord-015935-r2wd1yfa	137	5	evidence	evidence	NN
cord-015935-r2wd1yfa	137	6	has	have	VBZ
cord-015935-r2wd1yfa	137	7	found	find	VBN
cord-015935-r2wd1yfa	137	8	associations	association	NNS
cord-015935-r2wd1yfa	137	9	between	between	IN
cord-015935-r2wd1yfa	137	10	autism	autism	NN
cord-015935-r2wd1yfa	137	11	susceptibility	susceptibility	NN
cord-015935-r2wd1yfa	137	12	and	and	CC
cord-015935-r2wd1yfa	137	13	other	other	JJ
cord-015935-r2wd1yfa	137	14	neuronal	neuronal	JJ
cord-015935-r2wd1yfa	137	15	cell	cell	NN
cord-015935-r2wd1yfa	137	16	adhesion	adhesion	NN
cord-015935-r2wd1yfa	137	17	molecules	molecule	NNS
cord-015935-r2wd1yfa	137	18	,	,	,
cord-015935-r2wd1yfa	137	19	such	such	JJ
cord-015935-r2wd1yfa	137	20	as	as	IN
cord-015935-r2wd1yfa	137	21	NLGN1	NLGN1	NNP
cord-015935-r2wd1yfa	137	22	and	and	CC
cord-015935-r2wd1yfa	137	23	ASTN2	ASTN2	NNP
cord-015935-r2wd1yfa	137	24	and	and	CC
cord-015935-r2wd1yfa	137	25	specific	specific	JJ
cord-015935-r2wd1yfa	137	26	cadherins	cadherin	NNS
cord-015935-r2wd1yfa	137	27	.	.	.
cord-015935-r2wd1yfa	138	1	There	there	EX
cord-015935-r2wd1yfa	138	2	is	be	VBZ
cord-015935-r2wd1yfa	138	3	an	an	DT
cord-015935-r2wd1yfa	138	4	emerging	emerge	VBG
cord-015935-r2wd1yfa	138	5	theory	theory	NN
cord-015935-r2wd1yfa	138	6	,	,	,
cord-015935-r2wd1yfa	138	7	as	as	IN
cord-015935-r2wd1yfa	138	8	recently	recently	RB
cord-015935-r2wd1yfa	138	9	reviewed	review	VBN
cord-015935-r2wd1yfa	138	10	in	in	IN
cord-015935-r2wd1yfa	138	11	Geschwind	Geschwind	NNP
cord-015935-r2wd1yfa	138	12	(	(	-LRB-
cord-015935-r2wd1yfa	138	13	2009	2009	CD
cord-015935-r2wd1yfa	138	14	)	)	-RRB-
cord-015935-r2wd1yfa	138	15	,	,	,
cord-015935-r2wd1yfa	138	16	that	that	IN
cord-015935-r2wd1yfa	138	17	short	short	JJ
cord-015935-r2wd1yfa	138	18	-	-	HYPH
cord-015935-r2wd1yfa	138	19	range	range	NN
cord-015935-r2wd1yfa	138	20	brain	brain	NN
cord-015935-r2wd1yfa	138	21	connections	connection	NNS
cord-015935-r2wd1yfa	138	22	may	may	MD
cord-015935-r2wd1yfa	138	23	be	be	VB
cord-015935-r2wd1yfa	138	24	overgrown	overgrown	JJ
cord-015935-r2wd1yfa	138	25	and	and	CC
cord-015935-r2wd1yfa	138	26	longer	long	RBR
cord-015935-r2wd1yfa	138	27	range	range	VBP
cord-015935-r2wd1yfa	138	28	brain	brain	NN
cord-015935-r2wd1yfa	138	29	connections	connection	NNS
cord-015935-r2wd1yfa	138	30	between	between	IN
cord-015935-r2wd1yfa	138	31	different	different	JJ
cord-015935-r2wd1yfa	138	32	brain	brain	NN
cord-015935-r2wd1yfa	138	33	lobules	lobule	NNS
cord-015935-r2wd1yfa	138	34	are	be	VBP
cord-015935-r2wd1yfa	138	35	reduced	reduce	VBN
cord-015935-r2wd1yfa	138	36	in	in	IN
cord-015935-r2wd1yfa	138	37	autism	autism	NN
cord-015935-r2wd1yfa	138	38	.	.	.
cord-015935-r2wd1yfa	139	1	In	in	IN
cord-015935-r2wd1yfa	139	2	autism	autism	NN
cord-015935-r2wd1yfa	139	3	,	,	,
cord-015935-r2wd1yfa	139	4	there	there	EX
cord-015935-r2wd1yfa	139	5	has	have	VBZ
cord-015935-r2wd1yfa	139	6	been	be	VBN
cord-015935-r2wd1yfa	139	7	a	a	DT
cord-015935-r2wd1yfa	139	8	noted	note	VBN
cord-015935-r2wd1yfa	139	9	reduction	reduction	NN
cord-015935-r2wd1yfa	139	10	in	in	IN
cord-015935-r2wd1yfa	139	11	the	the	DT
cord-015935-r2wd1yfa	139	12	size	size	NN
cord-015935-r2wd1yfa	139	13	of	of	IN
cord-015935-r2wd1yfa	139	14	the	the	DT
cord-015935-r2wd1yfa	139	15	corpus	corpus	NNP
cord-015935-r2wd1yfa	139	16	callosum	callosum	NNP
cord-015935-r2wd1yfa	139	17	which	which	WDT
cord-015935-r2wd1yfa	139	18	connects	connect	VBZ
cord-015935-r2wd1yfa	139	19	the	the	DT
cord-015935-r2wd1yfa	139	20	two	two	CD
cord-015935-r2wd1yfa	139	21	cerebral	cerebral	JJ
cord-015935-r2wd1yfa	139	22	hemispheres	hemisphere	NNS
cord-015935-r2wd1yfa	139	23	and	and	CC
cord-015935-r2wd1yfa	139	24	reduced	reduce	VBN
cord-015935-r2wd1yfa	139	25	connectivity	connectivity	NN
cord-015935-r2wd1yfa	139	26	between	between	IN
cord-015935-r2wd1yfa	139	27	the	the	DT
cord-015935-r2wd1yfa	139	28	frontal	frontal	JJ
cord-015935-r2wd1yfa	139	29	and	and	CC
cord-015935-r2wd1yfa	139	30	temporal	temporal	JJ
cord-015935-r2wd1yfa	139	31	lobes	lobe	NNS
cord-015935-r2wd1yfa	139	32	of	of	IN
cord-015935-r2wd1yfa	139	33	the	the	DT
cord-015935-r2wd1yfa	139	34	brain	brain	NN
cord-015935-r2wd1yfa	139	35	,	,	,
cord-015935-r2wd1yfa	139	36	locations	location	NNS
cord-015935-r2wd1yfa	139	37	responsible	responsible	JJ
cord-015935-r2wd1yfa	139	38	for	for	IN
cord-015935-r2wd1yfa	139	39	language	language	NN
cord-015935-r2wd1yfa	139	40	and	and	CC
cord-015935-r2wd1yfa	139	41	social	social	JJ
cord-015935-r2wd1yfa	139	42	judgment	judgment	NN
cord-015935-r2wd1yfa	139	43	.	.	.
cord-015935-r2wd1yfa	140	1	The	the	DT
cord-015935-r2wd1yfa	140	2	preservation	preservation	NN
cord-015935-r2wd1yfa	140	3	of	of	IN
cord-015935-r2wd1yfa	140	4	normal	normal	JJ
cord-015935-r2wd1yfa	140	5	short	short	JJ
cord-015935-r2wd1yfa	140	6	-	-	HYPH
cord-015935-r2wd1yfa	140	7	range	range	NN
cord-015935-r2wd1yfa	140	8	connections	connection	NNS
cord-015935-r2wd1yfa	140	9	could	could	MD
cord-015935-r2wd1yfa	140	10	explain	explain	VB
cord-015935-r2wd1yfa	140	11	some	some	DT
cord-015935-r2wd1yfa	140	12	of	of	IN
cord-015935-r2wd1yfa	140	13	the	the	DT
cord-015935-r2wd1yfa	140	14	preserved	preserve	VBN
cord-015935-r2wd1yfa	140	15	processing	processing	NN
cord-015935-r2wd1yfa	140	16	functions	function	NNS
cord-015935-r2wd1yfa	140	17	such	such	JJ
cord-015935-r2wd1yfa	140	18	as	as	IN
cord-015935-r2wd1yfa	140	19	visual	visual	JJ
cord-015935-r2wd1yfa	140	20	perception	perception	NN
cord-015935-r2wd1yfa	140	21	or	or	CC
cord-015935-r2wd1yfa	140	22	attention	attention	NN
cord-015935-r2wd1yfa	140	23	to	to	TO
cord-015935-r2wd1yfa	140	24	detail	detail	NN
cord-015935-r2wd1yfa	140	25	experienced	experience	VBN
cord-015935-r2wd1yfa	140	26	by	by	IN
cord-015935-r2wd1yfa	140	27	many	many	JJ
cord-015935-r2wd1yfa	140	28	with	with	IN
cord-015935-r2wd1yfa	140	29	autism	autism	NN
cord-015935-r2wd1yfa	140	30	(	(	-LRB-
cord-015935-r2wd1yfa	140	31	Geschwind	Geschwind	NNP
cord-015935-r2wd1yfa	140	32	,	,	,
cord-015935-r2wd1yfa	140	33	2009	2009	CD
cord-015935-r2wd1yfa	140	34	)	)	-RRB-
cord-015935-r2wd1yfa	140	35	.	.	.
cord-015935-r2wd1yfa	141	1	Three	three	CD
cord-015935-r2wd1yfa	141	2	lines	line	NNS
cord-015935-r2wd1yfa	141	3	of	of	IN
cord-015935-r2wd1yfa	141	4	research	research	NN
cord-015935-r2wd1yfa	141	5	indirectly	indirectly	RB
cord-015935-r2wd1yfa	141	6	attest	attest	VBP
cord-015935-r2wd1yfa	141	7	to	to	IN
cord-015935-r2wd1yfa	141	8	the	the	DT
cord-015935-r2wd1yfa	141	9	heritability	heritability	NN
cord-015935-r2wd1yfa	141	10	of	of	IN
cord-015935-r2wd1yfa	141	11	autism	autism	NNP
cord-015935-r2wd1yfa	141	12	:	:	:
cord-015935-r2wd1yfa	141	13	twin	twin	JJ
cord-015935-r2wd1yfa	141	14	studies	study	NNS
cord-015935-r2wd1yfa	141	15	,	,	,
cord-015935-r2wd1yfa	141	16	family	family	NN
cord-015935-r2wd1yfa	141	17	studies	study	NNS
cord-015935-r2wd1yfa	141	18	,	,	,
cord-015935-r2wd1yfa	141	19	and	and	CC
cord-015935-r2wd1yfa	141	20	the	the	DT
cord-015935-r2wd1yfa	141	21	fact	fact	NN
cord-015935-r2wd1yfa	141	22	that	that	IN
cord-015935-r2wd1yfa	141	23	autism	autism	NN
cord-015935-r2wd1yfa	141	24	affects	affect	VBZ
cord-015935-r2wd1yfa	141	25	more	more	JJR
cord-015935-r2wd1yfa	141	26	boys	boy	NNS
cord-015935-r2wd1yfa	141	27	than	than	IN
cord-015935-r2wd1yfa	141	28	girls	girl	NNS
cord-015935-r2wd1yfa	141	29	.	.	.
cord-015935-r2wd1yfa	142	1	In	in	IN
cord-015935-r2wd1yfa	142	2	general	general	JJ
cord-015935-r2wd1yfa	142	3	,	,	,
cord-015935-r2wd1yfa	142	4	hereditability	hereditability	NN
cord-015935-r2wd1yfa	142	5	appears	appear	VBZ
cord-015935-r2wd1yfa	142	6	to	to	TO
cord-015935-r2wd1yfa	142	7	be	be	VB
cord-015935-r2wd1yfa	142	8	greater	great	JJR
cord-015935-r2wd1yfa	142	9	when	when	WRB
cord-015935-r2wd1yfa	142	10	a	a	DT
cord-015935-r2wd1yfa	142	11	broader	broad	JJR
cord-015935-r2wd1yfa	142	12	definition	definition	NN
cord-015935-r2wd1yfa	142	13	of	of	IN
cord-015935-r2wd1yfa	142	14	autism	autism	NN
cord-015935-r2wd1yfa	142	15	(	(	-LRB-
cord-015935-r2wd1yfa	142	16	including	include	VBG
cord-015935-r2wd1yfa	142	17	individuals	individual	NNS
cord-015935-r2wd1yfa	142	18	with	with	IN
cord-015935-r2wd1yfa	142	19	cognitive	cognitive	JJ
cord-015935-r2wd1yfa	142	20	deficits	deficit	NNS
cord-015935-r2wd1yfa	142	21	and/or	and/or	CC
cord-015935-r2wd1yfa	142	22	social	social	JJ
cord-015935-r2wd1yfa	142	23	impairment	impairment	NN
cord-015935-r2wd1yfa	142	24	)	)	-RRB-
cord-015935-r2wd1yfa	142	25	instead	instead	RB
cord-015935-r2wd1yfa	142	26	of	of	IN
cord-015935-r2wd1yfa	142	27	the	the	DT
cord-015935-r2wd1yfa	142	28	specific	specific	JJ
cord-015935-r2wd1yfa	142	29	DSM	DSM	NNP
cord-015935-r2wd1yfa	142	30	-	-	HYPH
cord-015935-r2wd1yfa	142	31	IV	IV	NNP
cord-015935-r2wd1yfa	142	32	criteria	criterion	NNS
cord-015935-r2wd1yfa	142	33	for	for	IN
cord-015935-r2wd1yfa	142	34	autism	autism	NN
cord-015935-r2wd1yfa	142	35	is	be	VBZ
cord-015935-r2wd1yfa	142	36	used	use	VBN
cord-015935-r2wd1yfa	142	37	.	.	.
cord-015935-r2wd1yfa	143	1	In	in	IN
cord-015935-r2wd1yfa	143	2	the	the	DT
cord-015935-r2wd1yfa	143	3	first	first	JJ
cord-015935-r2wd1yfa	143	4	twin	twin	JJ
cord-015935-r2wd1yfa	143	5	study	study	NN
cord-015935-r2wd1yfa	143	6	of	of	IN
cord-015935-r2wd1yfa	143	7	autism	autism	NN
cord-015935-r2wd1yfa	143	8	(	(	-LRB-
cord-015935-r2wd1yfa	143	9	Folstein	Folstein	NNP
cord-015935-r2wd1yfa	143	10	&	&	CC
cord-015935-r2wd1yfa	143	11	Rutter	Rutter	NNP
cord-015935-r2wd1yfa	143	12	,	,	,
cord-015935-r2wd1yfa	143	13	1977	1977	CD
cord-015935-r2wd1yfa	143	14	)	)	-RRB-
cord-015935-r2wd1yfa	143	15	,	,	,
cord-015935-r2wd1yfa	143	16	the	the	DT
cord-015935-r2wd1yfa	143	17	concordance	concordance	NN
cord-015935-r2wd1yfa	143	18	rate	rate	NN
cord-015935-r2wd1yfa	143	19	in	in	IN
cord-015935-r2wd1yfa	143	20	monozygotic	monozygotic	NNS
cord-015935-r2wd1yfa	143	21	(	(	-LRB-
cord-015935-r2wd1yfa	143	22	MZ	MZ	NNP
cord-015935-r2wd1yfa	143	23	)	)	-RRB-
cord-015935-r2wd1yfa	143	24	pairs	pair	NNS
cord-015935-r2wd1yfa	143	25	(	(	-LRB-
cord-015935-r2wd1yfa	143	26	36	36	CD
cord-015935-r2wd1yfa	143	27	%	%	NN
cord-015935-r2wd1yfa	143	28	)	)	-RRB-
cord-015935-r2wd1yfa	143	29	was	be	VBD
cord-015935-r2wd1yfa	143	30	significantly	significantly	RB
cord-015935-r2wd1yfa	143	31	greater	great	JJR
cord-015935-r2wd1yfa	143	32	than	than	IN
cord-015935-r2wd1yfa	143	33	that	that	DT
cord-015935-r2wd1yfa	143	34	found	find	VBN
cord-015935-r2wd1yfa	143	35	in	in	IN
cord-015935-r2wd1yfa	143	36	dizygotic	dizygotic	JJ
cord-015935-r2wd1yfa	143	37	(	(	-LRB-
cord-015935-r2wd1yfa	143	38	DZ	DZ	NNP
cord-015935-r2wd1yfa	143	39	)	)	-RRB-
cord-015935-r2wd1yfa	143	40	pairs	pair	NNS
cord-015935-r2wd1yfa	143	41	(	(	-LRB-
cord-015935-r2wd1yfa	143	42	0	0	CD
cord-015935-r2wd1yfa	143	43	%	%	NN
cord-015935-r2wd1yfa	143	44	)	)	-RRB-
cord-015935-r2wd1yfa	143	45	.	.	.
cord-015935-r2wd1yfa	144	1	If	if	IN
cord-015935-r2wd1yfa	144	2	the	the	DT
cord-015935-r2wd1yfa	144	3	phenotype	phenotype	NN
cord-015935-r2wd1yfa	144	4	was	be	VBD
cord-015935-r2wd1yfa	144	5	expanded	expand	VBN
cord-015935-r2wd1yfa	144	6	to	to	TO
cord-015935-r2wd1yfa	144	7	include	include	VB
cord-015935-r2wd1yfa	144	8	a	a	DT
cord-015935-r2wd1yfa	144	9	cognitive	cognitive	NN
cord-015935-r2wd1yfa	144	10	or	or	CC
cord-015935-r2wd1yfa	144	11	a	a	DT
cord-015935-r2wd1yfa	144	12	language	language	NN
cord-015935-r2wd1yfa	144	13	disorder	disorder	NN
cord-015935-r2wd1yfa	144	14	,	,	,
cord-015935-r2wd1yfa	144	15	the	the	DT
cord-015935-r2wd1yfa	144	16	concordance	concordance	NN
cord-015935-r2wd1yfa	144	17	rates	rate	NNS
cord-015935-r2wd1yfa	144	18	were	be	VBD
cord-015935-r2wd1yfa	144	19	82	82	CD
cord-015935-r2wd1yfa	144	20	and	and	CC
cord-015935-r2wd1yfa	144	21	10	10	CD
cord-015935-r2wd1yfa	144	22	%	%	NN
cord-015935-r2wd1yfa	144	23	,	,	,
cord-015935-r2wd1yfa	144	24	respectively	respectively	RB
cord-015935-r2wd1yfa	144	25	.	.	.
cord-015935-r2wd1yfa	145	1	Two	two	CD
cord-015935-r2wd1yfa	145	2	subsequent	subsequent	JJ
cord-015935-r2wd1yfa	145	3	studies	study	NNS
cord-015935-r2wd1yfa	145	4	found	find	VBD
cord-015935-r2wd1yfa	145	5	an	an	DT
cord-015935-r2wd1yfa	145	6	MZ	MZ	NNP
cord-015935-r2wd1yfa	145	7	/	/	SYM
cord-015935-r2wd1yfa	145	8	DZ	dz	NN
cord-015935-r2wd1yfa	145	9	concordance	concordance	NN
cord-015935-r2wd1yfa	145	10	rate	rate	NN
cord-015935-r2wd1yfa	145	11	of	of	IN
cord-015935-r2wd1yfa	145	12	91	91	CD
cord-015935-r2wd1yfa	145	13	-	-	SYM
cord-015935-r2wd1yfa	145	14	0	0	CD
cord-015935-r2wd1yfa	145	15	%	%	NN
cord-015935-r2wd1yfa	145	16	(	(	-LRB-
cord-015935-r2wd1yfa	145	17	Steffenburg	Steffenburg	NNP
cord-015935-r2wd1yfa	145	18	et	et	NNP
cord-015935-r2wd1yfa	145	19	al	al	NNP
cord-015935-r2wd1yfa	145	20	.	.	NNP
cord-015935-r2wd1yfa	145	21	,	,	,
cord-015935-r2wd1yfa	145	22	1989	1989	CD
cord-015935-r2wd1yfa	145	23	)	)	-RRB-
cord-015935-r2wd1yfa	145	24	or	or	CC
cord-015935-r2wd1yfa	145	25	60	60	CD
cord-015935-r2wd1yfa	145	26	-	-	SYM
cord-015935-r2wd1yfa	145	27	5	5	CD
cord-015935-r2wd1yfa	145	28	%	%	NN
cord-015935-r2wd1yfa	145	29	utilizing	utilize	VBG
cord-015935-r2wd1yfa	145	30	the	the	DT
cord-015935-r2wd1yfa	145	31	specific	specific	JJ
cord-015935-r2wd1yfa	145	32	phenotype	phenotype	NN
cord-015935-r2wd1yfa	145	33	,	,	,
cord-015935-r2wd1yfa	145	34	and	and	CC
cord-015935-r2wd1yfa	145	35	90	90	CD
cord-015935-r2wd1yfa	145	36	%	%	NN
cord-015935-r2wd1yfa	145	37	vs.	vs.	CC
cord-015935-r2wd1yfa	145	38	10	10	CD
cord-015935-r2wd1yfa	145	39	%	%	NN
cord-015935-r2wd1yfa	145	40	using	use	VBG
cord-015935-r2wd1yfa	145	41	the	the	DT
cord-015935-r2wd1yfa	145	42	broader	broad	JJR
cord-015935-r2wd1yfa	145	43	phenotype	phenotype	NN
cord-015935-r2wd1yfa	145	44	which	which	WDT
cord-015935-r2wd1yfa	145	45	included	include	VBD
cord-015935-r2wd1yfa	145	46	social	social	JJ
cord-015935-r2wd1yfa	145	47	or	or	CC
cord-015935-r2wd1yfa	145	48	cognitive	cognitive	JJ
cord-015935-r2wd1yfa	145	49	deficits	deficit	NNS
cord-015935-r2wd1yfa	145	50	.	.	.
cord-015935-r2wd1yfa	146	1	Across	across	IN
cord-015935-r2wd1yfa	146	2	twin	twin	JJ
cord-015935-r2wd1yfa	146	3	studies	study	NNS
cord-015935-r2wd1yfa	146	4	of	of	IN
cord-015935-r2wd1yfa	146	5	autism	autism	NN
cord-015935-r2wd1yfa	146	6	,	,	,
cord-015935-r2wd1yfa	146	7	the	the	DT
cord-015935-r2wd1yfa	146	8	difference	difference	NN
cord-015935-r2wd1yfa	146	9	between	between	IN
cord-015935-r2wd1yfa	146	10	MZ	MZ	NNP
cord-015935-r2wd1yfa	146	11	and	and	CC
cord-015935-r2wd1yfa	146	12	DZ	DZ	NNP
cord-015935-r2wd1yfa	146	13	concordance	concordance	NN
cord-015935-r2wd1yfa	146	14	rates	rate	NNS
cord-015935-r2wd1yfa	146	15	is	be	VBZ
cord-015935-r2wd1yfa	146	16	sizable	sizable	JJ
cord-015935-r2wd1yfa	146	17	,	,	,
cord-015935-r2wd1yfa	146	18	averaging	average	VBG
cord-015935-r2wd1yfa	146	19	roughly	roughly	RB
cord-015935-r2wd1yfa	146	20	10:1	10:1	CD
cord-015935-r2wd1yfa	146	21	(	(	-LRB-
cord-015935-r2wd1yfa	146	22	Pennington	Pennington	NNP
cord-015935-r2wd1yfa	146	23	,	,	,
cord-015935-r2wd1yfa	146	24	2009	2009	CD
cord-015935-r2wd1yfa	146	25	)	)	-RRB-
cord-015935-r2wd1yfa	146	26	.	.	.
cord-015935-r2wd1yfa	147	1	This	this	DT
cord-015935-r2wd1yfa	147	2	rate	rate	NN
cord-015935-r2wd1yfa	147	3	is	be	VBZ
cord-015935-r2wd1yfa	147	4	greater	great	JJR
cord-015935-r2wd1yfa	147	5	than	than	IN
cord-015935-r2wd1yfa	147	6	that	that	DT
cord-015935-r2wd1yfa	147	7	for	for	IN
cord-015935-r2wd1yfa	147	8	other	other	JJ
cord-015935-r2wd1yfa	147	9	psychiatric	psychiatric	JJ
cord-015935-r2wd1yfa	147	10	disorders	disorder	NNS
cord-015935-r2wd1yfa	147	11	such	such	JJ
cord-015935-r2wd1yfa	147	12	as	as	IN
cord-015935-r2wd1yfa	147	13	depression	depression	NN
cord-015935-r2wd1yfa	147	14	,	,	,
cord-015935-r2wd1yfa	147	15	bipolar	bipolar	JJ
cord-015935-r2wd1yfa	147	16	disorder	disorder	NN
cord-015935-r2wd1yfa	147	17	,	,	,
cord-015935-r2wd1yfa	147	18	and	and	CC
cord-015935-r2wd1yfa	147	19	schizophrenia	schizophrenia	NN
cord-015935-r2wd1yfa	147	20	(	(	-LRB-
cord-015935-r2wd1yfa	147	21	between	between	IN
cord-015935-r2wd1yfa	147	22	2:1	2:1	CD
cord-015935-r2wd1yfa	147	23	and	and	CC
cord-015935-r2wd1yfa	147	24	4:1	4:1	CD
cord-015935-r2wd1yfa	147	25	)	)	-RRB-
cord-015935-r2wd1yfa	147	26	,	,	,
cord-015935-r2wd1yfa	147	27	indicating	indicate	VBG
cord-015935-r2wd1yfa	147	28	a	a	DT
cord-015935-r2wd1yfa	147	29	high	high	JJ
cord-015935-r2wd1yfa	147	30	heritability	heritability	NN
cord-015935-r2wd1yfa	147	31	for	for	IN
cord-015935-r2wd1yfa	147	32	autism	autism	NN
cord-015935-r2wd1yfa	147	33	(	(	-LRB-
cord-015935-r2wd1yfa	147	34	Pennington	Pennington	NNP
cord-015935-r2wd1yfa	147	35	,	,	,
cord-015935-r2wd1yfa	147	36	2009	2009	CD
cord-015935-r2wd1yfa	147	37	)	)	-RRB-
cord-015935-r2wd1yfa	147	38	.	.	.
cord-015935-r2wd1yfa	148	1	On	on	IN
cord-015935-r2wd1yfa	148	2	the	the	DT
cord-015935-r2wd1yfa	148	3	other	other	JJ
cord-015935-r2wd1yfa	148	4	hand	hand	NN
cord-015935-r2wd1yfa	148	5	,	,	,
cord-015935-r2wd1yfa	148	6	there	there	EX
cord-015935-r2wd1yfa	148	7	was	be	VBD
cord-015935-r2wd1yfa	148	8	great	great	JJ
cord-015935-r2wd1yfa	148	9	variability	variability	NN
cord-015935-r2wd1yfa	148	10	in	in	IN
cord-015935-r2wd1yfa	148	11	IQ	iq	NN
cord-015935-r2wd1yfa	148	12	and	and	CC
cord-015935-r2wd1yfa	148	13	clinical	clinical	JJ
cord-015935-r2wd1yfa	148	14	behaviors	behavior	NNS
cord-015935-r2wd1yfa	148	15	in	in	IN
cord-015935-r2wd1yfa	148	16	the	the	DT
cord-015935-r2wd1yfa	148	17	16	16	CD
cord-015935-r2wd1yfa	148	18	MZ	MZ	NNP
cord-015935-r2wd1yfa	148	19	pairs	pair	NNS
cord-015935-r2wd1yfa	148	20	concordant	concordant	JJ
cord-015935-r2wd1yfa	148	21	for	for	IN
cord-015935-r2wd1yfa	148	22	autism	autism	NN
cord-015935-r2wd1yfa	148	23	in	in	IN
cord-015935-r2wd1yfa	148	24	the	the	DT
cord-015935-r2wd1yfa	148	25	study	study	NN
cord-015935-r2wd1yfa	148	26	.	.	.
cord-015935-r2wd1yfa	149	1	In	in	IN
cord-015935-r2wd1yfa	149	2	other	other	JJ
cord-015935-r2wd1yfa	149	3	words	word	NNS
cord-015935-r2wd1yfa	149	4	,	,	,
cord-015935-r2wd1yfa	149	5	there	there	EX
cord-015935-r2wd1yfa	149	6	was	be	VBD
cord-015935-r2wd1yfa	149	7	no	no	DT
cord-015935-r2wd1yfa	149	8	more	more	JJR
cord-015935-r2wd1yfa	149	9	similarity	similarity	NN
cord-015935-r2wd1yfa	149	10	for	for	IN
cord-015935-r2wd1yfa	149	11	these	these	DT
cord-015935-r2wd1yfa	149	12	traits	trait	NNS
cord-015935-r2wd1yfa	149	13	within	within	IN
cord-015935-r2wd1yfa	149	14	MZ	MZ	NNP
cord-015935-r2wd1yfa	149	15	pairs	pair	NNS
cord-015935-r2wd1yfa	149	16	than	than	IN
cord-015935-r2wd1yfa	149	17	that	that	DT
cord-015935-r2wd1yfa	149	18	between	between	IN
cord-015935-r2wd1yfa	149	19	individuals	individual	NNS
cord-015935-r2wd1yfa	149	20	picked	pick	VBN
cord-015935-r2wd1yfa	149	21	at	at	IN
cord-015935-r2wd1yfa	149	22	random	random	JJ
cord-015935-r2wd1yfa	149	23	from	from	IN
cord-015935-r2wd1yfa	149	24	different	different	JJ
cord-015935-r2wd1yfa	149	25	MZ	MZ	NNP
cord-015935-r2wd1yfa	149	26	pairs	pair	NNS
cord-015935-r2wd1yfa	149	27	who	who	WP
cord-015935-r2wd1yfa	149	28	also	also	RB
cord-015935-r2wd1yfa	149	29	had	have	VBD
cord-015935-r2wd1yfa	149	30	autism	autism	NN
cord-015935-r2wd1yfa	149	31	.	.	.
cord-015935-r2wd1yfa	150	1	As	as	IN
cord-015935-r2wd1yfa	150	2	interpreted	interpret	VBN
cord-015935-r2wd1yfa	150	3	by	by	IN
cord-015935-r2wd1yfa	150	4	Pennington	Pennington	NNP
cord-015935-r2wd1yfa	150	5	(	(	-LRB-
cord-015935-r2wd1yfa	150	6	2009	2009	CD
cord-015935-r2wd1yfa	150	7	)	)	-RRB-
cord-015935-r2wd1yfa	150	8	,	,	,
cord-015935-r2wd1yfa	150	9	this	this	DT
cord-015935-r2wd1yfa	150	10	finding	finding	NN
cord-015935-r2wd1yfa	150	11	suggests	suggest	VBZ
cord-015935-r2wd1yfa	150	12	that	that	IN
cord-015935-r2wd1yfa	150	13	although	although	IN
cord-015935-r2wd1yfa	150	14	autism	autism	NN
cord-015935-r2wd1yfa	150	15	is	be	VBZ
cord-015935-r2wd1yfa	150	16	heritable	heritable	JJ
cord-015935-r2wd1yfa	150	17	,	,	,
cord-015935-r2wd1yfa	150	18	the	the	DT
cord-015935-r2wd1yfa	150	19	genes	gene	NNS
cord-015935-r2wd1yfa	150	20	may	may	MD
cord-015935-r2wd1yfa	150	21	not	not	RB
cord-015935-r2wd1yfa	150	22	dictate	dictate	VB
cord-015935-r2wd1yfa	150	23	the	the	DT
cord-015935-r2wd1yfa	150	24	exact	exact	JJ
cord-015935-r2wd1yfa	150	25	phenotype	phenotype	NN
cord-015935-r2wd1yfa	150	26	.	.	.
cord-015935-r2wd1yfa	151	1	Nonadditive	nonadditive	JJ
cord-015935-r2wd1yfa	151	2	interaction	interaction	NN
cord-015935-r2wd1yfa	151	3	among	among	IN
cord-015935-r2wd1yfa	151	4	genes	gene	NNS
cord-015935-r2wd1yfa	151	5	(	(	-LRB-
cord-015935-r2wd1yfa	151	6	epistasis	epistasis	NN
cord-015935-r2wd1yfa	151	7	)	)	-RRB-
cord-015935-r2wd1yfa	151	8	and	and	CC
cord-015935-r2wd1yfa	151	9	nonshared	nonshare	VBN
cord-015935-r2wd1yfa	151	10	environmental	environmental	JJ
cord-015935-r2wd1yfa	151	11	influences	influence	NNS
cord-015935-r2wd1yfa	151	12	likely	likely	RB
cord-015935-r2wd1yfa	151	13	contribute	contribute	VBP
cord-015935-r2wd1yfa	151	14	to	to	IN
cord-015935-r2wd1yfa	151	15	these	these	DT
cord-015935-r2wd1yfa	151	16	differences	difference	NNS
cord-015935-r2wd1yfa	151	17	in	in	IN
cord-015935-r2wd1yfa	151	18	phenotypes	phenotype	NNS
cord-015935-r2wd1yfa	151	19	.	.	.
cord-015935-r2wd1yfa	152	1	Further	further	RB
cord-015935-r2wd1yfa	152	2	,	,	,
cord-015935-r2wd1yfa	152	3	the	the	DT
cord-015935-r2wd1yfa	152	4	large	large	JJ
cord-015935-r2wd1yfa	152	5	disparity	disparity	NN
cord-015935-r2wd1yfa	152	6	between	between	IN
cord-015935-r2wd1yfa	152	7	the	the	DT
cord-015935-r2wd1yfa	152	8	MZ	MZ	NNP
cord-015935-r2wd1yfa	152	9	and	and	CC
cord-015935-r2wd1yfa	152	10	the	the	DT
cord-015935-r2wd1yfa	152	11	DZ	DZ	NNP
cord-015935-r2wd1yfa	152	12	concordance	concordance	NN
cord-015935-r2wd1yfa	152	13	rates	rate	NNS
cord-015935-r2wd1yfa	152	14	has	have	VBZ
cord-015935-r2wd1yfa	152	15	been	be	VBN
cord-015935-r2wd1yfa	152	16	attributed	attribute	VBN
cord-015935-r2wd1yfa	152	17	to	to	IN
cord-015935-r2wd1yfa	152	18	epistasis	epistasis	NN
cord-015935-r2wd1yfa	152	19	(	(	-LRB-
cord-015935-r2wd1yfa	152	20	Pennington	Pennington	NNP
cord-015935-r2wd1yfa	152	21	,	,	,
cord-015935-r2wd1yfa	152	22	2009	2009	CD
cord-015935-r2wd1yfa	152	23	)	)	-RRB-
cord-015935-r2wd1yfa	152	24	.	.	.
cord-015935-r2wd1yfa	153	1	Alternatively	alternatively	RB
cord-015935-r2wd1yfa	153	2	,	,	,
cord-015935-r2wd1yfa	153	3	rare	rare	JJ
cord-015935-r2wd1yfa	153	4	gene	gene	NN
cord-015935-r2wd1yfa	153	5	variants	variant	NNS
cord-015935-r2wd1yfa	153	6	causing	cause	VBG
cord-015935-r2wd1yfa	153	7	a	a	DT
cord-015935-r2wd1yfa	153	8	common	common	JJ
cord-015935-r2wd1yfa	153	9	disorder	disorder	NN
cord-015935-r2wd1yfa	153	10	(	(	-LRB-
cord-015935-r2wd1yfa	153	11	autism	autism	NN
cord-015935-r2wd1yfa	153	12	)	)	-RRB-
cord-015935-r2wd1yfa	153	13	,	,	,
cord-015935-r2wd1yfa	153	14	as	as	IN
cord-015935-r2wd1yfa	153	15	described	describe	VBN
cord-015935-r2wd1yfa	153	16	below	below	RB
cord-015935-r2wd1yfa	153	17	,	,	,
cord-015935-r2wd1yfa	153	18	could	could	MD
cord-015935-r2wd1yfa	153	19	contribute	contribute	VB
cord-015935-r2wd1yfa	153	20	to	to	IN
cord-015935-r2wd1yfa	153	21	this	this	DT
cord-015935-r2wd1yfa	153	22	large	large	JJ
cord-015935-r2wd1yfa	153	23	MZ	MZ	NNP
cord-015935-r2wd1yfa	153	24	/	/	SYM
cord-015935-r2wd1yfa	153	25	DZ	DZ	NNP
cord-015935-r2wd1yfa	153	26	discordance	discordance	NN
cord-015935-r2wd1yfa	153	27	.	.	.
cord-015935-r2wd1yfa	154	1	Individuals	individual	NNS
cord-015935-r2wd1yfa	154	2	with	with	IN
cord-015935-r2wd1yfa	154	3	autism	autism	NN
cord-015935-r2wd1yfa	154	4	rarely	rarely	RB
cord-015935-r2wd1yfa	154	5	marry	marry	VBP
cord-015935-r2wd1yfa	154	6	and	and	CC
cord-015935-r2wd1yfa	154	7	have	have	VB
cord-015935-r2wd1yfa	154	8	children	child	NNS
cord-015935-r2wd1yfa	154	9	so	so	IN
cord-015935-r2wd1yfa	154	10	that	that	IN
cord-015935-r2wd1yfa	154	11	vertical	vertical	JJ
cord-015935-r2wd1yfa	154	12	transmission	transmission	NN
cord-015935-r2wd1yfa	154	13	of	of	IN
cord-015935-r2wd1yfa	154	14	the	the	DT
cord-015935-r2wd1yfa	154	15	diagnosis	diagnosis	NN
cord-015935-r2wd1yfa	154	16	from	from	IN
cord-015935-r2wd1yfa	154	17	parent	parent	NN
cord-015935-r2wd1yfa	154	18	to	to	IN
cord-015935-r2wd1yfa	154	19	child	child	NN
cord-015935-r2wd1yfa	154	20	is	be	VBZ
cord-015935-r2wd1yfa	154	21	rarely	rarely	RB
cord-015935-r2wd1yfa	154	22	observed	observe	VBN
cord-015935-r2wd1yfa	154	23	(	(	-LRB-
cord-015935-r2wd1yfa	154	24	Pennington	Pennington	NNP
cord-015935-r2wd1yfa	154	25	,	,	,
cord-015935-r2wd1yfa	154	26	2009	2009	CD
cord-015935-r2wd1yfa	154	27	)	)	-RRB-
cord-015935-r2wd1yfa	154	28	.	.	.
cord-015935-r2wd1yfa	155	1	However	however	RB
cord-015935-r2wd1yfa	155	2	,	,	,
cord-015935-r2wd1yfa	155	3	genetic	genetic	JJ
cord-015935-r2wd1yfa	155	4	transmission	transmission	NN
cord-015935-r2wd1yfa	155	5	is	be	VBZ
cord-015935-r2wd1yfa	155	6	still	still	RB
cord-015935-r2wd1yfa	155	7	possible	possible	JJ
cord-015935-r2wd1yfa	155	8	as	as	IN
cord-015935-r2wd1yfa	155	9	parents	parent	NNS
cord-015935-r2wd1yfa	155	10	can	can	MD
cord-015935-r2wd1yfa	155	11	transmit	transmit	VB
cord-015935-r2wd1yfa	155	12	genetic	genetic	JJ
cord-015935-r2wd1yfa	155	13	risk	risk	NN
cord-015935-r2wd1yfa	155	14	factors	factor	NNS
cord-015935-r2wd1yfa	155	15	without	without	IN
cord-015935-r2wd1yfa	155	16	having	have	VBG
cord-015935-r2wd1yfa	155	17	the	the	DT
cord-015935-r2wd1yfa	155	18	diagnosis	diagnosis	NN
cord-015935-r2wd1yfa	155	19	themselves	-PRON-	PRP
cord-015935-r2wd1yfa	155	20	.	.	.
cord-015935-r2wd1yfa	156	1	Family	family	NN
cord-015935-r2wd1yfa	156	2	studies	study	NNS
cord-015935-r2wd1yfa	156	3	(	(	-LRB-
cord-015935-r2wd1yfa	156	4	cited	cite	VBN
cord-015935-r2wd1yfa	156	5	in	in	IN
cord-015935-r2wd1yfa	156	6	Geschwind	Geschwind	NNP
cord-015935-r2wd1yfa	156	7	&	&	CC
cord-015935-r2wd1yfa	156	8	Konopka	Konopka	NNP
cord-015935-r2wd1yfa	156	9	,	,	,
cord-015935-r2wd1yfa	156	10	2009	2009	CD
cord-015935-r2wd1yfa	156	11	;	;	:
cord-015935-r2wd1yfa	156	12	Pennington	Pennington	NNP
cord-015935-r2wd1yfa	156	13	,	,	,
cord-015935-r2wd1yfa	156	14	2009	2009	CD
cord-015935-r2wd1yfa	156	15	)	)	-RRB-
cord-015935-r2wd1yfa	156	16	suggest	suggest	VBP
cord-015935-r2wd1yfa	156	17	that	that	IN
cord-015935-r2wd1yfa	156	18	the	the	DT
cord-015935-r2wd1yfa	156	19	risk	risk	NN
cord-015935-r2wd1yfa	156	20	of	of	IN
cord-015935-r2wd1yfa	156	21	autism	autism	NN
cord-015935-r2wd1yfa	156	22	is	be	VBZ
cord-015935-r2wd1yfa	156	23	20	20	CD
cord-015935-r2wd1yfa	156	24	-	-	SYM
cord-015935-r2wd1yfa	156	25	60	60	CD
cord-015935-r2wd1yfa	156	26	%	%	NN
cord-015935-r2wd1yfa	156	27	higher	high	JJR
cord-015935-r2wd1yfa	156	28	in	in	IN
cord-015935-r2wd1yfa	156	29	siblings	sibling	NNS
cord-015935-r2wd1yfa	156	30	compared	compare	VBN
cord-015935-r2wd1yfa	156	31	to	to	IN
cord-015935-r2wd1yfa	156	32	the	the	DT
cord-015935-r2wd1yfa	156	33	incidence	incidence	NN
cord-015935-r2wd1yfa	156	34	of	of	IN
cord-015935-r2wd1yfa	156	35	autism	autism	NN
cord-015935-r2wd1yfa	156	36	in	in	IN
cord-015935-r2wd1yfa	156	37	the	the	DT
cord-015935-r2wd1yfa	156	38	general	general	JJ
cord-015935-r2wd1yfa	156	39	population	population	NN
cord-015935-r2wd1yfa	156	40	,	,	,
cord-015935-r2wd1yfa	156	41	and	and	CC
cord-015935-r2wd1yfa	156	42	to	to	IN
cord-015935-r2wd1yfa	156	43	that	that	DT
cord-015935-r2wd1yfa	156	44	of	of	IN
cord-015935-r2wd1yfa	156	45	other	other	JJ
cord-015935-r2wd1yfa	156	46	psychiatric	psychiatric	JJ
cord-015935-r2wd1yfa	156	47	disorders	disorder	NNS
cord-015935-r2wd1yfa	156	48	.	.	.
cord-015935-r2wd1yfa	157	1	Several	several	JJ
cord-015935-r2wd1yfa	157	2	studies	study	NNS
cord-015935-r2wd1yfa	157	3	have	have	VBP
cord-015935-r2wd1yfa	157	4	shown	show	VBN
cord-015935-r2wd1yfa	157	5	that	that	IN
cord-015935-r2wd1yfa	157	6	a	a	DT
cord-015935-r2wd1yfa	157	7	broad	broad	JJ
cord-015935-r2wd1yfa	157	8	autism	autism	NN
cord-015935-r2wd1yfa	157	9	phenotype	phenotype	NN
cord-015935-r2wd1yfa	157	10	is	be	VBZ
cord-015935-r2wd1yfa	157	11	transmitted	transmit	VBN
cord-015935-r2wd1yfa	157	12	in	in	IN
cord-015935-r2wd1yfa	157	13	families	family	NNS
cord-015935-r2wd1yfa	157	14	of	of	IN
cord-015935-r2wd1yfa	157	15	individuals	individual	NNS
cord-015935-r2wd1yfa	157	16	with	with	IN
cord-015935-r2wd1yfa	157	17	autism	autism	NN
cord-015935-r2wd1yfa	157	18	(	(	-LRB-
cord-015935-r2wd1yfa	157	19	Piven	Piven	NNP
cord-015935-r2wd1yfa	157	20	,	,	,
cord-015935-r2wd1yfa	157	21	1999	1999	CD
cord-015935-r2wd1yfa	157	22	;	;	:
cord-015935-r2wd1yfa	157	23	Rutter	Rutter	NNP
cord-015935-r2wd1yfa	157	24	,	,	,
cord-015935-r2wd1yfa	157	25	2000	2000	CD
cord-015935-r2wd1yfa	157	26	)	)	-RRB-
cord-015935-r2wd1yfa	157	27	.	.	.
cord-015935-r2wd1yfa	158	1	For	for	IN
cord-015935-r2wd1yfa	158	2	example	example	NN
cord-015935-r2wd1yfa	158	3	,	,	,
cord-015935-r2wd1yfa	158	4	first	first	JJ
cord-015935-r2wd1yfa	158	5	-	-	HYPH
cord-015935-r2wd1yfa	158	6	degree	degree	NN
cord-015935-r2wd1yfa	158	7	relatives	relative	NNS
cord-015935-r2wd1yfa	158	8	of	of	IN
cord-015935-r2wd1yfa	158	9	individuals	individual	NNS
cord-015935-r2wd1yfa	158	10	with	with	IN
cord-015935-r2wd1yfa	158	11	autism	autism	NN
cord-015935-r2wd1yfa	158	12	were	be	VBD
cord-015935-r2wd1yfa	158	13	shown	show	VBN
cord-015935-r2wd1yfa	158	14	to	to	TO
cord-015935-r2wd1yfa	158	15	be	be	VB
cord-015935-r2wd1yfa	158	16	shy	shy	JJ
cord-015935-r2wd1yfa	158	17	,	,	,
cord-015935-r2wd1yfa	158	18	aloof	aloof	JJ
cord-015935-r2wd1yfa	158	19	,	,	,
cord-015935-r2wd1yfa	158	20	and	and	CC
cord-015935-r2wd1yfa	158	21	have	have	VBP
cord-015935-r2wd1yfa	158	22	problematic	problematic	JJ
cord-015935-r2wd1yfa	158	23	pragmatic	pragmatic	JJ
cord-015935-r2wd1yfa	158	24	language	language	NN
cord-015935-r2wd1yfa	158	25	(	(	-LRB-
cord-015935-r2wd1yfa	158	26	Rutter	Rutter	NNP
cord-015935-r2wd1yfa	158	27	,	,	,
cord-015935-r2wd1yfa	158	28	2000	2000	CD
cord-015935-r2wd1yfa	158	29	)	)	-RRB-
cord-015935-r2wd1yfa	158	30	.	.	.
cord-015935-r2wd1yfa	159	1	This	this	DT
cord-015935-r2wd1yfa	159	2	pattern	pattern	NN
cord-015935-r2wd1yfa	159	3	is	be	VBZ
cord-015935-r2wd1yfa	159	4	consistent	consistent	JJ
cord-015935-r2wd1yfa	159	5	with	with	IN
cord-015935-r2wd1yfa	159	6	the	the	DT
cord-015935-r2wd1yfa	159	7	segregation	segregation	NN
cord-015935-r2wd1yfa	159	8	of	of	IN
cord-015935-r2wd1yfa	159	9	sub	sub	NN
cord-015935-r2wd1yfa	159	10	-	-	JJ
cord-015935-r2wd1yfa	159	11	threshold	threshold	JJ
cord-015935-r2wd1yfa	159	12	traits	trait	NNS
cord-015935-r2wd1yfa	159	13	within	within	IN
cord-015935-r2wd1yfa	159	14	these	these	DT
cord-015935-r2wd1yfa	159	15	families	family	NNS
cord-015935-r2wd1yfa	159	16	(	(	-LRB-
cord-015935-r2wd1yfa	159	17	Abrahams	Abrahams	NNP
cord-015935-r2wd1yfa	159	18	&	&	CC
cord-015935-r2wd1yfa	159	19	Geschwind	Geschwind	NNP
cord-015935-r2wd1yfa	159	20	,	,	,
cord-015935-r2wd1yfa	159	21	2008	2008	CD
cord-015935-r2wd1yfa	159	22	)	)	-RRB-
cord-015935-r2wd1yfa	159	23	.	.	.
cord-015935-r2wd1yfa	160	1	Finally	finally	RB
cord-015935-r2wd1yfa	160	2	,	,	,
cord-015935-r2wd1yfa	160	3	autism	autism	NN
cord-015935-r2wd1yfa	160	4	affects	affect	VBZ
cord-015935-r2wd1yfa	160	5	more	more	JJR
cord-015935-r2wd1yfa	160	6	boys	boy	NNS
cord-015935-r2wd1yfa	160	7	than	than	IN
cord-015935-r2wd1yfa	160	8	girls	girl	NNS
cord-015935-r2wd1yfa	160	9	(	(	-LRB-
cord-015935-r2wd1yfa	160	10	4:1	4:1	CD
cord-015935-r2wd1yfa	160	11	)	)	-RRB-
cord-015935-r2wd1yfa	160	12	,	,	,
cord-015935-r2wd1yfa	160	13	a	a	DT
cord-015935-r2wd1yfa	160	14	finding	finding	NN
cord-015935-r2wd1yfa	160	15	which	which	WDT
cord-015935-r2wd1yfa	160	16	has	have	VBZ
cord-015935-r2wd1yfa	160	17	remained	remain	VBN
cord-015935-r2wd1yfa	160	18	constant	constant	JJ
cord-015935-r2wd1yfa	160	19	since	since	IN
cord-015935-r2wd1yfa	160	20	Kanner	Kanner	NNP
cord-015935-r2wd1yfa	160	21	's	's	POS
cord-015935-r2wd1yfa	160	22	first	first	JJ
cord-015935-r2wd1yfa	160	23	description	description	NN
cord-015935-r2wd1yfa	160	24	of	of	IN
cord-015935-r2wd1yfa	160	25	autism	autism	NN
cord-015935-r2wd1yfa	160	26	in	in	IN
cord-015935-r2wd1yfa	160	27	1945	1945	CD
cord-015935-r2wd1yfa	160	28	,	,	,
cord-015935-r2wd1yfa	160	29	and	and	CC
cord-015935-r2wd1yfa	160	30	despite	despite	IN
cord-015935-r2wd1yfa	160	31	the	the	DT
cord-015935-r2wd1yfa	160	32	increasing	increase	VBG
cord-015935-r2wd1yfa	160	33	incidence	incidence	NN
cord-015935-r2wd1yfa	160	34	of	of	IN
cord-015935-r2wd1yfa	160	35	this	this	DT
cord-015935-r2wd1yfa	160	36	diagnosis	diagnosis	NN
cord-015935-r2wd1yfa	160	37	.	.	.
cord-015935-r2wd1yfa	161	1	The	the	DT
cord-015935-r2wd1yfa	161	2	predominantly	predominantly	RB
cord-015935-r2wd1yfa	161	3	male	male	JJ
cord-015935-r2wd1yfa	161	4	ratio	ratio	NN
cord-015935-r2wd1yfa	161	5	has	have	VBZ
cord-015935-r2wd1yfa	161	6	been	be	VBN
cord-015935-r2wd1yfa	161	7	attributed	attribute	VBN
cord-015935-r2wd1yfa	161	8	to	to	IN
cord-015935-r2wd1yfa	161	9	an	an	DT
cord-015935-r2wd1yfa	161	10	abnormality	abnormality	NN
cord-015935-r2wd1yfa	161	11	on	on	IN
cord-015935-r2wd1yfa	161	12	the	the	DT
cord-015935-r2wd1yfa	161	13	X	x	NN
cord-015935-r2wd1yfa	161	14	chromosome	chromosome	NN
cord-015935-r2wd1yfa	161	15	(	(	-LRB-
cord-015935-r2wd1yfa	161	16	discussed	discuss	VBN
cord-015935-r2wd1yfa	161	17	below	below	IN
cord-015935-r2wd1yfa	161	18	)	)	-RRB-
cord-015935-r2wd1yfa	161	19	,	,	,
cord-015935-r2wd1yfa	161	20	or	or	CC
cord-015935-r2wd1yfa	161	21	to	to	TO
cord-015935-r2wd1yfa	161	22	sex	sex	NN
cord-015935-r2wd1yfa	161	23	linkage	linkage	NN
cord-015935-r2wd1yfa	161	24	or	or	CC
cord-015935-r2wd1yfa	161	25	genomic	genomic	JJ
cord-015935-r2wd1yfa	161	26	imprinting	imprinting	NN
cord-015935-r2wd1yfa	161	27	(	(	-LRB-
cord-015935-r2wd1yfa	161	28	Lintas	Lintas	NNP
cord-015935-r2wd1yfa	161	29	&	&	CC
cord-015935-r2wd1yfa	161	30	Persico	Persico	NNP
cord-015935-r2wd1yfa	161	31	,	,	,
cord-015935-r2wd1yfa	161	32	2009	2009	CD
cord-015935-r2wd1yfa	161	33	;	;	:
cord-015935-r2wd1yfa	161	34	Marco	Marco	NNP
cord-015935-r2wd1yfa	161	35	&	&	CC
cord-015935-r2wd1yfa	161	36	Skuse	Skuse	NNP
cord-015935-r2wd1yfa	161	37	,	,	,
cord-015935-r2wd1yfa	161	38	2006	2006	CD
cord-015935-r2wd1yfa	161	39	)	)	-RRB-
cord-015935-r2wd1yfa	161	40	.	.	.
cord-015935-r2wd1yfa	162	1	Sex	sex	NN
cord-015935-r2wd1yfa	162	2	linkage	linkage	NN
cord-015935-r2wd1yfa	162	3	involves	involve	VBZ
cord-015935-r2wd1yfa	162	4	a	a	DT
cord-015935-r2wd1yfa	162	5	gene	gene	NN
cord-015935-r2wd1yfa	162	6	on	on	IN
cord-015935-r2wd1yfa	162	7	the	the	DT
cord-015935-r2wd1yfa	162	8	X	x	NN
cord-015935-r2wd1yfa	162	9	chromosome	chromosome	NN
cord-015935-r2wd1yfa	162	10	transmitted	transmit	VBN
cord-015935-r2wd1yfa	162	11	from	from	IN
cord-015935-r2wd1yfa	162	12	the	the	DT
cord-015935-r2wd1yfa	162	13	mother	mother	NN
cord-015935-r2wd1yfa	162	14	to	to	IN
cord-015935-r2wd1yfa	162	15	the	the	DT
cord-015935-r2wd1yfa	162	16	son	son	NN
cord-015935-r2wd1yfa	162	17	.	.	.
cord-015935-r2wd1yfa	163	1	As	as	IN
cord-015935-r2wd1yfa	163	2	the	the	DT
cord-015935-r2wd1yfa	163	3	son	son	NN
cord-015935-r2wd1yfa	163	4	has	have	VBZ
cord-015935-r2wd1yfa	163	5	only	only	RB
cord-015935-r2wd1yfa	163	6	one	one	CD
cord-015935-r2wd1yfa	163	7	X	x	NN
cord-015935-r2wd1yfa	163	8	chromosome	chromosome	NN
cord-015935-r2wd1yfa	163	9	,	,	,
cord-015935-r2wd1yfa	163	10	this	this	DT
cord-015935-r2wd1yfa	163	11	gene	gene	NN
cord-015935-r2wd1yfa	163	12	would	would	MD
cord-015935-r2wd1yfa	163	13	be	be	VB
cord-015935-r2wd1yfa	163	14	expressed	express	VBN
cord-015935-r2wd1yfa	163	15	.	.	.
cord-015935-r2wd1yfa	164	1	Since	since	IN
cord-015935-r2wd1yfa	164	2	the	the	DT
cord-015935-r2wd1yfa	164	3	mother	mother	NN
cord-015935-r2wd1yfa	164	4	's	's	POS
cord-015935-r2wd1yfa	164	5	daughter	daughter	NN
cord-015935-r2wd1yfa	164	6	has	have	VBZ
cord-015935-r2wd1yfa	164	7	two	two	CD
cord-015935-r2wd1yfa	164	8	copies	copy	NNS
cord-015935-r2wd1yfa	164	9	of	of	IN
cord-015935-r2wd1yfa	164	10	the	the	DT
cord-015935-r2wd1yfa	164	11	X	x	NN
cord-015935-r2wd1yfa	164	12	chromosome	chromosome	NN
cord-015935-r2wd1yfa	164	13	-one	-one	CD
cord-015935-r2wd1yfa	164	14	from	from	IN
cord-015935-r2wd1yfa	164	15	her	-PRON-	PRP$
cord-015935-r2wd1yfa	164	16	father	father	NN
cord-015935-r2wd1yfa	164	17	and	and	CC
cord-015935-r2wd1yfa	164	18	one	one	CD
cord-015935-r2wd1yfa	164	19	from	from	IN
cord-015935-r2wd1yfa	164	20	her	-PRON-	PRP$
cord-015935-r2wd1yfa	164	21	mother	mother	NN
cord-015935-r2wd1yfa	164	22	-the	-the	DT
cord-015935-r2wd1yfa	164	23	daughter	daughter	NN
cord-015935-r2wd1yfa	165	1	likely	likely	RB
cord-015935-r2wd1yfa	165	2	would	would	MD
cord-015935-r2wd1yfa	165	3	not	not	RB
cord-015935-r2wd1yfa	165	4	express	express	VB
cord-015935-r2wd1yfa	165	5	the	the	DT
cord-015935-r2wd1yfa	165	6	abnormal	abnormal	JJ
cord-015935-r2wd1yfa	165	7	phenotype	phenotype	NN
cord-015935-r2wd1yfa	165	8	.	.	.
cord-015935-r2wd1yfa	166	1	The	the	DT
cord-015935-r2wd1yfa	166	2	most	most	RBS
cord-015935-r2wd1yfa	166	3	well	well	RB
cord-015935-r2wd1yfa	166	4	-	-	HYPH
cord-015935-r2wd1yfa	166	5	known	know	VBN
cord-015935-r2wd1yfa	166	6	example	example	NN
cord-015935-r2wd1yfa	166	7	of	of	IN
cord-015935-r2wd1yfa	166	8	a	a	DT
cord-015935-r2wd1yfa	166	9	sex	sex	NN
cord-015935-r2wd1yfa	166	10	-	-	HYPH
cord-015935-r2wd1yfa	166	11	linked	link	VBN
cord-015935-r2wd1yfa	166	12	disorder	disorder	NN
cord-015935-r2wd1yfa	166	13	is	be	VBZ
cord-015935-r2wd1yfa	166	14	hemophilia	hemophilia	NN
cord-015935-r2wd1yfa	166	15	,	,	,
cord-015935-r2wd1yfa	166	16	which	which	WDT
cord-015935-r2wd1yfa	166	17	is	be	VBZ
cord-015935-r2wd1yfa	166	18	on	on	IN
cord-015935-r2wd1yfa	166	19	the	the	DT
cord-015935-r2wd1yfa	166	20	X	x	NN
cord-015935-r2wd1yfa	166	21	chromosome	chromosome	NN
cord-015935-r2wd1yfa	166	22	.	.	.
cord-015935-r2wd1yfa	167	1	Genomic	genomic	JJ
cord-015935-r2wd1yfa	167	2	imprinting	imprinting	NN
cord-015935-r2wd1yfa	167	3	,	,	,
cord-015935-r2wd1yfa	167	4	on	on	IN
cord-015935-r2wd1yfa	167	5	the	the	DT
cord-015935-r2wd1yfa	167	6	other	other	JJ
cord-015935-r2wd1yfa	167	7	hand	hand	NN
cord-015935-r2wd1yfa	167	8	,	,	,
cord-015935-r2wd1yfa	167	9	is	be	VBZ
cord-015935-r2wd1yfa	167	10	an	an	DT
cord-015935-r2wd1yfa	167	11	epigenetic	epigenetic	JJ
cord-015935-r2wd1yfa	167	12	phenomenon	phenomenon	NN
cord-015935-r2wd1yfa	167	13	wherein	wherein	WRB
cord-015935-r2wd1yfa	167	14	chemical	chemical	JJ
cord-015935-r2wd1yfa	167	15	modification	modification	NN
cord-015935-r2wd1yfa	167	16	of	of	IN
cord-015935-r2wd1yfa	167	17	DNA	dna	NN
cord-015935-r2wd1yfa	167	18	that	that	WDT
cord-015935-r2wd1yfa	167	19	does	do	VBZ
cord-015935-r2wd1yfa	167	20	not	not	RB
cord-015935-r2wd1yfa	167	21	alter	alter	VB
cord-015935-r2wd1yfa	167	22	the	the	DT
cord-015935-r2wd1yfa	167	23	basic	basic	JJ
cord-015935-r2wd1yfa	167	24	DNA	dna	NN
cord-015935-r2wd1yfa	167	25	sequence	sequence	NN
cord-015935-r2wd1yfa	167	26	or	or	CC
cord-015935-r2wd1yfa	167	27	modification	modification	NN
cord-015935-r2wd1yfa	167	28	of	of	IN
cord-015935-r2wd1yfa	167	29	the	the	DT
cord-015935-r2wd1yfa	167	30	DNA	dna	NN
cord-015935-r2wd1yfa	167	31	-	-	HYPH
cord-015935-r2wd1yfa	167	32	associated	associate	VBN
cord-015935-r2wd1yfa	167	33	histone	histone	NN
cord-015935-r2wd1yfa	167	34	proteins	protein	NNS
cord-015935-r2wd1yfa	167	35	determines	determine	VBZ
cord-015935-r2wd1yfa	167	36	whether	whether	IN
cord-015935-r2wd1yfa	167	37	the	the	DT
cord-015935-r2wd1yfa	167	38	maternal	maternal	JJ
cord-015935-r2wd1yfa	167	39	or	or	CC
cord-015935-r2wd1yfa	167	40	the	the	DT
cord-015935-r2wd1yfa	167	41	paternal	paternal	JJ
cord-015935-r2wd1yfa	167	42	copy	copy	NN
cord-015935-r2wd1yfa	167	43	of	of	IN
cord-015935-r2wd1yfa	167	44	a	a	DT
cord-015935-r2wd1yfa	167	45	specific	specific	JJ
cord-015935-r2wd1yfa	167	46	gene	gene	NN
cord-015935-r2wd1yfa	167	47	is	be	VBZ
cord-015935-r2wd1yfa	167	48	expressed	express	VBN
cord-015935-r2wd1yfa	167	49	.	.	.
cord-015935-r2wd1yfa	168	1	Genomic	genomic	JJ
cord-015935-r2wd1yfa	168	2	imprinting	imprinting	NN
cord-015935-r2wd1yfa	168	3	has	have	VBZ
cord-015935-r2wd1yfa	168	4	been	be	VBN
cord-015935-r2wd1yfa	168	5	determined	determine	VBN
cord-015935-r2wd1yfa	168	6	for	for	IN
cord-015935-r2wd1yfa	168	7	Prader	Prader	NNP
cord-015935-r2wd1yfa	168	8	Willi	Willi	NNP
cord-015935-r2wd1yfa	168	9	and	and	CC
cord-015935-r2wd1yfa	168	10	Angelman	Angelman	NNP
cord-015935-r2wd1yfa	168	11	's	's	POS
cord-015935-r2wd1yfa	168	12	syndrome	syndrome	NN
cord-015935-r2wd1yfa	168	13	.	.	.
cord-015935-r2wd1yfa	169	1	Finally	finally	RB
cord-015935-r2wd1yfa	169	2	,	,	,
cord-015935-r2wd1yfa	169	3	increased	increase	VBN
cord-015935-r2wd1yfa	169	4	risk	risk	NN
cord-015935-r2wd1yfa	169	5	for	for	IN
cord-015935-r2wd1yfa	169	6	autism	autism	NN
cord-015935-r2wd1yfa	169	7	has	have	VBZ
cord-015935-r2wd1yfa	169	8	been	be	VBN
cord-015935-r2wd1yfa	169	9	identified	identify	VBN
cord-015935-r2wd1yfa	169	10	in	in	IN
cord-015935-r2wd1yfa	169	11	the	the	DT
cord-015935-r2wd1yfa	169	12	offspring	offspring	NN
cord-015935-r2wd1yfa	169	13	of	of	IN
cord-015935-r2wd1yfa	169	14	older	old	JJR
cord-015935-r2wd1yfa	169	15	fathers	father	NNS
cord-015935-r2wd1yfa	169	16	(	(	-LRB-
cord-015935-r2wd1yfa	169	17	Reichenberg	Reichenberg	NNP
cord-015935-r2wd1yfa	169	18	et	et	NNP
cord-015935-r2wd1yfa	169	19	al	al	NNP
cord-015935-r2wd1yfa	169	20	.	.	NNP
cord-015935-r2wd1yfa	169	21	,	,	,
cord-015935-r2wd1yfa	169	22	2006	2006	CD
cord-015935-r2wd1yfa	169	23	)	)	-RRB-
cord-015935-r2wd1yfa	169	24	.	.	.
cord-015935-r2wd1yfa	170	1	Therefore	therefore	RB
cord-015935-r2wd1yfa	170	2	,	,	,
cord-015935-r2wd1yfa	170	3	the	the	DT
cord-015935-r2wd1yfa	170	4	gender	gender	NN
cord-015935-r2wd1yfa	170	5	and	and	CC
cord-015935-r2wd1yfa	170	6	age	age	NN
cord-015935-r2wd1yfa	170	7	of	of	IN
cord-015935-r2wd1yfa	170	8	the	the	DT
cord-015935-r2wd1yfa	170	9	parent	parent	NN
cord-015935-r2wd1yfa	170	10	may	may	MD
cord-015935-r2wd1yfa	170	11	confer	confer	VB
cord-015935-r2wd1yfa	170	12	risk	risk	NN
cord-015935-r2wd1yfa	170	13	for	for	IN
cord-015935-r2wd1yfa	170	14	offspring	offspring	NN
cord-015935-r2wd1yfa	170	15	with	with	IN
cord-015935-r2wd1yfa	170	16	autism	autism	NN
cord-015935-r2wd1yfa	170	17	.	.	.
cord-015935-r2wd1yfa	171	1	The	the	DT
cord-015935-r2wd1yfa	171	2	conclusion	conclusion	NN
cord-015935-r2wd1yfa	171	3	drawn	draw	VBN
cord-015935-r2wd1yfa	171	4	from	from	IN
cord-015935-r2wd1yfa	171	5	indirect	indirect	JJ
cord-015935-r2wd1yfa	171	6	evidence	evidence	NN
cord-015935-r2wd1yfa	171	7	is	be	VBZ
cord-015935-r2wd1yfa	171	8	that	that	IN
cord-015935-r2wd1yfa	171	9	autism	autism	NN
cord-015935-r2wd1yfa	171	10	is	be	VBZ
cord-015935-r2wd1yfa	171	11	the	the	DT
cord-015935-r2wd1yfa	171	12	most	most	RBS
cord-015935-r2wd1yfa	171	13	heritable	heritable	JJ
cord-015935-r2wd1yfa	171	14	and	and	CC
cord-015935-r2wd1yfa	171	15	familial	familial	JJ
cord-015935-r2wd1yfa	171	16	neurodevelopmental	neurodevelopmental	JJ
cord-015935-r2wd1yfa	171	17	disorder	disorder	NN
cord-015935-r2wd1yfa	171	18	(	(	-LRB-
cord-015935-r2wd1yfa	171	19	Pennington	Pennington	NNP
cord-015935-r2wd1yfa	171	20	,	,	,
cord-015935-r2wd1yfa	171	21	2009	2009	CD
cord-015935-r2wd1yfa	171	22	)	)	-RRB-
cord-015935-r2wd1yfa	171	23	.	.	.
cord-015935-r2wd1yfa	172	1	With	with	IN
cord-015935-r2wd1yfa	172	2	rare	rare	JJ
cord-015935-r2wd1yfa	172	3	exceptions	exception	NNS
cord-015935-r2wd1yfa	172	4	,	,	,
cord-015935-r2wd1yfa	172	5	however	however	RB
cord-015935-r2wd1yfa	172	6	,	,	,
cord-015935-r2wd1yfa	172	7	autism	autism	NN
cord-015935-r2wd1yfa	172	8	does	do	VBZ
cord-015935-r2wd1yfa	172	9	not	not	RB
cord-015935-r2wd1yfa	172	10	appear	appear	VB
cord-015935-r2wd1yfa	172	11	to	to	TO
cord-015935-r2wd1yfa	172	12	be	be	VB
cord-015935-r2wd1yfa	172	13	the	the	DT
cord-015935-r2wd1yfa	172	14	action	action	NN
cord-015935-r2wd1yfa	172	15	of	of	IN
cord-015935-r2wd1yfa	172	16	a	a	DT
cord-015935-r2wd1yfa	172	17	single	single	JJ
cord-015935-r2wd1yfa	172	18	gene	gene	NN
cord-015935-r2wd1yfa	172	19	inherited	inherit	VBN
cord-015935-r2wd1yfa	172	20	in	in	IN
cord-015935-r2wd1yfa	172	21	a	a	DT
cord-015935-r2wd1yfa	172	22	strictly	strictly	RB
cord-015935-r2wd1yfa	172	23	Mendelian	mendelian	JJ
cord-015935-r2wd1yfa	172	24	pattern	pattern	NN
cord-015935-r2wd1yfa	172	25	(	(	-LRB-
cord-015935-r2wd1yfa	172	26	autosomal	autosomal	JJ
cord-015935-r2wd1yfa	172	27	dominant	dominant	JJ
cord-015935-r2wd1yfa	172	28	,	,	,
cord-015935-r2wd1yfa	172	29	recessive	recessive	JJ
cord-015935-r2wd1yfa	172	30	,	,	,
cord-015935-r2wd1yfa	172	31	or	or	CC
cord-015935-r2wd1yfa	172	32	X	X	NNS
cord-015935-r2wd1yfa	172	33	-	-	HYPH
cord-015935-r2wd1yfa	172	34	linked	link	VBN
cord-015935-r2wd1yfa	172	35	;	;	:
cord-015935-r2wd1yfa	172	36	Gupta	Gupta	NNP
cord-015935-r2wd1yfa	172	37	&	&	CC
cord-015935-r2wd1yfa	172	38	State	State	NNP
cord-015935-r2wd1yfa	172	39	,	,	,
cord-015935-r2wd1yfa	172	40	2007	2007	CD
cord-015935-r2wd1yfa	172	41	;	;	:
cord-015935-r2wd1yfa	172	42	O'Roak	O'Roak	NNP
cord-015935-r2wd1yfa	172	43	&	&	CC
cord-015935-r2wd1yfa	172	44	State	State	NNP
cord-015935-r2wd1yfa	172	45	,	,	,
cord-015935-r2wd1yfa	172	46	2008	2008	CD
cord-015935-r2wd1yfa	172	47	)	)	-RRB-
cord-015935-r2wd1yfa	172	48	.	.	.
cord-015935-r2wd1yfa	173	1	Rather	rather	RB
cord-015935-r2wd1yfa	173	2	,	,	,
cord-015935-r2wd1yfa	173	3	there	there	EX
cord-015935-r2wd1yfa	173	4	are	be	VBP
cord-015935-r2wd1yfa	173	5	reports	report	NNS
cord-015935-r2wd1yfa	173	6	of	of	IN
cord-015935-r2wd1yfa	173	7	multiple	multiple	JJ
cord-015935-r2wd1yfa	173	8	,	,	,
cord-015935-r2wd1yfa	173	9	distinctly	distinctly	RB
cord-015935-r2wd1yfa	173	10	rare	rare	JJ
cord-015935-r2wd1yfa	173	11	changes	change	NNS
cord-015935-r2wd1yfa	173	12	in	in	IN
cord-015935-r2wd1yfa	173	13	the	the	DT
cord-015935-r2wd1yfa	173	14	genetic	genetic	JJ
cord-015935-r2wd1yfa	173	15	code	code	NN
cord-015935-r2wd1yfa	173	16	in	in	IN
cord-015935-r2wd1yfa	173	17	small	small	JJ
cord-015935-r2wd1yfa	173	18	subsets	subset	NNS
cord-015935-r2wd1yfa	173	19	of	of	IN
cord-015935-r2wd1yfa	173	20	individuals	individual	NNS
cord-015935-r2wd1yfa	173	21	that	that	WDT
cord-015935-r2wd1yfa	173	22	cause	cause	VBP
cord-015935-r2wd1yfa	173	23	or	or	CC
cord-015935-r2wd1yfa	173	24	contribute	contribute	VBP
cord-015935-r2wd1yfa	173	25	to	to	IN
cord-015935-r2wd1yfa	173	26	autism	autism	NN
cord-015935-r2wd1yfa	173	27	.	.	.
cord-015935-r2wd1yfa	174	1	There	there	EX
cord-015935-r2wd1yfa	174	2	may	may	MD
cord-015935-r2wd1yfa	174	3	be	be	VB
cord-015935-r2wd1yfa	174	4	multiple	multiple	JJ
cord-015935-r2wd1yfa	174	5	gene	gene	NN
cord-015935-r2wd1yfa	174	6	variants	variant	NNS
cord-015935-r2wd1yfa	175	1	-"a	-"a	NNP
cord-015935-r2wd1yfa	176	1	conspiracy	conspiracy	NN
cord-015935-r2wd1yfa	176	2	of	of	IN
cord-015935-r2wd1yfa	176	3	multiple	multiple	JJ
cord-015935-r2wd1yfa	176	4	genes	gene	NNS
cord-015935-r2wd1yfa	176	5	"	"	''
cord-015935-r2wd1yfa	176	6	(	(	-LRB-
cord-015935-r2wd1yfa	176	7	Gupta	Gupta	NNP
cord-015935-r2wd1yfa	176	8	&	&	CC
cord-015935-r2wd1yfa	176	9	State	State	NNP
cord-015935-r2wd1yfa	176	10	,	,	,
cord-015935-r2wd1yfa	176	11	2007	2007	CD
cord-015935-r2wd1yfa	176	12	)	)	-RRB-
cord-015935-r2wd1yfa	177	1	-that	-that	WDT
cord-015935-r2wd1yfa	177	2	converge	converge	VBP
cord-015935-r2wd1yfa	177	3	leading	lead	VBG
cord-015935-r2wd1yfa	177	4	to	to	IN
cord-015935-r2wd1yfa	177	5	a	a	DT
cord-015935-r2wd1yfa	177	6	given	give	VBN
cord-015935-r2wd1yfa	177	7	phenotype	phenotype	NN
cord-015935-r2wd1yfa	177	8	.	.	.
cord-015935-r2wd1yfa	178	1	Despite	despite	IN
cord-015935-r2wd1yfa	178	2	the	the	DT
cord-015935-r2wd1yfa	178	3	indirect	indirect	JJ
cord-015935-r2wd1yfa	178	4	evidence	evidence	NN
cord-015935-r2wd1yfa	178	5	for	for	IN
cord-015935-r2wd1yfa	178	6	heritability	heritability	NN
cord-015935-r2wd1yfa	178	7	and	and	CC
cord-015935-r2wd1yfa	178	8	recent	recent	JJ
cord-015935-r2wd1yfa	178	9	genetic	genetic	JJ
cord-015935-r2wd1yfa	178	10	technological	technological	JJ
cord-015935-r2wd1yfa	178	11	advances	advance	NNS
cord-015935-r2wd1yfa	178	12	,	,	,
cord-015935-r2wd1yfa	178	13	a	a	DT
cord-015935-r2wd1yfa	178	14	genetic	genetic	JJ
cord-015935-r2wd1yfa	178	15	cause	cause	NN
cord-015935-r2wd1yfa	178	16	can	can	MD
cord-015935-r2wd1yfa	178	17	be	be	VB
cord-015935-r2wd1yfa	178	18	attributed	attribute	VBN
cord-015935-r2wd1yfa	178	19	to	to	IN
cord-015935-r2wd1yfa	178	20	only	only	RB
cord-015935-r2wd1yfa	178	21	10	10	CD
cord-015935-r2wd1yfa	178	22	-	-	SYM
cord-015935-r2wd1yfa	178	23	20	20	CD
cord-015935-r2wd1yfa	178	24	%	%	NN
cord-015935-r2wd1yfa	178	25	of	of	IN
cord-015935-r2wd1yfa	178	26	all	all	DT
cord-015935-r2wd1yfa	178	27	cases	case	NNS
cord-015935-r2wd1yfa	178	28	(	(	-LRB-
cord-015935-r2wd1yfa	178	29	reviewed	review	VBN
cord-015935-r2wd1yfa	178	30	in	in	IN
cord-015935-r2wd1yfa	178	31	Abrahams	Abrahams	NNP
cord-015935-r2wd1yfa	178	32	&	&	CC
cord-015935-r2wd1yfa	178	33	Geschwind	Geschwind	NNP
cord-015935-r2wd1yfa	178	34	,	,	,
cord-015935-r2wd1yfa	178	35	2008	2008	CD
cord-015935-r2wd1yfa	178	36	)	)	-RRB-
cord-015935-r2wd1yfa	178	37	,	,	,
cord-015935-r2wd1yfa	178	38	with	with	IN
cord-015935-r2wd1yfa	178	39	a	a	DT
cord-015935-r2wd1yfa	178	40	recent	recent	JJ
cord-015935-r2wd1yfa	178	41	report	report	NN
cord-015935-r2wd1yfa	178	42	suggesting	suggest	VBG
cord-015935-r2wd1yfa	178	43	a	a	DT
cord-015935-r2wd1yfa	178	44	genetic	genetic	JJ
cord-015935-r2wd1yfa	178	45	cause	cause	NN
cord-015935-r2wd1yfa	178	46	can	can	MD
cord-015935-r2wd1yfa	178	47	be	be	VB
cord-015935-r2wd1yfa	178	48	uncovered	uncover	VBN
cord-015935-r2wd1yfa	178	49	in	in	IN
cord-015935-r2wd1yfa	178	50	up	up	IN
cord-015935-r2wd1yfa	178	51	to	to	TO
cord-015935-r2wd1yfa	178	52	40	40	CD
cord-015935-r2wd1yfa	178	53	%	%	NN
cord-015935-r2wd1yfa	178	54	of	of	IN
cord-015935-r2wd1yfa	178	55	cases	case	NNS
cord-015935-r2wd1yfa	178	56	(	(	-LRB-
cord-015935-r2wd1yfa	178	57	Schaefer	Schaefer	NNP
cord-015935-r2wd1yfa	178	58	&	&	CC
cord-015935-r2wd1yfa	178	59	Lutz	Lutz	NNP
cord-015935-r2wd1yfa	178	60	,	,	,
cord-015935-r2wd1yfa	178	61	2006	2006	CD
cord-015935-r2wd1yfa	178	62	)	)	-RRB-
cord-015935-r2wd1yfa	178	63	.	.	.
cord-015935-r2wd1yfa	179	1	Further	further	RB
cord-015935-r2wd1yfa	179	2	,	,	,
cord-015935-r2wd1yfa	179	3	Abraham	Abraham	NNP
cord-015935-r2wd1yfa	179	4	and	and	CC
cord-015935-r2wd1yfa	179	5	Geschwind	Geschwind	NNP
cord-015935-r2wd1yfa	179	6	(	(	-LRB-
cord-015935-r2wd1yfa	179	7	2008	2008	CD
cord-015935-r2wd1yfa	179	8	)	)	-RRB-
cord-015935-r2wd1yfa	179	9	state	state	NN
cord-015935-r2wd1yfa	179	10	that	that	IN
cord-015935-r2wd1yfa	179	11	no	no	DT
cord-015935-r2wd1yfa	179	12	single	single	JJ
cord-015935-r2wd1yfa	179	13	genetic	genetic	JJ
cord-015935-r2wd1yfa	179	14	cause	cause	NN
cord-015935-r2wd1yfa	179	15	accounts	account	VBZ
cord-015935-r2wd1yfa	179	16	for	for	IN
cord-015935-r2wd1yfa	179	17	more	more	JJR
cord-015935-r2wd1yfa	179	18	than	than	IN
cord-015935-r2wd1yfa	179	19	1	1	CD
cord-015935-r2wd1yfa	179	20	-	-	SYM
cord-015935-r2wd1yfa	179	21	2	2	CD
cord-015935-r2wd1yfa	179	22	%	%	NN
cord-015935-r2wd1yfa	179	23	of	of	IN
cord-015935-r2wd1yfa	179	24	cases	case	NNS
cord-015935-r2wd1yfa	179	25	-similar	-similar	.
cord-015935-r2wd1yfa	180	1	to	to	IN
cord-015935-r2wd1yfa	180	2	what	what	WP
cord-015935-r2wd1yfa	180	3	is	be	VBZ
cord-015935-r2wd1yfa	180	4	seen	see	VBN
cord-015935-r2wd1yfa	180	5	in	in	IN
cord-015935-r2wd1yfa	180	6	mental	mental	JJ
cord-015935-r2wd1yfa	180	7	retardation	retardation	NN
cord-015935-r2wd1yfa	180	8	,	,	,
cord-015935-r2wd1yfa	180	9	another	another	DT
cord-015935-r2wd1yfa	180	10	condition	condition	NN
cord-015935-r2wd1yfa	180	11	without	without	IN
cord-015935-r2wd1yfa	180	12	a	a	DT
cord-015935-r2wd1yfa	180	13	single	single	JJ
cord-015935-r2wd1yfa	180	14	genetic	genetic	JJ
cord-015935-r2wd1yfa	180	15	cause	cause	NN
cord-015935-r2wd1yfa	180	16	.	.	.
cord-015935-r2wd1yfa	181	1	While	while	IN
cord-015935-r2wd1yfa	181	2	numerous	numerous	JJ
cord-015935-r2wd1yfa	181	3	studies	study	NNS
cord-015935-r2wd1yfa	181	4	identifying	identify	VBG
cord-015935-r2wd1yfa	181	5	candidate	candidate	NN
cord-015935-r2wd1yfa	181	6	genes	gene	NNS
cord-015935-r2wd1yfa	181	7	or	or	CC
cord-015935-r2wd1yfa	181	8	makers	maker	NNS
cord-015935-r2wd1yfa	181	9	have	have	VBP
cord-015935-r2wd1yfa	181	10	been	be	VBN
cord-015935-r2wd1yfa	181	11	reported	report	VBN
cord-015935-r2wd1yfa	181	12	,	,	,
cord-015935-r2wd1yfa	181	13	very	very	RB
cord-015935-r2wd1yfa	181	14	few	few	JJ
cord-015935-r2wd1yfa	181	15	studies	study	NNS
cord-015935-r2wd1yfa	181	16	have	have	VBP
cord-015935-r2wd1yfa	181	17	been	be	VBN
cord-015935-r2wd1yfa	181	18	replicated	replicate	VBN
cord-015935-r2wd1yfa	182	1	(	(	-LRB-
cord-015935-r2wd1yfa	182	2	Losh	Losh	NNP
cord-015935-r2wd1yfa	182	3	et	et	NNP
cord-015935-r2wd1yfa	182	4	al	al	NNP
cord-015935-r2wd1yfa	182	5	.	.	NNP
cord-015935-r2wd1yfa	182	6	,	,	,
cord-015935-r2wd1yfa	182	7	2008	2008	CD
cord-015935-r2wd1yfa	182	8	)	)	-RRB-
cord-015935-r2wd1yfa	182	9	.	.	.
cord-015935-r2wd1yfa	183	1	Reasons	reason	NNS
cord-015935-r2wd1yfa	183	2	to	to	TO
cord-015935-r2wd1yfa	183	3	explain	explain	VB
cord-015935-r2wd1yfa	183	4	why	why	WRB
cord-015935-r2wd1yfa	183	5	candidates	candidate	NNS
cord-015935-r2wd1yfa	183	6	have	have	VBP
cord-015935-r2wd1yfa	183	7	not	not	RB
cord-015935-r2wd1yfa	183	8	been	be	VBN
cord-015935-r2wd1yfa	183	9	agreed	agree	VBN
cord-015935-r2wd1yfa	183	10	upon	upon	IN
cord-015935-r2wd1yfa	183	11	include	include	VBP
cord-015935-r2wd1yfa	183	12	the	the	DT
cord-015935-r2wd1yfa	183	13	initial	initial	JJ
cord-015935-r2wd1yfa	183	14	lack	lack	NN
cord-015935-r2wd1yfa	183	15	of	of	IN
cord-015935-r2wd1yfa	183	16	uniform	uniform	JJ
cord-015935-r2wd1yfa	183	17	diagnostic	diagnostic	JJ
cord-015935-r2wd1yfa	183	18	criteria	criterion	NNS
cord-015935-r2wd1yfa	183	19	(	(	-LRB-
cord-015935-r2wd1yfa	183	20	strict	strict	JJ
cord-015935-r2wd1yfa	183	21	vs.	vs.	FW
cord-015935-r2wd1yfa	183	22	broad	broad	JJ
cord-015935-r2wd1yfa	183	23	definition	definition	NN
cord-015935-r2wd1yfa	183	24	)	)	-RRB-
cord-015935-r2wd1yfa	183	25	,	,	,
cord-015935-r2wd1yfa	183	26	limited	limited	JJ
cord-015935-r2wd1yfa	183	27	power	power	NN
cord-015935-r2wd1yfa	183	28	,	,	,
cord-015935-r2wd1yfa	183	29	varying	vary	VBG
cord-015935-r2wd1yfa	183	30	methodology	methodology	NN
cord-015935-r2wd1yfa	183	31	(	(	-LRB-
cord-015935-r2wd1yfa	184	1	Losh	Losh	NNP
cord-015935-r2wd1yfa	184	2	et	et	NNP
cord-015935-r2wd1yfa	184	3	al	al	NNP
cord-015935-r2wd1yfa	184	4	.	.	NNP
cord-015935-r2wd1yfa	184	5	,	,	,
cord-015935-r2wd1yfa	184	6	2008	2008	CD
cord-015935-r2wd1yfa	184	7	)	)	-RRB-
cord-015935-r2wd1yfa	184	8	,	,	,
cord-015935-r2wd1yfa	184	9	and	and	CC
cord-015935-r2wd1yfa	184	10	neglect	neglect	NN
cord-015935-r2wd1yfa	184	11	of	of	IN
cord-015935-r2wd1yfa	184	12	epigenetic	epigenetic	JJ
cord-015935-r2wd1yfa	184	13	factors	factor	NNS
cord-015935-r2wd1yfa	184	14	modeling	model	VBG
cord-015935-r2wd1yfa	184	15	the	the	DT
cord-015935-r2wd1yfa	184	16	disorder	disorder	NN
cord-015935-r2wd1yfa	184	17	(	(	-LRB-
cord-015935-r2wd1yfa	184	18	Lahiri	Lahiri	NNP
cord-015935-r2wd1yfa	184	19	,	,	,
cord-015935-r2wd1yfa	184	20	Maloney	Maloney	NNP
cord-015935-r2wd1yfa	184	21	,	,	,
cord-015935-r2wd1yfa	184	22	&	&	CC
cord-015935-r2wd1yfa	184	23	Zawia	Zawia	NNP
cord-015935-r2wd1yfa	184	24	,	,	,
cord-015935-r2wd1yfa	184	25	2009	2009	CD
cord-015935-r2wd1yfa	184	26	)	)	-RRB-
cord-015935-r2wd1yfa	184	27	.	.	.
cord-015935-r2wd1yfa	185	1	Further	further	RB
cord-015935-r2wd1yfa	185	2	,	,	,
cord-015935-r2wd1yfa	185	3	as	as	IN
cord-015935-r2wd1yfa	185	4	with	with	IN
cord-015935-r2wd1yfa	185	5	other	other	JJ
cord-015935-r2wd1yfa	185	6	conditions	condition	NNS
cord-015935-r2wd1yfa	185	7	with	with	IN
cord-015935-r2wd1yfa	185	8	a	a	DT
cord-015935-r2wd1yfa	185	9	strong	strong	JJ
cord-015935-r2wd1yfa	185	10	heritable	heritable	JJ
cord-015935-r2wd1yfa	185	11	component	component	NN
cord-015935-r2wd1yfa	185	12	,	,	,
cord-015935-r2wd1yfa	185	13	it	-PRON-	PRP
cord-015935-r2wd1yfa	185	14	appears	appear	VBZ
cord-015935-r2wd1yfa	185	15	that	that	IN
cord-015935-r2wd1yfa	185	16	different	different	JJ
cord-015935-r2wd1yfa	185	17	genes	gene	NNS
cord-015935-r2wd1yfa	185	18	may	may	MD
cord-015935-r2wd1yfa	185	19	contribute	contribute	VB
cord-015935-r2wd1yfa	185	20	to	to	IN
cord-015935-r2wd1yfa	185	21	distinct	distinct	JJ
cord-015935-r2wd1yfa	185	22	components	component	NNS
cord-015935-r2wd1yfa	185	23	of	of	IN
cord-015935-r2wd1yfa	185	24	the	the	DT
cord-015935-r2wd1yfa	185	25	condition	condition	NN
cord-015935-r2wd1yfa	185	26	which	which	WDT
cord-015935-r2wd1yfa	185	27	gives	give	VBZ
cord-015935-r2wd1yfa	185	28	rise	rise	NN
cord-015935-r2wd1yfa	185	29	to	to	IN
cord-015935-r2wd1yfa	185	30	the	the	DT
cord-015935-r2wd1yfa	185	31	full	full	JJ
cord-015935-r2wd1yfa	185	32	disorder	disorder	NN
cord-015935-r2wd1yfa	185	33	through	through	IN
cord-015935-r2wd1yfa	185	34	concerted	concerted	JJ
cord-015935-r2wd1yfa	185	35	actions	action	NNS
cord-015935-r2wd1yfa	185	36	(	(	-LRB-
cord-015935-r2wd1yfa	185	37	Losh	Losh	NNP
cord-015935-r2wd1yfa	185	38	et	et	NNP
cord-015935-r2wd1yfa	185	39	al	al	NNP
cord-015935-r2wd1yfa	185	40	.	.	NNP
cord-015935-r2wd1yfa	185	41	,	,	,
cord-015935-r2wd1yfa	185	42	2008	2008	CD
cord-015935-r2wd1yfa	185	43	;	;	:
cord-015935-r2wd1yfa	185	44	Pickles	Pickles	NNPS
cord-015935-r2wd1yfa	185	45	et	et	NNP
cord-015935-r2wd1yfa	185	46	al	al	NNP
cord-015935-r2wd1yfa	185	47	.	.	NNP
cord-015935-r2wd1yfa	185	48	,	,	,
cord-015935-r2wd1yfa	185	49	1995	1995	CD
cord-015935-r2wd1yfa	185	50	)	)	-RRB-
cord-015935-r2wd1yfa	185	51	.	.	.
cord-015935-r2wd1yfa	186	1	Consequently	consequently	RB
cord-015935-r2wd1yfa	186	2	,	,	,
cord-015935-r2wd1yfa	186	3	it	-PRON-	PRP
cord-015935-r2wd1yfa	186	4	has	have	VBZ
cord-015935-r2wd1yfa	186	5	been	be	VBN
cord-015935-r2wd1yfa	186	6	said	say	VBN
cord-015935-r2wd1yfa	186	7	that	that	IN
cord-015935-r2wd1yfa	186	8	linkage	linkage	NN
cord-015935-r2wd1yfa	186	9	technology	technology	NN
cord-015935-r2wd1yfa	186	10	has	have	VBZ
cord-015935-r2wd1yfa	186	11	not	not	RB
cord-015935-r2wd1yfa	186	12	"	"	``
cord-015935-r2wd1yfa	186	13	found	find	VBN
cord-015935-r2wd1yfa	186	14	the	the	DT
cord-015935-r2wd1yfa	186	15	autism	autism	NN
cord-015935-r2wd1yfa	186	16	gene	gene	NN
cord-015935-r2wd1yfa	186	17	,	,	,
cord-015935-r2wd1yfa	186	18	"	"	''
cord-015935-r2wd1yfa	186	19	but	but	CC
cord-015935-r2wd1yfa	186	20	rather	rather	RB
cord-015935-r2wd1yfa	186	21	it	-PRON-	PRP
cord-015935-r2wd1yfa	186	22	demonstrated	demonstrate	VBD
cord-015935-r2wd1yfa	186	23	that	that	IN
cord-015935-r2wd1yfa	186	24	more	more	RBR
cord-015935-r2wd1yfa	186	25	powerful	powerful	JJ
cord-015935-r2wd1yfa	186	26	technology	technology	NN
cord-015935-r2wd1yfa	186	27	is	be	VBZ
cord-015935-r2wd1yfa	186	28	necessary	necessary	JJ
cord-015935-r2wd1yfa	186	29	to	to	TO
cord-015935-r2wd1yfa	186	30	explain	explain	VB
cord-015935-r2wd1yfa	186	31	the	the	DT
cord-015935-r2wd1yfa	186	32	multiple	multiple	JJ
cord-015935-r2wd1yfa	186	33	genes	gene	NNS
cord-015935-r2wd1yfa	186	34	associated	associate	VBN
cord-015935-r2wd1yfa	186	35	with	with	IN
cord-015935-r2wd1yfa	186	36	autism	autism	NN
cord-015935-r2wd1yfa	186	37	(	(	-LRB-
cord-015935-r2wd1yfa	186	38	Abrahams	Abrahams	NNP
cord-015935-r2wd1yfa	186	39	&	&	CC
cord-015935-r2wd1yfa	186	40	Geschwind	Geschwind	NNP
cord-015935-r2wd1yfa	186	41	,	,	,
cord-015935-r2wd1yfa	186	42	2008	2008	CD
cord-015935-r2wd1yfa	186	43	)	)	-RRB-
cord-015935-r2wd1yfa	186	44	.	.	.
cord-015935-r2wd1yfa	187	1	No	no	DT
cord-015935-r2wd1yfa	187	2	one	one	NN
cord-015935-r2wd1yfa	187	3	knows	know	VBZ
cord-015935-r2wd1yfa	187	4	just	just	RB
cord-015935-r2wd1yfa	187	5	how	how	WRB
cord-015935-r2wd1yfa	187	6	heterogeneous	heterogeneous	JJ
cord-015935-r2wd1yfa	187	7	the	the	DT
cord-015935-r2wd1yfa	187	8	syndrome	syndrome	NN
cord-015935-r2wd1yfa	187	9	is	be	VBZ
cord-015935-r2wd1yfa	187	10	likely	likely	JJ
cord-015935-r2wd1yfa	187	11	to	to	TO
cord-015935-r2wd1yfa	187	12	be	be	VB
cord-015935-r2wd1yfa	187	13	,	,	,
cord-015935-r2wd1yfa	187	14	that	that	RB
cord-015935-r2wd1yfa	187	15	is	is	RB
cord-015935-r2wd1yfa	187	16	,	,	,
cord-015935-r2wd1yfa	187	17	how	how	WRB
cord-015935-r2wd1yfa	187	18	many	many	JJ
cord-015935-r2wd1yfa	187	19	genes	gene	NNS
cord-015935-r2wd1yfa	187	20	or	or	CC
cord-015935-r2wd1yfa	187	21	regions	region	NNS
cord-015935-r2wd1yfa	187	22	of	of	IN
cord-015935-r2wd1yfa	187	23	DNA	dna	NN
cord-015935-r2wd1yfa	187	24	(	(	-LRB-
cord-015935-r2wd1yfa	187	25	loci	locus	NNS
cord-015935-r2wd1yfa	187	26	)	)	-RRB-
cord-015935-r2wd1yfa	187	27	may	may	MD
cord-015935-r2wd1yfa	187	28	contribute	contribute	VB
cord-015935-r2wd1yfa	187	29	either	either	CC
cord-015935-r2wd1yfa	187	30	within	within	IN
cord-015935-r2wd1yfa	187	31	a	a	DT
cord-015935-r2wd1yfa	187	32	single	single	JJ
cord-015935-r2wd1yfa	187	33	individual	individual	NN
cord-015935-r2wd1yfa	187	34	or	or	CC
cord-015935-r2wd1yfa	187	35	among	among	IN
cord-015935-r2wd1yfa	187	36	the	the	DT
cord-015935-r2wd1yfa	187	37	entire	entire	JJ
cord-015935-r2wd1yfa	187	38	group	group	NN
cord-015935-r2wd1yfa	187	39	of	of	IN
cord-015935-r2wd1yfa	187	40	affected	affect	VBN
cord-015935-r2wd1yfa	187	41	individuals	individual	NNS
cord-015935-r2wd1yfa	187	42	.	.	.
cord-015935-r2wd1yfa	188	1	Some	some	DT
cord-015935-r2wd1yfa	188	2	of	of	IN
cord-015935-r2wd1yfa	188	3	the	the	DT
cord-015935-r2wd1yfa	188	4	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	188	5	regions	region	NNS
cord-015935-r2wd1yfa	188	6	and	and	CC
cord-015935-r2wd1yfa	188	7	genes	gene	NNS
cord-015935-r2wd1yfa	188	8	that	that	WDT
cord-015935-r2wd1yfa	188	9	have	have	VBP
cord-015935-r2wd1yfa	188	10	been	be	VBN
cord-015935-r2wd1yfa	188	11	associated	associate	VBN
cord-015935-r2wd1yfa	188	12	with	with	IN
cord-015935-r2wd1yfa	188	13	autism	autism	NN
cord-015935-r2wd1yfa	188	14	are	be	VBP
cord-015935-r2wd1yfa	188	15	summarized	summarize	VBN
cord-015935-r2wd1yfa	188	16	in	in	IN
cord-015935-r2wd1yfa	188	17	Table	Table	NNP
cord-015935-r2wd1yfa	188	18	6	6	CD
cord-015935-r2wd1yfa	188	19	.1	.1	NNS
cord-015935-r2wd1yfa	188	20	and	and	CC
cord-015935-r2wd1yfa	188	21	will	will	MD
cord-015935-r2wd1yfa	188	22	be	be	VB
cord-015935-r2wd1yfa	188	23	addressed	address	VBN
cord-015935-r2wd1yfa	188	24	herein	herein	RB
cord-015935-r2wd1yfa	188	25	.	.	.
cord-015935-r2wd1yfa	189	1	In	in	IN
cord-015935-r2wd1yfa	189	2	addition	addition	NN
cord-015935-r2wd1yfa	189	3	,	,	,
cord-015935-r2wd1yfa	189	4	it	-PRON-	PRP
cord-015935-r2wd1yfa	189	5	is	be	VBZ
cord-015935-r2wd1yfa	189	6	important	important	JJ
cord-015935-r2wd1yfa	189	7	to	to	TO
cord-015935-r2wd1yfa	189	8	distinguish	distinguish	VB
cord-015935-r2wd1yfa	189	9	between	between	IN
cord-015935-r2wd1yfa	189	10	locus	locus	NN
cord-015935-r2wd1yfa	189	11	heterogeneity	heterogeneity	NN
cord-015935-r2wd1yfa	189	12	,	,	,
cord-015935-r2wd1yfa	189	13	which	which	WDT
cord-015935-r2wd1yfa	189	14	refers	refer	VBZ
cord-015935-r2wd1yfa	189	15	to	to	IN
cord-015935-r2wd1yfa	189	16	a	a	DT
cord-015935-r2wd1yfa	189	17	variation	variation	NN
cord-015935-r2wd1yfa	189	18	at	at	IN
cord-015935-r2wd1yfa	189	19	many	many	JJ
cord-015935-r2wd1yfa	189	20	different	different	JJ
cord-015935-r2wd1yfa	189	21	genes	gene	NNS
cord-015935-r2wd1yfa	189	22	or	or	CC
cord-015935-r2wd1yfa	189	23	loci	locus	NNS
cord-015935-r2wd1yfa	189	24	resulting	result	VBG
cord-015935-r2wd1yfa	189	25	in	in	IN
cord-015935-r2wd1yfa	189	26	a	a	DT
cord-015935-r2wd1yfa	189	27	similar	similar	JJ
cord-015935-r2wd1yfa	189	28	phenotype	phenotype	NN
cord-015935-r2wd1yfa	189	29	,	,	,
cord-015935-r2wd1yfa	189	30	and	and	CC
cord-015935-r2wd1yfa	189	31	allelic	allelic	JJ
cord-015935-r2wd1yfa	189	32	heterogeneity	heterogeneity	NN
cord-015935-r2wd1yfa	189	33	,	,	,
cord-015935-r2wd1yfa	189	34	which	which	WDT
cord-015935-r2wd1yfa	189	35	refers	refer	VBZ
cord-015935-r2wd1yfa	189	36	to	to	IN
cord-015935-r2wd1yfa	189	37	different	different	JJ
cord-015935-r2wd1yfa	189	38	variations	variation	NNS
cord-015935-r2wd1yfa	189	39	or	or	CC
cord-015935-r2wd1yfa	189	40	mutations	mutation	NNS
cord-015935-r2wd1yfa	189	41	at	at	IN
cord-015935-r2wd1yfa	189	42	the	the	DT
cord-015935-r2wd1yfa	189	43	same	same	JJ
cord-015935-r2wd1yfa	189	44	locus	locus	NN
cord-015935-r2wd1yfa	189	45	leading	lead	VBG
cord-015935-r2wd1yfa	189	46	to	to	IN
cord-015935-r2wd1yfa	189	47	an	an	DT
cord-015935-r2wd1yfa	189	48	identical	identical	JJ
cord-015935-r2wd1yfa	189	49	or	or	CC
cord-015935-r2wd1yfa	189	50	overlapping	overlap	VBG
cord-015935-r2wd1yfa	189	51	clinical	clinical	JJ
cord-015935-r2wd1yfa	189	52	picture	picture	NN
cord-015935-r2wd1yfa	189	53	.	.	.
cord-015935-r2wd1yfa	190	1	Accumulating	accumulate	VBG
cord-015935-r2wd1yfa	190	2	evidence	evidence	NN
cord-015935-r2wd1yfa	190	3	suggest	suggest	VBP
cord-015935-r2wd1yfa	190	4	that	that	IN
cord-015935-r2wd1yfa	190	5	both	both	DT
cord-015935-r2wd1yfa	190	6	play	play	VB
cord-015935-r2wd1yfa	190	7	a	a	DT
cord-015935-r2wd1yfa	190	8	role	role	NN
cord-015935-r2wd1yfa	190	9	in	in	IN
cord-015935-r2wd1yfa	190	10	autism	autism	NN
cord-015935-r2wd1yfa	190	11	(	(	-LRB-
cord-015935-r2wd1yfa	190	12	O'Roak	O'Roak	NNP
cord-015935-r2wd1yfa	190	13	&	&	CC
cord-015935-r2wd1yfa	190	14	State	State	NNP
cord-015935-r2wd1yfa	190	15	,	,	,
cord-015935-r2wd1yfa	190	16	2008	2008	CD
cord-015935-r2wd1yfa	190	17	)	)	-RRB-
cord-015935-r2wd1yfa	190	18	.	.	.
cord-015935-r2wd1yfa	191	1	Recently	recently	RB
cord-015935-r2wd1yfa	191	2	,	,	,
cord-015935-r2wd1yfa	191	3	a	a	DT
cord-015935-r2wd1yfa	191	4	rare	rare	JJ
cord-015935-r2wd1yfa	191	5	-	-	HYPH
cord-015935-r2wd1yfa	191	6	variant	variant	NN
cord-015935-r2wd1yfa	191	7	common	common	JJ
cord-015935-r2wd1yfa	191	8	disease	disease	NN
cord-015935-r2wd1yfa	191	9	model	model	NN
cord-015935-r2wd1yfa	191	10	has	have	VBZ
cord-015935-r2wd1yfa	191	11	been	be	VBN
cord-015935-r2wd1yfa	191	12	introduced	introduce	VBN
cord-015935-r2wd1yfa	191	13	(	(	-LRB-
cord-015935-r2wd1yfa	191	14	O	o	UH
cord-015935-r2wd1yfa	191	15	'	'	''
cord-015935-r2wd1yfa	191	16	Roak	Roak	NNP
cord-015935-r2wd1yfa	191	17	&	&	CC
cord-015935-r2wd1yfa	191	18	State	State	NNP
cord-015935-r2wd1yfa	191	19	,	,	,
cord-015935-r2wd1yfa	191	20	2008	2008	CD
cord-015935-r2wd1yfa	191	21	)	)	-RRB-
cord-015935-r2wd1yfa	191	22	.	.	.
cord-015935-r2wd1yfa	192	1	In	in	IN
cord-015935-r2wd1yfa	192	2	this	this	DT
cord-015935-r2wd1yfa	192	3	model	model	NN
cord-015935-r2wd1yfa	192	4	,	,	,
cord-015935-r2wd1yfa	192	5	rare	rare	JJ
cord-015935-r2wd1yfa	192	6	genes	gene	NNS
cord-015935-r2wd1yfa	192	7	explain	explain	VBP
cord-015935-r2wd1yfa	192	8	the	the	DT
cord-015935-r2wd1yfa	192	9	common	common	JJ
cord-015935-r2wd1yfa	192	10	disease	disease	NN
cord-015935-r2wd1yfa	192	11	of	of	IN
cord-015935-r2wd1yfa	192	12	autism	autism	NN
cord-015935-r2wd1yfa	192	13	.	.	.
cord-015935-r2wd1yfa	193	1	This	this	DT
cord-015935-r2wd1yfa	193	2	makes	make	VBZ
cord-015935-r2wd1yfa	193	3	sense	sense	NN
cord-015935-r2wd1yfa	193	4	in	in	IN
cord-015935-r2wd1yfa	193	5	the	the	DT
cord-015935-r2wd1yfa	193	6	Darwinian	darwinian	JJ
cord-015935-r2wd1yfa	193	7	tradition	tradition	NN
cord-015935-r2wd1yfa	193	8	that	that	IN
cord-015935-r2wd1yfa	193	9	a	a	DT
cord-015935-r2wd1yfa	193	10	deleterious	deleterious	JJ
cord-015935-r2wd1yfa	193	11	change	change	NN
cord-015935-r2wd1yfa	193	12	in	in	IN
cord-015935-r2wd1yfa	193	13	the	the	DT
cord-015935-r2wd1yfa	193	14	human	human	JJ
cord-015935-r2wd1yfa	193	15	genome	genome	NN
cord-015935-r2wd1yfa	193	16	leads	lead	VBZ
cord-015935-r2wd1yfa	193	17	to	to	IN
cord-015935-r2wd1yfa	193	18	reduced	reduce	VBN
cord-015935-r2wd1yfa	193	19	fitness	fitness	NN
cord-015935-r2wd1yfa	193	20	and	and	CC
cord-015935-r2wd1yfa	193	21	that	that	IN
cord-015935-r2wd1yfa	193	22	this	this	DT
cord-015935-r2wd1yfa	193	23	would	would	MD
cord-015935-r2wd1yfa	193	24	not	not	RB
cord-015935-r2wd1yfa	193	25	be	be	VB
cord-015935-r2wd1yfa	193	26	likely	likely	JJ
cord-015935-r2wd1yfa	193	27	to	to	TO
cord-015935-r2wd1yfa	193	28	propagate	propagate	VB
cord-015935-r2wd1yfa	193	29	within	within	IN
cord-015935-r2wd1yfa	193	30	a	a	DT
cord-015935-r2wd1yfa	193	31	population	population	NN
cord-015935-r2wd1yfa	193	32	.	.	.
cord-015935-r2wd1yfa	194	1	Autism	autism	NN
cord-015935-r2wd1yfa	194	2	fits	fit	VBZ
cord-015935-r2wd1yfa	194	3	the	the	DT
cord-015935-r2wd1yfa	194	4	rare	rare	JJ
cord-015935-r2wd1yfa	194	5	gene	gene	NN
cord-015935-r2wd1yfa	194	6	-	-	HYPH
cord-015935-r2wd1yfa	194	7	common	common	JJ
cord-015935-r2wd1yfa	194	8	disease	disease	NN
cord-015935-r2wd1yfa	194	9	model	model	NN
cord-015935-r2wd1yfa	194	10	as	as	IN
cord-015935-r2wd1yfa	194	11	it	-PRON-	PRP
cord-015935-r2wd1yfa	194	12	begins	begin	VBZ
cord-015935-r2wd1yfa	194	13	early	early	RB
cord-015935-r2wd1yfa	194	14	in	in	IN
cord-015935-r2wd1yfa	194	15	life	life	NN
cord-015935-r2wd1yfa	194	16	,	,	,
cord-015935-r2wd1yfa	194	17	impairs	impair	VBZ
cord-015935-r2wd1yfa	194	18	social	social	JJ
cord-015935-r2wd1yfa	194	19	interactions	interaction	NNS
cord-015935-r2wd1yfa	194	20	,	,	,
cord-015935-r2wd1yfa	194	21	and	and	CC
cord-015935-r2wd1yfa	194	22	is	be	VBZ
cord-015935-r2wd1yfa	194	23	associated	associate	VBN
cord-015935-r2wd1yfa	194	24	with	with	IN
cord-015935-r2wd1yfa	194	25	mental	mental	JJ
cord-015935-r2wd1yfa	194	26	retardation	retardation	NN
cord-015935-r2wd1yfa	194	27	which	which	WDT
cord-015935-r2wd1yfa	194	28	impacts	impact	VBZ
cord-015935-r2wd1yfa	194	29	reproductive	reproductive	JJ
cord-015935-r2wd1yfa	194	30	fitness	fitness	NN
cord-015935-r2wd1yfa	194	31	(	(	-LRB-
cord-015935-r2wd1yfa	194	32	O'Roak	O'Roak	NNP
cord-015935-r2wd1yfa	194	33	&	&	CC
cord-015935-r2wd1yfa	194	34	State	State	NNP
cord-015935-r2wd1yfa	194	35	,	,	,
cord-015935-r2wd1yfa	194	36	2008	2008	CD
cord-015935-r2wd1yfa	194	37	)	)	-RRB-
cord-015935-r2wd1yfa	194	38	.	.	.
cord-015935-r2wd1yfa	195	1	The	the	DT
cord-015935-r2wd1yfa	195	2	large	large	JJ
cord-015935-r2wd1yfa	195	3	difference	difference	NN
cord-015935-r2wd1yfa	195	4	seen	see	VBN
cord-015935-r2wd1yfa	195	5	between	between	IN
cord-015935-r2wd1yfa	195	6	monozygotic	monozygotic	NNS
cord-015935-r2wd1yfa	195	7	and	and	CC
cord-015935-r2wd1yfa	195	8	dizygotic	dizygotic	JJ
cord-015935-r2wd1yfa	195	9	concordance	concordance	NN
cord-015935-r2wd1yfa	195	10	rates	rate	NNS
cord-015935-r2wd1yfa	195	11	is	be	VBZ
cord-015935-r2wd1yfa	195	12	consistent	consistent	JJ
cord-015935-r2wd1yfa	195	13	with	with	IN
cord-015935-r2wd1yfa	195	14	de	de	FW
cord-015935-r2wd1yfa	195	15	novo	novo	NNP
cord-015935-r2wd1yfa	195	16	(	(	-LRB-
cord-015935-r2wd1yfa	195	17	rare	rare	JJ
cord-015935-r2wd1yfa	195	18	gene	gene	NN
cord-015935-r2wd1yfa	195	19	)	)	-RRB-
cord-015935-r2wd1yfa	195	20	mutation	mutation	NN
cord-015935-r2wd1yfa	195	21	.	.	.
cord-015935-r2wd1yfa	196	1	It	-PRON-	PRP
cord-015935-r2wd1yfa	196	2	appears	appear	VBZ
cord-015935-r2wd1yfa	196	3	that	that	IN
cord-015935-r2wd1yfa	196	4	simplex	simplex	JJ
cord-015935-r2wd1yfa	196	5	families	family	NNS
cord-015935-r2wd1yfa	196	6	demonstrate	demonstrate	VBP
cord-015935-r2wd1yfa	196	7	de	de	IN
cord-015935-r2wd1yfa	196	8	novo	novo	NNP
cord-015935-r2wd1yfa	196	9	mutations	mutation	NNS
cord-015935-r2wd1yfa	196	10	more	more	JJR
cord-015935-r2wd1yfa	196	11	frequentlywith	frequentlywith	NNP
cord-015935-r2wd1yfa	196	12	one	one	CD
cord-015935-r2wd1yfa	196	13	family	family	NN
cord-015935-r2wd1yfa	196	14	member	member	NN
cord-015935-r2wd1yfa	196	15	with	with	IN
cord-015935-r2wd1yfa	196	16	autism	autism	NN
cord-015935-r2wd1yfa	197	1	(	(	-LRB-
cord-015935-r2wd1yfa	197	2	Sebat	Sebat	NNP
cord-015935-r2wd1yfa	197	3	et	et	NNP
cord-015935-r2wd1yfa	197	4	al	al	NNP
cord-015935-r2wd1yfa	197	5	.	.	NNP
cord-015935-r2wd1yfa	197	6	,	,	,
cord-015935-r2wd1yfa	197	7	2007	2007	CD
cord-015935-r2wd1yfa	197	8	)	)	-RRB-
cord-015935-r2wd1yfa	197	9	whereas	whereas	IN
cord-015935-r2wd1yfa	197	10	multiplex	multiplex	JJ
cord-015935-r2wd1yfa	197	11	families	family	NNS
cord-015935-r2wd1yfa	197	12	demonstrate	demonstrate	VBP
cord-015935-r2wd1yfa	197	13	transmitted	transmit	VBN
cord-015935-r2wd1yfa	197	14	variants	variant	NNS
cord-015935-r2wd1yfa	197	15	(	(	-LRB-
cord-015935-r2wd1yfa	197	16	Bakkaloglu	Bakkaloglu	NNP
cord-015935-r2wd1yfa	197	17	et	et	NNP
cord-015935-r2wd1yfa	197	18	al	al	NNP
cord-015935-r2wd1yfa	197	19	.	.	NNP
cord-015935-r2wd1yfa	197	20	,	,	,
cord-015935-r2wd1yfa	197	21	2008	2008	CD
cord-015935-r2wd1yfa	197	22	)	)	-RRB-
cord-015935-r2wd1yfa	197	23	.	.	.
cord-015935-r2wd1yfa	198	1	The	the	DT
cord-015935-r2wd1yfa	198	2	search	search	NN
cord-015935-r2wd1yfa	198	3	for	for	IN
cord-015935-r2wd1yfa	198	4	rare	rare	JJ
cord-015935-r2wd1yfa	198	5	variants	variant	NNS
cord-015935-r2wd1yfa	198	6	has	have	VBZ
cord-015935-r2wd1yfa	198	7	led	lead	VBN
cord-015935-r2wd1yfa	198	8	to	to	IN
cord-015935-r2wd1yfa	198	9	the	the	DT
cord-015935-r2wd1yfa	198	10	study	study	NN
cord-015935-r2wd1yfa	198	11	of	of	IN
cord-015935-r2wd1yfa	198	12	families	family	NNS
cord-015935-r2wd1yfa	198	13	that	that	WDT
cord-015935-r2wd1yfa	198	14	are	be	VBP
cord-015935-r2wd1yfa	198	15	genetically	genetically	RB
cord-015935-r2wd1yfa	198	16	isolated	isolate	VBN
cord-015935-r2wd1yfa	198	17	,	,	,
cord-015935-r2wd1yfa	198	18	with	with	IN
cord-015935-r2wd1yfa	198	19	shared	share	VBN
cord-015935-r2wd1yfa	198	20	ancestry	ancestry	NN
cord-015935-r2wd1yfa	198	21	and	and	CC
cord-015935-r2wd1yfa	198	22	prone	prone	JJ
cord-015935-r2wd1yfa	198	23	to	to	IN
cord-015935-r2wd1yfa	198	24	consanguinity	consanguinity	NN
cord-015935-r2wd1yfa	198	25	(	(	-LRB-
cord-015935-r2wd1yfa	198	26	Morrow	Morrow	NNP
cord-015935-r2wd1yfa	198	27	et	et	NNP
cord-015935-r2wd1yfa	198	28	al	al	NNP
cord-015935-r2wd1yfa	198	29	.	.	NNP
cord-015935-r2wd1yfa	198	30	,	,	,
cord-015935-r2wd1yfa	198	31	2008	2008	CD
cord-015935-r2wd1yfa	198	32	;	;	:
cord-015935-r2wd1yfa	198	33	Strauss	Strauss	NNP
cord-015935-r2wd1yfa	198	34	et	et	NNP
cord-015935-r2wd1yfa	198	35	al	al	NNP
cord-015935-r2wd1yfa	198	36	.	.	NNP
cord-015935-r2wd1yfa	198	37	,	,	,
cord-015935-r2wd1yfa	198	38	2006	2006	CD
cord-015935-r2wd1yfa	198	39	)	)	-RRB-
cord-015935-r2wd1yfa	198	40	to	to	TO
cord-015935-r2wd1yfa	198	41	locate	locate	VB
cord-015935-r2wd1yfa	198	42	recessive	recessive	JJ
cord-015935-r2wd1yfa	198	43	alleles	allele	NNS
cord-015935-r2wd1yfa	198	44	.	.	.
cord-015935-r2wd1yfa	199	1	Finally	finally	RB
cord-015935-r2wd1yfa	199	2	,	,	,
cord-015935-r2wd1yfa	199	3	rare	rare	JJ
cord-015935-r2wd1yfa	199	4	sequence	sequence	NN
cord-015935-r2wd1yfa	199	5	variations	variation	NNS
cord-015935-r2wd1yfa	199	6	have	have	VBP
cord-015935-r2wd1yfa	199	7	been	be	VBN
cord-015935-r2wd1yfa	199	8	detected	detect	VBN
cord-015935-r2wd1yfa	199	9	,	,	,
cord-015935-r2wd1yfa	199	10	thanks	thank	NNS
cord-015935-r2wd1yfa	199	11	to	to	IN
cord-015935-r2wd1yfa	199	12	improved	improved	JJ
cord-015935-r2wd1yfa	199	13	technology	technology	NN
cord-015935-r2wd1yfa	199	14	such	such	JJ
cord-015935-r2wd1yfa	199	15	as	as	IN
cord-015935-r2wd1yfa	199	16	CNV	CNV	NNP
cord-015935-r2wd1yfa	199	17	analysis	analysis	NN
cord-015935-r2wd1yfa	199	18	.	.	.
cord-015935-r2wd1yfa	200	1	Indeed	indeed	RB
cord-015935-r2wd1yfa	200	2	within	within	IN
cord-015935-r2wd1yfa	200	3	the	the	DT
cord-015935-r2wd1yfa	200	4	last	last	JJ
cord-015935-r2wd1yfa	200	5	5	5	CD
cord-015935-r2wd1yfa	200	6	-	-	SYM
cord-015935-r2wd1yfa	200	7	10	10	CD
cord-015935-r2wd1yfa	200	8	years	year	NNS
cord-015935-r2wd1yfa	200	9	,	,	,
cord-015935-r2wd1yfa	200	10	20	20	CD
cord-015935-r2wd1yfa	200	11	bona	bona	JJ
cord-015935-r2wd1yfa	200	12	fide	fide	JJ
cord-015935-r2wd1yfa	200	13	risk	risk	NN
cord-015935-r2wd1yfa	200	14	genes	gene	NNS
cord-015935-r2wd1yfa	200	15	have	have	VBP
cord-015935-r2wd1yfa	200	16	been	be	VBN
cord-015935-r2wd1yfa	200	17	identified	identify	VBN
cord-015935-r2wd1yfa	200	18	due	due	IN
cord-015935-r2wd1yfa	200	19	to	to	IN
cord-015935-r2wd1yfa	200	20	the	the	DT
cord-015935-r2wd1yfa	200	21	improved	improved	JJ
cord-015935-r2wd1yfa	200	22	technology	technology	NN
cord-015935-r2wd1yfa	200	23	developed	develop	VBN
cord-015935-r2wd1yfa	200	24	after	after	IN
cord-015935-r2wd1yfa	200	25	the	the	DT
cord-015935-r2wd1yfa	200	26	linkage	linkage	NN
cord-015935-r2wd1yfa	200	27	method	method	NN
cord-015935-r2wd1yfa	200	28	(	(	-LRB-
cord-015935-r2wd1yfa	200	29	Abrahams	Abrahams	NNP
cord-015935-r2wd1yfa	200	30	&	&	CC
cord-015935-r2wd1yfa	200	31	Geschwind	Geschwind	NNP
cord-015935-r2wd1yfa	200	32	,	,	,
cord-015935-r2wd1yfa	200	33	2008	2008	CD
cord-015935-r2wd1yfa	200	34	)	)	-RRB-
cord-015935-r2wd1yfa	200	35	.	.	.
cord-015935-r2wd1yfa	201	1	Several	several	JJ
cord-015935-r2wd1yfa	201	2	of	of	IN
cord-015935-r2wd1yfa	201	3	these	these	DT
cord-015935-r2wd1yfa	201	4	risk	risk	NN
cord-015935-r2wd1yfa	201	5	genes	gene	NNS
cord-015935-r2wd1yfa	201	6	will	will	MD
cord-015935-r2wd1yfa	201	7	be	be	VB
cord-015935-r2wd1yfa	201	8	discussed	discuss	VBN
cord-015935-r2wd1yfa	201	9	in	in	IN
cord-015935-r2wd1yfa	201	10	the	the	DT
cord-015935-r2wd1yfa	201	11	following	follow	VBG
cord-015935-r2wd1yfa	201	12	sections	section	NNS
cord-015935-r2wd1yfa	201	13	.	.	.
cord-015935-r2wd1yfa	202	1	Abrahams	Abrahams	NNP
cord-015935-r2wd1yfa	202	2	and	and	CC
cord-015935-r2wd1yfa	202	3	Geschwind	Geschwind	NNP
cord-015935-r2wd1yfa	202	4	(	(	-LRB-
cord-015935-r2wd1yfa	202	5	2008	2008	CD
cord-015935-r2wd1yfa	202	6	)	)	-RRB-
cord-015935-r2wd1yfa	202	7	write	write	VB
cord-015935-r2wd1yfa	202	8	that	that	IN
cord-015935-r2wd1yfa	202	9	two	two	CD
cord-015935-r2wd1yfa	202	10	views	view	NNS
cord-015935-r2wd1yfa	202	11	underlie	underlie	VBP
cord-015935-r2wd1yfa	202	12	genetic	genetic	JJ
cord-015935-r2wd1yfa	202	13	autism	autism	NN
cord-015935-r2wd1yfa	202	14	research	research	NN
cord-015935-r2wd1yfa	202	15	.	.	.
cord-015935-r2wd1yfa	203	1	The	the	DT
cord-015935-r2wd1yfa	203	2	first	first	JJ
cord-015935-r2wd1yfa	203	3	is	be	VBZ
cord-015935-r2wd1yfa	203	4	that	that	IN
cord-015935-r2wd1yfa	203	5	rare	rare	JJ
cord-015935-r2wd1yfa	203	6	variants	variant	NNS
cord-015935-r2wd1yfa	203	7	involve	involve	VBP
cord-015935-r2wd1yfa	203	8	an	an	DT
cord-015935-r2wd1yfa	203	9	abnormality	abnormality	NN
cord-015935-r2wd1yfa	203	10	in	in	IN
cord-015935-r2wd1yfa	203	11	a	a	DT
cord-015935-r2wd1yfa	203	12	single	single	JJ
cord-015935-r2wd1yfa	203	13	molecule	molecule	NN
cord-015935-r2wd1yfa	203	14	causing	cause	VBG
cord-015935-r2wd1yfa	203	15	the	the	DT
cord-015935-r2wd1yfa	203	16	clinical	clinical	JJ
cord-015935-r2wd1yfa	203	17	pathology	pathology	NN
cord-015935-r2wd1yfa	203	18	in	in	IN
cord-015935-r2wd1yfa	203	19	autism	autism	NN
cord-015935-r2wd1yfa	203	20	.	.	.
cord-015935-r2wd1yfa	204	1	Mendelian	mendelian	JJ
cord-015935-r2wd1yfa	204	2	inheritance	inheritance	NN
cord-015935-r2wd1yfa	204	3	(	(	-LRB-
cord-015935-r2wd1yfa	204	4	autosomal	autosomal	JJ
cord-015935-r2wd1yfa	204	5	dominant	dominant	JJ
cord-015935-r2wd1yfa	204	6	vs.	vs.	FW
cord-015935-r2wd1yfa	204	7	recessive	recessive	NN
cord-015935-r2wd1yfa	204	8	)	)	-RRB-
cord-015935-r2wd1yfa	204	9	takes	take	VBZ
cord-015935-r2wd1yfa	204	10	this	this	DT
cord-015935-r2wd1yfa	204	11	form	form	NN
cord-015935-r2wd1yfa	204	12	.	.	.
cord-015935-r2wd1yfa	205	1	Technology	technology	NN
cord-015935-r2wd1yfa	205	2	compatible	compatible	JJ
cord-015935-r2wd1yfa	205	3	with	with	IN
cord-015935-r2wd1yfa	205	4	this	this	DT
cord-015935-r2wd1yfa	205	5	approach	approach	NN
cord-015935-r2wd1yfa	205	6	includes	include	VBZ
cord-015935-r2wd1yfa	205	7	cytogenetics	cytogenetic	NNS
cord-015935-r2wd1yfa	205	8	(	(	-LRB-
cord-015935-r2wd1yfa	205	9	including	include	VBG
cord-015935-r2wd1yfa	205	10	karyotyping	karyotyping	NN
cord-015935-r2wd1yfa	205	11	and	and	CC
cord-015935-r2wd1yfa	205	12	FISH	fish	NN
cord-015935-r2wd1yfa	205	13	)	)	-RRB-
cord-015935-r2wd1yfa	205	14	,	,	,
cord-015935-r2wd1yfa	205	15	gene	gene	NNP
cord-015935-r2wd1yfa	205	16	association	association	NNP
cord-015935-r2wd1yfa	205	17	studies	study	NNS
cord-015935-r2wd1yfa	205	18	(	(	-LRB-
cord-015935-r2wd1yfa	205	19	analysis	analysis	NN
cord-015935-r2wd1yfa	205	20	of	of	IN
cord-015935-r2wd1yfa	205	21	genes	gene	NNS
cord-015935-r2wd1yfa	205	22	and	and	CC
cord-015935-r2wd1yfa	205	23	protein	protein	NN
cord-015935-r2wd1yfa	205	24	system	system	NN
cord-015935-r2wd1yfa	205	25	from	from	IN
cord-015935-r2wd1yfa	205	26	less	less	RBR
cord-015935-r2wd1yfa	205	27	complex	complex	JJ
cord-015935-r2wd1yfa	205	28	genetic	genetic	JJ
cord-015935-r2wd1yfa	205	29	syndromes	syndrome	NNS
cord-015935-r2wd1yfa	205	30	similar	similar	JJ
cord-015935-r2wd1yfa	205	31	to	to	IN
cord-015935-r2wd1yfa	205	32	autism	autism	NN
cord-015935-r2wd1yfa	205	33	such	such	JJ
cord-015935-r2wd1yfa	205	34	as	as	IN
cord-015935-r2wd1yfa	205	35	Rett	Rett	NNP
cord-015935-r2wd1yfa	205	36	and	and	CC
cord-015935-r2wd1yfa	205	37	fragile	fragile	JJ
cord-015935-r2wd1yfa	205	38	X	x	NN
cord-015935-r2wd1yfa	205	39	syndromes	syndrome	NNS
cord-015935-r2wd1yfa	205	40	)	)	-RRB-
cord-015935-r2wd1yfa	205	41	,	,	,
cord-015935-r2wd1yfa	205	42	linkage	linkage	NN
cord-015935-r2wd1yfa	205	43	studies	study	NNS
cord-015935-r2wd1yfa	205	44	(	(	-LRB-
cord-015935-r2wd1yfa	205	45	including	include	VBG
cord-015935-r2wd1yfa	205	46	genome	genome	NN
cord-015935-r2wd1yfa	205	47	screens	screen	NNS
cord-015935-r2wd1yfa	205	48	in	in	IN
cord-015935-r2wd1yfa	205	49	affected	affect	VBN
cord-015935-r2wd1yfa	205	50	sibling	sibling	NN
cord-015935-r2wd1yfa	205	51	pairs	pair	NNS
cord-015935-r2wd1yfa	205	52	)	)	-RRB-
cord-015935-r2wd1yfa	205	53	,	,	,
cord-015935-r2wd1yfa	205	54	microarray	microarray	NN
cord-015935-r2wd1yfa	205	55	technology	technology	NN
cord-015935-r2wd1yfa	205	56	,	,	,
cord-015935-r2wd1yfa	205	57	and	and	CC
cord-015935-r2wd1yfa	205	58	CNV	CNV	NNP
cord-015935-r2wd1yfa	205	59	analysis	analysis	NN
cord-015935-r2wd1yfa	205	60	.	.	.
cord-015935-r2wd1yfa	206	1	The	the	DT
cord-015935-r2wd1yfa	206	2	second	second	JJ
cord-015935-r2wd1yfa	206	3	view	view	NN
cord-015935-r2wd1yfa	206	4	involves	involve	VBZ
cord-015935-r2wd1yfa	206	5	the	the	DT
cord-015935-r2wd1yfa	206	6	study	study	NN
cord-015935-r2wd1yfa	206	7	of	of	IN
cord-015935-r2wd1yfa	206	8	independent	independent	JJ
cord-015935-r2wd1yfa	206	9	hereditary	hereditary	JJ
cord-015935-r2wd1yfa	206	10	endophenotypes	endophenotype	NNS
cord-015935-r2wd1yfa	206	11	representing	represent	VBG
cord-015935-r2wd1yfa	206	12	the	the	DT
cord-015935-r2wd1yfa	206	13	core	core	NN
cord-015935-r2wd1yfa	206	14	features	feature	NNS
cord-015935-r2wd1yfa	206	15	of	of	IN
cord-015935-r2wd1yfa	206	16	autism	autism	NN
cord-015935-r2wd1yfa	206	17	.	.	.
cord-015935-r2wd1yfa	207	1	An	an	DT
cord-015935-r2wd1yfa	207	2	endophenotype	endophenotype	NN
cord-015935-r2wd1yfa	207	3	is	be	VBZ
cord-015935-r2wd1yfa	207	4	an	an	DT
cord-015935-r2wd1yfa	207	5	operationally	operationally	RB
cord-015935-r2wd1yfa	207	6	defined	define	VBN
cord-015935-r2wd1yfa	207	7	behavioral	behavioral	JJ
cord-015935-r2wd1yfa	207	8	feature	feature	NN
cord-015935-r2wd1yfa	207	9	such	such	JJ
cord-015935-r2wd1yfa	207	10	as	as	IN
cord-015935-r2wd1yfa	207	11	age	age	NN
cord-015935-r2wd1yfa	207	12	of	of	IN
cord-015935-r2wd1yfa	207	13	first	first	JJ
cord-015935-r2wd1yfa	207	14	spoken	spoken	JJ
cord-015935-r2wd1yfa	207	15	word	word	NN
cord-015935-r2wd1yfa	207	16	.	.	.
cord-015935-r2wd1yfa	208	1	Although	although	IN
cord-015935-r2wd1yfa	208	2	there	there	EX
cord-015935-r2wd1yfa	208	3	is	be	VBZ
cord-015935-r2wd1yfa	208	4	a	a	DT
cord-015935-r2wd1yfa	208	5	general	general	JJ
cord-015935-r2wd1yfa	208	6	consensus	consensus	NN
cord-015935-r2wd1yfa	208	7	regarding	regard	VBG
cord-015935-r2wd1yfa	208	8	endophenotypes	endophenotype	NNS
cord-015935-r2wd1yfa	208	9	commonly	commonly	RB
cord-015935-r2wd1yfa	208	10	seen	see	VBN
cord-015935-r2wd1yfa	208	11	in	in	IN
cord-015935-r2wd1yfa	208	12	autism	autism	NN
cord-015935-r2wd1yfa	208	13	,	,	,
cord-015935-r2wd1yfa	208	14	the	the	DT
cord-015935-r2wd1yfa	208	15	behaviors	behavior	NNS
cord-015935-r2wd1yfa	208	16	may	may	MD
cord-015935-r2wd1yfa	208	17	not	not	RB
cord-015935-r2wd1yfa	208	18	be	be	VB
cord-015935-r2wd1yfa	208	19	specific	specific	JJ
cord-015935-r2wd1yfa	208	20	to	to	IN
cord-015935-r2wd1yfa	208	21	autism	autism	NN
cord-015935-r2wd1yfa	208	22	,	,	,
cord-015935-r2wd1yfa	208	23	as	as	IN
cord-015935-r2wd1yfa	208	24	delay	delay	NN
cord-015935-r2wd1yfa	208	25	in	in	IN
cord-015935-r2wd1yfa	208	26	language	language	NN
cord-015935-r2wd1yfa	208	27	acquisition	acquisition	NN
cord-015935-r2wd1yfa	208	28	accompanies	accompany	VBZ
cord-015935-r2wd1yfa	208	29	many	many	JJ
cord-015935-r2wd1yfa	208	30	developmental	developmental	JJ
cord-015935-r2wd1yfa	208	31	disorders	disorder	NNS
cord-015935-r2wd1yfa	208	32	.	.	.
cord-015935-r2wd1yfa	209	1	Ideally	ideally	RB
cord-015935-r2wd1yfa	209	2	,	,	,
cord-015935-r2wd1yfa	209	3	endophenotypes	endophenotype	NNS
cord-015935-r2wd1yfa	209	4	represent	represent	VBP
cord-015935-r2wd1yfa	209	5	discreet	discreet	JJ
cord-015935-r2wd1yfa	209	6	behaviors	behavior	NNS
cord-015935-r2wd1yfa	209	7	which	which	WDT
cord-015935-r2wd1yfa	209	8	do	do	VBP
cord-015935-r2wd1yfa	209	9	not	not	RB
cord-015935-r2wd1yfa	209	10	overlap	overlap	VB
cord-015935-r2wd1yfa	209	11	with	with	IN
cord-015935-r2wd1yfa	209	12	other	other	JJ
cord-015935-r2wd1yfa	209	13	behaviors	behavior	NNS
cord-015935-r2wd1yfa	209	14	from	from	IN
cord-015935-r2wd1yfa	209	15	the	the	DT
cord-015935-r2wd1yfa	209	16	autism	autism	NN
cord-015935-r2wd1yfa	209	17	core	core	NN
cord-015935-r2wd1yfa	209	18	domains	domain	NNS
cord-015935-r2wd1yfa	209	19	(	(	-LRB-
cord-015935-r2wd1yfa	209	20	i.e.	i.e.	FW
cord-015935-r2wd1yfa	209	21	,	,	,
cord-015935-r2wd1yfa	209	22	language	language	NN
cord-015935-r2wd1yfa	209	23	,	,	,
cord-015935-r2wd1yfa	209	24	socialization	socialization	NN
cord-015935-r2wd1yfa	209	25	,	,	,
cord-015935-r2wd1yfa	209	26	and	and	CC
cord-015935-r2wd1yfa	209	27	rigid	rigid	JJ
cord-015935-r2wd1yfa	209	28	behavior	behavior	NN
cord-015935-r2wd1yfa	209	29	)	)	-RRB-
cord-015935-r2wd1yfa	209	30	.	.	.
cord-015935-r2wd1yfa	210	1	For	for	IN
cord-015935-r2wd1yfa	210	2	example	example	NN
cord-015935-r2wd1yfa	210	3	,	,	,
cord-015935-r2wd1yfa	210	4	poor	poor	JJ
cord-015935-r2wd1yfa	210	5	eye	eye	NN
cord-015935-r2wd1yfa	210	6	contact	contact	NN
cord-015935-r2wd1yfa	210	7	,	,	,
cord-015935-r2wd1yfa	210	8	representing	represent	VBG
cord-015935-r2wd1yfa	210	9	a	a	DT
cord-015935-r2wd1yfa	210	10	deficit	deficit	NN
cord-015935-r2wd1yfa	210	11	with	with	IN
cord-015935-r2wd1yfa	210	12	socialization	socialization	NN
cord-015935-r2wd1yfa	210	13	,	,	,
cord-015935-r2wd1yfa	210	14	is	be	VBZ
cord-015935-r2wd1yfa	210	15	construed	construe	VBN
cord-015935-r2wd1yfa	210	16	as	as	IN
cord-015935-r2wd1yfa	210	17	being	be	VBG
cord-015935-r2wd1yfa	210	18	independent	independent	JJ
cord-015935-r2wd1yfa	210	19	of	of	IN
cord-015935-r2wd1yfa	210	20	repetitive	repetitive	JJ
cord-015935-r2wd1yfa	210	21	behaviors	behavior	NNS
cord-015935-r2wd1yfa	210	22	,	,	,
cord-015935-r2wd1yfa	210	23	thought	think	VBD
cord-015935-r2wd1yfa	210	24	to	to	TO
cord-015935-r2wd1yfa	210	25	represent	represent	VB
cord-015935-r2wd1yfa	210	26	the	the	DT
cord-015935-r2wd1yfa	210	27	rigid	rigid	JJ
cord-015935-r2wd1yfa	210	28	behavior	behavior	NN
cord-015935-r2wd1yfa	210	29	domain	domain	NN
cord-015935-r2wd1yfa	210	30	.	.	.
cord-015935-r2wd1yfa	211	1	Genetic	genetic	JJ
cord-015935-r2wd1yfa	211	2	study	study	NN
cord-015935-r2wd1yfa	211	3	of	of	IN
cord-015935-r2wd1yfa	211	4	these	these	DT
cord-015935-r2wd1yfa	211	5	discreet	discreet	JJ
cord-015935-r2wd1yfa	211	6	endophenotypes	endophenotype	NNS
cord-015935-r2wd1yfa	211	7	,	,	,
cord-015935-r2wd1yfa	211	8	largely	largely	RB
cord-015935-r2wd1yfa	211	9	undertaken	undertake	VBN
cord-015935-r2wd1yfa	211	10	via	via	IN
cord-015935-r2wd1yfa	211	11	linkage	linkage	NN
cord-015935-r2wd1yfa	211	12	studies	study	NNS
cord-015935-r2wd1yfa	211	13	,	,	,
cord-015935-r2wd1yfa	211	14	narrows	narrow	VBZ
cord-015935-r2wd1yfa	211	15	the	the	DT
cord-015935-r2wd1yfa	211	16	scope	scope	NN
cord-015935-r2wd1yfa	211	17	of	of	IN
cord-015935-r2wd1yfa	211	18	analysis	analysis	NN
cord-015935-r2wd1yfa	211	19	(	(	-LRB-
cord-015935-r2wd1yfa	211	20	Losh	Losh	NNP
cord-015935-r2wd1yfa	211	21	et	et	NNP
cord-015935-r2wd1yfa	211	22	al	al	NNP
cord-015935-r2wd1yfa	211	23	.	.	.
cord-015935-r2wd1yfa	212	1	,	,	,
cord-015935-r2wd1yfa	212	2	2008	2008	CD
cord-015935-r2wd1yfa	212	3	;	;	:
cord-015935-r2wd1yfa	212	4	O'Roak	O'Roak	NNP
cord-015935-r2wd1yfa	212	5	&	&	CC
cord-015935-r2wd1yfa	212	6	State	State	NNP
cord-015935-r2wd1yfa	212	7	,	,	,
cord-015935-r2wd1yfa	212	8	2008	2008	CD
cord-015935-r2wd1yfa	212	9	)	)	-RRB-
cord-015935-r2wd1yfa	212	10	.	.	.
cord-015935-r2wd1yfa	213	1	Reports	report	NNS
cord-015935-r2wd1yfa	213	2	of	of	IN
cord-015935-r2wd1yfa	213	3	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	213	4	abnormalities	abnormality	NNS
cord-015935-r2wd1yfa	213	5	detected	detect	VBN
cord-015935-r2wd1yfa	213	6	by	by	IN
cord-015935-r2wd1yfa	213	7	karyotyping	karyotype	VBG
cord-015935-r2wd1yfa	213	8	first	first	RB
cord-015935-r2wd1yfa	213	9	demonstrated	demonstrate	VBD
cord-015935-r2wd1yfa	213	10	that	that	IN
cord-015935-r2wd1yfa	213	11	rare	rare	JJ
cord-015935-r2wd1yfa	213	12	variants	variant	NNS
cord-015935-r2wd1yfa	213	13	may	may	MD
cord-015935-r2wd1yfa	213	14	contribute	contribute	VB
cord-015935-r2wd1yfa	213	15	to	to	IN
cord-015935-r2wd1yfa	213	16	autism	autism	NN
cord-015935-r2wd1yfa	213	17	(	(	-LRB-
cord-015935-r2wd1yfa	213	18	Vorstman	Vorstman	NNP
cord-015935-r2wd1yfa	213	19	et	et	NNP
cord-015935-r2wd1yfa	213	20	al	al	NNP
cord-015935-r2wd1yfa	213	21	.	.	NNP
cord-015935-r2wd1yfa	213	22	,	,	,
cord-015935-r2wd1yfa	213	23	2006	2006	CD
cord-015935-r2wd1yfa	213	24	)	)	-RRB-
cord-015935-r2wd1yfa	213	25	.	.	.
cord-015935-r2wd1yfa	214	1	Estimates	estimate	NNS
cord-015935-r2wd1yfa	214	2	of	of	IN
cord-015935-r2wd1yfa	214	3	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	214	4	abnormalities	abnormality	NNS
cord-015935-r2wd1yfa	214	5	in	in	IN
cord-015935-r2wd1yfa	214	6	autism	autism	NN
cord-015935-r2wd1yfa	214	7	range	range	NN
cord-015935-r2wd1yfa	214	8	from	from	IN
cord-015935-r2wd1yfa	214	9	6	6	CD
cord-015935-r2wd1yfa	214	10	to	to	TO
cord-015935-r2wd1yfa	214	11	40	40	CD
cord-015935-r2wd1yfa	214	12	%	%	NN
cord-015935-r2wd1yfa	214	13	(	(	-LRB-
cord-015935-r2wd1yfa	214	14	Abrahams	Abrahams	NNP
cord-015935-r2wd1yfa	214	15	&	&	CC
cord-015935-r2wd1yfa	214	16	Geschwind	Geschwind	NNP
cord-015935-r2wd1yfa	214	17	,	,	,
cord-015935-r2wd1yfa	214	18	2008	2008	CD
cord-015935-r2wd1yfa	214	19	;	;	.
cord-015935-r2wd1yfa	215	1	Marshall	Marshall	NNP
cord-015935-r2wd1yfa	215	2	et	et	NNP
cord-015935-r2wd1yfa	215	3	al	al	NNP
cord-015935-r2wd1yfa	215	4	.	.	NNP
cord-015935-r2wd1yfa	215	5	,	,	,
cord-015935-r2wd1yfa	215	6	2008	2008	CD
cord-015935-r2wd1yfa	215	7	;	;	:
cord-015935-r2wd1yfa	215	8	Pennington	Pennington	NNP
cord-015935-r2wd1yfa	215	9	,	,	,
cord-015935-r2wd1yfa	215	10	2009	2009	CD
cord-015935-r2wd1yfa	215	11	;	;	:
cord-015935-r2wd1yfa	215	12	Schaefer	Schaefer	NNP
cord-015935-r2wd1yfa	215	13	&	&	CC
cord-015935-r2wd1yfa	215	14	Lutz	Lutz	NNP
cord-015935-r2wd1yfa	215	15	,	,	,
cord-015935-r2wd1yfa	215	16	2006	2006	CD
cord-015935-r2wd1yfa	215	17	)	)	-RRB-
cord-015935-r2wd1yfa	216	1	so	so	IN
cord-015935-r2wd1yfa	216	2	that	that	IN
cord-015935-r2wd1yfa	216	3	genetic	genetic	JJ
cord-015935-r2wd1yfa	216	4	workup	workup	NN
cord-015935-r2wd1yfa	216	5	is	be	VBZ
cord-015935-r2wd1yfa	216	6	now	now	RB
cord-015935-r2wd1yfa	216	7	being	be	VBG
cord-015935-r2wd1yfa	216	8	recommended	recommend	VBN
cord-015935-r2wd1yfa	216	9	for	for	IN
cord-015935-r2wd1yfa	216	10	all	all	DT
cord-015935-r2wd1yfa	216	11	children	child	NNS
cord-015935-r2wd1yfa	216	12	diagnosed	diagnose	VBN
cord-015935-r2wd1yfa	216	13	with	with	IN
cord-015935-r2wd1yfa	216	14	autism	autism	NN
cord-015935-r2wd1yfa	216	15	(	(	-LRB-
cord-015935-r2wd1yfa	216	16	Pennington	Pennington	NNP
cord-015935-r2wd1yfa	216	17	,	,	,
cord-015935-r2wd1yfa	216	18	2009	2009	CD
cord-015935-r2wd1yfa	216	19	;	;	:
cord-015935-r2wd1yfa	216	20	.	.	.
cord-015935-r2wd1yfa	217	1	Chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	217	2	studies	study	NNS
cord-015935-r2wd1yfa	217	3	have	have	VBP
cord-015935-r2wd1yfa	217	4	produced	produce	VBN
cord-015935-r2wd1yfa	217	5	a	a	DT
cord-015935-r2wd1yfa	217	6	great	great	JJ
cord-015935-r2wd1yfa	217	7	interest	interest	NN
cord-015935-r2wd1yfa	217	8	in	in	IN
cord-015935-r2wd1yfa	217	9	chromosome	chromosome	NN
cord-015935-r2wd1yfa	217	10	15q11	15q11	CD
cord-015935-r2wd1yfa	217	11	-	-	SYM
cord-015935-r2wd1yfa	217	12	13	13	CD
cord-015935-r2wd1yfa	217	13	,	,	,
cord-015935-r2wd1yfa	217	14	the	the	DT
cord-015935-r2wd1yfa	217	15	site	site	NN
cord-015935-r2wd1yfa	217	16	of	of	IN
cord-015935-r2wd1yfa	217	17	the	the	DT
cord-015935-r2wd1yfa	217	18	most	most	RBS
cord-015935-r2wd1yfa	217	19	frequent	frequent	JJ
cord-015935-r2wd1yfa	217	20	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	217	21	anomaly	anomaly	NN
cord-015935-r2wd1yfa	217	22	seen	see	VBN
cord-015935-r2wd1yfa	217	23	in	in	IN
cord-015935-r2wd1yfa	217	24	autism	autism	NN
cord-015935-r2wd1yfa	217	25	(	(	-LRB-
cord-015935-r2wd1yfa	217	26	reviewed	review	VBN
cord-015935-r2wd1yfa	217	27	in	in	IN
cord-015935-r2wd1yfa	217	28	Veenstra	Veenstra	NNP
cord-015935-r2wd1yfa	217	29	-	-	HYPH
cord-015935-r2wd1yfa	217	30	VanderWeele	VanderWeele	NNP
cord-015935-r2wd1yfa	217	31	&	&	CC
cord-015935-r2wd1yfa	217	32	Cook	Cook	NNP
cord-015935-r2wd1yfa	217	33	,	,	,
cord-015935-r2wd1yfa	217	34	2004	2004	CD
cord-015935-r2wd1yfa	217	35	)	)	-RRB-
cord-015935-r2wd1yfa	217	36	.	.	.
cord-015935-r2wd1yfa	218	1	The	the	DT
cord-015935-r2wd1yfa	218	2	maternally	maternally	RB
cord-015935-r2wd1yfa	218	3	derived	derive	VBN
cord-015935-r2wd1yfa	218	4	duplication	duplication	NN
cord-015935-r2wd1yfa	218	5	of	of	IN
cord-015935-r2wd1yfa	218	6	this	this	DT
cord-015935-r2wd1yfa	218	7	region	region	NN
cord-015935-r2wd1yfa	218	8	involves	involve	VBZ
cord-015935-r2wd1yfa	218	9	an	an	DT
cord-015935-r2wd1yfa	218	10	imprinting	imprinting	NN
cord-015935-r2wd1yfa	218	11	mechanism	mechanism	NN
cord-015935-r2wd1yfa	218	12	.	.	.
cord-015935-r2wd1yfa	219	1	Maternal	maternal	JJ
cord-015935-r2wd1yfa	219	2	interstitial	interstitial	JJ
cord-015935-r2wd1yfa	219	3	duplication	duplication	NN
cord-015935-r2wd1yfa	219	4	or	or	CC
cord-015935-r2wd1yfa	219	5	supernumerary	supernumerary	JJ
cord-015935-r2wd1yfa	219	6	inverted	inverted	JJ
cord-015935-r2wd1yfa	219	7	duplication	duplication	NN
cord-015935-r2wd1yfa	219	8	of	of	IN
cord-015935-r2wd1yfa	219	9	15q11	15q11	CD
cord-015935-r2wd1yfa	219	10	-	-	SYM
cord-015935-r2wd1yfa	219	11	13	13	CD
cord-015935-r2wd1yfa	219	12	is	be	VBZ
cord-015935-r2wd1yfa	219	13	seen	see	VBN
cord-015935-r2wd1yfa	219	14	in	in	IN
cord-015935-r2wd1yfa	219	15	1	1	CD
cord-015935-r2wd1yfa	219	16	-	-	SYM
cord-015935-r2wd1yfa	219	17	3	3	CD
cord-015935-r2wd1yfa	219	18	%	%	NN
cord-015935-r2wd1yfa	219	19	of	of	IN
cord-015935-r2wd1yfa	219	20	patients	patient	NNS
cord-015935-r2wd1yfa	219	21	(	(	-LRB-
cord-015935-r2wd1yfa	219	22	Cook	Cook	NNP
cord-015935-r2wd1yfa	219	23	et	et	NNP
cord-015935-r2wd1yfa	219	24	al	al	NNP
cord-015935-r2wd1yfa	219	25	.	.	.
cord-015935-r2wd1yfa	220	1	,	,	,
cord-015935-r2wd1yfa	220	2	1990	1990	CD
cord-015935-r2wd1yfa	220	3	;	;	:
cord-015935-r2wd1yfa	220	4	Schroer	Schroer	NNP
cord-015935-r2wd1yfa	220	5	et	et	NNP
cord-015935-r2wd1yfa	220	6	al	al	NNP
cord-015935-r2wd1yfa	220	7	.	.	NNP
cord-015935-r2wd1yfa	220	8	,	,	,
cord-015935-r2wd1yfa	220	9	1998	1998	CD
cord-015935-r2wd1yfa	220	10	)	)	-RRB-
cord-015935-r2wd1yfa	220	11	.	.	.
cord-015935-r2wd1yfa	221	1	Clinical	clinical	JJ
cord-015935-r2wd1yfa	221	2	features	feature	NNS
cord-015935-r2wd1yfa	221	3	of	of	IN
cord-015935-r2wd1yfa	221	4	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	221	5	derangement	derangement	NN
cord-015935-r2wd1yfa	221	6	in	in	IN
cord-015935-r2wd1yfa	221	7	this	this	DT
cord-015935-r2wd1yfa	221	8	region	region	NN
cord-015935-r2wd1yfa	221	9	include	include	VBP
cord-015935-r2wd1yfa	221	10	mental	mental	JJ
cord-015935-r2wd1yfa	221	11	retardation	retardation	NN
cord-015935-r2wd1yfa	221	12	,	,	,
cord-015935-r2wd1yfa	221	13	motor	motor	NN
cord-015935-r2wd1yfa	221	14	impairment	impairment	NN
cord-015935-r2wd1yfa	221	15	,	,	,
cord-015935-r2wd1yfa	221	16	seizure	seizure	NN
cord-015935-r2wd1yfa	221	17	disorder	disorder	NN
cord-015935-r2wd1yfa	221	18	,	,	,
cord-015935-r2wd1yfa	221	19	and	and	CC
cord-015935-r2wd1yfa	221	20	impairment	impairment	NN
cord-015935-r2wd1yfa	221	21	in	in	IN
cord-015935-r2wd1yfa	221	22	communication	communication	NN
cord-015935-r2wd1yfa	221	23	,	,	,
cord-015935-r2wd1yfa	221	24	in	in	IN
cord-015935-r2wd1yfa	221	25	some	some	DT
cord-015935-r2wd1yfa	221	26	but	but	CC
cord-015935-r2wd1yfa	221	27	not	not	RB
cord-015935-r2wd1yfa	221	28	all	all	DT
cord-015935-r2wd1yfa	221	29	with	with	IN
cord-015935-r2wd1yfa	221	30	autism	autism	NN
cord-015935-r2wd1yfa	221	31	or	or	CC
cord-015935-r2wd1yfa	221	32	attentiondeficit	attentiondeficit	NNP
cord-015935-r2wd1yfa	221	33	hyperactivity	hyperactivity	NN
cord-015935-r2wd1yfa	221	34	disorder	disorder	NN
cord-015935-r2wd1yfa	221	35	(	(	-LRB-
cord-015935-r2wd1yfa	221	36	ADHD	ADHD	NNP
cord-015935-r2wd1yfa	221	37	;	;	:
cord-015935-r2wd1yfa	221	38	Cook	Cook	NNP
cord-015935-r2wd1yfa	221	39	et	et	NNP
cord-015935-r2wd1yfa	221	40	al	al	NNP
cord-015935-r2wd1yfa	221	41	.	.	NNP
cord-015935-r2wd1yfa	221	42	,	,	,
cord-015935-r2wd1yfa	221	43	1997	1997	CD
cord-015935-r2wd1yfa	221	44	;	;	:
cord-015935-r2wd1yfa	221	45	Schroer	Schroer	NNP
cord-015935-r2wd1yfa	221	46	et	et	NNP
cord-015935-r2wd1yfa	221	47	al	al	NNP
cord-015935-r2wd1yfa	221	48	.	.	NNP
cord-015935-r2wd1yfa	221	49	,	,	,
cord-015935-r2wd1yfa	221	50	1998	1998	CD
cord-015935-r2wd1yfa	221	51	)	)	-RRB-
cord-015935-r2wd1yfa	221	52	.	.	.
cord-015935-r2wd1yfa	222	1	The	the	DT
cord-015935-r2wd1yfa	222	2	duplication	duplication	NN
cord-015935-r2wd1yfa	222	3	of	of	IN
cord-015935-r2wd1yfa	222	4	15q11	15q11	CD
cord-015935-r2wd1yfa	222	5	-	-	SYM
cord-015935-r2wd1yfa	222	6	13	13	CD
cord-015935-r2wd1yfa	222	7	seen	see	VBN
cord-015935-r2wd1yfa	222	8	in	in	IN
cord-015935-r2wd1yfa	222	9	some	some	DT
cord-015935-r2wd1yfa	222	10	cases	case	NNS
cord-015935-r2wd1yfa	222	11	of	of	IN
cord-015935-r2wd1yfa	222	12	autism	autism	NN
cord-015935-r2wd1yfa	222	13	is	be	VBZ
cord-015935-r2wd1yfa	222	14	the	the	DT
cord-015935-r2wd1yfa	222	15	opposite	opposite	NN
cord-015935-r2wd1yfa	222	16	of	of	IN
cord-015935-r2wd1yfa	222	17	deletions	deletion	NNS
cord-015935-r2wd1yfa	222	18	from	from	IN
cord-015935-r2wd1yfa	222	19	the	the	DT
cord-015935-r2wd1yfa	222	20	same	same	JJ
cord-015935-r2wd1yfa	222	21	region	region	NN
cord-015935-r2wd1yfa	222	22	seen	see	VBN
cord-015935-r2wd1yfa	222	23	in	in	IN
cord-015935-r2wd1yfa	222	24	Angelman	Angelman	NNP
cord-015935-r2wd1yfa	222	25	's	's	POS
cord-015935-r2wd1yfa	222	26	syndrome	syndrome	NN
cord-015935-r2wd1yfa	222	27	(	(	-LRB-
cord-015935-r2wd1yfa	222	28	if	if	IN
cord-015935-r2wd1yfa	222	29	inherited	inherit	VBN
cord-015935-r2wd1yfa	222	30	from	from	IN
cord-015935-r2wd1yfa	222	31	the	the	DT
cord-015935-r2wd1yfa	222	32	mother	mother	NN
cord-015935-r2wd1yfa	222	33	)	)	-RRB-
cord-015935-r2wd1yfa	222	34	or	or	CC
cord-015935-r2wd1yfa	222	35	Prader	Prader	NNP
cord-015935-r2wd1yfa	222	36	Willi	Willi	NNP
cord-015935-r2wd1yfa	222	37	syndrome	syndrome	NN
cord-015935-r2wd1yfa	222	38	(	(	-LRB-
cord-015935-r2wd1yfa	222	39	if	if	IN
cord-015935-r2wd1yfa	222	40	inherited	inherit	VBN
cord-015935-r2wd1yfa	222	41	from	from	IN
cord-015935-r2wd1yfa	222	42	the	the	DT
cord-015935-r2wd1yfa	222	43	father	father	NN
cord-015935-r2wd1yfa	222	44	)	)	-RRB-
cord-015935-r2wd1yfa	222	45	.	.	.
cord-015935-r2wd1yfa	223	1	Angelman	Angelman	NNP
cord-015935-r2wd1yfa	223	2	's	's	POS
cord-015935-r2wd1yfa	223	3	syndrome	syndrome	NN
cord-015935-r2wd1yfa	223	4	,	,	,
cord-015935-r2wd1yfa	223	5	known	know	VBN
cord-015935-r2wd1yfa	223	6	as	as	IN
cord-015935-r2wd1yfa	223	7	the	the	DT
cord-015935-r2wd1yfa	223	8	"	"	``
cord-015935-r2wd1yfa	223	9	happy	happy	JJ
cord-015935-r2wd1yfa	223	10	puppet	puppet	NN
cord-015935-r2wd1yfa	223	11	"	"	''
cord-015935-r2wd1yfa	223	12	phenotype	phenotype	NN
cord-015935-r2wd1yfa	223	13	,	,	,
cord-015935-r2wd1yfa	223	14	involves	involve	VBZ
cord-015935-r2wd1yfa	223	15	mental	mental	JJ
cord-015935-r2wd1yfa	223	16	retardation	retardation	NN
cord-015935-r2wd1yfa	223	17	,	,	,
cord-015935-r2wd1yfa	223	18	epilepsy	epilepsy	NN
cord-015935-r2wd1yfa	223	19	,	,	,
cord-015935-r2wd1yfa	223	20	ataxia	ataxia	NN
cord-015935-r2wd1yfa	223	21	,	,	,
cord-015935-r2wd1yfa	223	22	lack	lack	NN
cord-015935-r2wd1yfa	223	23	of	of	IN
cord-015935-r2wd1yfa	223	24	speech	speech	NN
cord-015935-r2wd1yfa	223	25	,	,	,
cord-015935-r2wd1yfa	223	26	predominant	predominant	JJ
cord-015935-r2wd1yfa	223	27	laughing	laugh	VBG
cord-015935-r2wd1yfa	223	28	and	and	CC
cord-015935-r2wd1yfa	223	29	smiling	smile	VBG
cord-015935-r2wd1yfa	223	30	,	,	,
cord-015935-r2wd1yfa	223	31	and	and	CC
cord-015935-r2wd1yfa	223	32	a	a	DT
cord-015935-r2wd1yfa	223	33	high	high	JJ
cord-015935-r2wd1yfa	223	34	rate	rate	NN
cord-015935-r2wd1yfa	223	35	of	of	IN
cord-015935-r2wd1yfa	223	36	autism	autism	NN
cord-015935-r2wd1yfa	223	37	.	.	.
cord-015935-r2wd1yfa	224	1	Prader	Prader	NNP
cord-015935-r2wd1yfa	224	2	Willi	Willi	NNP
cord-015935-r2wd1yfa	224	3	syndrome	syndrome	NN
cord-015935-r2wd1yfa	224	4	associated	associate	VBN
cord-015935-r2wd1yfa	224	5	with	with	IN
cord-015935-r2wd1yfa	224	6	mental	mental	JJ
cord-015935-r2wd1yfa	224	7	retardation	retardation	NN
cord-015935-r2wd1yfa	224	8	and	and	CC
cord-015935-r2wd1yfa	224	9	hyperphagia	hyperphagia	NNP
cord-015935-r2wd1yfa	224	10	is	be	VBZ
cord-015935-r2wd1yfa	224	11	only	only	RB
cord-015935-r2wd1yfa	224	12	occasionally	occasionally	RB
cord-015935-r2wd1yfa	224	13	associated	associate	VBN
cord-015935-r2wd1yfa	224	14	with	with	IN
cord-015935-r2wd1yfa	224	15	autism	autism	NN
cord-015935-r2wd1yfa	224	16	.	.	.
cord-015935-r2wd1yfa	225	1	Presently	presently	RB
cord-015935-r2wd1yfa	225	2	,	,	,
cord-015935-r2wd1yfa	225	3	there	there	EX
cord-015935-r2wd1yfa	225	4	is	be	VBZ
cord-015935-r2wd1yfa	225	5	ongoing	ongoing	JJ
cord-015935-r2wd1yfa	225	6	research	research	NN
cord-015935-r2wd1yfa	225	7	regarding	regard	VBG
cord-015935-r2wd1yfa	225	8	how	how	WRB
cord-015935-r2wd1yfa	225	9	duplications	duplication	NNS
cord-015935-r2wd1yfa	225	10	and	and	CC
cord-015935-r2wd1yfa	225	11	deletions	deletion	NNS
cord-015935-r2wd1yfa	225	12	in	in	IN
cord-015935-r2wd1yfa	225	13	this	this	DT
cord-015935-r2wd1yfa	225	14	gene	gene	NN
cord-015935-r2wd1yfa	225	15	region	region	NN
cord-015935-r2wd1yfa	225	16	lead	lead	VBP
cord-015935-r2wd1yfa	225	17	to	to	IN
cord-015935-r2wd1yfa	225	18	an	an	DT
cord-015935-r2wd1yfa	225	19	increased	increase	VBN
cord-015935-r2wd1yfa	225	20	risk	risk	NN
cord-015935-r2wd1yfa	225	21	of	of	IN
cord-015935-r2wd1yfa	225	22	autism	autism	NN
cord-015935-r2wd1yfa	225	23	(	(	-LRB-
cord-015935-r2wd1yfa	225	24	Veenstra	Veenstra	NNP
cord-015935-r2wd1yfa	225	25	-	-	HYPH
cord-015935-r2wd1yfa	225	26	VanderWeele	VanderWeele	NNP
cord-015935-r2wd1yfa	225	27	&	&	CC
cord-015935-r2wd1yfa	225	28	Cook	Cook	NNP
cord-015935-r2wd1yfa	225	29	,	,	,
cord-015935-r2wd1yfa	225	30	2004	2004	CD
cord-015935-r2wd1yfa	225	31	)	)	-RRB-
cord-015935-r2wd1yfa	225	32	.	.	.
cord-015935-r2wd1yfa	226	1	This	this	DT
cord-015935-r2wd1yfa	226	2	region	region	NN
cord-015935-r2wd1yfa	226	3	,	,	,
cord-015935-r2wd1yfa	226	4	however	however	RB
cord-015935-r2wd1yfa	226	5	,	,	,
cord-015935-r2wd1yfa	226	6	has	have	VBZ
cord-015935-r2wd1yfa	226	7	not	not	RB
cord-015935-r2wd1yfa	226	8	been	be	VBN
cord-015935-r2wd1yfa	226	9	identified	identify	VBN
cord-015935-r2wd1yfa	226	10	as	as	IN
cord-015935-r2wd1yfa	226	11	one	one	CD
cord-015935-r2wd1yfa	226	12	of	of	IN
cord-015935-r2wd1yfa	226	13	interest	interest	NN
cord-015935-r2wd1yfa	226	14	in	in	IN
cord-015935-r2wd1yfa	226	15	whole	whole	JJ
cord-015935-r2wd1yfa	226	16	genome	genome	NN
cord-015935-r2wd1yfa	226	17	searches	search	NNS
cord-015935-r2wd1yfa	226	18	,	,	,
cord-015935-r2wd1yfa	226	19	perhaps	perhaps	RB
cord-015935-r2wd1yfa	226	20	due	due	IN
cord-015935-r2wd1yfa	226	21	to	to	IN
cord-015935-r2wd1yfa	226	22	its	-PRON-	PRP$
cord-015935-r2wd1yfa	226	23	rarity	rarity	NN
cord-015935-r2wd1yfa	226	24	(	(	-LRB-
cord-015935-r2wd1yfa	226	25	Pennington	Pennington	NNP
cord-015935-r2wd1yfa	226	26	,	,	,
cord-015935-r2wd1yfa	226	27	2009	2009	CD
cord-015935-r2wd1yfa	226	28	)	)	-RRB-
cord-015935-r2wd1yfa	226	29	.	.	.
cord-015935-r2wd1yfa	227	1	Still	still	RB
cord-015935-r2wd1yfa	227	2	,	,	,
cord-015935-r2wd1yfa	227	3	FISH	fish	NN
cord-015935-r2wd1yfa	227	4	analysis	analysis	NN
cord-015935-r2wd1yfa	227	5	of	of	IN
cord-015935-r2wd1yfa	227	6	chromosome	chromosome	NN
cord-015935-r2wd1yfa	227	7	15q11	15q11	CD
cord-015935-r2wd1yfa	227	8	-	-	SYM
cord-015935-r2wd1yfa	227	9	13	13	CD
cord-015935-r2wd1yfa	227	10	is	be	VBZ
cord-015935-r2wd1yfa	227	11	often	often	RB
cord-015935-r2wd1yfa	227	12	performed	perform	VBN
cord-015935-r2wd1yfa	227	13	in	in	IN
cord-015935-r2wd1yfa	227	14	evaluation	evaluation	NN
cord-015935-r2wd1yfa	227	15	of	of	IN
cord-015935-r2wd1yfa	227	16	children	child	NNS
cord-015935-r2wd1yfa	227	17	with	with	IN
cord-015935-r2wd1yfa	227	18	autism	autism	NN
cord-015935-r2wd1yfa	227	19	.	.	.
cord-015935-r2wd1yfa	228	1	Recently	recently	RB
cord-015935-r2wd1yfa	228	2	,	,	,
cord-015935-r2wd1yfa	228	3	FISH	FISH	NNP
cord-015935-r2wd1yfa	228	4	is	be	VBZ
cord-015935-r2wd1yfa	228	5	being	be	VBG
cord-015935-r2wd1yfa	228	6	replaced	replace	VBN
cord-015935-r2wd1yfa	228	7	by	by	IN
cord-015935-r2wd1yfa	228	8	CGH	CGH	NNP
cord-015935-r2wd1yfa	228	9	due	due	JJ
cord-015935-r2wd1yfa	228	10	to	to	IN
cord-015935-r2wd1yfa	228	11	improved	improve	VBN
cord-015935-r2wd1yfa	228	12	detection	detection	NN
cord-015935-r2wd1yfa	228	13	of	of	IN
cord-015935-r2wd1yfa	228	14	abnormality	abnormality	NN
cord-015935-r2wd1yfa	228	15	within	within	IN
cord-015935-r2wd1yfa	228	16	the	the	DT
cord-015935-r2wd1yfa	228	17	15q11	15q11	CD
cord-015935-r2wd1yfa	228	18	-	-	SYM
cord-015935-r2wd1yfa	228	19	13	13	CD
cord-015935-r2wd1yfa	228	20	region	region	NN
cord-015935-r2wd1yfa	228	21	.	.	.
cord-015935-r2wd1yfa	229	1	Cytogenetic	cytogenetic	JJ
cord-015935-r2wd1yfa	229	2	approaches	approach	NNS
cord-015935-r2wd1yfa	229	3	provided	provide	VBD
cord-015935-r2wd1yfa	229	4	the	the	DT
cord-015935-r2wd1yfa	229	5	first	first	JJ
cord-015935-r2wd1yfa	229	6	evidence	evidence	NN
cord-015935-r2wd1yfa	229	7	for	for	IN
cord-015935-r2wd1yfa	229	8	an	an	DT
cord-015935-r2wd1yfa	229	9	autism	autism	NN
cord-015935-r2wd1yfa	229	10	gene	gene	NN
cord-015935-r2wd1yfa	229	11	40	40	CD
cord-015935-r2wd1yfa	229	12	years	year	NNS
cord-015935-r2wd1yfa	229	13	ago	ago	RB
cord-015935-r2wd1yfa	229	14	when	when	WRB
cord-015935-r2wd1yfa	229	15	Lubs	Lubs	NNP
cord-015935-r2wd1yfa	229	16	(	(	-LRB-
cord-015935-r2wd1yfa	229	17	1969	1969	CD
cord-015935-r2wd1yfa	229	18	)	)	-RRB-
cord-015935-r2wd1yfa	229	19	identified	identify	VBD
cord-015935-r2wd1yfa	229	20	an	an	DT
cord-015935-r2wd1yfa	229	21	abnormal	abnormal	JJ
cord-015935-r2wd1yfa	229	22	or	or	CC
cord-015935-r2wd1yfa	229	23	"	"	``
cord-015935-r2wd1yfa	229	24	fragile	fragile	JJ
cord-015935-r2wd1yfa	229	25	"	"	''
cord-015935-r2wd1yfa	229	26	site	site	NN
cord-015935-r2wd1yfa	229	27	on	on	IN
cord-015935-r2wd1yfa	229	28	the	the	DT
cord-015935-r2wd1yfa	229	29	long	long	JJ
cord-015935-r2wd1yfa	229	30	arm	arm	NN
cord-015935-r2wd1yfa	229	31	of	of	IN
cord-015935-r2wd1yfa	229	32	chromosome	chromosome	NN
cord-015935-r2wd1yfa	229	33	X	x	NN
cord-015935-r2wd1yfa	229	34	in	in	IN
cord-015935-r2wd1yfa	229	35	four	four	CD
cord-015935-r2wd1yfa	229	36	males	male	NNS
cord-015935-r2wd1yfa	229	37	with	with	IN
cord-015935-r2wd1yfa	229	38	mental	mental	JJ
cord-015935-r2wd1yfa	229	39	retardation	retardation	NN
cord-015935-r2wd1yfa	229	40	,	,	,
cord-015935-r2wd1yfa	229	41	leading	lead	VBG
cord-015935-r2wd1yfa	229	42	to	to	IN
cord-015935-r2wd1yfa	229	43	the	the	DT
cord-015935-r2wd1yfa	229	44	recognition	recognition	NN
cord-015935-r2wd1yfa	229	45	of	of	IN
cord-015935-r2wd1yfa	229	46	fragile	fragile	JJ
cord-015935-r2wd1yfa	229	47	X	x	NN
cord-015935-r2wd1yfa	229	48	syndrome	syndrome	NN
cord-015935-r2wd1yfa	229	49	(	(	-LRB-
cord-015935-r2wd1yfa	229	50	FXS	FXS	NNP
cord-015935-r2wd1yfa	229	51	)	)	-RRB-
cord-015935-r2wd1yfa	229	52	.	.	.
cord-015935-r2wd1yfa	230	1	This	this	DT
cord-015935-r2wd1yfa	230	2	syndrome	syndrome	NN
cord-015935-r2wd1yfa	230	3	,	,	,
cord-015935-r2wd1yfa	230	4	associated	associate	VBN
cord-015935-r2wd1yfa	230	5	with	with	IN
cord-015935-r2wd1yfa	230	6	mental	mental	JJ
cord-015935-r2wd1yfa	230	7	retardation	retardation	NN
cord-015935-r2wd1yfa	230	8	and	and	CC
cord-015935-r2wd1yfa	230	9	autistic	autistic	JJ
cord-015935-r2wd1yfa	230	10	features	feature	NNS
cord-015935-r2wd1yfa	230	11	,	,	,
cord-015935-r2wd1yfa	230	12	is	be	VBZ
cord-015935-r2wd1yfa	230	13	more	more	RBR
cord-015935-r2wd1yfa	230	14	severely	severely	RB
cord-015935-r2wd1yfa	230	15	expressed	express	VBN
cord-015935-r2wd1yfa	230	16	in	in	IN
cord-015935-r2wd1yfa	230	17	males	male	NNS
cord-015935-r2wd1yfa	230	18	.	.	.
cord-015935-r2wd1yfa	231	1	FXS	FXS	NNP
cord-015935-r2wd1yfa	231	2	is	be	VBZ
cord-015935-r2wd1yfa	231	3	caused	cause	VBN
cord-015935-r2wd1yfa	231	4	by	by	IN
cord-015935-r2wd1yfa	231	5	a	a	DT
cord-015935-r2wd1yfa	231	6	deficiency	deficiency	NN
cord-015935-r2wd1yfa	231	7	of	of	IN
cord-015935-r2wd1yfa	231	8	the	the	DT
cord-015935-r2wd1yfa	231	9	fragile	fragile	JJ
cord-015935-r2wd1yfa	231	10	X	x	NN
cord-015935-r2wd1yfa	231	11	mental	mental	JJ
cord-015935-r2wd1yfa	231	12	retardation	retardation	NN
cord-015935-r2wd1yfa	231	13	protein	protein	NN
cord-015935-r2wd1yfa	231	14	(	(	-LRB-
cord-015935-r2wd1yfa	231	15	FMRP	FMRP	NNP
cord-015935-r2wd1yfa	231	16	)	)	-RRB-
cord-015935-r2wd1yfa	231	17	,	,	,
cord-015935-r2wd1yfa	231	18	resulting	result	VBG
cord-015935-r2wd1yfa	231	19	from	from	IN
cord-015935-r2wd1yfa	231	20	little	little	JJ
cord-015935-r2wd1yfa	231	21	or	or	CC
cord-015935-r2wd1yfa	231	22	none	none	NN
cord-015935-r2wd1yfa	231	23	of	of	IN
cord-015935-r2wd1yfa	231	24	the	the	DT
cord-015935-r2wd1yfa	231	25	disease	disease	NN
cord-015935-r2wd1yfa	231	26	gene	gene	NN
cord-015935-r2wd1yfa	231	27	fragile	fragile	NNP
cord-015935-r2wd1yfa	231	28	X	x	CD
cord-015935-r2wd1yfa	231	29	mental	mental	JJ
cord-015935-r2wd1yfa	231	30	retardation	retardation	NN
cord-015935-r2wd1yfa	231	31	1	1	CD
cord-015935-r2wd1yfa	232	1	(	(	-LRB-
cord-015935-r2wd1yfa	232	2	FMR1	FMR1	NNP
cord-015935-r2wd1yfa	232	3	)	)	-RRB-
cord-015935-r2wd1yfa	233	1	mRNA	mRNA	NNP
cord-015935-r2wd1yfa	233	2	.	.	.
cord-015935-r2wd1yfa	234	1	The	the	DT
cord-015935-r2wd1yfa	234	2	FMR1	FMR1	NNP
cord-015935-r2wd1yfa	234	3	gene	gene	NN
cord-015935-r2wd1yfa	234	4	mutation	mutation	NN
cord-015935-r2wd1yfa	234	5	consisting	consist	VBG
cord-015935-r2wd1yfa	234	6	of	of	IN
cord-015935-r2wd1yfa	234	7	expanded	expand	VBN
cord-015935-r2wd1yfa	234	8	CGG	CGG	NNP
cord-015935-r2wd1yfa	234	9	repeats	repeat	VBZ
cord-015935-r2wd1yfa	234	10	of	of	IN
cord-015935-r2wd1yfa	234	11	>	>	$
cord-015935-r2wd1yfa	234	12	200	200	CD
cord-015935-r2wd1yfa	234	13	at	at	IN
cord-015935-r2wd1yfa	234	14	chromosome	chromosome	NN
cord-015935-r2wd1yfa	234	15	site	site	NN
cord-015935-r2wd1yfa	235	1	Xq27.3	Xq27.3	NNP
cord-015935-r2wd1yfa	235	2	is	be	VBZ
cord-015935-r2wd1yfa	235	3	considered	consider	VBN
cord-015935-r2wd1yfa	235	4	the	the	DT
cord-015935-r2wd1yfa	235	5	origin	origin	NN
cord-015935-r2wd1yfa	235	6	of	of	IN
cord-015935-r2wd1yfa	235	7	FXS	FXS	NNP
cord-015935-r2wd1yfa	235	8	.	.	.
cord-015935-r2wd1yfa	236	1	Autism	Autism	NNP
cord-015935-r2wd1yfa	236	2	,	,	,
cord-015935-r2wd1yfa	236	3	using	use	VBG
cord-015935-r2wd1yfa	236	4	the	the	DT
cord-015935-r2wd1yfa	236	5	broad	broad	JJ
cord-015935-r2wd1yfa	236	6	definition	definition	NN
cord-015935-r2wd1yfa	236	7	,	,	,
cord-015935-r2wd1yfa	236	8	has	have	VBZ
cord-015935-r2wd1yfa	236	9	been	be	VBN
cord-015935-r2wd1yfa	236	10	reported	report	VBN
cord-015935-r2wd1yfa	236	11	in	in	IN
cord-015935-r2wd1yfa	236	12	up	up	IN
cord-015935-r2wd1yfa	236	13	to	to	TO
cord-015935-r2wd1yfa	236	14	30	30	CD
cord-015935-r2wd1yfa	236	15	%	%	NN
cord-015935-r2wd1yfa	236	16	of	of	IN
cord-015935-r2wd1yfa	236	17	males	male	NNS
cord-015935-r2wd1yfa	236	18	with	with	IN
cord-015935-r2wd1yfa	236	19	FXS	FXS	NNP
cord-015935-r2wd1yfa	236	20	,	,	,
cord-015935-r2wd1yfa	236	21	and	and	CC
cord-015935-r2wd1yfa	236	22	FXS	FXS	NNP
cord-015935-r2wd1yfa	236	23	can	can	MD
cord-015935-r2wd1yfa	236	24	be	be	VB
cord-015935-r2wd1yfa	236	25	found	find	VBN
cord-015935-r2wd1yfa	236	26	in	in	IN
cord-015935-r2wd1yfa	236	27	as	as	RB
cord-015935-r2wd1yfa	236	28	many	many	JJ
cord-015935-r2wd1yfa	236	29	as	as	IN
cord-015935-r2wd1yfa	236	30	7	7	CD
cord-015935-r2wd1yfa	236	31	-	-	SYM
cord-015935-r2wd1yfa	236	32	8	8	CD
cord-015935-r2wd1yfa	236	33	%	%	NN
cord-015935-r2wd1yfa	236	34	of	of	IN
cord-015935-r2wd1yfa	236	35	individuals	individual	NNS
cord-015935-r2wd1yfa	236	36	with	with	IN
cord-015935-r2wd1yfa	236	37	autism	autism	NN
cord-015935-r2wd1yfa	236	38	(	(	-LRB-
cord-015935-r2wd1yfa	236	39	Muhle	Muhle	NNP
cord-015935-r2wd1yfa	236	40	,	,	,
cord-015935-r2wd1yfa	236	41	Trentacoste	Trentacoste	NNP
cord-015935-r2wd1yfa	236	42	,	,	,
cord-015935-r2wd1yfa	236	43	&	&	CC
cord-015935-r2wd1yfa	236	44	Rapin	Rapin	NNP
cord-015935-r2wd1yfa	236	45	,	,	,
cord-015935-r2wd1yfa	236	46	2004	2004	CD
cord-015935-r2wd1yfa	236	47	)	)	-RRB-
cord-015935-r2wd1yfa	236	48	.	.	.
cord-015935-r2wd1yfa	237	1	Later	later	JJ
cord-015935-r2wd1yfa	237	2	studies	study	NNS
cord-015935-r2wd1yfa	237	3	,	,	,
cord-015935-r2wd1yfa	237	4	using	use	VBG
cord-015935-r2wd1yfa	237	5	DNA	dna	NN
cord-015935-r2wd1yfa	237	6	measures	measure	NNS
cord-015935-r2wd1yfa	237	7	of	of	IN
cord-015935-r2wd1yfa	237	8	the	the	DT
cord-015935-r2wd1yfa	237	9	fragile	fragile	JJ
cord-015935-r2wd1yfa	237	10	X	x	NN
cord-015935-r2wd1yfa	237	11	mutation	mutation	NN
cord-015935-r2wd1yfa	237	12	rather	rather	RB
cord-015935-r2wd1yfa	237	13	than	than	IN
cord-015935-r2wd1yfa	237	14	cytogenetics	cytogenetic	NNS
cord-015935-r2wd1yfa	237	15	and	and	CC
cord-015935-r2wd1yfa	237	16	strict	strict	JJ
cord-015935-r2wd1yfa	237	17	autism	autism	NN
cord-015935-r2wd1yfa	237	18	criteria	criterion	NNS
cord-015935-r2wd1yfa	237	19	,	,	,
cord-015935-r2wd1yfa	237	20	have	have	VBP
cord-015935-r2wd1yfa	237	21	found	find	VBN
cord-015935-r2wd1yfa	237	22	a	a	DT
cord-015935-r2wd1yfa	237	23	smaller	small	JJR
cord-015935-r2wd1yfa	237	24	association	association	NN
cord-015935-r2wd1yfa	237	25	between	between	IN
cord-015935-r2wd1yfa	237	26	FXS	FXS	NNP
cord-015935-r2wd1yfa	237	27	and	and	CC
cord-015935-r2wd1yfa	237	28	autism	autism	NN
cord-015935-r2wd1yfa	237	29	(	(	-LRB-
cord-015935-r2wd1yfa	237	30	Pennington	Pennington	NNP
cord-015935-r2wd1yfa	237	31	,	,	,
cord-015935-r2wd1yfa	237	32	2009	2009	CD
cord-015935-r2wd1yfa	237	33	)	)	-RRB-
cord-015935-r2wd1yfa	237	34	.	.	.
cord-015935-r2wd1yfa	238	1	Two	two	CD
cord-015935-r2wd1yfa	238	2	investigations	investigation	NNS
cord-015935-r2wd1yfa	238	3	,	,	,
cord-015935-r2wd1yfa	238	4	however	however	RB
cord-015935-r2wd1yfa	238	5	,	,	,
cord-015935-r2wd1yfa	238	6	which	which	WDT
cord-015935-r2wd1yfa	238	7	studied	study	VBD
cord-015935-r2wd1yfa	238	8	carefully	carefully	RB
cord-015935-r2wd1yfa	238	9	controlled	control	VBN
cord-015935-r2wd1yfa	238	10	groups	group	NNS
cord-015935-r2wd1yfa	238	11	of	of	IN
cord-015935-r2wd1yfa	238	12	FXS	FXS	NNP
cord-015935-r2wd1yfa	238	13	-	-	HYPH
cord-015935-r2wd1yfa	238	14	negative	negative	JJ
cord-015935-r2wd1yfa	238	15	and	and	CC
cord-015935-r2wd1yfa	238	16	FXS	FXS	NNP
cord-015935-r2wd1yfa	238	17	-	-	HYPH
cord-015935-r2wd1yfa	238	18	positive	positive	JJ
cord-015935-r2wd1yfa	238	19	males	male	NNS
cord-015935-r2wd1yfa	238	20	matched	match	VBN
cord-015935-r2wd1yfa	238	21	on	on	IN
cord-015935-r2wd1yfa	238	22	intelligence	intelligence	NN
cord-015935-r2wd1yfa	238	23	,	,	,
cord-015935-r2wd1yfa	238	24	found	find	VBD
cord-015935-r2wd1yfa	238	25	higher	high	JJR
cord-015935-r2wd1yfa	238	26	rates	rate	NNS
cord-015935-r2wd1yfa	238	27	of	of	IN
cord-015935-r2wd1yfa	238	28	the	the	DT
cord-015935-r2wd1yfa	238	29	following	follow	VBG
cord-015935-r2wd1yfa	238	30	autistic	autistic	JJ
cord-015935-r2wd1yfa	238	31	symptoms	symptom	NNS
cord-015935-r2wd1yfa	238	32	in	in	IN
cord-015935-r2wd1yfa	238	33	FXS	FXS	NNP
cord-015935-r2wd1yfa	238	34	males	male	NNS
cord-015935-r2wd1yfa	238	35	:	:	:
cord-015935-r2wd1yfa	238	36	gaze	gaze	NN
cord-015935-r2wd1yfa	238	37	avoidance	avoidance	NN
cord-015935-r2wd1yfa	238	38	and	and	CC
cord-015935-r2wd1yfa	238	39	hand	hand	NN
cord-015935-r2wd1yfa	238	40	flapping	flapping	NN
cord-015935-r2wd1yfa	238	41	(	(	-LRB-
cord-015935-r2wd1yfa	238	42	Einfeld	Einfeld	NNP
cord-015935-r2wd1yfa	238	43	,	,	,
cord-015935-r2wd1yfa	238	44	Molony	Molony	NNP
cord-015935-r2wd1yfa	238	45	,	,	,
cord-015935-r2wd1yfa	238	46	&	&	CC
cord-015935-r2wd1yfa	238	47	Hall	Hall	NNP
cord-015935-r2wd1yfa	238	48	,	,	,
cord-015935-r2wd1yfa	238	49	1989	1989	CD
cord-015935-r2wd1yfa	238	50	)	)	-RRB-
cord-015935-r2wd1yfa	238	51	and	and	CC
cord-015935-r2wd1yfa	238	52	stereotypic	stereotypic	JJ
cord-015935-r2wd1yfa	238	53	movements	movement	NNS
cord-015935-r2wd1yfa	238	54	(	(	-LRB-
cord-015935-r2wd1yfa	238	55	including	include	VBG
cord-015935-r2wd1yfa	238	56	hand	hand	NN
cord-015935-r2wd1yfa	238	57	flapping	flapping	NN
cord-015935-r2wd1yfa	238	58	,	,	,
cord-015935-r2wd1yfa	238	59	rocking	rock	VBG
cord-015935-r2wd1yfa	238	60	,	,	,
cord-015935-r2wd1yfa	238	61	and	and	CC
cord-015935-r2wd1yfa	238	62	hitting	hit	VBG
cord-015935-r2wd1yfa	238	63	,	,	,
cord-015935-r2wd1yfa	238	64	scratching	scratch	VBG
cord-015935-r2wd1yfa	238	65	,	,	,
cord-015935-r2wd1yfa	238	66	or	or	CC
cord-015935-r2wd1yfa	238	67	rubbing	rub	VBG
cord-015935-r2wd1yfa	238	68	their	-PRON-	PRP$
cord-015935-r2wd1yfa	238	69	own	own	JJ
cord-015935-r2wd1yfa	238	70	bodies	body	NNS
cord-015935-r2wd1yfa	238	71	)	)	-RRB-
cord-015935-r2wd1yfa	238	72	,	,	,
cord-015935-r2wd1yfa	238	73	echolalia	echolalia	NN
cord-015935-r2wd1yfa	238	74	,	,	,
cord-015935-r2wd1yfa	238	75	gaze	gaze	NN
cord-015935-r2wd1yfa	238	76	avoidance	avoidance	NN
cord-015935-r2wd1yfa	238	77	,	,	,
cord-015935-r2wd1yfa	238	78	and	and	CC
cord-015935-r2wd1yfa	238	79	ritualistic	ritualistic	JJ
cord-015935-r2wd1yfa	238	80	behaviors	behavior	NNS
cord-015935-r2wd1yfa	238	81	(	(	-LRB-
cord-015935-r2wd1yfa	238	82	Maes	Maes	NNP
cord-015935-r2wd1yfa	238	83	,	,	,
cord-015935-r2wd1yfa	238	84	Fryns	Fryns	NNP
cord-015935-r2wd1yfa	238	85	,	,	,
cord-015935-r2wd1yfa	238	86	Van	Van	NNP
cord-015935-r2wd1yfa	238	87	Walleghem	Walleghem	NNP
cord-015935-r2wd1yfa	238	88	,	,	,
cord-015935-r2wd1yfa	238	89	&	&	CC
cord-015935-r2wd1yfa	238	90	Van	Van	NNP
cord-015935-r2wd1yfa	238	91	den	den	NNP
cord-015935-r2wd1yfa	238	92	Berghe	Berghe	NNP
cord-015935-r2wd1yfa	238	93	,	,	,
cord-015935-r2wd1yfa	238	94	1993	1993	CD
cord-015935-r2wd1yfa	238	95	)	)	-RRB-
cord-015935-r2wd1yfa	238	96	.	.	.
cord-015935-r2wd1yfa	239	1	Studies	study	NNS
cord-015935-r2wd1yfa	239	2	of	of	IN
cord-015935-r2wd1yfa	239	3	endophenotype	endophenotype	NN
cord-015935-r2wd1yfa	239	4	behaviors	behavior	NNS
cord-015935-r2wd1yfa	239	5	rather	rather	RB
cord-015935-r2wd1yfa	239	6	than	than	IN
cord-015935-r2wd1yfa	239	7	the	the	DT
cord-015935-r2wd1yfa	239	8	strict	strict	JJ
cord-015935-r2wd1yfa	239	9	autism	autism	NN
cord-015935-r2wd1yfa	239	10	criteria	criterion	NNS
cord-015935-r2wd1yfa	239	11	are	be	VBP
cord-015935-r2wd1yfa	239	12	more	more	RBR
cord-015935-r2wd1yfa	239	13	likely	likely	JJ
cord-015935-r2wd1yfa	239	14	to	to	TO
cord-015935-r2wd1yfa	239	15	uncover	uncover	VB
cord-015935-r2wd1yfa	239	16	robust	robust	JJ
cord-015935-r2wd1yfa	239	17	similarities	similarity	NNS
cord-015935-r2wd1yfa	239	18	between	between	IN
cord-015935-r2wd1yfa	239	19	FXS	FXS	NNP
cord-015935-r2wd1yfa	239	20	and	and	CC
cord-015935-r2wd1yfa	239	21	autism	autism	NN
cord-015935-r2wd1yfa	239	22	.	.	.
cord-015935-r2wd1yfa	240	1	Exploring	explore	VBG
cord-015935-r2wd1yfa	240	2	similarities	similarity	NNS
cord-015935-r2wd1yfa	240	3	between	between	IN
cord-015935-r2wd1yfa	240	4	rare	rare	JJ
cord-015935-r2wd1yfa	240	5	sub	sub	NN
cord-015935-r2wd1yfa	240	6	-	-	NNS
cord-015935-r2wd1yfa	240	7	groups	group	NNS
cord-015935-r2wd1yfa	240	8	of	of	IN
cord-015935-r2wd1yfa	240	9	patients	patient	NNS
cord-015935-r2wd1yfa	240	10	with	with	IN
cord-015935-r2wd1yfa	240	11	a	a	DT
cord-015935-r2wd1yfa	240	12	known	know	VBN
cord-015935-r2wd1yfa	240	13	disorder	disorder	NN
cord-015935-r2wd1yfa	240	14	and	and	CC
cord-015935-r2wd1yfa	240	15	those	those	DT
cord-015935-r2wd1yfa	240	16	with	with	IN
cord-015935-r2wd1yfa	240	17	a	a	DT
cord-015935-r2wd1yfa	240	18	more	more	RBR
cord-015935-r2wd1yfa	240	19	common	common	JJ
cord-015935-r2wd1yfa	240	20	disorder	disorder	NN
cord-015935-r2wd1yfa	240	21	(	(	-LRB-
cord-015935-r2wd1yfa	240	22	autism	autism	NN
cord-015935-r2wd1yfa	240	23	)	)	-RRB-
cord-015935-r2wd1yfa	240	24	provides	provide	VBZ
cord-015935-r2wd1yfa	240	25	a	a	DT
cord-015935-r2wd1yfa	240	26	window	window	NN
cord-015935-r2wd1yfa	240	27	into	into	IN
cord-015935-r2wd1yfa	240	28	the	the	DT
cord-015935-r2wd1yfa	240	29	shared	share	VBN
cord-015935-r2wd1yfa	240	30	biology	biology	NN
cord-015935-r2wd1yfa	240	31	between	between	IN
cord-015935-r2wd1yfa	240	32	the	the	DT
cord-015935-r2wd1yfa	240	33	disorders	disorder	NNS
cord-015935-r2wd1yfa	240	34	.	.	.
cord-015935-r2wd1yfa	241	1	FMRP	FMRP	NNP
cord-015935-r2wd1yfa	241	2	has	have	VBZ
cord-015935-r2wd1yfa	241	3	been	be	VBN
cord-015935-r2wd1yfa	241	4	shown	show	VBN
cord-015935-r2wd1yfa	241	5	to	to	TO
cord-015935-r2wd1yfa	241	6	interact	interact	VB
cord-015935-r2wd1yfa	241	7	with	with	IN
cord-015935-r2wd1yfa	241	8	multiple	multiple	JJ
cord-015935-r2wd1yfa	241	9	transcripts	transcript	NNS
cord-015935-r2wd1yfa	241	10	in	in	IN
cord-015935-r2wd1yfa	241	11	repressing	repress	VBG
cord-015935-r2wd1yfa	241	12	metabotropic	metabotropic	NNP
cord-015935-r2wd1yfa	241	13	glutamate	glutamate	NN
cord-015935-r2wd1yfa	241	14	receptor-5	receptor-5	NNP
cord-015935-r2wd1yfa	241	15	(	(	-LRB-
cord-015935-r2wd1yfa	242	1	mGluR	mGluR	NNP
cord-015935-r2wd1yfa	242	2	5	5	LS
cord-015935-r2wd1yfa	242	3	)	)	-RRB-
cord-015935-r2wd1yfa	242	4	signaling	signal	VBG
cord-015935-r2wd1yfa	242	5	activity	activity	NN
cord-015935-r2wd1yfa	242	6	which	which	WDT
cord-015935-r2wd1yfa	242	7	regulates	regulate	VBZ
cord-015935-r2wd1yfa	242	8	long	long	JJ
cord-015935-r2wd1yfa	242	9	-	-	HYPH
cord-015935-r2wd1yfa	242	10	term	term	NN
cord-015935-r2wd1yfa	242	11	depression	depression	NN
cord-015935-r2wd1yfa	242	12	(	(	-LRB-
cord-015935-r2wd1yfa	242	13	LTD	LTD	NNP
cord-015935-r2wd1yfa	242	14	)	)	-RRB-
cord-015935-r2wd1yfa	242	15	associated	associate	VBN
cord-015935-r2wd1yfa	242	16	with	with	IN
cord-015935-r2wd1yfa	242	17	synaptic	synaptic	JJ
cord-015935-r2wd1yfa	242	18	elimination	elimination	NN
cord-015935-r2wd1yfa	242	19	.	.	.
cord-015935-r2wd1yfa	243	1	Without	without	IN
cord-015935-r2wd1yfa	243	2	FMRP	FMRP	NNP
cord-015935-r2wd1yfa	243	3	acting	act	VBG
cord-015935-r2wd1yfa	243	4	as	as	IN
cord-015935-r2wd1yfa	243	5	a	a	DT
cord-015935-r2wd1yfa	243	6	"	"	``
cord-015935-r2wd1yfa	243	7	brake	brake	NN
cord-015935-r2wd1yfa	243	8	,	,	,
cord-015935-r2wd1yfa	243	9	"	"	''
cord-015935-r2wd1yfa	243	10	mGluR	mGluR	NNP
cord-015935-r2wd1yfa	243	11	-	-	HYPH
cord-015935-r2wd1yfa	243	12	LTD	LTD	NNP
cord-015935-r2wd1yfa	243	13	is	be	VBZ
cord-015935-r2wd1yfa	243	14	enhanced	enhance	VBN
cord-015935-r2wd1yfa	243	15	(	(	-LRB-
cord-015935-r2wd1yfa	243	16	Bear	Bear	NNP
cord-015935-r2wd1yfa	243	17	,	,	,
cord-015935-r2wd1yfa	243	18	Huber	Huber	NNP
cord-015935-r2wd1yfa	243	19	,	,	,
cord-015935-r2wd1yfa	243	20	&	&	CC
cord-015935-r2wd1yfa	243	21	Warren	Warren	NNP
cord-015935-r2wd1yfa	243	22	,	,	,
cord-015935-r2wd1yfa	243	23	2004	2004	CD
cord-015935-r2wd1yfa	243	24	)	)	-RRB-
cord-015935-r2wd1yfa	243	25	.	.	.
cord-015935-r2wd1yfa	244	1	This	this	DT
cord-015935-r2wd1yfa	244	2	favors	favor	VBZ
cord-015935-r2wd1yfa	244	3	an	an	DT
cord-015935-r2wd1yfa	244	4	anabolic	anabolic	JJ
cord-015935-r2wd1yfa	244	5	state	state	NN
cord-015935-r2wd1yfa	244	6	which	which	WDT
cord-015935-r2wd1yfa	244	7	could	could	MD
cord-015935-r2wd1yfa	244	8	contribute	contribute	VB
cord-015935-r2wd1yfa	244	9	to	to	IN
cord-015935-r2wd1yfa	244	10	the	the	DT
cord-015935-r2wd1yfa	244	11	key	key	JJ
cord-015935-r2wd1yfa	244	12	features	feature	NNS
cord-015935-r2wd1yfa	244	13	of	of	IN
cord-015935-r2wd1yfa	244	14	FXS	FXS	NNP
cord-015935-r2wd1yfa	244	15	such	such	JJ
cord-015935-r2wd1yfa	244	16	as	as	IN
cord-015935-r2wd1yfa	244	17	epilepsy	epilepsy	NN
cord-015935-r2wd1yfa	244	18	,	,	,
cord-015935-r2wd1yfa	244	19	cognitive	cognitive	JJ
cord-015935-r2wd1yfa	244	20	impairment	impairment	NN
cord-015935-r2wd1yfa	244	21	,	,	,
cord-015935-r2wd1yfa	244	22	loss	loss	NN
cord-015935-r2wd1yfa	244	23	of	of	IN
cord-015935-r2wd1yfa	244	24	motor	motor	NN
cord-015935-r2wd1yfa	244	25	coordination	coordination	NN
cord-015935-r2wd1yfa	244	26	,	,	,
cord-015935-r2wd1yfa	244	27	and	and	CC
cord-015935-r2wd1yfa	244	28	increased	increase	VBN
cord-015935-r2wd1yfa	244	29	density	density	NN
cord-015935-r2wd1yfa	244	30	of	of	IN
cord-015935-r2wd1yfa	244	31	thin	thin	JJ
cord-015935-r2wd1yfa	244	32	,	,	,
cord-015935-r2wd1yfa	244	33	long	long	JJ
cord-015935-r2wd1yfa	244	34	,	,	,
cord-015935-r2wd1yfa	244	35	dendritic	dendritic	JJ
cord-015935-r2wd1yfa	244	36	spines	spine	NNS
cord-015935-r2wd1yfa	244	37	in	in	IN
cord-015935-r2wd1yfa	244	38	neurons	neuron	NNS
cord-015935-r2wd1yfa	244	39	(	(	-LRB-
cord-015935-r2wd1yfa	244	40	Bear	Bear	NNP
cord-015935-r2wd1yfa	244	41	,	,	,
cord-015935-r2wd1yfa	244	42	2005	2005	CD
cord-015935-r2wd1yfa	244	43	)	)	-RRB-
cord-015935-r2wd1yfa	244	44	.	.	.
cord-015935-r2wd1yfa	245	1	These	these	DT
cord-015935-r2wd1yfa	245	2	observations	observation	NNS
cord-015935-r2wd1yfa	245	3	have	have	VBP
cord-015935-r2wd1yfa	245	4	invited	invite	VBN
cord-015935-r2wd1yfa	245	5	drug	drug	NN
cord-015935-r2wd1yfa	245	6	trials	trial	NNS
cord-015935-r2wd1yfa	245	7	of	of	IN
cord-015935-r2wd1yfa	245	8	glutamate	glutamate	NN
cord-015935-r2wd1yfa	245	9	receptor	receptor	NN
cord-015935-r2wd1yfa	245	10	antagonists	antagonist	NNS
cord-015935-r2wd1yfa	245	11	to	to	TO
cord-015935-r2wd1yfa	245	12	reduce	reduce	VB
cord-015935-r2wd1yfa	245	13	the	the	DT
cord-015935-r2wd1yfa	245	14	expression	expression	NN
cord-015935-r2wd1yfa	245	15	of	of	IN
cord-015935-r2wd1yfa	245	16	mGluR	mglur	NN
cord-015935-r2wd1yfa	245	17	5	5	CD
cord-015935-r2wd1yfa	246	1	(	(	-LRB-
cord-015935-r2wd1yfa	246	2	Dolen	Dolen	NNP
cord-015935-r2wd1yfa	246	3	et	et	NNP
cord-015935-r2wd1yfa	246	4	al	al	NNP
cord-015935-r2wd1yfa	246	5	.	.	NNP
cord-015935-r2wd1yfa	246	6	,	,	,
cord-015935-r2wd1yfa	246	7	2007	2007	CD
cord-015935-r2wd1yfa	246	8	)	)	-RRB-
cord-015935-r2wd1yfa	246	9	in	in	IN
cord-015935-r2wd1yfa	246	10	individuals	individual	NNS
cord-015935-r2wd1yfa	246	11	with	with	IN
cord-015935-r2wd1yfa	246	12	FXS	FXS	NNP
cord-015935-r2wd1yfa	246	13	and	and	CC
cord-015935-r2wd1yfa	246	14	in	in	IN
cord-015935-r2wd1yfa	246	15	individuals	individual	NNS
cord-015935-r2wd1yfa	246	16	with	with	IN
cord-015935-r2wd1yfa	246	17	autism	autism	NN
cord-015935-r2wd1yfa	246	18	.	.	.
cord-015935-r2wd1yfa	247	1	Other	other	JJ
cord-015935-r2wd1yfa	247	2	genes	gene	NNS
cord-015935-r2wd1yfa	247	3	contributing	contribute	VBG
cord-015935-r2wd1yfa	247	4	to	to	IN
cord-015935-r2wd1yfa	247	5	medical	medical	JJ
cord-015935-r2wd1yfa	247	6	conditions	condition	NNS
cord-015935-r2wd1yfa	247	7	such	such	JJ
cord-015935-r2wd1yfa	247	8	as	as	IN
cord-015935-r2wd1yfa	247	9	Alzheimer	Alzheimer	NNP
cord-015935-r2wd1yfa	247	10	's	's	POS
cord-015935-r2wd1yfa	247	11	disease	disease	NN
cord-015935-r2wd1yfa	247	12	are	be	VBP
cord-015935-r2wd1yfa	247	13	under	under	IN
cord-015935-r2wd1yfa	247	14	investigation	investigation	NN
cord-015935-r2wd1yfa	247	15	to	to	TO
cord-015935-r2wd1yfa	247	16	determine	determine	VB
cord-015935-r2wd1yfa	247	17	if	if	IN
cord-015935-r2wd1yfa	247	18	they	-PRON-	PRP
cord-015935-r2wd1yfa	247	19	,	,	,
cord-015935-r2wd1yfa	247	20	too	too	RB
cord-015935-r2wd1yfa	247	21	,	,	,
cord-015935-r2wd1yfa	247	22	share	share	VB
cord-015935-r2wd1yfa	247	23	biology	biology	NN
cord-015935-r2wd1yfa	247	24	with	with	IN
cord-015935-r2wd1yfa	247	25	autism	autism	NN
cord-015935-r2wd1yfa	247	26	and	and	CC
cord-015935-r2wd1yfa	247	27	FXS	FXS	NNP
cord-015935-r2wd1yfa	247	28	.	.	.
cord-015935-r2wd1yfa	248	1	The	the	DT
cord-015935-r2wd1yfa	248	2	discovery	discovery	NN
cord-015935-r2wd1yfa	248	3	of	of	IN
cord-015935-r2wd1yfa	248	4	fragile	fragile	JJ
cord-015935-r2wd1yfa	248	5	X	x	NN
cord-015935-r2wd1yfa	248	6	ataxia	ataxia	NN
cord-015935-r2wd1yfa	248	7	syndrome	syndrome	NN
cord-015935-r2wd1yfa	248	8	(	(	-LRB-
cord-015935-r2wd1yfa	248	9	FXTAS	FXTAS	NNP
cord-015935-r2wd1yfa	248	10	)	)	-RRB-
cord-015935-r2wd1yfa	248	11	provides	provide	VBZ
cord-015935-r2wd1yfa	248	12	a	a	DT
cord-015935-r2wd1yfa	248	13	precedent	precedent	NN
cord-015935-r2wd1yfa	248	14	to	to	TO
cord-015935-r2wd1yfa	248	15	study	study	VB
cord-015935-r2wd1yfa	248	16	the	the	DT
cord-015935-r2wd1yfa	248	17	relationship	relationship	NN
cord-015935-r2wd1yfa	248	18	of	of	IN
cord-015935-r2wd1yfa	248	19	developmental	developmental	JJ
cord-015935-r2wd1yfa	248	20	conditions	condition	NNS
cord-015935-r2wd1yfa	248	21	across	across	IN
cord-015935-r2wd1yfa	248	22	the	the	DT
cord-015935-r2wd1yfa	248	23	life	life	NN
cord-015935-r2wd1yfa	248	24	span	span	VB
cord-015935-r2wd1yfa	248	25	within	within	IN
cord-015935-r2wd1yfa	248	26	and	and	CC
cord-015935-r2wd1yfa	248	27	between	between	IN
cord-015935-r2wd1yfa	248	28	families	family	NNS
cord-015935-r2wd1yfa	248	29	.	.	.
cord-015935-r2wd1yfa	249	1	FXTAS	FXTAS	NNP
cord-015935-r2wd1yfa	249	2	is	be	VBZ
cord-015935-r2wd1yfa	249	3	an	an	DT
cord-015935-r2wd1yfa	249	4	adult	adult	NN
cord-015935-r2wd1yfa	249	5	-	-	HYPH
cord-015935-r2wd1yfa	249	6	onset	onset	NN
cord-015935-r2wd1yfa	249	7	ataxia	ataxia	NN
cord-015935-r2wd1yfa	249	8	/	/	SYM
cord-015935-r2wd1yfa	249	9	dementia	dementia	NN
cord-015935-r2wd1yfa	249	10	syndrome	syndrome	NN
cord-015935-r2wd1yfa	249	11	found	find	VBD
cord-015935-r2wd1yfa	249	12	in	in	IN
cord-015935-r2wd1yfa	249	13	older	old	JJR
cord-015935-r2wd1yfa	249	14	family	family	NN
cord-015935-r2wd1yfa	249	15	members	member	NNS
cord-015935-r2wd1yfa	249	16	of	of	IN
cord-015935-r2wd1yfa	249	17	individuals	individual	NNS
cord-015935-r2wd1yfa	249	18	with	with	IN
cord-015935-r2wd1yfa	249	19	FXS	FXS	NNP
cord-015935-r2wd1yfa	249	20	(	(	-LRB-
cord-015935-r2wd1yfa	249	21	Hagerman	Hagerman	NNP
cord-015935-r2wd1yfa	249	22	,	,	,
cord-015935-r2wd1yfa	249	23	2002	2002	CD
cord-015935-r2wd1yfa	249	24	;	;	:
cord-015935-r2wd1yfa	250	1	Hagerman	Hagerman	NNP
cord-015935-r2wd1yfa	250	2	et	et	NNP
cord-015935-r2wd1yfa	250	3	al	al	NNP
cord-015935-r2wd1yfa	250	4	.	.	NNP
cord-015935-r2wd1yfa	250	5	,	,	,
cord-015935-r2wd1yfa	250	6	2001	2001	CD
cord-015935-r2wd1yfa	250	7	)	)	-RRB-
cord-015935-r2wd1yfa	250	8	.	.	.
cord-015935-r2wd1yfa	251	1	In	in	IN
cord-015935-r2wd1yfa	251	2	contrast	contrast	NN
cord-015935-r2wd1yfa	251	3	to	to	IN
cord-015935-r2wd1yfa	251	4	what	what	WP
cord-015935-r2wd1yfa	251	5	is	be	VBZ
cord-015935-r2wd1yfa	251	6	found	find	VBN
cord-015935-r2wd1yfa	251	7	in	in	IN
cord-015935-r2wd1yfa	251	8	FXS	FXS	NNP
cord-015935-r2wd1yfa	251	9	,	,	,
cord-015935-r2wd1yfa	251	10	FXTAS	FXTAS	NNP
cord-015935-r2wd1yfa	251	11	occurs	occur	VBZ
cord-015935-r2wd1yfa	251	12	with	with	IN
cord-015935-r2wd1yfa	251	13	a	a	DT
cord-015935-r2wd1yfa	251	14	rise	rise	NN
cord-015935-r2wd1yfa	251	15	in	in	IN
cord-015935-r2wd1yfa	252	1	FMR1	FMR1	NNP
cord-015935-r2wd1yfa	252	2	mRNA	mrna	NN
cord-015935-r2wd1yfa	252	3	level	level	NN
cord-015935-r2wd1yfa	252	4	(	(	-LRB-
cord-015935-r2wd1yfa	252	5	Hagerman	Hagerman	NNP
cord-015935-r2wd1yfa	252	6	,	,	,
cord-015935-r2wd1yfa	252	7	2006	2006	CD
cord-015935-r2wd1yfa	252	8	)	)	-RRB-
cord-015935-r2wd1yfa	252	9	,	,	,
cord-015935-r2wd1yfa	252	10	fewer	few	JJR
cord-015935-r2wd1yfa	252	11	than	than	IN
cord-015935-r2wd1yfa	252	12	200	200	CD
cord-015935-r2wd1yfa	252	13	repeats	repeat	NNS
cord-015935-r2wd1yfa	252	14	(	(	-LRB-
cord-015935-r2wd1yfa	252	15	Basehore	Basehore	NNP
cord-015935-r2wd1yfa	252	16	&	&	CC
cord-015935-r2wd1yfa	252	17	Friez	Friez	NNP
cord-015935-r2wd1yfa	252	18	,	,	,
cord-015935-r2wd1yfa	252	19	2009	2009	CD
cord-015935-r2wd1yfa	252	20	)	)	-RRB-
cord-015935-r2wd1yfa	252	21	,	,	,
cord-015935-r2wd1yfa	252	22	and	and	CC
cord-015935-r2wd1yfa	252	23	hypomethylation	hypomethylation	NN
cord-015935-r2wd1yfa	252	24	(	(	-LRB-
cord-015935-r2wd1yfa	252	25	Berry	Berry	NNP
cord-015935-r2wd1yfa	252	26	-	-	HYPH
cord-015935-r2wd1yfa	252	27	Kravis	Kravis	NNP
cord-015935-r2wd1yfa	252	28	,	,	,
cord-015935-r2wd1yfa	252	29	Potanas	Potanas	NNP
cord-015935-r2wd1yfa	252	30	,	,	,
cord-015935-r2wd1yfa	252	31	Weinberg	Weinberg	NNP
cord-015935-r2wd1yfa	252	32	,	,	,
cord-015935-r2wd1yfa	252	33	Zhou	Zhou	NNP
cord-015935-r2wd1yfa	252	34	,	,	,
cord-015935-r2wd1yfa	252	35	&	&	CC
cord-015935-r2wd1yfa	252	36	Goetz	Goetz	NNP
cord-015935-r2wd1yfa	252	37	,	,	,
cord-015935-r2wd1yfa	252	38	2005	2005	CD
cord-015935-r2wd1yfa	252	39	)	)	-RRB-
cord-015935-r2wd1yfa	252	40	in	in	IN
cord-015935-r2wd1yfa	252	41	the	the	DT
cord-015935-r2wd1yfa	252	42	FMR1	FMR1	NNP
cord-015935-r2wd1yfa	252	43	CGG	CGG	NNP
cord-015935-r2wd1yfa	252	44	section	section	NN
cord-015935-r2wd1yfa	252	45	on	on	IN
cord-015935-r2wd1yfa	252	46	the	the	DT
cord-015935-r2wd1yfa	252	47	X	x	NN
cord-015935-r2wd1yfa	252	48	chromosome	chromosome	NN
cord-015935-r2wd1yfa	252	49	.	.	.
cord-015935-r2wd1yfa	253	1	This	this	DT
cord-015935-r2wd1yfa	253	2	association	association	NN
cord-015935-r2wd1yfa	253	3	of	of	IN
cord-015935-r2wd1yfa	253	4	two	two	CD
cord-015935-r2wd1yfa	253	5	clinically	clinically	RB
cord-015935-r2wd1yfa	253	6	divergent	divergent	JJ
cord-015935-r2wd1yfa	253	7	disorders	disorder	NNS
cord-015935-r2wd1yfa	253	8	,	,	,
cord-015935-r2wd1yfa	253	9	regulated	regulate	VBN
cord-015935-r2wd1yfa	253	10	by	by	IN
cord-015935-r2wd1yfa	253	11	the	the	DT
cord-015935-r2wd1yfa	253	12	same	same	JJ
cord-015935-r2wd1yfa	253	13	gene	gene	NN
cord-015935-r2wd1yfa	253	14	produced	produce	VBN
cord-015935-r2wd1yfa	253	15	in	in	IN
cord-015935-r2wd1yfa	253	16	different	different	JJ
cord-015935-r2wd1yfa	253	17	doses	dose	NNS
cord-015935-r2wd1yfa	253	18	,	,	,
cord-015935-r2wd1yfa	253	19	sets	set	VBZ
cord-015935-r2wd1yfa	253	20	the	the	DT
cord-015935-r2wd1yfa	253	21	stage	stage	NN
cord-015935-r2wd1yfa	253	22	for	for	IN
cord-015935-r2wd1yfa	253	23	the	the	DT
cord-015935-r2wd1yfa	253	24	investigation	investigation	NN
cord-015935-r2wd1yfa	253	25	of	of	IN
cord-015935-r2wd1yfa	253	26	the	the	DT
cord-015935-r2wd1yfa	253	27	shared	share	VBN
cord-015935-r2wd1yfa	253	28	biology	biology	NN
cord-015935-r2wd1yfa	253	29	between	between	IN
cord-015935-r2wd1yfa	253	30	autism	autism	NN
cord-015935-r2wd1yfa	253	31	,	,	,
cord-015935-r2wd1yfa	253	32	FXS	FXS	NNP
cord-015935-r2wd1yfa	253	33	,	,	,
cord-015935-r2wd1yfa	253	34	and	and	CC
cord-015935-r2wd1yfa	253	35	other	other	JJ
cord-015935-r2wd1yfa	253	36	genes	gene	NNS
cord-015935-r2wd1yfa	253	37	related	relate	VBN
cord-015935-r2wd1yfa	253	38	to	to	IN
cord-015935-r2wd1yfa	253	39	Alzheimer	Alzheimer	NNP
cord-015935-r2wd1yfa	253	40	's	's	POS
cord-015935-r2wd1yfa	253	41	disease	disease	NN
cord-015935-r2wd1yfa	253	42	such	such	JJ
cord-015935-r2wd1yfa	253	43	as	as	IN
cord-015935-r2wd1yfa	253	44	amyloid	amyloid	NN
cord-015935-r2wd1yfa	253	45	precursor	precursor	NN
cord-015935-r2wd1yfa	253	46	protein	protein	NN
cord-015935-r2wd1yfa	253	47	(	(	-LRB-
cord-015935-r2wd1yfa	253	48	APP	app	NN
cord-015935-r2wd1yfa	253	49	)	)	-RRB-
cord-015935-r2wd1yfa	253	50	.	.	.
cord-015935-r2wd1yfa	254	1	APP	APP	NNP
cord-015935-r2wd1yfa	254	2	,	,	,
cord-015935-r2wd1yfa	254	3	which	which	WDT
cord-015935-r2wd1yfa	254	4	is	be	VBZ
cord-015935-r2wd1yfa	254	5	encoded	encode	VBN
cord-015935-r2wd1yfa	254	6	by	by	IN
cord-015935-r2wd1yfa	254	7	a	a	DT
cord-015935-r2wd1yfa	254	8	gene	gene	NN
cord-015935-r2wd1yfa	254	9	on	on	IN
cord-015935-r2wd1yfa	254	10	chromosome	chromosome	NN
cord-015935-r2wd1yfa	254	11	21	21	CD
cord-015935-r2wd1yfa	254	12	,	,	,
cord-015935-r2wd1yfa	254	13	is	be	VBZ
cord-015935-r2wd1yfa	254	14	a	a	DT
cord-015935-r2wd1yfa	254	15	large	large	JJ
cord-015935-r2wd1yfa	254	16	(	(	-LRB-
cord-015935-r2wd1yfa	254	17	695	695	CD
cord-015935-r2wd1yfa	254	18	-	-	SYM
cord-015935-r2wd1yfa	254	19	770	770	CD
cord-015935-r2wd1yfa	254	20	amino	amino	NN
cord-015935-r2wd1yfa	254	21	acid	acid	NN
cord-015935-r2wd1yfa	254	22	)	)	-RRB-
cord-015935-r2wd1yfa	254	23	glycoprotein	glycoprotein	NN
cord-015935-r2wd1yfa	254	24	produced	produce	VBN
cord-015935-r2wd1yfa	254	25	in	in	IN
cord-015935-r2wd1yfa	254	26	several	several	JJ
cord-015935-r2wd1yfa	254	27	central	central	JJ
cord-015935-r2wd1yfa	254	28	nervous	nervous	JJ
cord-015935-r2wd1yfa	254	29	system	system	NN
cord-015935-r2wd1yfa	254	30	(	(	-LRB-
cord-015935-r2wd1yfa	254	31	CNS	CNS	NNP
cord-015935-r2wd1yfa	254	32	)	)	-RRB-
cord-015935-r2wd1yfa	254	33	cell	cell	NN
cord-015935-r2wd1yfa	254	34	types	type	NNS
cord-015935-r2wd1yfa	254	35	including	include	VBG
cord-015935-r2wd1yfa	254	36	microglia	microglia	NNS
cord-015935-r2wd1yfa	254	37	,	,	,
cord-015935-r2wd1yfa	254	38	astrocytes	astrocyte	NNS
cord-015935-r2wd1yfa	254	39	,	,	,
cord-015935-r2wd1yfa	254	40	oligodendrocytes	oligodendrocyte	NNS
cord-015935-r2wd1yfa	254	41	,	,	,
cord-015935-r2wd1yfa	254	42	and	and	CC
cord-015935-r2wd1yfa	254	43	neurons	neuron	NNS
cord-015935-r2wd1yfa	254	44	.	.	.
cord-015935-r2wd1yfa	255	1	After	after	IN
cord-015935-r2wd1yfa	255	2	protein	protein	NN
cord-015935-r2wd1yfa	255	3	processing	processing	NN
cord-015935-r2wd1yfa	255	4	,	,	,
cord-015935-r2wd1yfa	255	5	mature	mature	JJ
cord-015935-r2wd1yfa	255	6	APP	app	NN
cord-015935-r2wd1yfa	255	7	is	be	VBZ
cord-015935-r2wd1yfa	255	8	axonally	axonally	RB
cord-015935-r2wd1yfa	255	9	transported	transport	VBN
cord-015935-r2wd1yfa	255	10	and	and	CC
cord-015935-r2wd1yfa	255	11	can	can	MD
cord-015935-r2wd1yfa	255	12	be	be	VB
cord-015935-r2wd1yfa	255	13	released	release	VBN
cord-015935-r2wd1yfa	255	14	from	from	IN
cord-015935-r2wd1yfa	255	15	axon	axon	NN
cord-015935-r2wd1yfa	255	16	terminals	terminal	NNS
cord-015935-r2wd1yfa	255	17	in	in	IN
cord-015935-r2wd1yfa	255	18	response	response	NN
cord-015935-r2wd1yfa	255	19	to	to	IN
cord-015935-r2wd1yfa	255	20	electrical	electrical	JJ
cord-015935-r2wd1yfa	255	21	activity	activity	NN
cord-015935-r2wd1yfa	255	22	.	.	.
cord-015935-r2wd1yfa	256	1	APP	APP	NNP
cord-015935-r2wd1yfa	256	2	is	be	VBZ
cord-015935-r2wd1yfa	256	3	believed	believe	VBN
cord-015935-r2wd1yfa	256	4	to	to	TO
cord-015935-r2wd1yfa	256	5	play	play	VB
cord-015935-r2wd1yfa	256	6	an	an	DT
cord-015935-r2wd1yfa	256	7	important	important	JJ
cord-015935-r2wd1yfa	256	8	role	role	NN
cord-015935-r2wd1yfa	256	9	in	in	IN
cord-015935-r2wd1yfa	256	10	neuronal	neuronal	JJ
cord-015935-r2wd1yfa	256	11	maturation	maturation	NN
cord-015935-r2wd1yfa	256	12	and	and	CC
cord-015935-r2wd1yfa	256	13	in	in	IN
cord-015935-r2wd1yfa	256	14	synaptogenesis	synaptogenesis	NN
cord-015935-r2wd1yfa	256	15	as	as	IN
cord-015935-r2wd1yfa	256	16	reviewed	review	VBN
cord-015935-r2wd1yfa	256	17	by	by	IN
cord-015935-r2wd1yfa	256	18	Lahiri	Lahiri	NNP
cord-015935-r2wd1yfa	256	19	,	,	,
cord-015935-r2wd1yfa	256	20	Farlow	Farlow	NNP
cord-015935-r2wd1yfa	256	21	,	,	,
cord-015935-r2wd1yfa	256	22	Greig	Greig	NNP
cord-015935-r2wd1yfa	256	23	,	,	,
cord-015935-r2wd1yfa	256	24	Giacobini	Giacobini	NNP
cord-015935-r2wd1yfa	256	25	,	,	,
cord-015935-r2wd1yfa	256	26	and	and	CC
cord-015935-r2wd1yfa	256	27	Schneider	Schneider	NNP
cord-015935-r2wd1yfa	256	28	(	(	-LRB-
cord-015935-r2wd1yfa	256	29	2003	2003	CD
cord-015935-r2wd1yfa	256	30	)	)	-RRB-
cord-015935-r2wd1yfa	256	31	.	.	.
cord-015935-r2wd1yfa	257	1	APP	app	NN
cord-015935-r2wd1yfa	257	2	is	be	VBZ
cord-015935-r2wd1yfa	257	3	of	of	IN
cord-015935-r2wd1yfa	257	4	great	great	JJ
cord-015935-r2wd1yfa	257	5	interest	interest	NN
cord-015935-r2wd1yfa	257	6	because	because	IN
cord-015935-r2wd1yfa	257	7	processing	process	VBG
cord-015935-r2wd1yfa	257	8	products	product	NNS
cord-015935-r2wd1yfa	257	9	of	of	IN
cord-015935-r2wd1yfa	257	10	APP	app	NN
cord-015935-r2wd1yfa	257	11	can	can	MD
cord-015935-r2wd1yfa	257	12	include	include	VB
cord-015935-r2wd1yfa	257	13	the	the	DT
cord-015935-r2wd1yfa	257	14	insoluble	insoluble	JJ
cord-015935-r2wd1yfa	257	15	40	40	CD
cord-015935-r2wd1yfa	257	16	-	-	SYM
cord-015935-r2wd1yfa	257	17	42-amino	42-amino	CD
cord-015935-r2wd1yfa	257	18	acid	acid	NN
cord-015935-r2wd1yfa	257	19	amyloid	amyloid	NN
cord-015935-r2wd1yfa	257	20	β	β	NN
cord-015935-r2wd1yfa	257	21	-	-	HYPH
cord-015935-r2wd1yfa	257	22	peptide	peptide	NN
cord-015935-r2wd1yfa	257	23	(	(	-LRB-
cord-015935-r2wd1yfa	257	24	Aβ-40	Aβ-40	NNP
cord-015935-r2wd1yfa	257	25	and	and	CC
cord-015935-r2wd1yfa	257	26	Aβ-42	Aβ-42	NNP
cord-015935-r2wd1yfa	257	27	,	,	,
cord-015935-r2wd1yfa	257	28	respectively	respectively	RB
cord-015935-r2wd1yfa	257	29	)	)	-RRB-
cord-015935-r2wd1yfa	257	30	,	,	,
cord-015935-r2wd1yfa	257	31	the	the	DT
cord-015935-r2wd1yfa	257	32	principal	principal	JJ
cord-015935-r2wd1yfa	257	33	component	component	NN
cord-015935-r2wd1yfa	257	34	of	of	IN
cord-015935-r2wd1yfa	257	35	the	the	DT
cord-015935-r2wd1yfa	257	36	cerebral	cerebral	JJ
cord-015935-r2wd1yfa	257	37	plaques	plaque	NNS
cord-015935-r2wd1yfa	257	38	associated	associate	VBN
cord-015935-r2wd1yfa	257	39	with	with	IN
cord-015935-r2wd1yfa	257	40	memory	memory	NN
cord-015935-r2wd1yfa	257	41	and	and	CC
cord-015935-r2wd1yfa	257	42	cognitive	cognitive	JJ
cord-015935-r2wd1yfa	257	43	decline	decline	NN
cord-015935-r2wd1yfa	257	44	in	in	IN
cord-015935-r2wd1yfa	257	45	Alzheimer	Alzheimer	NNP
cord-015935-r2wd1yfa	257	46	's	's	POS
cord-015935-r2wd1yfa	257	47	disease	disease	NN
cord-015935-r2wd1yfa	257	48	(	(	-LRB-
cord-015935-r2wd1yfa	257	49	Alley	Alley	NNP
cord-015935-r2wd1yfa	257	50	et	et	FW
cord-015935-r2wd1yfa	257	51	al	al	NNP
cord-015935-r2wd1yfa	257	52	.	.	NNP
cord-015935-r2wd1yfa	257	53	,	,	,
cord-015935-r2wd1yfa	257	54	2010	2010	CD
cord-015935-r2wd1yfa	257	55	)	)	-RRB-
cord-015935-r2wd1yfa	257	56	.	.	.
cord-015935-r2wd1yfa	258	1	Recent	recent	JJ
cord-015935-r2wd1yfa	258	2	research	research	NN
cord-015935-r2wd1yfa	258	3	linking	link	VBG
cord-015935-r2wd1yfa	258	4	APP	app	NN
cord-015935-r2wd1yfa	258	5	to	to	IN
cord-015935-r2wd1yfa	258	6	autism	autism	NN
cord-015935-r2wd1yfa	258	7	illustrates	illustrate	VBZ
cord-015935-r2wd1yfa	258	8	how	how	WRB
cord-015935-r2wd1yfa	258	9	association	association	NN
cord-015935-r2wd1yfa	258	10	studies	study	NNS
cord-015935-r2wd1yfa	258	11	enable	enable	VBP
cord-015935-r2wd1yfa	258	12	the	the	DT
cord-015935-r2wd1yfa	258	13	generation	generation	NN
cord-015935-r2wd1yfa	258	14	of	of	IN
cord-015935-r2wd1yfa	258	15	new	new	JJ
cord-015935-r2wd1yfa	258	16	hypotheses	hypothesis	NNS
cord-015935-r2wd1yfa	258	17	about	about	IN
cord-015935-r2wd1yfa	258	18	the	the	DT
cord-015935-r2wd1yfa	258	19	biology	biology	NN
cord-015935-r2wd1yfa	258	20	of	of	IN
cord-015935-r2wd1yfa	258	21	autism	autism	NN
cord-015935-r2wd1yfa	258	22	and	and	CC
cord-015935-r2wd1yfa	258	23	ultimately	ultimately	RB
cord-015935-r2wd1yfa	258	24	advance	advance	VB
cord-015935-r2wd1yfa	258	25	our	-PRON-	PRP$
cord-015935-r2wd1yfa	258	26	understanding	understanding	NN
cord-015935-r2wd1yfa	258	27	of	of	IN
cord-015935-r2wd1yfa	258	28	this	this	DT
cord-015935-r2wd1yfa	258	29	disorder	disorder	NN
cord-015935-r2wd1yfa	258	30	.	.	.
cord-015935-r2wd1yfa	259	1	Recently	recently	RB
cord-015935-r2wd1yfa	259	2	,	,	,
cord-015935-r2wd1yfa	259	3	we	-PRON-	PRP
cord-015935-r2wd1yfa	259	4	found	find	VBD
cord-015935-r2wd1yfa	259	5	evidence	evidence	NN
cord-015935-r2wd1yfa	259	6	to	to	TO
cord-015935-r2wd1yfa	259	7	support	support	VB
cord-015935-r2wd1yfa	259	8	an	an	DT
cord-015935-r2wd1yfa	259	9	association	association	NN
cord-015935-r2wd1yfa	259	10	between	between	IN
cord-015935-r2wd1yfa	259	11	autism	autism	NN
cord-015935-r2wd1yfa	259	12	and	and	CC
cord-015935-r2wd1yfa	259	13	one	one	CD
cord-015935-r2wd1yfa	259	14	of	of	IN
cord-015935-r2wd1yfa	259	15	the	the	DT
cord-015935-r2wd1yfa	259	16	APP	app	NN
cord-015935-r2wd1yfa	259	17	pathways	pathway	NNS
cord-015935-r2wd1yfa	259	18	established	establish	VBN
cord-015935-r2wd1yfa	259	19	for	for	IN
cord-015935-r2wd1yfa	259	20	Alzheimer	Alzheimer	NNP
cord-015935-r2wd1yfa	259	21	's	's	POS
cord-015935-r2wd1yfa	259	22	disease	disease	NN
cord-015935-r2wd1yfa	259	23	.	.	.
cord-015935-r2wd1yfa	260	1	In	in	IN
cord-015935-r2wd1yfa	260	2	contrast	contrast	NN
cord-015935-r2wd1yfa	260	3	to	to	IN
cord-015935-r2wd1yfa	260	4	the	the	DT
cord-015935-r2wd1yfa	260	5	upregulation	upregulation	NN
cord-015935-r2wd1yfa	260	6	of	of	IN
cord-015935-r2wd1yfa	260	7	the	the	DT
cord-015935-r2wd1yfa	260	8	amyloidogenic	amyloidogenic	NNP
cord-015935-r2wd1yfa	260	9	pathway	pathway	NN
cord-015935-r2wd1yfa	260	10	as	as	IN
cord-015935-r2wd1yfa	260	11	seen	see	VBN
cord-015935-r2wd1yfa	260	12	in	in	IN
cord-015935-r2wd1yfa	260	13	Alzheimer	Alzheimer	NNP
cord-015935-r2wd1yfa	260	14	's	's	POS
cord-015935-r2wd1yfa	260	15	disease	disease	NN
cord-015935-r2wd1yfa	260	16	,	,	,
cord-015935-r2wd1yfa	260	17	we	-PRON-	PRP
cord-015935-r2wd1yfa	260	18	found	find	VBD
cord-015935-r2wd1yfa	260	19	evidence	evidence	NN
cord-015935-r2wd1yfa	260	20	that	that	IN
cord-015935-r2wd1yfa	260	21	there	there	EX
cord-015935-r2wd1yfa	260	22	may	may	MD
cord-015935-r2wd1yfa	260	23	be	be	VB
cord-015935-r2wd1yfa	260	24	an	an	DT
cord-015935-r2wd1yfa	260	25	upregulation	upregulation	NN
cord-015935-r2wd1yfa	260	26	of	of	IN
cord-015935-r2wd1yfa	260	27	the	the	DT
cord-015935-r2wd1yfa	260	28	nonamyloidogenic	nonamyloidogenic	NNP
cord-015935-r2wd1yfa	260	29	(	(	-LRB-
cord-015935-r2wd1yfa	260	30	α	α	NNP
cord-015935-r2wd1yfa	260	31	-	-	HYPH
cord-015935-r2wd1yfa	260	32	secretase	secretase	NNP
cord-015935-r2wd1yfa	260	33	amyloid	amyloid	NN
cord-015935-r2wd1yfa	260	34	precursor	precursor	NN
cord-015935-r2wd1yfa	260	35	protein	protein	NN
cord-015935-r2wd1yfa	260	36	,	,	,
cord-015935-r2wd1yfa	260	37	sAPPα	sAPPα	NFP
cord-015935-r2wd1yfa	260	38	)	)	-RRB-
cord-015935-r2wd1yfa	260	39	pathway	pathway	NN
cord-015935-r2wd1yfa	260	40	in	in	IN
cord-015935-r2wd1yfa	260	41	a	a	DT
cord-015935-r2wd1yfa	260	42	small	small	JJ
cord-015935-r2wd1yfa	260	43	sample	sample	NN
cord-015935-r2wd1yfa	260	44	of	of	IN
cord-015935-r2wd1yfa	260	45	children	child	NNS
cord-015935-r2wd1yfa	260	46	with	with	IN
cord-015935-r2wd1yfa	260	47	severe	severe	JJ
cord-015935-r2wd1yfa	260	48	autism	autism	NN
cord-015935-r2wd1yfa	260	49	associated	associate	VBN
cord-015935-r2wd1yfa	260	50	with	with	IN
cord-015935-r2wd1yfa	260	51	self	self	NN
cord-015935-r2wd1yfa	260	52	-	-	HYPH
cord-015935-r2wd1yfa	260	53	injurious	injurious	JJ
cord-015935-r2wd1yfa	260	54	and	and	CC
cord-015935-r2wd1yfa	260	55	aggressive	aggressive	JJ
cord-015935-r2wd1yfa	260	56	behavior	behavior	NN
cord-015935-r2wd1yfa	260	57	.	.	.
cord-015935-r2wd1yfa	261	1	That	that	RB
cord-015935-r2wd1yfa	261	2	is	is	RB
cord-015935-r2wd1yfa	261	3	,	,	,
cord-015935-r2wd1yfa	261	4	children	child	NNS
cord-015935-r2wd1yfa	261	5	with	with	IN
cord-015935-r2wd1yfa	261	6	severe	severe	JJ
cord-015935-r2wd1yfa	261	7	autism	autism	NN
cord-015935-r2wd1yfa	261	8	expressed	express	VBD
cord-015935-r2wd1yfa	261	9	total	total	NN
cord-015935-r2wd1yfa	261	10	sAPP	sapp	JJ
cord-015935-r2wd1yfa	261	11	(	(	-LRB-
cord-015935-r2wd1yfa	261	12	representing	represent	VBG
cord-015935-r2wd1yfa	261	13	the	the	DT
cord-015935-r2wd1yfa	261	14	combined	combine	VBN
cord-015935-r2wd1yfa	261	15	amyloidogenic	amyloidogenic	NNP
cord-015935-r2wd1yfa	261	16	and	and	CC
cord-015935-r2wd1yfa	261	17	nonamyloidogenic	nonamyloidogenic	JJ
cord-015935-r2wd1yfa	261	18	pathways	pathway	NNS
cord-015935-r2wd1yfa	261	19	)	)	-RRB-
cord-015935-r2wd1yfa	261	20	at	at	IN
cord-015935-r2wd1yfa	261	21	two	two	CD
cord-015935-r2wd1yfa	261	22	or	or	CC
cord-015935-r2wd1yfa	261	23	more	more	JJR
cord-015935-r2wd1yfa	261	24	times	time	NNS
cord-015935-r2wd1yfa	261	25	the	the	DT
cord-015935-r2wd1yfa	261	26	levels	level	NNS
cord-015935-r2wd1yfa	261	27	of	of	IN
cord-015935-r2wd1yfa	261	28	children	child	NNS
cord-015935-r2wd1yfa	261	29	without	without	IN
cord-015935-r2wd1yfa	261	30	autism	autism	NN
cord-015935-r2wd1yfa	261	31	and	and	CC
cord-015935-r2wd1yfa	261	32	up	up	IN
cord-015935-r2wd1yfa	261	33	to	to	TO
cord-015935-r2wd1yfa	261	34	four	four	CD
cord-015935-r2wd1yfa	261	35	times	time	NNS
cord-015935-r2wd1yfa	261	36	the	the	DT
cord-015935-r2wd1yfa	261	37	levels	level	NNS
cord-015935-r2wd1yfa	261	38	of	of	IN
cord-015935-r2wd1yfa	261	39	children	child	NNS
cord-015935-r2wd1yfa	261	40	with	with	IN
cord-015935-r2wd1yfa	261	41	mild	mild	JJ
cord-015935-r2wd1yfa	261	42	autism	autism	NN
cord-015935-r2wd1yfa	261	43	(	(	-LRB-
cord-015935-r2wd1yfa	261	44	Sokol	Sokol	NNP
cord-015935-r2wd1yfa	261	45	et	et	NNP
cord-015935-r2wd1yfa	261	46	al	al	NNP
cord-015935-r2wd1yfa	261	47	.	.	NNP
cord-015935-r2wd1yfa	261	48	,	,	,
cord-015935-r2wd1yfa	261	49	2006	2006	CD
cord-015935-r2wd1yfa	261	50	)	)	-RRB-
cord-015935-r2wd1yfa	261	51	.	.	.
cord-015935-r2wd1yfa	262	1	Overall	overall	RB
cord-015935-r2wd1yfa	262	2	,	,	,
cord-015935-r2wd1yfa	262	3	there	there	EX
cord-015935-r2wd1yfa	262	4	was	be	VBD
cord-015935-r2wd1yfa	262	5	a	a	DT
cord-015935-r2wd1yfa	262	6	trend	trend	NN
cord-015935-r2wd1yfa	262	7	toward	toward	IN
cord-015935-r2wd1yfa	262	8	higher	high	JJR
cord-015935-r2wd1yfa	262	9	sAPPα	sAPPα	NNS
cord-015935-r2wd1yfa	262	10	within	within	IN
cord-015935-r2wd1yfa	262	11	the	the	DT
cord-015935-r2wd1yfa	262	12	children	child	NNS
cord-015935-r2wd1yfa	262	13	with	with	IN
cord-015935-r2wd1yfa	262	14	autism	autism	NN
cord-015935-r2wd1yfa	262	15	.	.	.
cord-015935-r2wd1yfa	263	1	One	one	CD
cord-015935-r2wd1yfa	263	2	of	of	IN
cord-015935-r2wd1yfa	263	3	the	the	DT
cord-015935-r2wd1yfa	263	4	severely	severely	RB
cord-015935-r2wd1yfa	263	5	autistic	autistic	JJ
cord-015935-r2wd1yfa	263	6	children	child	NNS
cord-015935-r2wd1yfa	263	7	in	in	IN
cord-015935-r2wd1yfa	263	8	this	this	DT
cord-015935-r2wd1yfa	263	9	study	study	NN
cord-015935-r2wd1yfa	263	10	had	have	VBD
cord-015935-r2wd1yfa	263	11	FXS	FXS	NNP
cord-015935-r2wd1yfa	263	12	.	.	.
cord-015935-r2wd1yfa	264	1	High	high	JJ
cord-015935-r2wd1yfa	264	2	levels	level	NNS
cord-015935-r2wd1yfa	264	3	of	of	IN
cord-015935-r2wd1yfa	264	4	sAPPα	sAPPα	NNS
cord-015935-r2wd1yfa	264	5	have	have	VBP
cord-015935-r2wd1yfa	264	6	also	also	RB
cord-015935-r2wd1yfa	264	7	been	be	VBN
cord-015935-r2wd1yfa	264	8	found	find	VBN
cord-015935-r2wd1yfa	264	9	in	in	IN
cord-015935-r2wd1yfa	264	10	a	a	DT
cord-015935-r2wd1yfa	264	11	sample	sample	NN
cord-015935-r2wd1yfa	264	12	of	of	IN
cord-015935-r2wd1yfa	264	13	children	child	NNS
cord-015935-r2wd1yfa	264	14	with	with	IN
cord-015935-r2wd1yfa	264	15	autism	autism	NN
cord-015935-r2wd1yfa	264	16	from	from	IN
cord-015935-r2wd1yfa	264	17	an	an	DT
cord-015935-r2wd1yfa	264	18	independent	independent	JJ
cord-015935-r2wd1yfa	264	19	laboratory	laboratory	NN
cord-015935-r2wd1yfa	264	20	(	(	-LRB-
cord-015935-r2wd1yfa	264	21	Bailey	Bailey	NNP
cord-015935-r2wd1yfa	264	22	et	et	NNP
cord-015935-r2wd1yfa	264	23	al	al	NNP
cord-015935-r2wd1yfa	264	24	.	.	NNP
cord-015935-r2wd1yfa	264	25	,	,	,
cord-015935-r2wd1yfa	264	26	2008	2008	CD
cord-015935-r2wd1yfa	264	27	)	)	-RRB-
cord-015935-r2wd1yfa	264	28	.	.	.
cord-015935-r2wd1yfa	265	1	High	high	JJ
cord-015935-r2wd1yfa	265	2	levels	level	NNS
cord-015935-r2wd1yfa	265	3	of	of	IN
cord-015935-r2wd1yfa	265	4	sAPPα	sAPPα	NNPS
cord-015935-r2wd1yfa	265	5	imply	imply	VBP
cord-015935-r2wd1yfa	265	6	an	an	DT
cord-015935-r2wd1yfa	265	7	increased	increased	JJ
cord-015935-r2wd1yfa	265	8	α	α	NN
cord-015935-r2wd1yfa	265	9	-	-	HYPH
cord-015935-r2wd1yfa	265	10	secretase	secretase	NNP
cord-015935-r2wd1yfa	265	11	pathway	pathway	NN
cord-015935-r2wd1yfa	265	12	in	in	IN
cord-015935-r2wd1yfa	265	13	autism	autism	NN
cord-015935-r2wd1yfa	265	14	(	(	-LRB-
cord-015935-r2wd1yfa	265	15	anabolic	anabolic	NNP
cord-015935-r2wd1yfa	265	16	)	)	-RRB-
cord-015935-r2wd1yfa	265	17	,	,	,
cord-015935-r2wd1yfa	265	18	opposite	opposite	JJ
cord-015935-r2wd1yfa	265	19	to	to	IN
cord-015935-r2wd1yfa	265	20	what	what	WP
cord-015935-r2wd1yfa	265	21	is	be	VBZ
cord-015935-r2wd1yfa	265	22	seen	see	VBN
cord-015935-r2wd1yfa	265	23	in	in	IN
cord-015935-r2wd1yfa	265	24	Alzheimer	Alzheimer	NNP
cord-015935-r2wd1yfa	265	25	's	's	POS
cord-015935-r2wd1yfa	265	26	disease	disease	NN
cord-015935-r2wd1yfa	265	27	.	.	.
cord-015935-r2wd1yfa	266	1	This	this	DT
cord-015935-r2wd1yfa	266	2	would	would	MD
cord-015935-r2wd1yfa	266	3	be	be	VB
cord-015935-r2wd1yfa	266	4	consistent	consistent	JJ
cord-015935-r2wd1yfa	266	5	with	with	IN
cord-015935-r2wd1yfa	266	6	the	the	DT
cord-015935-r2wd1yfa	266	7	brain	brain	NN
cord-015935-r2wd1yfa	266	8	overgrowth	overgrowth	NN
cord-015935-r2wd1yfa	266	9	hypothesis	hypothesis	NN
cord-015935-r2wd1yfa	266	10	attributed	attribute	VBN
cord-015935-r2wd1yfa	266	11	to	to	IN
cord-015935-r2wd1yfa	266	12	autism	autism	NN
cord-015935-r2wd1yfa	266	13	,	,	,
cord-015935-r2wd1yfa	266	14	in	in	IN
cord-015935-r2wd1yfa	266	15	contrast	contrast	NN
cord-015935-r2wd1yfa	266	16	to	to	IN
cord-015935-r2wd1yfa	266	17	the	the	DT
cord-015935-r2wd1yfa	266	18	brain	brain	NN
cord-015935-r2wd1yfa	266	19	atrophy	atrophy	NN
cord-015935-r2wd1yfa	266	20	seen	see	VBN
cord-015935-r2wd1yfa	266	21	with	with	IN
cord-015935-r2wd1yfa	266	22	the	the	DT
cord-015935-r2wd1yfa	266	23	deposition	deposition	NN
cord-015935-r2wd1yfa	266	24	of	of	IN
cord-015935-r2wd1yfa	266	25	amyloid	amyloid	JJ
cord-015935-r2wd1yfa	266	26	plaque	plaque	NN
cord-015935-r2wd1yfa	266	27	in	in	IN
cord-015935-r2wd1yfa	266	28	Alzheimer	Alzheimer	NNP
cord-015935-r2wd1yfa	266	29	's	's	POS
cord-015935-r2wd1yfa	266	30	disease	disease	NN
cord-015935-r2wd1yfa	266	31	.	.	.
cord-015935-r2wd1yfa	267	1	Coincidentally	coincidentally	RB
cord-015935-r2wd1yfa	267	2	,	,	,
cord-015935-r2wd1yfa	267	3	via	via	IN
cord-015935-r2wd1yfa	267	4	animal	animal	NN
cord-015935-r2wd1yfa	267	5	studies	study	NNS
cord-015935-r2wd1yfa	267	6	,	,	,
cord-015935-r2wd1yfa	267	7	Westmark	Westmark	NNP
cord-015935-r2wd1yfa	267	8	and	and	CC
cord-015935-r2wd1yfa	267	9	Malter	Malter	NNP
cord-015935-r2wd1yfa	267	10	(	(	-LRB-
cord-015935-r2wd1yfa	267	11	2007	2007	CD
cord-015935-r2wd1yfa	267	12	)	)	-RRB-
cord-015935-r2wd1yfa	267	13	concluded	conclude	VBD
cord-015935-r2wd1yfa	267	14	that	that	IN
cord-015935-r2wd1yfa	267	15	FMRP	FMRP	NNP
cord-015935-r2wd1yfa	267	16	binds	bind	VBZ
cord-015935-r2wd1yfa	267	17	to	to	IN
cord-015935-r2wd1yfa	267	18	and	and	CC
cord-015935-r2wd1yfa	267	19	regulates	regulate	VBZ
cord-015935-r2wd1yfa	267	20	translation	translation	NN
cord-015935-r2wd1yfa	267	21	of	of	IN
cord-015935-r2wd1yfa	267	22	APP	app	NN
cord-015935-r2wd1yfa	267	23	mRNA	mrna	NN
cord-015935-r2wd1yfa	267	24	through	through	IN
cord-015935-r2wd1yfa	267	25	mGLuR	mGLuR	NNP
cord-015935-r2wd1yfa	267	26	5	5	CD
cord-015935-r2wd1yfa	267	27	,	,	,
cord-015935-r2wd1yfa	267	28	providing	provide	VBG
cord-015935-r2wd1yfa	267	29	a	a	DT
cord-015935-r2wd1yfa	267	30	potential	potential	JJ
cord-015935-r2wd1yfa	267	31	link	link	NN
cord-015935-r2wd1yfa	267	32	between	between	IN
cord-015935-r2wd1yfa	267	33	neuronal	neuronal	JJ
cord-015935-r2wd1yfa	267	34	proteins	protein	NNS
cord-015935-r2wd1yfa	267	35	associated	associate	VBN
cord-015935-r2wd1yfa	267	36	with	with	IN
cord-015935-r2wd1yfa	267	37	AD	ad	NN
cord-015935-r2wd1yfa	267	38	and	and	CC
cord-015935-r2wd1yfa	267	39	FXS	FXS	NNP
cord-015935-r2wd1yfa	267	40	.	.	.
cord-015935-r2wd1yfa	268	1	By	by	IN
cord-015935-r2wd1yfa	268	2	way	way	NN
cord-015935-r2wd1yfa	268	3	of	of	IN
cord-015935-r2wd1yfa	268	4	mGluR	mGluR	NNP
cord-015935-r2wd1yfa	268	5	5	5	CD
cord-015935-r2wd1yfa	268	6	,	,	,
cord-015935-r2wd1yfa	268	7	FMRP	FMRP	NNP
cord-015935-r2wd1yfa	268	8	provides	provide	VBZ
cord-015935-r2wd1yfa	268	9	the	the	DT
cord-015935-r2wd1yfa	268	10	"	"	``
cord-015935-r2wd1yfa	268	11	brake	brake	NN
cord-015935-r2wd1yfa	268	12	,	,	,
cord-015935-r2wd1yfa	268	13	"	"	''
cord-015935-r2wd1yfa	268	14	which	which	WDT
cord-015935-r2wd1yfa	268	15	if	if	IN
cord-015935-r2wd1yfa	268	16	unchecked	unchecked	JJ
cord-015935-r2wd1yfa	268	17	in	in	IN
cord-015935-r2wd1yfa	268	18	conditions	condition	NNS
cord-015935-r2wd1yfa	268	19	such	such	JJ
cord-015935-r2wd1yfa	268	20	as	as	IN
cord-015935-r2wd1yfa	268	21	FXS	FXS	NNP
cord-015935-r2wd1yfa	268	22	would	would	MD
cord-015935-r2wd1yfa	268	23	favor	favor	VB
cord-015935-r2wd1yfa	268	24	high	high	JJ
cord-015935-r2wd1yfa	268	25	levels	level	NNS
cord-015935-r2wd1yfa	268	26	of	of	IN
cord-015935-r2wd1yfa	268	27	APP	app	NN
cord-015935-r2wd1yfa	268	28	.	.	.
cord-015935-r2wd1yfa	269	1	Further	further	RB
cord-015935-r2wd1yfa	269	2	,	,	,
cord-015935-r2wd1yfa	269	3	high	high	JJ
cord-015935-r2wd1yfa	269	4	levels	level	NNS
cord-015935-r2wd1yfa	269	5	of	of	IN
cord-015935-r2wd1yfa	269	6	APP	app	NN
cord-015935-r2wd1yfa	269	7	have	have	VBP
cord-015935-r2wd1yfa	269	8	been	be	VBN
cord-015935-r2wd1yfa	269	9	found	find	VBN
cord-015935-r2wd1yfa	269	10	in	in	IN
cord-015935-r2wd1yfa	269	11	another	another	DT
cord-015935-r2wd1yfa	269	12	study	study	NN
cord-015935-r2wd1yfa	269	13	of	of	IN
cord-015935-r2wd1yfa	269	14	FMR1	FMR1	NNP
cord-015935-r2wd1yfa	269	15	knockout	knockout	NN
cord-015935-r2wd1yfa	269	16	mice	mouse	NNS
cord-015935-r2wd1yfa	270	1	(	(	-LRB-
cord-015935-r2wd1yfa	270	2	D'Agata	D'Agata	NNP
cord-015935-r2wd1yfa	270	3	et	et	NNP
cord-015935-r2wd1yfa	270	4	al	al	NNP
cord-015935-r2wd1yfa	270	5	.	.	NNP
cord-015935-r2wd1yfa	270	6	,	,	,
cord-015935-r2wd1yfa	270	7	2002	2002	CD
cord-015935-r2wd1yfa	270	8	)	)	-RRB-
cord-015935-r2wd1yfa	270	9	.	.	.
cord-015935-r2wd1yfa	271	1	These	these	DT
cord-015935-r2wd1yfa	271	2	findings	finding	NNS
cord-015935-r2wd1yfa	271	3	have	have	VBP
cord-015935-r2wd1yfa	271	4	led	lead	VBN
cord-015935-r2wd1yfa	271	5	to	to	IN
cord-015935-r2wd1yfa	271	6	enticing	enticing	JJ
cord-015935-r2wd1yfa	271	7	speculation	speculation	NN
cord-015935-r2wd1yfa	271	8	that	that	IN
cord-015935-r2wd1yfa	271	9	the	the	DT
cord-015935-r2wd1yfa	271	10	APP	app	NN
cord-015935-r2wd1yfa	271	11	gene	gene	NN
cord-015935-r2wd1yfa	271	12	may	may	MD
cord-015935-r2wd1yfa	271	13	influence	influence	VB
cord-015935-r2wd1yfa	271	14	several	several	JJ
cord-015935-r2wd1yfa	271	15	neurodevelopmental	neurodevelopmental	JJ
cord-015935-r2wd1yfa	271	16	disorders	disorder	NNS
cord-015935-r2wd1yfa	271	17	across	across	IN
cord-015935-r2wd1yfa	271	18	the	the	DT
cord-015935-r2wd1yfa	271	19	life	life	NN
cord-015935-r2wd1yfa	271	20	span	span	NN
cord-015935-r2wd1yfa	271	21	.	.	.
cord-015935-r2wd1yfa	272	1	Both	both	DT
cord-015935-r2wd1yfa	272	2	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	272	3	inversions	inversion	NNS
cord-015935-r2wd1yfa	272	4	and	and	CC
cord-015935-r2wd1yfa	272	5	translocations	translocation	NNS
cord-015935-r2wd1yfa	272	6	have	have	VBP
cord-015935-r2wd1yfa	272	7	been	be	VBN
cord-015935-r2wd1yfa	272	8	reported	report	VBN
cord-015935-r2wd1yfa	272	9	near	near	IN
cord-015935-r2wd1yfa	272	10	7q31	7q31	CD
cord-015935-r2wd1yfa	272	11	in	in	IN
cord-015935-r2wd1yfa	272	12	boys	boy	NNS
cord-015935-r2wd1yfa	272	13	with	with	IN
cord-015935-r2wd1yfa	272	14	autism	autism	NN
cord-015935-r2wd1yfa	272	15	.	.	.
cord-015935-r2wd1yfa	273	1	One	one	CD
cord-015935-r2wd1yfa	273	2	of	of	IN
cord-015935-r2wd1yfa	273	3	these	these	DT
cord-015935-r2wd1yfa	273	4	translocation	translocation	NN
cord-015935-r2wd1yfa	273	5	breakpoints	breakpoint	NNS
cord-015935-r2wd1yfa	273	6	identified	identify	VBD
cord-015935-r2wd1yfa	273	7	the	the	DT
cord-015935-r2wd1yfa	273	8	deranged	deranged	JJ
cord-015935-r2wd1yfa	273	9	gene	gene	NN
cord-015935-r2wd1yfa	273	10	as	as	IN
cord-015935-r2wd1yfa	273	11	RAY1	RAY1	NNP
cord-015935-r2wd1yfa	273	12	/	/	SYM
cord-015935-r2wd1yfa	273	13	ST7	ST7	NNP
cord-015935-r2wd1yfa	273	14	(	(	-LRB-
cord-015935-r2wd1yfa	273	15	FAM4A1	FAM4A1	NNP
cord-015935-r2wd1yfa	273	16	)	)	-RRB-
cord-015935-r2wd1yfa	273	17	,	,	,
cord-015935-r2wd1yfa	273	18	a	a	DT
cord-015935-r2wd1yfa	273	19	putative	putative	JJ
cord-015935-r2wd1yfa	273	20	tumor	tumor	NN
cord-015935-r2wd1yfa	273	21	suppressor	suppressor	NN
cord-015935-r2wd1yfa	273	22	gene	gene	NN
cord-015935-r2wd1yfa	273	23	(	(	-LRB-
cord-015935-r2wd1yfa	273	24	Vincent	Vincent	NNP
cord-015935-r2wd1yfa	273	25	et	et	NNP
cord-015935-r2wd1yfa	273	26	al	al	NNP
cord-015935-r2wd1yfa	273	27	.	.	NNP
cord-015935-r2wd1yfa	273	28	,	,	,
cord-015935-r2wd1yfa	273	29	2002	2002	CD
cord-015935-r2wd1yfa	273	30	)	)	-RRB-
cord-015935-r2wd1yfa	273	31	,	,	,
cord-015935-r2wd1yfa	273	32	and	and	CC
cord-015935-r2wd1yfa	273	33	work	work	VB
cord-015935-r2wd1yfa	273	34	in	in	IN
cord-015935-r2wd1yfa	273	35	this	this	DT
cord-015935-r2wd1yfa	273	36	region	region	NN
cord-015935-r2wd1yfa	273	37	is	be	VBZ
cord-015935-r2wd1yfa	273	38	ongoing	ongoing	JJ
cord-015935-r2wd1yfa	273	39	.	.	.
cord-015935-r2wd1yfa	274	1	Mutations	mutation	NNS
cord-015935-r2wd1yfa	274	2	leading	lead	VBG
cord-015935-r2wd1yfa	274	3	to	to	IN
cord-015935-r2wd1yfa	274	4	amino	amino	NN
cord-015935-r2wd1yfa	274	5	acid	acid	NN
cord-015935-r2wd1yfa	274	6	changes	change	NNS
cord-015935-r2wd1yfa	274	7	have	have	VBP
cord-015935-r2wd1yfa	274	8	been	be	VBN
cord-015935-r2wd1yfa	274	9	found	find	VBN
cord-015935-r2wd1yfa	274	10	on	on	IN
cord-015935-r2wd1yfa	274	11	the	the	DT
cord-015935-r2wd1yfa	274	12	WNT2	WNT2	NNP
cord-015935-r2wd1yfa	274	13	gene	gene	NN
cord-015935-r2wd1yfa	274	14	on	on	IN
cord-015935-r2wd1yfa	274	15	7q31	7q31	CD
cord-015935-r2wd1yfa	274	16	in	in	IN
cord-015935-r2wd1yfa	274	17	two	two	CD
cord-015935-r2wd1yfa	274	18	families	family	NNS
cord-015935-r2wd1yfa	274	19	with	with	IN
cord-015935-r2wd1yfa	274	20	autism	autism	NN
cord-015935-r2wd1yfa	274	21	,	,	,
cord-015935-r2wd1yfa	274	22	and	and	CC
cord-015935-r2wd1yfa	274	23	one	one	CD
cord-015935-r2wd1yfa	274	24	affected	affected	JJ
cord-015935-r2wd1yfa	274	25	parent	parent	NN
cord-015935-r2wd1yfa	274	26	transmitting	transmit	VBG
cord-015935-r2wd1yfa	274	27	the	the	DT
cord-015935-r2wd1yfa	274	28	mutation	mutation	NN
cord-015935-r2wd1yfa	274	29	to	to	IN
cord-015935-r2wd1yfa	274	30	two	two	CD
cord-015935-r2wd1yfa	274	31	affected	affect	VBN
cord-015935-r2wd1yfa	274	32	children	child	NNS
cord-015935-r2wd1yfa	274	33	(	(	-LRB-
cord-015935-r2wd1yfa	274	34	Li	Li	NNP
cord-015935-r2wd1yfa	274	35	et	et	NNP
cord-015935-r2wd1yfa	274	36	al	al	NNP
cord-015935-r2wd1yfa	274	37	.	.	NNP
cord-015935-r2wd1yfa	274	38	,	,	,
cord-015935-r2wd1yfa	274	39	2004	2004	CD
cord-015935-r2wd1yfa	274	40	;	;	:
cord-015935-r2wd1yfa	274	41	Wassink	Wassink	NNP
cord-015935-r2wd1yfa	274	42	,	,	,
cord-015935-r2wd1yfa	274	43	Brzustowicz	Brzustowicz	NNP
cord-015935-r2wd1yfa	274	44	,	,	,
cord-015935-r2wd1yfa	274	45	Bartlett	Bartlett	NNP
cord-015935-r2wd1yfa	274	46	,	,	,
cord-015935-r2wd1yfa	274	47	&	&	CC
cord-015935-r2wd1yfa	274	48	Szatmari	Szatmari	NNP
cord-015935-r2wd1yfa	274	49	,	,	,
cord-015935-r2wd1yfa	274	50	2004	2004	CD
cord-015935-r2wd1yfa	274	51	)	)	-RRB-
cord-015935-r2wd1yfa	274	52	.	.	.
cord-015935-r2wd1yfa	275	1	The	the	DT
cord-015935-r2wd1yfa	275	2	FOXP2	foxp2	NN
cord-015935-r2wd1yfa	275	3	gene	gene	NN
cord-015935-r2wd1yfa	275	4	on	on	IN
cord-015935-r2wd1yfa	275	5	7q31	7q31	NNP
cord-015935-r2wd1yfa	275	6	was	be	VBD
cord-015935-r2wd1yfa	275	7	found	find	VBN
cord-015935-r2wd1yfa	275	8	to	to	TO
cord-015935-r2wd1yfa	275	9	be	be	VB
cord-015935-r2wd1yfa	275	10	disrupted	disrupt	VBN
cord-015935-r2wd1yfa	275	11	in	in	IN
cord-015935-r2wd1yfa	275	12	one	one	CD
cord-015935-r2wd1yfa	275	13	family	family	NN
cord-015935-r2wd1yfa	275	14	with	with	IN
cord-015935-r2wd1yfa	275	15	an	an	DT
cord-015935-r2wd1yfa	275	16	autosomal	autosomal	JJ
cord-015935-r2wd1yfa	275	17	dominant	dominant	JJ
cord-015935-r2wd1yfa	275	18	form	form	NN
cord-015935-r2wd1yfa	275	19	of	of	IN
cord-015935-r2wd1yfa	275	20	specific	specific	JJ
cord-015935-r2wd1yfa	275	21	language	language	NN
cord-015935-r2wd1yfa	275	22	impairment	impairment	NN
cord-015935-r2wd1yfa	275	23	(	(	-LRB-
cord-015935-r2wd1yfa	275	24	SLI	SLI	NNP
cord-015935-r2wd1yfa	275	25	)	)	-RRB-
cord-015935-r2wd1yfa	276	1	(	(	-LRB-
cord-015935-r2wd1yfa	276	2	Lai	Lai	NNP
cord-015935-r2wd1yfa	276	3	,	,	,
cord-015935-r2wd1yfa	276	4	Fisher	Fisher	NNP
cord-015935-r2wd1yfa	276	5	,	,	,
cord-015935-r2wd1yfa	276	6	Hurst	Hurst	NNP
cord-015935-r2wd1yfa	276	7	,	,	,
cord-015935-r2wd1yfa	276	8	Vargha	Vargha	NNP
cord-015935-r2wd1yfa	276	9	-	-	HYPH
cord-015935-r2wd1yfa	276	10	Khadem	Khadem	NNP
cord-015935-r2wd1yfa	276	11	,	,	,
cord-015935-r2wd1yfa	276	12	&	&	CC
cord-015935-r2wd1yfa	276	13	Monaco	Monaco	NNP
cord-015935-r2wd1yfa	276	14	,	,	,
cord-015935-r2wd1yfa	276	15	2001	2001	CD
cord-015935-r2wd1yfa	276	16	)	)	-RRB-
cord-015935-r2wd1yfa	276	17	,	,	,
cord-015935-r2wd1yfa	276	18	and	and	CC
cord-015935-r2wd1yfa	276	19	this	this	DT
cord-015935-r2wd1yfa	276	20	was	be	VBD
cord-015935-r2wd1yfa	276	21	replicated	replicate	VBN
cord-015935-r2wd1yfa	276	22	in	in	IN
cord-015935-r2wd1yfa	276	23	a	a	DT
cord-015935-r2wd1yfa	276	24	larger	large	JJR
cord-015935-r2wd1yfa	276	25	study	study	NN
cord-015935-r2wd1yfa	276	26	of	of	IN
cord-015935-r2wd1yfa	276	27	SLI	SLI	NNP
cord-015935-r2wd1yfa	276	28	(	(	-LRB-
cord-015935-r2wd1yfa	276	29	O'Brien	O'Brien	NNP
cord-015935-r2wd1yfa	276	30	,	,	,
cord-015935-r2wd1yfa	276	31	Zhang	Zhang	NNP
cord-015935-r2wd1yfa	276	32	,	,	,
cord-015935-r2wd1yfa	276	33	Nishimura	Nishimura	NNP
cord-015935-r2wd1yfa	276	34	,	,	,
cord-015935-r2wd1yfa	276	35	Tomblin	Tomblin	NNP
cord-015935-r2wd1yfa	276	36	,	,	,
cord-015935-r2wd1yfa	276	37	&	&	CC
cord-015935-r2wd1yfa	276	38	Murray	Murray	NNP
cord-015935-r2wd1yfa	276	39	,	,	,
cord-015935-r2wd1yfa	276	40	2003	2003	CD
cord-015935-r2wd1yfa	276	41	)	)	-RRB-
cord-015935-r2wd1yfa	276	42	,	,	,
cord-015935-r2wd1yfa	276	43	although	although	IN
cord-015935-r2wd1yfa	276	44	initial	initial	JJ
cord-015935-r2wd1yfa	276	45	studies	study	NNS
cord-015935-r2wd1yfa	276	46	failed	fail	VBD
cord-015935-r2wd1yfa	276	47	to	to	TO
cord-015935-r2wd1yfa	276	48	associate	associate	VB
cord-015935-r2wd1yfa	276	49	this	this	DT
cord-015935-r2wd1yfa	276	50	with	with	IN
cord-015935-r2wd1yfa	276	51	autism	autism	NN
cord-015935-r2wd1yfa	276	52	(	(	-LRB-
cord-015935-r2wd1yfa	276	53	Newbury	Newbury	NNP
cord-015935-r2wd1yfa	276	54	et	et	NNP
cord-015935-r2wd1yfa	276	55	al	al	NNP
cord-015935-r2wd1yfa	276	56	.	.	NNP
cord-015935-r2wd1yfa	276	57	,	,	,
cord-015935-r2wd1yfa	276	58	2002	2002	CD
cord-015935-r2wd1yfa	276	59	;	;	:
cord-015935-r2wd1yfa	276	60	Wassink	Wassink	NNP
cord-015935-r2wd1yfa	276	61	et	et	NNP
cord-015935-r2wd1yfa	276	62	al	al	NNP
cord-015935-r2wd1yfa	276	63	.	.	NNP
cord-015935-r2wd1yfa	276	64	,	,	,
cord-015935-r2wd1yfa	276	65	2001	2001	CD
cord-015935-r2wd1yfa	276	66	)	)	-RRB-
cord-015935-r2wd1yfa	276	67	.	.	.
cord-015935-r2wd1yfa	277	1	Recently	recently	RB
cord-015935-r2wd1yfa	277	2	,	,	,
cord-015935-r2wd1yfa	277	3	FOXP2	FOXP2	NNP
cord-015935-r2wd1yfa	277	4	differences	difference	NNS
cord-015935-r2wd1yfa	277	5	in	in	IN
cord-015935-r2wd1yfa	277	6	gene	gene	NN
cord-015935-r2wd1yfa	277	7	expression	expression	NN
cord-015935-r2wd1yfa	277	8	were	be	VBD
cord-015935-r2wd1yfa	277	9	found	find	VBN
cord-015935-r2wd1yfa	277	10	between	between	IN
cord-015935-r2wd1yfa	277	11	chimp	chimp	NN
cord-015935-r2wd1yfa	277	12	and	and	CC
cord-015935-r2wd1yfa	277	13	human	human	JJ
cord-015935-r2wd1yfa	277	14	cell	cell	NN
cord-015935-r2wd1yfa	277	15	cultures	culture	NNS
cord-015935-r2wd1yfa	277	16	.	.	.
cord-015935-r2wd1yfa	278	1	Compared	compare	VBN
cord-015935-r2wd1yfa	278	2	to	to	IN
cord-015935-r2wd1yfa	278	3	chimps	chimp	NNS
cord-015935-r2wd1yfa	278	4	,	,	,
cord-015935-r2wd1yfa	278	5	in	in	IN
cord-015935-r2wd1yfa	278	6	human	human	JJ
cord-015935-r2wd1yfa	278	7	culture	culture	NN
cord-015935-r2wd1yfa	278	8	,	,	,
cord-015935-r2wd1yfa	278	9	the	the	DT
cord-015935-r2wd1yfa	278	10	FOXP2	foxp2	NN
cord-015935-r2wd1yfa	278	11	gene	gene	NN
cord-015935-r2wd1yfa	278	12	affected	affect	VBD
cord-015935-r2wd1yfa	278	13	transcription	transcription	NN
cord-015935-r2wd1yfa	278	14	upregulation	upregulation	NN
cord-015935-r2wd1yfa	278	15	in	in	IN
cord-015935-r2wd1yfa	278	16	61	61	CD
cord-015935-r2wd1yfa	278	17	genes	gene	NNS
cord-015935-r2wd1yfa	278	18	and	and	CC
cord-015935-r2wd1yfa	278	19	downregulation	downregulation	NN
cord-015935-r2wd1yfa	278	20	in	in	IN
cord-015935-r2wd1yfa	278	21	55	55	CD
cord-015935-r2wd1yfa	278	22	genes	gene	NNS
cord-015935-r2wd1yfa	278	23	.	.	.
cord-015935-r2wd1yfa	279	1	Further	further	RB
cord-015935-r2wd1yfa	279	2	,	,	,
cord-015935-r2wd1yfa	279	3	the	the	DT
cord-015935-r2wd1yfa	279	4	FOXP2	foxp2	NN
cord-015935-r2wd1yfa	279	5	gene	gene	NN
cord-015935-r2wd1yfa	279	6	was	be	VBD
cord-015935-r2wd1yfa	279	7	shown	show	VBN
cord-015935-r2wd1yfa	279	8	to	to	TO
cord-015935-r2wd1yfa	279	9	regulate	regulate	VB
cord-015935-r2wd1yfa	279	10	downstream	downstream	JJ
cord-015935-r2wd1yfa	279	11	effects	effect	NNS
cord-015935-r2wd1yfa	279	12	involving	involve	VBG
cord-015935-r2wd1yfa	279	13	cerebellar	cerebellar	JJ
cord-015935-r2wd1yfa	279	14	motor	motor	NN
cord-015935-r2wd1yfa	279	15	function	function	NN
cord-015935-r2wd1yfa	279	16	,	,	,
cord-015935-r2wd1yfa	279	17	craniofacial	craniofacial	JJ
cord-015935-r2wd1yfa	279	18	formation	formation	NN
cord-015935-r2wd1yfa	279	19	,	,	,
cord-015935-r2wd1yfa	279	20	and	and	CC
cord-015935-r2wd1yfa	279	21	cartilage	cartilage	NN
cord-015935-r2wd1yfa	279	22	and	and	CC
cord-015935-r2wd1yfa	279	23	connective	connective	JJ
cord-015935-r2wd1yfa	279	24	tissue	tissue	NN
cord-015935-r2wd1yfa	279	25	formation	formation	NN
cord-015935-r2wd1yfa	279	26	required	require	VBN
cord-015935-r2wd1yfa	279	27	for	for	IN
cord-015935-r2wd1yfa	279	28	expressive	expressive	JJ
cord-015935-r2wd1yfa	279	29	language	language	NN
cord-015935-r2wd1yfa	279	30	.	.	.
cord-015935-r2wd1yfa	280	1	As	as	IN
cord-015935-r2wd1yfa	280	2	discussed	discuss	VBN
cord-015935-r2wd1yfa	280	3	in	in	IN
cord-015935-r2wd1yfa	280	4	section	section	NN
cord-015935-r2wd1yfa	280	5	"	"	``
cord-015935-r2wd1yfa	280	6	Endophenotype	Endophenotype	NNP
cord-015935-r2wd1yfa	280	7	,	,	,
cord-015935-r2wd1yfa	280	8	"	"	''
cord-015935-r2wd1yfa	280	9	there	there	EX
cord-015935-r2wd1yfa	280	10	is	be	VBZ
cord-015935-r2wd1yfa	280	11	a	a	DT
cord-015935-r2wd1yfa	280	12	suspected	suspect	VBN
cord-015935-r2wd1yfa	280	13	association	association	NN
cord-015935-r2wd1yfa	280	14	between	between	IN
cord-015935-r2wd1yfa	280	15	the	the	DT
cord-015935-r2wd1yfa	280	16	chromosome	chromosome	NN
cord-015935-r2wd1yfa	280	17	7q	7q	CD
cord-015935-r2wd1yfa	280	18	region	region	NN
cord-015935-r2wd1yfa	280	19	and	and	CC
cord-015935-r2wd1yfa	280	20	speech	speech	NN
cord-015935-r2wd1yfa	280	21	abnormality	abnormality	NN
cord-015935-r2wd1yfa	280	22	seen	see	VBN
cord-015935-r2wd1yfa	280	23	in	in	IN
cord-015935-r2wd1yfa	280	24	autism	autism	NN
cord-015935-r2wd1yfa	280	25	.	.	.
cord-015935-r2wd1yfa	281	1	The	the	DT
cord-015935-r2wd1yfa	281	2	RELN	RELN	NNP
cord-015935-r2wd1yfa	281	3	gene	gene	NN
cord-015935-r2wd1yfa	281	4	maps	map	NNS
cord-015935-r2wd1yfa	281	5	to	to	TO
cord-015935-r2wd1yfa	281	6	chromosome	chromosome	VB
cord-015935-r2wd1yfa	281	7	7q22	7q22	CD
cord-015935-r2wd1yfa	281	8	.	.	.
cord-015935-r2wd1yfa	282	1	This	this	DT
cord-015935-r2wd1yfa	282	2	gene	gene	NN
cord-015935-r2wd1yfa	282	3	encodes	encode	VBZ
cord-015935-r2wd1yfa	282	4	a	a	DT
cord-015935-r2wd1yfa	282	5	protein	protein	NN
cord-015935-r2wd1yfa	282	6	that	that	WDT
cord-015935-r2wd1yfa	282	7	controls	control	VBZ
cord-015935-r2wd1yfa	282	8	intercellular	intercellular	JJ
cord-015935-r2wd1yfa	282	9	interactions	interaction	NNS
cord-015935-r2wd1yfa	282	10	involved	involve	VBN
cord-015935-r2wd1yfa	282	11	in	in	IN
cord-015935-r2wd1yfa	282	12	neuronal	neuronal	JJ
cord-015935-r2wd1yfa	282	13	migration	migration	NN
cord-015935-r2wd1yfa	282	14	and	and	CC
cord-015935-r2wd1yfa	282	15	positioning	positioning	NN
cord-015935-r2wd1yfa	282	16	in	in	IN
cord-015935-r2wd1yfa	282	17	brain	brain	NN
cord-015935-r2wd1yfa	282	18	development	development	NN
cord-015935-r2wd1yfa	282	19	.	.	.
cord-015935-r2wd1yfa	283	1	A	a	DT
cord-015935-r2wd1yfa	283	2	large	large	JJ
cord-015935-r2wd1yfa	283	3	polymorphic	polymorphic	JJ
cord-015935-r2wd1yfa	283	4	trinucleotide	trinucleotide	NN
cord-015935-r2wd1yfa	283	5	repeat	repeat	NN
cord-015935-r2wd1yfa	283	6	in	in	IN
cord-015935-r2wd1yfa	283	7	the	the	DT
cord-015935-r2wd1yfa	283	8	5	5	CD
cord-015935-r2wd1yfa	283	9	-YTR	-ytr	NN
cord-015935-r2wd1yfa	283	10	of	of	IN
cord-015935-r2wd1yfa	283	11	the	the	DT
cord-015935-r2wd1yfa	283	12	RELN	RELN	NNP
cord-015935-r2wd1yfa	283	13	gene	gene	NN
cord-015935-r2wd1yfa	283	14	has	have	VBZ
cord-015935-r2wd1yfa	283	15	been	be	VBN
cord-015935-r2wd1yfa	283	16	implicated	implicate	VBN
cord-015935-r2wd1yfa	283	17	in	in	IN
cord-015935-r2wd1yfa	283	18	autism	autism	NN
cord-015935-r2wd1yfa	283	19	in	in	IN
cord-015935-r2wd1yfa	283	20	several	several	JJ
cord-015935-r2wd1yfa	283	21	studies	study	NNS
cord-015935-r2wd1yfa	283	22	(	(	-LRB-
cord-015935-r2wd1yfa	283	23	Ashley	Ashley	NNP
cord-015935-r2wd1yfa	283	24	-	-	HYPH
cord-015935-r2wd1yfa	283	25	Koch	Koch	NNP
cord-015935-r2wd1yfa	283	26	et	et	NNP
cord-015935-r2wd1yfa	283	27	al	al	NNP
cord-015935-r2wd1yfa	283	28	.	.	NNP
cord-015935-r2wd1yfa	283	29	,	,	,
cord-015935-r2wd1yfa	283	30	2007	2007	CD
cord-015935-r2wd1yfa	283	31	;	;	:
cord-015935-r2wd1yfa	283	32	Persico	Persico	NNP
cord-015935-r2wd1yfa	283	33	et	et	NNP
cord-015935-r2wd1yfa	283	34	al	al	NNP
cord-015935-r2wd1yfa	283	35	.	.	.
cord-015935-r2wd1yfa	284	1	,	,	,
cord-015935-r2wd1yfa	284	2	2002	2002	CD
cord-015935-r2wd1yfa	284	3	;	;	:
cord-015935-r2wd1yfa	284	4	Zhang	Zhang	NNP
cord-015935-r2wd1yfa	284	5	et	et	NNP
cord-015935-r2wd1yfa	284	6	al	al	NNP
cord-015935-r2wd1yfa	284	7	.	.	NNP
cord-015935-r2wd1yfa	284	8	,	,	,
cord-015935-r2wd1yfa	284	9	2002	2002	CD
cord-015935-r2wd1yfa	284	10	)	)	-RRB-
cord-015935-r2wd1yfa	284	11	.	.	.
cord-015935-r2wd1yfa	285	1	Further	further	JJ
cord-015935-r2wd1yfa	285	2	support	support	NN
cord-015935-r2wd1yfa	285	3	for	for	IN
cord-015935-r2wd1yfa	285	4	this	this	DT
cord-015935-r2wd1yfa	285	5	candidate	candidate	NN
cord-015935-r2wd1yfa	285	6	gene	gene	NN
cord-015935-r2wd1yfa	285	7	comes	come	VBZ
cord-015935-r2wd1yfa	285	8	from	from	IN
cord-015935-r2wd1yfa	285	9	the	the	DT
cord-015935-r2wd1yfa	285	10	RELN	RELN	NNP
cord-015935-r2wd1yfa	285	11	mouse	mouse	NN
cord-015935-r2wd1yfa	285	12	model	model	NN
cord-015935-r2wd1yfa	285	13	which	which	WDT
cord-015935-r2wd1yfa	285	14	carries	carry	VBZ
cord-015935-r2wd1yfa	285	15	a	a	DT
cord-015935-r2wd1yfa	285	16	large	large	JJ
cord-015935-r2wd1yfa	285	17	deletion	deletion	NN
cord-015935-r2wd1yfa	285	18	in	in	IN
cord-015935-r2wd1yfa	285	19	RELN	RELN	NNP
cord-015935-r2wd1yfa	285	20	and	and	CC
cord-015935-r2wd1yfa	285	21	shows	show	VBZ
cord-015935-r2wd1yfa	285	22	atypical	atypical	JJ
cord-015935-r2wd1yfa	285	23	cortical	cortical	JJ
cord-015935-r2wd1yfa	285	24	organization	organization	NN
cord-015935-r2wd1yfa	285	25	similar	similar	JJ
cord-015935-r2wd1yfa	285	26	to	to	IN
cord-015935-r2wd1yfa	285	27	cytoarchitectural	cytoarchitectural	JJ
cord-015935-r2wd1yfa	285	28	pathological	pathological	JJ
cord-015935-r2wd1yfa	285	29	anomalies	anomaly	NNS
cord-015935-r2wd1yfa	285	30	reported	report	VBN
cord-015935-r2wd1yfa	285	31	in	in	IN
cord-015935-r2wd1yfa	285	32	the	the	DT
cord-015935-r2wd1yfa	285	33	brains	brain	NNS
cord-015935-r2wd1yfa	285	34	of	of	IN
cord-015935-r2wd1yfa	285	35	individuals	individual	NNS
cord-015935-r2wd1yfa	285	36	with	with	IN
cord-015935-r2wd1yfa	285	37	autism	autism	NN
cord-015935-r2wd1yfa	285	38	(	(	-LRB-
cord-015935-r2wd1yfa	285	39	Bailey	Bailey	NNP
cord-015935-r2wd1yfa	285	40	et	et	NNP
cord-015935-r2wd1yfa	285	41	al	al	NNP
cord-015935-r2wd1yfa	285	42	.	.	NNP
cord-015935-r2wd1yfa	285	43	,	,	,
cord-015935-r2wd1yfa	285	44	2008	2008	CD
cord-015935-r2wd1yfa	285	45	)	)	-RRB-
cord-015935-r2wd1yfa	285	46	.	.	.
cord-015935-r2wd1yfa	286	1	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	286	2	is	be	VBZ
cord-015935-r2wd1yfa	286	3	a	a	DT
cord-015935-r2wd1yfa	286	4	tumor	tumor	NN
cord-015935-r2wd1yfa	286	5	suppressor	suppressor	NN
cord-015935-r2wd1yfa	286	6	gene	gene	NN
cord-015935-r2wd1yfa	286	7	located	locate	VBN
cord-015935-r2wd1yfa	286	8	on	on	IN
cord-015935-r2wd1yfa	286	9	chromosome	chromosome	NN
cord-015935-r2wd1yfa	286	10	10q23	10q23	CD
cord-015935-r2wd1yfa	286	11	.	.	.
cord-015935-r2wd1yfa	287	1	This	this	DT
cord-015935-r2wd1yfa	287	2	gene	gene	NN
cord-015935-r2wd1yfa	287	3	influences	influence	VBZ
cord-015935-r2wd1yfa	287	4	the	the	DT
cord-015935-r2wd1yfa	287	5	cell	cell	NN
cord-015935-r2wd1yfa	287	6	-	-	HYPH
cord-015935-r2wd1yfa	287	7	cell	cell	NN
cord-015935-r2wd1yfa	287	8	arrest	arrest	NN
cord-015935-r2wd1yfa	287	9	cycle	cycle	NN
cord-015935-r2wd1yfa	287	10	and	and	CC
cord-015935-r2wd1yfa	287	11	apoptosis	apoptosis	NN
cord-015935-r2wd1yfa	287	12	or	or	CC
cord-015935-r2wd1yfa	287	13	programmed	program	VBN
cord-015935-r2wd1yfa	287	14	cell	cell	NN
cord-015935-r2wd1yfa	287	15	death	death	NN
cord-015935-r2wd1yfa	287	16	(	(	-LRB-
cord-015935-r2wd1yfa	287	17	Lintas	Lintas	NNP
cord-015935-r2wd1yfa	287	18	&	&	CC
cord-015935-r2wd1yfa	287	19	Persico	Persico	NNP
cord-015935-r2wd1yfa	287	20	,	,	,
cord-015935-r2wd1yfa	287	21	2009	2009	CD
cord-015935-r2wd1yfa	287	22	)	)	-RRB-
cord-015935-r2wd1yfa	287	23	.	.	.
cord-015935-r2wd1yfa	288	1	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	288	2	inactivation	inactivation	NN
cord-015935-r2wd1yfa	288	3	causes	cause	VBZ
cord-015935-r2wd1yfa	288	4	excessive	excessive	JJ
cord-015935-r2wd1yfa	288	5	growth	growth	NN
cord-015935-r2wd1yfa	288	6	of	of	IN
cord-015935-r2wd1yfa	288	7	dendrites	dendrite	NNS
cord-015935-r2wd1yfa	288	8	and	and	CC
cord-015935-r2wd1yfa	288	9	axons	axon	NNS
cord-015935-r2wd1yfa	288	10	,	,	,
cord-015935-r2wd1yfa	288	11	with	with	IN
cord-015935-r2wd1yfa	288	12	an	an	DT
cord-015935-r2wd1yfa	288	13	increased	increase	VBN
cord-015935-r2wd1yfa	288	14	number	number	NN
cord-015935-r2wd1yfa	288	15	of	of	IN
cord-015935-r2wd1yfa	288	16	synapses	synapsis	NNS
cord-015935-r2wd1yfa	288	17	(	(	-LRB-
cord-015935-r2wd1yfa	288	18	Kwon	Kwon	NNP
cord-015935-r2wd1yfa	288	19	et	et	NNP
cord-015935-r2wd1yfa	288	20	al	al	NNP
cord-015935-r2wd1yfa	288	21	.	.	NNP
cord-015935-r2wd1yfa	288	22	,	,	,
cord-015935-r2wd1yfa	288	23	2006	2006	CD
cord-015935-r2wd1yfa	288	24	)	)	-RRB-
cord-015935-r2wd1yfa	288	25	.	.	.
cord-015935-r2wd1yfa	289	1	Mutations	mutation	NNS
cord-015935-r2wd1yfa	289	2	in	in	IN
cord-015935-r2wd1yfa	289	3	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	289	4	cause	cause	VBP
cord-015935-r2wd1yfa	289	5	Cowden	Cowden	NNP
cord-015935-r2wd1yfa	289	6	's	's	POS
cord-015935-r2wd1yfa	289	7	syndrome	syndrome	NN
cord-015935-r2wd1yfa	289	8	(	(	-LRB-
cord-015935-r2wd1yfa	289	9	macrocephaly	macrocephaly	NNP
cord-015935-r2wd1yfa	289	10	,	,	,
cord-015935-r2wd1yfa	289	11	hamartomas	hamartomas	NNP
cord-015935-r2wd1yfa	289	12	,	,	,
cord-015935-r2wd1yfa	289	13	and	and	CC
cord-015935-r2wd1yfa	289	14	autism	autism	NN
cord-015935-r2wd1yfa	289	15	)	)	-RRB-
cord-015935-r2wd1yfa	289	16	.	.	.
cord-015935-r2wd1yfa	290	1	This	this	DT
cord-015935-r2wd1yfa	290	2	gene	gene	NN
cord-015935-r2wd1yfa	290	3	has	have	VBZ
cord-015935-r2wd1yfa	290	4	been	be	VBN
cord-015935-r2wd1yfa	290	5	of	of	IN
cord-015935-r2wd1yfa	290	6	interest	interest	NN
cord-015935-r2wd1yfa	290	7	to	to	IN
cord-015935-r2wd1yfa	290	8	autism	autism	NN
cord-015935-r2wd1yfa	290	9	researchers	researcher	NNS
cord-015935-r2wd1yfa	290	10	as	as	IN
cord-015935-r2wd1yfa	290	11	macrocephaly	macrocephaly	NNP
cord-015935-r2wd1yfa	290	12	has	have	VBZ
cord-015935-r2wd1yfa	290	13	been	be	VBN
cord-015935-r2wd1yfa	290	14	considered	consider	VBN
cord-015935-r2wd1yfa	290	15	to	to	TO
cord-015935-r2wd1yfa	290	16	be	be	VB
cord-015935-r2wd1yfa	290	17	one	one	CD
cord-015935-r2wd1yfa	290	18	of	of	IN
cord-015935-r2wd1yfa	290	19	the	the	DT
cord-015935-r2wd1yfa	290	20	"	"	``
cord-015935-r2wd1yfa	290	21	most	most	RBS
cord-015935-r2wd1yfa	290	22	widely	widely	RB
cord-015935-r2wd1yfa	290	23	replicated	replicate	VBN
cord-015935-r2wd1yfa	290	24	biological	biological	JJ
cord-015935-r2wd1yfa	290	25	findings	finding	NNS
cord-015935-r2wd1yfa	290	26	in	in	IN
cord-015935-r2wd1yfa	290	27	autism	autism	NN
cord-015935-r2wd1yfa	290	28	"	"	``
cord-015935-r2wd1yfa	290	29	affecting	affect	VBG
cord-015935-r2wd1yfa	290	30	up	up	IN
cord-015935-r2wd1yfa	290	31	to	to	TO
cord-015935-r2wd1yfa	290	32	20	20	CD
cord-015935-r2wd1yfa	290	33	%	%	NN
cord-015935-r2wd1yfa	290	34	of	of	IN
cord-015935-r2wd1yfa	290	35	all	all	DT
cord-015935-r2wd1yfa	290	36	children	child	NNS
cord-015935-r2wd1yfa	290	37	with	with	IN
cord-015935-r2wd1yfa	290	38	the	the	DT
cord-015935-r2wd1yfa	290	39	condition	condition	NN
cord-015935-r2wd1yfa	290	40	(	(	-LRB-
cord-015935-r2wd1yfa	290	41	McCaffery	McCaffery	NNP
cord-015935-r2wd1yfa	290	42	&	&	CC
cord-015935-r2wd1yfa	290	43	Deutsch	Deutsch	NNP
cord-015935-r2wd1yfa	290	44	,	,	,
cord-015935-r2wd1yfa	290	45	2005	2005	CD
cord-015935-r2wd1yfa	290	46	)	)	-RRB-
cord-015935-r2wd1yfa	290	47	.	.	.
cord-015935-r2wd1yfa	291	1	Butler	Butler	NNP
cord-015935-r2wd1yfa	291	2	et	et	NNP
cord-015935-r2wd1yfa	291	3	al	al	NNP
cord-015935-r2wd1yfa	291	4	.	.	.
cord-015935-r2wd1yfa	292	1	(	(	-LRB-
cord-015935-r2wd1yfa	292	2	2005	2005	CD
cord-015935-r2wd1yfa	292	3	)	)	-RRB-
cord-015935-r2wd1yfa	292	4	examined	examine	VBD
cord-015935-r2wd1yfa	292	5	the	the	DT
cord-015935-r2wd1yfa	292	6	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	292	7	gene	gene	NN
cord-015935-r2wd1yfa	292	8	in	in	IN
cord-015935-r2wd1yfa	292	9	18	18	CD
cord-015935-r2wd1yfa	292	10	individuals	individual	NNS
cord-015935-r2wd1yfa	292	11	with	with	IN
cord-015935-r2wd1yfa	292	12	autism	autism	NN
cord-015935-r2wd1yfa	292	13	and	and	CC
cord-015935-r2wd1yfa	292	14	macrocephaly	macrocephaly	NNP
cord-015935-r2wd1yfa	292	15	.	.	.
cord-015935-r2wd1yfa	293	1	They	-PRON-	PRP
cord-015935-r2wd1yfa	293	2	discovered	discover	VBD
cord-015935-r2wd1yfa	293	3	three	three	CD
cord-015935-r2wd1yfa	293	4	with	with	IN
cord-015935-r2wd1yfa	293	5	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	293	6	missense	missense	NN
cord-015935-r2wd1yfa	293	7	mutations	mutation	NNS
cord-015935-r2wd1yfa	293	8	.	.	.
cord-015935-r2wd1yfa	294	1	Others	other	NNS
cord-015935-r2wd1yfa	294	2	have	have	VBP
cord-015935-r2wd1yfa	294	3	found	find	VBN
cord-015935-r2wd1yfa	294	4	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	294	5	mutations	mutation	NNS
cord-015935-r2wd1yfa	294	6	in	in	IN
cord-015935-r2wd1yfa	294	7	macrocephalic	macrocephalic	JJ
cord-015935-r2wd1yfa	294	8	patients	patient	NNS
cord-015935-r2wd1yfa	294	9	with	with	IN
cord-015935-r2wd1yfa	294	10	autism	autism	NN
cord-015935-r2wd1yfa	294	11	(	(	-LRB-
cord-015935-r2wd1yfa	294	12	Herman	Herman	NNP
cord-015935-r2wd1yfa	294	13	et	et	NNP
cord-015935-r2wd1yfa	294	14	al	al	NNP
cord-015935-r2wd1yfa	294	15	.	.	.
cord-015935-r2wd1yfa	295	1	,	,	,
cord-015935-r2wd1yfa	295	2	2007a	2007a	CD
cord-015935-r2wd1yfa	296	1	(	(	-LRB-
cord-015935-r2wd1yfa	296	2	Herman	Herman	NNP
cord-015935-r2wd1yfa	296	3	et	et	NNP
cord-015935-r2wd1yfa	296	4	al	al	NNP
cord-015935-r2wd1yfa	296	5	.	.	.
cord-015935-r2wd1yfa	297	1	,	,	,
cord-015935-r2wd1yfa	297	2	,	,	,
cord-015935-r2wd1yfa	297	3	2007b	2007b	CD
cord-015935-r2wd1yfa	297	4	.	.	.
cord-015935-r2wd1yfa	298	1	Cytogenic	Cytogenic	NNP
cord-015935-r2wd1yfa	298	2	abnormalities	abnormality	NNS
cord-015935-r2wd1yfa	298	3	have	have	VBP
cord-015935-r2wd1yfa	298	4	included	include	VBN
cord-015935-r2wd1yfa	298	5	deletions	deletion	NNS
cord-015935-r2wd1yfa	298	6	and	and	CC
cord-015935-r2wd1yfa	298	7	duplications	duplication	NNS
cord-015935-r2wd1yfa	298	8	involving	involve	VBG
cord-015935-r2wd1yfa	298	9	2q37	2q37	CD
cord-015935-r2wd1yfa	298	10	,	,	,
cord-015935-r2wd1yfa	298	11	22	22	CD
cord-015935-r2wd1yfa	298	12	q13	q13	NN
cord-015935-r2wd1yfa	298	13	,	,	,
cord-015935-r2wd1yfa	298	14	22q11	22q11	CD
cord-015935-r2wd1yfa	298	15	,	,	,
cord-015935-r2wd1yfa	298	16	17p11	17p11	CD
cord-015935-r2wd1yfa	298	17	,	,	,
cord-015935-r2wd1yfa	298	18	16p11.2,18q	16p11.2,18q	CD
cord-015935-r2wd1yfa	298	19	,	,	,
cord-015935-r2wd1yfa	298	20	Xp	Xp	NNP
cord-015935-r2wd1yfa	298	21	,	,	,
cord-015935-r2wd1yfa	298	22	and	and	CC
cord-015935-r2wd1yfa	298	23	sex	sex	NN
cord-015935-r2wd1yfa	298	24	chromosome	chromosome	NN
cord-015935-r2wd1yfa	298	25	aneuploidies	aneuploidy	NNS
cord-015935-r2wd1yfa	298	26	(	(	-LRB-
cord-015935-r2wd1yfa	298	27	47	47	CD
cord-015935-r2wd1yfa	298	28	,	,	,
cord-015935-r2wd1yfa	298	29	XYY	XYY	NNP
cord-015935-r2wd1yfa	298	30	and	and	CC
cord-015935-r2wd1yfa	298	31	45	45	CD
cord-015935-r2wd1yfa	298	32	,	,	,
cord-015935-r2wd1yfa	298	33	X/46	X/46	NNP
cord-015935-r2wd1yfa	298	34	,	,	,
cord-015935-r2wd1yfa	298	35	and	and	CC
cord-015935-r2wd1yfa	298	36	XY	XY	NNP
cord-015935-r2wd1yfa	298	37	mosaicism	mosaicism	NN
cord-015935-r2wd1yfa	298	38	)	)	-RRB-
cord-015935-r2wd1yfa	299	1	(	(	-LRB-
cord-015935-r2wd1yfa	299	2	Costa	Costa	NNP
cord-015935-r2wd1yfa	299	3	e	e	NNP
cord-015935-r2wd1yfa	299	4	Silva	Silva	NNP
cord-015935-r2wd1yfa	299	5	,	,	,
cord-015935-r2wd1yfa	299	6	2008	2008	CD
cord-015935-r2wd1yfa	299	7	;	;	:
cord-015935-r2wd1yfa	299	8	Sykes	Sykes	NNP
cord-015935-r2wd1yfa	299	9	&	&	CC
cord-015935-r2wd1yfa	299	10	Lamb	Lamb	NNP
cord-015935-r2wd1yfa	299	11	,	,	,
cord-015935-r2wd1yfa	299	12	2007	2007	CD
cord-015935-r2wd1yfa	299	13	)	)	-RRB-
cord-015935-r2wd1yfa	299	14	.	.	.
cord-015935-r2wd1yfa	300	1	These	these	DT
cord-015935-r2wd1yfa	300	2	genetic	genetic	JJ
cord-015935-r2wd1yfa	300	3	findings	finding	NNS
cord-015935-r2wd1yfa	300	4	have	have	VBP
cord-015935-r2wd1yfa	300	5	generated	generate	VBN
cord-015935-r2wd1yfa	300	6	interest	interest	NN
cord-015935-r2wd1yfa	300	7	in	in	IN
cord-015935-r2wd1yfa	300	8	testing	test	VBG
cord-015935-r2wd1yfa	300	9	the	the	DT
cord-015935-r2wd1yfa	300	10	association	association	NN
cord-015935-r2wd1yfa	300	11	of	of	IN
cord-015935-r2wd1yfa	300	12	a	a	DT
cord-015935-r2wd1yfa	300	13	number	number	NN
cord-015935-r2wd1yfa	300	14	of	of	IN
cord-015935-r2wd1yfa	300	15	candidate	candidate	NN
cord-015935-r2wd1yfa	300	16	genes	gene	NNS
cord-015935-r2wd1yfa	300	17	in	in	IN
cord-015935-r2wd1yfa	300	18	these	these	DT
cord-015935-r2wd1yfa	300	19	regions	region	NNS
cord-015935-r2wd1yfa	300	20	via	via	IN
cord-015935-r2wd1yfa	300	21	linkage	linkage	NN
cord-015935-r2wd1yfa	300	22	and	and	CC
cord-015935-r2wd1yfa	300	23	animal	animal	NN
cord-015935-r2wd1yfa	300	24	studies	study	NNS
cord-015935-r2wd1yfa	300	25	.	.	.
cord-015935-r2wd1yfa	301	1	Accumulating	accumulate	VBG
cord-015935-r2wd1yfa	301	2	evidence	evidence	NN
cord-015935-r2wd1yfa	301	3	points	point	NNS
cord-015935-r2wd1yfa	301	4	to	to	IN
cord-015935-r2wd1yfa	301	5	the	the	DT
cord-015935-r2wd1yfa	301	6	involvement	involvement	NN
cord-015935-r2wd1yfa	301	7	of	of	IN
cord-015935-r2wd1yfa	301	8	three	three	CD
cord-015935-r2wd1yfa	301	9	genes	gene	NNS
cord-015935-r2wd1yfa	301	10	(	(	-LRB-
cord-015935-r2wd1yfa	301	11	neuroligin	neuroligin	NNP
cord-015935-r2wd1yfa	301	12	,	,	,
cord-015935-r2wd1yfa	301	13	SHANK3	SHANK3	NNP
cord-015935-r2wd1yfa	301	14	,	,	,
cord-015935-r2wd1yfa	301	15	and	and	CC
cord-015935-r2wd1yfa	301	16	neurexin	neurexin	NNP
cord-015935-r2wd1yfa	301	17	)	)	-RRB-
cord-015935-r2wd1yfa	301	18	in	in	IN
cord-015935-r2wd1yfa	301	19	the	the	DT
cord-015935-r2wd1yfa	301	20	synapse	synapse	NN
cord-015935-r2wd1yfa	301	21	formation	formation	NN
cord-015935-r2wd1yfa	301	22	of	of	IN
cord-015935-r2wd1yfa	301	23	glutamate	glutamate	NN
cord-015935-r2wd1yfa	301	24	neurons	neuron	NNS
cord-015935-r2wd1yfa	301	25	.	.	.
cord-015935-r2wd1yfa	302	1	Glutamate	glutamate	NN
cord-015935-r2wd1yfa	302	2	is	be	VBZ
cord-015935-r2wd1yfa	302	3	an	an	DT
cord-015935-r2wd1yfa	302	4	excitatory	excitatory	JJ
cord-015935-r2wd1yfa	302	5	neurotransmitter	neurotransmitter	NN
cord-015935-r2wd1yfa	302	6	and	and	CC
cord-015935-r2wd1yfa	302	7	aberrant	aberrant	JJ
cord-015935-r2wd1yfa	302	8	glutamate	glutamate	NN
cord-015935-r2wd1yfa	302	9	function	function	NN
cord-015935-r2wd1yfa	302	10	has	have	VBZ
cord-015935-r2wd1yfa	302	11	long	long	RB
cord-015935-r2wd1yfa	302	12	been	be	VBN
cord-015935-r2wd1yfa	302	13	suspected	suspect	VBN
cord-015935-r2wd1yfa	302	14	to	to	TO
cord-015935-r2wd1yfa	302	15	contribute	contribute	VB
cord-015935-r2wd1yfa	302	16	to	to	IN
cord-015935-r2wd1yfa	302	17	autism	autism	NN
cord-015935-r2wd1yfa	302	18	.	.	.
cord-015935-r2wd1yfa	303	1	Neuroligins	neuroligin	NNS
cord-015935-r2wd1yfa	303	2	induce	induce	VBP
cord-015935-r2wd1yfa	303	3	presynaptic	presynaptic	JJ
cord-015935-r2wd1yfa	303	4	differentiation	differentiation	NN
cord-015935-r2wd1yfa	303	5	in	in	IN
cord-015935-r2wd1yfa	303	6	glutamate	glutamate	NN
cord-015935-r2wd1yfa	303	7	axons	axon	NNS
cord-015935-r2wd1yfa	303	8	.	.	.
cord-015935-r2wd1yfa	304	1	SHANK3	SHANK3	NNP
cord-015935-r2wd1yfa	304	2	encodes	encode	VBZ
cord-015935-r2wd1yfa	304	3	for	for	IN
cord-015935-r2wd1yfa	304	4	a	a	DT
cord-015935-r2wd1yfa	304	5	postsynaptic	postsynaptic	JJ
cord-015935-r2wd1yfa	304	6	scaffolding	scaffolding	NN
cord-015935-r2wd1yfa	304	7	protein	protein	NN
cord-015935-r2wd1yfa	304	8	which	which	WDT
cord-015935-r2wd1yfa	304	9	regulates	regulate	VBZ
cord-015935-r2wd1yfa	304	10	the	the	DT
cord-015935-r2wd1yfa	304	11	structural	structural	JJ
cord-015935-r2wd1yfa	304	12	organization	organization	NN
cord-015935-r2wd1yfa	304	13	of	of	IN
cord-015935-r2wd1yfa	304	14	dendritic	dendritic	JJ
cord-015935-r2wd1yfa	304	15	spines	spine	NNS
cord-015935-r2wd1yfa	304	16	in	in	IN
cord-015935-r2wd1yfa	304	17	neurons	neuron	NNS
cord-015935-r2wd1yfa	304	18	.	.	.
cord-015935-r2wd1yfa	305	1	Consequently	consequently	RB
cord-015935-r2wd1yfa	305	2	,	,	,
cord-015935-r2wd1yfa	305	3	SHANK3	SHANK3	NNP
cord-015935-r2wd1yfa	305	4	is	be	VBZ
cord-015935-r2wd1yfa	305	5	a	a	DT
cord-015935-r2wd1yfa	305	6	binding	bind	VBG
cord-015935-r2wd1yfa	305	7	partner	partner	NN
cord-015935-r2wd1yfa	305	8	of	of	IN
cord-015935-r2wd1yfa	305	9	neuroligins	neuroligin	NNS
cord-015935-r2wd1yfa	305	10	.	.	.
cord-015935-r2wd1yfa	306	1	Neurexin	Neurexin	NNP
cord-015935-r2wd1yfa	306	2	induces	induce	VBZ
cord-015935-r2wd1yfa	306	3	glutamate	glutamate	NN
cord-015935-r2wd1yfa	306	4	postsynaptic	postsynaptic	JJ
cord-015935-r2wd1yfa	306	5	differentiation	differentiation	NN
cord-015935-r2wd1yfa	306	6	in	in	IN
cord-015935-r2wd1yfa	306	7	contacting	contact	VBG
cord-015935-r2wd1yfa	306	8	dendrites	dendrite	NNS
cord-015935-r2wd1yfa	306	9	.	.	.
cord-015935-r2wd1yfa	307	1	Altogether	altogether	RB
cord-015935-r2wd1yfa	307	2	,	,	,
cord-015935-r2wd1yfa	307	3	these	these	DT
cord-015935-r2wd1yfa	307	4	genes	gene	NNS
cord-015935-r2wd1yfa	307	5	appear	appear	VBP
cord-015935-r2wd1yfa	307	6	to	to	TO
cord-015935-r2wd1yfa	307	7	contribute	contribute	VB
cord-015935-r2wd1yfa	307	8	to	to	IN
cord-015935-r2wd1yfa	307	9	glutamatergic	glutamatergic	JJ
cord-015935-r2wd1yfa	307	10	synapse	synapse	NN
cord-015935-r2wd1yfa	307	11	formation	formation	NN
cord-015935-r2wd1yfa	307	12	.	.	.
cord-015935-r2wd1yfa	308	1	Neuronal	neuronal	JJ
cord-015935-r2wd1yfa	308	2	cell	cell	NN
cord-015935-r2wd1yfa	308	3	adhesion	adhesion	NN
cord-015935-r2wd1yfa	308	4	is	be	VBZ
cord-015935-r2wd1yfa	308	5	important	important	JJ
cord-015935-r2wd1yfa	308	6	in	in	IN
cord-015935-r2wd1yfa	308	7	the	the	DT
cord-015935-r2wd1yfa	308	8	development	development	NN
cord-015935-r2wd1yfa	308	9	of	of	IN
cord-015935-r2wd1yfa	308	10	the	the	DT
cord-015935-r2wd1yfa	308	11	nervous	nervous	JJ
cord-015935-r2wd1yfa	308	12	system	system	NN
cord-015935-r2wd1yfa	308	13	,	,	,
cord-015935-r2wd1yfa	308	14	contributing	contribute	VBG
cord-015935-r2wd1yfa	308	15	to	to	IN
cord-015935-r2wd1yfa	308	16	axonal	axonal	JJ
cord-015935-r2wd1yfa	308	17	guidance	guidance	NN
cord-015935-r2wd1yfa	308	18	,	,	,
cord-015935-r2wd1yfa	308	19	synaptic	synaptic	JJ
cord-015935-r2wd1yfa	308	20	formation	formation	NN
cord-015935-r2wd1yfa	308	21	and	and	CC
cord-015935-r2wd1yfa	308	22	plasticity	plasticity	NN
cord-015935-r2wd1yfa	308	23	,	,	,
cord-015935-r2wd1yfa	308	24	and	and	CC
cord-015935-r2wd1yfa	308	25	neuronalglial	neuronalglial	JJ
cord-015935-r2wd1yfa	308	26	interactions	interaction	NNS
cord-015935-r2wd1yfa	308	27	(	(	-LRB-
cord-015935-r2wd1yfa	308	28	Glessner	Glessner	NNP
cord-015935-r2wd1yfa	308	29	et	et	NNP
cord-015935-r2wd1yfa	308	30	al	al	NNP
cord-015935-r2wd1yfa	308	31	.	.	NNP
cord-015935-r2wd1yfa	308	32	,	,	,
cord-015935-r2wd1yfa	308	33	2009	2009	CD
cord-015935-r2wd1yfa	308	34	;	;	:
cord-015935-r2wd1yfa	308	35	Lien	Lien	NNP
cord-015935-r2wd1yfa	308	36	,	,	,
cord-015935-r2wd1yfa	308	37	Klezovitch	Klezovitch	NNP
cord-015935-r2wd1yfa	308	38	,	,	,
cord-015935-r2wd1yfa	308	39	&	&	CC
cord-015935-r2wd1yfa	308	40	Vasioukhin	Vasioukhin	NNP
cord-015935-r2wd1yfa	308	41	,	,	,
cord-015935-r2wd1yfa	308	42	2006	2006	CD
cord-015935-r2wd1yfa	308	43	)	)	-RRB-
cord-015935-r2wd1yfa	308	44	.	.	.
cord-015935-r2wd1yfa	309	1	Derangement	derangement	NN
cord-015935-r2wd1yfa	309	2	in	in	IN
cord-015935-r2wd1yfa	309	3	cell	cell	NN
cord-015935-r2wd1yfa	309	4	adhesion	adhesion	NN
cord-015935-r2wd1yfa	309	5	could	could	MD
cord-015935-r2wd1yfa	309	6	contribute	contribute	VB
cord-015935-r2wd1yfa	309	7	to	to	IN
cord-015935-r2wd1yfa	309	8	migrational	migrational	JJ
cord-015935-r2wd1yfa	309	9	abnormalities	abnormality	NNS
cord-015935-r2wd1yfa	309	10	including	include	VBG
cord-015935-r2wd1yfa	309	11	brain	brain	NN
cord-015935-r2wd1yfa	309	12	overgrowth	overgrowth	NN
cord-015935-r2wd1yfa	309	13	.	.	.
cord-015935-r2wd1yfa	310	1	Neuroligins	neuroligin	NNS
cord-015935-r2wd1yfa	310	2	are	be	VBP
cord-015935-r2wd1yfa	310	3	cell	cell	NN
cord-015935-r2wd1yfa	310	4	-	-	HYPH
cord-015935-r2wd1yfa	310	5	adhesion	adhesion	NN
cord-015935-r2wd1yfa	310	6	molecules	molecule	NNS
cord-015935-r2wd1yfa	310	7	localized	localize	VBN
cord-015935-r2wd1yfa	310	8	postsynaptically	postsynaptically	RB
cord-015935-r2wd1yfa	310	9	at	at	IN
cord-015935-r2wd1yfa	310	10	both	both	CC
cord-015935-r2wd1yfa	310	11	glutamatergic	glutamatergic	JJ
cord-015935-r2wd1yfa	311	1	(	(	-LRB-
cord-015935-r2wd1yfa	311	2	NLGN1	NLGN1	NNP
cord-015935-r2wd1yfa	311	3	,	,	,
cord-015935-r2wd1yfa	311	4	NLGN3	NLGN3	NNP
cord-015935-r2wd1yfa	311	5	,	,	,
cord-015935-r2wd1yfa	311	6	NLGN4	NLGN4	NNP
cord-015935-r2wd1yfa	311	7	,	,	,
cord-015935-r2wd1yfa	311	8	NLGN4Y	NLGN4Y	NNP
cord-015935-r2wd1yfa	311	9	)	)	-RRB-
cord-015935-r2wd1yfa	311	10	and	and	CC
cord-015935-r2wd1yfa	311	11	γ	γ	NN
cord-015935-r2wd1yfa	311	12	-	-	HYPH
cord-015935-r2wd1yfa	311	13	aminobutyric	aminobutyric	NNP
cord-015935-r2wd1yfa	312	1	acidergic	acidergic	NNP
cord-015935-r2wd1yfa	312	2	(	(	-LRB-
cord-015935-r2wd1yfa	312	3	NLGN2	nlgn2	NN
cord-015935-r2wd1yfa	312	4	)	)	-RRB-
cord-015935-r2wd1yfa	312	5	synapses	synapsis	NNS
cord-015935-r2wd1yfa	312	6	(	(	-LRB-
cord-015935-r2wd1yfa	312	7	Lintas	Lintas	NNP
cord-015935-r2wd1yfa	312	8	&	&	CC
cord-015935-r2wd1yfa	312	9	Persico	Persico	NNP
cord-015935-r2wd1yfa	312	10	,	,	,
cord-015935-r2wd1yfa	312	11	2009	2009	CD
cord-015935-r2wd1yfa	312	12	)	)	-RRB-
cord-015935-r2wd1yfa	312	13	.	.	.
cord-015935-r2wd1yfa	313	1	Neuroligins	neuroligin	NNS
cord-015935-r2wd1yfa	313	2	trigger	trigger	VBP
cord-015935-r2wd1yfa	313	3	the	the	DT
cord-015935-r2wd1yfa	313	4	formation	formation	NN
cord-015935-r2wd1yfa	313	5	of	of	IN
cord-015935-r2wd1yfa	313	6	functional	functional	JJ
cord-015935-r2wd1yfa	313	7	presynaptic	presynaptic	JJ
cord-015935-r2wd1yfa	313	8	structures	structure	NNS
cord-015935-r2wd1yfa	313	9	in	in	IN
cord-015935-r2wd1yfa	313	10	contacting	contact	VBG
cord-015935-r2wd1yfa	313	11	axons	axon	NNS
cord-015935-r2wd1yfa	313	12	.	.	.
cord-015935-r2wd1yfa	314	1	As	as	IN
cord-015935-r2wd1yfa	314	2	mentioned	mention	VBN
cord-015935-r2wd1yfa	314	3	above	above	RB
cord-015935-r2wd1yfa	314	4	,	,	,
cord-015935-r2wd1yfa	314	5	they	-PRON-	PRP
cord-015935-r2wd1yfa	314	6	interact	interact	VBP
cord-015935-r2wd1yfa	314	7	with	with	IN
cord-015935-r2wd1yfa	314	8	postsynaptic	postsynaptic	JJ
cord-015935-r2wd1yfa	314	9	scaffolding	scaffolding	NN
cord-015935-r2wd1yfa	314	10	proteins	protein	NNS
cord-015935-r2wd1yfa	314	11	such	such	JJ
cord-015935-r2wd1yfa	314	12	as	as	IN
cord-015935-r2wd1yfa	314	13	SHANK3	SHANK3	NNP
cord-015935-r2wd1yfa	314	14	(	(	-LRB-
cord-015935-r2wd1yfa	314	15	see	see	VB
cord-015935-r2wd1yfa	314	16	below	below	RB
cord-015935-r2wd1yfa	314	17	)	)	-RRB-
cord-015935-r2wd1yfa	314	18	.	.	.
cord-015935-r2wd1yfa	315	1	The	the	DT
cord-015935-r2wd1yfa	315	2	NLGN3	nlgn3	NN
cord-015935-r2wd1yfa	315	3	and	and	CC
cord-015935-r2wd1yfa	315	4	NLGN4	nlgn4	NN
cord-015935-r2wd1yfa	315	5	genes	gene	NNS
cord-015935-r2wd1yfa	315	6	are	be	VBP
cord-015935-r2wd1yfa	315	7	located	locate	VBN
cord-015935-r2wd1yfa	315	8	at	at	IN
cord-015935-r2wd1yfa	315	9	chromosomes	chromosome	NNS
cord-015935-r2wd1yfa	315	10	Xq13	Xq13	.
cord-015935-r2wd1yfa	315	11	and	and	CC
cord-015935-r2wd1yfa	315	12	Xq22	Xq22	NNP
cord-015935-r2wd1yfa	315	13	,	,	,
cord-015935-r2wd1yfa	315	14	33	33	CD
cord-015935-r2wd1yfa	315	15	,	,	,
cord-015935-r2wd1yfa	315	16	respectively	respectively	RB
cord-015935-r2wd1yfa	315	17	,	,	,
cord-015935-r2wd1yfa	315	18	and	and	CC
cord-015935-r2wd1yfa	315	19	mutations	mutation	NNS
cord-015935-r2wd1yfa	315	20	here	here	RB
cord-015935-r2wd1yfa	315	21	have	have	VBP
cord-015935-r2wd1yfa	315	22	been	be	VBN
cord-015935-r2wd1yfa	315	23	associated	associate	VBN
cord-015935-r2wd1yfa	315	24	with	with	IN
cord-015935-r2wd1yfa	315	25	autism	autism	NN
cord-015935-r2wd1yfa	315	26	Jamain	Jamain	NNP
cord-015935-r2wd1yfa	315	27	et	et	NNP
cord-015935-r2wd1yfa	315	28	al	al	NNP
cord-015935-r2wd1yfa	315	29	.	.	.
cord-015935-r2wd1yfa	316	1	(	(	-LRB-
cord-015935-r2wd1yfa	316	2	2003	2003	CD
cord-015935-r2wd1yfa	316	3	)	)	-RRB-
cord-015935-r2wd1yfa	316	4	.	.	.
cord-015935-r2wd1yfa	317	1	Extensive	extensive	JJ
cord-015935-r2wd1yfa	317	2	genetic	genetic	JJ
cord-015935-r2wd1yfa	317	3	screens	screen	NNS
cord-015935-r2wd1yfa	317	4	conducted	conduct	VBN
cord-015935-r2wd1yfa	317	5	by	by	IN
cord-015935-r2wd1yfa	317	6	several	several	JJ
cord-015935-r2wd1yfa	317	7	research	research	NN
cord-015935-r2wd1yfa	317	8	groups	group	NNS
cord-015935-r2wd1yfa	317	9	have	have	VBP
cord-015935-r2wd1yfa	317	10	confirmed	confirm	VBN
cord-015935-r2wd1yfa	317	11	the	the	DT
cord-015935-r2wd1yfa	317	12	low	low	JJ
cord-015935-r2wd1yfa	317	13	frequency	frequency	NN
cord-015935-r2wd1yfa	317	14	of	of	IN
cord-015935-r2wd1yfa	317	15	neuroligin	neuroligin	NNP
cord-015935-r2wd1yfa	317	16	mutations	mutation	NNS
cord-015935-r2wd1yfa	317	17	among	among	IN
cord-015935-r2wd1yfa	317	18	individuals	individual	NNS
cord-015935-r2wd1yfa	317	19	with	with	IN
cord-015935-r2wd1yfa	317	20	autism	autism	NN
cord-015935-r2wd1yfa	317	21	(	(	-LRB-
cord-015935-r2wd1yfa	317	22	Lintas	Lintas	NNP
cord-015935-r2wd1yfa	317	23	&	&	CC
cord-015935-r2wd1yfa	317	24	Persico	Persico	NNP
cord-015935-r2wd1yfa	317	25	,	,	,
cord-015935-r2wd1yfa	317	26	2009	2009	CD
cord-015935-r2wd1yfa	317	27	)	)	-RRB-
cord-015935-r2wd1yfa	317	28	.	.	.
cord-015935-r2wd1yfa	318	1	For	for	IN
cord-015935-r2wd1yfa	318	2	example	example	NN
cord-015935-r2wd1yfa	318	3	,	,	,
cord-015935-r2wd1yfa	318	4	Jamain	Jamain	NNP
cord-015935-r2wd1yfa	318	5	et	et	NNP
cord-015935-r2wd1yfa	318	6	al	al	NNP
cord-015935-r2wd1yfa	318	7	.	.	.
cord-015935-r2wd1yfa	319	1	(	(	-LRB-
cord-015935-r2wd1yfa	319	2	2003	2003	CD
cord-015935-r2wd1yfa	319	3	)	)	-RRB-
cord-015935-r2wd1yfa	319	4	found	find	VBD
cord-015935-r2wd1yfa	319	5	a	a	DT
cord-015935-r2wd1yfa	319	6	frameshift	frameshift	NN
cord-015935-r2wd1yfa	319	7	mutation	mutation	NN
cord-015935-r2wd1yfa	319	8	in	in	IN
cord-015935-r2wd1yfa	319	9	NLGN4	nlgn4	NN
cord-015935-r2wd1yfa	319	10	and	and	CC
cord-015935-r2wd1yfa	319	11	a	a	DT
cord-015935-r2wd1yfa	319	12	missense	missense	JJ
cord-015935-r2wd1yfa	319	13	mutation	mutation	NN
cord-015935-r2wd1yfa	319	14	in	in	IN
cord-015935-r2wd1yfa	319	15	NLGN3	NLGN3	NNP
cord-015935-r2wd1yfa	319	16	in	in	IN
cord-015935-r2wd1yfa	319	17	two	two	CD
cord-015935-r2wd1yfa	319	18	unrelated	unrelated	JJ
cord-015935-r2wd1yfa	319	19	Swedish	swedish	JJ
cord-015935-r2wd1yfa	319	20	families	family	NNS
cord-015935-r2wd1yfa	319	21	,	,	,
cord-015935-r2wd1yfa	319	22	inherited	inherit	VBN
cord-015935-r2wd1yfa	319	23	from	from	IN
cord-015935-r2wd1yfa	319	24	unaffected	unaffected	JJ
cord-015935-r2wd1yfa	319	25	mothers	mother	NNS
cord-015935-r2wd1yfa	319	26	.	.	.
cord-015935-r2wd1yfa	320	1	Laumonnier	Laumonnier	NNP
cord-015935-r2wd1yfa	320	2	et	et	NNP
cord-015935-r2wd1yfa	320	3	al	al	NNP
cord-015935-r2wd1yfa	320	4	.	.	.
cord-015935-r2wd1yfa	321	1	(	(	-LRB-
cord-015935-r2wd1yfa	321	2	2004	2004	CD
cord-015935-r2wd1yfa	321	3	)	)	-RRB-
cord-015935-r2wd1yfa	321	4	reported	report	VBD
cord-015935-r2wd1yfa	321	5	a	a	DT
cord-015935-r2wd1yfa	321	6	frameshift	frameshift	NN
cord-015935-r2wd1yfa	321	7	mutation	mutation	NN
cord-015935-r2wd1yfa	321	8	in	in	IN
cord-015935-r2wd1yfa	321	9	NLGN4	nlgn4	NN
cord-015935-r2wd1yfa	321	10	in	in	IN
cord-015935-r2wd1yfa	321	11	13	13	CD
cord-015935-r2wd1yfa	321	12	affected	affected	JJ
cord-015935-r2wd1yfa	321	13	male	male	JJ
cord-015935-r2wd1yfa	321	14	members	member	NNS
cord-015935-r2wd1yfa	321	15	of	of	IN
cord-015935-r2wd1yfa	321	16	a	a	DT
cord-015935-r2wd1yfa	321	17	single	single	JJ
cord-015935-r2wd1yfa	321	18	pedigree	pedigree	NN
cord-015935-r2wd1yfa	321	19	.	.	.
cord-015935-r2wd1yfa	322	1	Lawson	Lawson	NNP
cord-015935-r2wd1yfa	322	2	-	-	HYPH
cord-015935-r2wd1yfa	322	3	Yuen	Yuen	NNP
cord-015935-r2wd1yfa	322	4	,	,	,
cord-015935-r2wd1yfa	322	5	Saldivar	Saldivar	NNP
cord-015935-r2wd1yfa	322	6	,	,	,
cord-015935-r2wd1yfa	322	7	Sommer	Sommer	NNP
cord-015935-r2wd1yfa	322	8	,	,	,
cord-015935-r2wd1yfa	322	9	and	and	CC
cord-015935-r2wd1yfa	322	10	Picker	Picker	NNP
cord-015935-r2wd1yfa	322	11	(	(	-LRB-
cord-015935-r2wd1yfa	322	12	2008	2008	CD
cord-015935-r2wd1yfa	322	13	)	)	-RRB-
cord-015935-r2wd1yfa	322	14	found	find	VBD
cord-015935-r2wd1yfa	322	15	a	a	DT
cord-015935-r2wd1yfa	322	16	deletion	deletion	NN
cord-015935-r2wd1yfa	322	17	of	of	IN
cord-015935-r2wd1yfa	322	18	exons	exon	NNS
cord-015935-r2wd1yfa	322	19	4	4	CD
cord-015935-r2wd1yfa	322	20	-	-	SYM
cord-015935-r2wd1yfa	322	21	6	6	CD
cord-015935-r2wd1yfa	322	22	of	of	IN
cord-015935-r2wd1yfa	322	23	NLGN4	nlgn4	NN
cord-015935-r2wd1yfa	322	24	in	in	IN
cord-015935-r2wd1yfa	322	25	a	a	DT
cord-015935-r2wd1yfa	322	26	boy	boy	NN
cord-015935-r2wd1yfa	322	27	with	with	IN
cord-015935-r2wd1yfa	322	28	autism	autism	NN
cord-015935-r2wd1yfa	322	29	and	and	CC
cord-015935-r2wd1yfa	322	30	in	in	IN
cord-015935-r2wd1yfa	322	31	his	-PRON-	PRP$
cord-015935-r2wd1yfa	322	32	brother	brother	NN
cord-015935-r2wd1yfa	322	33	with	with	IN
cord-015935-r2wd1yfa	322	34	Tourette	Tourette	NNP
cord-015935-r2wd1yfa	322	35	syndrome	syndrome	NN
cord-015935-r2wd1yfa	322	36	whose	whose	WP$
cord-015935-r2wd1yfa	322	37	mother	mother	NN
cord-015935-r2wd1yfa	322	38	showed	show	VBD
cord-015935-r2wd1yfa	322	39	psychiatric	psychiatric	JJ
cord-015935-r2wd1yfa	322	40	problems	problem	NNS
cord-015935-r2wd1yfa	322	41	and	and	CC
cord-015935-r2wd1yfa	322	42	also	also	RB
cord-015935-r2wd1yfa	322	43	carried	carry	VBD
cord-015935-r2wd1yfa	322	44	the	the	DT
cord-015935-r2wd1yfa	322	45	mutation	mutation	NN
cord-015935-r2wd1yfa	322	46	.	.	.
cord-015935-r2wd1yfa	323	1	Neuroligin	Neuroligin	NNP
cord-015935-r2wd1yfa	323	2	mutation	mutation	NN
cord-015935-r2wd1yfa	323	3	carriers	carrier	NNS
cord-015935-r2wd1yfa	323	4	,	,	,
cord-015935-r2wd1yfa	323	5	however	however	RB
cord-015935-r2wd1yfa	323	6	,	,	,
cord-015935-r2wd1yfa	323	7	display	display	VB
cord-015935-r2wd1yfa	323	8	a	a	DT
cord-015935-r2wd1yfa	323	9	variety	variety	NN
cord-015935-r2wd1yfa	323	10	of	of	IN
cord-015935-r2wd1yfa	323	11	syndromes	syndrome	NNS
cord-015935-r2wd1yfa	323	12	,	,	,
cord-015935-r2wd1yfa	323	13	such	such	JJ
cord-015935-r2wd1yfa	323	14	as	as	IN
cord-015935-r2wd1yfa	323	15	X	X	NNS
cord-015935-r2wd1yfa	323	16	-	-	HYPH
cord-015935-r2wd1yfa	323	17	linked	link	VBN
cord-015935-r2wd1yfa	323	18	mental	mental	JJ
cord-015935-r2wd1yfa	323	19	retardation	retardation	NN
cord-015935-r2wd1yfa	323	20	without	without	IN
cord-015935-r2wd1yfa	323	21	autism	autism	NN
cord-015935-r2wd1yfa	324	1	(	(	-LRB-
cord-015935-r2wd1yfa	324	2	Laumonnier	Laumonnier	NNP
cord-015935-r2wd1yfa	324	3	et	et	NNP
cord-015935-r2wd1yfa	324	4	al	al	NNP
cord-015935-r2wd1yfa	324	5	.	.	NNP
cord-015935-r2wd1yfa	324	6	,	,	,
cord-015935-r2wd1yfa	324	7	2004	2004	CD
cord-015935-r2wd1yfa	324	8	)	)	-RRB-
cord-015935-r2wd1yfa	324	9	,	,	,
cord-015935-r2wd1yfa	324	10	Asperger	Asperger	NNP
cord-015935-r2wd1yfa	324	11	's	's	POS
cord-015935-r2wd1yfa	324	12	syndrome	syndrome	NN
cord-015935-r2wd1yfa	324	13	,	,	,
cord-015935-r2wd1yfa	324	14	autistic	autistic	JJ
cord-015935-r2wd1yfa	324	15	disorder	disorder	NN
cord-015935-r2wd1yfa	324	16	of	of	IN
cord-015935-r2wd1yfa	324	17	variable	variable	JJ
cord-015935-r2wd1yfa	324	18	severity	severity	NN
cord-015935-r2wd1yfa	324	19	,	,	,
cord-015935-r2wd1yfa	324	20	and	and	CC
cord-015935-r2wd1yfa	324	21	PDD	PDD	NNP
cord-015935-r2wd1yfa	324	22	-	-	HYPH
cord-015935-r2wd1yfa	324	23	NOS	NOS	NNP
cord-015935-r2wd1yfa	324	24	(	(	-LRB-
cord-015935-r2wd1yfa	324	25	Yan	Yan	NNP
cord-015935-r2wd1yfa	324	26	et	et	NNP
cord-015935-r2wd1yfa	324	27	al	al	NNP
cord-015935-r2wd1yfa	324	28	.	.	NNP
cord-015935-r2wd1yfa	324	29	,	,	,
cord-015935-r2wd1yfa	324	30	2005	2005	CD
cord-015935-r2wd1yfa	324	31	)	)	-RRB-
cord-015935-r2wd1yfa	324	32	.	.	.
cord-015935-r2wd1yfa	325	1	The	the	DT
cord-015935-r2wd1yfa	325	2	symptoms	symptom	NNS
cord-015935-r2wd1yfa	325	3	may	may	MD
cord-015935-r2wd1yfa	325	4	be	be	VB
cord-015935-r2wd1yfa	325	5	slow	slow	JJ
cord-015935-r2wd1yfa	325	6	,	,	,
cord-015935-r2wd1yfa	325	7	or	or	CC
cord-015935-r2wd1yfa	325	8	abrupt	abrupt	JJ
cord-015935-r2wd1yfa	325	9	and	and	CC
cord-015935-r2wd1yfa	325	10	associated	associate	VBN
cord-015935-r2wd1yfa	325	11	with	with	IN
cord-015935-r2wd1yfa	325	12	regression	regression	NN
cord-015935-r2wd1yfa	325	13	.	.	.
cord-015935-r2wd1yfa	326	1	Despite	despite	IN
cord-015935-r2wd1yfa	326	2	intensive	intensive	JJ
cord-015935-r2wd1yfa	326	3	investigation	investigation	NN
cord-015935-r2wd1yfa	326	4	,	,	,
cord-015935-r2wd1yfa	326	5	the	the	DT
cord-015935-r2wd1yfa	326	6	low	low	JJ
cord-015935-r2wd1yfa	326	7	frequency	frequency	NN
cord-015935-r2wd1yfa	326	8	of	of	IN
cord-015935-r2wd1yfa	326	9	neuroligin	neuroligin	NNP
cord-015935-r2wd1yfa	326	10	mutations	mutation	NNS
cord-015935-r2wd1yfa	326	11	and	and	CC
cord-015935-r2wd1yfa	326	12	the	the	DT
cord-015935-r2wd1yfa	326	13	lack	lack	NN
cord-015935-r2wd1yfa	326	14	of	of	IN
cord-015935-r2wd1yfa	326	15	similar	similar	JJ
cord-015935-r2wd1yfa	326	16	phenotypes	phenotype	NNS
cord-015935-r2wd1yfa	326	17	have	have	VBP
cord-015935-r2wd1yfa	326	18	led	lead	VBN
cord-015935-r2wd1yfa	326	19	to	to	IN
cord-015935-r2wd1yfa	326	20	the	the	DT
cord-015935-r2wd1yfa	326	21	recommendation	recommendation	NN
cord-015935-r2wd1yfa	326	22	that	that	IN
cord-015935-r2wd1yfa	326	23	neuroligins	neuroligins	NNP
cord-015935-r2wd1yfa	326	24	should	should	MD
cord-015935-r2wd1yfa	326	25	not	not	RB
cord-015935-r2wd1yfa	326	26	be	be	VB
cord-015935-r2wd1yfa	326	27	included	include	VBN
cord-015935-r2wd1yfa	326	28	in	in	IN
cord-015935-r2wd1yfa	326	29	widespread	widespread	JJ
cord-015935-r2wd1yfa	326	30	screens	screen	NNS
cord-015935-r2wd1yfa	326	31	for	for	IN
cord-015935-r2wd1yfa	326	32	individuals	individual	NNS
cord-015935-r2wd1yfa	326	33	with	with	IN
cord-015935-r2wd1yfa	326	34	nonsyndromic	nonsyndromic	NNP
cord-015935-r2wd1yfa	326	35	autism	autism	NNP
cord-015935-r2wd1yfa	326	36	(	(	-LRB-
cord-015935-r2wd1yfa	326	37	Lintas	Lintas	NNP
cord-015935-r2wd1yfa	326	38	&	&	CC
cord-015935-r2wd1yfa	326	39	Persico	Persico	NNP
cord-015935-r2wd1yfa	326	40	,	,	,
cord-015935-r2wd1yfa	326	41	2009	2009	CD
cord-015935-r2wd1yfa	326	42	)	)	-RRB-
cord-015935-r2wd1yfa	326	43	.	.	.
cord-015935-r2wd1yfa	327	1	The	the	DT
cord-015935-r2wd1yfa	327	2	SHANK3	shank3	NN
cord-015935-r2wd1yfa	327	3	gene	gene	NN
cord-015935-r2wd1yfa	327	4	is	be	VBZ
cord-015935-r2wd1yfa	327	5	located	locate	VBN
cord-015935-r2wd1yfa	327	6	on	on	IN
cord-015935-r2wd1yfa	327	7	chromosome	chromosome	NN
cord-015935-r2wd1yfa	327	8	22q13.3	22q13.3	CD
cord-015935-r2wd1yfa	327	9	which	which	WDT
cord-015935-r2wd1yfa	327	10	encodes	encode	VBZ
cord-015935-r2wd1yfa	327	11	for	for	IN
cord-015935-r2wd1yfa	327	12	a	a	DT
cord-015935-r2wd1yfa	327	13	scaffolding	scaffold	VBG
cord-015935-r2wd1yfa	327	14	protein	protein	NN
cord-015935-r2wd1yfa	327	15	found	find	VBN
cord-015935-r2wd1yfa	327	16	in	in	IN
cord-015935-r2wd1yfa	327	17	the	the	DT
cord-015935-r2wd1yfa	327	18	postsynaptic	postsynaptic	JJ
cord-015935-r2wd1yfa	327	19	density	density	NN
cord-015935-r2wd1yfa	327	20	complex	complex	NN
cord-015935-r2wd1yfa	327	21	of	of	IN
cord-015935-r2wd1yfa	327	22	excitatory	excitatory	JJ
cord-015935-r2wd1yfa	327	23	synapses	synapsis	NNS
cord-015935-r2wd1yfa	327	24	binding	bind	VBG
cord-015935-r2wd1yfa	327	25	to	to	IN
cord-015935-r2wd1yfa	327	26	neuroligins	neuroligin	NNS
cord-015935-r2wd1yfa	327	27	.	.	.
cord-015935-r2wd1yfa	328	1	Recently	recently	RB
cord-015935-r2wd1yfa	328	2	,	,	,
cord-015935-r2wd1yfa	328	3	two	two	CD
cord-015935-r2wd1yfa	328	4	studies	study	NNS
cord-015935-r2wd1yfa	328	5	have	have	VBP
cord-015935-r2wd1yfa	328	6	reported	report	VBN
cord-015935-r2wd1yfa	328	7	a	a	DT
cord-015935-r2wd1yfa	328	8	correlation	correlation	NN
cord-015935-r2wd1yfa	328	9	between	between	IN
cord-015935-r2wd1yfa	328	10	mutations	mutation	NNS
cord-015935-r2wd1yfa	328	11	affecting	affect	VBG
cord-015935-r2wd1yfa	328	12	SHANK3	shank3	NN
cord-015935-r2wd1yfa	328	13	and	and	CC
cord-015935-r2wd1yfa	328	14	an	an	DT
cord-015935-r2wd1yfa	328	15	autism	autism	NN
cord-015935-r2wd1yfa	328	16	phenotype	phenotype	NN
cord-015935-r2wd1yfa	328	17	characterized	characterize	VBN
cord-015935-r2wd1yfa	328	18	by	by	IN
cord-015935-r2wd1yfa	328	19	severe	severe	JJ
cord-015935-r2wd1yfa	328	20	verbal	verbal	JJ
cord-015935-r2wd1yfa	328	21	and	and	CC
cord-015935-r2wd1yfa	328	22	social	social	JJ
cord-015935-r2wd1yfa	328	23	deficits	deficit	NNS
cord-015935-r2wd1yfa	328	24	(	(	-LRB-
cord-015935-r2wd1yfa	328	25	Durand	Durand	NNP
cord-015935-r2wd1yfa	328	26	et	et	NNP
cord-015935-r2wd1yfa	328	27	al	al	NNP
cord-015935-r2wd1yfa	328	28	.	.	NNP
cord-015935-r2wd1yfa	328	29	,	,	,
cord-015935-r2wd1yfa	328	30	2007	2007	CD
cord-015935-r2wd1yfa	328	31	;	;	:
cord-015935-r2wd1yfa	328	32	Moessner	Moessner	NNP
cord-015935-r2wd1yfa	328	33	et	et	NNP
cord-015935-r2wd1yfa	328	34	al	al	NNP
cord-015935-r2wd1yfa	328	35	.	.	NNP
cord-015935-r2wd1yfa	328	36	,	,	,
cord-015935-r2wd1yfa	328	37	2007	2007	CD
cord-015935-r2wd1yfa	328	38	)	)	-RRB-
cord-015935-r2wd1yfa	328	39	.	.	.
cord-015935-r2wd1yfa	329	1	Of	of	IN
cord-015935-r2wd1yfa	329	2	the	the	DT
cord-015935-r2wd1yfa	329	3	seven	seven	CD
cord-015935-r2wd1yfa	329	4	patients	patient	NNS
cord-015935-r2wd1yfa	329	5	reported	report	VBN
cord-015935-r2wd1yfa	329	6	with	with	IN
cord-015935-r2wd1yfa	329	7	the	the	DT
cord-015935-r2wd1yfa	329	8	SHANK3	shank3	NN
cord-015935-r2wd1yfa	329	9	gene	gene	NN
cord-015935-r2wd1yfa	329	10	mutations	mutation	NNS
cord-015935-r2wd1yfa	329	11	,	,	,
cord-015935-r2wd1yfa	329	12	five	five	CD
cord-015935-r2wd1yfa	329	13	were	be	VBD
cord-015935-r2wd1yfa	329	14	deletions	deletion	NNS
cord-015935-r2wd1yfa	329	15	,	,	,
cord-015935-r2wd1yfa	329	16	one	one	CD
cord-015935-r2wd1yfa	329	17	was	be	VBD
cord-015935-r2wd1yfa	329	18	a	a	DT
cord-015935-r2wd1yfa	329	19	missense	missense	NN
cord-015935-r2wd1yfa	329	20	,	,	,
cord-015935-r2wd1yfa	329	21	and	and	CC
cord-015935-r2wd1yfa	329	22	another	another	DT
cord-015935-r2wd1yfa	329	23	a	a	DT
cord-015935-r2wd1yfa	329	24	frameshift	frameshift	NN
cord-015935-r2wd1yfa	329	25	mutation	mutation	NN
cord-015935-r2wd1yfa	329	26	.	.	.
cord-015935-r2wd1yfa	330	1	In	in	IN
cord-015935-r2wd1yfa	330	2	addition	addition	NN
cord-015935-r2wd1yfa	330	3	,	,	,
cord-015935-r2wd1yfa	330	4	rare	rare	JJ
cord-015935-r2wd1yfa	330	5	SHANK3	shank3	NN
cord-015935-r2wd1yfa	330	6	variations	variation	NNS
cord-015935-r2wd1yfa	330	7	were	be	VBD
cord-015935-r2wd1yfa	330	8	present	present	JJ
cord-015935-r2wd1yfa	330	9	in	in	IN
cord-015935-r2wd1yfa	330	10	the	the	DT
cord-015935-r2wd1yfa	330	11	autism	autism	NN
cord-015935-r2wd1yfa	330	12	group	group	NN
cord-015935-r2wd1yfa	330	13	,	,	,
cord-015935-r2wd1yfa	330	14	but	but	CC
cord-015935-r2wd1yfa	330	15	not	not	RB
cord-015935-r2wd1yfa	330	16	in	in	IN
cord-015935-r2wd1yfa	330	17	the	the	DT
cord-015935-r2wd1yfa	330	18	control	control	NN
cord-015935-r2wd1yfa	330	19	group	group	NN
cord-015935-r2wd1yfa	330	20	.	.	.
cord-015935-r2wd1yfa	331	1	These	these	DT
cord-015935-r2wd1yfa	331	2	variations	variation	NNS
cord-015935-r2wd1yfa	331	3	were	be	VBD
cord-015935-r2wd1yfa	331	4	inherited	inherit	VBN
cord-015935-r2wd1yfa	331	5	from	from	IN
cord-015935-r2wd1yfa	331	6	healthy	healthy	JJ
cord-015935-r2wd1yfa	331	7	parents	parent	NNS
cord-015935-r2wd1yfa	331	8	and	and	CC
cord-015935-r2wd1yfa	331	9	they	-PRON-	PRP
cord-015935-r2wd1yfa	331	10	were	be	VBD
cord-015935-r2wd1yfa	331	11	present	present	JJ
cord-015935-r2wd1yfa	331	12	in	in	IN
cord-015935-r2wd1yfa	331	13	unaffected	unaffected	JJ
cord-015935-r2wd1yfa	331	14	siblings	sibling	NNS
cord-015935-r2wd1yfa	331	15	,	,	,
cord-015935-r2wd1yfa	331	16	perhaps	perhaps	RB
cord-015935-r2wd1yfa	331	17	demonstrating	demonstrate	VBG
cord-015935-r2wd1yfa	331	18	incomplete	incomplete	JJ
cord-015935-r2wd1yfa	331	19	penetrance	penetrance	NN
cord-015935-r2wd1yfa	331	20	.	.	.
cord-015935-r2wd1yfa	332	1	Another	another	DT
cord-015935-r2wd1yfa	332	2	interesting	interesting	JJ
cord-015935-r2wd1yfa	332	3	observation	observation	NN
cord-015935-r2wd1yfa	332	4	is	be	VBZ
cord-015935-r2wd1yfa	332	5	that	that	IN
cord-015935-r2wd1yfa	332	6	in	in	IN
cord-015935-r2wd1yfa	332	7	both	both	DT
cord-015935-r2wd1yfa	332	8	studies	study	NNS
cord-015935-r2wd1yfa	332	9	(	(	-LRB-
cord-015935-r2wd1yfa	332	10	Durand	Durand	NNP
cord-015935-r2wd1yfa	332	11	et	et	NNP
cord-015935-r2wd1yfa	332	12	al	al	NNP
cord-015935-r2wd1yfa	332	13	.	.	NNP
cord-015935-r2wd1yfa	332	14	,	,	,
cord-015935-r2wd1yfa	332	15	2007	2007	CD
cord-015935-r2wd1yfa	332	16	;	;	:
cord-015935-r2wd1yfa	332	17	Moessner	Moessner	NNP
cord-015935-r2wd1yfa	332	18	et	et	NNP
cord-015935-r2wd1yfa	332	19	al	al	NNP
cord-015935-r2wd1yfa	332	20	.	.	NNP
cord-015935-r2wd1yfa	332	21	,	,	,
cord-015935-r2wd1yfa	332	22	2007	2007	CD
cord-015935-r2wd1yfa	332	23	)	)	-RRB-
cord-015935-r2wd1yfa	332	24	,	,	,
cord-015935-r2wd1yfa	332	25	the	the	DT
cord-015935-r2wd1yfa	332	26	SHANK3	shank3	NN
cord-015935-r2wd1yfa	332	27	deletion	deletion	NN
cord-015935-r2wd1yfa	332	28	was	be	VBD
cord-015935-r2wd1yfa	332	29	inherited	inherit	VBN
cord-015935-r2wd1yfa	332	30	via	via	IN
cord-015935-r2wd1yfa	332	31	a	a	DT
cord-015935-r2wd1yfa	332	32	paternal	paternal	JJ
cord-015935-r2wd1yfa	332	33	balanced	balanced	JJ
cord-015935-r2wd1yfa	332	34	translocation	translocation	NN
cord-015935-r2wd1yfa	332	35	.	.	.
cord-015935-r2wd1yfa	333	1	Further	further	RB
cord-015935-r2wd1yfa	333	2	,	,	,
cord-015935-r2wd1yfa	333	3	in	in	IN
cord-015935-r2wd1yfa	333	4	both	both	DT
cord-015935-r2wd1yfa	333	5	studies	study	NNS
cord-015935-r2wd1yfa	333	6	,	,	,
cord-015935-r2wd1yfa	333	7	siblings	sibling	NNS
cord-015935-r2wd1yfa	333	8	of	of	IN
cord-015935-r2wd1yfa	333	9	the	the	DT
cord-015935-r2wd1yfa	333	10	probands	proband	NNS
cord-015935-r2wd1yfa	333	11	with	with	IN
cord-015935-r2wd1yfa	333	12	SHANK3	SHANK3	NNP
cord-015935-r2wd1yfa	333	13	abnormalities	abnormality	NNS
cord-015935-r2wd1yfa	333	14	had	have	VBD
cord-015935-r2wd1yfa	333	15	partial	partial	JJ
cord-015935-r2wd1yfa	333	16	22q13	22q13	CD
cord-015935-r2wd1yfa	333	17	trisomy	trisomy	NN
cord-015935-r2wd1yfa	333	18	that	that	WDT
cord-015935-r2wd1yfa	333	19	resulted	result	VBD
cord-015935-r2wd1yfa	333	20	in	in	IN
cord-015935-r2wd1yfa	333	21	attention	attention	NN
cord-015935-r2wd1yfa	333	22	-	-	HYPH
cord-015935-r2wd1yfa	333	23	deficit	deficit	NN
cord-015935-r2wd1yfa	333	24	hyperactivity	hyperactivity	NN
cord-015935-r2wd1yfa	333	25	disorder	disorder	NN
cord-015935-r2wd1yfa	333	26	(	(	-LRB-
cord-015935-r2wd1yfa	333	27	Moessner	Moessner	NNP
cord-015935-r2wd1yfa	333	28	et	et	NNP
cord-015935-r2wd1yfa	333	29	al	al	NNP
cord-015935-r2wd1yfa	333	30	.	.	NNP
cord-015935-r2wd1yfa	333	31	,	,	,
cord-015935-r2wd1yfa	333	32	2007	2007	CD
cord-015935-r2wd1yfa	333	33	)	)	-RRB-
cord-015935-r2wd1yfa	333	34	and	and	CC
cord-015935-r2wd1yfa	333	35	Asperger	Asperger	NNP
cord-015935-r2wd1yfa	333	36	's	's	POS
cord-015935-r2wd1yfa	333	37	syndrome	syndrome	NN
cord-015935-r2wd1yfa	333	38	with	with	IN
cord-015935-r2wd1yfa	333	39	early	early	JJ
cord-015935-r2wd1yfa	333	40	language	language	NN
cord-015935-r2wd1yfa	333	41	development	development	NN
cord-015935-r2wd1yfa	333	42	(	(	-LRB-
cord-015935-r2wd1yfa	333	43	Durand	Durand	NNP
cord-015935-r2wd1yfa	333	44	et	et	NNP
cord-015935-r2wd1yfa	333	45	al	al	NNP
cord-015935-r2wd1yfa	333	46	.	.	NNP
cord-015935-r2wd1yfa	333	47	,	,	,
cord-015935-r2wd1yfa	333	48	2007	2007	CD
cord-015935-r2wd1yfa	333	49	)	)	-RRB-
cord-015935-r2wd1yfa	333	50	.	.	.
cord-015935-r2wd1yfa	334	1	Like	like	IN
cord-015935-r2wd1yfa	334	2	neuroligins	neuroligin	NNS
cord-015935-r2wd1yfa	334	3	,	,	,
cord-015935-r2wd1yfa	334	4	SHANK3	shank3	NN
cord-015935-r2wd1yfa	334	5	mutations	mutation	NNS
cord-015935-r2wd1yfa	334	6	are	be	VBP
cord-015935-r2wd1yfa	334	7	very	very	RB
cord-015935-r2wd1yfa	334	8	rare	rare	JJ
cord-015935-r2wd1yfa	334	9	.	.	.
cord-015935-r2wd1yfa	335	1	However	however	RB
cord-015935-r2wd1yfa	335	2	,	,	,
cord-015935-r2wd1yfa	335	3	because	because	IN
cord-015935-r2wd1yfa	335	4	of	of	IN
cord-015935-r2wd1yfa	335	5	the	the	DT
cord-015935-r2wd1yfa	335	6	robust	robust	JJ
cord-015935-r2wd1yfa	335	7	genotype	genotype	NN
cord-015935-r2wd1yfa	335	8	-	-	HYPH
cord-015935-r2wd1yfa	335	9	phenotype	phenotype	NN
cord-015935-r2wd1yfa	335	10	correlation	correlation	NN
cord-015935-r2wd1yfa	335	11	reported	report	VBN
cord-015935-r2wd1yfa	335	12	in	in	IN
cord-015935-r2wd1yfa	335	13	two	two	CD
cord-015935-r2wd1yfa	335	14	studies	study	NNS
cord-015935-r2wd1yfa	335	15	(	(	-LRB-
cord-015935-r2wd1yfa	335	16	Durand	Durand	NNP
cord-015935-r2wd1yfa	335	17	et	et	NNP
cord-015935-r2wd1yfa	335	18	al	al	NNP
cord-015935-r2wd1yfa	335	19	.	.	NNP
cord-015935-r2wd1yfa	335	20	,	,	,
cord-015935-r2wd1yfa	335	21	2007	2007	CD
cord-015935-r2wd1yfa	335	22	;	;	:
cord-015935-r2wd1yfa	335	23	Moessner	Moessner	NNP
cord-015935-r2wd1yfa	335	24	et	et	NNP
cord-015935-r2wd1yfa	335	25	al	al	NNP
cord-015935-r2wd1yfa	335	26	.	.	NNP
cord-015935-r2wd1yfa	335	27	,	,	,
cord-015935-r2wd1yfa	335	28	2007	2007	CD
cord-015935-r2wd1yfa	335	29	)	)	-RRB-
cord-015935-r2wd1yfa	335	30	,	,	,
cord-015935-r2wd1yfa	335	31	it	-PRON-	PRP
cord-015935-r2wd1yfa	335	32	has	have	VBZ
cord-015935-r2wd1yfa	335	33	been	be	VBN
cord-015935-r2wd1yfa	335	34	recommended	recommend	VBN
cord-015935-r2wd1yfa	335	35	that	that	IN
cord-015935-r2wd1yfa	335	36	children	child	NNS
cord-015935-r2wd1yfa	335	37	with	with	IN
cord-015935-r2wd1yfa	335	38	severe	severe	JJ
cord-015935-r2wd1yfa	335	39	language	language	NN
cord-015935-r2wd1yfa	335	40	and	and	CC
cord-015935-r2wd1yfa	335	41	social	social	JJ
cord-015935-r2wd1yfa	335	42	impairment	impairment	NN
cord-015935-r2wd1yfa	335	43	obtain	obtain	VBP
cord-015935-r2wd1yfa	335	44	SHANK3	shank3	JJ
cord-015935-r2wd1yfa	335	45	mutation	mutation	NN
cord-015935-r2wd1yfa	335	46	screening	screening	NN
cord-015935-r2wd1yfa	335	47	(	(	-LRB-
cord-015935-r2wd1yfa	335	48	Lintas	Lintas	NNP
cord-015935-r2wd1yfa	335	49	&	&	CC
cord-015935-r2wd1yfa	335	50	Persico	Persico	NNP
cord-015935-r2wd1yfa	335	51	,	,	,
cord-015935-r2wd1yfa	335	52	2009	2009	CD
cord-015935-r2wd1yfa	335	53	)	)	-RRB-
cord-015935-r2wd1yfa	335	54	.	.	.
cord-015935-r2wd1yfa	336	1	Presynaptic	presynaptic	JJ
cord-015935-r2wd1yfa	336	2	neurexins	neurexin	NNS
cord-015935-r2wd1yfa	336	3	influence	influence	VBP
cord-015935-r2wd1yfa	336	4	postsynaptic	postsynaptic	JJ
cord-015935-r2wd1yfa	336	5	differentiation	differentiation	NN
cord-015935-r2wd1yfa	336	6	in	in	IN
cord-015935-r2wd1yfa	336	7	contacting	contact	VBG
cord-015935-r2wd1yfa	336	8	dendrites	dendrite	NNS
cord-015935-r2wd1yfa	336	9	by	by	IN
cord-015935-r2wd1yfa	336	10	interactions	interaction	NNS
cord-015935-r2wd1yfa	336	11	with	with	IN
cord-015935-r2wd1yfa	336	12	postsynaptic	postsynaptic	JJ
cord-015935-r2wd1yfa	336	13	neuroligins	neuroligin	NNS
cord-015935-r2wd1yfa	336	14	.	.	.
cord-015935-r2wd1yfa	337	1	Three	three	CD
cord-015935-r2wd1yfa	337	2	neurexin	neurexin	NNP
cord-015935-r2wd1yfa	337	3	genes	gene	NNS
cord-015935-r2wd1yfa	337	4	(	(	-LRB-
cord-015935-r2wd1yfa	337	5	NRXN1	nrxn1	NN
cord-015935-r2wd1yfa	337	6	,	,	,
cord-015935-r2wd1yfa	337	7	NRXN2	nrxn2	NN
cord-015935-r2wd1yfa	337	8	,	,	,
cord-015935-r2wd1yfa	337	9	and	and	CC
cord-015935-r2wd1yfa	337	10	NRXN3	NRXN3	NNP
cord-015935-r2wd1yfa	337	11	)	)	-RRB-
cord-015935-r2wd1yfa	337	12	are	be	VBP
cord-015935-r2wd1yfa	337	13	located	locate	VBN
cord-015935-r2wd1yfa	337	14	on	on	IN
cord-015935-r2wd1yfa	337	15	chromosome	chromosome	NN
cord-015935-r2wd1yfa	337	16	loci	locus	NNS
cord-015935-r2wd1yfa	337	17	2q32	2q32	CD
cord-015935-r2wd1yfa	337	18	,	,	,
cord-015935-r2wd1yfa	337	19	11q13	11q13	CD
cord-015935-r2wd1yfa	337	20	,	,	,
cord-015935-r2wd1yfa	337	21	and	and	CC
cord-015935-r2wd1yfa	337	22	14q24.3-q31.1	14q24.3-q31.1	CD
cord-015935-r2wd1yfa	337	23	,	,	,
cord-015935-r2wd1yfa	337	24	respectively	respectively	RB
cord-015935-r2wd1yfa	337	25	.	.	.
cord-015935-r2wd1yfa	338	1	Again	again	RB
cord-015935-r2wd1yfa	338	2	,	,	,
cord-015935-r2wd1yfa	338	3	neurexin	neurexin	NNP
cord-015935-r2wd1yfa	338	4	mutations	mutation	NNS
cord-015935-r2wd1yfa	338	5	are	be	VBP
cord-015935-r2wd1yfa	338	6	very	very	RB
cord-015935-r2wd1yfa	338	7	rare	rare	JJ
cord-015935-r2wd1yfa	338	8	.	.	.
cord-015935-r2wd1yfa	339	1	For	for	IN
cord-015935-r2wd1yfa	339	2	example	example	NN
cord-015935-r2wd1yfa	339	3	,	,	,
cord-015935-r2wd1yfa	339	4	two	two	CD
cord-015935-r2wd1yfa	339	5	missense	missense	NN
cord-015935-r2wd1yfa	339	6	mutations	mutation	NNS
cord-015935-r2wd1yfa	339	7	were	be	VBD
cord-015935-r2wd1yfa	339	8	present	present	JJ
cord-015935-r2wd1yfa	339	9	in	in	IN
cord-015935-r2wd1yfa	339	10	4	4	CD
cord-015935-r2wd1yfa	339	11	of	of	IN
cord-015935-r2wd1yfa	339	12	264	264	CD
cord-015935-r2wd1yfa	339	13	(	(	-LRB-
cord-015935-r2wd1yfa	339	14	1.5	1.5	CD
cord-015935-r2wd1yfa	339	15	%	%	NN
cord-015935-r2wd1yfa	339	16	)	)	-RRB-
cord-015935-r2wd1yfa	339	17	individuals	individual	NNS
cord-015935-r2wd1yfa	339	18	with	with	IN
cord-015935-r2wd1yfa	339	19	autism	autism	NN
cord-015935-r2wd1yfa	339	20	compared	compare	VBN
cord-015935-r2wd1yfa	339	21	to	to	IN
cord-015935-r2wd1yfa	339	22	none	none	NN
cord-015935-r2wd1yfa	339	23	in	in	IN
cord-015935-r2wd1yfa	339	24	729	729	CD
cord-015935-r2wd1yfa	339	25	controls	control	NNS
cord-015935-r2wd1yfa	340	1	(	(	-LRB-
cord-015935-r2wd1yfa	340	2	Feng	Feng	NNP
cord-015935-r2wd1yfa	340	3	et	et	FW
cord-015935-r2wd1yfa	340	4	al	al	NNP
cord-015935-r2wd1yfa	340	5	.	.	NNP
cord-015935-r2wd1yfa	340	6	,	,	,
cord-015935-r2wd1yfa	340	7	2006	2006	CD
cord-015935-r2wd1yfa	340	8	)	)	-RRB-
cord-015935-r2wd1yfa	340	9	.	.	.
cord-015935-r2wd1yfa	341	1	However	however	RB
cord-015935-r2wd1yfa	341	2	,	,	,
cord-015935-r2wd1yfa	341	3	in	in	IN
cord-015935-r2wd1yfa	341	4	this	this	DT
cord-015935-r2wd1yfa	341	5	study	study	NN
cord-015935-r2wd1yfa	341	6	,	,	,
cord-015935-r2wd1yfa	341	7	missense	missense	NN
cord-015935-r2wd1yfa	341	8	mutations	mutation	NNS
cord-015935-r2wd1yfa	341	9	also	also	RB
cord-015935-r2wd1yfa	341	10	occurred	occur	VBD
cord-015935-r2wd1yfa	341	11	in	in	IN
cord-015935-r2wd1yfa	341	12	first	first	JJ
cord-015935-r2wd1yfa	341	13	-	-	HYPH
cord-015935-r2wd1yfa	341	14	degree	degree	NN
cord-015935-r2wd1yfa	341	15	relatives	relative	NNS
cord-015935-r2wd1yfa	341	16	who	who	WP
cord-015935-r2wd1yfa	341	17	displayed	display	VBD
cord-015935-r2wd1yfa	341	18	heterogeneous	heterogeneous	JJ
cord-015935-r2wd1yfa	341	19	phenotypes	phenotype	NNS
cord-015935-r2wd1yfa	341	20	such	such	JJ
cord-015935-r2wd1yfa	341	21	as	as	IN
cord-015935-r2wd1yfa	341	22	hyperactivity	hyperactivity	NN
cord-015935-r2wd1yfa	341	23	,	,	,
cord-015935-r2wd1yfa	341	24	depression	depression	NN
cord-015935-r2wd1yfa	341	25	,	,	,
cord-015935-r2wd1yfa	341	26	and	and	CC
cord-015935-r2wd1yfa	341	27	learning	learning	NN
cord-015935-r2wd1yfa	341	28	problems	problem	NNS
cord-015935-r2wd1yfa	341	29	.	.	.
cord-015935-r2wd1yfa	342	1	Incomplete	incomplete	JJ
cord-015935-r2wd1yfa	342	2	penetrance	penetrance	NN
cord-015935-r2wd1yfa	342	3	may	may	MD
cord-015935-r2wd1yfa	342	4	explain	explain	VB
cord-015935-r2wd1yfa	342	5	these	these	DT
cord-015935-r2wd1yfa	342	6	findings	finding	NNS
cord-015935-r2wd1yfa	342	7	,	,	,
cord-015935-r2wd1yfa	342	8	or	or	CC
cord-015935-r2wd1yfa	342	9	autism	autism	NN
cord-015935-r2wd1yfa	342	10	may	may	MD
cord-015935-r2wd1yfa	342	11	be	be	VB
cord-015935-r2wd1yfa	342	12	caused	cause	VBN
cord-015935-r2wd1yfa	342	13	by	by	IN
cord-015935-r2wd1yfa	342	14	neurexin	neurexin	NNP
cord-015935-r2wd1yfa	342	15	acting	act	VBG
cord-015935-r2wd1yfa	342	16	synergistically	synergistically	RB
cord-015935-r2wd1yfa	342	17	with	with	IN
cord-015935-r2wd1yfa	342	18	other	other	JJ
cord-015935-r2wd1yfa	342	19	susceptibility	susceptibility	NN
cord-015935-r2wd1yfa	342	20	genes	gene	NNS
cord-015935-r2wd1yfa	342	21	.	.	.
cord-015935-r2wd1yfa	343	1	Neurexin-1α	Neurexin-1α	NNP
cord-015935-r2wd1yfa	343	2	is	be	VBZ
cord-015935-r2wd1yfa	343	3	being	be	VBG
cord-015935-r2wd1yfa	343	4	intensely	intensely	RB
cord-015935-r2wd1yfa	343	5	studied	study	VBN
cord-015935-r2wd1yfa	343	6	in	in	IN
cord-015935-r2wd1yfa	343	7	mice	mouse	NNS
cord-015935-r2wd1yfa	343	8	as	as	IN
cord-015935-r2wd1yfa	343	9	deletion	deletion	NN
cord-015935-r2wd1yfa	343	10	in	in	IN
cord-015935-r2wd1yfa	343	11	this	this	DT
cord-015935-r2wd1yfa	343	12	molecule	molecule	NN
cord-015935-r2wd1yfa	343	13	resulted	result	VBD
cord-015935-r2wd1yfa	343	14	in	in	IN
cord-015935-r2wd1yfa	343	15	increased	increase	VBN
cord-015935-r2wd1yfa	343	16	repetitive	repetitive	JJ
cord-015935-r2wd1yfa	343	17	behavior	behavior	NN
cord-015935-r2wd1yfa	343	18	,	,	,
cord-015935-r2wd1yfa	343	19	whereas	whereas	IN
cord-015935-r2wd1yfa	343	20	social	social	JJ
cord-015935-r2wd1yfa	343	21	behavior	behavior	NN
cord-015935-r2wd1yfa	343	22	was	be	VBD
cord-015935-r2wd1yfa	343	23	relatively	relatively	RB
cord-015935-r2wd1yfa	343	24	intact	intact	JJ
cord-015935-r2wd1yfa	344	1	(	(	-LRB-
cord-015935-r2wd1yfa	344	2	Etherton	Etherton	NNP
cord-015935-r2wd1yfa	344	3	,	,	,
cord-015935-r2wd1yfa	344	4	Blaiss	Blaiss	NNP
cord-015935-r2wd1yfa	344	5	,	,	,
cord-015935-r2wd1yfa	344	6	Powell	Powell	NNP
cord-015935-r2wd1yfa	344	7	,	,	,
cord-015935-r2wd1yfa	344	8	&	&	CC
cord-015935-r2wd1yfa	344	9	Sudhof	Sudhof	NNP
cord-015935-r2wd1yfa	344	10	,	,	,
cord-015935-r2wd1yfa	344	11	2009	2009	CD
cord-015935-r2wd1yfa	344	12	)	)	-RRB-
cord-015935-r2wd1yfa	344	13	.	.	.
cord-015935-r2wd1yfa	345	1	This	this	DT
cord-015935-r2wd1yfa	345	2	implies	imply	VBZ
cord-015935-r2wd1yfa	345	3	an	an	DT
cord-015935-r2wd1yfa	345	4	animal	animal	NN
cord-015935-r2wd1yfa	345	5	model	model	NN
cord-015935-r2wd1yfa	345	6	for	for	IN
cord-015935-r2wd1yfa	345	7	a	a	DT
cord-015935-r2wd1yfa	345	8	discreet	discreet	JJ
cord-015935-r2wd1yfa	345	9	feature	feature	NN
cord-015935-r2wd1yfa	345	10	of	of	IN
cord-015935-r2wd1yfa	345	11	autistic	autistic	JJ
cord-015935-r2wd1yfa	345	12	behavior	behavior	NN
cord-015935-r2wd1yfa	345	13	(	(	-LRB-
cord-015935-r2wd1yfa	345	14	endotype	endotype	NNP
cord-015935-r2wd1yfa	345	15	)	)	-RRB-
cord-015935-r2wd1yfa	345	16	,	,	,
cord-015935-r2wd1yfa	345	17	as	as	IN
cord-015935-r2wd1yfa	345	18	discussed	discuss	VBN
cord-015935-r2wd1yfa	345	19	below	below	RB
cord-015935-r2wd1yfa	345	20	.	.	.
cord-015935-r2wd1yfa	346	1	Contactin	Contactin	NNP
cord-015935-r2wd1yfa	346	2	-	-	HYPH
cord-015935-r2wd1yfa	346	3	associated	associate	VBN
cord-015935-r2wd1yfa	346	4	protein	protein	NN
cord-015935-r2wd1yfa	346	5	-	-	HYPH
cord-015935-r2wd1yfa	346	6	like	like	JJ
cord-015935-r2wd1yfa	346	7	2	2	CD
cord-015935-r2wd1yfa	347	1	(	(	-LRB-
cord-015935-r2wd1yfa	347	2	CNTNAP2	CNTNAP2	NNP
cord-015935-r2wd1yfa	347	3	)	)	-RRB-
cord-015935-r2wd1yfa	347	4	is	be	VBZ
cord-015935-r2wd1yfa	347	5	a	a	DT
cord-015935-r2wd1yfa	347	6	member	member	NN
cord-015935-r2wd1yfa	347	7	of	of	IN
cord-015935-r2wd1yfa	347	8	the	the	DT
cord-015935-r2wd1yfa	347	9	neurexin	neurexin	NNP
cord-015935-r2wd1yfa	347	10	superfamily	superfamily	NNP
cord-015935-r2wd1yfa	347	11	which	which	WDT
cord-015935-r2wd1yfa	347	12	involves	involve	VBZ
cord-015935-r2wd1yfa	347	13	a	a	DT
cord-015935-r2wd1yfa	347	14	recessive	recessive	JJ
cord-015935-r2wd1yfa	347	15	frameshift	frameshift	NN
cord-015935-r2wd1yfa	347	16	mutation	mutation	NN
cord-015935-r2wd1yfa	347	17	on	on	IN
cord-015935-r2wd1yfa	347	18	chromosome	chromosome	NN
cord-015935-r2wd1yfa	347	19	7q35	7q35	CD
cord-015935-r2wd1yfa	347	20	.	.	.
cord-015935-r2wd1yfa	348	1	It	-PRON-	PRP
cord-015935-r2wd1yfa	348	2	is	be	VBZ
cord-015935-r2wd1yfa	348	3	one	one	CD
cord-015935-r2wd1yfa	348	4	of	of	IN
cord-015935-r2wd1yfa	348	5	the	the	DT
cord-015935-r2wd1yfa	348	6	largest	large	JJS
cord-015935-r2wd1yfa	348	7	genes	gene	NNS
cord-015935-r2wd1yfa	348	8	of	of	IN
cord-015935-r2wd1yfa	348	9	the	the	DT
cord-015935-r2wd1yfa	348	10	human	human	JJ
cord-015935-r2wd1yfa	348	11	genome	genome	NN
cord-015935-r2wd1yfa	348	12	and	and	CC
cord-015935-r2wd1yfa	348	13	encodes	encode	VBZ
cord-015935-r2wd1yfa	348	14	CASPR2	caspr2	PRP
cord-015935-r2wd1yfa	348	15	,	,	,
cord-015935-r2wd1yfa	348	16	a	a	DT
cord-015935-r2wd1yfa	348	17	transmembrane	transmembrane	NN
cord-015935-r2wd1yfa	348	18	scaffolding	scaffolding	NN
cord-015935-r2wd1yfa	348	19	protein	protein	NN
cord-015935-r2wd1yfa	348	20	.	.	.
cord-015935-r2wd1yfa	349	1	CNTNAP2	CNTNAP2	NNP
cord-015935-r2wd1yfa	349	2	has	have	VBZ
cord-015935-r2wd1yfa	349	3	been	be	VBN
cord-015935-r2wd1yfa	349	4	associated	associate	VBN
cord-015935-r2wd1yfa	349	5	with	with	IN
cord-015935-r2wd1yfa	349	6	cortical	cortical	JJ
cord-015935-r2wd1yfa	349	7	dysplasia	dysplasia	NN
cord-015935-r2wd1yfa	349	8	-	-	HYPH
cord-015935-r2wd1yfa	349	9	focal	focal	JJ
cord-015935-r2wd1yfa	349	10	epilepsy	epilepsy	NN
cord-015935-r2wd1yfa	349	11	in	in	IN
cord-015935-r2wd1yfa	349	12	an	an	DT
cord-015935-r2wd1yfa	349	13	Old	Old	NNP
cord-015935-r2wd1yfa	349	14	Order	order	NN
cord-015935-r2wd1yfa	349	15	Amish	amish	JJ
cord-015935-r2wd1yfa	349	16	community	community	NN
cord-015935-r2wd1yfa	349	17	(	(	-LRB-
cord-015935-r2wd1yfa	349	18	Strauss	Strauss	NNP
cord-015935-r2wd1yfa	349	19	et	et	NNP
cord-015935-r2wd1yfa	349	20	al	al	NNP
cord-015935-r2wd1yfa	349	21	.	.	NNP
cord-015935-r2wd1yfa	349	22	,	,	,
cord-015935-r2wd1yfa	349	23	2006	2006	CD
cord-015935-r2wd1yfa	349	24	)	)	-RRB-
cord-015935-r2wd1yfa	349	25	.	.	.
cord-015935-r2wd1yfa	350	1	Autism	Autism	NNP
cord-015935-r2wd1yfa	350	2	was	be	VBD
cord-015935-r2wd1yfa	350	3	present	present	JJ
cord-015935-r2wd1yfa	350	4	in	in	IN
cord-015935-r2wd1yfa	350	5	up	up	IN
cord-015935-r2wd1yfa	350	6	to	to	TO
cord-015935-r2wd1yfa	350	7	67	67	CD
cord-015935-r2wd1yfa	350	8	%	%	NN
cord-015935-r2wd1yfa	350	9	of	of	IN
cord-015935-r2wd1yfa	350	10	these	these	DT
cord-015935-r2wd1yfa	350	11	individuals	individual	NNS
cord-015935-r2wd1yfa	350	12	.	.	.
cord-015935-r2wd1yfa	351	1	We	-PRON-	PRP
cord-015935-r2wd1yfa	351	2	recently	recently	RB
cord-015935-r2wd1yfa	351	3	reported	report	VBD
cord-015935-r2wd1yfa	351	4	CNTNAP2	CNTNAP2	NNP
cord-015935-r2wd1yfa	351	5	in	in	IN
cord-015935-r2wd1yfa	351	6	an	an	DT
cord-015935-r2wd1yfa	351	7	Amish	amish	JJ
cord-015935-r2wd1yfa	351	8	girl	girl	NN
cord-015935-r2wd1yfa	351	9	with	with	IN
cord-015935-r2wd1yfa	351	10	epilepsy	epilepsy	NN
cord-015935-r2wd1yfa	351	11	and	and	CC
cord-015935-r2wd1yfa	351	12	autism	autism	NN
cord-015935-r2wd1yfa	351	13	who	who	WP
cord-015935-r2wd1yfa	351	14	also	also	RB
cord-015935-r2wd1yfa	351	15	showed	show	VBD
cord-015935-r2wd1yfa	351	16	hepatosplenomegaly	hepatosplenomegaly	NNP
cord-015935-r2wd1yfa	351	17	(	(	-LRB-
cord-015935-r2wd1yfa	351	18	Jackman	Jackman	NNP
cord-015935-r2wd1yfa	351	19	,	,	,
cord-015935-r2wd1yfa	351	20	Horn	Horn	NNP
cord-015935-r2wd1yfa	351	21	,	,	,
cord-015935-r2wd1yfa	351	22	Molleston	Molleston	NNP
cord-015935-r2wd1yfa	351	23	,	,	,
cord-015935-r2wd1yfa	351	24	&	&	CC
cord-015935-r2wd1yfa	351	25	Sokol	Sokol	NNP
cord-015935-r2wd1yfa	351	26	,	,	,
cord-015935-r2wd1yfa	351	27	2009	2009	CD
cord-015935-r2wd1yfa	351	28	)	)	-RRB-
cord-015935-r2wd1yfa	351	29	.	.	.
cord-015935-r2wd1yfa	352	1	CNTNAP2	CNTNAP2	NNP
cord-015935-r2wd1yfa	352	2	has	have	VBZ
cord-015935-r2wd1yfa	352	3	been	be	VBN
cord-015935-r2wd1yfa	352	4	associated	associate	VBN
cord-015935-r2wd1yfa	352	5	with	with	IN
cord-015935-r2wd1yfa	352	6	an	an	DT
cord-015935-r2wd1yfa	352	7	autism	autism	NN
cord-015935-r2wd1yfa	352	8	language	language	NN
cord-015935-r2wd1yfa	352	9	phenotype	phenotype	NN
cord-015935-r2wd1yfa	352	10	in	in	IN
cord-015935-r2wd1yfa	352	11	large	large	JJ
cord-015935-r2wd1yfa	352	12	studies	study	NNS
cord-015935-r2wd1yfa	352	13	of	of	IN
cord-015935-r2wd1yfa	352	14	non	non	JJ
cord-015935-r2wd1yfa	352	15	-	-	JJ
cord-015935-r2wd1yfa	352	16	Amish	amish	JJ
cord-015935-r2wd1yfa	352	17	individuals	individual	NNS
cord-015935-r2wd1yfa	352	18	(	(	-LRB-
cord-015935-r2wd1yfa	352	19	Alarcon	Alarcon	NNP
cord-015935-r2wd1yfa	352	20	et	et	NNP
cord-015935-r2wd1yfa	352	21	al	al	NNP
cord-015935-r2wd1yfa	352	22	.	.	NNP
cord-015935-r2wd1yfa	352	23	,	,	,
cord-015935-r2wd1yfa	352	24	2008	2008	CD
cord-015935-r2wd1yfa	352	25	)	)	-RRB-
cord-015935-r2wd1yfa	352	26	.	.	.
cord-015935-r2wd1yfa	353	1	Further	further	RB
cord-015935-r2wd1yfa	353	2	,	,	,
cord-015935-r2wd1yfa	353	3	stage	stage	NN
cord-015935-r2wd1yfa	353	4	two	two	CD
cord-015935-r2wd1yfa	353	5	of	of	IN
cord-015935-r2wd1yfa	353	6	this	this	DT
cord-015935-r2wd1yfa	353	7	investigation	investigation	NN
cord-015935-r2wd1yfa	353	8	showed	show	VBD
cord-015935-r2wd1yfa	353	9	that	that	IN
cord-015935-r2wd1yfa	353	10	CNTNAP2	CNTNAP2	NNP
cord-015935-r2wd1yfa	353	11	was	be	VBD
cord-015935-r2wd1yfa	353	12	expressed	express	VBN
cord-015935-r2wd1yfa	353	13	in	in	IN
cord-015935-r2wd1yfa	353	14	the	the	DT
cord-015935-r2wd1yfa	353	15	language	language	NN
cord-015935-r2wd1yfa	353	16	centers	center	NNS
cord-015935-r2wd1yfa	353	17	(	(	-LRB-
cord-015935-r2wd1yfa	353	18	frontal	frontal	JJ
cord-015935-r2wd1yfa	353	19	and	and	CC
cord-015935-r2wd1yfa	353	20	anterior	anterior	JJ
cord-015935-r2wd1yfa	353	21	temporal	temporal	JJ
cord-015935-r2wd1yfa	353	22	lobes	lobe	NNS
cord-015935-r2wd1yfa	353	23	)	)	-RRB-
cord-015935-r2wd1yfa	353	24	of	of	IN
cord-015935-r2wd1yfa	353	25	fetal	fetal	JJ
cord-015935-r2wd1yfa	353	26	brain	brain	NN
cord-015935-r2wd1yfa	353	27	(	(	-LRB-
cord-015935-r2wd1yfa	353	28	Alarcon	Alarcon	NNP
cord-015935-r2wd1yfa	353	29	et	et	NNP
cord-015935-r2wd1yfa	353	30	al	al	NNP
cord-015935-r2wd1yfa	353	31	.	.	NNP
cord-015935-r2wd1yfa	353	32	,	,	,
cord-015935-r2wd1yfa	353	33	2008	2008	CD
cord-015935-r2wd1yfa	353	34	)	)	-RRB-
cord-015935-r2wd1yfa	353	35	.	.	.
cord-015935-r2wd1yfa	354	1	It	-PRON-	PRP
cord-015935-r2wd1yfa	354	2	has	have	VBZ
cord-015935-r2wd1yfa	354	3	been	be	VBN
cord-015935-r2wd1yfa	354	4	recommended	recommend	VBN
cord-015935-r2wd1yfa	354	5	that	that	IN
cord-015935-r2wd1yfa	354	6	Amish	amish	JJ
cord-015935-r2wd1yfa	354	7	children	child	NNS
cord-015935-r2wd1yfa	354	8	presenting	present	VBG
cord-015935-r2wd1yfa	354	9	with	with	IN
cord-015935-r2wd1yfa	354	10	autism	autism	NN
cord-015935-r2wd1yfa	354	11	should	should	MD
cord-015935-r2wd1yfa	354	12	be	be	VB
cord-015935-r2wd1yfa	354	13	tested	test	VBN
cord-015935-r2wd1yfa	354	14	for	for	IN
cord-015935-r2wd1yfa	354	15	CNTNAP2	CNTNAP2	NNP
cord-015935-r2wd1yfa	354	16	gene	gene	NN
cord-015935-r2wd1yfa	354	17	mutation	mutation	NN
cord-015935-r2wd1yfa	354	18	(	(	-LRB-
cord-015935-r2wd1yfa	354	19	Strauss	Strauss	NNP
cord-015935-r2wd1yfa	354	20	,	,	,
cord-015935-r2wd1yfa	354	21	personal	personal	JJ
cord-015935-r2wd1yfa	354	22	communication	communication	NN
cord-015935-r2wd1yfa	354	23	)	)	-RRB-
cord-015935-r2wd1yfa	354	24	.	.	.
cord-015935-r2wd1yfa	355	1	This	this	DT
cord-015935-r2wd1yfa	355	2	work	work	NN
cord-015935-r2wd1yfa	355	3	again	again	RB
cord-015935-r2wd1yfa	355	4	supports	support	VBZ
cord-015935-r2wd1yfa	355	5	a	a	DT
cord-015935-r2wd1yfa	355	6	language	language	NN
cord-015935-r2wd1yfa	355	7	function	function	NN
cord-015935-r2wd1yfa	355	8	associated	associate	VBN
cord-015935-r2wd1yfa	355	9	with	with	IN
cord-015935-r2wd1yfa	355	10	chromosome	chromosome	NN
cord-015935-r2wd1yfa	355	11	7	7	CD
cord-015935-r2wd1yfa	355	12	.	.	.
cord-015935-r2wd1yfa	356	1	Methyl	methyl	NN
cord-015935-r2wd1yfa	356	2	-	-	HYPH
cord-015935-r2wd1yfa	356	3	CpG	cpg	NN
cord-015935-r2wd1yfa	356	4	-	-	HYPH
cord-015935-r2wd1yfa	356	5	binding	bind	VBG
cord-015935-r2wd1yfa	356	6	protein	protein	NN
cord-015935-r2wd1yfa	356	7	2	2	CD
cord-015935-r2wd1yfa	357	1	(	(	-LRB-
cord-015935-r2wd1yfa	357	2	MeCP2	mecp2	NN
cord-015935-r2wd1yfa	357	3	)	)	-RRB-
cord-015935-r2wd1yfa	357	4	works	work	VBZ
cord-015935-r2wd1yfa	357	5	as	as	IN
cord-015935-r2wd1yfa	357	6	a	a	DT
cord-015935-r2wd1yfa	357	7	transcriptional	transcriptional	JJ
cord-015935-r2wd1yfa	357	8	repressor	repressor	NN
cord-015935-r2wd1yfa	357	9	within	within	IN
cord-015935-r2wd1yfa	357	10	gene	gene	NN
cord-015935-r2wd1yfa	357	11	-	-	HYPH
cord-015935-r2wd1yfa	357	12	promoting	promote	VBG
cord-015935-r2wd1yfa	357	13	regions	region	NNS
cord-015935-r2wd1yfa	357	14	involved	involve	VBN
cord-015935-r2wd1yfa	357	15	in	in	IN
cord-015935-r2wd1yfa	357	16	chromatin	chromatin	NN
cord-015935-r2wd1yfa	357	17	repression	repression	NN
cord-015935-r2wd1yfa	357	18	.	.	.
cord-015935-r2wd1yfa	358	1	This	this	DT
cord-015935-r2wd1yfa	358	2	gene	gene	NN
cord-015935-r2wd1yfa	358	3	is	be	VBZ
cord-015935-r2wd1yfa	358	4	located	locate	VBN
cord-015935-r2wd1yfa	358	5	on	on	IN
cord-015935-r2wd1yfa	358	6	chromosome	chromosome	NN
cord-015935-r2wd1yfa	358	7	Xq28	xq28	NN
cord-015935-r2wd1yfa	358	8	and	and	CC
cord-015935-r2wd1yfa	358	9	shows	show	VBZ
cord-015935-r2wd1yfa	358	10	mutation	mutation	NN
cord-015935-r2wd1yfa	358	11	in	in	IN
cord-015935-r2wd1yfa	358	12	80	80	CD
cord-015935-r2wd1yfa	358	13	%	%	NN
cord-015935-r2wd1yfa	358	14	of	of	IN
cord-015935-r2wd1yfa	358	15	females	female	NNS
cord-015935-r2wd1yfa	358	16	with	with	IN
cord-015935-r2wd1yfa	358	17	Rett	Rett	NNP
cord-015935-r2wd1yfa	358	18	syndrome	syndrome	NN
cord-015935-r2wd1yfa	358	19	(	(	-LRB-
cord-015935-r2wd1yfa	358	20	pervasive	pervasive	JJ
cord-015935-r2wd1yfa	358	21	developmental	developmental	JJ
cord-015935-r2wd1yfa	358	22	disorder	disorder	NN
cord-015935-r2wd1yfa	358	23	,	,	,
cord-015935-r2wd1yfa	358	24	acquired	acquire	VBN
cord-015935-r2wd1yfa	358	25	microcephaly	microcephaly	NNS
cord-015935-r2wd1yfa	358	26	,	,	,
cord-015935-r2wd1yfa	358	27	epilepsy	epilepsy	NN
cord-015935-r2wd1yfa	358	28	,	,	,
cord-015935-r2wd1yfa	358	29	and	and	CC
cord-015935-r2wd1yfa	358	30	loss	loss	NN
cord-015935-r2wd1yfa	358	31	of	of	IN
cord-015935-r2wd1yfa	358	32	hand	hand	NN
cord-015935-r2wd1yfa	358	33	function	function	NN
cord-015935-r2wd1yfa	358	34	)	)	-RRB-
cord-015935-r2wd1yfa	358	35	.	.	.
cord-015935-r2wd1yfa	359	1	This	this	DT
cord-015935-r2wd1yfa	359	2	gene	gene	NN
cord-015935-r2wd1yfa	359	3	has	have	VBZ
cord-015935-r2wd1yfa	359	4	been	be	VBN
cord-015935-r2wd1yfa	359	5	studied	study	VBN
cord-015935-r2wd1yfa	359	6	in	in	IN
cord-015935-r2wd1yfa	359	7	children	child	NNS
cord-015935-r2wd1yfa	359	8	with	with	IN
cord-015935-r2wd1yfa	359	9	autism	autism	NN
cord-015935-r2wd1yfa	359	10	,	,	,
cord-015935-r2wd1yfa	359	11	and	and	CC
cord-015935-r2wd1yfa	359	12	MeCP2	mecp2	NN
cord-015935-r2wd1yfa	359	13	mutations	mutation	NNS
cord-015935-r2wd1yfa	359	14	are	be	VBP
cord-015935-r2wd1yfa	359	15	considered	consider	VBN
cord-015935-r2wd1yfa	359	16	to	to	TO
cord-015935-r2wd1yfa	359	17	be	be	VB
cord-015935-r2wd1yfa	359	18	rare	rare	JJ
cord-015935-r2wd1yfa	359	19	(	(	-LRB-
cord-015935-r2wd1yfa	359	20	0.8	0.8	CD
cord-015935-r2wd1yfa	359	21	-	-	SYM
cord-015935-r2wd1yfa	359	22	1.3	1.3	CD
cord-015935-r2wd1yfa	359	23	%	%	NN
cord-015935-r2wd1yfa	359	24	)	)	-RRB-
cord-015935-r2wd1yfa	359	25	in	in	IN
cord-015935-r2wd1yfa	359	26	females	female	NNS
cord-015935-r2wd1yfa	359	27	with	with	IN
cord-015935-r2wd1yfa	359	28	autism	autism	NN
cord-015935-r2wd1yfa	359	29	.	.	.
cord-015935-r2wd1yfa	360	1	Interestingly	interestingly	RB
cord-015935-r2wd1yfa	360	2	,	,	,
cord-015935-r2wd1yfa	360	3	autism	autism	NN
cord-015935-r2wd1yfa	360	4	and	and	CC
cord-015935-r2wd1yfa	360	5	Rett	Rett	NNP
cord-015935-r2wd1yfa	360	6	syndrome	syndrome	NN
cord-015935-r2wd1yfa	360	7	share	share	VBP
cord-015935-r2wd1yfa	360	8	some	some	DT
cord-015935-r2wd1yfa	360	9	similarities	similarity	NNS
cord-015935-r2wd1yfa	360	10	at	at	IN
cord-015935-r2wd1yfa	360	11	the	the	DT
cord-015935-r2wd1yfa	360	12	phenotypic	phenotypic	NN
cord-015935-r2wd1yfa	360	13	and	and	CC
cord-015935-r2wd1yfa	360	14	pathogenic	pathogenic	JJ
cord-015935-r2wd1yfa	360	15	levels	level	NNS
cord-015935-r2wd1yfa	360	16	,	,	,
cord-015935-r2wd1yfa	360	17	and	and	CC
cord-015935-r2wd1yfa	360	18	both	both	DT
cord-015935-r2wd1yfa	360	19	disorders	disorder	NNS
cord-015935-r2wd1yfa	360	20	were	be	VBD
cord-015935-r2wd1yfa	360	21	proposed	propose	VBN
cord-015935-r2wd1yfa	360	22	to	to	TO
cord-015935-r2wd1yfa	360	23	result	result	VB
cord-015935-r2wd1yfa	360	24	from	from	IN
cord-015935-r2wd1yfa	360	25	disruption	disruption	NN
cord-015935-r2wd1yfa	360	26	of	of	IN
cord-015935-r2wd1yfa	360	27	postnatal	postnatal	JJ
cord-015935-r2wd1yfa	360	28	or	or	CC
cord-015935-r2wd1yfa	360	29	experience	experience	NN
cord-015935-r2wd1yfa	360	30	-	-	HYPH
cord-015935-r2wd1yfa	360	31	dependent	dependent	JJ
cord-015935-r2wd1yfa	360	32	synaptic	synaptic	JJ
cord-015935-r2wd1yfa	360	33	plasticity	plasticity	NN
cord-015935-r2wd1yfa	360	34	(	(	-LRB-
cord-015935-r2wd1yfa	360	35	Zoghbi	Zoghbi	NNP
cord-015935-r2wd1yfa	360	36	,	,	,
cord-015935-r2wd1yfa	360	37	2003	2003	CD
cord-015935-r2wd1yfa	360	38	)	)	-RRB-
cord-015935-r2wd1yfa	360	39	.	.	.
cord-015935-r2wd1yfa	361	1	Among	among	IN
cord-015935-r2wd1yfa	361	2	the	the	DT
cord-015935-r2wd1yfa	361	3	Rett	Rett	NNP
cord-015935-r2wd1yfa	361	4	mutations	mutation	NNS
cord-015935-r2wd1yfa	361	5	reported	report	VBN
cord-015935-r2wd1yfa	361	6	are	be	VBP
cord-015935-r2wd1yfa	361	7	a	a	DT
cord-015935-r2wd1yfa	361	8	frameshift	frameshift	NN
cord-015935-r2wd1yfa	361	9	mutation	mutation	NN
cord-015935-r2wd1yfa	361	10	,	,	,
cord-015935-r2wd1yfa	361	11	a	a	DT
cord-015935-r2wd1yfa	361	12	nonsense	nonsense	NN
cord-015935-r2wd1yfa	361	13	mutation	mutation	NN
cord-015935-r2wd1yfa	361	14	,	,	,
cord-015935-r2wd1yfa	361	15	and	and	CC
cord-015935-r2wd1yfa	361	16	additional	additional	JJ
cord-015935-r2wd1yfa	361	17	introns	intron	NNS
cord-015935-r2wd1yfa	361	18	(	(	-LRB-
cord-015935-r2wd1yfa	361	19	Lintas	Lintas	NNP
cord-015935-r2wd1yfa	361	20	&	&	CC
cord-015935-r2wd1yfa	361	21	Persico	Persico	NNP
cord-015935-r2wd1yfa	361	22	,	,	,
cord-015935-r2wd1yfa	361	23	2009	2009	CD
cord-015935-r2wd1yfa	361	24	)	)	-RRB-
cord-015935-r2wd1yfa	361	25	.	.	.
cord-015935-r2wd1yfa	362	1	observe	observe	VB
cord-015935-r2wd1yfa	362	2	that	that	IN
cord-015935-r2wd1yfa	362	3	MeCP2	mecp2	NN
cord-015935-r2wd1yfa	362	4	has	have	VBZ
cord-015935-r2wd1yfa	362	5	not	not	RB
cord-015935-r2wd1yfa	362	6	been	be	VBN
cord-015935-r2wd1yfa	362	7	associated	associate	VBN
cord-015935-r2wd1yfa	362	8	with	with	IN
cord-015935-r2wd1yfa	362	9	idiopathic	idiopathic	JJ
cord-015935-r2wd1yfa	362	10	autism	autism	NN
cord-015935-r2wd1yfa	362	11	in	in	IN
cord-015935-r2wd1yfa	362	12	males	male	NNS
cord-015935-r2wd1yfa	362	13	so	so	IN
cord-015935-r2wd1yfa	362	14	that	that	IN
cord-015935-r2wd1yfa	362	15	this	this	DT
cord-015935-r2wd1yfa	362	16	gene	gene	NN
cord-015935-r2wd1yfa	362	17	test	test	NN
cord-015935-r2wd1yfa	362	18	is	be	VBZ
cord-015935-r2wd1yfa	362	19	recommended	recommend	VBN
cord-015935-r2wd1yfa	362	20	only	only	RB
cord-015935-r2wd1yfa	362	21	for	for	IN
cord-015935-r2wd1yfa	362	22	females	female	NNS
cord-015935-r2wd1yfa	362	23	with	with	IN
cord-015935-r2wd1yfa	362	24	autism	autism	NN
cord-015935-r2wd1yfa	362	25	.	.	.
cord-015935-r2wd1yfa	363	1	Linkage	linkage	NN
cord-015935-r2wd1yfa	363	2	studies	study	NNS
cord-015935-r2wd1yfa	363	3	involve	involve	VBP
cord-015935-r2wd1yfa	363	4	determining	determine	VBG
cord-015935-r2wd1yfa	363	5	whether	whether	IN
cord-015935-r2wd1yfa	363	6	the	the	DT
cord-015935-r2wd1yfa	363	7	transmission	transmission	NN
cord-015935-r2wd1yfa	363	8	of	of	IN
cord-015935-r2wd1yfa	363	9	a	a	DT
cord-015935-r2wd1yfa	363	10	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	363	11	segment	segment	NN
cord-015935-r2wd1yfa	363	12	from	from	IN
cord-015935-r2wd1yfa	363	13	one	one	CD
cord-015935-r2wd1yfa	363	14	generation	generation	NN
cord-015935-r2wd1yfa	363	15	to	to	IN
cord-015935-r2wd1yfa	363	16	another	another	DT
cord-015935-r2wd1yfa	363	17	coincides	coincides	NN
cord-015935-r2wd1yfa	363	18	with	with	IN
cord-015935-r2wd1yfa	363	19	the	the	DT
cord-015935-r2wd1yfa	363	20	presence	presence	NN
cord-015935-r2wd1yfa	363	21	of	of	IN
cord-015935-r2wd1yfa	363	22	the	the	DT
cord-015935-r2wd1yfa	363	23	phenotype	phenotype	NN
cord-015935-r2wd1yfa	363	24	of	of	IN
cord-015935-r2wd1yfa	363	25	interest	interest	NN
cord-015935-r2wd1yfa	363	26	(	(	-LRB-
cord-015935-r2wd1yfa	363	27	Gupta	Gupta	NNP
cord-015935-r2wd1yfa	363	28	&	&	CC
cord-015935-r2wd1yfa	363	29	State	State	NNP
cord-015935-r2wd1yfa	363	30	,	,	,
cord-015935-r2wd1yfa	363	31	2007	2007	CD
cord-015935-r2wd1yfa	363	32	)	)	-RRB-
cord-015935-r2wd1yfa	363	33	.	.	.
cord-015935-r2wd1yfa	364	1	Linkage	linkage	NN
cord-015935-r2wd1yfa	364	2	can	can	MD
cord-015935-r2wd1yfa	364	3	be	be	VB
cord-015935-r2wd1yfa	364	4	utilized	utilize	VBN
cord-015935-r2wd1yfa	364	5	in	in	IN
cord-015935-r2wd1yfa	364	6	Mendelian	mendelian	JJ
cord-015935-r2wd1yfa	364	7	inherited	inherit	VBN
cord-015935-r2wd1yfa	364	8	conditions	condition	NNS
cord-015935-r2wd1yfa	364	9	and	and	CC
cord-015935-r2wd1yfa	364	10	can	can	MD
cord-015935-r2wd1yfa	364	11	also	also	RB
cord-015935-r2wd1yfa	364	12	be	be	VB
cord-015935-r2wd1yfa	364	13	used	use	VBN
cord-015935-r2wd1yfa	364	14	to	to	TO
cord-015935-r2wd1yfa	364	15	study	study	VB
cord-015935-r2wd1yfa	364	16	complex	complex	JJ
cord-015935-r2wd1yfa	364	17	conditions	condition	NNS
cord-015935-r2wd1yfa	364	18	such	such	JJ
cord-015935-r2wd1yfa	364	19	as	as	IN
cord-015935-r2wd1yfa	364	20	in	in	IN
cord-015935-r2wd1yfa	364	21	autism	autism	NN
cord-015935-r2wd1yfa	364	22	when	when	WRB
cord-015935-r2wd1yfa	364	23	Mendelian	mendelian	JJ
cord-015935-r2wd1yfa	364	24	inheritance	inheritance	NN
cord-015935-r2wd1yfa	364	25	is	be	VBZ
cord-015935-r2wd1yfa	364	26	unlikely	unlikely	JJ
cord-015935-r2wd1yfa	364	27	,	,	,
cord-015935-r2wd1yfa	364	28	and	and	CC
cord-015935-r2wd1yfa	364	29	there	there	EX
cord-015935-r2wd1yfa	364	30	is	be	VBZ
cord-015935-r2wd1yfa	364	31	no	no	DT
cord-015935-r2wd1yfa	364	32	hypotheses	hypothesis	NNS
cord-015935-r2wd1yfa	364	33	regarding	regard	VBG
cord-015935-r2wd1yfa	364	34	the	the	DT
cord-015935-r2wd1yfa	364	35	specific	specific	JJ
cord-015935-r2wd1yfa	364	36	nature	nature	NN
cord-015935-r2wd1yfa	364	37	of	of	IN
cord-015935-r2wd1yfa	364	38	transmission	transmission	NN
cord-015935-r2wd1yfa	364	39	.	.	.
cord-015935-r2wd1yfa	365	1	Linkage	linkage	NN
cord-015935-r2wd1yfa	365	2	studies	study	NNS
cord-015935-r2wd1yfa	365	3	can	can	MD
cord-015935-r2wd1yfa	365	4	be	be	VB
cord-015935-r2wd1yfa	365	5	grouped	group	VBN
cord-015935-r2wd1yfa	365	6	into	into	IN
cord-015935-r2wd1yfa	365	7	two	two	CD
cord-015935-r2wd1yfa	365	8	types	type	NNS
cord-015935-r2wd1yfa	365	9	-the	-the	NFP
cord-015935-r2wd1yfa	365	10	conventional	conventional	JJ
cord-015935-r2wd1yfa	365	11	study	study	NN
cord-015935-r2wd1yfa	365	12	of	of	IN
cord-015935-r2wd1yfa	365	13	a	a	DT
cord-015935-r2wd1yfa	365	14	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	365	15	region	region	NN
cord-015935-r2wd1yfa	365	16	of	of	IN
cord-015935-r2wd1yfa	365	17	interest	interest	NN
cord-015935-r2wd1yfa	365	18	in	in	IN
cord-015935-r2wd1yfa	365	19	affected	affect	VBN
cord-015935-r2wd1yfa	365	20	sibling	sibling	NN
cord-015935-r2wd1yfa	365	21	-	-	HYPH
cord-015935-r2wd1yfa	365	22	pairs	pair	NNS
cord-015935-r2wd1yfa	365	23	from	from	IN
cord-015935-r2wd1yfa	365	24	multiplex	multiplex	JJ
cord-015935-r2wd1yfa	365	25	families	family	NNS
cord-015935-r2wd1yfa	365	26	and	and	CC
cord-015935-r2wd1yfa	365	27	the	the	DT
cord-015935-r2wd1yfa	365	28	more	more	RBR
cord-015935-r2wd1yfa	365	29	recent	recent	JJ
cord-015935-r2wd1yfa	365	30	genome	genome	NN
cord-015935-r2wd1yfa	365	31	-	-	HYPH
cord-015935-r2wd1yfa	365	32	wide	wide	JJ
cord-015935-r2wd1yfa	365	33	linkage	linkage	NN
cord-015935-r2wd1yfa	365	34	analysis	analysis	NN
cord-015935-r2wd1yfa	365	35	in	in	IN
cord-015935-r2wd1yfa	365	36	which	which	WDT
cord-015935-r2wd1yfa	365	37	every	every	DT
cord-015935-r2wd1yfa	365	38	chromosome	chromosome	NN
cord-015935-r2wd1yfa	365	39	is	be	VBZ
cord-015935-r2wd1yfa	365	40	evaluated	evaluate	VBN
cord-015935-r2wd1yfa	365	41	simultaneously	simultaneously	RB
cord-015935-r2wd1yfa	365	42	.	.	.
cord-015935-r2wd1yfa	366	1	In	in	IN
cord-015935-r2wd1yfa	366	2	the	the	DT
cord-015935-r2wd1yfa	366	3	sib	sib	JJ
cord-015935-r2wd1yfa	366	4	-	-	JJ
cord-015935-r2wd1yfa	366	5	pair	pair	JJ
cord-015935-r2wd1yfa	366	6	study	study	NN
cord-015935-r2wd1yfa	366	7	method	method	NN
cord-015935-r2wd1yfa	366	8	,	,	,
cord-015935-r2wd1yfa	366	9	siblings	sibling	NNS
cord-015935-r2wd1yfa	366	10	with	with	IN
cord-015935-r2wd1yfa	366	11	autism	autism	NN
cord-015935-r2wd1yfa	366	12	are	be	VBP
cord-015935-r2wd1yfa	366	13	evaluated	evaluate	VBN
cord-015935-r2wd1yfa	366	14	to	to	TO
cord-015935-r2wd1yfa	366	15	determine	determine	VB
cord-015935-r2wd1yfa	366	16	whether	whether	IN
cord-015935-r2wd1yfa	366	17	they	-PRON-	PRP
cord-015935-r2wd1yfa	366	18	share	share	VBP
cord-015935-r2wd1yfa	366	19	any	any	DT
cord-015935-r2wd1yfa	366	20	regions	region	NNS
cord-015935-r2wd1yfa	366	21	of	of	IN
cord-015935-r2wd1yfa	366	22	the	the	DT
cord-015935-r2wd1yfa	366	23	genome	genome	NN
cord-015935-r2wd1yfa	366	24	more	more	RBR
cord-015935-r2wd1yfa	366	25	frequently	frequently	RB
cord-015935-r2wd1yfa	366	26	than	than	IN
cord-015935-r2wd1yfa	366	27	would	would	MD
cord-015935-r2wd1yfa	366	28	be	be	VB
cord-015935-r2wd1yfa	366	29	expected	expect	VBN
cord-015935-r2wd1yfa	366	30	by	by	IN
cord-015935-r2wd1yfa	366	31	chance	chance	NN
cord-015935-r2wd1yfa	366	32	.	.	.
cord-015935-r2wd1yfa	367	1	Genomic	genomic	JJ
cord-015935-r2wd1yfa	367	2	wide	wide	JJ
cord-015935-r2wd1yfa	367	3	association	association	NN
cord-015935-r2wd1yfa	367	4	studies	study	NNS
cord-015935-r2wd1yfa	367	5	compare	compare	VBP
cord-015935-r2wd1yfa	367	6	genetic	genetic	JJ
cord-015935-r2wd1yfa	367	7	risk	risk	NN
cord-015935-r2wd1yfa	367	8	factors	factor	NNS
cord-015935-r2wd1yfa	367	9	in	in	IN
cord-015935-r2wd1yfa	367	10	the	the	DT
cord-015935-r2wd1yfa	367	11	form	form	NN
cord-015935-r2wd1yfa	367	12	of	of	IN
cord-015935-r2wd1yfa	367	13	specific	specific	JJ
cord-015935-r2wd1yfa	367	14	genetic	genetic	JJ
cord-015935-r2wd1yfa	367	15	markers	marker	NNS
cord-015935-r2wd1yfa	367	16	in	in	IN
cord-015935-r2wd1yfa	367	17	cases	case	NNS
cord-015935-r2wd1yfa	367	18	and	and	CC
cord-015935-r2wd1yfa	367	19	controls	control	NNS
cord-015935-r2wd1yfa	367	20	.	.	.
cord-015935-r2wd1yfa	368	1	These	these	DT
cord-015935-r2wd1yfa	368	2	markers	marker	NNS
cord-015935-r2wd1yfa	368	3	are	be	VBP
cord-015935-r2wd1yfa	368	4	distributed	distribute	VBN
cord-015935-r2wd1yfa	368	5	within	within	IN
cord-015935-r2wd1yfa	368	6	the	the	DT
cord-015935-r2wd1yfa	368	7	entire	entire	JJ
cord-015935-r2wd1yfa	368	8	genome	genome	NN
cord-015935-r2wd1yfa	368	9	rather	rather	RB
cord-015935-r2wd1yfa	368	10	than	than	IN
cord-015935-r2wd1yfa	368	11	limited	limit	VBN
cord-015935-r2wd1yfa	368	12	to	to	IN
cord-015935-r2wd1yfa	368	13	specific	specific	JJ
cord-015935-r2wd1yfa	368	14	gene	gene	NN
cord-015935-r2wd1yfa	368	15	regions	region	NNS
cord-015935-r2wd1yfa	368	16	such	such	JJ
cord-015935-r2wd1yfa	368	17	as	as	IN
cord-015935-r2wd1yfa	368	18	in	in	IN
cord-015935-r2wd1yfa	368	19	the	the	DT
cord-015935-r2wd1yfa	368	20	sib	sib	JJ
cord-015935-r2wd1yfa	368	21	-	-	JJ
cord-015935-r2wd1yfa	368	22	pair	pair	JJ
cord-015935-r2wd1yfa	368	23	method	method	NN
cord-015935-r2wd1yfa	368	24	.	.	.
cord-015935-r2wd1yfa	369	1	This	this	DT
cord-015935-r2wd1yfa	369	2	enables	enable	VBZ
cord-015935-r2wd1yfa	369	3	a	a	DT
cord-015935-r2wd1yfa	369	4	more	more	RBR
cord-015935-r2wd1yfa	369	5	unbiased	unbiased	JJ
cord-015935-r2wd1yfa	369	6	ascertainment	ascertainment	NN
cord-015935-r2wd1yfa	369	7	of	of	IN
cord-015935-r2wd1yfa	369	8	regions	region	NNS
cord-015935-r2wd1yfa	369	9	of	of	IN
cord-015935-r2wd1yfa	369	10	interest	interest	NN
cord-015935-r2wd1yfa	369	11	(	(	-LRB-
cord-015935-r2wd1yfa	369	12	Losh	Losh	NNP
cord-015935-r2wd1yfa	369	13	et	et	NNP
cord-015935-r2wd1yfa	369	14	al	al	NNP
cord-015935-r2wd1yfa	369	15	.	.	NNP
cord-015935-r2wd1yfa	369	16	,	,	,
cord-015935-r2wd1yfa	369	17	2008	2008	CD
cord-015935-r2wd1yfa	369	18	)	)	-RRB-
cord-015935-r2wd1yfa	369	19	.	.	.
cord-015935-r2wd1yfa	370	1	Several	several	JJ
cord-015935-r2wd1yfa	370	2	genome	genome	NN
cord-015935-r2wd1yfa	370	3	-	-	HYPH
cord-015935-r2wd1yfa	370	4	wide	wide	JJ
cord-015935-r2wd1yfa	370	5	scans	scan	NNS
cord-015935-r2wd1yfa	370	6	of	of	IN
cord-015935-r2wd1yfa	370	7	individuals	individual	NNS
cord-015935-r2wd1yfa	370	8	with	with	IN
cord-015935-r2wd1yfa	370	9	autism	autism	NN
cord-015935-r2wd1yfa	370	10	have	have	VBP
cord-015935-r2wd1yfa	370	11	been	be	VBN
cord-015935-r2wd1yfa	370	12	reported	report	VBN
cord-015935-r2wd1yfa	370	13	and	and	CC
cord-015935-r2wd1yfa	370	14	evidence	evidence	NN
cord-015935-r2wd1yfa	370	15	in	in	IN
cord-015935-r2wd1yfa	370	16	favor	favor	NN
cord-015935-r2wd1yfa	370	17	of	of	IN
cord-015935-r2wd1yfa	370	18	linkage	linkage	NN
cord-015935-r2wd1yfa	370	19	has	have	VBZ
cord-015935-r2wd1yfa	370	20	been	be	VBN
cord-015935-r2wd1yfa	370	21	determined	determine	VBN
cord-015935-r2wd1yfa	370	22	for	for	IN
cord-015935-r2wd1yfa	370	23	the	the	DT
cord-015935-r2wd1yfa	370	24	majority	majority	NN
cord-015935-r2wd1yfa	370	25	of	of	IN
cord-015935-r2wd1yfa	370	26	chromosomes	chromosome	NNS
cord-015935-r2wd1yfa	370	27	(	(	-LRB-
cord-015935-r2wd1yfa	370	28	Gupta	Gupta	NNP
cord-015935-r2wd1yfa	370	29	&	&	CC
cord-015935-r2wd1yfa	370	30	State	State	NNP
cord-015935-r2wd1yfa	370	31	,	,	,
cord-015935-r2wd1yfa	370	32	2007	2007	CD
cord-015935-r2wd1yfa	370	33	)	)	-RRB-
cord-015935-r2wd1yfa	370	34	.	.	.
cord-015935-r2wd1yfa	371	1	The	the	DT
cord-015935-r2wd1yfa	371	2	trouble	trouble	NN
cord-015935-r2wd1yfa	371	3	with	with	IN
cord-015935-r2wd1yfa	371	4	these	these	DT
cord-015935-r2wd1yfa	371	5	studies	study	NNS
cord-015935-r2wd1yfa	371	6	is	be	VBZ
cord-015935-r2wd1yfa	371	7	that	that	IN
cord-015935-r2wd1yfa	371	8	the	the	DT
cord-015935-r2wd1yfa	371	9	evidence	evidence	NN
cord-015935-r2wd1yfa	371	10	has	have	VBZ
cord-015935-r2wd1yfa	371	11	not	not	RB
cord-015935-r2wd1yfa	371	12	reached	reach	VBN
cord-015935-r2wd1yfa	371	13	statistical	statistical	JJ
cord-015935-r2wd1yfa	371	14	significance	significance	NN
cord-015935-r2wd1yfa	371	15	and	and	CC
cord-015935-r2wd1yfa	371	16	there	there	EX
cord-015935-r2wd1yfa	371	17	is	be	VBZ
cord-015935-r2wd1yfa	371	18	lack	lack	NN
cord-015935-r2wd1yfa	371	19	of	of	IN
cord-015935-r2wd1yfa	371	20	replication	replication	NN
cord-015935-r2wd1yfa	371	21	for	for	IN
cord-015935-r2wd1yfa	371	22	many	many	JJ
cord-015935-r2wd1yfa	371	23	of	of	IN
cord-015935-r2wd1yfa	371	24	these	these	DT
cord-015935-r2wd1yfa	371	25	findings	finding	NNS
cord-015935-r2wd1yfa	371	26	.	.	.
cord-015935-r2wd1yfa	372	1	Statistical	statistical	JJ
cord-015935-r2wd1yfa	372	2	significance	significance	NN
cord-015935-r2wd1yfa	372	3	is	be	VBZ
cord-015935-r2wd1yfa	372	4	calculated	calculate	VBN
cord-015935-r2wd1yfa	372	5	by	by	IN
cord-015935-r2wd1yfa	372	6	a	a	DT
cord-015935-r2wd1yfa	372	7	logarithm	logarithm	NN
cord-015935-r2wd1yfa	372	8	of	of	IN
cord-015935-r2wd1yfa	372	9	the	the	DT
cord-015935-r2wd1yfa	372	10	odds	odd	NNS
cord-015935-r2wd1yfa	372	11	(	(	-LRB-
cord-015935-r2wd1yfa	372	12	LOD	LOD	NNP
cord-015935-r2wd1yfa	372	13	)	)	-RRB-
cord-015935-r2wd1yfa	372	14	score	score	NN
cord-015935-r2wd1yfa	372	15	.	.	.
cord-015935-r2wd1yfa	373	1	This	this	DT
cord-015935-r2wd1yfa	373	2	score	score	NN
cord-015935-r2wd1yfa	373	3	represents	represent	VBZ
cord-015935-r2wd1yfa	373	4	the	the	DT
cord-015935-r2wd1yfa	373	5	logarithm	logarithm	NN
cord-015935-r2wd1yfa	373	6	of	of	IN
cord-015935-r2wd1yfa	373	7	the	the	DT
cord-015935-r2wd1yfa	373	8	likelihood	likelihood	NN
cord-015935-r2wd1yfa	373	9	ratio	ratio	NN
cord-015935-r2wd1yfa	373	10	of	of	IN
cord-015935-r2wd1yfa	373	11	observing	observe	VBG
cord-015935-r2wd1yfa	373	12	the	the	DT
cord-015935-r2wd1yfa	373	13	data	datum	NNS
cord-015935-r2wd1yfa	373	14	under	under	IN
cord-015935-r2wd1yfa	373	15	a	a	DT
cord-015935-r2wd1yfa	373	16	model	model	NN
cord-015935-r2wd1yfa	373	17	of	of	IN
cord-015935-r2wd1yfa	373	18	linkage	linkage	NN
cord-015935-r2wd1yfa	373	19	to	to	IN
cord-015935-r2wd1yfa	373	20	observing	observe	VBG
cord-015935-r2wd1yfa	373	21	the	the	DT
cord-015935-r2wd1yfa	373	22	data	datum	NNS
cord-015935-r2wd1yfa	373	23	under	under	IN
cord-015935-r2wd1yfa	373	24	a	a	DT
cord-015935-r2wd1yfa	373	25	model	model	NN
cord-015935-r2wd1yfa	373	26	of	of	IN
cord-015935-r2wd1yfa	373	27	free	free	JJ
cord-015935-r2wd1yfa	373	28	recombination	recombination	NN
cord-015935-r2wd1yfa	373	29	(	(	-LRB-
cord-015935-r2wd1yfa	373	30	no	no	DT
cord-015935-r2wd1yfa	373	31	linkage	linkage	NN
cord-015935-r2wd1yfa	373	32	)	)	-RRB-
cord-015935-r2wd1yfa	373	33	.	.	.
cord-015935-r2wd1yfa	374	1	An	an	DT
cord-015935-r2wd1yfa	374	2	LOD	lod	NN
cord-015935-r2wd1yfa	374	3	score	score	NN
cord-015935-r2wd1yfa	374	4	of	of	IN
cord-015935-r2wd1yfa	374	5	3.5	3.5	CD
cord-015935-r2wd1yfa	374	6	in	in	IN
cord-015935-r2wd1yfa	374	7	a	a	DT
cord-015935-r2wd1yfa	374	8	sib	sib	JJ
cord-015935-r2wd1yfa	374	9	-	-	JJ
cord-015935-r2wd1yfa	374	10	pair	pair	JJ
cord-015935-r2wd1yfa	374	11	analysis	analysis	NN
cord-015935-r2wd1yfa	374	12	is	be	VBZ
cord-015935-r2wd1yfa	374	13	considered	consider	VBN
cord-015935-r2wd1yfa	374	14	to	to	TO
cord-015935-r2wd1yfa	374	15	be	be	VB
cord-015935-r2wd1yfa	374	16	a	a	DT
cord-015935-r2wd1yfa	374	17	significant	significant	JJ
cord-015935-r2wd1yfa	374	18	linkage	linkage	NN
cord-015935-r2wd1yfa	374	19	(	(	-LRB-
cord-015935-r2wd1yfa	374	20	Lander	Lander	NNP
cord-015935-r2wd1yfa	374	21	&	&	CC
cord-015935-r2wd1yfa	374	22	Kruglyak	Kruglyak	NNP
cord-015935-r2wd1yfa	374	23	,	,	,
cord-015935-r2wd1yfa	374	24	1995	1995	CD
cord-015935-r2wd1yfa	374	25	)	)	-RRB-
cord-015935-r2wd1yfa	374	26	.	.	.
cord-015935-r2wd1yfa	375	1	Suggestive	suggestive	JJ
cord-015935-r2wd1yfa	375	2	linkage	linkage	NN
cord-015935-r2wd1yfa	375	3	is	be	VBZ
cord-015935-r2wd1yfa	375	4	an	an	DT
cord-015935-r2wd1yfa	375	5	LOD	lod	NN
cord-015935-r2wd1yfa	375	6	score	score	NN
cord-015935-r2wd1yfa	375	7	of	of	IN
cord-015935-r2wd1yfa	375	8	2.2	2.2	CD
cord-015935-r2wd1yfa	375	9	,	,	,
cord-015935-r2wd1yfa	375	10	and	and	CC
cord-015935-r2wd1yfa	375	11	a	a	DT
cord-015935-r2wd1yfa	375	12	highly	highly	RB
cord-015935-r2wd1yfa	375	13	significant	significant	JJ
cord-015935-r2wd1yfa	375	14	LOD	lod	NN
cord-015935-r2wd1yfa	375	15	score	score	NN
cord-015935-r2wd1yfa	375	16	is	be	VBZ
cord-015935-r2wd1yfa	375	17	5.4	5.4	CD
cord-015935-r2wd1yfa	375	18	.	.	.
cord-015935-r2wd1yfa	376	1	For	for	IN
cord-015935-r2wd1yfa	376	2	replication	replication	NN
cord-015935-r2wd1yfa	376	3	studies	study	NNS
cord-015935-r2wd1yfa	376	4	,	,	,
cord-015935-r2wd1yfa	376	5	the	the	DT
cord-015935-r2wd1yfa	376	6	replication	replication	NN
cord-015935-r2wd1yfa	376	7	threshold	threshold	NN
cord-015935-r2wd1yfa	376	8	is	be	VBZ
cord-015935-r2wd1yfa	376	9	considered	consider	VBN
cord-015935-r2wd1yfa	376	10	to	to	TO
cord-015935-r2wd1yfa	376	11	be	be	VB
cord-015935-r2wd1yfa	376	12	1.4	1.4	CD
cord-015935-r2wd1yfa	376	13	(	(	-LRB-
cord-015935-r2wd1yfa	376	14	Lander	Lander	NNP
cord-015935-r2wd1yfa	376	15	&	&	CC
cord-015935-r2wd1yfa	376	16	Kruglyak	Kruglyak	NNP
cord-015935-r2wd1yfa	376	17	,	,	,
cord-015935-r2wd1yfa	376	18	1995	1995	CD
cord-015935-r2wd1yfa	376	19	)	)	-RRB-
cord-015935-r2wd1yfa	376	20	.	.	.
cord-015935-r2wd1yfa	377	1	By	by	IN
cord-015935-r2wd1yfa	377	2	chance	chance	NN
cord-015935-r2wd1yfa	377	3	,	,	,
cord-015935-r2wd1yfa	377	4	one	one	PRP
cord-015935-r2wd1yfa	377	5	would	would	MD
cord-015935-r2wd1yfa	377	6	expect	expect	VB
cord-015935-r2wd1yfa	377	7	to	to	TO
cord-015935-r2wd1yfa	377	8	see	see	VB
cord-015935-r2wd1yfa	377	9	a	a	DT
cord-015935-r2wd1yfa	377	10	suggestive	suggestive	JJ
cord-015935-r2wd1yfa	377	11	linkage	linkage	NN
cord-015935-r2wd1yfa	377	12	peak	peak	NN
cord-015935-r2wd1yfa	377	13	once	once	IN
cord-015935-r2wd1yfa	377	14	every	every	DT
cord-015935-r2wd1yfa	377	15	genome	genome	NN
cord-015935-r2wd1yfa	377	16	scan	scan	NN
cord-015935-r2wd1yfa	377	17	or	or	CC
cord-015935-r2wd1yfa	377	18	a	a	DT
cord-015935-r2wd1yfa	377	19	significant	significant	JJ
cord-015935-r2wd1yfa	377	20	peak	peak	NN
cord-015935-r2wd1yfa	377	21	once	once	RB
cord-015935-r2wd1yfa	377	22	every	every	DT
cord-015935-r2wd1yfa	377	23	20	20	CD
cord-015935-r2wd1yfa	377	24	scans	scan	NNS
cord-015935-r2wd1yfa	377	25	(	(	-LRB-
cord-015935-r2wd1yfa	377	26	Gupta	Gupta	NNP
cord-015935-r2wd1yfa	377	27	&	&	CC
cord-015935-r2wd1yfa	377	28	State	State	NNP
cord-015935-r2wd1yfa	377	29	,	,	,
cord-015935-r2wd1yfa	377	30	2007	2007	CD
cord-015935-r2wd1yfa	377	31	)	)	-RRB-
cord-015935-r2wd1yfa	377	32	.	.	.
cord-015935-r2wd1yfa	378	1	Most	Most	JJS
cord-015935-r2wd1yfa	378	2	linkage	linkage	NN
cord-015935-r2wd1yfa	378	3	studies	study	NNS
cord-015935-r2wd1yfa	378	4	have	have	VBP
cord-015935-r2wd1yfa	378	5	identified	identify	VBN
cord-015935-r2wd1yfa	378	6	linkage	linkage	NN
cord-015935-r2wd1yfa	378	7	regions	region	NNS
cord-015935-r2wd1yfa	378	8	reaching	reach	VBG
cord-015935-r2wd1yfa	378	9	the	the	DT
cord-015935-r2wd1yfa	378	10	level	level	NN
cord-015935-r2wd1yfa	378	11	of	of	IN
cord-015935-r2wd1yfa	378	12	suggestive	suggestive	JJ
cord-015935-r2wd1yfa	378	13	linkage	linkage	NN
cord-015935-r2wd1yfa	378	14	at	at	IN
cord-015935-r2wd1yfa	378	15	best	well	RBS
cord-015935-r2wd1yfa	378	16	(	(	-LRB-
cord-015935-r2wd1yfa	378	17	Freitag	Freitag	NNP
cord-015935-r2wd1yfa	378	18	,	,	,
cord-015935-r2wd1yfa	378	19	2007	2007	CD
cord-015935-r2wd1yfa	378	20	)	)	-RRB-
cord-015935-r2wd1yfa	378	21	.	.	.
cord-015935-r2wd1yfa	379	1	Despite	despite	IN
cord-015935-r2wd1yfa	379	2	large	large	JJ
cord-015935-r2wd1yfa	379	3	increases	increase	NNS
cord-015935-r2wd1yfa	379	4	in	in	IN
cord-015935-r2wd1yfa	379	5	the	the	DT
cord-015935-r2wd1yfa	379	6	size	size	NN
cord-015935-r2wd1yfa	379	7	of	of	IN
cord-015935-r2wd1yfa	379	8	patient	patient	JJ
cord-015935-r2wd1yfa	379	9	cohorts	cohort	NNS
cord-015935-r2wd1yfa	379	10	,	,	,
cord-015935-r2wd1yfa	379	11	linkage	linkage	NN
cord-015935-r2wd1yfa	379	12	signals	signal	NNS
cord-015935-r2wd1yfa	379	13	have	have	VBP
cord-015935-r2wd1yfa	379	14	not	not	RB
cord-015935-r2wd1yfa	379	15	increased	increase	VBN
cord-015935-r2wd1yfa	379	16	significantly	significantly	RB
cord-015935-r2wd1yfa	379	17	with	with	IN
cord-015935-r2wd1yfa	379	18	sample	sample	NN
cord-015935-r2wd1yfa	379	19	size	size	NN
cord-015935-r2wd1yfa	379	20	(	(	-LRB-
cord-015935-r2wd1yfa	379	21	Abrahams	Abrahams	NNP
cord-015935-r2wd1yfa	379	22	&	&	CC
cord-015935-r2wd1yfa	379	23	Geschwind	Geschwind	NNP
cord-015935-r2wd1yfa	379	24	,	,	,
cord-015935-r2wd1yfa	379	25	2008	2008	CD
cord-015935-r2wd1yfa	379	26	)	)	-RRB-
cord-015935-r2wd1yfa	379	27	.	.	.
cord-015935-r2wd1yfa	380	1	Only	only	RB
cord-015935-r2wd1yfa	380	2	three	three	CD
cord-015935-r2wd1yfa	380	3	loci	locus	NNS
cord-015935-r2wd1yfa	380	4	(	(	-LRB-
cord-015935-r2wd1yfa	380	5	2q	2q	CD
cord-015935-r2wd1yfa	380	6	,	,	,
cord-015935-r2wd1yfa	380	7	7q	7q	CD
cord-015935-r2wd1yfa	380	8	,	,	,
cord-015935-r2wd1yfa	380	9	and	and	CC
cord-015935-r2wd1yfa	380	10	17q11	17q11	CD
cord-015935-r2wd1yfa	380	11	-	-	SYM
cord-015935-r2wd1yfa	380	12	17	17	CD
cord-015935-r2wd1yfa	380	13	)	)	-RRB-
cord-015935-r2wd1yfa	380	14	have	have	VBP
cord-015935-r2wd1yfa	380	15	been	be	VBN
cord-015935-r2wd1yfa	380	16	replicated	replicate	VBN
cord-015935-r2wd1yfa	380	17	for	for	IN
cord-015935-r2wd1yfa	380	18	nonsyndromic	nonsyndromic	NNP
cord-015935-r2wd1yfa	380	19	autism	autism	NNP
cord-015935-r2wd1yfa	380	20	and	and	CC
cord-015935-r2wd1yfa	380	21	are	be	VBP
cord-015935-r2wd1yfa	380	22	considered	consider	VBN
cord-015935-r2wd1yfa	380	23	to	to	TO
cord-015935-r2wd1yfa	380	24	have	have	VB
cord-015935-r2wd1yfa	380	25	genome	genome	NN
cord-015935-r2wd1yfa	380	26	-	-	HYPH
cord-015935-r2wd1yfa	380	27	wide	wide	JJ
cord-015935-r2wd1yfa	380	28	significance	significance	NN
cord-015935-r2wd1yfa	380	29	.	.	.
cord-015935-r2wd1yfa	381	1	Genomic	genomic	NN
cord-015935-r2wd1yfa	381	2	-	-	HYPH
cord-015935-r2wd1yfa	381	3	wide	wide	JJ
cord-015935-r2wd1yfa	381	4	screens	screen	NNS
cord-015935-r2wd1yfa	381	5	have	have	VBP
cord-015935-r2wd1yfa	381	6	engendered	engender	VBN
cord-015935-r2wd1yfa	381	7	great	great	JJ
cord-015935-r2wd1yfa	381	8	interest	interest	NN
cord-015935-r2wd1yfa	381	9	in	in	IN
cord-015935-r2wd1yfa	381	10	chromosome	chromosome	NN
cord-015935-r2wd1yfa	381	11	7q	7q	CD
cord-015935-r2wd1yfa	381	12	with	with	IN
cord-015935-r2wd1yfa	381	13	distinctive	distinctive	JJ
cord-015935-r2wd1yfa	381	14	peaks	peak	NNS
cord-015935-r2wd1yfa	381	15	involving	involve	VBG
cord-015935-r2wd1yfa	381	16	two	two	CD
cord-015935-r2wd1yfa	381	17	distinct	distinct	JJ
cord-015935-r2wd1yfa	381	18	regions	region	NNS
cord-015935-r2wd1yfa	381	19	:	:	:
cord-015935-r2wd1yfa	381	20	7q21	7q21	CD
cord-015935-r2wd1yfa	381	21	-	-	SYM
cord-015935-r2wd1yfa	381	22	22	22	CD
cord-015935-r2wd1yfa	381	23	and	and	CC
cord-015935-r2wd1yfa	381	24	7q32	7q32	CD
cord-015935-r2wd1yfa	381	25	-	-	SYM
cord-015935-r2wd1yfa	381	26	36	36	CD
cord-015935-r2wd1yfa	381	27	(	(	-LRB-
cord-015935-r2wd1yfa	381	28	International	International	NNP
cord-015935-r2wd1yfa	381	29	Molecular	Molecular	NNP
cord-015935-r2wd1yfa	381	30	Genetic	Genetic	NNP
cord-015935-r2wd1yfa	381	31	Study	Study	NNP
cord-015935-r2wd1yfa	381	32	of	of	IN
cord-015935-r2wd1yfa	381	33	Autism	Autism	NNP
cord-015935-r2wd1yfa	381	34	Consortium	Consortium	NNP
cord-015935-r2wd1yfa	381	35	-	-	HYPH
cord-015935-r2wd1yfa	381	36	IMGSAC	IMGSAC	NNP
cord-015935-r2wd1yfa	381	37	,	,	,
cord-015935-r2wd1yfa	381	38	1998	1998	CD
cord-015935-r2wd1yfa	381	39	;	;	:
cord-015935-r2wd1yfa	381	40	Collaborative	Collaborative	NNP
cord-015935-r2wd1yfa	381	41	Linkage	Linkage	NNP
cord-015935-r2wd1yfa	381	42	Study	Study	NNP
cord-015935-r2wd1yfa	381	43	of	of	IN
cord-015935-r2wd1yfa	381	44	Autism	Autism	NNP
cord-015935-r2wd1yfa	381	45	,	,	,
cord-015935-r2wd1yfa	381	46	2001	2001	CD
cord-015935-r2wd1yfa	381	47	)	)	-RRB-
cord-015935-r2wd1yfa	381	48	.	.	.
cord-015935-r2wd1yfa	382	1	As	as	IN
cord-015935-r2wd1yfa	382	2	chromosome	chromosome	NN
cord-015935-r2wd1yfa	382	3	7q	7q	CD
cord-015935-r2wd1yfa	382	4	has	have	VBZ
cord-015935-r2wd1yfa	382	5	been	be	VBN
cord-015935-r2wd1yfa	382	6	discussed	discuss	VBN
cord-015935-r2wd1yfa	382	7	in	in	IN
cord-015935-r2wd1yfa	382	8	section	section	NN
cord-015935-r2wd1yfa	382	9	"	"	``
cord-015935-r2wd1yfa	382	10	Cytogenetics	cytogenetic	NNS
cord-015935-r2wd1yfa	382	11	:	:	:
cord-015935-r2wd1yfa	382	12	Rare	Rare	NNP
cord-015935-r2wd1yfa	382	13	Mutations	Mutations	NNPS
cord-015935-r2wd1yfa	382	14	,	,	,
cord-015935-r2wd1yfa	382	15	"	"	''
cord-015935-r2wd1yfa	382	16	chromosome	chromosome	NN
cord-015935-r2wd1yfa	382	17	2	2	CD
cord-015935-r2wd1yfa	383	1	and	and	CC
cord-015935-r2wd1yfa	383	2	then	then	RB
cord-015935-r2wd1yfa	383	3	17q11	17q11	CD
cord-015935-r2wd1yfa	383	4	will	will	MD
cord-015935-r2wd1yfa	383	5	follow	follow	VB
cord-015935-r2wd1yfa	383	6	the	the	DT
cord-015935-r2wd1yfa	383	7	description	description	NN
cord-015935-r2wd1yfa	383	8	of	of	IN
cord-015935-r2wd1yfa	383	9	how	how	WRB
cord-015935-r2wd1yfa	383	10	linkage	linkage	NN
cord-015935-r2wd1yfa	383	11	studies	study	NNS
cord-015935-r2wd1yfa	383	12	led	lead	VBD
cord-015935-r2wd1yfa	383	13	to	to	IN
cord-015935-r2wd1yfa	383	14	the	the	DT
cord-015935-r2wd1yfa	383	15	discovery	discovery	NN
cord-015935-r2wd1yfa	383	16	of	of	IN
cord-015935-r2wd1yfa	383	17	the	the	DT
cord-015935-r2wd1yfa	383	18	gene	gene	NN
cord-015935-r2wd1yfa	383	19	loci	locus	NNS
cord-015935-r2wd1yfa	383	20	for	for	IN
cord-015935-r2wd1yfa	383	21	a	a	DT
cord-015935-r2wd1yfa	383	22	syndromic	syndromic	JJ
cord-015935-r2wd1yfa	383	23	form	form	NN
cord-015935-r2wd1yfa	383	24	of	of	IN
cord-015935-r2wd1yfa	383	25	autism	autism	NN
cord-015935-r2wd1yfa	383	26	:	:	:
cord-015935-r2wd1yfa	384	1	tuberous	tuberous	JJ
cord-015935-r2wd1yfa	384	2	sclerosis	sclerosis	NN
cord-015935-r2wd1yfa	384	3	complex	complex	NN
cord-015935-r2wd1yfa	384	4	(	(	-LRB-
cord-015935-r2wd1yfa	384	5	TSC	TSC	NNP
cord-015935-r2wd1yfa	384	6	)	)	-RRB-
cord-015935-r2wd1yfa	384	7	.	.	.
cord-015935-r2wd1yfa	385	1	The	the	DT
cord-015935-r2wd1yfa	385	2	sibling	sibling	NN
cord-015935-r2wd1yfa	385	3	-	-	HYPH
cord-015935-r2wd1yfa	385	4	pair	pair	NN
cord-015935-r2wd1yfa	385	5	from	from	IN
cord-015935-r2wd1yfa	385	6	multiplex	multiplex	JJ
cord-015935-r2wd1yfa	385	7	family	family	NN
cord-015935-r2wd1yfa	385	8	design	design	NN
cord-015935-r2wd1yfa	385	9	has	have	VBZ
cord-015935-r2wd1yfa	385	10	been	be	VBN
cord-015935-r2wd1yfa	385	11	used	use	VBN
cord-015935-r2wd1yfa	385	12	to	to	TO
cord-015935-r2wd1yfa	385	13	study	study	VB
cord-015935-r2wd1yfa	385	14	autism	autism	NN
cord-015935-r2wd1yfa	385	15	within	within	IN
cord-015935-r2wd1yfa	385	16	many	many	JJ
cord-015935-r2wd1yfa	385	17	genetic	genetic	JJ
cord-015935-r2wd1yfa	385	18	loci	locus	NNS
cord-015935-r2wd1yfa	385	19	,	,	,
cord-015935-r2wd1yfa	385	20	including	include	VBG
cord-015935-r2wd1yfa	385	21	those	those	DT
cord-015935-r2wd1yfa	385	22	involved	involve	VBN
cord-015935-r2wd1yfa	385	23	in	in	IN
cord-015935-r2wd1yfa	385	24	TSC	TSC	NNP
cord-015935-r2wd1yfa	385	25	;	;	:
cord-015935-r2wd1yfa	385	26	the	the	DT
cord-015935-r2wd1yfa	385	27	genomewide	genomewide	NNP
cord-015935-r2wd1yfa	385	28	linkage	linkage	NN
cord-015935-r2wd1yfa	385	29	analysis	analysis	NN
cord-015935-r2wd1yfa	385	30	has	have	VBZ
cord-015935-r2wd1yfa	385	31	detected	detect	VBN
cord-015935-r2wd1yfa	385	32	linkage	linkage	NN
cord-015935-r2wd1yfa	385	33	on	on	IN
cord-015935-r2wd1yfa	385	34	chromosomes	chromosome	NNS
cord-015935-r2wd1yfa	385	35	7q	7q	CD
cord-015935-r2wd1yfa	385	36	,	,	,
cord-015935-r2wd1yfa	385	37	2q	2q	CD
cord-015935-r2wd1yfa	385	38	,	,	,
cord-015935-r2wd1yfa	385	39	17q11	17q11	CD
cord-015935-r2wd1yfa	385	40	,	,	,
cord-015935-r2wd1yfa	385	41	and	and	CC
cord-015935-r2wd1yfa	385	42	novel	novel	NN
cord-015935-r2wd1yfa	385	43	loci	locus	NNS
cord-015935-r2wd1yfa	385	44	.	.	.
cord-015935-r2wd1yfa	386	1	Tuberous	Tuberous	NNP
cord-015935-r2wd1yfa	386	2	sclerosis	sclerosis	NN
cord-015935-r2wd1yfa	386	3	complex	complex	NN
cord-015935-r2wd1yfa	386	4	(	(	-LRB-
cord-015935-r2wd1yfa	386	5	TSC	TSC	NNP
cord-015935-r2wd1yfa	386	6	)	)	-RRB-
cord-015935-r2wd1yfa	386	7	is	be	VBZ
cord-015935-r2wd1yfa	386	8	a	a	DT
cord-015935-r2wd1yfa	386	9	neurodevelopmental	neurodevelopmental	JJ
cord-015935-r2wd1yfa	386	10	disorder	disorder	NN
cord-015935-r2wd1yfa	386	11	characterized	characterize	VBN
cord-015935-r2wd1yfa	386	12	by	by	IN
cord-015935-r2wd1yfa	386	13	cognitive	cognitive	JJ
cord-015935-r2wd1yfa	386	14	delay	delay	NN
cord-015935-r2wd1yfa	386	15	,	,	,
cord-015935-r2wd1yfa	386	16	epilepsy	epilepsy	NN
cord-015935-r2wd1yfa	386	17	,	,	,
cord-015935-r2wd1yfa	386	18	and	and	CC
cord-015935-r2wd1yfa	386	19	neurocutaneous	neurocutaneous	JJ
cord-015935-r2wd1yfa	386	20	growths	growth	NNS
cord-015935-r2wd1yfa	386	21	including	include	VBG
cord-015935-r2wd1yfa	386	22	hamartomas	hamartomas	NNP
cord-015935-r2wd1yfa	386	23	(	(	-LRB-
cord-015935-r2wd1yfa	386	24	i.e.	i.e.	FW
cord-015935-r2wd1yfa	386	25	,	,	,
cord-015935-r2wd1yfa	386	26	tubers	tuber	NNS
cord-015935-r2wd1yfa	386	27	)	)	-RRB-
cord-015935-r2wd1yfa	386	28	within	within	IN
cord-015935-r2wd1yfa	386	29	the	the	DT
cord-015935-r2wd1yfa	386	30	central	central	JJ
cord-015935-r2wd1yfa	386	31	nervous	nervous	JJ
cord-015935-r2wd1yfa	386	32	system	system	NN
cord-015935-r2wd1yfa	386	33	and	and	CC
cord-015935-r2wd1yfa	386	34	other	other	JJ
cord-015935-r2wd1yfa	386	35	organs	organ	NNS
cord-015935-r2wd1yfa	386	36	.	.	.
cord-015935-r2wd1yfa	387	1	Up	up	IN
cord-015935-r2wd1yfa	387	2	to	to	TO
cord-015935-r2wd1yfa	387	3	60	60	CD
cord-015935-r2wd1yfa	387	4	%	%	NN
cord-015935-r2wd1yfa	387	5	of	of	IN
cord-015935-r2wd1yfa	387	6	individuals	individual	NNS
cord-015935-r2wd1yfa	387	7	with	with	IN
cord-015935-r2wd1yfa	387	8	TSC	TSC	NNP
cord-015935-r2wd1yfa	387	9	have	have	VBP
cord-015935-r2wd1yfa	387	10	autism	autism	NN
cord-015935-r2wd1yfa	387	11	.	.	.
cord-015935-r2wd1yfa	388	1	The	the	DT
cord-015935-r2wd1yfa	388	2	first	first	JJ
cord-015935-r2wd1yfa	388	3	suspicion	suspicion	NN
cord-015935-r2wd1yfa	388	4	of	of	IN
cord-015935-r2wd1yfa	388	5	a	a	DT
cord-015935-r2wd1yfa	388	6	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	388	7	abnormality	abnormality	NN
cord-015935-r2wd1yfa	388	8	associated	associate	VBN
cord-015935-r2wd1yfa	388	9	with	with	IN
cord-015935-r2wd1yfa	388	10	TSC	TSC	NNP
cord-015935-r2wd1yfa	388	11	originated	originate	VBD
cord-015935-r2wd1yfa	388	12	from	from	IN
cord-015935-r2wd1yfa	388	13	a	a	DT
cord-015935-r2wd1yfa	388	14	linkage	linkage	NN
cord-015935-r2wd1yfa	388	15	study	study	NN
cord-015935-r2wd1yfa	388	16	of	of	IN
cord-015935-r2wd1yfa	388	17	26	26	CD
cord-015935-r2wd1yfa	388	18	protein	protein	NN
cord-015935-r2wd1yfa	388	19	markers	marker	NNS
cord-015935-r2wd1yfa	388	20	within	within	IN
cord-015935-r2wd1yfa	388	21	19	19	CD
cord-015935-r2wd1yfa	388	22	multigenerational	multigenerational	JJ
cord-015935-r2wd1yfa	388	23	families	family	NNS
cord-015935-r2wd1yfa	388	24	affected	affect	VBN
cord-015935-r2wd1yfa	388	25	with	with	IN
cord-015935-r2wd1yfa	388	26	TSC	TSC	NNP
cord-015935-r2wd1yfa	388	27	(	(	-LRB-
cord-015935-r2wd1yfa	388	28	Fryer	Fryer	NNP
cord-015935-r2wd1yfa	388	29	et	et	NNP
cord-015935-r2wd1yfa	388	30	al	al	NNP
cord-015935-r2wd1yfa	388	31	.	.	NNP
cord-015935-r2wd1yfa	388	32	,	,	,
cord-015935-r2wd1yfa	388	33	1987	1987	CD
cord-015935-r2wd1yfa	388	34	)	)	-RRB-
cord-015935-r2wd1yfa	388	35	.	.	.
cord-015935-r2wd1yfa	389	1	In	in	IN
cord-015935-r2wd1yfa	389	2	eight	eight	CD
cord-015935-r2wd1yfa	389	3	of	of	IN
cord-015935-r2wd1yfa	389	4	the	the	DT
cord-015935-r2wd1yfa	389	5	families	family	NNS
cord-015935-r2wd1yfa	389	6	,	,	,
cord-015935-r2wd1yfa	389	7	ABO	ABO	NNP
cord-015935-r2wd1yfa	389	8	blood	blood	NN
cord-015935-r2wd1yfa	389	9	group	group	NN
cord-015935-r2wd1yfa	389	10	gene	gene	NN
cord-015935-r2wd1yfa	389	11	mapped	map	VBN
cord-015935-r2wd1yfa	389	12	to	to	TO
cord-015935-r2wd1yfa	389	13	chromosome	chromosome	NN
cord-015935-r2wd1yfa	389	14	9q34.3	9q34.3	CD
cord-015935-r2wd1yfa	389	15	.	.	.
cord-015935-r2wd1yfa	390	1	Many	many	JJ
cord-015935-r2wd1yfa	390	2	groups	group	NNS
cord-015935-r2wd1yfa	390	3	corroborated	corroborate	VBD
cord-015935-r2wd1yfa	390	4	these	these	DT
cord-015935-r2wd1yfa	390	5	results	result	NNS
cord-015935-r2wd1yfa	390	6	using	use	VBG
cord-015935-r2wd1yfa	390	7	larger	large	JJR
cord-015935-r2wd1yfa	390	8	numbers	number	NNS
cord-015935-r2wd1yfa	390	9	of	of	IN
cord-015935-r2wd1yfa	390	10	families	family	NNS
cord-015935-r2wd1yfa	390	11	(	(	-LRB-
cord-015935-r2wd1yfa	390	12	Au	Au	NNP
cord-015935-r2wd1yfa	390	13	,	,	,
cord-015935-r2wd1yfa	390	14	Williams	Williams	NNP
cord-015935-r2wd1yfa	390	15	,	,	,
cord-015935-r2wd1yfa	390	16	Gambello	Gambello	NNP
cord-015935-r2wd1yfa	390	17	,	,	,
cord-015935-r2wd1yfa	390	18	&	&	CC
cord-015935-r2wd1yfa	390	19	Northrup	Northrup	NNP
cord-015935-r2wd1yfa	390	20	,	,	,
cord-015935-r2wd1yfa	390	21	2004	2004	CD
cord-015935-r2wd1yfa	390	22	)	)	-RRB-
cord-015935-r2wd1yfa	390	23	.	.	.
cord-015935-r2wd1yfa	391	1	These	these	DT
cord-015935-r2wd1yfa	391	2	linkage	linkage	NN
cord-015935-r2wd1yfa	391	3	studies	study	NNS
cord-015935-r2wd1yfa	391	4	established	establish	VBD
cord-015935-r2wd1yfa	391	5	the	the	DT
cord-015935-r2wd1yfa	391	6	TSC1	TSC1	NNP
cord-015935-r2wd1yfa	391	7	gene	gene	NN
cord-015935-r2wd1yfa	391	8	,	,	,
cord-015935-r2wd1yfa	391	9	later	later	RB
cord-015935-r2wd1yfa	391	10	discovered	discover	VBN
cord-015935-r2wd1yfa	391	11	to	to	TO
cord-015935-r2wd1yfa	391	12	encode	encode	VB
cord-015935-r2wd1yfa	391	13	hamartin	hamartin	NNP
cord-015935-r2wd1yfa	391	14	,	,	,
cord-015935-r2wd1yfa	391	15	a	a	DT
cord-015935-r2wd1yfa	391	16	growth	growth	NN
cord-015935-r2wd1yfa	391	17	suppressor	suppressor	NN
cord-015935-r2wd1yfa	391	18	protein	protein	NN
cord-015935-r2wd1yfa	391	19	.	.	.
cord-015935-r2wd1yfa	392	1	Another	another	DT
cord-015935-r2wd1yfa	392	2	TSC	TSC	NNP
cord-015935-r2wd1yfa	392	3	gene	gene	NN
cord-015935-r2wd1yfa	392	4	site	site	NN
cord-015935-r2wd1yfa	392	5	was	be	VBD
cord-015935-r2wd1yfa	392	6	discovered	discover	VBN
cord-015935-r2wd1yfa	392	7	via	via	IN
cord-015935-r2wd1yfa	392	8	linkage	linkage	NN
cord-015935-r2wd1yfa	392	9	studies	study	NNS
cord-015935-r2wd1yfa	392	10	on	on	IN
cord-015935-r2wd1yfa	392	11	chromosome	chromosome	NN
cord-015935-r2wd1yfa	392	12	16p13.3	16p13.3	CD
cord-015935-r2wd1yfa	392	13	,	,	,
cord-015935-r2wd1yfa	392	14	known	know	VBN
cord-015935-r2wd1yfa	392	15	as	as	IN
cord-015935-r2wd1yfa	392	16	TSC2	TSC2	NNP
cord-015935-r2wd1yfa	392	17	.	.	.
cord-015935-r2wd1yfa	393	1	This	this	DT
cord-015935-r2wd1yfa	393	2	gene	gene	NN
cord-015935-r2wd1yfa	393	3	produces	produce	VBZ
cord-015935-r2wd1yfa	393	4	the	the	DT
cord-015935-r2wd1yfa	393	5	tumor	tumor	NN
cord-015935-r2wd1yfa	393	6	suppressor	suppressor	NN
cord-015935-r2wd1yfa	393	7	protein	protein	NNP
cord-015935-r2wd1yfa	393	8	tuberin	tuberin	NNP
cord-015935-r2wd1yfa	393	9	.	.	.
cord-015935-r2wd1yfa	394	1	Further	further	JJ
cord-015935-r2wd1yfa	394	2	evidence	evidence	NN
cord-015935-r2wd1yfa	394	3	showed	show	VBD
cord-015935-r2wd1yfa	394	4	that	that	IN
cord-015935-r2wd1yfa	394	5	hamartin	hamartin	NN
cord-015935-r2wd1yfa	394	6	works	work	VBZ
cord-015935-r2wd1yfa	394	7	together	together	RB
cord-015935-r2wd1yfa	394	8	with	with	IN
cord-015935-r2wd1yfa	394	9	tuberin	tuberin	NNP
cord-015935-r2wd1yfa	394	10	in	in	IN
cord-015935-r2wd1yfa	394	11	several	several	JJ
cord-015935-r2wd1yfa	394	12	cell	cell	NN
cord-015935-r2wd1yfa	394	13	-	-	HYPH
cord-015935-r2wd1yfa	394	14	signaling	signal	VBG
cord-015935-r2wd1yfa	394	15	pathways	pathway	NNS
cord-015935-r2wd1yfa	394	16	including	include	VBG
cord-015935-r2wd1yfa	394	17	a	a	DT
cord-015935-r2wd1yfa	394	18	growth	growth	NN
cord-015935-r2wd1yfa	394	19	and	and	CC
cord-015935-r2wd1yfa	394	20	translation	translation	NN
cord-015935-r2wd1yfa	394	21	regulatory	regulatory	JJ
cord-015935-r2wd1yfa	394	22	pathway	pathway	NN
cord-015935-r2wd1yfa	394	23	(	(	-LRB-
cord-015935-r2wd1yfa	394	24	P13K	P13K	NNP
cord-015935-r2wd1yfa	394	25	/	/	SYM
cord-015935-r2wd1yfa	394	26	PKB	PKB	NNP
cord-015935-r2wd1yfa	394	27	)	)	-RRB-
cord-015935-r2wd1yfa	394	28	,	,	,
cord-015935-r2wd1yfa	394	29	a	a	DT
cord-015935-r2wd1yfa	394	30	cell	cell	NN
cord-015935-r2wd1yfa	394	31	adhesion	adhesion	NN
cord-015935-r2wd1yfa	394	32	/	/	SYM
cord-015935-r2wd1yfa	394	33	migration	migration	NN
cord-015935-r2wd1yfa	394	34	/	/	SYM
cord-015935-r2wd1yfa	394	35	protein	protein	NN
cord-015935-r2wd1yfa	394	36	transportation	transportation	NN
cord-015935-r2wd1yfa	394	37	pathway	pathway	NN
cord-015935-r2wd1yfa	394	38	[	[	-LRB-
cord-015935-r2wd1yfa	395	1	glycogen	glycogen	NNP
cord-015935-r2wd1yfa	395	2	synthase	synthase	NNP
cord-015935-r2wd1yfa	395	3	kinase	kinase	VBD
cord-015935-r2wd1yfa	395	4	3	3	CD
cord-015935-r2wd1yfa	396	1	(	(	-LRB-
cord-015935-r2wd1yfa	396	2	GSK3)/β	gsk3)/β	JJ
cord-015935-r2wd1yfa	396	3	-	-	HYPH
cord-015935-r2wd1yfa	396	4	catenin	catenin	NNS
cord-015935-r2wd1yfa	396	5	/	/	SYM
cord-015935-r2wd1yfa	396	6	focal	focal	JJ
cord-015935-r2wd1yfa	396	7	adhesion	adhesion	NN
cord-015935-r2wd1yfa	396	8	kinase	kinase	NN
cord-015935-r2wd1yfa	396	9	/	/	SYM
cord-015935-r2wd1yfa	396	10	Ras	Ras	NNP
cord-015935-r2wd1yfa	396	11	-	-	HYPH
cord-015935-r2wd1yfa	396	12	related	relate	VBN
cord-015935-r2wd1yfa	396	13	homolog	homolog	NN
cord-015935-r2wd1yfa	396	14	(	(	-LRB-
cord-015935-r2wd1yfa	396	15	Rho	rho	NN
cord-015935-r2wd1yfa	396	16	)	)	-RRB-
cord-015935-r2wd1yfa	396	17	pathway	pathway	NN
cord-015935-r2wd1yfa	396	18	]	]	-RRB-
cord-015935-r2wd1yfa	396	19	,	,	,
cord-015935-r2wd1yfa	396	20	and	and	CC
cord-015935-r2wd1yfa	396	21	a	a	DT
cord-015935-r2wd1yfa	396	22	cell	cell	NN
cord-015935-r2wd1yfa	396	23	growth	growth	NN
cord-015935-r2wd1yfa	396	24	and	and	CC
cord-015935-r2wd1yfa	396	25	proliferation	proliferation	NN
cord-015935-r2wd1yfa	396	26	pathway	pathway	NN
cord-015935-r2wd1yfa	397	1	[	[	-LRB-
cord-015935-r2wd1yfa	397	2	mitogen	mitogen	NN
cord-015935-r2wd1yfa	397	3	-	-	HYPH
cord-015935-r2wd1yfa	397	4	activated	activate	VBN
cord-015935-r2wd1yfa	397	5	protein	protein	NN
cord-015935-r2wd1yfa	397	6	kinase	kinase	NN
cord-015935-r2wd1yfa	397	7	(	(	-LRB-
cord-015935-r2wd1yfa	397	8	MAPK	MAPK	NNP
cord-015935-r2wd1yfa	397	9	)	)	-RRB-
cord-015935-r2wd1yfa	397	10	]	]	-RRB-
cord-015935-r2wd1yfa	397	11	.	.	.
cord-015935-r2wd1yfa	398	1	The	the	DT
cord-015935-r2wd1yfa	398	2	tuberin	tuberin	NN
cord-015935-r2wd1yfa	398	3	-	-	HYPH
cord-015935-r2wd1yfa	398	4	hamartin	hamartin	NNP
cord-015935-r2wd1yfa	398	5	complex	complex	NN
cord-015935-r2wd1yfa	398	6	affects	affect	VBZ
cord-015935-r2wd1yfa	398	7	mTOR	mTOR	NNP
cord-015935-r2wd1yfa	398	8	kinase	kinase	NN
cord-015935-r2wd1yfa	398	9	activity	activity	NN
cord-015935-r2wd1yfa	398	10	(	(	-LRB-
cord-015935-r2wd1yfa	398	11	Au	Au	NNP
cord-015935-r2wd1yfa	398	12	et	et	FW
cord-015935-r2wd1yfa	398	13	al	al	NNP
cord-015935-r2wd1yfa	398	14	.	.	NNP
cord-015935-r2wd1yfa	398	15	,	,	,
cord-015935-r2wd1yfa	398	16	2004	2004	CD
cord-015935-r2wd1yfa	398	17	)	)	-RRB-
cord-015935-r2wd1yfa	398	18	,	,	,
cord-015935-r2wd1yfa	398	19	promoting	promote	VBG
cord-015935-r2wd1yfa	398	20	tumor	tumor	NN
cord-015935-r2wd1yfa	398	21	growth	growth	NN
cord-015935-r2wd1yfa	398	22	.	.	.
cord-015935-r2wd1yfa	399	1	This	this	DT
cord-015935-r2wd1yfa	399	2	discovery	discovery	NN
cord-015935-r2wd1yfa	399	3	has	have	VBZ
cord-015935-r2wd1yfa	399	4	led	lead	VBN
cord-015935-r2wd1yfa	399	5	to	to	IN
cord-015935-r2wd1yfa	399	6	the	the	DT
cord-015935-r2wd1yfa	399	7	study	study	NN
cord-015935-r2wd1yfa	399	8	of	of	IN
cord-015935-r2wd1yfa	399	9	rapamycin	rapamycin	NNP
cord-015935-r2wd1yfa	399	10	,	,	,
cord-015935-r2wd1yfa	399	11	a	a	DT
cord-015935-r2wd1yfa	399	12	drug	drug	NN
cord-015935-r2wd1yfa	399	13	used	use	VBN
cord-015935-r2wd1yfa	399	14	in	in	IN
cord-015935-r2wd1yfa	399	15	organ	organ	NN
cord-015935-r2wd1yfa	399	16	transplant	transplant	NN
cord-015935-r2wd1yfa	399	17	and	and	CC
cord-015935-r2wd1yfa	399	18	cancer	cancer	NN
cord-015935-r2wd1yfa	399	19	treatment	treatment	NN
cord-015935-r2wd1yfa	399	20	,	,	,
cord-015935-r2wd1yfa	399	21	as	as	IN
cord-015935-r2wd1yfa	399	22	a	a	DT
cord-015935-r2wd1yfa	399	23	therapy	therapy	NN
cord-015935-r2wd1yfa	399	24	for	for	IN
cord-015935-r2wd1yfa	399	25	suppressing	suppress	VBG
cord-015935-r2wd1yfa	399	26	growth	growth	NN
cord-015935-r2wd1yfa	399	27	of	of	IN
cord-015935-r2wd1yfa	399	28	tumors	tumor	NNS
cord-015935-r2wd1yfa	399	29	in	in	IN
cord-015935-r2wd1yfa	399	30	TSC	TSC	NNP
cord-015935-r2wd1yfa	399	31	(	(	-LRB-
cord-015935-r2wd1yfa	399	32	Kenerson	Kenerson	NNP
cord-015935-r2wd1yfa	399	33	,	,	,
cord-015935-r2wd1yfa	399	34	Aicher	Aicher	NNP
cord-015935-r2wd1yfa	399	35	,	,	,
cord-015935-r2wd1yfa	399	36	True	True	NNP
cord-015935-r2wd1yfa	399	37	,	,	,
cord-015935-r2wd1yfa	399	38	&	&	CC
cord-015935-r2wd1yfa	399	39	Yeung	Yeung	NNP
cord-015935-r2wd1yfa	399	40	,	,	,
cord-015935-r2wd1yfa	399	41	2002	2002	CD
cord-015935-r2wd1yfa	399	42	)	)	-RRB-
cord-015935-r2wd1yfa	399	43	.	.	.
cord-015935-r2wd1yfa	400	1	Other	other	JJ
cord-015935-r2wd1yfa	400	2	growth	growth	NN
cord-015935-r2wd1yfa	400	3	-	-	HYPH
cord-015935-r2wd1yfa	400	4	promoting	promote	VBG
cord-015935-r2wd1yfa	400	5	genes	gene	NNS
cord-015935-r2wd1yfa	400	6	such	such	JJ
cord-015935-r2wd1yfa	400	7	as	as	IN
cord-015935-r2wd1yfa	400	8	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	400	9	have	have	VBP
cord-015935-r2wd1yfa	400	10	been	be	VBN
cord-015935-r2wd1yfa	400	11	linked	link	VBN
cord-015935-r2wd1yfa	400	12	to	to	IN
cord-015935-r2wd1yfa	400	13	the	the	DT
cord-015935-r2wd1yfa	400	14	tuberin	tuberin	NNP
cord-015935-r2wd1yfa	400	15	-	-	HYPH
cord-015935-r2wd1yfa	400	16	hamartin	hamartin	NNP
cord-015935-r2wd1yfa	400	17	gene	gene	NN
cord-015935-r2wd1yfa	400	18	complex	complex	NN
cord-015935-r2wd1yfa	400	19	as	as	IN
cord-015935-r2wd1yfa	400	20	contributors	contributor	NNS
cord-015935-r2wd1yfa	400	21	to	to	IN
cord-015935-r2wd1yfa	400	22	the	the	DT
cord-015935-r2wd1yfa	400	23	general	general	JJ
cord-015935-r2wd1yfa	400	24	overgrowth	overgrowth	NN
cord-015935-r2wd1yfa	400	25	in	in	IN
cord-015935-r2wd1yfa	400	26	TSC	TSC	NNP
cord-015935-r2wd1yfa	400	27	.	.	.
cord-015935-r2wd1yfa	401	1	As	as	IN
cord-015935-r2wd1yfa	401	2	previously	previously	RB
cord-015935-r2wd1yfa	401	3	discussed	discuss	VBN
cord-015935-r2wd1yfa	401	4	,	,	,
cord-015935-r2wd1yfa	401	5	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	401	6	is	be	VBZ
cord-015935-r2wd1yfa	401	7	a	a	DT
cord-015935-r2wd1yfa	401	8	gene	gene	NN
cord-015935-r2wd1yfa	401	9	of	of	IN
cord-015935-r2wd1yfa	401	10	interest	interest	NN
cord-015935-r2wd1yfa	401	11	in	in	IN
cord-015935-r2wd1yfa	401	12	autism	autism	NN
cord-015935-r2wd1yfa	401	13	.	.	.
cord-015935-r2wd1yfa	402	1	Buxbaum	Buxbaum	NNP
cord-015935-r2wd1yfa	402	2	et	et	NNP
cord-015935-r2wd1yfa	402	3	al	al	NNP
cord-015935-r2wd1yfa	402	4	.	.	.
cord-015935-r2wd1yfa	403	1	(	(	-LRB-
cord-015935-r2wd1yfa	403	2	2007	2007	CD
cord-015935-r2wd1yfa	403	3	)	)	-RRB-
cord-015935-r2wd1yfa	403	4	,	,	,
cord-015935-r2wd1yfa	403	5	together	together	RB
cord-015935-r2wd1yfa	403	6	with	with	IN
cord-015935-r2wd1yfa	403	7	the	the	DT
cord-015935-r2wd1yfa	403	8	Seaver	Seaver	NNP
cord-015935-r2wd1yfa	403	9	Autism	Autism	NNP
cord-015935-r2wd1yfa	403	10	Research	Research	NNP
cord-015935-r2wd1yfa	403	11	Center	Center	NNP
cord-015935-r2wd1yfa	403	12	(	(	-LRB-
cord-015935-r2wd1yfa	403	13	SARS	SARS	NNP
cord-015935-r2wd1yfa	403	14	)	)	-RRB-
cord-015935-r2wd1yfa	403	15	,	,	,
cord-015935-r2wd1yfa	403	16	reported	report	VBD
cord-015935-r2wd1yfa	403	17	a	a	DT
cord-015935-r2wd1yfa	403	18	two	two	CD
cord-015935-r2wd1yfa	403	19	-	-	HYPH
cord-015935-r2wd1yfa	403	20	point	point	NN
cord-015935-r2wd1yfa	403	21	dominant	dominant	JJ
cord-015935-r2wd1yfa	403	22	LOD	lod	NN
cord-015935-r2wd1yfa	403	23	score	score	NN
cord-015935-r2wd1yfa	403	24	of	of	IN
cord-015935-r2wd1yfa	403	25	2.25	2.25	CD
cord-015935-r2wd1yfa	403	26	on	on	IN
cord-015935-r2wd1yfa	403	27	chromosome	chromosome	NN
cord-015935-r2wd1yfa	403	28	2q	2q	CD
cord-015935-r2wd1yfa	403	29	in	in	IN
cord-015935-r2wd1yfa	403	30	35	35	CD
cord-015935-r2wd1yfa	403	31	affected	affected	JJ
cord-015935-r2wd1yfa	403	32	sibling	sibling	NN
cord-015935-r2wd1yfa	403	33	pairs	pair	NNS
cord-015935-r2wd1yfa	403	34	.	.	.
cord-015935-r2wd1yfa	404	1	In	in	IN
cord-015935-r2wd1yfa	404	2	a	a	DT
cord-015935-r2wd1yfa	404	3	second	second	JJ
cord-015935-r2wd1yfa	404	4	-	-	HYPH
cord-015935-r2wd1yfa	404	5	stage	stage	NN
cord-015935-r2wd1yfa	404	6	screening	screening	NN
cord-015935-r2wd1yfa	404	7	which	which	WDT
cord-015935-r2wd1yfa	404	8	employed	employ	VBD
cord-015935-r2wd1yfa	404	9	60	60	CD
cord-015935-r2wd1yfa	404	10	families	family	NNS
cord-015935-r2wd1yfa	404	11	with	with	IN
cord-015935-r2wd1yfa	404	12	autism	autism	NN
cord-015935-r2wd1yfa	404	13	probands	proband	NNS
cord-015935-r2wd1yfa	404	14	,	,	,
cord-015935-r2wd1yfa	404	15	the	the	DT
cord-015935-r2wd1yfa	404	16	strongest	strong	JJS
cord-015935-r2wd1yfa	404	17	linkage	linkage	NN
cord-015935-r2wd1yfa	404	18	was	be	VBD
cord-015935-r2wd1yfa	404	19	at	at	IN
cord-015935-r2wd1yfa	404	20	this	this	DT
cord-015935-r2wd1yfa	404	21	same	same	JJ
cord-015935-r2wd1yfa	404	22	location	location	NN
cord-015935-r2wd1yfa	404	23	.	.	.
cord-015935-r2wd1yfa	405	1	The	the	DT
cord-015935-r2wd1yfa	405	2	IMGSAC	IMGSAC	NNP
cord-015935-r2wd1yfa	405	3	study	study	NN
cord-015935-r2wd1yfa	405	4	showed	show	VBD
cord-015935-r2wd1yfa	405	5	a	a	DT
cord-015935-r2wd1yfa	405	6	strong	strong	JJ
cord-015935-r2wd1yfa	405	7	linkage	linkage	NN
cord-015935-r2wd1yfa	405	8	to	to	IN
cord-015935-r2wd1yfa	405	9	7q	7q	CD
cord-015935-r2wd1yfa	405	10	as	as	IN
cord-015935-r2wd1yfa	405	11	described	describe	VBN
cord-015935-r2wd1yfa	405	12	above	above	RB
cord-015935-r2wd1yfa	405	13	,	,	,
cord-015935-r2wd1yfa	405	14	but	but	CC
cord-015935-r2wd1yfa	405	15	also	also	RB
cord-015935-r2wd1yfa	405	16	found	find	VBD
cord-015935-r2wd1yfa	405	17	linkage	linkage	NN
cord-015935-r2wd1yfa	405	18	to	to	IN
cord-015935-r2wd1yfa	405	19	2q	2q	CD
cord-015935-r2wd1yfa	405	20	(	(	-LRB-
cord-015935-r2wd1yfa	405	21	IMGSAC	IMGSAC	NNP
cord-015935-r2wd1yfa	405	22	,	,	,
cord-015935-r2wd1yfa	405	23	1998	1998	CD
cord-015935-r2wd1yfa	405	24	)	)	-RRB-
cord-015935-r2wd1yfa	405	25	,	,	,
cord-015935-r2wd1yfa	405	26	with	with	IN
cord-015935-r2wd1yfa	405	27	a	a	DT
cord-015935-r2wd1yfa	405	28	more	more	RBR
cord-015935-r2wd1yfa	405	29	recent	recent	JJ
cord-015935-r2wd1yfa	405	30	study	study	NN
cord-015935-r2wd1yfa	405	31	also	also	RB
cord-015935-r2wd1yfa	405	32	providing	provide	VBG
cord-015935-r2wd1yfa	405	33	evidence	evidence	NN
cord-015935-r2wd1yfa	405	34	for	for	IN
cord-015935-r2wd1yfa	405	35	linkage	linkage	NN
cord-015935-r2wd1yfa	405	36	to	to	IN
cord-015935-r2wd1yfa	405	37	2q	2q	CD
cord-015935-r2wd1yfa	405	38	(	(	-LRB-
cord-015935-r2wd1yfa	405	39	IMGSAC	IMGSAC	NNP
cord-015935-r2wd1yfa	405	40	,	,	,
cord-015935-r2wd1yfa	405	41	2001b	2001b	CD
cord-015935-r2wd1yfa	405	42	)	)	-RRB-
cord-015935-r2wd1yfa	405	43	.	.	.
cord-015935-r2wd1yfa	406	1	Early	early	JJ
cord-015935-r2wd1yfa	406	2	recognition	recognition	NN
cord-015935-r2wd1yfa	406	3	of	of	IN
cord-015935-r2wd1yfa	406	4	the	the	DT
cord-015935-r2wd1yfa	406	5	need	need	NN
cord-015935-r2wd1yfa	406	6	for	for	IN
cord-015935-r2wd1yfa	406	7	large	large	JJ
cord-015935-r2wd1yfa	406	8	patient	patient	JJ
cord-015935-r2wd1yfa	406	9	cohorts	cohort	NNS
cord-015935-r2wd1yfa	406	10	and	and	CC
cord-015935-r2wd1yfa	406	11	substantial	substantial	JJ
cord-015935-r2wd1yfa	406	12	genetic	genetic	JJ
cord-015935-r2wd1yfa	406	13	heterogeneity	heterogeneity	NN
cord-015935-r2wd1yfa	406	14	led	lead	VBD
cord-015935-r2wd1yfa	406	15	to	to	IN
cord-015935-r2wd1yfa	406	16	the	the	DT
cord-015935-r2wd1yfa	406	17	establishment	establishment	NN
cord-015935-r2wd1yfa	406	18	of	of	IN
cord-015935-r2wd1yfa	406	19	the	the	DT
cord-015935-r2wd1yfa	406	20	autism	autism	NN
cord-015935-r2wd1yfa	406	21	genetic	genetic	JJ
cord-015935-r2wd1yfa	406	22	resource	resource	NN
cord-015935-r2wd1yfa	406	23	exchange	exchange	NN
cord-015935-r2wd1yfa	406	24	(	(	-LRB-
cord-015935-r2wd1yfa	406	25	AGRE	AGRE	NNP
cord-015935-r2wd1yfa	406	26	)	)	-RRB-
cord-015935-r2wd1yfa	406	27	composed	compose	VBN
cord-015935-r2wd1yfa	406	28	of	of	IN
cord-015935-r2wd1yfa	406	29	over	over	IN
cord-015935-r2wd1yfa	406	30	500	500	CD
cord-015935-r2wd1yfa	406	31	families	family	NNS
cord-015935-r2wd1yfa	406	32	.	.	.
cord-015935-r2wd1yfa	407	1	AGRE	AGRE	NNP
cord-015935-r2wd1yfa	407	2	is	be	VBZ
cord-015935-r2wd1yfa	407	3	a	a	DT
cord-015935-r2wd1yfa	407	4	publically	publically	RB
cord-015935-r2wd1yfa	407	5	available	available	JJ
cord-015935-r2wd1yfa	407	6	resource	resource	NN
cord-015935-r2wd1yfa	407	7	of	of	IN
cord-015935-r2wd1yfa	407	8	phenotypic	phenotypic	JJ
cord-015935-r2wd1yfa	407	9	data	datum	NNS
cord-015935-r2wd1yfa	407	10	and	and	CC
cord-015935-r2wd1yfa	407	11	biomaterials	biomaterial	NNS
cord-015935-r2wd1yfa	407	12	.	.	.
cord-015935-r2wd1yfa	408	1	Genomic	genomic	JJ
cord-015935-r2wd1yfa	408	2	scan	scan	JJ
cord-015935-r2wd1yfa	408	3	linkage	linkage	NN
cord-015935-r2wd1yfa	408	4	analysis	analysis	NN
cord-015935-r2wd1yfa	408	5	was	be	VBD
cord-015935-r2wd1yfa	408	6	performed	perform	VBN
cord-015935-r2wd1yfa	408	7	on	on	IN
cord-015935-r2wd1yfa	408	8	109	109	CD
cord-015935-r2wd1yfa	408	9	autistic	autistic	JJ
cord-015935-r2wd1yfa	408	10	sibling	sibling	NN
cord-015935-r2wd1yfa	408	11	pairs	pair	NNS
cord-015935-r2wd1yfa	408	12	from	from	IN
cord-015935-r2wd1yfa	408	13	91	91	CD
cord-015935-r2wd1yfa	408	14	AGRE	AGRE	NNP
cord-015935-r2wd1yfa	408	15	families	family	NNS
cord-015935-r2wd1yfa	408	16	together	together	RB
cord-015935-r2wd1yfa	408	17	with	with	IN
cord-015935-r2wd1yfa	408	18	analysis	analysis	NN
cord-015935-r2wd1yfa	408	19	of	of	IN
cord-015935-r2wd1yfa	408	20	those	those	DT
cord-015935-r2wd1yfa	408	21	pairs	pair	NNS
cord-015935-r2wd1yfa	408	22	from	from	IN
cord-015935-r2wd1yfa	408	23	an	an	DT
cord-015935-r2wd1yfa	408	24	independent	independent	JJ
cord-015935-r2wd1yfa	408	25	sample	sample	NN
cord-015935-r2wd1yfa	408	26	of	of	IN
cord-015935-r2wd1yfa	408	27	345	345	CD
cord-015935-r2wd1yfa	408	28	families	family	NNS
cord-015935-r2wd1yfa	408	29	from	from	IN
cord-015935-r2wd1yfa	408	30	the	the	DT
cord-015935-r2wd1yfa	408	31	same	same	JJ
cord-015935-r2wd1yfa	408	32	AGRE	AGRE	NNP
cord-015935-r2wd1yfa	408	33	cohort	cohort	NN
cord-015935-r2wd1yfa	408	34	(	(	-LRB-
cord-015935-r2wd1yfa	408	35	Cantor	Cantor	NNP
cord-015935-r2wd1yfa	408	36	et	et	NNP
cord-015935-r2wd1yfa	408	37	al	al	NNP
cord-015935-r2wd1yfa	408	38	.	.	NNP
cord-015935-r2wd1yfa	408	39	,	,	,
cord-015935-r2wd1yfa	408	40	2005	2005	CD
cord-015935-r2wd1yfa	408	41	)	)	-RRB-
cord-015935-r2wd1yfa	408	42	.	.	.
cord-015935-r2wd1yfa	409	1	When	when	WRB
cord-015935-r2wd1yfa	409	2	families	family	NNS
cord-015935-r2wd1yfa	409	3	with	with	IN
cord-015935-r2wd1yfa	409	4	autism	autism	NN
cord-015935-r2wd1yfa	409	5	were	be	VBD
cord-015935-r2wd1yfa	409	6	stratified	stratify	VBN
cord-015935-r2wd1yfa	409	7	into	into	IN
cord-015935-r2wd1yfa	409	8	only	only	RB
cord-015935-r2wd1yfa	409	9	those	those	DT
cord-015935-r2wd1yfa	409	10	with	with	IN
cord-015935-r2wd1yfa	409	11	affected	affected	JJ
cord-015935-r2wd1yfa	409	12	males	male	NNS
cord-015935-r2wd1yfa	409	13	,	,	,
cord-015935-r2wd1yfa	409	14	there	there	EX
cord-015935-r2wd1yfa	409	15	was	be	VBD
cord-015935-r2wd1yfa	409	16	significant	significant	JJ
cord-015935-r2wd1yfa	409	17	linkage	linkage	NN
cord-015935-r2wd1yfa	409	18	at	at	IN
cord-015935-r2wd1yfa	409	19	17q11	17q11	CD
cord-015935-r2wd1yfa	409	20	-	-	SYM
cord-015935-r2wd1yfa	409	21	21	21	CD
cord-015935-r2wd1yfa	409	22	in	in	IN
cord-015935-r2wd1yfa	409	23	both	both	DT
cord-015935-r2wd1yfa	409	24	samples	sample	NNS
cord-015935-r2wd1yfa	409	25	.	.	.
cord-015935-r2wd1yfa	410	1	The	the	DT
cord-015935-r2wd1yfa	410	2	LOD	lod	NN
cord-015935-r2wd1yfa	410	3	score	score	NN
cord-015935-r2wd1yfa	410	4	for	for	IN
cord-015935-r2wd1yfa	410	5	this	this	DT
cord-015935-r2wd1yfa	410	6	replicated	replicate	VBN
cord-015935-r2wd1yfa	410	7	work	work	NN
cord-015935-r2wd1yfa	410	8	was	be	VBD
cord-015935-r2wd1yfa	410	9	at	at	IN
cord-015935-r2wd1yfa	410	10	genome	genome	NN
cord-015935-r2wd1yfa	410	11	-	-	HYPH
cord-015935-r2wd1yfa	410	12	wide	wide	JJ
cord-015935-r2wd1yfa	410	13	level	level	NN
cord-015935-r2wd1yfa	410	14	of	of	IN
cord-015935-r2wd1yfa	410	15	significance	significance	NN
cord-015935-r2wd1yfa	411	1	(	(	-LRB-
cord-015935-r2wd1yfa	411	2	LOD	lod	NN
cord-015935-r2wd1yfa	411	3	score	score	NN
cord-015935-r2wd1yfa	411	4	>	>	XX
cord-015935-r2wd1yfa	411	5	1.4	1.4	CD
cord-015935-r2wd1yfa	411	6	)	)	-RRB-
cord-015935-r2wd1yfa	411	7	.	.	.
cord-015935-r2wd1yfa	412	1	One	one	CD
cord-015935-r2wd1yfa	412	2	positional	positional	JJ
cord-015935-r2wd1yfa	412	3	candidate	candidate	NN
cord-015935-r2wd1yfa	412	4	gene	gene	NN
cord-015935-r2wd1yfa	412	5	close	close	RB
cord-015935-r2wd1yfa	412	6	to	to	IN
cord-015935-r2wd1yfa	412	7	this	this	DT
cord-015935-r2wd1yfa	412	8	region	region	NN
cord-015935-r2wd1yfa	412	9	is	be	VBZ
cord-015935-r2wd1yfa	412	10	the	the	DT
cord-015935-r2wd1yfa	412	11	serotonin	serotonin	NN
cord-015935-r2wd1yfa	412	12	transporter	transporter	NN
cord-015935-r2wd1yfa	412	13	gene	gene	NN
cord-015935-r2wd1yfa	412	14	(	(	-LRB-
cord-015935-r2wd1yfa	412	15	SLC6A4	SLC6A4	NNP
cord-015935-r2wd1yfa	412	16	)	)	-RRB-
cord-015935-r2wd1yfa	412	17	which	which	WDT
cord-015935-r2wd1yfa	412	18	codes	code	VBZ
cord-015935-r2wd1yfa	412	19	for	for	IN
cord-015935-r2wd1yfa	412	20	a	a	DT
cord-015935-r2wd1yfa	412	21	protein	protein	NN
cord-015935-r2wd1yfa	412	22	controlling	control	VBG
cord-015935-r2wd1yfa	412	23	the	the	DT
cord-015935-r2wd1yfa	412	24	reuptake	reuptake	NN
cord-015935-r2wd1yfa	412	25	of	of	IN
cord-015935-r2wd1yfa	412	26	serotonin	serotonin	NN
cord-015935-r2wd1yfa	412	27	in	in	IN
cord-015935-r2wd1yfa	412	28	the	the	DT
cord-015935-r2wd1yfa	412	29	synapse	synapse	NN
cord-015935-r2wd1yfa	412	30	.	.	.
cord-015935-r2wd1yfa	413	1	This	this	DT
cord-015935-r2wd1yfa	413	2	was	be	VBD
cord-015935-r2wd1yfa	413	3	exciting	exciting	JJ
cord-015935-r2wd1yfa	413	4	as	as	IN
cord-015935-r2wd1yfa	413	5	elevated	elevated	JJ
cord-015935-r2wd1yfa	413	6	levels	level	NNS
cord-015935-r2wd1yfa	413	7	of	of	IN
cord-015935-r2wd1yfa	413	8	serotonin	serotonin	NN
cord-015935-r2wd1yfa	413	9	have	have	VBP
cord-015935-r2wd1yfa	413	10	been	be	VBN
cord-015935-r2wd1yfa	413	11	determined	determine	VBN
cord-015935-r2wd1yfa	413	12	in	in	IN
cord-015935-r2wd1yfa	413	13	25	25	CD
cord-015935-r2wd1yfa	413	14	-	-	SYM
cord-015935-r2wd1yfa	413	15	30	30	CD
cord-015935-r2wd1yfa	413	16	%	%	NN
cord-015935-r2wd1yfa	413	17	of	of	IN
cord-015935-r2wd1yfa	413	18	cases	case	NNS
cord-015935-r2wd1yfa	413	19	of	of	IN
cord-015935-r2wd1yfa	413	20	autism	autism	NN
cord-015935-r2wd1yfa	414	1	(	(	-LRB-
cord-015935-r2wd1yfa	414	2	Cook	Cook	NNP
cord-015935-r2wd1yfa	414	3	et	et	NNP
cord-015935-r2wd1yfa	414	4	al	al	NNP
cord-015935-r2wd1yfa	414	5	.	.	NNP
cord-015935-r2wd1yfa	414	6	,	,	,
cord-015935-r2wd1yfa	414	7	1990	1990	CD
cord-015935-r2wd1yfa	414	8	)	)	-RRB-
cord-015935-r2wd1yfa	414	9	.	.	.
cord-015935-r2wd1yfa	415	1	Indeed	indeed	RB
cord-015935-r2wd1yfa	415	2	,	,	,
cord-015935-r2wd1yfa	415	3	relationship	relationship	NN
cord-015935-r2wd1yfa	415	4	between	between	IN
cord-015935-r2wd1yfa	415	5	the	the	DT
cord-015935-r2wd1yfa	415	6	SLC6A4	SLC6A4	NNP
cord-015935-r2wd1yfa	415	7	site	site	NN
cord-015935-r2wd1yfa	415	8	and	and	CC
cord-015935-r2wd1yfa	415	9	a	a	DT
cord-015935-r2wd1yfa	415	10	repeat	repeat	NN
cord-015935-r2wd1yfa	415	11	polymorphic	polymorphic	JJ
cord-015935-r2wd1yfa	415	12	region	region	NN
cord-015935-r2wd1yfa	415	13	in	in	IN
cord-015935-r2wd1yfa	415	14	its	-PRON-	PRP$
cord-015935-r2wd1yfa	415	15	promoter	promoter	NN
cord-015935-r2wd1yfa	415	16	region	region	NN
cord-015935-r2wd1yfa	415	17	(	(	-LRB-
cord-015935-r2wd1yfa	415	18	5HTTLPR	5HTTLPR	NNP
cord-015935-r2wd1yfa	415	19	)	)	-RRB-
cord-015935-r2wd1yfa	415	20	recently	recently	RB
cord-015935-r2wd1yfa	415	21	has	have	VBZ
cord-015935-r2wd1yfa	415	22	been	be	VBN
cord-015935-r2wd1yfa	415	23	independently	independently	RB
cord-015935-r2wd1yfa	415	24	investigated	investigate	VBN
cord-015935-r2wd1yfa	415	25	(	(	-LRB-
cord-015935-r2wd1yfa	415	26	Losh	Losh	NNP
cord-015935-r2wd1yfa	415	27	et	et	NNP
cord-015935-r2wd1yfa	415	28	al	al	NNP
cord-015935-r2wd1yfa	415	29	.	.	NNP
cord-015935-r2wd1yfa	415	30	,	,	,
cord-015935-r2wd1yfa	415	31	2008	2008	CD
cord-015935-r2wd1yfa	415	32	)	)	-RRB-
cord-015935-r2wd1yfa	415	33	.	.	.
cord-015935-r2wd1yfa	416	1	The	the	DT
cord-015935-r2wd1yfa	416	2	chromosome	chromosome	NN
cord-015935-r2wd1yfa	416	3	17q	17q	CD
cord-015935-r2wd1yfa	416	4	locus	locus	NN
cord-015935-r2wd1yfa	416	5	,	,	,
cord-015935-r2wd1yfa	416	6	however	however	RB
cord-015935-r2wd1yfa	416	7	,	,	,
cord-015935-r2wd1yfa	416	8	has	have	VBZ
cord-015935-r2wd1yfa	416	9	not	not	RB
cord-015935-r2wd1yfa	416	10	been	be	VBN
cord-015935-r2wd1yfa	416	11	uniformly	uniformly	RB
cord-015935-r2wd1yfa	416	12	observed	observe	VBN
cord-015935-r2wd1yfa	416	13	in	in	IN
cord-015935-r2wd1yfa	416	14	subsequent	subsequent	JJ
cord-015935-r2wd1yfa	416	15	,	,	,
cord-015935-r2wd1yfa	416	16	large	large	JJ
cord-015935-r2wd1yfa	416	17	-	-	HYPH
cord-015935-r2wd1yfa	416	18	scale	scale	NN
cord-015935-r2wd1yfa	416	19	studies	study	NNS
cord-015935-r2wd1yfa	416	20	(	(	-LRB-
cord-015935-r2wd1yfa	416	21	Schellenberg	Schellenberg	NNP
cord-015935-r2wd1yfa	416	22	et	et	FW
cord-015935-r2wd1yfa	416	23	al	al	NNP
cord-015935-r2wd1yfa	416	24	.	.	NNP
cord-015935-r2wd1yfa	416	25	,	,	,
cord-015935-r2wd1yfa	416	26	2006	2006	CD
cord-015935-r2wd1yfa	416	27	)	)	-RRB-
cord-015935-r2wd1yfa	416	28	which	which	WDT
cord-015935-r2wd1yfa	416	29	may	may	MD
cord-015935-r2wd1yfa	416	30	be	be	VB
cord-015935-r2wd1yfa	416	31	due	due	JJ
cord-015935-r2wd1yfa	416	32	to	to	IN
cord-015935-r2wd1yfa	416	33	phenotypic	phenotypic	JJ
cord-015935-r2wd1yfa	416	34	heterogeneity	heterogeneity	NN
cord-015935-r2wd1yfa	416	35	.	.	.
cord-015935-r2wd1yfa	417	1	A	a	DT
cord-015935-r2wd1yfa	417	2	very	very	RB
cord-015935-r2wd1yfa	417	3	recent	recent	JJ
cord-015935-r2wd1yfa	417	4	genome	genome	NN
cord-015935-r2wd1yfa	417	5	-	-	HYPH
cord-015935-r2wd1yfa	417	6	wide	wide	JJ
cord-015935-r2wd1yfa	417	7	linkage	linkage	NN
cord-015935-r2wd1yfa	417	8	mapping	mapping	NN
cord-015935-r2wd1yfa	417	9	study	study	NN
cord-015935-r2wd1yfa	417	10	in	in	IN
cord-015935-r2wd1yfa	417	11	a	a	DT
cord-015935-r2wd1yfa	417	12	sample	sample	NN
cord-015935-r2wd1yfa	417	13	of	of	IN
cord-015935-r2wd1yfa	417	14	1,031	1,031	CD
cord-015935-r2wd1yfa	417	15	multiplex	multiplex	JJ
cord-015935-r2wd1yfa	417	16	autism	autism	NN
cord-015935-r2wd1yfa	417	17	families	family	NNS
cord-015935-r2wd1yfa	417	18	(	(	-LRB-
cord-015935-r2wd1yfa	417	19	Weiss	Weiss	NNP
cord-015935-r2wd1yfa	417	20	,	,	,
cord-015935-r2wd1yfa	417	21	Arking	Arking	NNP
cord-015935-r2wd1yfa	417	22	,	,	,
cord-015935-r2wd1yfa	417	23	Daly	Daly	NNP
cord-015935-r2wd1yfa	417	24	,	,	,
cord-015935-r2wd1yfa	417	25	&	&	CC
cord-015935-r2wd1yfa	417	26	Chakravarti	Chakravarti	NNP
cord-015935-r2wd1yfa	417	27	,	,	,
cord-015935-r2wd1yfa	417	28	2009	2009	CD
cord-015935-r2wd1yfa	417	29	)	)	-RRB-
cord-015935-r2wd1yfa	417	30	identified	identify	VBD
cord-015935-r2wd1yfa	417	31	significant	significant	JJ
cord-015935-r2wd1yfa	417	32	linkage	linkage	NN
cord-015935-r2wd1yfa	417	33	on	on	IN
cord-015935-r2wd1yfa	417	34	chromosome	chromosome	NN
cord-015935-r2wd1yfa	417	35	20p13	20p13	CD
cord-015935-r2wd1yfa	417	36	and	and	CC
cord-015935-r2wd1yfa	417	37	suggestive	suggestive	JJ
cord-015935-r2wd1yfa	417	38	linkage	linkage	NN
cord-015935-r2wd1yfa	417	39	on	on	IN
cord-015935-r2wd1yfa	417	40	chromosome	chromosome	NN
cord-015935-r2wd1yfa	417	41	6q27	6q27	CD
cord-015935-r2wd1yfa	417	42	.	.	.
cord-015935-r2wd1yfa	418	1	In	in	IN
cord-015935-r2wd1yfa	418	2	this	this	DT
cord-015935-r2wd1yfa	418	3	study	study	NN
cord-015935-r2wd1yfa	418	4	,	,	,
cord-015935-r2wd1yfa	418	5	no	no	DT
cord-015935-r2wd1yfa	418	6	associations	association	NNS
cord-015935-r2wd1yfa	418	7	meeting	meeting	NN
cord-015935-r2wd1yfa	418	8	criteria	criterion	NNS
cord-015935-r2wd1yfa	418	9	for	for	IN
cord-015935-r2wd1yfa	418	10	genome	genome	NN
cord-015935-r2wd1yfa	418	11	-	-	HYPH
cord-015935-r2wd1yfa	418	12	wide	wide	JJ
cord-015935-r2wd1yfa	418	13	significance	significance	NN
cord-015935-r2wd1yfa	418	14	were	be	VBD
cord-015935-r2wd1yfa	418	15	found	find	VBN
cord-015935-r2wd1yfa	418	16	,	,	,
cord-015935-r2wd1yfa	418	17	suggesting	suggest	VBG
cord-015935-r2wd1yfa	418	18	there	there	EX
cord-015935-r2wd1yfa	418	19	are	be	VBP
cord-015935-r2wd1yfa	418	20	not	not	RB
cord-015935-r2wd1yfa	418	21	many	many	JJ
cord-015935-r2wd1yfa	418	22	common	common	JJ
cord-015935-r2wd1yfa	418	23	loci	locus	NNS
cord-015935-r2wd1yfa	418	24	of	of	IN
cord-015935-r2wd1yfa	418	25	moderate	moderate	JJ
cord-015935-r2wd1yfa	418	26	to	to	IN
cord-015935-r2wd1yfa	418	27	large	large	JJ
cord-015935-r2wd1yfa	418	28	effect	effect	NN
cord-015935-r2wd1yfa	418	29	size	size	NN
cord-015935-r2wd1yfa	418	30	.	.	.
cord-015935-r2wd1yfa	419	1	However	however	RB
cord-015935-r2wd1yfa	419	2	,	,	,
cord-015935-r2wd1yfa	419	3	replication	replication	NN
cord-015935-r2wd1yfa	419	4	data	datum	NNS
cord-015935-r2wd1yfa	419	5	revealed	reveal	VBD
cord-015935-r2wd1yfa	419	6	a	a	DT
cord-015935-r2wd1yfa	419	7	novel	novel	JJ
cord-015935-r2wd1yfa	419	8	SNP	SNP	NNP
cord-015935-r2wd1yfa	419	9	locus	locus	NN
cord-015935-r2wd1yfa	419	10	on	on	IN
cord-015935-r2wd1yfa	419	11	chromosome	chromosome	NN
cord-015935-r2wd1yfa	419	12	5p15	5p15	CD
cord-015935-r2wd1yfa	419	13	.	.	.
cord-015935-r2wd1yfa	420	1	This	this	DT
cord-015935-r2wd1yfa	420	2	region	region	NN
cord-015935-r2wd1yfa	420	3	was	be	VBD
cord-015935-r2wd1yfa	420	4	adjacent	adjacent	JJ
cord-015935-r2wd1yfa	420	5	to	to	IN
cord-015935-r2wd1yfa	420	6	SEMA5A	SEMA5A	NNP
cord-015935-r2wd1yfa	420	7	,	,	,
cord-015935-r2wd1yfa	420	8	a	a	DT
cord-015935-r2wd1yfa	420	9	member	member	NN
cord-015935-r2wd1yfa	420	10	of	of	IN
cord-015935-r2wd1yfa	420	11	the	the	DT
cord-015935-r2wd1yfa	420	12	semaphoring	semaphore	VBG
cord-015935-r2wd1yfa	420	13	axonal	axonal	JJ
cord-015935-r2wd1yfa	420	14	guidance	guidance	NN
cord-015935-r2wd1yfa	420	15	protein	protein	NN
cord-015935-r2wd1yfa	420	16	family	family	NN
cord-015935-r2wd1yfa	420	17	which	which	WDT
cord-015935-r2wd1yfa	420	18	has	have	VBZ
cord-015935-r2wd1yfa	420	19	been	be	VBN
cord-015935-r2wd1yfa	420	20	shown	show	VBN
cord-015935-r2wd1yfa	420	21	to	to	TO
cord-015935-r2wd1yfa	420	22	be	be	VB
cord-015935-r2wd1yfa	420	23	downregulated	downregulate	VBN
cord-015935-r2wd1yfa	420	24	in	in	IN
cord-015935-r2wd1yfa	420	25	transformed	transform	VBN
cord-015935-r2wd1yfa	420	26	B	b	NN
cord-015935-r2wd1yfa	420	27	lymphocytes	lymphocyte	NNS
cord-015935-r2wd1yfa	420	28	from	from	IN
cord-015935-r2wd1yfa	420	29	autism	autism	NN
cord-015935-r2wd1yfa	420	30	samples	sample	NNS
cord-015935-r2wd1yfa	420	31	(	(	-LRB-
cord-015935-r2wd1yfa	420	32	Weiss	Weiss	NNP
cord-015935-r2wd1yfa	420	33	et	et	NNP
cord-015935-r2wd1yfa	420	34	al	al	NNP
cord-015935-r2wd1yfa	420	35	.	.	NNP
cord-015935-r2wd1yfa	420	36	,	,	,
cord-015935-r2wd1yfa	420	37	2009	2009	CD
cord-015935-r2wd1yfa	420	38	)	)	-RRB-
cord-015935-r2wd1yfa	420	39	.	.	.
cord-015935-r2wd1yfa	421	1	The	the	DT
cord-015935-r2wd1yfa	421	2	authors	author	NNS
cord-015935-r2wd1yfa	421	3	further	further	RB
cord-015935-r2wd1yfa	421	4	demonstrated	demonstrate	VBD
cord-015935-r2wd1yfa	421	5	lower	low	JJR
cord-015935-r2wd1yfa	421	6	SEMA5A	SEMA5A	NNP
cord-015935-r2wd1yfa	421	7	gene	gene	NN
cord-015935-r2wd1yfa	421	8	expression	expression	NN
cord-015935-r2wd1yfa	421	9	in	in	IN
cord-015935-r2wd1yfa	421	10	autism	autism	NN
cord-015935-r2wd1yfa	421	11	brain	brain	NN
cord-015935-r2wd1yfa	421	12	tissue	tissue	NN
cord-015935-r2wd1yfa	421	13	.	.	.
cord-015935-r2wd1yfa	422	1	This	this	DT
cord-015935-r2wd1yfa	422	2	finding	finding	NN
cord-015935-r2wd1yfa	422	3	is	be	VBZ
cord-015935-r2wd1yfa	422	4	in	in	IN
cord-015935-r2wd1yfa	422	5	keeping	keep	VBG
cord-015935-r2wd1yfa	422	6	with	with	IN
cord-015935-r2wd1yfa	422	7	the	the	DT
cord-015935-r2wd1yfa	422	8	suspected	suspect	VBN
cord-015935-r2wd1yfa	422	9	derangement	derangement	NN
cord-015935-r2wd1yfa	422	10	in	in	IN
cord-015935-r2wd1yfa	422	11	the	the	DT
cord-015935-r2wd1yfa	422	12	migration	migration	NN
cord-015935-r2wd1yfa	422	13	of	of	IN
cord-015935-r2wd1yfa	422	14	cortical	cortical	JJ
cord-015935-r2wd1yfa	422	15	neurons	neuron	NNS
cord-015935-r2wd1yfa	422	16	during	during	IN
cord-015935-r2wd1yfa	422	17	embryogenesis	embryogenesis	NN
cord-015935-r2wd1yfa	422	18	in	in	IN
cord-015935-r2wd1yfa	422	19	autism	autism	NN
cord-015935-r2wd1yfa	422	20	.	.	.
cord-015935-r2wd1yfa	423	1	Microarray	Microarray	NNP
cord-015935-r2wd1yfa	423	2	technology	technology	NN
cord-015935-r2wd1yfa	423	3	is	be	VBZ
cord-015935-r2wd1yfa	423	4	transforming	transform	VBG
cord-015935-r2wd1yfa	423	5	the	the	DT
cord-015935-r2wd1yfa	423	6	identification	identification	NN
cord-015935-r2wd1yfa	423	7	of	of	IN
cord-015935-r2wd1yfa	423	8	chromosome	chromosome	NN
cord-015935-r2wd1yfa	423	9	duplications	duplication	NNS
cord-015935-r2wd1yfa	423	10	and	and	CC
cord-015935-r2wd1yfa	423	11	deletions	deletion	NNS
cord-015935-r2wd1yfa	423	12	(	(	-LRB-
cord-015935-r2wd1yfa	423	13	Gupta	Gupta	NNP
cord-015935-r2wd1yfa	423	14	&	&	CC
cord-015935-r2wd1yfa	423	15	State	State	NNP
cord-015935-r2wd1yfa	423	16	,	,	,
cord-015935-r2wd1yfa	423	17	2007	2007	CD
cord-015935-r2wd1yfa	423	18	)	)	-RRB-
cord-015935-r2wd1yfa	423	19	.	.	.
cord-015935-r2wd1yfa	424	1	This	this	DT
cord-015935-r2wd1yfa	424	2	new	new	JJ
cord-015935-r2wd1yfa	424	3	technology	technology	NN
cord-015935-r2wd1yfa	424	4	,	,	,
cord-015935-r2wd1yfa	424	5	known	know	VBN
cord-015935-r2wd1yfa	424	6	as	as	IN
cord-015935-r2wd1yfa	424	7	high	high	JJ
cord-015935-r2wd1yfa	424	8	-	-	HYPH
cord-015935-r2wd1yfa	424	9	density	density	NN
cord-015935-r2wd1yfa	424	10	,	,	,
cord-015935-r2wd1yfa	424	11	oligonucleotide	oligonucleotide	RB
cord-015935-r2wd1yfa	424	12	-	-	HYPH
cord-015935-r2wd1yfa	424	13	based	base	VBN
cord-015935-r2wd1yfa	424	14	array	array	NN
cord-015935-r2wd1yfa	424	15	comparative	comparative	JJ
cord-015935-r2wd1yfa	424	16	genomic	genomic	JJ
cord-015935-r2wd1yfa	424	17	hybridization	hybridization	NN
cord-015935-r2wd1yfa	424	18	(	(	-LRB-
cord-015935-r2wd1yfa	424	19	aCGH	aCGH	NNP
cord-015935-r2wd1yfa	424	20	)	)	-RRB-
cord-015935-r2wd1yfa	424	21	,	,	,
cord-015935-r2wd1yfa	424	22	is	be	VBZ
cord-015935-r2wd1yfa	424	23	now	now	RB
cord-015935-r2wd1yfa	424	24	available	available	JJ
cord-015935-r2wd1yfa	424	25	for	for	IN
cord-015935-r2wd1yfa	424	26	widespread	widespread	JJ
cord-015935-r2wd1yfa	424	27	use	use	NN
cord-015935-r2wd1yfa	424	28	.	.	.
cord-015935-r2wd1yfa	425	1	This	this	DT
cord-015935-r2wd1yfa	425	2	technique	technique	NN
cord-015935-r2wd1yfa	425	3	uses	use	VBZ
cord-015935-r2wd1yfa	425	4	patient	patient	JJ
cord-015935-r2wd1yfa	425	5	DNA	dna	NN
cord-015935-r2wd1yfa	425	6	and	and	CC
cord-015935-r2wd1yfa	425	7	control	control	NN
cord-015935-r2wd1yfa	425	8	DNA	dna	NN
cord-015935-r2wd1yfa	425	9	,	,	,
cord-015935-r2wd1yfa	425	10	each	each	DT
cord-015935-r2wd1yfa	425	11	labeled	label	VBN
cord-015935-r2wd1yfa	425	12	with	with	IN
cord-015935-r2wd1yfa	425	13	a	a	DT
cord-015935-r2wd1yfa	425	14	fluorescent	fluorescent	JJ
cord-015935-r2wd1yfa	425	15	tag	tag	NN
cord-015935-r2wd1yfa	425	16	(	(	-LRB-
cord-015935-r2wd1yfa	425	17	red	red	JJ
cord-015935-r2wd1yfa	425	18	or	or	CC
cord-015935-r2wd1yfa	425	19	green	green	JJ
cord-015935-r2wd1yfa	425	20	)	)	-RRB-
cord-015935-r2wd1yfa	425	21	.	.	.
cord-015935-r2wd1yfa	426	1	Equal	equal	JJ
cord-015935-r2wd1yfa	426	2	amounts	amount	NNS
cord-015935-r2wd1yfa	426	3	of	of	IN
cord-015935-r2wd1yfa	426	4	DNA	dna	NN
cord-015935-r2wd1yfa	426	5	from	from	IN
cord-015935-r2wd1yfa	426	6	patient	patient	NN
cord-015935-r2wd1yfa	426	7	and	and	CC
cord-015935-r2wd1yfa	426	8	control	control	NN
cord-015935-r2wd1yfa	426	9	are	be	VBP
cord-015935-r2wd1yfa	426	10	hybridized	hybridize	VBN
cord-015935-r2wd1yfa	426	11	to	to	IN
cord-015935-r2wd1yfa	426	12	known	know	VBN
cord-015935-r2wd1yfa	426	13	regions	region	NNS
cord-015935-r2wd1yfa	426	14	of	of	IN
cord-015935-r2wd1yfa	426	15	the	the	DT
cord-015935-r2wd1yfa	426	16	human	human	JJ
cord-015935-r2wd1yfa	426	17	genome	genome	NN
cord-015935-r2wd1yfa	426	18	pre	pre	VB
cord-015935-r2wd1yfa	426	19	-	-	VBN
cord-015935-r2wd1yfa	426	20	arrayed	array	VBN
cord-015935-r2wd1yfa	426	21	on	on	IN
cord-015935-r2wd1yfa	426	22	a	a	DT
cord-015935-r2wd1yfa	426	23	slide	slide	NN
cord-015935-r2wd1yfa	426	24	.	.	.
cord-015935-r2wd1yfa	427	1	If	if	IN
cord-015935-r2wd1yfa	427	2	patient	patient	JJ
cord-015935-r2wd1yfa	427	3	and	and	CC
cord-015935-r2wd1yfa	427	4	control	control	NN
cord-015935-r2wd1yfa	427	5	have	have	VBP
cord-015935-r2wd1yfa	427	6	equal	equal	JJ
cord-015935-r2wd1yfa	427	7	copy	copy	NN
cord-015935-r2wd1yfa	427	8	numbers	number	NNS
cord-015935-r2wd1yfa	427	9	at	at	IN
cord-015935-r2wd1yfa	427	10	a	a	DT
cord-015935-r2wd1yfa	427	11	given	give	VBN
cord-015935-r2wd1yfa	427	12	locus	locus	NN
cord-015935-r2wd1yfa	427	13	,	,	,
cord-015935-r2wd1yfa	427	14	the	the	DT
cord-015935-r2wd1yfa	427	15	color	color	NN
cord-015935-r2wd1yfa	427	16	turns	turn	VBZ
cord-015935-r2wd1yfa	427	17	yellow	yellow	JJ
cord-015935-r2wd1yfa	427	18	,	,	,
cord-015935-r2wd1yfa	427	19	representing	represent	VBG
cord-015935-r2wd1yfa	427	20	an	an	DT
cord-015935-r2wd1yfa	427	21	equal	equal	JJ
cord-015935-r2wd1yfa	427	22	measure	measure	NN
cord-015935-r2wd1yfa	427	23	of	of	IN
cord-015935-r2wd1yfa	427	24	DNA	dna	NN
cord-015935-r2wd1yfa	427	25	.	.	.
cord-015935-r2wd1yfa	428	1	If	if	IN
cord-015935-r2wd1yfa	428	2	the	the	DT
cord-015935-r2wd1yfa	428	3	patient	patient	NN
cord-015935-r2wd1yfa	428	4	has	have	VBZ
cord-015935-r2wd1yfa	428	5	lost	lose	VBN
cord-015935-r2wd1yfa	428	6	(	(	-LRB-
cord-015935-r2wd1yfa	428	7	deleted	delete	VBN
cord-015935-r2wd1yfa	428	8	)	)	-RRB-
cord-015935-r2wd1yfa	428	9	a	a	DT
cord-015935-r2wd1yfa	428	10	locus	locus	NN
cord-015935-r2wd1yfa	428	11	,	,	,
cord-015935-r2wd1yfa	428	12	only	only	RB
cord-015935-r2wd1yfa	428	13	the	the	DT
cord-015935-r2wd1yfa	428	14	control	control	NN
cord-015935-r2wd1yfa	428	15	color	color	NN
cord-015935-r2wd1yfa	428	16	is	be	VBZ
cord-015935-r2wd1yfa	428	17	visualized	visualize	VBN
cord-015935-r2wd1yfa	428	18	.	.	.
cord-015935-r2wd1yfa	429	1	If	if	IN
cord-015935-r2wd1yfa	429	2	the	the	DT
cord-015935-r2wd1yfa	429	3	patient	patient	NN
cord-015935-r2wd1yfa	429	4	has	have	VBZ
cord-015935-r2wd1yfa	429	5	an	an	DT
cord-015935-r2wd1yfa	429	6	extra	extra	JJ
cord-015935-r2wd1yfa	429	7	copy	copy	NN
cord-015935-r2wd1yfa	429	8	at	at	IN
cord-015935-r2wd1yfa	429	9	a	a	DT
cord-015935-r2wd1yfa	429	10	locus	locus	NN
cord-015935-r2wd1yfa	429	11	(	(	-LRB-
cord-015935-r2wd1yfa	429	12	duplication	duplication	NN
cord-015935-r2wd1yfa	429	13	)	)	-RRB-
cord-015935-r2wd1yfa	429	14	,	,	,
cord-015935-r2wd1yfa	429	15	the	the	DT
cord-015935-r2wd1yfa	429	16	patient	patient	NN
cord-015935-r2wd1yfa	429	17	color	color	NN
cord-015935-r2wd1yfa	429	18	predominates	predominate	VBZ
cord-015935-r2wd1yfa	429	19	.	.	.
cord-015935-r2wd1yfa	430	1	The	the	DT
cord-015935-r2wd1yfa	430	2	aCGH	acgh	JJ
cord-015935-r2wd1yfa	430	3	probe	probe	NN
cord-015935-r2wd1yfa	430	4	may	may	MD
cord-015935-r2wd1yfa	430	5	be	be	VB
cord-015935-r2wd1yfa	430	6	enriched	enrich	VBN
cord-015935-r2wd1yfa	430	7	for	for	IN
cord-015935-r2wd1yfa	430	8	known	know	VBN
cord-015935-r2wd1yfa	430	9	genes	gene	NNS
cord-015935-r2wd1yfa	430	10	or	or	CC
cord-015935-r2wd1yfa	430	11	specific	specific	JJ
cord-015935-r2wd1yfa	430	12	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	430	13	regions	region	NNS
cord-015935-r2wd1yfa	430	14	for	for	IN
cord-015935-r2wd1yfa	430	15	known	know	VBN
cord-015935-r2wd1yfa	430	16	syndromes	syndrome	NNS
cord-015935-r2wd1yfa	430	17	,	,	,
cord-015935-r2wd1yfa	430	18	or	or	CC
cord-015935-r2wd1yfa	430	19	distributed	distribute	VBN
cord-015935-r2wd1yfa	430	20	evenly	evenly	RB
cord-015935-r2wd1yfa	430	21	across	across	IN
cord-015935-r2wd1yfa	430	22	the	the	DT
cord-015935-r2wd1yfa	430	23	whole	whole	JJ
cord-015935-r2wd1yfa	430	24	genome	genome	NN
cord-015935-r2wd1yfa	430	25	.	.	.
cord-015935-r2wd1yfa	431	1	This	this	DT
cord-015935-r2wd1yfa	431	2	new	new	JJ
cord-015935-r2wd1yfa	431	3	technique	technique	NN
cord-015935-r2wd1yfa	431	4	is	be	VBZ
cord-015935-r2wd1yfa	431	5	now	now	RB
cord-015935-r2wd1yfa	431	6	available	available	JJ
cord-015935-r2wd1yfa	431	7	at	at	IN
cord-015935-r2wd1yfa	431	8	all	all	DT
cord-015935-r2wd1yfa	431	9	major	major	JJ
cord-015935-r2wd1yfa	431	10	medical	medical	JJ
cord-015935-r2wd1yfa	431	11	centers	center	NNS
cord-015935-r2wd1yfa	431	12	and	and	CC
cord-015935-r2wd1yfa	431	13	through	through	IN
cord-015935-r2wd1yfa	431	14	Signature	Signature	NNP
cord-015935-r2wd1yfa	431	15	Genomic	Genomic	NNP
cord-015935-r2wd1yfa	431	16	Laboratories	Laboratories	NNPS
cord-015935-r2wd1yfa	431	17	(	(	-LRB-
cord-015935-r2wd1yfa	431	18	www.signaturegenomics.com	www.signaturegenomics.com	ADD
cord-015935-r2wd1yfa	431	19	)	)	-RRB-
cord-015935-r2wd1yfa	431	20	.	.	.
cord-015935-r2wd1yfa	432	1	Single	single	JJ
cord-015935-r2wd1yfa	432	2	-	-	HYPH
cord-015935-r2wd1yfa	432	3	nucleotide	nucleotide	JJ
cord-015935-r2wd1yfa	432	4	polymorphism	polymorphism	NN
cord-015935-r2wd1yfa	432	5	(	(	-LRB-
cord-015935-r2wd1yfa	432	6	SNP	SNP	NNP
cord-015935-r2wd1yfa	432	7	)	)	-RRB-
cord-015935-r2wd1yfa	432	8	analysis	analysis	NN
cord-015935-r2wd1yfa	432	9	probes	probe	VBZ
cord-015935-r2wd1yfa	432	10	thousands	thousand	NNS
cord-015935-r2wd1yfa	432	11	of	of	IN
cord-015935-r2wd1yfa	432	12	SNPs	SNPs	NNPS
cord-015935-r2wd1yfa	432	13	and	and	CC
cord-015935-r2wd1yfa	432	14	provides	provide	VBZ
cord-015935-r2wd1yfa	432	15	data	datum	NNS
cord-015935-r2wd1yfa	432	16	about	about	IN
cord-015935-r2wd1yfa	432	17	copy	copy	NN
cord-015935-r2wd1yfa	432	18	number	number	NN
cord-015935-r2wd1yfa	432	19	and	and	CC
cord-015935-r2wd1yfa	432	20	genotype	genotype	NN
cord-015935-r2wd1yfa	432	21	(	(	-LRB-
cord-015935-r2wd1yfa	432	22	Li	Li	NNP
cord-015935-r2wd1yfa	432	23	&	&	CC
cord-015935-r2wd1yfa	432	24	Andersson	Andersson	NNP
cord-015935-r2wd1yfa	432	25	,	,	,
cord-015935-r2wd1yfa	432	26	2009	2009	CD
cord-015935-r2wd1yfa	432	27	)	)	-RRB-
cord-015935-r2wd1yfa	432	28	.	.	.
cord-015935-r2wd1yfa	433	1	The	the	DT
cord-015935-r2wd1yfa	433	2	genotype	genotype	NN
cord-015935-r2wd1yfa	433	3	can	can	MD
cord-015935-r2wd1yfa	433	4	be	be	VB
cord-015935-r2wd1yfa	433	5	used	use	VBN
cord-015935-r2wd1yfa	433	6	to	to	TO
cord-015935-r2wd1yfa	433	7	study	study	VB
cord-015935-r2wd1yfa	433	8	uniparental	uniparental	JJ
cord-015935-r2wd1yfa	433	9	disomy	disomy	NN
cord-015935-r2wd1yfa	433	10	(	(	-LRB-
cord-015935-r2wd1yfa	433	11	UPI	UPI	NNP
cord-015935-r2wd1yfa	433	12	)	)	-RRB-
cord-015935-r2wd1yfa	433	13	seen	see	VBN
cord-015935-r2wd1yfa	433	14	in	in	IN
cord-015935-r2wd1yfa	433	15	imprinting	imprinting	NN
cord-015935-r2wd1yfa	433	16	disorders	disorder	NNS
cord-015935-r2wd1yfa	433	17	and	and	CC
cord-015935-r2wd1yfa	433	18	consanguinity	consanguinity	NN
cord-015935-r2wd1yfa	433	19	.	.	.
cord-015935-r2wd1yfa	434	1	This	this	DT
cord-015935-r2wd1yfa	434	2	technique	technique	NN
cord-015935-r2wd1yfa	434	3	is	be	VBZ
cord-015935-r2wd1yfa	434	4	better	well	JJR
cord-015935-r2wd1yfa	434	5	at	at	IN
cord-015935-r2wd1yfa	434	6	focused	focused	JJ
cord-015935-r2wd1yfa	434	7	study	study	NN
cord-015935-r2wd1yfa	434	8	of	of	IN
cord-015935-r2wd1yfa	434	9	specific	specific	JJ
cord-015935-r2wd1yfa	434	10	gene	gene	NN
cord-015935-r2wd1yfa	434	11	regions	region	NNS
cord-015935-r2wd1yfa	434	12	instead	instead	RB
cord-015935-r2wd1yfa	434	13	of	of	IN
cord-015935-r2wd1yfa	434	14	the	the	DT
cord-015935-r2wd1yfa	434	15	whole	whole	JJ
cord-015935-r2wd1yfa	434	16	genome	genome	NN
cord-015935-r2wd1yfa	434	17	.	.	.
cord-015935-r2wd1yfa	435	1	Additionally	additionally	RB
cord-015935-r2wd1yfa	435	2	,	,	,
cord-015935-r2wd1yfa	435	3	SNP	SNP	NNP
cord-015935-r2wd1yfa	435	4	analysis	analysis	NN
cord-015935-r2wd1yfa	435	5	uses	use	VBZ
cord-015935-r2wd1yfa	435	6	pre	pre	VBN
cord-015935-r2wd1yfa	435	7	-	-	JJ
cord-015935-r2wd1yfa	435	8	established	establish	VBN
cord-015935-r2wd1yfa	435	9	laboratory	laboratory	NN
cord-015935-r2wd1yfa	435	10	standards	standard	NNS
cord-015935-r2wd1yfa	435	11	rather	rather	RB
cord-015935-r2wd1yfa	435	12	than	than	IN
cord-015935-r2wd1yfa	435	13	intraexperimental	intraexperimental	JJ
cord-015935-r2wd1yfa	435	14	controls	control	NNS
cord-015935-r2wd1yfa	435	15	.	.	.
cord-015935-r2wd1yfa	436	1	Both	both	DT
cord-015935-r2wd1yfa	436	2	SNP	SNP	NNP
cord-015935-r2wd1yfa	436	3	analysis	analysis	NN
cord-015935-r2wd1yfa	436	4	and	and	CC
cord-015935-r2wd1yfa	436	5	aCGH	aCGH	NNP
cord-015935-r2wd1yfa	436	6	map	map	NNP
cord-015935-r2wd1yfa	436	7	produce	produce	VBP
cord-015935-r2wd1yfa	436	8	copy	copy	NN
cord-015935-r2wd1yfa	436	9	number	number	NN
cord-015935-r2wd1yfa	436	10	variation	variation	NN
cord-015935-r2wd1yfa	436	11	,	,	,
cord-015935-r2wd1yfa	436	12	and	and	CC
cord-015935-r2wd1yfa	436	13	it	-PRON-	PRP
cord-015935-r2wd1yfa	436	14	is	be	VBZ
cord-015935-r2wd1yfa	436	15	common	common	JJ
cord-015935-r2wd1yfa	436	16	for	for	IN
cord-015935-r2wd1yfa	436	17	labs	lab	NNS
cord-015935-r2wd1yfa	436	18	to	to	TO
cord-015935-r2wd1yfa	436	19	first	first	RB
cord-015935-r2wd1yfa	436	20	perform	perform	VB
cord-015935-r2wd1yfa	436	21	aCGH	acgh	PRP
cord-015935-r2wd1yfa	436	22	and	and	CC
cord-015935-r2wd1yfa	436	23	follow	follow	VB
cord-015935-r2wd1yfa	436	24	up	up	RP
cord-015935-r2wd1yfa	436	25	with	with	IN
cord-015935-r2wd1yfa	436	26	SNP	SNP	NNP
cord-015935-r2wd1yfa	436	27	in	in	IN
cord-015935-r2wd1yfa	436	28	specific	specific	JJ
cord-015935-r2wd1yfa	436	29	regions	region	NNS
cord-015935-r2wd1yfa	436	30	of	of	IN
cord-015935-r2wd1yfa	436	31	interest	interest	NN
cord-015935-r2wd1yfa	436	32	.	.	.
cord-015935-r2wd1yfa	437	1	Today	today	NN
cord-015935-r2wd1yfa	437	2	,	,	,
cord-015935-r2wd1yfa	437	3	CNV	CNV	NNP
cord-015935-r2wd1yfa	437	4	from	from	IN
cord-015935-r2wd1yfa	437	5	several	several	JJ
cord-015935-r2wd1yfa	437	6	thousand	thousand	CD
cord-015935-r2wd1yfa	437	7	nucleotides	nucleotide	NNS
cord-015935-r2wd1yfa	437	8	can	can	MD
cord-015935-r2wd1yfa	437	9	be	be	VB
cord-015935-r2wd1yfa	437	10	identified	identify	VBN
cord-015935-r2wd1yfa	437	11	,	,	,
cord-015935-r2wd1yfa	437	12	greatly	greatly	RB
cord-015935-r2wd1yfa	437	13	improving	improve	VBG
cord-015935-r2wd1yfa	437	14	upon	upon	IN
cord-015935-r2wd1yfa	437	15	the	the	DT
cord-015935-r2wd1yfa	437	16	sensitivity	sensitivity	NN
cord-015935-r2wd1yfa	437	17	of	of	IN
cord-015935-r2wd1yfa	437	18	conventional	conventional	JJ
cord-015935-r2wd1yfa	437	19	cytogenetics	cytogenetic	NNS
cord-015935-r2wd1yfa	437	20	.	.	.
cord-015935-r2wd1yfa	438	1	Sebat	Sebat	NNP
cord-015935-r2wd1yfa	438	2	et	et	NNP
cord-015935-r2wd1yfa	438	3	al	al	NNP
cord-015935-r2wd1yfa	438	4	.	.	.
cord-015935-r2wd1yfa	439	1	(	(	-LRB-
cord-015935-r2wd1yfa	439	2	2007	2007	CD
cord-015935-r2wd1yfa	439	3	)	)	-RRB-
cord-015935-r2wd1yfa	439	4	showed	show	VBD
cord-015935-r2wd1yfa	439	5	that	that	IN
cord-015935-r2wd1yfa	439	6	CNVs	cnv	NNS
cord-015935-r2wd1yfa	439	7	were	be	VBD
cord-015935-r2wd1yfa	439	8	present	present	JJ
cord-015935-r2wd1yfa	439	9	in	in	IN
cord-015935-r2wd1yfa	439	10	10	10	CD
cord-015935-r2wd1yfa	439	11	%	%	NN
cord-015935-r2wd1yfa	439	12	of	of	IN
cord-015935-r2wd1yfa	439	13	affected	affect	VBN
cord-015935-r2wd1yfa	439	14	individuals	individual	NNS
cord-015935-r2wd1yfa	439	15	from	from	IN
cord-015935-r2wd1yfa	439	16	singleincidence	singleincidence	NNP
cord-015935-r2wd1yfa	439	17	autism	autism	NN
cord-015935-r2wd1yfa	439	18	families	family	NNS
cord-015935-r2wd1yfa	439	19	(	(	-LRB-
cord-015935-r2wd1yfa	439	20	i.e.	i.e.	FW
cord-015935-r2wd1yfa	439	21	,	,	,
cord-015935-r2wd1yfa	439	22	sporadic	sporadic	JJ
cord-015935-r2wd1yfa	439	23	cases	case	NNS
cord-015935-r2wd1yfa	439	24	)	)	-RRB-
cord-015935-r2wd1yfa	439	25	,	,	,
cord-015935-r2wd1yfa	439	26	contrasting	contrast	VBG
cord-015935-r2wd1yfa	439	27	with	with	IN
cord-015935-r2wd1yfa	439	28	substantially	substantially	RB
cord-015935-r2wd1yfa	439	29	lower	low	JJR
cord-015935-r2wd1yfa	439	30	rates	rate	NNS
cord-015935-r2wd1yfa	439	31	observed	observe	VBN
cord-015935-r2wd1yfa	439	32	in	in	IN
cord-015935-r2wd1yfa	439	33	controls	control	NNS
cord-015935-r2wd1yfa	439	34	(	(	-LRB-
cord-015935-r2wd1yfa	439	35	1	1	CD
cord-015935-r2wd1yfa	439	36	%	%	NN
cord-015935-r2wd1yfa	439	37	)	)	-RRB-
cord-015935-r2wd1yfa	439	38	and	and	CC
cord-015935-r2wd1yfa	439	39	autism	autism	NN
cord-015935-r2wd1yfa	439	40	cases	case	NNS
cord-015935-r2wd1yfa	439	41	from	from	IN
cord-015935-r2wd1yfa	439	42	multiplex	multiplex	JJ
cord-015935-r2wd1yfa	439	43	families	family	NNS
cord-015935-r2wd1yfa	439	44	(	(	-LRB-
cord-015935-r2wd1yfa	439	45	3	3	CD
cord-015935-r2wd1yfa	439	46	%	%	NN
cord-015935-r2wd1yfa	439	47	)	)	-RRB-
cord-015935-r2wd1yfa	439	48	.	.	.
cord-015935-r2wd1yfa	440	1	This	this	DT
cord-015935-r2wd1yfa	440	2	has	have	VBZ
cord-015935-r2wd1yfa	440	3	led	lead	VBN
cord-015935-r2wd1yfa	440	4	to	to	IN
cord-015935-r2wd1yfa	440	5	the	the	DT
cord-015935-r2wd1yfa	440	6	general	general	JJ
cord-015935-r2wd1yfa	440	7	expectation	expectation	NN
cord-015935-r2wd1yfa	440	8	that	that	IN
cord-015935-r2wd1yfa	440	9	de	de	NNP
cord-015935-r2wd1yfa	440	10	novo	novo	NNP
cord-015935-r2wd1yfa	440	11	CNVs	CNVs	NNPS
cord-015935-r2wd1yfa	440	12	are	be	VBP
cord-015935-r2wd1yfa	440	13	more	more	RBR
cord-015935-r2wd1yfa	440	14	likely	likely	JJ
cord-015935-r2wd1yfa	440	15	to	to	TO
cord-015935-r2wd1yfa	440	16	be	be	VB
cord-015935-r2wd1yfa	440	17	found	find	VBN
cord-015935-r2wd1yfa	440	18	in	in	IN
cord-015935-r2wd1yfa	440	19	sporadic	sporadic	JJ
cord-015935-r2wd1yfa	440	20	(	(	-LRB-
cord-015935-r2wd1yfa	440	21	and	and	CC
cord-015935-r2wd1yfa	440	22	as	as	IN
cord-015935-r2wd1yfa	440	23	it	-PRON-	PRP
cord-015935-r2wd1yfa	440	24	turns	turn	VBZ
cord-015935-r2wd1yfa	440	25	out	out	RP
cord-015935-r2wd1yfa	440	26	,	,	,
cord-015935-r2wd1yfa	440	27	dysmorphic	dysmorphic	JJ
cord-015935-r2wd1yfa	440	28	)	)	-RRB-
cord-015935-r2wd1yfa	440	29	cases	case	NNS
cord-015935-r2wd1yfa	440	30	.	.	.
cord-015935-r2wd1yfa	441	1	Jacquemont	Jacquemont	NNP
cord-015935-r2wd1yfa	441	2	et	et	NNP
cord-015935-r2wd1yfa	441	3	al	al	NNP
cord-015935-r2wd1yfa	441	4	.	.	.
cord-015935-r2wd1yfa	442	1	,	,	,
cord-015935-r2wd1yfa	442	2	2006	2006	CD
cord-015935-r2wd1yfa	442	3	reported	report	VBD
cord-015935-r2wd1yfa	442	4	CNV	CNV	NNP
cord-015935-r2wd1yfa	442	5	rearrangements	rearrangement	NNS
cord-015935-r2wd1yfa	442	6	in	in	IN
cord-015935-r2wd1yfa	442	7	8	8	CD
cord-015935-r2wd1yfa	442	8	(	(	-LRB-
cord-015935-r2wd1yfa	442	9	27.5	27.5	CD
cord-015935-r2wd1yfa	442	10	%	%	NN
cord-015935-r2wd1yfa	442	11	)	)	-RRB-
cord-015935-r2wd1yfa	442	12	of	of	IN
cord-015935-r2wd1yfa	442	13	29	29	CD
cord-015935-r2wd1yfa	442	14	patients	patient	NNS
cord-015935-r2wd1yfa	442	15	with	with	IN
cord-015935-r2wd1yfa	442	16	syndromic	syndromic	NNP
cord-015935-r2wd1yfa	442	17	autism	autism	NN
cord-015935-r2wd1yfa	442	18	(	(	-LRB-
cord-015935-r2wd1yfa	442	19	including	include	VBG
cord-015935-r2wd1yfa	442	20	facial	facial	JJ
cord-015935-r2wd1yfa	442	21	dysmorphism	dysmorphism	NN
cord-015935-r2wd1yfa	442	22	,	,	,
cord-015935-r2wd1yfa	442	23	limb	limb	NN
cord-015935-r2wd1yfa	442	24	or	or	CC
cord-015935-r2wd1yfa	442	25	visceral	visceral	JJ
cord-015935-r2wd1yfa	442	26	malformations	malformation	NNS
cord-015935-r2wd1yfa	442	27	,	,	,
cord-015935-r2wd1yfa	442	28	and	and	CC
cord-015935-r2wd1yfa	442	29	growth	growth	NN
cord-015935-r2wd1yfa	442	30	abnormalities	abnormality	NNS
cord-015935-r2wd1yfa	442	31	)	)	-RRB-
cord-015935-r2wd1yfa	442	32	.	.	.
cord-015935-r2wd1yfa	443	1	There	there	EX
cord-015935-r2wd1yfa	443	2	were	be	VBD
cord-015935-r2wd1yfa	443	3	no	no	DT
cord-015935-r2wd1yfa	443	4	reoccurrence	reoccurrence	NN
cord-015935-r2wd1yfa	443	5	or	or	CC
cord-015935-r2wd1yfa	443	6	overlap	overlap	VB
cord-015935-r2wd1yfa	443	7	in	in	IN
cord-015935-r2wd1yfa	443	8	these	these	DT
cord-015935-r2wd1yfa	443	9	variants	variant	NNS
cord-015935-r2wd1yfa	443	10	for	for	IN
cord-015935-r2wd1yfa	443	11	the	the	DT
cord-015935-r2wd1yfa	443	12	eight	eight	CD
cord-015935-r2wd1yfa	443	13	children	child	NNS
cord-015935-r2wd1yfa	443	14	.	.	.
cord-015935-r2wd1yfa	444	1	Chromosome	chromosome	NN
cord-015935-r2wd1yfa	444	2	11q12-p13	11q12-p13	NN
cord-015935-r2wd1yfa	444	3	and	and	CC
cord-015935-r2wd1yfa	444	4	neurexins	neurexin	NNS
cord-015935-r2wd1yfa	444	5	were	be	VBD
cord-015935-r2wd1yfa	444	6	implicated	implicate	VBN
cord-015935-r2wd1yfa	444	7	in	in	IN
cord-015935-r2wd1yfa	444	8	a	a	DT
cord-015935-r2wd1yfa	444	9	linkage	linkage	NN
cord-015935-r2wd1yfa	444	10	study	study	NN
cord-015935-r2wd1yfa	444	11	using	use	VBG
cord-015935-r2wd1yfa	444	12	SNP	SNP	NNP
cord-015935-r2wd1yfa	444	13	-	-	HYPH
cord-015935-r2wd1yfa	444	14	CNV	CNV	NNP
cord-015935-r2wd1yfa	444	15	in	in	IN
cord-015935-r2wd1yfa	444	16	1,181	1,181	CD
cord-015935-r2wd1yfa	444	17	families	family	NNS
cord-015935-r2wd1yfa	444	18	with	with	IN
cord-015935-r2wd1yfa	444	19	at	at	RB
cord-015935-r2wd1yfa	444	20	least	least	RBS
cord-015935-r2wd1yfa	444	21	two	two	CD
cord-015935-r2wd1yfa	444	22	affected	affect	VBN
cord-015935-r2wd1yfa	444	23	individuals	individual	NNS
cord-015935-r2wd1yfa	444	24	through	through	IN
cord-015935-r2wd1yfa	444	25	the	the	DT
cord-015935-r2wd1yfa	444	26	Autism	Autism	NNP
cord-015935-r2wd1yfa	444	27	Genome	Genome	NNP
cord-015935-r2wd1yfa	444	28	Project	Project	NNP
cord-015935-r2wd1yfa	445	1	(	(	-LRB-
cord-015935-r2wd1yfa	445	2	Szatmari	Szatmari	NNP
cord-015935-r2wd1yfa	445	3	et	et	NNP
cord-015935-r2wd1yfa	445	4	al	al	NNP
cord-015935-r2wd1yfa	445	5	.	.	NNP
cord-015935-r2wd1yfa	445	6	,	,	,
cord-015935-r2wd1yfa	445	7	2007	2007	CD
cord-015935-r2wd1yfa	445	8	)	)	-RRB-
cord-015935-r2wd1yfa	445	9	.	.	.
cord-015935-r2wd1yfa	446	1	Microarray	Microarray	NNP
cord-015935-r2wd1yfa	446	2	technology	technology	NN
cord-015935-r2wd1yfa	446	3	,	,	,
cord-015935-r2wd1yfa	446	4	however	however	RB
cord-015935-r2wd1yfa	446	5	,	,	,
cord-015935-r2wd1yfa	446	6	comes	come	VBZ
cord-015935-r2wd1yfa	446	7	with	with	IN
cord-015935-r2wd1yfa	446	8	the	the	DT
cord-015935-r2wd1yfa	446	9	realization	realization	NN
cord-015935-r2wd1yfa	446	10	that	that	WDT
cord-015935-r2wd1yfa	446	11	typically	typically	RB
cord-015935-r2wd1yfa	446	12	developing	develop	VBG
cord-015935-r2wd1yfa	446	13	individuals	individual	NNS
cord-015935-r2wd1yfa	446	14	have	have	VBP
cord-015935-r2wd1yfa	446	15	more	more	JJR
cord-015935-r2wd1yfa	446	16	structural	structural	JJ
cord-015935-r2wd1yfa	446	17	variants	variant	NNS
cord-015935-r2wd1yfa	446	18	than	than	IN
cord-015935-r2wd1yfa	446	19	previously	previously	RB
cord-015935-r2wd1yfa	446	20	imagined	imagine	VBN
cord-015935-r2wd1yfa	447	1	(	(	-LRB-
cord-015935-r2wd1yfa	447	2	Sebat	Sebat	NNP
cord-015935-r2wd1yfa	447	3	et	et	NNP
cord-015935-r2wd1yfa	447	4	al	al	NNP
cord-015935-r2wd1yfa	447	5	.	.	NNP
cord-015935-r2wd1yfa	447	6	,	,	,
cord-015935-r2wd1yfa	447	7	2007	2007	CD
cord-015935-r2wd1yfa	447	8	)	)	-RRB-
cord-015935-r2wd1yfa	447	9	.	.	.
cord-015935-r2wd1yfa	448	1	There	there	EX
cord-015935-r2wd1yfa	448	2	is	be	VBZ
cord-015935-r2wd1yfa	448	3	growing	grow	VBG
cord-015935-r2wd1yfa	448	4	concern	concern	NN
cord-015935-r2wd1yfa	448	5	that	that	IN
cord-015935-r2wd1yfa	448	6	CNV	CNV	NNP
cord-015935-r2wd1yfa	448	7	irregularities	irregularity	NNS
cord-015935-r2wd1yfa	448	8	may	may	MD
cord-015935-r2wd1yfa	448	9	not	not	RB
cord-015935-r2wd1yfa	448	10	be	be	VB
cord-015935-r2wd1yfa	448	11	pathological	pathological	JJ
cord-015935-r2wd1yfa	448	12	and	and	CC
cord-015935-r2wd1yfa	448	13	therefore	therefore	RB
cord-015935-r2wd1yfa	448	14	not	not	RB
cord-015935-r2wd1yfa	448	15	be	be	VB
cord-015935-r2wd1yfa	448	16	a	a	DT
cord-015935-r2wd1yfa	448	17	cause	cause	NN
cord-015935-r2wd1yfa	448	18	of	of	IN
cord-015935-r2wd1yfa	448	19	autism	autism	NN
cord-015935-r2wd1yfa	448	20	(	(	-LRB-
cord-015935-r2wd1yfa	448	21	Tabor	Tabor	NNP
cord-015935-r2wd1yfa	448	22	&	&	CC
cord-015935-r2wd1yfa	448	23	Cho	Cho	NNP
cord-015935-r2wd1yfa	448	24	,	,	,
cord-015935-r2wd1yfa	448	25	2007	2007	CD
cord-015935-r2wd1yfa	448	26	)	)	-RRB-
cord-015935-r2wd1yfa	448	27	.	.	.
cord-015935-r2wd1yfa	449	1	These	these	DT
cord-015935-r2wd1yfa	449	2	authors	author	NNS
cord-015935-r2wd1yfa	449	3	note	note	VBP
cord-015935-r2wd1yfa	449	4	that	that	IN
cord-015935-r2wd1yfa	449	5	using	use	VBG
cord-015935-r2wd1yfa	449	6	diagnostic	diagnostic	JJ
cord-015935-r2wd1yfa	449	7	tools	tool	NNS
cord-015935-r2wd1yfa	449	8	prematurely	prematurely	RB
cord-015935-r2wd1yfa	449	9	in	in	IN
cord-015935-r2wd1yfa	449	10	a	a	DT
cord-015935-r2wd1yfa	449	11	clinical	clinical	JJ
cord-015935-r2wd1yfa	449	12	context	context	NN
cord-015935-r2wd1yfa	449	13	may	may	MD
cord-015935-r2wd1yfa	449	14	be	be	VB
cord-015935-r2wd1yfa	449	15	"	"	``
cord-015935-r2wd1yfa	449	16	unethical	unethical	JJ
cord-015935-r2wd1yfa	449	17	,	,	,
cord-015935-r2wd1yfa	449	18	either	either	CC
cord-015935-r2wd1yfa	449	19	because	because	IN
cord-015935-r2wd1yfa	449	20	of	of	IN
cord-015935-r2wd1yfa	449	21	over	over	IN
cord-015935-r2wd1yfa	449	22	-	-	HYPH
cord-015935-r2wd1yfa	449	23	treatment	treatment	NN
cord-015935-r2wd1yfa	449	24	,	,	,
cord-015935-r2wd1yfa	449	25	under	under	IN
cord-015935-r2wd1yfa	449	26	-	-	HYPH
cord-015935-r2wd1yfa	449	27	treatment	treatment	NN
cord-015935-r2wd1yfa	449	28	,	,	,
cord-015935-r2wd1yfa	449	29	unwarranted	unwarranted	JJ
cord-015935-r2wd1yfa	449	30	labeling	labeling	NN
cord-015935-r2wd1yfa	449	31	and	and	CC
cord-015935-r2wd1yfa	449	32	stigmatization	stigmatization	NN
cord-015935-r2wd1yfa	449	33	,	,	,
cord-015935-r2wd1yfa	449	34	or	or	CC
cord-015935-r2wd1yfa	449	35	a	a	DT
cord-015935-r2wd1yfa	449	36	false	false	JJ
cord-015935-r2wd1yfa	449	37	sense	sense	NN
cord-015935-r2wd1yfa	449	38	of	of	IN
cord-015935-r2wd1yfa	449	39	security	security	NN
cord-015935-r2wd1yfa	449	40	.	.	.
cord-015935-r2wd1yfa	449	41	"	"	''
cord-015935-r2wd1yfa	450	1	Certainly	certainly	RB
cord-015935-r2wd1yfa	450	2	,	,	,
cord-015935-r2wd1yfa	450	3	further	further	JJ
cord-015935-r2wd1yfa	450	4	studies	study	NNS
cord-015935-r2wd1yfa	450	5	on	on	IN
cord-015935-r2wd1yfa	450	6	large	large	JJ
cord-015935-r2wd1yfa	450	7	cohorts	cohort	NNS
cord-015935-r2wd1yfa	450	8	of	of	IN
cord-015935-r2wd1yfa	450	9	children	child	NNS
cord-015935-r2wd1yfa	450	10	with	with	IN
cord-015935-r2wd1yfa	450	11	the	the	DT
cord-015935-r2wd1yfa	450	12	same	same	JJ
cord-015935-r2wd1yfa	450	13	deletion	deletion	NN
cord-015935-r2wd1yfa	450	14	/	/	SYM
cord-015935-r2wd1yfa	450	15	duplication	duplication	NN
cord-015935-r2wd1yfa	450	16	are	be	VBP
cord-015935-r2wd1yfa	450	17	necessary	necessary	JJ
cord-015935-r2wd1yfa	450	18	to	to	TO
cord-015935-r2wd1yfa	450	19	enable	enable	VB
cord-015935-r2wd1yfa	450	20	clinical	clinical	JJ
cord-015935-r2wd1yfa	450	21	application	application	NN
cord-015935-r2wd1yfa	450	22	of	of	IN
cord-015935-r2wd1yfa	450	23	this	this	DT
cord-015935-r2wd1yfa	450	24	technology	technology	NN
cord-015935-r2wd1yfa	450	25	.	.	.
cord-015935-r2wd1yfa	451	1	Due	due	IN
cord-015935-r2wd1yfa	451	2	to	to	IN
cord-015935-r2wd1yfa	451	3	the	the	DT
cord-015935-r2wd1yfa	451	4	phenotypic	phenotypic	JJ
cord-015935-r2wd1yfa	451	5	heterogeneity	heterogeneity	NN
cord-015935-r2wd1yfa	451	6	of	of	IN
cord-015935-r2wd1yfa	451	7	autism	autism	NN
cord-015935-r2wd1yfa	451	8	and	and	CC
cord-015935-r2wd1yfa	451	9	the	the	DT
cord-015935-r2wd1yfa	451	10	lack	lack	NN
cord-015935-r2wd1yfa	451	11	of	of	IN
cord-015935-r2wd1yfa	451	12	finding	find	VBG
cord-015935-r2wd1yfa	451	13	a	a	DT
cord-015935-r2wd1yfa	451	14	specific	specific	JJ
cord-015935-r2wd1yfa	451	15	gene	gene	NN
cord-015935-r2wd1yfa	451	16	,	,	,
cord-015935-r2wd1yfa	451	17	researchers	researcher	NNS
cord-015935-r2wd1yfa	451	18	have	have	VBP
cord-015935-r2wd1yfa	451	19	narrowed	narrow	VBN
cord-015935-r2wd1yfa	451	20	the	the	DT
cord-015935-r2wd1yfa	451	21	scope	scope	NN
cord-015935-r2wd1yfa	451	22	of	of	IN
cord-015935-r2wd1yfa	451	23	analysis	analysis	NN
cord-015935-r2wd1yfa	451	24	to	to	IN
cord-015935-r2wd1yfa	451	25	more	more	RBR
cord-015935-r2wd1yfa	451	26	pure	pure	JJ
cord-015935-r2wd1yfa	451	27	,	,	,
cord-015935-r2wd1yfa	451	28	operationally	operationally	RB
cord-015935-r2wd1yfa	451	29	defined	define	VBN
cord-015935-r2wd1yfa	451	30	behaviors	behavior	NNS
cord-015935-r2wd1yfa	451	31	/	/	SYM
cord-015935-r2wd1yfa	451	32	traits	trait	NNS
cord-015935-r2wd1yfa	451	33	.	.	.
cord-015935-r2wd1yfa	452	1	Endophenotypes	endophenotype	NNS
cord-015935-r2wd1yfa	452	2	are	be	VBP
cord-015935-r2wd1yfa	452	3	behavioral	behavioral	JJ
cord-015935-r2wd1yfa	452	4	,	,	,
cord-015935-r2wd1yfa	452	5	physiological	physiological	JJ
cord-015935-r2wd1yfa	452	6	,	,	,
cord-015935-r2wd1yfa	452	7	and/or	and/or	CC
cord-015935-r2wd1yfa	452	8	neuropsychological	neuropsychological	JJ
cord-015935-r2wd1yfa	452	9	markers	marker	NNS
cord-015935-r2wd1yfa	452	10	that	that	WDT
cord-015935-r2wd1yfa	452	11	are	be	VBP
cord-015935-r2wd1yfa	452	12	present	present	JJ
cord-015935-r2wd1yfa	452	13	in	in	IN
cord-015935-r2wd1yfa	452	14	both	both	CC
cord-015935-r2wd1yfa	452	15	affected	affected	JJ
cord-015935-r2wd1yfa	452	16	and	and	CC
cord-015935-r2wd1yfa	452	17	unaffected	unaffected	JJ
cord-015935-r2wd1yfa	452	18	individuals	individual	NNS
cord-015935-r2wd1yfa	452	19	.	.	.
cord-015935-r2wd1yfa	453	1	Rather	rather	RB
cord-015935-r2wd1yfa	453	2	than	than	IN
cord-015935-r2wd1yfa	453	3	searching	search	VBG
cord-015935-r2wd1yfa	453	4	for	for	IN
cord-015935-r2wd1yfa	453	5	"	"	``
cord-015935-r2wd1yfa	453	6	autism	autism	NN
cord-015935-r2wd1yfa	453	7	genes	gene	NNS
cord-015935-r2wd1yfa	453	8	,	,	,
cord-015935-r2wd1yfa	453	9	"	"	``
cord-015935-r2wd1yfa	453	10	endophenotype	endophenotype	NN
cord-015935-r2wd1yfa	453	11	investigations	investigation	NNS
cord-015935-r2wd1yfa	453	12	search	search	VBP
cord-015935-r2wd1yfa	453	13	for	for	IN
cord-015935-r2wd1yfa	453	14	smaller	small	JJR
cord-015935-r2wd1yfa	453	15	grouping	grouping	NN
cord-015935-r2wd1yfa	453	16	of	of	IN
cord-015935-r2wd1yfa	453	17	genes	gene	NNS
cord-015935-r2wd1yfa	453	18	that	that	WDT
cord-015935-r2wd1yfa	453	19	contribute	contribute	VBP
cord-015935-r2wd1yfa	453	20	to	to	IN
cord-015935-r2wd1yfa	453	21	discreet	discreet	JJ
cord-015935-r2wd1yfa	453	22	phenotypes	phenotype	NNS
cord-015935-r2wd1yfa	453	23	(	(	-LRB-
cord-015935-r2wd1yfa	453	24	Losh	Losh	NNP
cord-015935-r2wd1yfa	453	25	et	et	NNP
cord-015935-r2wd1yfa	453	26	al	al	NNP
cord-015935-r2wd1yfa	453	27	.	.	NNP
cord-015935-r2wd1yfa	453	28	,	,	,
cord-015935-r2wd1yfa	453	29	2008	2008	CD
cord-015935-r2wd1yfa	453	30	)	)	-RRB-
cord-015935-r2wd1yfa	453	31	.	.	.
cord-015935-r2wd1yfa	454	1	This	this	DT
cord-015935-r2wd1yfa	454	2	approach	approach	NN
cord-015935-r2wd1yfa	454	3	allows	allow	VBZ
cord-015935-r2wd1yfa	454	4	for	for	IN
cord-015935-r2wd1yfa	454	5	measurement	measurement	NN
cord-015935-r2wd1yfa	454	6	of	of	IN
cord-015935-r2wd1yfa	454	7	"	"	``
cord-015935-r2wd1yfa	454	8	dosage	dosage	NN
cord-015935-r2wd1yfa	454	9	"	"	''
cord-015935-r2wd1yfa	454	10	of	of	IN
cord-015935-r2wd1yfa	454	11	a	a	DT
cord-015935-r2wd1yfa	454	12	trait	trait	NN
cord-015935-r2wd1yfa	454	13	and	and	CC
cord-015935-r2wd1yfa	454	14	can	can	MD
cord-015935-r2wd1yfa	454	15	be	be	VB
cord-015935-r2wd1yfa	454	16	applied	apply	VBN
cord-015935-r2wd1yfa	454	17	to	to	IN
cord-015935-r2wd1yfa	454	18	affected	affect	VBN
cord-015935-r2wd1yfa	454	19	as	as	RB
cord-015935-r2wd1yfa	454	20	well	well	RB
cord-015935-r2wd1yfa	454	21	as	as	IN
cord-015935-r2wd1yfa	454	22	unaffected	unaffected	JJ
cord-015935-r2wd1yfa	454	23	individuals	individual	NNS
cord-015935-r2wd1yfa	454	24	.	.	.
cord-015935-r2wd1yfa	455	1	Specific	specific	JJ
cord-015935-r2wd1yfa	455	2	language	language	NN
cord-015935-r2wd1yfa	455	3	impairment	impairment	NN
cord-015935-r2wd1yfa	455	4	(	(	-LRB-
cord-015935-r2wd1yfa	455	5	SLI	SLI	NNP
cord-015935-r2wd1yfa	455	6	)	)	-RRB-
cord-015935-r2wd1yfa	455	7	is	be	VBZ
cord-015935-r2wd1yfa	455	8	defined	define	VBN
cord-015935-r2wd1yfa	455	9	as	as	IN
cord-015935-r2wd1yfa	455	10	the	the	DT
cord-015935-r2wd1yfa	455	11	failure	failure	NN
cord-015935-r2wd1yfa	455	12	of	of	IN
cord-015935-r2wd1yfa	455	13	normal	normal	JJ
cord-015935-r2wd1yfa	455	14	development	development	NN
cord-015935-r2wd1yfa	455	15	of	of	IN
cord-015935-r2wd1yfa	455	16	language	language	NN
cord-015935-r2wd1yfa	455	17	without	without	IN
cord-015935-r2wd1yfa	455	18	hearing	hear	VBG
cord-015935-r2wd1yfa	455	19	loss	loss	NN
cord-015935-r2wd1yfa	455	20	,	,	,
cord-015935-r2wd1yfa	455	21	mental	mental	JJ
cord-015935-r2wd1yfa	455	22	retardation	retardation	NN
cord-015935-r2wd1yfa	455	23	,	,	,
cord-015935-r2wd1yfa	455	24	or	or	CC
cord-015935-r2wd1yfa	455	25	oral	oral	JJ
cord-015935-r2wd1yfa	455	26	motor	motor	NN
cord-015935-r2wd1yfa	455	27	,	,	,
cord-015935-r2wd1yfa	455	28	neurological	neurological	JJ
cord-015935-r2wd1yfa	455	29	,	,	,
cord-015935-r2wd1yfa	455	30	or	or	CC
cord-015935-r2wd1yfa	455	31	psychiatric	psychiatric	JJ
cord-015935-r2wd1yfa	455	32	impairment	impairment	NN
cord-015935-r2wd1yfa	455	33	.	.	.
cord-015935-r2wd1yfa	456	1	This	this	DT
cord-015935-r2wd1yfa	456	2	affects	affect	VBZ
cord-015935-r2wd1yfa	456	3	approximately	approximately	RB
cord-015935-r2wd1yfa	456	4	7	7	CD
cord-015935-r2wd1yfa	456	5	%	%	NN
cord-015935-r2wd1yfa	456	6	of	of	IN
cord-015935-r2wd1yfa	456	7	children	child	NNS
cord-015935-r2wd1yfa	456	8	entering	enter	VBG
cord-015935-r2wd1yfa	456	9	school	school	NN
cord-015935-r2wd1yfa	457	1	(	(	-LRB-
cord-015935-r2wd1yfa	457	2	Tomblin	Tomblin	NNP
cord-015935-r2wd1yfa	457	3	et	et	NNP
cord-015935-r2wd1yfa	457	4	al	al	NNP
cord-015935-r2wd1yfa	457	5	.	.	NNP
cord-015935-r2wd1yfa	457	6	,	,	,
cord-015935-r2wd1yfa	457	7	1997	1997	CD
cord-015935-r2wd1yfa	457	8	)	)	-RRB-
cord-015935-r2wd1yfa	457	9	.	.	.
cord-015935-r2wd1yfa	458	1	Individuals	individual	NNS
cord-015935-r2wd1yfa	458	2	with	with	IN
cord-015935-r2wd1yfa	458	3	SLI	SLI	NNP
cord-015935-r2wd1yfa	458	4	perform	perform	VBP
cord-015935-r2wd1yfa	458	5	poorly	poorly	RB
cord-015935-r2wd1yfa	458	6	on	on	IN
cord-015935-r2wd1yfa	458	7	phonologically	phonologically	RB
cord-015935-r2wd1yfa	458	8	based	base	VBN
cord-015935-r2wd1yfa	458	9	tasks	task	NNS
cord-015935-r2wd1yfa	458	10	and	and	CC
cord-015935-r2wd1yfa	458	11	many	many	JJ
cord-015935-r2wd1yfa	458	12	go	go	VBP
cord-015935-r2wd1yfa	458	13	on	on	RP
cord-015935-r2wd1yfa	458	14	to	to	TO
cord-015935-r2wd1yfa	458	15	develop	develop	VB
cord-015935-r2wd1yfa	458	16	dyslexia	dyslexia	NNP
cord-015935-r2wd1yfa	458	17	(	(	-LRB-
cord-015935-r2wd1yfa	458	18	Stothard	Stothard	NNP
cord-015935-r2wd1yfa	458	19	,	,	,
cord-015935-r2wd1yfa	458	20	Snowling	Snowling	NNP
cord-015935-r2wd1yfa	458	21	,	,	,
cord-015935-r2wd1yfa	458	22	Bishop	Bishop	NNP
cord-015935-r2wd1yfa	458	23	,	,	,
cord-015935-r2wd1yfa	458	24	Chipchase	Chipchase	NNP
cord-015935-r2wd1yfa	458	25	,	,	,
cord-015935-r2wd1yfa	458	26	&	&	CC
cord-015935-r2wd1yfa	458	27	Kaplan	Kaplan	NNP
cord-015935-r2wd1yfa	458	28	,	,	,
cord-015935-r2wd1yfa	458	29	1998	1998	CD
cord-015935-r2wd1yfa	458	30	)	)	-RRB-
cord-015935-r2wd1yfa	458	31	.	.	.
cord-015935-r2wd1yfa	459	1	There	there	EX
cord-015935-r2wd1yfa	459	2	appears	appear	VBZ
cord-015935-r2wd1yfa	459	3	to	to	TO
cord-015935-r2wd1yfa	459	4	be	be	VB
cord-015935-r2wd1yfa	459	5	neurostructural	neurostructural	NNP
cord-015935-r2wd1yfa	459	6	association	association	NNP
cord-015935-r2wd1yfa	459	7	between	between	IN
cord-015935-r2wd1yfa	459	8	SLI	SLI	NNP
cord-015935-r2wd1yfa	459	9	and	and	CC
cord-015935-r2wd1yfa	459	10	autism	autism	NN
cord-015935-r2wd1yfa	460	1	(	(	-LRB-
cord-015935-r2wd1yfa	460	2	Herbert	Herbert	NNP
cord-015935-r2wd1yfa	460	3	et	et	NNP
cord-015935-r2wd1yfa	460	4	al	al	NNP
cord-015935-r2wd1yfa	460	5	.	.	NNP
cord-015935-r2wd1yfa	460	6	,	,	,
cord-015935-r2wd1yfa	460	7	2002	2002	CD
cord-015935-r2wd1yfa	460	8	;	;	:
cord-015935-r2wd1yfa	460	9	2004	2004	CD
cord-015935-r2wd1yfa	460	10	)	)	-RRB-
cord-015935-r2wd1yfa	460	11	,	,	,
cord-015935-r2wd1yfa	460	12	and	and	CC
cord-015935-r2wd1yfa	460	13	there	there	EX
cord-015935-r2wd1yfa	460	14	is	be	VBZ
cord-015935-r2wd1yfa	460	15	an	an	DT
cord-015935-r2wd1yfa	460	16	associated	associate	VBN
cord-015935-r2wd1yfa	460	17	finding	finding	NN
cord-015935-r2wd1yfa	460	18	of	of	IN
cord-015935-r2wd1yfa	460	19	language	language	NN
cord-015935-r2wd1yfa	460	20	delay	delay	NN
cord-015935-r2wd1yfa	460	21	in	in	IN
cord-015935-r2wd1yfa	460	22	relatives	relative	NNS
cord-015935-r2wd1yfa	460	23	of	of	IN
cord-015935-r2wd1yfa	460	24	probands	proband	NNS
cord-015935-r2wd1yfa	460	25	with	with	IN
cord-015935-r2wd1yfa	460	26	autism	autism	NN
cord-015935-r2wd1yfa	461	1	(	(	-LRB-
cord-015935-r2wd1yfa	461	2	Wassink	Wassink	NNP
cord-015935-r2wd1yfa	461	3	et	et	NNP
cord-015935-r2wd1yfa	461	4	al	al	NNP
cord-015935-r2wd1yfa	461	5	.	.	NNP
cord-015935-r2wd1yfa	461	6	,	,	,
cord-015935-r2wd1yfa	461	7	2004	2004	CD
cord-015935-r2wd1yfa	461	8	)	)	-RRB-
cord-015935-r2wd1yfa	461	9	.	.	.
cord-015935-r2wd1yfa	462	1	Several	several	JJ
cord-015935-r2wd1yfa	462	2	investigations	investigation	NNS
cord-015935-r2wd1yfa	462	3	have	have	VBP
cord-015935-r2wd1yfa	462	4	found	find	VBN
cord-015935-r2wd1yfa	462	5	strong	strong	JJ
cord-015935-r2wd1yfa	462	6	linkage	linkage	NN
cord-015935-r2wd1yfa	462	7	of	of	IN
cord-015935-r2wd1yfa	462	8	SLI	SLI	NNP
cord-015935-r2wd1yfa	462	9	to	to	TO
cord-015935-r2wd1yfa	462	10	chromosome	chromosome	NN
cord-015935-r2wd1yfa	463	1	13q21	13q21	CD
cord-015935-r2wd1yfa	464	1	(	(	-LRB-
cord-015935-r2wd1yfa	464	2	Bartlett	Bartlett	NNP
cord-015935-r2wd1yfa	464	3	et	et	NNP
cord-015935-r2wd1yfa	464	4	al	al	NNP
cord-015935-r2wd1yfa	464	5	.	.	NNP
cord-015935-r2wd1yfa	464	6	,	,	,
cord-015935-r2wd1yfa	464	7	2002	2002	CD
cord-015935-r2wd1yfa	464	8	;	;	:
cord-015935-r2wd1yfa	464	9	2004	2004	CD
cord-015935-r2wd1yfa	464	10	)	)	-RRB-
cord-015935-r2wd1yfa	464	11	and	and	CC
cord-015935-r2wd1yfa	464	12	to	to	IN
cord-015935-r2wd1yfa	464	13	chromosomes	chromosome	NNS
cord-015935-r2wd1yfa	464	14	16q	16q	CD
cord-015935-r2wd1yfa	464	15	and	and	CC
cord-015935-r2wd1yfa	464	16	19q	19q	CD
cord-015935-r2wd1yfa	465	1	(	(	-LRB-
cord-015935-r2wd1yfa	465	2	SLI	SLI	NNP
cord-015935-r2wd1yfa	465	3	Consortium	Consortium	NNP
cord-015935-r2wd1yfa	465	4	,	,	,
cord-015935-r2wd1yfa	465	5	2002	2002	CD
cord-015935-r2wd1yfa	465	6	,	,	,
cord-015935-r2wd1yfa	465	7	2004	2004	CD
cord-015935-r2wd1yfa	465	8	.	.	.
cord-015935-r2wd1yfa	466	1	This	this	DT
cord-015935-r2wd1yfa	466	2	finding	finding	NN
cord-015935-r2wd1yfa	466	3	is	be	VBZ
cord-015935-r2wd1yfa	466	4	noteworthy	noteworthy	JJ
cord-015935-r2wd1yfa	466	5	as	as	IN
cord-015935-r2wd1yfa	466	6	it	-PRON-	PRP
cord-015935-r2wd1yfa	466	7	directly	directly	RB
cord-015935-r2wd1yfa	466	8	overlies	overlie	VBZ
cord-015935-r2wd1yfa	466	9	the	the	DT
cord-015935-r2wd1yfa	466	10	16q	16q	CD
cord-015935-r2wd1yfa	466	11	locus	locus	NN
cord-015935-r2wd1yfa	466	12	linked	link	VBN
cord-015935-r2wd1yfa	466	13	to	to	IN
cord-015935-r2wd1yfa	466	14	autism	autism	NN
cord-015935-r2wd1yfa	466	15	(	(	-LRB-
cord-015935-r2wd1yfa	466	16	Wassink	Wassink	NNP
cord-015935-r2wd1yfa	466	17	et	et	NNP
cord-015935-r2wd1yfa	466	18	al	al	NNP
cord-015935-r2wd1yfa	466	19	.	.	NNP
cord-015935-r2wd1yfa	466	20	,	,	,
cord-015935-r2wd1yfa	466	21	2004	2004	CD
cord-015935-r2wd1yfa	466	22	)	)	-RRB-
cord-015935-r2wd1yfa	466	23	.	.	.
cord-015935-r2wd1yfa	467	1	A	a	DT
cord-015935-r2wd1yfa	467	2	specific	specific	JJ
cord-015935-r2wd1yfa	467	3	language	language	NN
cord-015935-r2wd1yfa	467	4	marker	marker	NN
cord-015935-r2wd1yfa	467	5	,	,	,
cord-015935-r2wd1yfa	467	6	age	age	NN
cord-015935-r2wd1yfa	467	7	of	of	IN
cord-015935-r2wd1yfa	467	8	first	first	JJ
cord-015935-r2wd1yfa	467	9	word	word	NN
cord-015935-r2wd1yfa	467	10	,	,	,
cord-015935-r2wd1yfa	467	11	has	have	VBZ
cord-015935-r2wd1yfa	467	12	shown	show	VBN
cord-015935-r2wd1yfa	467	13	significant	significant	JJ
cord-015935-r2wd1yfa	467	14	linkage	linkage	NN
cord-015935-r2wd1yfa	467	15	to	to	IN
cord-015935-r2wd1yfa	467	16	chromosome	chromosome	NN
cord-015935-r2wd1yfa	467	17	7	7	CD
cord-015935-r2wd1yfa	467	18	observed	observe	VBD
cord-015935-r2wd1yfa	467	19	by	by	IN
cord-015935-r2wd1yfa	467	20	five	five	CD
cord-015935-r2wd1yfa	467	21	separate	separate	JJ
cord-015935-r2wd1yfa	467	22	investigators	investigator	NNS
cord-015935-r2wd1yfa	467	23	(	(	-LRB-
cord-015935-r2wd1yfa	467	24	Losh	Losh	NNP
cord-015935-r2wd1yfa	467	25	et	et	NNP
cord-015935-r2wd1yfa	467	26	al	al	NNP
cord-015935-r2wd1yfa	467	27	.	.	NNP
cord-015935-r2wd1yfa	467	28	,	,	,
cord-015935-r2wd1yfa	467	29	2008	2008	CD
cord-015935-r2wd1yfa	467	30	)	)	-RRB-
cord-015935-r2wd1yfa	467	31	.	.	.
cord-015935-r2wd1yfa	468	1	The	the	DT
cord-015935-r2wd1yfa	468	2	7q	7q	CD
cord-015935-r2wd1yfa	468	3	region	region	NN
cord-015935-r2wd1yfa	468	4	has	have	VBZ
cord-015935-r2wd1yfa	468	5	been	be	VBN
cord-015935-r2wd1yfa	468	6	the	the	DT
cord-015935-r2wd1yfa	468	7	subject	subject	NN
cord-015935-r2wd1yfa	468	8	of	of	IN
cord-015935-r2wd1yfa	468	9	intense	intense	JJ
cord-015935-r2wd1yfa	468	10	investigation	investigation	NN
cord-015935-r2wd1yfa	468	11	,	,	,
cord-015935-r2wd1yfa	468	12	as	as	IN
cord-015935-r2wd1yfa	468	13	described	describe	VBN
cord-015935-r2wd1yfa	468	14	above	above	RB
cord-015935-r2wd1yfa	468	15	,	,	,
cord-015935-r2wd1yfa	468	16	and	and	CC
cord-015935-r2wd1yfa	468	17	may	may	MD
cord-015935-r2wd1yfa	468	18	be	be	VB
cord-015935-r2wd1yfa	468	19	the	the	DT
cord-015935-r2wd1yfa	468	20	loci	locus	NNS
cord-015935-r2wd1yfa	468	21	associated	associate	VBN
cord-015935-r2wd1yfa	468	22	with	with	IN
cord-015935-r2wd1yfa	468	23	autism	autism	NN
cord-015935-r2wd1yfa	468	24	language	language	NN
cord-015935-r2wd1yfa	468	25	.	.	.
cord-015935-r2wd1yfa	469	1	The	the	DT
cord-015935-r2wd1yfa	469	2	restricted	restricted	JJ
cord-015935-r2wd1yfa	469	3	and	and	CC
cord-015935-r2wd1yfa	469	4	repetitive	repetitive	JJ
cord-015935-r2wd1yfa	469	5	behavior	behavior	NN
cord-015935-r2wd1yfa	470	1	(	(	-LRB-
cord-015935-r2wd1yfa	470	2	RRB	RRB	NNP
cord-015935-r2wd1yfa	470	3	)	)	-RRB-
cord-015935-r2wd1yfa	470	4	endophenotype	endophenotype	NN
cord-015935-r2wd1yfa	470	5	in	in	IN
cord-015935-r2wd1yfa	470	6	children	child	NNS
cord-015935-r2wd1yfa	470	7	with	with	IN
cord-015935-r2wd1yfa	470	8	autism	autism	NN
cord-015935-r2wd1yfa	470	9	is	be	VBZ
cord-015935-r2wd1yfa	470	10	receiving	receive	VBG
cord-015935-r2wd1yfa	470	11	attention	attention	NN
cord-015935-r2wd1yfa	470	12	(	(	-LRB-
cord-015935-r2wd1yfa	470	13	Morgan	Morgan	NNP
cord-015935-r2wd1yfa	470	14	,	,	,
cord-015935-r2wd1yfa	470	15	Wetherby	Wetherby	NNP
cord-015935-r2wd1yfa	470	16	,	,	,
cord-015935-r2wd1yfa	470	17	&	&	CC
cord-015935-r2wd1yfa	470	18	Barber	Barber	NNP
cord-015935-r2wd1yfa	470	19	,	,	,
cord-015935-r2wd1yfa	470	20	2008	2008	CD
cord-015935-r2wd1yfa	470	21	)	)	-RRB-
cord-015935-r2wd1yfa	470	22	.	.	.
cord-015935-r2wd1yfa	471	1	RRB	RRB	NNP
cord-015935-r2wd1yfa	471	2	comprises	comprise	VBZ
cord-015935-r2wd1yfa	471	3	one	one	CD
cord-015935-r2wd1yfa	471	4	prong	prong	NN
cord-015935-r2wd1yfa	471	5	of	of	IN
cord-015935-r2wd1yfa	471	6	the	the	DT
cord-015935-r2wd1yfa	471	7	autism	autism	NN
cord-015935-r2wd1yfa	471	8	clinical	clinical	JJ
cord-015935-r2wd1yfa	471	9	triad	triad	NNP
cord-015935-r2wd1yfa	471	10	(	(	-LRB-
cord-015935-r2wd1yfa	471	11	language	language	NN
cord-015935-r2wd1yfa	471	12	deficit	deficit	NN
cord-015935-r2wd1yfa	471	13	,	,	,
cord-015935-r2wd1yfa	471	14	social	social	JJ
cord-015935-r2wd1yfa	471	15	deficit	deficit	NN
cord-015935-r2wd1yfa	471	16	,	,	,
cord-015935-r2wd1yfa	471	17	and	and	CC
cord-015935-r2wd1yfa	471	18	RRB	RRB	NNP
cord-015935-r2wd1yfa	471	19	)	)	-RRB-
cord-015935-r2wd1yfa	471	20	.	.	.
cord-015935-r2wd1yfa	472	1	Cuccaro	Cuccaro	NNP
cord-015935-r2wd1yfa	472	2	et	et	NNP
cord-015935-r2wd1yfa	472	3	al	al	NNP
cord-015935-r2wd1yfa	472	4	.	.	.
cord-015935-r2wd1yfa	473	1	(	(	-LRB-
cord-015935-r2wd1yfa	473	2	2003	2003	CD
cord-015935-r2wd1yfa	473	3	)	)	-RRB-
cord-015935-r2wd1yfa	473	4	identified	identify	VBD
cord-015935-r2wd1yfa	473	5	two	two	CD
cord-015935-r2wd1yfa	473	6	factors	factor	NNS
cord-015935-r2wd1yfa	473	7	underlying	underlie	VBG
cord-015935-r2wd1yfa	473	8	RRB	RRB	NNP
cord-015935-r2wd1yfa	473	9	as	as	IN
cord-015935-r2wd1yfa	473	10	measured	measure	VBN
cord-015935-r2wd1yfa	473	11	by	by	IN
cord-015935-r2wd1yfa	473	12	the	the	DT
cord-015935-r2wd1yfa	473	13	Autism	Autism	NNP
cord-015935-r2wd1yfa	473	14	Diagnostic	Diagnostic	NNP
cord-015935-r2wd1yfa	473	15	Interview	Interview	NNP
cord-015935-r2wd1yfa	473	16	-	-	HYPH
cord-015935-r2wd1yfa	473	17	Revised	revise	VBN
cord-015935-r2wd1yfa	473	18	(	(	-LRB-
cord-015935-r2wd1yfa	473	19	ADI	ADI	NNP
cord-015935-r2wd1yfa	473	20	-	-	HYPH
cord-015935-r2wd1yfa	473	21	R	R	NNP
cord-015935-r2wd1yfa	473	22	)	)	-RRB-
cord-015935-r2wd1yfa	473	23	:	:	:
cord-015935-r2wd1yfa	473	24	repetitive	repetitive	JJ
cord-015935-r2wd1yfa	473	25	sensory	sensory	JJ
cord-015935-r2wd1yfa	473	26	motor	motor	NN
cord-015935-r2wd1yfa	473	27	actions	action	NNS
cord-015935-r2wd1yfa	473	28	and	and	CC
cord-015935-r2wd1yfa	473	29	resistance	resistance	NN
cord-015935-r2wd1yfa	473	30	to	to	TO
cord-015935-r2wd1yfa	473	31	change	change	VB
cord-015935-r2wd1yfa	473	32	.	.	.
cord-015935-r2wd1yfa	474	1	This	this	DT
cord-015935-r2wd1yfa	474	2	is	be	VBZ
cord-015935-r2wd1yfa	474	3	of	of	IN
cord-015935-r2wd1yfa	474	4	interest	interest	NN
cord-015935-r2wd1yfa	474	5	as	as	IN
cord-015935-r2wd1yfa	474	6	a	a	DT
cord-015935-r2wd1yfa	474	7	genetic	genetic	JJ
cord-015935-r2wd1yfa	474	8	linkage	linkage	NN
cord-015935-r2wd1yfa	474	9	signal	signal	NN
cord-015935-r2wd1yfa	474	10	has	have	VBZ
cord-015935-r2wd1yfa	474	11	been	be	VBN
cord-015935-r2wd1yfa	474	12	reported	report	VBN
cord-015935-r2wd1yfa	474	13	for	for	IN
cord-015935-r2wd1yfa	474	14	resistance	resistance	NN
cord-015935-r2wd1yfa	474	15	to	to	TO
cord-015935-r2wd1yfa	474	16	change	change	VB
cord-015935-r2wd1yfa	474	17	on	on	IN
cord-015935-r2wd1yfa	474	18	chromosome	chromosome	NN
cord-015935-r2wd1yfa	474	19	15	15	CD
cord-015935-r2wd1yfa	474	20	.	.	.
cord-015935-r2wd1yfa	475	1	It	-PRON-	PRP
cord-015935-r2wd1yfa	475	2	appears	appear	VBZ
cord-015935-r2wd1yfa	475	3	that	that	IN
cord-015935-r2wd1yfa	475	4	the	the	DT
cord-015935-r2wd1yfa	475	5	analysis	analysis	NN
cord-015935-r2wd1yfa	475	6	of	of	IN
cord-015935-r2wd1yfa	475	7	phenotypic	phenotypic	JJ
cord-015935-r2wd1yfa	475	8	homogeneous	homogeneous	JJ
cord-015935-r2wd1yfa	475	9	subtypes	subtype	NNS
cord-015935-r2wd1yfa	475	10	may	may	MD
cord-015935-r2wd1yfa	475	11	be	be	VB
cord-015935-r2wd1yfa	475	12	a	a	DT
cord-015935-r2wd1yfa	475	13	powerful	powerful	JJ
cord-015935-r2wd1yfa	475	14	tool	tool	NN
cord-015935-r2wd1yfa	475	15	for	for	IN
cord-015935-r2wd1yfa	475	16	mapping	mapping	NN
cord-015935-r2wd1yfa	475	17	of	of	IN
cord-015935-r2wd1yfa	475	18	candidate	candidate	NN
cord-015935-r2wd1yfa	475	19	genes	gene	NNS
cord-015935-r2wd1yfa	475	20	in	in	IN
cord-015935-r2wd1yfa	475	21	complex	complex	JJ
cord-015935-r2wd1yfa	475	22	traits	trait	NNS
cord-015935-r2wd1yfa	475	23	such	such	JJ
cord-015935-r2wd1yfa	475	24	as	as	IN
cord-015935-r2wd1yfa	475	25	autism	autism	NN
cord-015935-r2wd1yfa	475	26	.	.	.
cord-015935-r2wd1yfa	476	1	The	the	DT
cord-015935-r2wd1yfa	476	2	recent	recent	JJ
cord-015935-r2wd1yfa	476	3	marked	marked	JJ
cord-015935-r2wd1yfa	476	4	increase	increase	NN
cord-015935-r2wd1yfa	476	5	in	in	IN
cord-015935-r2wd1yfa	476	6	the	the	DT
cord-015935-r2wd1yfa	476	7	incidence	incidence	NN
cord-015935-r2wd1yfa	476	8	and	and	CC
cord-015935-r2wd1yfa	476	9	awareness	awareness	NN
cord-015935-r2wd1yfa	476	10	of	of	IN
cord-015935-r2wd1yfa	476	11	autism	autism	NN
cord-015935-r2wd1yfa	476	12	has	have	VBZ
cord-015935-r2wd1yfa	476	13	resulted	result	VBN
cord-015935-r2wd1yfa	476	14	in	in	IN
cord-015935-r2wd1yfa	476	15	an	an	DT
cord-015935-r2wd1yfa	476	16	increase	increase	NN
cord-015935-r2wd1yfa	476	17	in	in	IN
cord-015935-r2wd1yfa	476	18	the	the	DT
cord-015935-r2wd1yfa	476	19	number	number	NN
cord-015935-r2wd1yfa	476	20	of	of	IN
cord-015935-r2wd1yfa	476	21	children	child	NNS
cord-015935-r2wd1yfa	476	22	sent	send	VBN
cord-015935-r2wd1yfa	476	23	for	for	IN
cord-015935-r2wd1yfa	476	24	diagnostic	diagnostic	JJ
cord-015935-r2wd1yfa	476	25	evaluation	evaluation	NN
cord-015935-r2wd1yfa	476	26	.	.	.
cord-015935-r2wd1yfa	477	1	The	the	DT
cord-015935-r2wd1yfa	477	2	general	general	JJ
cord-015935-r2wd1yfa	477	3	consensus	consensus	NN
cord-015935-r2wd1yfa	477	4	within	within	IN
cord-015935-r2wd1yfa	477	5	the	the	DT
cord-015935-r2wd1yfa	477	6	literature	literature	NN
cord-015935-r2wd1yfa	477	7	is	be	VBZ
cord-015935-r2wd1yfa	477	8	that	that	DT
cord-015935-r2wd1yfa	477	9	genetic	genetic	JJ
cord-015935-r2wd1yfa	477	10	consultation	consultation	NN
cord-015935-r2wd1yfa	477	11	should	should	MD
cord-015935-r2wd1yfa	477	12	be	be	VB
cord-015935-r2wd1yfa	477	13	conducted	conduct	VBN
cord-015935-r2wd1yfa	477	14	on	on	IN
cord-015935-r2wd1yfa	477	15	all	all	DT
cord-015935-r2wd1yfa	477	16	persons	person	NNS
cord-015935-r2wd1yfa	477	17	with	with	IN
cord-015935-r2wd1yfa	477	18	the	the	DT
cord-015935-r2wd1yfa	477	19	confirmed	confirm	VBN
cord-015935-r2wd1yfa	477	20	diagnosis	diagnosis	NN
cord-015935-r2wd1yfa	477	21	of	of	IN
cord-015935-r2wd1yfa	477	22	autism	autism	NN
cord-015935-r2wd1yfa	477	23	.	.	.
cord-015935-r2wd1yfa	478	1	While	while	IN
cord-015935-r2wd1yfa	478	2	referral	referral	NN
cord-015935-r2wd1yfa	478	3	for	for	IN
cord-015935-r2wd1yfa	478	4	genetic	genetic	JJ
cord-015935-r2wd1yfa	478	5	consult	consult	NN
cord-015935-r2wd1yfa	478	6	is	be	VBZ
cord-015935-r2wd1yfa	478	7	often	often	RB
cord-015935-r2wd1yfa	478	8	preferred	prefer	VBN
cord-015935-r2wd1yfa	478	9	,	,	,
cord-015935-r2wd1yfa	478	10	often	often	RB
cord-015935-r2wd1yfa	478	11	the	the	DT
cord-015935-r2wd1yfa	478	12	primary	primary	JJ
cord-015935-r2wd1yfa	478	13	practitioner	practitioner	NN
cord-015935-r2wd1yfa	478	14	,	,	,
cord-015935-r2wd1yfa	478	15	pediatrician	pediatrician	NN
cord-015935-r2wd1yfa	478	16	,	,	,
cord-015935-r2wd1yfa	478	17	and/or	and/or	CC
cord-015935-r2wd1yfa	478	18	pediatric	pediatric	JJ
cord-015935-r2wd1yfa	478	19	neurologist	neurologist	NN
cord-015935-r2wd1yfa	478	20	are	be	VBP
cord-015935-r2wd1yfa	478	21	in	in	IN
cord-015935-r2wd1yfa	478	22	a	a	DT
cord-015935-r2wd1yfa	478	23	position	position	NN
cord-015935-r2wd1yfa	478	24	to	to	TO
cord-015935-r2wd1yfa	478	25	conduct	conduct	VB
cord-015935-r2wd1yfa	478	26	the	the	DT
cord-015935-r2wd1yfa	478	27	initial	initial	JJ
cord-015935-r2wd1yfa	478	28	evaluation	evaluation	NN
cord-015935-r2wd1yfa	478	29	.	.	.
cord-015935-r2wd1yfa	479	1	Further	further	RB
cord-015935-r2wd1yfa	479	2	,	,	,
cord-015935-r2wd1yfa	479	3	clinical	clinical	JJ
cord-015935-r2wd1yfa	479	4	geneticists	geneticist	NNS
cord-015935-r2wd1yfa	479	5	may	may	MD
cord-015935-r2wd1yfa	479	6	not	not	RB
cord-015935-r2wd1yfa	479	7	be	be	VB
cord-015935-r2wd1yfa	479	8	available	available	JJ
cord-015935-r2wd1yfa	479	9	,	,	,
cord-015935-r2wd1yfa	479	10	particularly	particularly	RB
cord-015935-r2wd1yfa	479	11	in	in	IN
cord-015935-r2wd1yfa	479	12	underserved	underserved	JJ
cord-015935-r2wd1yfa	479	13	areas	area	NNS
cord-015935-r2wd1yfa	479	14	of	of	IN
cord-015935-r2wd1yfa	479	15	the	the	DT
cord-015935-r2wd1yfa	479	16	country	country	NN
cord-015935-r2wd1yfa	479	17	,	,	,
cord-015935-r2wd1yfa	479	18	or	or	CC
cord-015935-r2wd1yfa	479	19	a	a	DT
cord-015935-r2wd1yfa	479	20	timely	timely	JJ
cord-015935-r2wd1yfa	479	21	genetic	genetic	JJ
cord-015935-r2wd1yfa	479	22	evaluation	evaluation	NN
cord-015935-r2wd1yfa	479	23	may	may	MD
cord-015935-r2wd1yfa	479	24	not	not	RB
cord-015935-r2wd1yfa	479	25	be	be	VB
cord-015935-r2wd1yfa	479	26	possible	possible	JJ
cord-015935-r2wd1yfa	479	27	due	due	IN
cord-015935-r2wd1yfa	479	28	to	to	IN
cord-015935-r2wd1yfa	479	29	lengthy	lengthy	JJ
cord-015935-r2wd1yfa	479	30	waiting	waiting	NN
cord-015935-r2wd1yfa	479	31	lists	list	NNS
cord-015935-r2wd1yfa	479	32	.	.	.
cord-015935-r2wd1yfa	480	1	Therefore	therefore	RB
cord-015935-r2wd1yfa	480	2	,	,	,
cord-015935-r2wd1yfa	480	3	the	the	DT
cord-015935-r2wd1yfa	480	4	clinician	clinician	NN
cord-015935-r2wd1yfa	480	5	taking	take	VBG
cord-015935-r2wd1yfa	480	6	care	care	NN
cord-015935-r2wd1yfa	480	7	of	of	IN
cord-015935-r2wd1yfa	480	8	a	a	DT
cord-015935-r2wd1yfa	480	9	child	child	NN
cord-015935-r2wd1yfa	480	10	with	with	IN
cord-015935-r2wd1yfa	480	11	autism	autism	NN
cord-015935-r2wd1yfa	480	12	may	may	MD
cord-015935-r2wd1yfa	480	13	wish	wish	VB
cord-015935-r2wd1yfa	480	14	to	to	TO
cord-015935-r2wd1yfa	480	15	initiate	initiate	VB
cord-015935-r2wd1yfa	480	16	the	the	DT
cord-015935-r2wd1yfa	480	17	genetic	genetic	JJ
cord-015935-r2wd1yfa	480	18	evaluation	evaluation	NN
cord-015935-r2wd1yfa	480	19	.	.	.
cord-015935-r2wd1yfa	481	1	Recently	recently	RB
cord-015935-r2wd1yfa	481	2	,	,	,
cord-015935-r2wd1yfa	481	3	sequential	sequential	JJ
cord-015935-r2wd1yfa	481	4	guidelines	guideline	NNS
cord-015935-r2wd1yfa	481	5	for	for	IN
cord-015935-r2wd1yfa	481	6	clinical	clinical	JJ
cord-015935-r2wd1yfa	481	7	genetics	genetics	NN
cord-015935-r2wd1yfa	481	8	evaluation	evaluation	NN
cord-015935-r2wd1yfa	481	9	in	in	IN
cord-015935-r2wd1yfa	481	10	autism	autism	NN
cord-015935-r2wd1yfa	481	11	have	have	VBP
cord-015935-r2wd1yfa	481	12	been	be	VBN
cord-015935-r2wd1yfa	481	13	published	publish	VBN
cord-015935-r2wd1yfa	481	14	by	by	IN
cord-015935-r2wd1yfa	481	15	Schaefer	Schaefer	NNP
cord-015935-r2wd1yfa	481	16	,	,	,
cord-015935-r2wd1yfa	481	17	Mendelsohn	Mendelsohn	NNP
cord-015935-r2wd1yfa	481	18	,	,	,
cord-015935-r2wd1yfa	481	19	and	and	CC
cord-015935-r2wd1yfa	481	20	the	the	DT
cord-015935-r2wd1yfa	481	21	Professional	Professional	NNP
cord-015935-r2wd1yfa	481	22	Practice	Practice	NNP
cord-015935-r2wd1yfa	481	23	and	and	CC
cord-015935-r2wd1yfa	481	24	Guidelines	Guidelines	NNPS
cord-015935-r2wd1yfa	481	25	Committee	Committee	NNP
cord-015935-r2wd1yfa	481	26	(	(	-LRB-
cord-015935-r2wd1yfa	481	27	2008	2008	CD
cord-015935-r2wd1yfa	481	28	)	)	-RRB-
cord-015935-r2wd1yfa	482	1	(	(	-LRB-
cord-015935-r2wd1yfa	482	2	see	see	VB
cord-015935-r2wd1yfa	482	3	Box	Box	NNP
cord-015935-r2wd1yfa	482	4	6.5	6.5	CD
cord-015935-r2wd1yfa	482	5	)	)	-RRB-
cord-015935-r2wd1yfa	482	6	.	.	.
cord-015935-r2wd1yfa	483	1	These	these	DT
cord-015935-r2wd1yfa	483	2	evidence	evidence	NN
cord-015935-r2wd1yfa	483	3	-	-	HYPH
cord-015935-r2wd1yfa	483	4	based	base	VBN
cord-015935-r2wd1yfa	483	5	guidelines	guideline	NNS
cord-015935-r2wd1yfa	483	6	have	have	VBP
cord-015935-r2wd1yfa	483	7	evolved	evolve	VBN
cord-015935-r2wd1yfa	483	8	from	from	IN
cord-015935-r2wd1yfa	483	9	an	an	DT
cord-015935-r2wd1yfa	483	10	original	original	JJ
cord-015935-r2wd1yfa	483	11	retrospective	retrospective	JJ
cord-015935-r2wd1yfa	483	12	study	study	NN
cord-015935-r2wd1yfa	483	13	of	of	IN
cord-015935-r2wd1yfa	483	14	patients	patient	NNS
cord-015935-r2wd1yfa	483	15	referred	refer	VBN
cord-015935-r2wd1yfa	483	16	for	for	IN
cord-015935-r2wd1yfa	483	17	clinical	clinical	JJ
cord-015935-r2wd1yfa	483	18	genetics	genetics	NN
cord-015935-r2wd1yfa	483	19	evaluation	evaluation	NN
cord-015935-r2wd1yfa	483	20	between	between	IN
cord-015935-r2wd1yfa	483	21	the	the	DT
cord-015935-r2wd1yfa	483	22	years	year	NNS
cord-015935-r2wd1yfa	483	23	2002	2002	CD
cord-015935-r2wd1yfa	483	24	and	and	CC
cord-015935-r2wd1yfa	483	25	2004	2004	CD
cord-015935-r2wd1yfa	483	26	at	at	IN
cord-015935-r2wd1yfa	483	27	the	the	DT
cord-015935-r2wd1yfa	483	28	University	University	NNP
cord-015935-r2wd1yfa	483	29	of	of	IN
cord-015935-r2wd1yfa	483	30	Nebraska	Nebraska	NNP
cord-015935-r2wd1yfa	483	31	Medical	Medical	NNP
cord-015935-r2wd1yfa	483	32	Center	Center	NNP
cord-015935-r2wd1yfa	483	33	(	(	-LRB-
cord-015935-r2wd1yfa	483	34	Schaefer	Schaefer	NNP
cord-015935-r2wd1yfa	483	35	&	&	CC
cord-015935-r2wd1yfa	483	36	Lutz	Lutz	NNP
cord-015935-r2wd1yfa	483	37	,	,	,
cord-015935-r2wd1yfa	483	38	2006	2006	CD
cord-015935-r2wd1yfa	483	39	)	)	-RRB-
cord-015935-r2wd1yfa	483	40	.	.	.
cord-015935-r2wd1yfa	484	1	The	the	DT
cord-015935-r2wd1yfa	484	2	guidelines	guideline	NNS
cord-015935-r2wd1yfa	484	3	are	be	VBP
cord-015935-r2wd1yfa	484	4	dynamic	dynamic	JJ
cord-015935-r2wd1yfa	484	5	rather	rather	RB
cord-015935-r2wd1yfa	484	6	than	than	IN
cord-015935-r2wd1yfa	484	7	static	static	JJ
cord-015935-r2wd1yfa	484	8	and	and	CC
cord-015935-r2wd1yfa	484	9	have	have	VBP
cord-015935-r2wd1yfa	484	10	been	be	VBN
cord-015935-r2wd1yfa	484	11	updated	update	VBN
cord-015935-r2wd1yfa	484	12	,	,	,
cord-015935-r2wd1yfa	484	13	for	for	IN
cord-015935-r2wd1yfa	484	14	example	example	NN
cord-015935-r2wd1yfa	484	15	,	,	,
cord-015935-r2wd1yfa	484	16	as	as	IN
cord-015935-r2wd1yfa	484	17	aCGH	aCGH	NNP
cord-015935-r2wd1yfa	484	18	has	have	VBZ
cord-015935-r2wd1yfa	484	19	become	become	VBN
cord-015935-r2wd1yfa	484	20	more	more	RBR
cord-015935-r2wd1yfa	484	21	available	available	JJ
cord-015935-r2wd1yfa	484	22	.	.	.
cord-015935-r2wd1yfa	485	1	The	the	DT
cord-015935-r2wd1yfa	485	2	stepwise	stepwise	JJ
cord-015935-r2wd1yfa	485	3	approach	approach	NN
cord-015935-r2wd1yfa	485	4	was	be	VBD
cord-015935-r2wd1yfa	485	5	designed	design	VBN
cord-015935-r2wd1yfa	485	6	to	to	TO
cord-015935-r2wd1yfa	485	7	balance	balance	VB
cord-015935-r2wd1yfa	485	8	cost	cost	NN
cord-015935-r2wd1yfa	485	9	with	with	IN
cord-015935-r2wd1yfa	485	10	the	the	DT
cord-015935-r2wd1yfa	485	11	expected	expect	VBN
cord-015935-r2wd1yfa	485	12	yield	yield	NN
cord-015935-r2wd1yfa	485	13	of	of	IN
cord-015935-r2wd1yfa	485	14	the	the	DT
cord-015935-r2wd1yfa	485	15	tests	test	NNS
cord-015935-r2wd1yfa	485	16	.	.	.
cord-015935-r2wd1yfa	486	1	Further	further	RB
cord-015935-r2wd1yfa	486	2	,	,	,
cord-015935-r2wd1yfa	486	3	there	there	EX
cord-015935-r2wd1yfa	486	4	is	be	VBZ
cord-015935-r2wd1yfa	486	5	a	a	DT
cord-015935-r2wd1yfa	486	6	pyramidal	pyramidal	JJ
cord-015935-r2wd1yfa	486	7	effect	effect	NN
cord-015935-r2wd1yfa	486	8	so	so	IN
cord-015935-r2wd1yfa	486	9	that	that	IN
cord-015935-r2wd1yfa	486	10	"	"	``
cord-015935-r2wd1yfa	486	11	earlier	early	JJR
cord-015935-r2wd1yfa	486	12	tiers	tier	NNS
cord-015935-r2wd1yfa	486	13	have	have	VBP
cord-015935-r2wd1yfa	486	14	a	a	DT
cord-015935-r2wd1yfa	486	15	greater	great	JJR
cord-015935-r2wd1yfa	486	16	expected	expect	VBN
cord-015935-r2wd1yfa	486	17	diagnostic	diagnostic	JJ
cord-015935-r2wd1yfa	486	18	yield	yield	NN
cord-015935-r2wd1yfa	486	19	,	,	,
cord-015935-r2wd1yfa	486	20	lower	low	JJR
cord-015935-r2wd1yfa	486	21	invasiveness	invasiveness	NN
cord-015935-r2wd1yfa	486	22	of	of	IN
cord-015935-r2wd1yfa	486	23	testing	testing	NN
cord-015935-r2wd1yfa	486	24	,	,	,
cord-015935-r2wd1yfa	486	25	better	well	JJR
cord-015935-r2wd1yfa	486	26	potential	potential	NN
cord-015935-r2wd1yfa	486	27	of	of	IN
cord-015935-r2wd1yfa	486	28	intervention	intervention	NN
cord-015935-r2wd1yfa	486	29	,	,	,
cord-015935-r2wd1yfa	486	30	and	and	CC
cord-015935-r2wd1yfa	486	31	easier	easy	JJR
cord-015935-r2wd1yfa	486	32	overall	overall	JJ
cord-015935-r2wd1yfa	486	33	practicality	practicality	NN
cord-015935-r2wd1yfa	486	34	"	"	''
cord-015935-r2wd1yfa	486	35	.	.	.
cord-015935-r2wd1yfa	487	1	Summarizing	summarize	VBG
cord-015935-r2wd1yfa	487	2	the	the	DT
cord-015935-r2wd1yfa	487	3	diagnostic	diagnostic	JJ
cord-015935-r2wd1yfa	487	4	yields	yield	NNS
cord-015935-r2wd1yfa	487	5	expected	expect	VBN
cord-015935-r2wd1yfa	487	6	for	for	IN
cord-015935-r2wd1yfa	487	7	the	the	DT
cord-015935-r2wd1yfa	487	8	following	follow	VBG
cord-015935-r2wd1yfa	487	9	investigations	investigation	NNS
cord-015935-r2wd1yfa	487	10	(	(	-LRB-
cord-015935-r2wd1yfa	487	11	high	high	JJ
cord-015935-r2wd1yfa	487	12	-	-	HYPH
cord-015935-r2wd1yfa	487	13	resolution	resolution	NN
cord-015935-r2wd1yfa	487	14	chromosome	chromosome	NN
cord-015935-r2wd1yfa	487	15	studies	study	NNS
cord-015935-r2wd1yfa	487	16	,	,	,
cord-015935-r2wd1yfa	487	17	5	5	CD
cord-015935-r2wd1yfa	487	18	%	%	NN
cord-015935-r2wd1yfa	487	19	;	;	,
cord-015935-r2wd1yfa	487	20	aCGH	acgh	LS
cord-015935-r2wd1yfa	487	21	-beyond	-beyond	NN
cord-015935-r2wd1yfa	487	22	that	that	WDT
cord-015935-r2wd1yfa	487	23	detected	detect	VBN
cord-015935-r2wd1yfa	487	24	by	by	IN
cord-015935-r2wd1yfa	487	25	chromosome	chromosome	NN
cord-015935-r2wd1yfa	487	26	analysis	analysis	NN
cord-015935-r2wd1yfa	487	27	-10	-10	NN
cord-015935-r2wd1yfa	487	28	%	%	NN
cord-015935-r2wd1yfa	487	29	;	;	,
cord-015935-r2wd1yfa	487	30	fragile	fragile	JJ
cord-015935-r2wd1yfa	487	31	X	x	NN
cord-015935-r2wd1yfa	487	32	,	,	,
cord-015935-r2wd1yfa	487	33	5	5	CD
cord-015935-r2wd1yfa	487	34	%	%	NN
cord-015935-r2wd1yfa	487	35	;	;	,
cord-015935-r2wd1yfa	487	36	MECP2	mecp2	NN
cord-015935-r2wd1yfa	487	37	,	,	,
cord-015935-r2wd1yfa	487	38	5	5	CD
cord-015935-r2wd1yfa	487	39	%	%	NN
cord-015935-r2wd1yfa	487	40	women	woman	NNS
cord-015935-r2wd1yfa	487	41	only	only	RB
cord-015935-r2wd1yfa	487	42	;	;	:
cord-015935-r2wd1yfa	487	43	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	487	44	,	,	,
cord-015935-r2wd1yfa	487	45	3	3	CD
cord-015935-r2wd1yfa	487	46	%	%	NN
cord-015935-r2wd1yfa	487	47	if	if	IN
cord-015935-r2wd1yfa	487	48	head	head	NN
cord-015935-r2wd1yfa	487	49	circumference	circumference	NN
cord-015935-r2wd1yfa	487	50	>	>	XX
cord-015935-r2wd1yfa	487	51	2.5	2.5	CD
cord-015935-r2wd1yfa	487	52	SD	sd	NN
cord-015935-r2wd1yfa	487	53	;	;	:
cord-015935-r2wd1yfa	487	54	other	other	JJ
cord-015935-r2wd1yfa	487	55	,	,	,
cord-015935-r2wd1yfa	487	56	10	10	CD
cord-015935-r2wd1yfa	487	57	%	%	NN
cord-015935-r2wd1yfa	487	58	)	)	-RRB-
cord-015935-r2wd1yfa	487	59	,	,	,
cord-015935-r2wd1yfa	487	60	it	-PRON-	PRP
cord-015935-r2wd1yfa	487	61	was	be	VBD
cord-015935-r2wd1yfa	487	62	predicted	predict	VBN
cord-015935-r2wd1yfa	487	63	that	that	IN
cord-015935-r2wd1yfa	487	64	utilization	utilization	NN
cord-015935-r2wd1yfa	487	65	of	of	IN
cord-015935-r2wd1yfa	487	66	these	these	DT
cord-015935-r2wd1yfa	487	67	guidelines	guideline	NNS
cord-015935-r2wd1yfa	487	68	would	would	MD
cord-015935-r2wd1yfa	487	69	lead	lead	VB
cord-015935-r2wd1yfa	487	70	to	to	IN
cord-015935-r2wd1yfa	487	71	diagnosis	diagnosis	NN
cord-015935-r2wd1yfa	487	72	in	in	IN
cord-015935-r2wd1yfa	487	73	40	40	CD
cord-015935-r2wd1yfa	487	74	%	%	NN
cord-015935-r2wd1yfa	487	75	of	of	IN
cord-015935-r2wd1yfa	487	76	cases	case	NNS
cord-015935-r2wd1yfa	487	77	(	(	-LRB-
cord-015935-r2wd1yfa	487	78	Schaefer	Schaefer	NNP
cord-015935-r2wd1yfa	487	79	,	,	,
cord-015935-r2wd1yfa	487	80	Mendelsohn	Mendelsohn	NNP
cord-015935-r2wd1yfa	487	81	,	,	,
cord-015935-r2wd1yfa	487	82	and	and	CC
cord-015935-r2wd1yfa	487	83	the	the	DT
cord-015935-r2wd1yfa	487	84	Professional	Professional	NNP
cord-015935-r2wd1yfa	487	85	Practice	Practice	NNP
cord-015935-r2wd1yfa	487	86	and	and	CC
cord-015935-r2wd1yfa	487	87	Guidelines	Guidelines	NNPS
cord-015935-r2wd1yfa	487	88	Committee	Committee	NNP
cord-015935-r2wd1yfa	487	89	(	(	-LRB-
cord-015935-r2wd1yfa	487	90	2008	2008	CD
cord-015935-r2wd1yfa	487	91	)	)	-RRB-
cord-015935-r2wd1yfa	487	92	.	.	.
cord-015935-r2wd1yfa	488	1	Finally	finally	RB
cord-015935-r2wd1yfa	488	2	,	,	,
cord-015935-r2wd1yfa	488	3	this	this	DT
cord-015935-r2wd1yfa	488	4	stepwise	stepwise	JJ
cord-015935-r2wd1yfa	488	5	approach	approach	NN
cord-015935-r2wd1yfa	488	6	has	have	VBZ
cord-015935-r2wd1yfa	488	7	met	meet	VBN
cord-015935-r2wd1yfa	488	8	the	the	DT
cord-015935-r2wd1yfa	488	9	approval	approval	NN
cord-015935-r2wd1yfa	488	10	of	of	IN
cord-015935-r2wd1yfa	488	11	third	third	JJ
cord-015935-r2wd1yfa	488	12	-	-	HYPH
cord-015935-r2wd1yfa	488	13	party	party	NN
cord-015935-r2wd1yfa	488	14	payers	payer	NNS
cord-015935-r2wd1yfa	488	15	and	and	CC
cord-015935-r2wd1yfa	488	16	families	family	NNS
cord-015935-r2wd1yfa	488	17	(	(	-LRB-
cord-015935-r2wd1yfa	488	18	Schaefer	Schaefer	NNP
cord-015935-r2wd1yfa	488	19	&	&	CC
cord-015935-r2wd1yfa	488	20	Lutz	Lutz	NNP
cord-015935-r2wd1yfa	488	21	,	,	,
cord-015935-r2wd1yfa	488	22	2006	2006	CD
cord-015935-r2wd1yfa	488	23	)	)	-RRB-
cord-015935-r2wd1yfa	488	24	.	.	.
cord-015935-r2wd1yfa	489	1	Confirmation	confirmation	NN
cord-015935-r2wd1yfa	489	2	of	of	IN
cord-015935-r2wd1yfa	489	3	diagnosis	diagnosis	NN
cord-015935-r2wd1yfa	489	4	of	of	IN
cord-015935-r2wd1yfa	489	5	autism	autism	NN
cord-015935-r2wd1yfa	489	6	by	by	IN
cord-015935-r2wd1yfa	489	7	trained	train	VBN
cord-015935-r2wd1yfa	489	8	professional	professional	JJ
cord-015935-r2wd1yfa	489	9	using	use	VBG
cord-015935-r2wd1yfa	489	10	objective	objective	JJ
cord-015935-r2wd1yfa	489	11	criteria	criterion	NNS
cord-015935-r2wd1yfa	489	12	and	and	CC
cord-015935-r2wd1yfa	489	13	tools	tool	NNS
cord-015935-r2wd1yfa	489	14	Sensory	sensory	JJ
cord-015935-r2wd1yfa	489	15	screening	screening	NN
cord-015935-r2wd1yfa	489	16	(	(	-LRB-
cord-015935-r2wd1yfa	489	17	 	 	_SP
cord-015935-r2wd1yfa	490	1	This	this	DT
cord-015935-r2wd1yfa	490	2	initial	initial	JJ
cord-015935-r2wd1yfa	490	3	step	step	NN
cord-015935-r2wd1yfa	490	4	includes	include	VBZ
cord-015935-r2wd1yfa	490	5	confirming	confirm	VBG
cord-015935-r2wd1yfa	490	6	the	the	DT
cord-015935-r2wd1yfa	490	7	diagnosis	diagnosis	NN
cord-015935-r2wd1yfa	490	8	of	of	IN
cord-015935-r2wd1yfa	490	9	autism	autism	NN
cord-015935-r2wd1yfa	490	10	using	use	VBG
cord-015935-r2wd1yfa	490	11	objective	objective	JJ
cord-015935-r2wd1yfa	490	12	(	(	-LRB-
cord-015935-r2wd1yfa	490	13	DSM	DSM	NNP
cord-015935-r2wd1yfa	490	14	-	-	HYPH
cord-015935-r2wd1yfa	490	15	IV	IV	NNP
cord-015935-r2wd1yfa	490	16	)	)	-RRB-
cord-015935-r2wd1yfa	490	17	criteria	criterion	NNS
cord-015935-r2wd1yfa	491	1	and/or	and/or	CC
cord-015935-r2wd1yfa	491	2	standardized	standardized	JJ
cord-015935-r2wd1yfa	491	3	objective	objective	JJ
cord-015935-r2wd1yfa	491	4	measures	measure	NNS
cord-015935-r2wd1yfa	491	5	such	such	JJ
cord-015935-r2wd1yfa	491	6	as	as	IN
cord-015935-r2wd1yfa	491	7	those	those	DT
cord-015935-r2wd1yfa	491	8	discussed	discuss	VBN
cord-015935-r2wd1yfa	491	9	in	in	IN
cord-015935-r2wd1yfa	491	10	Chapter	chapter	NN
cord-015935-r2wd1yfa	491	11	15	15	CD
cord-015935-r2wd1yfa	491	12	.	.	.
cord-015935-r2wd1yfa	492	1	An	an	DT
cord-015935-r2wd1yfa	492	2	audiogram	audiogram	NN
cord-015935-r2wd1yfa	492	3	is	be	VBZ
cord-015935-r2wd1yfa	492	4	obtained	obtain	VBN
cord-015935-r2wd1yfa	492	5	to	to	TO
cord-015935-r2wd1yfa	492	6	rule	rule	VB
cord-015935-r2wd1yfa	492	7	out	out	RP
cord-015935-r2wd1yfa	492	8	hearing	hear	VBG
cord-015935-r2wd1yfa	492	9	loss	loss	NN
cord-015935-r2wd1yfa	492	10	and	and	CC
cord-015935-r2wd1yfa	492	11	an	an	DT
cord-015935-r2wd1yfa	492	12	electroencephalogram	electroencephalogram	NN
cord-015935-r2wd1yfa	492	13	(	(	-LRB-
cord-015935-r2wd1yfa	492	14	EEG	EEG	NNP
cord-015935-r2wd1yfa	492	15	)	)	-RRB-
cord-015935-r2wd1yfa	492	16	is	be	VBZ
cord-015935-r2wd1yfa	492	17	obtained	obtain	VBN
cord-015935-r2wd1yfa	492	18	if	if	IN
cord-015935-r2wd1yfa	492	19	there	there	EX
cord-015935-r2wd1yfa	492	20	is	be	VBZ
cord-015935-r2wd1yfa	492	21	a	a	DT
cord-015935-r2wd1yfa	492	22	clinical	clinical	JJ
cord-015935-r2wd1yfa	492	23	suspicion	suspicion	NN
cord-015935-r2wd1yfa	492	24	of	of	IN
cord-015935-r2wd1yfa	492	25	seizures	seizure	NNS
cord-015935-r2wd1yfa	492	26	.	.	.
cord-015935-r2wd1yfa	493	1	Cognitive	cognitive	JJ
cord-015935-r2wd1yfa	493	2	testing	testing	NN
cord-015935-r2wd1yfa	493	3	,	,	,
cord-015935-r2wd1yfa	493	4	when	when	WRB
cord-015935-r2wd1yfa	493	5	appropriate	appropriate	JJ
cord-015935-r2wd1yfa	493	6	,	,	,
cord-015935-r2wd1yfa	493	7	can	can	MD
cord-015935-r2wd1yfa	493	8	determine	determine	VB
cord-015935-r2wd1yfa	493	9	mental	mental	JJ
cord-015935-r2wd1yfa	493	10	retardation	retardation	NN
cord-015935-r2wd1yfa	493	11	.	.	.
cord-015935-r2wd1yfa	494	1	Finally	finally	RB
cord-015935-r2wd1yfa	494	2	,	,	,
cord-015935-r2wd1yfa	494	3	verifying	verify	VBG
cord-015935-r2wd1yfa	494	4	the	the	DT
cord-015935-r2wd1yfa	494	5	results	result	NNS
cord-015935-r2wd1yfa	494	6	of	of	IN
cord-015935-r2wd1yfa	494	7	the	the	DT
cord-015935-r2wd1yfa	494	8	newborn	newborn	JJ
cord-015935-r2wd1yfa	494	9	screen	screen	NN
cord-015935-r2wd1yfa	494	10	can	can	MD
cord-015935-r2wd1yfa	494	11	help	help	VB
cord-015935-r2wd1yfa	494	12	rule	rule	VB
cord-015935-r2wd1yfa	494	13	out	out	RP
cord-015935-r2wd1yfa	494	14	rubella	rubella	NN
cord-015935-r2wd1yfa	494	15	and	and	CC
cord-015935-r2wd1yfa	494	16	PKU	PKU	NNP
cord-015935-r2wd1yfa	494	17	.	.	.
cord-015935-r2wd1yfa	495	1	Initial	initial	JJ
cord-015935-r2wd1yfa	495	2	assessment	assessment	NN
cord-015935-r2wd1yfa	495	3	involves	involve	VBZ
cord-015935-r2wd1yfa	495	4	a	a	DT
cord-015935-r2wd1yfa	495	5	standard	standard	JJ
cord-015935-r2wd1yfa	495	6	clinical	clinical	JJ
cord-015935-r2wd1yfa	495	7	genetic	genetic	JJ
cord-015935-r2wd1yfa	495	8	history	history	NN
cord-015935-r2wd1yfa	495	9	and	and	CC
cord-015935-r2wd1yfa	495	10	physical	physical	JJ
cord-015935-r2wd1yfa	495	11	exam	exam	NN
cord-015935-r2wd1yfa	495	12	to	to	TO
cord-015935-r2wd1yfa	495	13	identify	identify	VB
cord-015935-r2wd1yfa	495	14	known	know	VBN
cord-015935-r2wd1yfa	495	15	syndromes	syndrome	NNS
cord-015935-r2wd1yfa	495	16	or	or	CC
cord-015935-r2wd1yfa	495	17	associated	associate	VBN
cord-015935-r2wd1yfa	495	18	conditions	condition	NNS
cord-015935-r2wd1yfa	495	19	.	.	.
cord-015935-r2wd1yfa	496	1	Included	include	VBN
cord-015935-r2wd1yfa	496	2	would	would	MD
cord-015935-r2wd1yfa	496	3	be	be	VB
cord-015935-r2wd1yfa	496	4	a	a	DT
cord-015935-r2wd1yfa	496	5	Wood	Wood	NNP
cord-015935-r2wd1yfa	496	6	's	's	POS
cord-015935-r2wd1yfa	496	7	lamp	lamp	NN
cord-015935-r2wd1yfa	496	8	examination	examination	NN
cord-015935-r2wd1yfa	496	9	of	of	IN
cord-015935-r2wd1yfa	496	10	the	the	DT
cord-015935-r2wd1yfa	496	11	skin	skin	NN
cord-015935-r2wd1yfa	496	12	to	to	TO
cord-015935-r2wd1yfa	496	13	help	help	VB
cord-015935-r2wd1yfa	496	14	rule	rule	VB
cord-015935-r2wd1yfa	496	15	out	out	RP
cord-015935-r2wd1yfa	496	16	neurocutaneous	neurocutaneous	JJ
cord-015935-r2wd1yfa	496	17	conditions	condition	NNS
cord-015935-r2wd1yfa	496	18	such	such	JJ
cord-015935-r2wd1yfa	496	19	as	as	IN
cord-015935-r2wd1yfa	496	20	TSC	TSC	NNP
cord-015935-r2wd1yfa	496	21	.	.	.
cord-015935-r2wd1yfa	497	1	Also	also	RB
cord-015935-r2wd1yfa	497	2	,	,	,
cord-015935-r2wd1yfa	497	3	for	for	IN
cord-015935-r2wd1yfa	497	4	suspected	suspect	VBN
cord-015935-r2wd1yfa	497	5	diagnoses	diagnosis	NNS
cord-015935-r2wd1yfa	497	6	,	,	,
cord-015935-r2wd1yfa	497	7	standard	standard	JJ
cord-015935-r2wd1yfa	497	8	metabolic	metabolic	JJ
cord-015935-r2wd1yfa	497	9	screening	screening	NN
cord-015935-r2wd1yfa	497	10	is	be	VBZ
cord-015935-r2wd1yfa	497	11	performed	perform	VBN
cord-015935-r2wd1yfa	497	12	to	to	TO
cord-015935-r2wd1yfa	497	13	check	check	VB
cord-015935-r2wd1yfa	497	14	for	for	IN
cord-015935-r2wd1yfa	497	15	urine	urine	NN
cord-015935-r2wd1yfa	497	16	mucopolysaccharides	mucopolysaccharide	NNS
cord-015935-r2wd1yfa	497	17	and	and	CC
cord-015935-r2wd1yfa	497	18	organic	organic	JJ
cord-015935-r2wd1yfa	497	19	acids	acid	NNS
cord-015935-r2wd1yfa	497	20	as	as	RB
cord-015935-r2wd1yfa	497	21	well	well	RB
cord-015935-r2wd1yfa	497	22	as	as	IN
cord-015935-r2wd1yfa	497	23	serum	serum	NN
cord-015935-r2wd1yfa	497	24	lactate	lactate	NN
cord-015935-r2wd1yfa	497	25	,	,	,
cord-015935-r2wd1yfa	497	26	amino	amino	NN
cord-015935-r2wd1yfa	497	27	acid	acid	NN
cord-015935-r2wd1yfa	497	28	,	,	,
cord-015935-r2wd1yfa	497	29	ammonia	ammonia	NN
cord-015935-r2wd1yfa	497	30	,	,	,
cord-015935-r2wd1yfa	497	31	and	and	CC
cord-015935-r2wd1yfa	497	32	acylcarnitine	acylcarnitine	NNP
cord-015935-r2wd1yfa	497	33	profile	profile	NNP
cord-015935-r2wd1yfa	497	34	.	.	.
cord-015935-r2wd1yfa	498	1	If	if	IN
cord-015935-r2wd1yfa	498	2	not	not	RB
cord-015935-r2wd1yfa	498	3	already	already	RB
cord-015935-r2wd1yfa	498	4	performed	perform	VBN
cord-015935-r2wd1yfa	498	5	,	,	,
cord-015935-r2wd1yfa	498	6	high	high	JJ
cord-015935-r2wd1yfa	498	7	-	-	HYPH
cord-015935-r2wd1yfa	498	8	resolution	resolution	NN
cord-015935-r2wd1yfa	498	9	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	498	10	analysis	analysis	NN
cord-015935-r2wd1yfa	498	11	and	and	CC
cord-015935-r2wd1yfa	498	12	DNA	dna	NN
cord-015935-r2wd1yfa	498	13	for	for	IN
cord-015935-r2wd1yfa	498	14	fragile	fragile	JJ
cord-015935-r2wd1yfa	498	15	X	x	NN
cord-015935-r2wd1yfa	498	16	is	be	VBZ
cord-015935-r2wd1yfa	498	17	sent	send	VBN
cord-015935-r2wd1yfa	498	18	.	.	.
cord-015935-r2wd1yfa	499	1	If	if	IN
cord-015935-r2wd1yfa	499	2	the	the	DT
cord-015935-r2wd1yfa	499	3	studies	study	NNS
cord-015935-r2wd1yfa	499	4	in	in	IN
cord-015935-r2wd1yfa	499	5	the	the	DT
cord-015935-r2wd1yfa	499	6	first	first	JJ
cord-015935-r2wd1yfa	499	7	tier	tier	NN
cord-015935-r2wd1yfa	499	8	are	be	VBP
cord-015935-r2wd1yfa	499	9	unrevealing	unrevealing	JJ
cord-015935-r2wd1yfa	499	10	,	,	,
cord-015935-r2wd1yfa	499	11	the	the	DT
cord-015935-r2wd1yfa	499	12	second	second	JJ
cord-015935-r2wd1yfa	499	13	tier	tier	NN
cord-015935-r2wd1yfa	499	14	checks	check	NNS
cord-015935-r2wd1yfa	499	15	for	for	IN
cord-015935-r2wd1yfa	499	16	aCGH	acgh	JJ
cord-015935-r2wd1yfa	499	17	duplications	duplication	NNS
cord-015935-r2wd1yfa	499	18	and	and	CC
cord-015935-r2wd1yfa	499	19	deletions	deletion	NNS
cord-015935-r2wd1yfa	499	20	.	.	.
cord-015935-r2wd1yfa	500	1	For	for	IN
cord-015935-r2wd1yfa	500	2	patients	patient	NNS
cord-015935-r2wd1yfa	500	3	with	with	IN
cord-015935-r2wd1yfa	500	4	pigmentary	pigmentary	JJ
cord-015935-r2wd1yfa	500	5	abnormalities	abnormality	NNS
cord-015935-r2wd1yfa	500	6	on	on	IN
cord-015935-r2wd1yfa	500	7	exam	exam	NN
cord-015935-r2wd1yfa	500	8	but	but	CC
cord-015935-r2wd1yfa	500	9	with	with	IN
cord-015935-r2wd1yfa	500	10	a	a	DT
cord-015935-r2wd1yfa	500	11	normal	normal	JJ
cord-015935-r2wd1yfa	500	12	leukocyte	leukocyte	NN
cord-015935-r2wd1yfa	500	13	karyotype	karyotype	NN
cord-015935-r2wd1yfa	500	14	,	,	,
cord-015935-r2wd1yfa	500	15	skin	skin	NN
cord-015935-r2wd1yfa	500	16	biopsy	biopsy	NN
cord-015935-r2wd1yfa	500	17	can	can	MD
cord-015935-r2wd1yfa	500	18	be	be	VB
cord-015935-r2wd1yfa	500	19	obtained	obtain	VBN
cord-015935-r2wd1yfa	500	20	to	to	TO
cord-015935-r2wd1yfa	500	21	obtain	obtain	VB
cord-015935-r2wd1yfa	500	22	a	a	DT
cord-015935-r2wd1yfa	500	23	fibroblast	fibroblast	NN
cord-015935-r2wd1yfa	500	24	karyotype	karyotype	NN
cord-015935-r2wd1yfa	500	25	.	.	.
cord-015935-r2wd1yfa	501	1	For	for	IN
cord-015935-r2wd1yfa	501	2	females	female	NNS
cord-015935-r2wd1yfa	501	3	,	,	,
cord-015935-r2wd1yfa	501	4	MECP2	mecp2	NN
cord-015935-r2wd1yfa	501	5	gene	gene	NN
cord-015935-r2wd1yfa	501	6	testing	testing	NN
cord-015935-r2wd1yfa	501	7	is	be	VBZ
cord-015935-r2wd1yfa	501	8	obtained	obtain	VBN
cord-015935-r2wd1yfa	501	9	;	;	:
cord-015935-r2wd1yfa	501	10	for	for	IN
cord-015935-r2wd1yfa	501	11	children	child	NNS
cord-015935-r2wd1yfa	501	12	with	with	IN
cord-015935-r2wd1yfa	501	13	head	head	NN
cord-015935-r2wd1yfa	501	14	circumference	circumference	NN
cord-015935-r2wd1yfa	501	15	greater	great	JJR
cord-015935-r2wd1yfa	501	16	than	than	IN
cord-015935-r2wd1yfa	501	17	2.5	2.5	CD
cord-015935-r2wd1yfa	501	18	SD	sd	NN
cord-015935-r2wd1yfa	501	19	from	from	IN
cord-015935-r2wd1yfa	501	20	the	the	DT
cord-015935-r2wd1yfa	501	21	mean	mean	NN
cord-015935-r2wd1yfa	501	22	,	,	,
cord-015935-r2wd1yfa	501	23	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	501	24	gene	gene	NN
cord-015935-r2wd1yfa	501	25	testing	testing	NN
cord-015935-r2wd1yfa	501	26	is	be	VBZ
cord-015935-r2wd1yfa	501	27	recommended	recommend	VBN
cord-015935-r2wd1yfa	501	28	.	.	.
cord-015935-r2wd1yfa	502	1	Lower	low	JJR
cord-015935-r2wd1yfa	502	2	yield	yield	NN
cord-015935-r2wd1yfa	502	3	tests	test	NNS
cord-015935-r2wd1yfa	502	4	have	have	VBP
cord-015935-r2wd1yfa	502	5	been	be	VBN
cord-015935-r2wd1yfa	502	6	reserved	reserve	VBN
cord-015935-r2wd1yfa	502	7	for	for	IN
cord-015935-r2wd1yfa	502	8	this	this	DT
cord-015935-r2wd1yfa	502	9	level	level	NN
cord-015935-r2wd1yfa	502	10	:	:	:
cord-015935-r2wd1yfa	502	11	brain	brain	NN
cord-015935-r2wd1yfa	502	12	magnetic	magnetic	JJ
cord-015935-r2wd1yfa	502	13	resonance	resonance	NN
cord-015935-r2wd1yfa	502	14	imaging	imaging	NN
cord-015935-r2wd1yfa	502	15	and	and	CC
cord-015935-r2wd1yfa	502	16	serum	serum	NN
cord-015935-r2wd1yfa	502	17	and	and	CC
cord-015935-r2wd1yfa	502	18	urine	urine	NN
cord-015935-r2wd1yfa	502	19	uric	uric	NN
cord-015935-r2wd1yfa	502	20	acid	acid	NN
cord-015935-r2wd1yfa	502	21	.	.	.
cord-015935-r2wd1yfa	503	1	Further	further	JJ
cord-015935-r2wd1yfa	503	2	tests	test	NNS
cord-015935-r2wd1yfa	503	3	are	be	VBP
cord-015935-r2wd1yfa	503	4	outlined	outline	VBN
cord-015935-r2wd1yfa	503	5	depending	depend	VBG
cord-015935-r2wd1yfa	503	6	on	on	IN
cord-015935-r2wd1yfa	503	7	the	the	DT
cord-015935-r2wd1yfa	503	8	results	result	NNS
cord-015935-r2wd1yfa	503	9	(	(	-LRB-
cord-015935-r2wd1yfa	503	10	high	high	JJ
cord-015935-r2wd1yfa	503	11	or	or	CC
cord-015935-r2wd1yfa	503	12	low	low	JJ
cord-015935-r2wd1yfa	503	13	)	)	-RRB-
cord-015935-r2wd1yfa	503	14	of	of	IN
cord-015935-r2wd1yfa	503	15	the	the	DT
cord-015935-r2wd1yfa	503	16	uric	uric	JJ
cord-015935-r2wd1yfa	503	17	acid	acid	NN
cord-015935-r2wd1yfa	503	18	tests	test	NNS
cord-015935-r2wd1yfa	503	19	.	.	.
cord-015935-r2wd1yfa	504	1	We	-PRON-	PRP
cord-015935-r2wd1yfa	504	2	would	would	MD
cord-015935-r2wd1yfa	504	3	add	add	VB
cord-015935-r2wd1yfa	504	4	here	here	RB
cord-015935-r2wd1yfa	504	5	that	that	IN
cord-015935-r2wd1yfa	504	6	if	if	IN
cord-015935-r2wd1yfa	504	7	a	a	DT
cord-015935-r2wd1yfa	504	8	child	child	NN
cord-015935-r2wd1yfa	504	9	has	have	VBZ
cord-015935-r2wd1yfa	504	10	significant	significant	JJ
cord-015935-r2wd1yfa	504	11	language	language	NN
cord-015935-r2wd1yfa	504	12	impairment	impairment	NN
cord-015935-r2wd1yfa	504	13	,	,	,
cord-015935-r2wd1yfa	504	14	a	a	DT
cord-015935-r2wd1yfa	504	15	Shank3	Shank3	NNP
cord-015935-r2wd1yfa	504	16	mutation	mutation	NN
cord-015935-r2wd1yfa	504	17	should	should	MD
cord-015935-r2wd1yfa	504	18	be	be	VB
cord-015935-r2wd1yfa	504	19	ruled	rule	VBN
cord-015935-r2wd1yfa	504	20	out	out	RP
cord-015935-r2wd1yfa	504	21	.	.	.
cord-015935-r2wd1yfa	505	1	Finally	finally	RB
cord-015935-r2wd1yfa	505	2	,	,	,
cord-015935-r2wd1yfa	505	3	new	new	JJ
cord-015935-r2wd1yfa	505	4	susceptibility	susceptibility	NN
cord-015935-r2wd1yfa	505	5	loci	locus	NNS
cord-015935-r2wd1yfa	505	6	that	that	WDT
cord-015935-r2wd1yfa	505	7	can	can	MD
cord-015935-r2wd1yfa	505	8	contribute	contribute	VB
cord-015935-r2wd1yfa	505	9	to	to	IN
cord-015935-r2wd1yfa	505	10	the	the	DT
cord-015935-r2wd1yfa	505	11	autism	autism	NN
cord-015935-r2wd1yfa	505	12	phenotype	phenotype	NN
cord-015935-r2wd1yfa	505	13	are	be	VBP
cord-015935-r2wd1yfa	505	14	continually	continually	RB
cord-015935-r2wd1yfa	505	15	identified	identify	VBN
cord-015935-r2wd1yfa	505	16	and	and	CC
cord-015935-r2wd1yfa	505	17	catalogued	catalogue	VBN
cord-015935-r2wd1yfa	505	18	in	in	IN
cord-015935-r2wd1yfa	505	19	the	the	DT
cord-015935-r2wd1yfa	505	20	Online	Online	NNP
cord-015935-r2wd1yfa	505	21	Mendelian	Mendelian	NNP
cord-015935-r2wd1yfa	505	22	Inheritance	Inheritance	NNP
cord-015935-r2wd1yfa	505	23	in	in	IN
cord-015935-r2wd1yfa	505	24	Man	Man	NNP
cord-015935-r2wd1yfa	505	25	(	(	-LRB-
cord-015935-r2wd1yfa	505	26	OMIM	OMIM	NNP
cord-015935-r2wd1yfa	505	27	)	)	-RRB-
cord-015935-r2wd1yfa	505	28	database	database	NN
cord-015935-r2wd1yfa	505	29	(	(	-LRB-
cord-015935-r2wd1yfa	505	30	http//www.ncbi.nlm.nih.gov	http//www.ncbi.nlm.nih.gov	NN
cord-015935-r2wd1yfa	505	31	/	/	SYM
cord-015935-r2wd1yfa	505	32	sites	site	NNS
cord-015935-r2wd1yfa	505	33	/	/	SYM
cord-015935-r2wd1yfa	505	34	entrez	entrez	NNP
cord-015935-r2wd1yfa	505	35	)	)	-RRB-
cord-015935-r2wd1yfa	505	36	.	.	.
cord-015935-r2wd1yfa	506	1	Using	use	VBG
cord-015935-r2wd1yfa	506	2	this	this	DT
cord-015935-r2wd1yfa	506	3	search	search	NN
cord-015935-r2wd1yfa	506	4	engine	engine	NN
cord-015935-r2wd1yfa	506	5	,	,	,
cord-015935-r2wd1yfa	506	6	a	a	DT
cord-015935-r2wd1yfa	506	7	patient	patient	NN
cord-015935-r2wd1yfa	506	8	's	's	POS
cord-015935-r2wd1yfa	506	9	phenotype	phenotype	NN
cord-015935-r2wd1yfa	506	10	including	include	VBG
cord-015935-r2wd1yfa	506	11	dysmorphic	dysmorphic	JJ
cord-015935-r2wd1yfa	506	12	features	feature	NNS
cord-015935-r2wd1yfa	506	13	can	can	MD
cord-015935-r2wd1yfa	506	14	be	be	VB
cord-015935-r2wd1yfa	506	15	entered	enter	VBN
cord-015935-r2wd1yfa	506	16	into	into	IN
cord-015935-r2wd1yfa	506	17	the	the	DT
cord-015935-r2wd1yfa	506	18	program	program	NN
cord-015935-r2wd1yfa	506	19	to	to	TO
cord-015935-r2wd1yfa	506	20	generate	generate	VB
cord-015935-r2wd1yfa	506	21	a	a	DT
cord-015935-r2wd1yfa	506	22	list	list	NN
cord-015935-r2wd1yfa	506	23	of	of	IN
cord-015935-r2wd1yfa	506	24	possible	possible	JJ
cord-015935-r2wd1yfa	506	25	genetic	genetic	JJ
cord-015935-r2wd1yfa	506	26	diagnoses	diagnosis	NNS
cord-015935-r2wd1yfa	506	27	.	.	.
cord-015935-r2wd1yfa	507	1	Most	Most	JJS
cord-015935-r2wd1yfa	507	2	clinical	clinical	JJ
cord-015935-r2wd1yfa	507	3	geneticists	geneticist	NNS
cord-015935-r2wd1yfa	507	4	work	work	VBP
cord-015935-r2wd1yfa	507	5	with	with	IN
cord-015935-r2wd1yfa	507	6	genetic	genetic	JJ
cord-015935-r2wd1yfa	507	7	counselors	counselor	NNS
cord-015935-r2wd1yfa	507	8	who	who	WP
cord-015935-r2wd1yfa	507	9	interpret	interpret	VBP
cord-015935-r2wd1yfa	507	10	the	the	DT
cord-015935-r2wd1yfa	507	11	findings	finding	NNS
cord-015935-r2wd1yfa	507	12	into	into	IN
cord-015935-r2wd1yfa	507	13	recurrent	recurrent	JJ
cord-015935-r2wd1yfa	507	14	risks	risk	NNS
cord-015935-r2wd1yfa	507	15	for	for	IN
cord-015935-r2wd1yfa	507	16	full	full	JJ
cord-015935-r2wd1yfa	507	17	siblings	sibling	NNS
cord-015935-r2wd1yfa	507	18	.	.	.
cord-015935-r2wd1yfa	508	1	The	the	DT
cord-015935-r2wd1yfa	508	2	tiered	tiered	JJ
cord-015935-r2wd1yfa	508	3	clinical	clinical	JJ
cord-015935-r2wd1yfa	508	4	genetics	genetics	NN
cord-015935-r2wd1yfa	508	5	evaluation	evaluation	NN
cord-015935-r2wd1yfa	508	6	should	should	MD
cord-015935-r2wd1yfa	508	7	identify	identify	VB
cord-015935-r2wd1yfa	508	8	two	two	CD
cord-015935-r2wd1yfa	508	9	groups	group	NNS
cord-015935-r2wd1yfa	508	10	of	of	IN
cord-015935-r2wd1yfa	508	11	individuals	individual	NNS
cord-015935-r2wd1yfa	508	12	:	:	:
cord-015935-r2wd1yfa	508	13	those	those	DT
cord-015935-r2wd1yfa	508	14	with	with	IN
cord-015935-r2wd1yfa	508	15	and	and	CC
cord-015935-r2wd1yfa	508	16	those	those	DT
cord-015935-r2wd1yfa	508	17	without	without	IN
cord-015935-r2wd1yfa	508	18	an	an	DT
cord-015935-r2wd1yfa	508	19	identifiable	identifiable	JJ
cord-015935-r2wd1yfa	508	20	etiology	etiology	NN
cord-015935-r2wd1yfa	508	21	for	for	IN
cord-015935-r2wd1yfa	508	22	autism	autism	NN
cord-015935-r2wd1yfa	508	23	.	.	.
cord-015935-r2wd1yfa	509	1	For	for	IN
cord-015935-r2wd1yfa	509	2	those	those	DT
cord-015935-r2wd1yfa	509	3	without	without	IN
cord-015935-r2wd1yfa	509	4	an	an	DT
cord-015935-r2wd1yfa	509	5	identifiable	identifiable	JJ
cord-015935-r2wd1yfa	509	6	etiology	etiology	NN
cord-015935-r2wd1yfa	509	7	,	,	,
cord-015935-r2wd1yfa	509	8	counseling	counseling	NN
cord-015935-r2wd1yfa	509	9	should	should	MD
cord-015935-r2wd1yfa	509	10	be	be	VB
cord-015935-r2wd1yfa	509	11	provided	provide	VBN
cord-015935-r2wd1yfa	509	12	according	accord	VBG
cord-015935-r2wd1yfa	509	13	to	to	IN
cord-015935-r2wd1yfa	509	14	multifactorial	multifactorial	JJ
cord-015935-r2wd1yfa	509	15	inheritance	inheritance	NN
cord-015935-r2wd1yfa	509	16	.	.	.
cord-015935-r2wd1yfa	510	1	That	that	RB
cord-015935-r2wd1yfa	510	2	is	is	RB
cord-015935-r2wd1yfa	510	3	,	,	,
cord-015935-r2wd1yfa	510	4	4	4	CD
cord-015935-r2wd1yfa	510	5	%	%	NN
cord-015935-r2wd1yfa	510	6	recurrence	recurrence	NN
cord-015935-r2wd1yfa	510	7	rate	rate	NN
cord-015935-r2wd1yfa	510	8	if	if	IN
cord-015935-r2wd1yfa	510	9	the	the	DT
cord-015935-r2wd1yfa	510	10	proband	proband	NN
cord-015935-r2wd1yfa	510	11	is	be	VBZ
cord-015935-r2wd1yfa	510	12	a	a	DT
cord-015935-r2wd1yfa	510	13	girl	girl	NN
cord-015935-r2wd1yfa	510	14	and	and	CC
cord-015935-r2wd1yfa	510	15	7	7	CD
cord-015935-r2wd1yfa	510	16	%	%	NN
cord-015935-r2wd1yfa	510	17	if	if	IN
cord-015935-r2wd1yfa	510	18	the	the	DT
cord-015935-r2wd1yfa	510	19	proband	proband	NN
cord-015935-r2wd1yfa	510	20	is	be	VBZ
cord-015935-r2wd1yfa	510	21	a	a	DT
cord-015935-r2wd1yfa	510	22	boy	boy	NN
cord-015935-r2wd1yfa	510	23	.	.	.
cord-015935-r2wd1yfa	511	1	If	if	IN
cord-015935-r2wd1yfa	511	2	a	a	DT
cord-015935-r2wd1yfa	511	3	second	second	JJ
cord-015935-r2wd1yfa	511	4	child	child	NN
cord-015935-r2wd1yfa	511	5	has	have	VBZ
cord-015935-r2wd1yfa	511	6	autism	autism	NN
cord-015935-r2wd1yfa	511	7	,	,	,
cord-015935-r2wd1yfa	511	8	a	a	DT
cord-015935-r2wd1yfa	511	9	reasonable	reasonable	JJ
cord-015935-r2wd1yfa	511	10	recurrence	recurrence	NN
cord-015935-r2wd1yfa	511	11	rate	rate	NN
cord-015935-r2wd1yfa	511	12	,	,	,
cord-015935-r2wd1yfa	511	13	based	base	VBN
cord-015935-r2wd1yfa	511	14	upon	upon	IN
cord-015935-r2wd1yfa	511	15	published	publish	VBN
cord-015935-r2wd1yfa	511	16	reports	report	NNS
cord-015935-r2wd1yfa	511	17	,	,	,
cord-015935-r2wd1yfa	511	18	is	be	VBZ
cord-015935-r2wd1yfa	511	19	30	30	CD
cord-015935-r2wd1yfa	511	20	%	%	NN
cord-015935-r2wd1yfa	511	21	.	.	.
cord-015935-r2wd1yfa	512	1	Advances	advance	NNS
cord-015935-r2wd1yfa	512	2	in	in	IN
cord-015935-r2wd1yfa	512	3	autism	autism	NN
cord-015935-r2wd1yfa	512	4	genetics	genetic	NNS
cord-015935-r2wd1yfa	512	5	:	:	:
cord-015935-r2wd1yfa	513	1	On	on	IN
cord-015935-r2wd1yfa	513	2	the	the	DT
cord-015935-r2wd1yfa	513	3	threshold	threshold	NN
cord-015935-r2wd1yfa	513	4	of	of	IN
cord-015935-r2wd1yfa	513	5	a	a	DT
cord-015935-r2wd1yfa	513	6	new	new	JJ
cord-015935-r2wd1yfa	513	7	neurobiology	neurobiology	NN
cord-015935-r2wd1yfa	513	8	Linkage	Linkage	NNP
cord-015935-r2wd1yfa	513	9	,	,	,
cord-015935-r2wd1yfa	513	10	association	association	NN
cord-015935-r2wd1yfa	513	11	,	,	,
cord-015935-r2wd1yfa	513	12	and	and	CC
cord-015935-r2wd1yfa	513	13	geneexpression	geneexpression	NN
cord-015935-r2wd1yfa	513	14	analyses	analysis	NNS
cord-015935-r2wd1yfa	513	15	identify	identify	VBP
cord-015935-r2wd1yfa	513	16	CNTNAP2	CNTNAP2	NNP
cord-015935-r2wd1yfa	513	17	as	as	IN
cord-015935-r2wd1yfa	513	18	an	an	DT
cord-015935-r2wd1yfa	513	19	autism	autism	NN
cord-015935-r2wd1yfa	513	20	-	-	HYPH
cord-015935-r2wd1yfa	513	21	susceptibility	susceptibility	NN
cord-015935-r2wd1yfa	513	22	gene	gene	NN
cord-015935-r2wd1yfa	513	23	Memantine	Memantine	NNP
cord-015935-r2wd1yfa	513	24	lowers	lower	VBZ
cord-015935-r2wd1yfa	513	25	amyloid	amyloid	NN
cord-015935-r2wd1yfa	513	26	-	-	HYPH
cord-015935-r2wd1yfa	513	27	beta	beta	NN
cord-015935-r2wd1yfa	513	28	peptide	peptide	JJ
cord-015935-r2wd1yfa	513	29	levels	level	NNS
cord-015935-r2wd1yfa	513	30	in	in	IN
cord-015935-r2wd1yfa	513	31	neuronal	neuronal	JJ
cord-015935-r2wd1yfa	513	32	cultures	culture	NNS
cord-015935-r2wd1yfa	513	33	and	and	CC
cord-015935-r2wd1yfa	513	34	in	in	IN
cord-015935-r2wd1yfa	513	35	APP	app	NN
cord-015935-r2wd1yfa	513	36	/	/	SYM
cord-015935-r2wd1yfa	513	37	PS1	PS1	NNP
cord-015935-r2wd1yfa	513	38	transgenic	transgenic	JJ
cord-015935-r2wd1yfa	513	39	mice	mouse	NNS
cord-015935-r2wd1yfa	513	40	Investigation	Investigation	NNP
cord-015935-r2wd1yfa	513	41	of	of	IN
cord-015935-r2wd1yfa	513	42	potential	potential	JJ
cord-015935-r2wd1yfa	513	43	gene	gene	NN
cord-015935-r2wd1yfa	513	44	-	-	HYPH
cord-015935-r2wd1yfa	513	45	gene	gene	NN
cord-015935-r2wd1yfa	513	46	interactions	interaction	NNS
cord-015935-r2wd1yfa	513	47	between	between	IN
cord-015935-r2wd1yfa	513	48	APOE	APOE	NNP
cord-015935-r2wd1yfa	513	49	and	and	CC
cord-015935-r2wd1yfa	513	50	RELN	RELN	NNP
cord-015935-r2wd1yfa	513	51	contributing	contribute	VBG
cord-015935-r2wd1yfa	513	52	to	to	IN
cord-015935-r2wd1yfa	513	53	autism	autism	NN
cord-015935-r2wd1yfa	513	54	risk	risk	NN
cord-015935-r2wd1yfa	513	55	Molecular	molecular	JJ
cord-015935-r2wd1yfa	513	56	genetic	genetic	JJ
cord-015935-r2wd1yfa	513	57	basis	basis	NN
cord-015935-r2wd1yfa	513	58	of	of	IN
cord-015935-r2wd1yfa	513	59	tuberous	tuberous	JJ
cord-015935-r2wd1yfa	513	60	sclerosis	sclerosis	NN
cord-015935-r2wd1yfa	513	61	complex	complex	NN
cord-015935-r2wd1yfa	513	62	:	:	:
cord-015935-r2wd1yfa	514	1	From	from	IN
cord-015935-r2wd1yfa	514	2	bench	bench	NN
cord-015935-r2wd1yfa	514	3	to	to	IN
cord-015935-r2wd1yfa	514	4	bedside	bedside	NN
cord-015935-r2wd1yfa	514	5	Peripheral	peripheral	JJ
cord-015935-r2wd1yfa	514	6	biomarkers	biomarker	NNS
cord-015935-r2wd1yfa	514	7	in	in	IN
cord-015935-r2wd1yfa	514	8	autism	autism	NN
cord-015935-r2wd1yfa	514	9	:	:	:
cord-015935-r2wd1yfa	514	10	Secreted	secrete	VBN
cord-015935-r2wd1yfa	514	11	amyloid	amyloid	NN
cord-015935-r2wd1yfa	514	12	precursor	precursor	NN
cord-015935-r2wd1yfa	514	13	protein	protein	NN
cord-015935-r2wd1yfa	514	14	-	-	HYPH
cord-015935-r2wd1yfa	514	15	alpha	alpha	NN
cord-015935-r2wd1yfa	514	16	as	as	IN
cord-015935-r2wd1yfa	514	17	a	a	DT
cord-015935-r2wd1yfa	514	18	probable	probable	JJ
cord-015935-r2wd1yfa	514	19	key	key	JJ
cord-015935-r2wd1yfa	514	20	player	player	NN
cord-015935-r2wd1yfa	514	21	in	in	IN
cord-015935-r2wd1yfa	514	22	early	early	JJ
cord-015935-r2wd1yfa	514	23	diagnosis	diagnosis	NN
cord-015935-r2wd1yfa	514	24	Autism	Autism	NNP
cord-015935-r2wd1yfa	514	25	as	as	IN
cord-015935-r2wd1yfa	514	26	a	a	DT
cord-015935-r2wd1yfa	514	27	strongly	strongly	RB
cord-015935-r2wd1yfa	514	28	genetic	genetic	JJ
cord-015935-r2wd1yfa	514	29	disorder	disorder	NN
cord-015935-r2wd1yfa	514	30	:	:	:
cord-015935-r2wd1yfa	515	1	Evidence	evidence	NN
cord-015935-r2wd1yfa	515	2	from	from	IN
cord-015935-r2wd1yfa	515	3	a	a	DT
cord-015935-r2wd1yfa	515	4	British	british	JJ
cord-015935-r2wd1yfa	515	5	twin	twin	JJ
cord-015935-r2wd1yfa	515	6	study	study	NN
cord-015935-r2wd1yfa	516	1	Molecular	molecular	JJ
cord-015935-r2wd1yfa	516	2	cytogenetic	cytogenetic	JJ
cord-015935-r2wd1yfa	516	3	analysis	analysis	NN
cord-015935-r2wd1yfa	516	4	and	and	CC
cord-015935-r2wd1yfa	516	5	resequencing	resequencing	NN
cord-015935-r2wd1yfa	516	6	of	of	IN
cord-015935-r2wd1yfa	516	7	contactin	contactin	NNP
cord-015935-r2wd1yfa	516	8	associated	associated	JJ
cord-015935-r2wd1yfa	516	9	protein	protein	NN
cord-015935-r2wd1yfa	516	10	-	-	HYPH
cord-015935-r2wd1yfa	516	11	like	like	JJ
cord-015935-r2wd1yfa	516	12	2	2	CD
cord-015935-r2wd1yfa	516	13	in	in	IN
cord-015935-r2wd1yfa	517	1	autism	autism	NNP
cord-015935-r2wd1yfa	517	2	spectrum	spectrum	NNP
cord-015935-r2wd1yfa	517	3	disorders	disorder	NNS
cord-015935-r2wd1yfa	517	4	Examination	Examination	NNP
cord-015935-r2wd1yfa	517	5	of	of	IN
cord-015935-r2wd1yfa	517	6	potential	potential	JJ
cord-015935-r2wd1yfa	517	7	overlap	overlap	NN
cord-015935-r2wd1yfa	517	8	in	in	IN
cord-015935-r2wd1yfa	517	9	autism	autism	NN
cord-015935-r2wd1yfa	517	10	and	and	CC
cord-015935-r2wd1yfa	517	11	language	language	NN
cord-015935-r2wd1yfa	517	12	loci	locus	NNS
cord-015935-r2wd1yfa	517	13	on	on	IN
cord-015935-r2wd1yfa	517	14	chromosomes	chromosome	NNS
cord-015935-r2wd1yfa	517	15	2	2	CD
cord-015935-r2wd1yfa	517	16	,	,	,
cord-015935-r2wd1yfa	517	17	7	7	CD
cord-015935-r2wd1yfa	517	18	,	,	,
cord-015935-r2wd1yfa	517	19	and	and	CC
cord-015935-r2wd1yfa	517	20	13	13	CD
cord-015935-r2wd1yfa	517	21	in	in	IN
cord-015935-r2wd1yfa	517	22	two	two	CD
cord-015935-r2wd1yfa	517	23	independent	independent	JJ
cord-015935-r2wd1yfa	517	24	samples	sample	NNS
cord-015935-r2wd1yfa	517	25	ascertained	ascertain	VBN
cord-015935-r2wd1yfa	517	26	for	for	IN
cord-015935-r2wd1yfa	517	27	specific	specific	JJ
cord-015935-r2wd1yfa	517	28	language	language	NN
cord-015935-r2wd1yfa	517	29	impairment	impairment	NN
cord-015935-r2wd1yfa	518	1	A	a	DT
cord-015935-r2wd1yfa	518	2	major	major	JJ
cord-015935-r2wd1yfa	518	3	susceptibility	susceptibility	NN
cord-015935-r2wd1yfa	518	4	locus	locus	NN
cord-015935-r2wd1yfa	518	5	for	for	IN
cord-015935-r2wd1yfa	518	6	specific	specific	JJ
cord-015935-r2wd1yfa	518	7	language	language	NN
cord-015935-r2wd1yfa	518	8	impairment	impairment	NN
cord-015935-r2wd1yfa	518	9	is	be	VBZ
cord-015935-r2wd1yfa	518	10	located	locate	VBN
cord-015935-r2wd1yfa	518	11	on	on	IN
cord-015935-r2wd1yfa	518	12	13q21	13q21	CD
cord-015935-r2wd1yfa	518	13	Molecular	Molecular	NNP
cord-015935-r2wd1yfa	518	14	Analysis	Analysis	NNP
cord-015935-r2wd1yfa	518	15	of	of	IN
cord-015935-r2wd1yfa	518	16	Fragile	Fragile	NNP
cord-015935-r2wd1yfa	518	17	X	X	NNP
cord-015935-r2wd1yfa	518	18	Syndrome	syndrome	NN
cord-015935-r2wd1yfa	518	19	Therapeutic	therapeutic	JJ
cord-015935-r2wd1yfa	518	20	implications	implication	NNS
cord-015935-r2wd1yfa	518	21	of	of	IN
cord-015935-r2wd1yfa	518	22	the	the	DT
cord-015935-r2wd1yfa	518	23	mGluR	mglur	JJ
cord-015935-r2wd1yfa	518	24	theory	theory	NN
cord-015935-r2wd1yfa	518	25	of	of	IN
cord-015935-r2wd1yfa	518	26	fragile	fragile	JJ
cord-015935-r2wd1yfa	518	27	X	x	NN
cord-015935-r2wd1yfa	518	28	mental	mental	JJ
cord-015935-r2wd1yfa	518	29	retardation	retardation	NN
cord-015935-r2wd1yfa	519	1	The	the	DT
cord-015935-r2wd1yfa	519	2	mGluR	mglur	JJ
cord-015935-r2wd1yfa	519	3	theory	theory	NN
cord-015935-r2wd1yfa	519	4	of	of	IN
cord-015935-r2wd1yfa	519	5	fragile	fragile	JJ
cord-015935-r2wd1yfa	519	6	X	x	NN
cord-015935-r2wd1yfa	519	7	mental	mental	JJ
cord-015935-r2wd1yfa	519	8	retardation	retardation	NN
cord-015935-r2wd1yfa	519	9	Fragile	Fragile	NNP
cord-015935-r2wd1yfa	519	10	X	x	NN
cord-015935-r2wd1yfa	519	11	-	-	JJ
cord-015935-r2wd1yfa	519	12	associated	associate	VBN
cord-015935-r2wd1yfa	519	13	tremor	tremor	NN
cord-015935-r2wd1yfa	519	14	/	/	SYM
cord-015935-r2wd1yfa	519	15	ataxia	ataxia	NN
cord-015935-r2wd1yfa	519	16	syndrome	syndrome	NN
cord-015935-r2wd1yfa	519	17	in	in	IN
cord-015935-r2wd1yfa	519	18	sisters	sister	NNS
cord-015935-r2wd1yfa	519	19	related	relate	VBN
cord-015935-r2wd1yfa	519	20	to	to	IN
cord-015935-r2wd1yfa	519	21	X	x	NN
cord-015935-r2wd1yfa	519	22	-	-	NN
cord-015935-r2wd1yfa	519	23	inactivation	inactivation	JJ
cord-015935-r2wd1yfa	519	24	Subset	subset	NN
cord-015935-r2wd1yfa	519	25	of	of	IN
cord-015935-r2wd1yfa	519	26	individuals	individual	NNS
cord-015935-r2wd1yfa	519	27	with	with	IN
cord-015935-r2wd1yfa	519	28	autism	autism	NN
cord-015935-r2wd1yfa	519	29	spectrum	spectrum	NN
cord-015935-r2wd1yfa	519	30	disorders	disorder	NNS
cord-015935-r2wd1yfa	519	31	and	and	CC
cord-015935-r2wd1yfa	519	32	extreme	extreme	JJ
cord-015935-r2wd1yfa	519	33	macrocephaly	macrocephaly	NN
cord-015935-r2wd1yfa	519	34	associated	associate	VBN
cord-015935-r2wd1yfa	519	35	with	with	IN
cord-015935-r2wd1yfa	519	36	germline	germline	JJ
cord-015935-r2wd1yfa	519	37	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	519	38	tumour	tumour	NN
cord-015935-r2wd1yfa	519	39	suppressor	suppressor	NN
cord-015935-r2wd1yfa	519	40	gene	gene	NN
cord-015935-r2wd1yfa	519	41	mutations	mutation	NNS
cord-015935-r2wd1yfa	519	42	Mutation	Mutation	NNP
cord-015935-r2wd1yfa	519	43	screening	screening	NN
cord-015935-r2wd1yfa	519	44	of	of	IN
cord-015935-r2wd1yfa	519	45	the	the	DT
cord-015935-r2wd1yfa	519	46	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	519	47	gene	gene	NN
cord-015935-r2wd1yfa	519	48	in	in	IN
cord-015935-r2wd1yfa	519	49	patients	patient	NNS
cord-015935-r2wd1yfa	519	50	with	with	IN
cord-015935-r2wd1yfa	519	51	autism	autism	NN
cord-015935-r2wd1yfa	519	52	spectrum	spectrum	NN
cord-015935-r2wd1yfa	519	53	disorders	disorder	NNS
cord-015935-r2wd1yfa	519	54	and	and	CC
cord-015935-r2wd1yfa	519	55	macrocephaly	macrocephaly	NNP
cord-015935-r2wd1yfa	519	56	Replication	Replication	NNP
cord-015935-r2wd1yfa	519	57	of	of	IN
cord-015935-r2wd1yfa	519	58	autism	autism	NN
cord-015935-r2wd1yfa	519	59	linkage	linkage	NN
cord-015935-r2wd1yfa	519	60	:	:	:
cord-015935-r2wd1yfa	520	1	Finemapping	finemappe	VBG
cord-015935-r2wd1yfa	520	2	peak	peak	NN
cord-015935-r2wd1yfa	520	3	at	at	IN
cord-015935-r2wd1yfa	520	4	17q21	17q21	CD
cord-015935-r2wd1yfa	520	5	An	an	DT
cord-015935-r2wd1yfa	520	6	autosomal	autosomal	JJ
cord-015935-r2wd1yfa	520	7	genomic	genomic	JJ
cord-015935-r2wd1yfa	520	8	screen	screen	NN
cord-015935-r2wd1yfa	520	9	for	for	IN
cord-015935-r2wd1yfa	520	10	autism	autism	NN
cord-015935-r2wd1yfa	521	1	An	an	DT
cord-015935-r2wd1yfa	521	2	autosomal	autosomal	JJ
cord-015935-r2wd1yfa	521	3	genomic	genomic	JJ
cord-015935-r2wd1yfa	521	4	screen	screen	NN
cord-015935-r2wd1yfa	521	5	for	for	IN
cord-015935-r2wd1yfa	521	6	autism	autism	NN
cord-015935-r2wd1yfa	522	1	Autistic	autistic	JJ
cord-015935-r2wd1yfa	522	2	children	child	NNS
cord-015935-r2wd1yfa	522	3	and	and	CC
cord-015935-r2wd1yfa	522	4	their	-PRON-	PRP$
cord-015935-r2wd1yfa	522	5	first	first	JJ
cord-015935-r2wd1yfa	522	6	degree	degree	NN
cord-015935-r2wd1yfa	522	7	relatives	relative	NNS
cord-015935-r2wd1yfa	522	8	:	:	:
cord-015935-r2wd1yfa	523	1	Relationships	relationship	NNS
cord-015935-r2wd1yfa	523	2	between	between	IN
cord-015935-r2wd1yfa	523	3	serotonin	serotonin	NN
cord-015935-r2wd1yfa	523	4	and	and	CC
cord-015935-r2wd1yfa	523	5	norepinephrine	norepinephrine	NN
cord-015935-r2wd1yfa	523	6	levels	level	NNS
cord-015935-r2wd1yfa	523	7	and	and	CC
cord-015935-r2wd1yfa	523	8	intelligence	intelligence	NN
cord-015935-r2wd1yfa	523	9	Autism	autism	NN
cord-015935-r2wd1yfa	523	10	or	or	CC
cord-015935-r2wd1yfa	523	11	atypical	atypical	JJ
cord-015935-r2wd1yfa	523	12	autism	autism	NN
cord-015935-r2wd1yfa	523	13	in	in	IN
cord-015935-r2wd1yfa	523	14	maternally	maternally	RB
cord-015935-r2wd1yfa	523	15	but	but	CC
cord-015935-r2wd1yfa	523	16	not	not	RB
cord-015935-r2wd1yfa	523	17	paternally	paternally	RB
cord-015935-r2wd1yfa	523	18	derived	derive	VBN
cord-015935-r2wd1yfa	523	19	proximal	proximal	JJ
cord-015935-r2wd1yfa	523	20	15q	15q	CD
cord-015935-r2wd1yfa	523	21	duplication	duplication	NN
cord-015935-r2wd1yfa	523	22	Autism	Autism	NNP
cord-015935-r2wd1yfa	523	23	,	,	,
cord-015935-r2wd1yfa	523	24	a	a	DT
cord-015935-r2wd1yfa	523	25	brain	brain	NN
cord-015935-r2wd1yfa	523	26	developmental	developmental	JJ
cord-015935-r2wd1yfa	523	27	disorder	disorder	NN
cord-015935-r2wd1yfa	523	28	:	:	:
cord-015935-r2wd1yfa	523	29	Some	some	DT
cord-015935-r2wd1yfa	523	30	new	new	JJ
cord-015935-r2wd1yfa	523	31	pathophysiologic	pathophysiologic	NN
cord-015935-r2wd1yfa	523	32	and	and	CC
cord-015935-r2wd1yfa	523	33	genetics	genetics	NN
cord-015935-r2wd1yfa	523	34	findings	finding	NNS
cord-015935-r2wd1yfa	523	35	Evidence	evidence	NN
cord-015935-r2wd1yfa	523	36	of	of	IN
cord-015935-r2wd1yfa	523	37	brain	brain	NN
cord-015935-r2wd1yfa	523	38	overgrowth	overgrowth	NN
cord-015935-r2wd1yfa	523	39	in	in	IN
cord-015935-r2wd1yfa	523	40	the	the	DT
cord-015935-r2wd1yfa	523	41	first	first	JJ
cord-015935-r2wd1yfa	523	42	year	year	NN
cord-015935-r2wd1yfa	523	43	of	of	IN
cord-015935-r2wd1yfa	523	44	life	life	NN
cord-015935-r2wd1yfa	523	45	in	in	IN
cord-015935-r2wd1yfa	523	46	autism	autism	NN
cord-015935-r2wd1yfa	523	47	Unusual	unusual	JJ
cord-015935-r2wd1yfa	523	48	brain	brain	NN
cord-015935-r2wd1yfa	523	49	growth	growth	NN
cord-015935-r2wd1yfa	523	50	patterns	pattern	NNS
cord-015935-r2wd1yfa	523	51	in	in	IN
cord-015935-r2wd1yfa	523	52	early	early	JJ
cord-015935-r2wd1yfa	523	53	life	life	NN
cord-015935-r2wd1yfa	523	54	in	in	IN
cord-015935-r2wd1yfa	523	55	patients	patient	NNS
cord-015935-r2wd1yfa	523	56	with	with	IN
cord-015935-r2wd1yfa	523	57	autistic	autistic	JJ
cord-015935-r2wd1yfa	523	58	disorder	disorder	NN
cord-015935-r2wd1yfa	523	59	:	:	:
cord-015935-r2wd1yfa	524	1	An	an	DT
cord-015935-r2wd1yfa	524	2	MRI	MRI	NNP
cord-015935-r2wd1yfa	524	3	study	study	NN
cord-015935-r2wd1yfa	524	4	Factor	factor	NN
cord-015935-r2wd1yfa	524	5	analysis	analysis	NN
cord-015935-r2wd1yfa	524	6	of	of	IN
cord-015935-r2wd1yfa	524	7	restricted	restricted	JJ
cord-015935-r2wd1yfa	524	8	and	and	CC
cord-015935-r2wd1yfa	524	9	repetitive	repetitive	JJ
cord-015935-r2wd1yfa	524	10	behaviors	behavior	NNS
cord-015935-r2wd1yfa	524	11	in	in	IN
cord-015935-r2wd1yfa	524	12	autism	autism	NN
cord-015935-r2wd1yfa	524	13	using	use	VBG
cord-015935-r2wd1yfa	524	14	the	the	DT
cord-015935-r2wd1yfa	524	15	autism	autism	NN
cord-015935-r2wd1yfa	524	16	diagnostic	diagnostic	JJ
cord-015935-r2wd1yfa	524	17	interview	interview	NN
cord-015935-r2wd1yfa	524	18	-	-	HYPH
cord-015935-r2wd1yfa	524	19	R	R	NNP
cord-015935-r2wd1yfa	524	20	Neuron	Neuron	NNP
cord-015935-r2wd1yfa	524	21	,	,	,
cord-015935-r2wd1yfa	524	22	know	know	VB
cord-015935-r2wd1yfa	524	23	thy	thy	PRP$
cord-015935-r2wd1yfa	524	24	neighbor	neighbor	NN
cord-015935-r2wd1yfa	524	25	Correction	correction	NN
cord-015935-r2wd1yfa	524	26	of	of	IN
cord-015935-r2wd1yfa	524	27	fragile	fragile	JJ
cord-015935-r2wd1yfa	524	28	X	x	NN
cord-015935-r2wd1yfa	524	29	syndrome	syndrome	NN
cord-015935-r2wd1yfa	524	30	in	in	IN
cord-015935-r2wd1yfa	524	31	mice	mouse	NNS
cord-015935-r2wd1yfa	524	32	Mutations	Mutations	NNPS
cord-015935-r2wd1yfa	524	33	in	in	IN
cord-015935-r2wd1yfa	524	34	the	the	DT
cord-015935-r2wd1yfa	524	35	gene	gene	NN
cord-015935-r2wd1yfa	524	36	encoding	encode	VBG
cord-015935-r2wd1yfa	524	37	the	the	DT
cord-015935-r2wd1yfa	524	38	synaptic	synaptic	JJ
cord-015935-r2wd1yfa	524	39	scaffolding	scaffolding	NN
cord-015935-r2wd1yfa	524	40	protein	protein	NN
cord-015935-r2wd1yfa	525	1	SHANK3	SHANK3	NNP
cord-015935-r2wd1yfa	525	2	are	be	VBP
cord-015935-r2wd1yfa	525	3	associated	associate	VBN
cord-015935-r2wd1yfa	525	4	with	with	IN
cord-015935-r2wd1yfa	525	5	autism	autism	NN
cord-015935-r2wd1yfa	525	6	spectrum	spectrum	NN
cord-015935-r2wd1yfa	525	7	disorders	disorder	NNS
cord-015935-r2wd1yfa	525	8	Gene	Gene	NNP
cord-015935-r2wd1yfa	525	9	expression	expression	NN
cord-015935-r2wd1yfa	525	10	profiles	profile	NNS
cord-015935-r2wd1yfa	525	11	in	in	IN
cord-015935-r2wd1yfa	525	12	a	a	DT
cord-015935-r2wd1yfa	525	13	transgenic	transgenic	JJ
cord-015935-r2wd1yfa	525	14	animal	animal	NN
cord-015935-r2wd1yfa	525	15	model	model	NN
cord-015935-r2wd1yfa	525	16	of	of	IN
cord-015935-r2wd1yfa	525	17	fragile	fragile	JJ
cord-015935-r2wd1yfa	525	18	X	X	NNP
cord-015935-r2wd1yfa	525	19	syndrome	syndrome	NN
cord-015935-r2wd1yfa	525	20	Autism	autism	NN
cord-015935-r2wd1yfa	525	21	is	be	VBZ
cord-015935-r2wd1yfa	525	22	not	not	RB
cord-015935-r2wd1yfa	525	23	associated	associate	VBN
cord-015935-r2wd1yfa	525	24	with	with	IN
cord-015935-r2wd1yfa	525	25	the	the	DT
cord-015935-r2wd1yfa	525	26	fragile	fragile	JJ
cord-015935-r2wd1yfa	525	27	X	x	NN
cord-015935-r2wd1yfa	525	28	syndrome	syndrome	NN
cord-015935-r2wd1yfa	525	29	Mouse	mouse	NN
cord-015935-r2wd1yfa	525	30	neurexin-1alpha	neurexin-1alpha	NNS
cord-015935-r2wd1yfa	525	31	deletion	deletion	NN
cord-015935-r2wd1yfa	525	32	causes	cause	NNS
cord-015935-r2wd1yfa	525	33	correlated	correlate	VBD
cord-015935-r2wd1yfa	525	34	electrophysiological	electrophysiological	JJ
cord-015935-r2wd1yfa	525	35	and	and	CC
cord-015935-r2wd1yfa	525	36	behavioral	behavioral	JJ
cord-015935-r2wd1yfa	525	37	changes	change	NNS
cord-015935-r2wd1yfa	525	38	consistent	consistent	JJ
cord-015935-r2wd1yfa	525	39	with	with	IN
cord-015935-r2wd1yfa	525	40	cognitive	cognitive	JJ
cord-015935-r2wd1yfa	525	41	impairments	impairment	NNS
cord-015935-r2wd1yfa	526	1	High	high	JJ
cord-015935-r2wd1yfa	526	2	frequency	frequency	NN
cord-015935-r2wd1yfa	526	3	of	of	IN
cord-015935-r2wd1yfa	526	4	neurexin	neurexin	NNP
cord-015935-r2wd1yfa	526	5	1beta	1beta	CD
cord-015935-r2wd1yfa	526	6	signal	signal	NNP
cord-015935-r2wd1yfa	526	7	peptide	peptide	JJ
cord-015935-r2wd1yfa	526	8	structural	structural	JJ
cord-015935-r2wd1yfa	526	9	variants	variant	NNS
cord-015935-r2wd1yfa	526	10	in	in	IN
cord-015935-r2wd1yfa	526	11	patients	patient	NNS
cord-015935-r2wd1yfa	526	12	with	with	IN
cord-015935-r2wd1yfa	526	13	autism	autism	NN
cord-015935-r2wd1yfa	526	14	Infantile	infantile	JJ
cord-015935-r2wd1yfa	526	15	autism	autism	NN
cord-015935-r2wd1yfa	526	16	:	:	:
cord-015935-r2wd1yfa	527	1	A	a	DT
cord-015935-r2wd1yfa	527	2	genetic	genetic	JJ
cord-015935-r2wd1yfa	527	3	study	study	NN
cord-015935-r2wd1yfa	527	4	of	of	IN
cord-015935-r2wd1yfa	527	5	21	21	CD
cord-015935-r2wd1yfa	527	6	twin	twin	JJ
cord-015935-r2wd1yfa	527	7	pairs	pair	NNS
cord-015935-r2wd1yfa	527	8	The	the	DT
cord-015935-r2wd1yfa	527	9	genetics	genetic	NNS
cord-015935-r2wd1yfa	527	10	of	of	IN
cord-015935-r2wd1yfa	527	11	autistic	autistic	JJ
cord-015935-r2wd1yfa	527	12	disorders	disorder	NNS
cord-015935-r2wd1yfa	527	13	and	and	CC
cord-015935-r2wd1yfa	527	14	its	-PRON-	PRP$
cord-015935-r2wd1yfa	527	15	clinical	clinical	JJ
cord-015935-r2wd1yfa	527	16	relevance	relevance	NN
cord-015935-r2wd1yfa	527	17	:	:	:
cord-015935-r2wd1yfa	527	18	A	a	DT
cord-015935-r2wd1yfa	527	19	review	review	NN
cord-015935-r2wd1yfa	527	20	of	of	IN
cord-015935-r2wd1yfa	527	21	the	the	DT
cord-015935-r2wd1yfa	527	22	literature	literature	NN
cord-015935-r2wd1yfa	527	23	Evidence	evidence	NN
cord-015935-r2wd1yfa	527	24	that	that	IN
cord-015935-r2wd1yfa	527	25	the	the	DT
cord-015935-r2wd1yfa	527	26	gene	gene	NN
cord-015935-r2wd1yfa	527	27	for	for	IN
cord-015935-r2wd1yfa	527	28	tuberous	tuberous	JJ
cord-015935-r2wd1yfa	527	29	sclerosis	sclerosis	NN
cord-015935-r2wd1yfa	527	30	is	be	VBZ
cord-015935-r2wd1yfa	527	31	on	on	IN
cord-015935-r2wd1yfa	527	32	chromosome	chromosome	NN
cord-015935-r2wd1yfa	527	33	9	9	CD
cord-015935-r2wd1yfa	527	34	Advances	advance	NNS
cord-015935-r2wd1yfa	527	35	in	in	IN
cord-015935-r2wd1yfa	527	36	autism	autism	NN
cord-015935-r2wd1yfa	527	37	Neuroscience	Neuroscience	NNP
cord-015935-r2wd1yfa	527	38	in	in	IN
cord-015935-r2wd1yfa	527	39	the	the	DT
cord-015935-r2wd1yfa	527	40	era	era	NN
cord-015935-r2wd1yfa	527	41	of	of	IN
cord-015935-r2wd1yfa	527	42	functional	functional	JJ
cord-015935-r2wd1yfa	527	43	genomics	genomic	NNS
cord-015935-r2wd1yfa	527	44	and	and	CC
cord-015935-r2wd1yfa	527	45	systems	system	NNS
cord-015935-r2wd1yfa	527	46	biology	biology	NNP
cord-015935-r2wd1yfa	527	47	Autism	Autism	NNP
cord-015935-r2wd1yfa	527	48	genome	genome	NN
cord-015935-r2wd1yfa	527	49	-	-	HYPH
cord-015935-r2wd1yfa	527	50	wide	wide	JJ
cord-015935-r2wd1yfa	527	51	copy	copy	NN
cord-015935-r2wd1yfa	527	52	number	number	NN
cord-015935-r2wd1yfa	527	53	variation	variation	NN
cord-015935-r2wd1yfa	527	54	reveals	reveal	VBZ
cord-015935-r2wd1yfa	527	55	ubiquitin	ubiquitin	JJ
cord-015935-r2wd1yfa	527	56	and	and	CC
cord-015935-r2wd1yfa	527	57	neuronal	neuronal	JJ
cord-015935-r2wd1yfa	527	58	genes	gene	NNS
cord-015935-r2wd1yfa	528	1	Recent	recent	JJ
cord-015935-r2wd1yfa	528	2	advances	advance	NNS
cord-015935-r2wd1yfa	528	3	in	in	IN
cord-015935-r2wd1yfa	528	4	the	the	DT
cord-015935-r2wd1yfa	528	5	genetics	genetic	NNS
cord-015935-r2wd1yfa	528	6	of	of	IN
cord-015935-r2wd1yfa	528	7	autism	autism	NN
cord-015935-r2wd1yfa	529	1	The	the	DT
cord-015935-r2wd1yfa	529	2	physical	physical	JJ
cord-015935-r2wd1yfa	529	3	and	and	CC
cord-015935-r2wd1yfa	529	4	behavioral	behavioral	JJ
cord-015935-r2wd1yfa	529	5	phenotype	phenotype	NN
cord-015935-r2wd1yfa	529	6	Lessons	lesson	NNS
cord-015935-r2wd1yfa	529	7	from	from	IN
cord-015935-r2wd1yfa	529	8	fragile	fragile	JJ
cord-015935-r2wd1yfa	529	9	X	x	NN
cord-015935-r2wd1yfa	529	10	regarding	regard	VBG
cord-015935-r2wd1yfa	529	11	neurobiology	neurobiology	NN
cord-015935-r2wd1yfa	529	12	,	,	,
cord-015935-r2wd1yfa	529	13	autism	autism	NN
cord-015935-r2wd1yfa	529	14	,	,	,
cord-015935-r2wd1yfa	529	15	and	and	CC
cord-015935-r2wd1yfa	529	16	neurodegeneration	neurodegeneration	NN
cord-015935-r2wd1yfa	529	17	Intention	intention	NN
cord-015935-r2wd1yfa	529	18	tremor	tremor	NN
cord-015935-r2wd1yfa	529	19	,	,	,
cord-015935-r2wd1yfa	529	20	parkinsonism	parkinsonism	NN
cord-015935-r2wd1yfa	529	21	,	,	,
cord-015935-r2wd1yfa	529	22	and	and	CC
cord-015935-r2wd1yfa	529	23	generalized	generalized	JJ
cord-015935-r2wd1yfa	529	24	brain	brain	NN
cord-015935-r2wd1yfa	529	25	atrophy	atrophy	NN
cord-015935-r2wd1yfa	529	26	in	in	IN
cord-015935-r2wd1yfa	529	27	male	male	JJ
cord-015935-r2wd1yfa	529	28	carriers	carrier	NNS
cord-015935-r2wd1yfa	529	29	of	of	IN
cord-015935-r2wd1yfa	529	30	fragile	fragile	JJ
cord-015935-r2wd1yfa	529	31	X	x	NN
cord-015935-r2wd1yfa	529	32	Abnormal	abnormal	JJ
cord-015935-r2wd1yfa	529	33	asymmetry	asymmetry	NN
cord-015935-r2wd1yfa	529	34	in	in	IN
cord-015935-r2wd1yfa	529	35	language	language	NN
cord-015935-r2wd1yfa	529	36	association	association	NNP
cord-015935-r2wd1yfa	529	37	cortex	cortex	NNP
cord-015935-r2wd1yfa	529	38	in	in	IN
cord-015935-r2wd1yfa	529	39	autism	autism	NN
cord-015935-r2wd1yfa	529	40	Localization	Localization	NNP
cord-015935-r2wd1yfa	529	41	of	of	IN
cord-015935-r2wd1yfa	529	42	white	white	JJ
cord-015935-r2wd1yfa	529	43	matter	matter	NN
cord-015935-r2wd1yfa	529	44	volume	volume	NN
cord-015935-r2wd1yfa	529	45	increase	increase	NN
cord-015935-r2wd1yfa	529	46	in	in	IN
cord-015935-r2wd1yfa	529	47	autism	autism	NN
cord-015935-r2wd1yfa	529	48	and	and	CC
cord-015935-r2wd1yfa	529	49	developmental	developmental	JJ
cord-015935-r2wd1yfa	529	50	language	language	NN
cord-015935-r2wd1yfa	529	51	disorder	disorder	NN
cord-015935-r2wd1yfa	530	1	Increasing	increase	VBG
cord-015935-r2wd1yfa	530	2	knowledge	knowledge	NN
cord-015935-r2wd1yfa	530	3	of	of	IN
cord-015935-r2wd1yfa	530	4	PTEN	PTEN	NNP
cord-015935-r2wd1yfa	530	5	germline	germline	NN
cord-015935-r2wd1yfa	530	6	mutations	mutation	NNS
cord-015935-r2wd1yfa	530	7	:	:	:
cord-015935-r2wd1yfa	531	1	Two	two	CD
cord-015935-r2wd1yfa	531	2	additional	additional	JJ
cord-015935-r2wd1yfa	531	3	patients	patient	NNS
cord-015935-r2wd1yfa	531	4	with	with	IN
cord-015935-r2wd1yfa	531	5	autism	autism	NN
cord-015935-r2wd1yfa	531	6	and	and	CC
cord-015935-r2wd1yfa	531	7	macrocephaly	macrocephaly	NNP
cord-015935-r2wd1yfa	531	8	A	A	NNP
cord-015935-r2wd1yfa	531	9	full	full	JJ
cord-015935-r2wd1yfa	531	10	genome	genome	NN
cord-015935-r2wd1yfa	531	11	screen	screen	NN
cord-015935-r2wd1yfa	531	12	for	for	IN
cord-015935-r2wd1yfa	531	13	autism	autism	NN
cord-015935-r2wd1yfa	531	14	with	with	IN
cord-015935-r2wd1yfa	531	15	evidence	evidence	NN
cord-015935-r2wd1yfa	531	16	for	for	IN
cord-015935-r2wd1yfa	531	17	linkage	linkage	NN
cord-015935-r2wd1yfa	531	18	to	to	IN
cord-015935-r2wd1yfa	531	19	a	a	DT
cord-015935-r2wd1yfa	531	20	region	region	NN
cord-015935-r2wd1yfa	531	21	on	on	IN
cord-015935-r2wd1yfa	531	22	chromosome	chromosome	NN
cord-015935-r2wd1yfa	531	23	7q	7q	CD
cord-015935-r2wd1yfa	531	24	.	.	.
cord-015935-r2wd1yfa	532	1	International	international	JJ
cord-015935-r2wd1yfa	532	2	molecular	molecular	JJ
cord-015935-r2wd1yfa	532	3	genetic	genetic	JJ
cord-015935-r2wd1yfa	532	4	study	study	NN
cord-015935-r2wd1yfa	532	5	of	of	IN
cord-015935-r2wd1yfa	532	6	autism	autism	NNP
cord-015935-r2wd1yfa	532	7	consortium	consortium	NNP
cord-015935-r2wd1yfa	532	8	Gene	Gene	NNP
cord-015935-r2wd1yfa	532	9	associated	associate	VBN
cord-015935-r2wd1yfa	532	10	with	with	IN
cord-015935-r2wd1yfa	532	11	seizures	seizure	NNS
cord-015935-r2wd1yfa	532	12	,	,	,
cord-015935-r2wd1yfa	532	13	autism	autism	NN
cord-015935-r2wd1yfa	532	14	,	,	,
cord-015935-r2wd1yfa	532	15	and	and	CC
cord-015935-r2wd1yfa	532	16	hepatomegaly	hepatomegaly	NNP
cord-015935-r2wd1yfa	532	17	in	in	IN
cord-015935-r2wd1yfa	532	18	an	an	DT
cord-015935-r2wd1yfa	532	19	Amish	amish	JJ
cord-015935-r2wd1yfa	532	20	girl	girl	NN
cord-015935-r2wd1yfa	532	21	Array	array	NN
cord-015935-r2wd1yfa	532	22	-	-	HYPH
cord-015935-r2wd1yfa	532	23	based	base	VBN
cord-015935-r2wd1yfa	532	24	comparative	comparative	JJ
cord-015935-r2wd1yfa	532	25	genomic	genomic	NN
cord-015935-r2wd1yfa	532	26	hybridisation	hybridisation	NN
cord-015935-r2wd1yfa	532	27	identifies	identify	VBZ
cord-015935-r2wd1yfa	532	28	high	high	JJ
cord-015935-r2wd1yfa	532	29	frequency	frequency	NN
cord-015935-r2wd1yfa	532	30	of	of	IN
cord-015935-r2wd1yfa	532	31	cryptic	cryptic	JJ
cord-015935-r2wd1yfa	532	32	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	532	33	rearrangements	rearrangement	NNS
cord-015935-r2wd1yfa	532	34	in	in	IN
cord-015935-r2wd1yfa	532	35	patients	patient	NNS
cord-015935-r2wd1yfa	532	36	with	with	IN
cord-015935-r2wd1yfa	532	37	syndromic	syndromic	NNP
cord-015935-r2wd1yfa	532	38	autism	autism	NN
cord-015935-r2wd1yfa	532	39	spectrum	spectrum	NN
cord-015935-r2wd1yfa	532	40	disorders	disorder	NNS
cord-015935-r2wd1yfa	532	41	Mutations	Mutations	NNPS
cord-015935-r2wd1yfa	532	42	of	of	IN
cord-015935-r2wd1yfa	532	43	the	the	DT
cord-015935-r2wd1yfa	532	44	X	x	NN
cord-015935-r2wd1yfa	532	45	-	-	HYPH
cord-015935-r2wd1yfa	532	46	linked	link	VBN
cord-015935-r2wd1yfa	532	47	genes	gene	NNS
cord-015935-r2wd1yfa	532	48	encoding	encode	VBG
cord-015935-r2wd1yfa	532	49	neuroligins	neuroligins	NNP
cord-015935-r2wd1yfa	532	50	NLGN3	NLGN3	NNP
cord-015935-r2wd1yfa	533	1	and	and	CC
cord-015935-r2wd1yfa	533	2	NLGN4	nlgn4	NN
cord-015935-r2wd1yfa	533	3	are	be	VBP
cord-015935-r2wd1yfa	533	4	associated	associate	VBN
cord-015935-r2wd1yfa	533	5	with	with	IN
cord-015935-r2wd1yfa	533	6	autism	autism	NN
cord-015935-r2wd1yfa	533	7	Activated	activate	VBN
cord-015935-r2wd1yfa	533	8	mammalian	mammalian	JJ
cord-015935-r2wd1yfa	533	9	target	target	NN
cord-015935-r2wd1yfa	533	10	of	of	IN
cord-015935-r2wd1yfa	533	11	rapamycin	rapamycin	NN
cord-015935-r2wd1yfa	533	12	pathway	pathway	NN
cord-015935-r2wd1yfa	533	13	in	in	IN
cord-015935-r2wd1yfa	533	14	the	the	DT
cord-015935-r2wd1yfa	533	15	pathogenesis	pathogenesis	NN
cord-015935-r2wd1yfa	533	16	of	of	IN
cord-015935-r2wd1yfa	533	17	tuberous	tuberous	JJ
cord-015935-r2wd1yfa	533	18	sclerosis	sclerosis	NN
cord-015935-r2wd1yfa	533	19	complex	complex	JJ
cord-015935-r2wd1yfa	533	20	renal	renal	JJ
cord-015935-r2wd1yfa	533	21	tumors	tumor	NNS
cord-015935-r2wd1yfa	533	22	Human	human	JJ
cord-015935-r2wd1yfa	533	23	-	-	HYPH
cord-015935-r2wd1yfa	533	24	specific	specific	JJ
cord-015935-r2wd1yfa	533	25	transcriptional	transcriptional	JJ
cord-015935-r2wd1yfa	533	26	regulation	regulation	NN
cord-015935-r2wd1yfa	533	27	of	of	IN
cord-015935-r2wd1yfa	533	28	CNS	CNS	NNP
cord-015935-r2wd1yfa	533	29	development	development	NN
cord-015935-r2wd1yfa	533	30	genes	gene	NNS
cord-015935-r2wd1yfa	533	31	by	by	IN
cord-015935-r2wd1yfa	533	32	FOXP2	FOXP2	NNP
cord-015935-r2wd1yfa	533	33	Pten	Pten	NNP
cord-015935-r2wd1yfa	533	34	regulates	regulate	VBZ
cord-015935-r2wd1yfa	533	35	neuronal	neuronal	JJ
cord-015935-r2wd1yfa	533	36	arborization	arborization	NN
cord-015935-r2wd1yfa	533	37	and	and	CC
cord-015935-r2wd1yfa	533	38	social	social	JJ
cord-015935-r2wd1yfa	533	39	interaction	interaction	NN
cord-015935-r2wd1yfa	533	40	in	in	IN
cord-015935-r2wd1yfa	533	41	mice	mouse	NNS
cord-015935-r2wd1yfa	534	1	A	a	DT
cord-015935-r2wd1yfa	534	2	critical	critical	JJ
cord-015935-r2wd1yfa	534	3	analysis	analysis	NN
cord-015935-r2wd1yfa	534	4	of	of	IN
cord-015935-r2wd1yfa	534	5	new	new	JJ
cord-015935-r2wd1yfa	534	6	molecular	molecular	JJ
cord-015935-r2wd1yfa	534	7	targets	target	NNS
cord-015935-r2wd1yfa	534	8	and	and	CC
cord-015935-r2wd1yfa	534	9	strategies	strategy	NNS
cord-015935-r2wd1yfa	534	10	for	for	IN
cord-015935-r2wd1yfa	534	11	drug	drug	NN
cord-015935-r2wd1yfa	534	12	developments	development	NNS
cord-015935-r2wd1yfa	534	13	in	in	IN
cord-015935-r2wd1yfa	534	14	Alzheimer	Alzheimer	NNP
cord-015935-r2wd1yfa	534	15	's	's	POS
cord-015935-r2wd1yfa	534	16	disease	disease	NN
cord-015935-r2wd1yfa	535	1	The	the	DT
cord-015935-r2wd1yfa	535	2	LEARn	LEARn	NNP
cord-015935-r2wd1yfa	535	3	model	model	NN
cord-015935-r2wd1yfa	535	4	:	:	:
cord-015935-r2wd1yfa	536	1	An	an	DT
cord-015935-r2wd1yfa	536	2	epigenetic	epigenetic	JJ
cord-015935-r2wd1yfa	536	3	explanation	explanation	NN
cord-015935-r2wd1yfa	536	4	for	for	IN
cord-015935-r2wd1yfa	536	5	idiopathic	idiopathic	JJ
cord-015935-r2wd1yfa	536	6	neurobiological	neurobiological	JJ
cord-015935-r2wd1yfa	536	7	diseases	disease	NNS
cord-015935-r2wd1yfa	537	1	A	a	DT
cord-015935-r2wd1yfa	537	2	forkhead	forkhead	JJ
cord-015935-r2wd1yfa	537	3	-	-	HYPH
cord-015935-r2wd1yfa	537	4	domain	domain	NN
cord-015935-r2wd1yfa	537	5	gene	gene	NN
cord-015935-r2wd1yfa	537	6	is	be	VBZ
cord-015935-r2wd1yfa	537	7	mutated	mutate	VBN
cord-015935-r2wd1yfa	537	8	in	in	IN
cord-015935-r2wd1yfa	537	9	a	a	DT
cord-015935-r2wd1yfa	537	10	severe	severe	JJ
cord-015935-r2wd1yfa	537	11	speech	speech	NN
cord-015935-r2wd1yfa	537	12	and	and	CC
cord-015935-r2wd1yfa	537	13	language	language	NN
cord-015935-r2wd1yfa	537	14	disorder	disorder	NN
cord-015935-r2wd1yfa	537	15	Genetic	genetic	JJ
cord-015935-r2wd1yfa	537	16	dissection	dissection	NN
cord-015935-r2wd1yfa	537	17	of	of	IN
cord-015935-r2wd1yfa	537	18	complex	complex	JJ
cord-015935-r2wd1yfa	537	19	traits	trait	NNS
cord-015935-r2wd1yfa	537	20	:	:	:
cord-015935-r2wd1yfa	537	21	Guidelines	guideline	NNS
cord-015935-r2wd1yfa	537	22	for	for	IN
cord-015935-r2wd1yfa	537	23	interpreting	interpret	VBG
cord-015935-r2wd1yfa	537	24	and	and	CC
cord-015935-r2wd1yfa	537	25	reporting	report	VBG
cord-015935-r2wd1yfa	537	26	linkage	linkage	NN
cord-015935-r2wd1yfa	537	27	results	result	NNS
cord-015935-r2wd1yfa	538	1	Initial	initial	JJ
cord-015935-r2wd1yfa	538	2	sequencing	sequencing	NN
cord-015935-r2wd1yfa	538	3	and	and	CC
cord-015935-r2wd1yfa	538	4	analysis	analysis	NN
cord-015935-r2wd1yfa	538	5	of	of	IN
cord-015935-r2wd1yfa	538	6	the	the	DT
cord-015935-r2wd1yfa	538	7	human	human	JJ
cord-015935-r2wd1yfa	538	8	genome	genome	NN
cord-015935-r2wd1yfa	538	9	X	X	NNS
cord-015935-r2wd1yfa	538	10	-	-	HYPH
cord-015935-r2wd1yfa	538	11	linked	link	VBN
cord-015935-r2wd1yfa	538	12	mental	mental	JJ
cord-015935-r2wd1yfa	538	13	retardation	retardation	NN
cord-015935-r2wd1yfa	538	14	and	and	CC
cord-015935-r2wd1yfa	538	15	autism	autism	NN
cord-015935-r2wd1yfa	538	16	are	be	VBP
cord-015935-r2wd1yfa	538	17	associated	associate	VBN
cord-015935-r2wd1yfa	538	18	with	with	IN
cord-015935-r2wd1yfa	538	19	a	a	DT
cord-015935-r2wd1yfa	538	20	mutation	mutation	NN
cord-015935-r2wd1yfa	538	21	in	in	IN
cord-015935-r2wd1yfa	538	22	the	the	DT
cord-015935-r2wd1yfa	538	23	NLGN4	nlgn4	NN
cord-015935-r2wd1yfa	538	24	gene	gene	NN
cord-015935-r2wd1yfa	538	25	,	,	,
cord-015935-r2wd1yfa	538	26	a	a	DT
cord-015935-r2wd1yfa	538	27	member	member	NN
cord-015935-r2wd1yfa	538	28	of	of	IN
cord-015935-r2wd1yfa	538	29	the	the	DT
cord-015935-r2wd1yfa	538	30	neuroligin	neuroligin	NNP
cord-015935-r2wd1yfa	538	31	family	family	NN
cord-015935-r2wd1yfa	538	32	Familial	familial	JJ
cord-015935-r2wd1yfa	538	33	deletion	deletion	NN
cord-015935-r2wd1yfa	538	34	within	within	IN
cord-015935-r2wd1yfa	538	35	NLGN4	nlgn4	NN
cord-015935-r2wd1yfa	538	36	associated	associate	VBN
cord-015935-r2wd1yfa	538	37	with	with	IN
cord-015935-r2wd1yfa	538	38	autism	autism	NN
cord-015935-r2wd1yfa	538	39	and	and	CC
cord-015935-r2wd1yfa	538	40	Tourette	Tourette	NNP
cord-015935-r2wd1yfa	538	41	syndrome	syndrome	NN
cord-015935-r2wd1yfa	538	42	Clinical	clinical	JJ
cord-015935-r2wd1yfa	538	43	application	application	NN
cord-015935-r2wd1yfa	538	44	of	of	IN
cord-015935-r2wd1yfa	538	45	microarray	microarray	NN
cord-015935-r2wd1yfa	538	46	-	-	HYPH
cord-015935-r2wd1yfa	538	47	based	base	VBN
cord-015935-r2wd1yfa	538	48	molecular	molecular	JJ
cord-015935-r2wd1yfa	538	49	cytogenetics	cytogenetic	NNS
cord-015935-r2wd1yfa	538	50	:	:	:
cord-015935-r2wd1yfa	539	1	An	an	DT
cord-015935-r2wd1yfa	539	2	emerging	emerge	VBG
cord-015935-r2wd1yfa	539	3	new	new	JJ
cord-015935-r2wd1yfa	539	4	era	era	NN
cord-015935-r2wd1yfa	539	5	of	of	IN
cord-015935-r2wd1yfa	539	6	genomic	genomic	JJ
cord-015935-r2wd1yfa	539	7	medicine	medicine	NN
cord-015935-r2wd1yfa	539	8	Lack	lack	NN
cord-015935-r2wd1yfa	539	9	of	of	IN
cord-015935-r2wd1yfa	539	10	evidence	evidence	NN
cord-015935-r2wd1yfa	539	11	for	for	IN
cord-015935-r2wd1yfa	539	12	an	an	DT
cord-015935-r2wd1yfa	539	13	association	association	NN
cord-015935-r2wd1yfa	539	14	between	between	IN
cord-015935-r2wd1yfa	539	15	WNT2	WNT2	NNP
cord-015935-r2wd1yfa	539	16	and	and	CC
cord-015935-r2wd1yfa	539	17	RELN	RELN	NNP
cord-015935-r2wd1yfa	539	18	polymorphisms	polymorphism	NNS
cord-015935-r2wd1yfa	539	19	and	and	CC
cord-015935-r2wd1yfa	539	20	autism	autism	NN
cord-015935-r2wd1yfa	539	21	Cadherin	Cadherin	NNP
cord-015935-r2wd1yfa	539	22	-	-	HYPH
cord-015935-r2wd1yfa	539	23	catenin	catenin	NN
cord-015935-r2wd1yfa	539	24	proteins	protein	NNS
cord-015935-r2wd1yfa	539	25	in	in	IN
cord-015935-r2wd1yfa	539	26	vertebrate	vertebrate	JJ
cord-015935-r2wd1yfa	539	27	development	development	NN
cord-015935-r2wd1yfa	540	1	Autistic	autistic	JJ
cord-015935-r2wd1yfa	540	2	phenotypes	phenotype	NNS
cord-015935-r2wd1yfa	540	3	and	and	CC
cord-015935-r2wd1yfa	540	4	genetic	genetic	JJ
cord-015935-r2wd1yfa	540	5	testing	testing	NN
cord-015935-r2wd1yfa	540	6	:	:	:
cord-015935-r2wd1yfa	540	7	State	state	NN
cord-015935-r2wd1yfa	540	8	-	-	HYPH
cord-015935-r2wd1yfa	540	9	of	of	IN
cord-015935-r2wd1yfa	540	10	-	-	HYPH
cord-015935-r2wd1yfa	540	11	the	the	DT
cord-015935-r2wd1yfa	540	12	-	-	HYPH
cord-015935-r2wd1yfa	540	13	art	art	NN
cord-015935-r2wd1yfa	540	14	for	for	IN
cord-015935-r2wd1yfa	540	15	the	the	DT
cord-015935-r2wd1yfa	540	16	clinical	clinical	JJ
cord-015935-r2wd1yfa	540	17	geneticist	geneticist	NN
cord-015935-r2wd1yfa	540	18	Current	current	JJ
cord-015935-r2wd1yfa	540	19	developments	development	NNS
cord-015935-r2wd1yfa	540	20	in	in	IN
cord-015935-r2wd1yfa	540	21	the	the	DT
cord-015935-r2wd1yfa	540	22	genetics	genetic	NNS
cord-015935-r2wd1yfa	540	23	of	of	IN
cord-015935-r2wd1yfa	540	24	autism	autism	NN
cord-015935-r2wd1yfa	540	25	:	:	:
cord-015935-r2wd1yfa	541	1	From	from	IN
cord-015935-r2wd1yfa	541	2	phenome	phenome	NN
cord-015935-r2wd1yfa	541	3	to	to	TO
cord-015935-r2wd1yfa	541	4	genome	genome	VB
cord-015935-r2wd1yfa	541	5	A	a	DT
cord-015935-r2wd1yfa	541	6	marker	marker	NN
cord-015935-r2wd1yfa	541	7	X	x	NN
cord-015935-r2wd1yfa	541	8	chromosome	chromosome	NN
cord-015935-r2wd1yfa	541	9	Fragile	Fragile	NNP
cord-015935-r2wd1yfa	541	10	-	-	HYPH
cord-015935-r2wd1yfa	541	11	X	x	NN
cord-015935-r2wd1yfa	541	12	syndrome	syndrome	NN
cord-015935-r2wd1yfa	541	13	and	and	CC
cord-015935-r2wd1yfa	541	14	autism	autism	NN
cord-015935-r2wd1yfa	541	15	:	:	:
cord-015935-r2wd1yfa	541	16	A	a	DT
cord-015935-r2wd1yfa	541	17	prevalent	prevalent	JJ
cord-015935-r2wd1yfa	541	18	association	association	NN
cord-015935-r2wd1yfa	541	19	or	or	CC
cord-015935-r2wd1yfa	541	20	a	a	DT
cord-015935-r2wd1yfa	541	21	misinterpreted	misinterpret	VBN
cord-015935-r2wd1yfa	541	22	connection	connection	NN
cord-015935-r2wd1yfa	541	23	Neuropsychiatry	Neuropsychiatry	NNP
cord-015935-r2wd1yfa	541	24	of	of	IN
cord-015935-r2wd1yfa	541	25	18q	18q	CD
cord-015935-r2wd1yfa	541	26	Autism	autism	NN
cord-015935-r2wd1yfa	541	27	-	-	HYPH
cord-015935-r2wd1yfa	541	28	lessons	lesson	NNS
cord-015935-r2wd1yfa	541	29	from	from	IN
cord-015935-r2wd1yfa	541	30	the	the	DT
cord-015935-r2wd1yfa	541	31	X	x	NN
cord-015935-r2wd1yfa	541	32	chromosome	chromosome	NN
cord-015935-r2wd1yfa	541	33	Structural	structural	JJ
cord-015935-r2wd1yfa	541	34	variation	variation	NN
cord-015935-r2wd1yfa	541	35	of	of	IN
cord-015935-r2wd1yfa	541	36	chromosomes	chromosome	NNS
cord-015935-r2wd1yfa	541	37	in	in	IN
cord-015935-r2wd1yfa	541	38	autism	autism	NN
cord-015935-r2wd1yfa	541	39	spectrum	spectrum	NN
cord-015935-r2wd1yfa	541	40	disorder	disorder	NN
cord-015935-r2wd1yfa	542	1	Signaling	signal	VBG
cord-015935-r2wd1yfa	542	2	events	event	NNS
cord-015935-r2wd1yfa	542	3	regulating	regulate	VBG
cord-015935-r2wd1yfa	542	4	the	the	DT
cord-015935-r2wd1yfa	542	5	neurodevelopmental	neurodevelopmental	JJ
cord-015935-r2wd1yfa	542	6	triad	triad	NN
cord-015935-r2wd1yfa	542	7	.	.	.
cord-015935-r2wd1yfa	543	1	Glutamate	glutamate	NN
cord-015935-r2wd1yfa	543	2	and	and	CC
cord-015935-r2wd1yfa	543	3	secreted	secrete	VBN
cord-015935-r2wd1yfa	543	4	forms	form	NNS
cord-015935-r2wd1yfa	543	5	of	of	IN
cord-015935-r2wd1yfa	543	6	beta	beta	JJ
cord-015935-r2wd1yfa	543	7	-	-	HYPH
cord-015935-r2wd1yfa	543	8	amyloid	amyloid	NN
cord-015935-r2wd1yfa	543	9	precursor	precursor	NN
cord-015935-r2wd1yfa	543	10	protein	protein	NN
cord-015935-r2wd1yfa	543	11	as	as	IN
cord-015935-r2wd1yfa	543	12	examples	example	NNS
cord-015935-r2wd1yfa	543	13	Macrocephaly	Macrocephaly	NNP
cord-015935-r2wd1yfa	543	14	and	and	CC
cord-015935-r2wd1yfa	543	15	the	the	DT
cord-015935-r2wd1yfa	543	16	control	control	NN
cord-015935-r2wd1yfa	543	17	of	of	IN
cord-015935-r2wd1yfa	543	18	brain	brain	NN
cord-015935-r2wd1yfa	543	19	growth	growth	NN
cord-015935-r2wd1yfa	543	20	in	in	IN
cord-015935-r2wd1yfa	543	21	autistic	autistic	JJ
cord-015935-r2wd1yfa	543	22	disorders	disorder	NNS
cord-015935-r2wd1yfa	544	1	Genetic	genetic	JJ
cord-015935-r2wd1yfa	544	2	evaluation	evaluation	NN
cord-015935-r2wd1yfa	544	3	of	of	IN
cord-015935-r2wd1yfa	544	4	autism	autism	NN
cord-015935-r2wd1yfa	544	5	Contribution	Contribution	NNP
cord-015935-r2wd1yfa	544	6	of	of	IN
cord-015935-r2wd1yfa	544	7	SHANK3	SHANK3	NNP
cord-015935-r2wd1yfa	544	8	mutations	mutation	NNS
cord-015935-r2wd1yfa	544	9	to	to	IN
cord-015935-r2wd1yfa	544	10	autism	autism	NN
cord-015935-r2wd1yfa	544	11	spectrum	spectrum	NN
cord-015935-r2wd1yfa	544	12	disorder	disorder	NN
cord-015935-r2wd1yfa	544	13	Repetitive	repetitive	JJ
cord-015935-r2wd1yfa	544	14	and	and	CC
cord-015935-r2wd1yfa	544	15	stereotyped	stereotyped	JJ
cord-015935-r2wd1yfa	544	16	movements	movement	NNS
cord-015935-r2wd1yfa	544	17	in	in	IN
cord-015935-r2wd1yfa	544	18	children	child	NNS
cord-015935-r2wd1yfa	544	19	with	with	IN
cord-015935-r2wd1yfa	544	20	autism	autism	NN
cord-015935-r2wd1yfa	544	21	spectrum	spectrum	NN
cord-015935-r2wd1yfa	544	22	disorders	disorder	NNS
cord-015935-r2wd1yfa	544	23	late	late	RB
cord-015935-r2wd1yfa	544	24	in	in	IN
cord-015935-r2wd1yfa	544	25	the	the	DT
cord-015935-r2wd1yfa	544	26	second	second	JJ
cord-015935-r2wd1yfa	544	27	year	year	NN
cord-015935-r2wd1yfa	544	28	of	of	IN
cord-015935-r2wd1yfa	544	29	life	life	NN
cord-015935-r2wd1yfa	545	1	Identifying	identify	VBG
cord-015935-r2wd1yfa	545	2	autism	autism	NN
cord-015935-r2wd1yfa	545	3	loci	locus	NNS
cord-015935-r2wd1yfa	545	4	and	and	CC
cord-015935-r2wd1yfa	545	5	genes	gene	NNS
cord-015935-r2wd1yfa	545	6	by	by	IN
cord-015935-r2wd1yfa	545	7	tracing	trace	VBG
cord-015935-r2wd1yfa	545	8	recent	recent	JJ
cord-015935-r2wd1yfa	545	9	shared	share	VBN
cord-015935-r2wd1yfa	545	10	ancestry	ancestry	NN
cord-015935-r2wd1yfa	546	1	The	the	DT
cord-015935-r2wd1yfa	546	2	genetics	genetic	NNS
cord-015935-r2wd1yfa	546	3	of	of	IN
cord-015935-r2wd1yfa	546	4	autism	autism	NNP
cord-015935-r2wd1yfa	546	5	FOXP2	FOXP2	NNP
cord-015935-r2wd1yfa	546	6	is	be	VBZ
cord-015935-r2wd1yfa	546	7	not	not	RB
cord-015935-r2wd1yfa	546	8	a	a	DT
cord-015935-r2wd1yfa	546	9	major	major	JJ
cord-015935-r2wd1yfa	546	10	susceptibility	susceptibility	NN
cord-015935-r2wd1yfa	546	11	gene	gene	NN
cord-015935-r2wd1yfa	546	12	for	for	IN
cord-015935-r2wd1yfa	546	13	autism	autism	NN
cord-015935-r2wd1yfa	546	14	or	or	CC
cord-015935-r2wd1yfa	546	15	specific	specific	JJ
cord-015935-r2wd1yfa	546	16	language	language	NN
cord-015935-r2wd1yfa	546	17	impairment	impairment	NN
cord-015935-r2wd1yfa	546	18	Association	Association	NNP
cord-015935-r2wd1yfa	546	19	of	of	IN
cord-015935-r2wd1yfa	546	20	specific	specific	JJ
cord-015935-r2wd1yfa	546	21	language	language	NN
cord-015935-r2wd1yfa	546	22	impairment	impairment	NN
cord-015935-r2wd1yfa	546	23	(	(	-LRB-
cord-015935-r2wd1yfa	546	24	SLI	SLI	NNP
cord-015935-r2wd1yfa	546	25	)	)	-RRB-
cord-015935-r2wd1yfa	546	26	to	to	IN
cord-015935-r2wd1yfa	546	27	the	the	DT
cord-015935-r2wd1yfa	546	28	region	region	NN
cord-015935-r2wd1yfa	546	29	of	of	IN
cord-015935-r2wd1yfa	546	30	7q31	7q31	NNP
cord-015935-r2wd1yfa	546	31	Autism	Autism	NNP
cord-015935-r2wd1yfa	546	32	genetics	genetic	NNS
cord-015935-r2wd1yfa	546	33	:	:	:
cord-015935-r2wd1yfa	546	34	Strategies	strategy	NNS
cord-015935-r2wd1yfa	546	35	,	,	,
cord-015935-r2wd1yfa	546	36	challenges	challenge	NNS
cord-015935-r2wd1yfa	546	37	,	,	,
cord-015935-r2wd1yfa	546	38	and	and	CC
cord-015935-r2wd1yfa	546	39	opportunities	opportunity	NNS
cord-015935-r2wd1yfa	546	40	Diagnosing	diagnose	VBG
cord-015935-r2wd1yfa	546	41	learning	learn	VBG
cord-015935-r2wd1yfa	546	42	disorders	disorder	NNS
cord-015935-r2wd1yfa	546	43	:	:	:
cord-015935-r2wd1yfa	547	1	A	a	DT
cord-015935-r2wd1yfa	547	2	neuropsychological	neuropsychological	JJ
cord-015935-r2wd1yfa	547	3	framework	framework	NN
cord-015935-r2wd1yfa	547	4	Serotonin	Serotonin	NNP
cord-015935-r2wd1yfa	547	5	transporter	transporter	NN
cord-015935-r2wd1yfa	547	6	gene	gene	NN
cord-015935-r2wd1yfa	547	7	promoter	promoter	NN
cord-015935-r2wd1yfa	547	8	variants	variant	NNS
cord-015935-r2wd1yfa	547	9	do	do	VBP
cord-015935-r2wd1yfa	547	10	not	not	RB
cord-015935-r2wd1yfa	547	11	explain	explain	VB
cord-015935-r2wd1yfa	547	12	the	the	DT
cord-015935-r2wd1yfa	547	13	hyperserotonemia	hyperserotonemia	NN
cord-015935-r2wd1yfa	547	14	in	in	IN
cord-015935-r2wd1yfa	547	15	autistic	autistic	JJ
cord-015935-r2wd1yfa	547	16	children	child	NNS
cord-015935-r2wd1yfa	547	17	Latent	latent	NN
cord-015935-r2wd1yfa	547	18	-	-	HYPH
cord-015935-r2wd1yfa	547	19	class	class	NN
cord-015935-r2wd1yfa	547	20	analysis	analysis	NN
cord-015935-r2wd1yfa	547	21	of	of	IN
cord-015935-r2wd1yfa	547	22	recurrence	recurrence	NN
cord-015935-r2wd1yfa	547	23	risks	risk	NNS
cord-015935-r2wd1yfa	547	24	for	for	IN
cord-015935-r2wd1yfa	547	25	complex	complex	JJ
cord-015935-r2wd1yfa	547	26	phenotypes	phenotype	NNS
cord-015935-r2wd1yfa	547	27	with	with	IN
cord-015935-r2wd1yfa	547	28	selection	selection	NN
cord-015935-r2wd1yfa	547	29	and	and	CC
cord-015935-r2wd1yfa	547	30	measurement	measurement	NN
cord-015935-r2wd1yfa	547	31	error	error	NN
cord-015935-r2wd1yfa	547	32	:	:	:
cord-015935-r2wd1yfa	547	33	A	a	DT
cord-015935-r2wd1yfa	547	34	twin	twin	NN
cord-015935-r2wd1yfa	547	35	and	and	CC
cord-015935-r2wd1yfa	547	36	family	family	NN
cord-015935-r2wd1yfa	547	37	history	history	NN
cord-015935-r2wd1yfa	547	38	study	study	NN
cord-015935-r2wd1yfa	547	39	of	of	IN
cord-015935-r2wd1yfa	547	40	autism	autism	NN
cord-015935-r2wd1yfa	547	41	Genetic	genetic	JJ
cord-015935-r2wd1yfa	547	42	liability	liability	NN
cord-015935-r2wd1yfa	547	43	for	for	IN
cord-015935-r2wd1yfa	547	44	autism	autism	NN
cord-015935-r2wd1yfa	547	45	:	:	:
cord-015935-r2wd1yfa	547	46	The	the	DT
cord-015935-r2wd1yfa	547	47	behavioral	behavioral	JJ
cord-015935-r2wd1yfa	547	48	expression	expression	NN
cord-015935-r2wd1yfa	547	49	in	in	IN
cord-015935-r2wd1yfa	547	50	relatives	relative	NNS
cord-015935-r2wd1yfa	547	51	Advancing	advance	VBG
cord-015935-r2wd1yfa	547	52	paternal	paternal	JJ
cord-015935-r2wd1yfa	547	53	age	age	NN
cord-015935-r2wd1yfa	547	54	and	and	CC
cord-015935-r2wd1yfa	547	55	autism	autism	NN
cord-015935-r2wd1yfa	547	56	Genetic	genetic	JJ
cord-015935-r2wd1yfa	547	57	studies	study	NNS
cord-015935-r2wd1yfa	547	58	of	of	IN
cord-015935-r2wd1yfa	547	59	autism	autism	NN
cord-015935-r2wd1yfa	547	60	:	:	:
cord-015935-r2wd1yfa	547	61	From	from	IN
cord-015935-r2wd1yfa	547	62	the	the	DT
cord-015935-r2wd1yfa	547	63	1970s	1970	NNS
cord-015935-r2wd1yfa	547	64	into	into	IN
cord-015935-r2wd1yfa	547	65	the	the	DT
cord-015935-r2wd1yfa	547	66	millennium	millennium	NN
cord-015935-r2wd1yfa	547	67	Diagnostic	Diagnostic	NNP
cord-015935-r2wd1yfa	547	68	yield	yield	NN
cord-015935-r2wd1yfa	547	69	in	in	IN
cord-015935-r2wd1yfa	547	70	the	the	DT
cord-015935-r2wd1yfa	547	71	clinical	clinical	JJ
cord-015935-r2wd1yfa	547	72	genetics	genetics	NN
cord-015935-r2wd1yfa	547	73	evaluation	evaluation	NN
cord-015935-r2wd1yfa	547	74	of	of	IN
cord-015935-r2wd1yfa	547	75	autism	autism	NN
cord-015935-r2wd1yfa	547	76	spectrum	spectrum	NNP
cord-015935-r2wd1yfa	547	77	disorders	disorder	NNS
cord-015935-r2wd1yfa	547	78	Genetics	Genetics	NNP
cord-015935-r2wd1yfa	547	79	evaluation	evaluation	NN
cord-015935-r2wd1yfa	547	80	for	for	IN
cord-015935-r2wd1yfa	547	81	the	the	DT
cord-015935-r2wd1yfa	547	82	etiologic	etiologic	JJ
cord-015935-r2wd1yfa	547	83	diagnosis	diagnosis	NN
cord-015935-r2wd1yfa	547	84	of	of	IN
cord-015935-r2wd1yfa	547	85	autism	autism	NN
cord-015935-r2wd1yfa	547	86	spectrum	spectrum	NN
cord-015935-r2wd1yfa	547	87	disorders	disorder	NNS
cord-015935-r2wd1yfa	547	88	Clinical	clinical	JJ
cord-015935-r2wd1yfa	547	89	genetics	genetics	NN
cord-015935-r2wd1yfa	547	90	evaluation	evaluation	NN
cord-015935-r2wd1yfa	547	91	in	in	IN
cord-015935-r2wd1yfa	547	92	identifying	identify	VBG
cord-015935-r2wd1yfa	547	93	the	the	DT
cord-015935-r2wd1yfa	547	94	etiology	etiology	NN
cord-015935-r2wd1yfa	547	95	of	of	IN
cord-015935-r2wd1yfa	547	96	autism	autism	NN
cord-015935-r2wd1yfa	547	97	spectrum	spectrum	NN
cord-015935-r2wd1yfa	547	98	disorders	disorder	NNS
cord-015935-r2wd1yfa	547	99	Evidence	evidence	NN
cord-015935-r2wd1yfa	547	100	for	for	IN
cord-015935-r2wd1yfa	547	101	multiple	multiple	JJ
cord-015935-r2wd1yfa	547	102	loci	locus	NNS
cord-015935-r2wd1yfa	547	103	from	from	IN
cord-015935-r2wd1yfa	547	104	a	a	DT
cord-015935-r2wd1yfa	547	105	genome	genome	NN
cord-015935-r2wd1yfa	547	106	scan	scan	NN
cord-015935-r2wd1yfa	547	107	of	of	IN
cord-015935-r2wd1yfa	547	108	autism	autism	NN
cord-015935-r2wd1yfa	547	109	kindreds	kindreds	NNPS
cord-015935-r2wd1yfa	547	110	Autism	Autism	NNP
cord-015935-r2wd1yfa	547	111	and	and	CC
cord-015935-r2wd1yfa	547	112	maternally	maternally	RB
cord-015935-r2wd1yfa	547	113	derived	derive	VBN
cord-015935-r2wd1yfa	547	114	aberrations	aberration	NNS
cord-015935-r2wd1yfa	547	115	of	of	IN
cord-015935-r2wd1yfa	547	116	chromosome	chromosome	NN
cord-015935-r2wd1yfa	547	117	15q	15q	NNS
cord-015935-r2wd1yfa	548	1	Strong	Strong	NNP
cord-015935-r2wd1yfa	548	2	association	association	NNP
cord-015935-r2wd1yfa	548	3	of	of	IN
cord-015935-r2wd1yfa	548	4	de	de	NNP
cord-015935-r2wd1yfa	548	5	novo	novo	NNP
cord-015935-r2wd1yfa	548	6	copy	copy	NNP
cord-015935-r2wd1yfa	548	7	number	number	NN
cord-015935-r2wd1yfa	548	8	mutations	mutation	NNS
cord-015935-r2wd1yfa	548	9	with	with	IN
cord-015935-r2wd1yfa	548	10	autism	autism	NN
cord-015935-r2wd1yfa	548	11	Fine	fine	JJ
cord-015935-r2wd1yfa	548	12	mapping	mapping	NN
cord-015935-r2wd1yfa	548	13	of	of	IN
cord-015935-r2wd1yfa	548	14	autistic	autistic	JJ
cord-015935-r2wd1yfa	548	15	disorder	disorder	NN
cord-015935-r2wd1yfa	548	16	to	to	IN
cord-015935-r2wd1yfa	548	17	chromosome	chromosome	NN
cord-015935-r2wd1yfa	548	18	15q11-q13	15q11-q13	NN
cord-015935-r2wd1yfa	548	19	by	by	IN
cord-015935-r2wd1yfa	548	20	use	use	NN
cord-015935-r2wd1yfa	548	21	of	of	IN
cord-015935-r2wd1yfa	548	22	phenotypic	phenotypic	JJ
cord-015935-r2wd1yfa	548	23	subtypes	subtype	NNS
cord-015935-r2wd1yfa	549	1	A	a	DT
cord-015935-r2wd1yfa	549	2	genomewide	genomewide	NN
cord-015935-r2wd1yfa	549	3	scan	scan	NN
cord-015935-r2wd1yfa	549	4	identifies	identify	VBZ
cord-015935-r2wd1yfa	549	5	two	two	CD
cord-015935-r2wd1yfa	549	6	novel	novel	JJ
cord-015935-r2wd1yfa	549	7	loci	locus	NNS
cord-015935-r2wd1yfa	549	8	involved	involve	VBN
cord-015935-r2wd1yfa	549	9	in	in	IN
cord-015935-r2wd1yfa	549	10	specific	specific	JJ
cord-015935-r2wd1yfa	549	11	language	language	NN
cord-015935-r2wd1yfa	549	12	impairment	impairment	NN
cord-015935-r2wd1yfa	549	13	Highly	highly	RB
cord-015935-r2wd1yfa	549	14	significant	significant	JJ
cord-015935-r2wd1yfa	549	15	linkage	linkage	NN
cord-015935-r2wd1yfa	549	16	to	to	IN
cord-015935-r2wd1yfa	549	17	the	the	DT
cord-015935-r2wd1yfa	549	18	SLI1	SLI1	NNP
cord-015935-r2wd1yfa	549	19	locus	locus	NN
cord-015935-r2wd1yfa	549	20	in	in	IN
cord-015935-r2wd1yfa	549	21	an	an	DT
cord-015935-r2wd1yfa	549	22	expanded	expand	VBN
cord-015935-r2wd1yfa	549	23	sample	sample	NN
cord-015935-r2wd1yfa	549	24	of	of	IN
cord-015935-r2wd1yfa	549	25	individuals	individual	NNS
cord-015935-r2wd1yfa	549	26	affected	affect	VBN
cord-015935-r2wd1yfa	549	27	by	by	IN
cord-015935-r2wd1yfa	549	28	specific	specific	JJ
cord-015935-r2wd1yfa	549	29	language	language	NN
cord-015935-r2wd1yfa	549	30	impairment	impairment	NN
cord-015935-r2wd1yfa	549	31	Genes	gene	NNS
cord-015935-r2wd1yfa	549	32	,	,	,
cord-015935-r2wd1yfa	549	33	language	language	NN
cord-015935-r2wd1yfa	549	34	development	development	NN
cord-015935-r2wd1yfa	549	35	,	,	,
cord-015935-r2wd1yfa	549	36	and	and	CC
cord-015935-r2wd1yfa	549	37	language	language	NN
cord-015935-r2wd1yfa	549	38	disorders	disorder	NNS
cord-015935-r2wd1yfa	549	39	High	high	JJ
cord-015935-r2wd1yfa	549	40	levels	level	NNS
cord-015935-r2wd1yfa	549	41	of	of	IN
cord-015935-r2wd1yfa	549	42	Alzheimer	Alzheimer	NNP
cord-015935-r2wd1yfa	549	43	beta	beta	NN
cord-015935-r2wd1yfa	549	44	-	-	HYPH
cord-015935-r2wd1yfa	549	45	amyloid	amyloid	NN
cord-015935-r2wd1yfa	549	46	precursor	precursor	NN
cord-015935-r2wd1yfa	549	47	protein	protein	NN
cord-015935-r2wd1yfa	549	48	(	(	-LRB-
cord-015935-r2wd1yfa	549	49	APP	app	NN
cord-015935-r2wd1yfa	549	50	)	)	-RRB-
cord-015935-r2wd1yfa	549	51	in	in	IN
cord-015935-r2wd1yfa	549	52	children	child	NNS
cord-015935-r2wd1yfa	549	53	with	with	IN
cord-015935-r2wd1yfa	549	54	severely	severely	RB
cord-015935-r2wd1yfa	549	55	autistic	autistic	JJ
cord-015935-r2wd1yfa	549	56	behavior	behavior	NN
cord-015935-r2wd1yfa	549	57	and	and	CC
cord-015935-r2wd1yfa	549	58	aggression	aggression	NN
cord-015935-r2wd1yfa	549	59	Neuroimaging	neuroimaging	NN
cord-015935-r2wd1yfa	549	60	in	in	IN
cord-015935-r2wd1yfa	549	61	autistic	autistic	JJ
cord-015935-r2wd1yfa	549	62	spectrum	spectrum	NN
cord-015935-r2wd1yfa	549	63	disorder	disorder	NN
cord-015935-r2wd1yfa	550	1	(	(	-LRB-
cord-015935-r2wd1yfa	550	2	ASD	ASD	NNP
cord-015935-r2wd1yfa	550	3	)	)	-RRB-
cord-015935-r2wd1yfa	550	4	Brain	Brain	NNP
cord-015935-r2wd1yfa	550	5	structural	structural	JJ
cord-015935-r2wd1yfa	550	6	abnormalities	abnormality	NNS
cord-015935-r2wd1yfa	550	7	in	in	IN
cord-015935-r2wd1yfa	550	8	young	young	JJ
cord-015935-r2wd1yfa	550	9	children	child	NNS
cord-015935-r2wd1yfa	550	10	with	with	IN
cord-015935-r2wd1yfa	550	11	autism	autism	NN
cord-015935-r2wd1yfa	550	12	spectrum	spectrum	NN
cord-015935-r2wd1yfa	550	13	disorder	disorder	NN
cord-015935-r2wd1yfa	551	1	A	a	DT
cord-015935-r2wd1yfa	551	2	twin	twin	JJ
cord-015935-r2wd1yfa	551	3	study	study	NN
cord-015935-r2wd1yfa	551	4	of	of	IN
cord-015935-r2wd1yfa	551	5	autism	autism	NN
cord-015935-r2wd1yfa	551	6	in	in	IN
cord-015935-r2wd1yfa	551	7	Denmark	Denmark	NNP
cord-015935-r2wd1yfa	551	8	Language	Language	NNP
cord-015935-r2wd1yfa	551	9	-	-	HYPH
cord-015935-r2wd1yfa	551	10	impaired	impair	VBN
cord-015935-r2wd1yfa	551	11	preschoolers	preschooler	NNS
cord-015935-r2wd1yfa	551	12	:	:	:
cord-015935-r2wd1yfa	552	1	A	a	DT
cord-015935-r2wd1yfa	552	2	followup	followup	NN
cord-015935-r2wd1yfa	552	3	into	into	IN
cord-015935-r2wd1yfa	552	4	adolescence	adolescence	NN
cord-015935-r2wd1yfa	552	5	Recessive	recessive	JJ
cord-015935-r2wd1yfa	552	6	symptomatic	symptomatic	JJ
cord-015935-r2wd1yfa	552	7	focal	focal	JJ
cord-015935-r2wd1yfa	552	8	epilepsy	epilepsy	NN
cord-015935-r2wd1yfa	552	9	and	and	CC
cord-015935-r2wd1yfa	552	10	mutant	mutant	JJ
cord-015935-r2wd1yfa	552	11	contactin	contactin	NN
cord-015935-r2wd1yfa	552	12	-	-	HYPH
cord-015935-r2wd1yfa	552	13	associated	associate	VBN
cord-015935-r2wd1yfa	552	14	protein	protein	NN
cord-015935-r2wd1yfa	552	15	-	-	HYPH
cord-015935-r2wd1yfa	552	16	like	like	JJ
cord-015935-r2wd1yfa	552	17	2	2	CD
cord-015935-r2wd1yfa	552	18	Autism	autism	NN
cord-015935-r2wd1yfa	552	19	:	:	:
cord-015935-r2wd1yfa	552	20	The	the	DT
cord-015935-r2wd1yfa	552	21	quest	quest	NN
cord-015935-r2wd1yfa	552	22	for	for	IN
cord-015935-r2wd1yfa	552	23	the	the	DT
cord-015935-r2wd1yfa	552	24	genes	gene	NNS
cord-015935-r2wd1yfa	552	25	Mapping	Mapping	NNP
cord-015935-r2wd1yfa	552	26	autism	autism	NN
cord-015935-r2wd1yfa	552	27	risk	risk	NN
cord-015935-r2wd1yfa	552	28	loci	locus	NNS
cord-015935-r2wd1yfa	552	29	using	use	VBG
cord-015935-r2wd1yfa	552	30	genetic	genetic	JJ
cord-015935-r2wd1yfa	552	31	linkage	linkage	NN
cord-015935-r2wd1yfa	552	32	and	and	CC
cord-015935-r2wd1yfa	552	33	chromosomal	chromosomal	JJ
cord-015935-r2wd1yfa	552	34	rearrangements	rearrangement	NNS
cord-015935-r2wd1yfa	552	35	Ethical	ethical	JJ
cord-015935-r2wd1yfa	552	36	implications	implication	NNS
cord-015935-r2wd1yfa	552	37	of	of	IN
cord-015935-r2wd1yfa	552	38	array	array	NN
cord-015935-r2wd1yfa	552	39	comparative	comparative	JJ
cord-015935-r2wd1yfa	552	40	genomic	genomic	JJ
cord-015935-r2wd1yfa	552	41	hybridization	hybridization	NN
cord-015935-r2wd1yfa	552	42	in	in	IN
cord-015935-r2wd1yfa	552	43	complex	complex	JJ
cord-015935-r2wd1yfa	552	44	phenotypes	phenotype	NNS
cord-015935-r2wd1yfa	552	45	:	:	:
cord-015935-r2wd1yfa	552	46	Points	point	NNS
cord-015935-r2wd1yfa	552	47	to	to	TO
cord-015935-r2wd1yfa	552	48	consider	consider	VB
cord-015935-r2wd1yfa	552	49	in	in	IN
cord-015935-r2wd1yfa	552	50	research	research	NN
cord-015935-r2wd1yfa	552	51	Prevalence	prevalence	NN
cord-015935-r2wd1yfa	552	52	of	of	IN
cord-015935-r2wd1yfa	552	53	specific	specific	JJ
cord-015935-r2wd1yfa	552	54	language	language	NN
cord-015935-r2wd1yfa	552	55	impairment	impairment	NN
cord-015935-r2wd1yfa	552	56	in	in	IN
cord-015935-r2wd1yfa	552	57	kindergarten	kindergarten	NN
cord-015935-r2wd1yfa	552	58	children	child	NNS
cord-015935-r2wd1yfa	552	59	Molecular	molecular	JJ
cord-015935-r2wd1yfa	552	60	genetics	genetic	NNS
cord-015935-r2wd1yfa	552	61	of	of	IN
cord-015935-r2wd1yfa	552	62	autism	autism	NN
cord-015935-r2wd1yfa	552	63	spectrum	spectrum	NN
cord-015935-r2wd1yfa	552	64	disorder	disorder	NN
cord-015935-r2wd1yfa	553	1	The	the	DT
cord-015935-r2wd1yfa	553	2	RAY1	RAY1	NNP
cord-015935-r2wd1yfa	553	3	/	/	SYM
cord-015935-r2wd1yfa	553	4	ST7	st7	JJ
cord-015935-r2wd1yfa	553	5	tumor	tumor	NN
cord-015935-r2wd1yfa	553	6	-	-	HYPH
cord-015935-r2wd1yfa	553	7	suppressor	suppressor	NN
cord-015935-r2wd1yfa	553	8	locus	locus	NN
cord-015935-r2wd1yfa	553	9	on	on	IN
cord-015935-r2wd1yfa	553	10	chromosome	chromosome	NN
cord-015935-r2wd1yfa	553	11	7q31	7q31	CD
cord-015935-r2wd1yfa	553	12	represents	represent	VBZ
cord-015935-r2wd1yfa	553	13	a	a	DT
cord-015935-r2wd1yfa	553	14	complex	complex	JJ
cord-015935-r2wd1yfa	553	15	multi	multi	JJ
cord-015935-r2wd1yfa	553	16	-	-	JJ
cord-015935-r2wd1yfa	553	17	transcript	transcript	JJ
cord-015935-r2wd1yfa	553	18	system	system	NN
cord-015935-r2wd1yfa	553	19	Neurology	Neurology	NNP
cord-015935-r2wd1yfa	553	20	of	of	IN
cord-015935-r2wd1yfa	553	21	the	the	DT
cord-015935-r2wd1yfa	553	22	newborn	newborn	JJ
cord-015935-r2wd1yfa	553	23	Identification	identification	NN
cord-015935-r2wd1yfa	553	24	of	of	IN
cord-015935-r2wd1yfa	553	25	novel	novel	JJ
cord-015935-r2wd1yfa	553	26	autism	autism	NN
cord-015935-r2wd1yfa	553	27	candidate	candidate	NN
cord-015935-r2wd1yfa	553	28	regions	region	NNS
cord-015935-r2wd1yfa	553	29	through	through	IN
cord-015935-r2wd1yfa	553	30	analysis	analysis	NN
cord-015935-r2wd1yfa	553	31	of	of	IN
cord-015935-r2wd1yfa	553	32	reported	reported	JJ
cord-015935-r2wd1yfa	553	33	cytogenetic	cytogenetic	JJ
cord-015935-r2wd1yfa	553	34	abnormalities	abnormality	NNS
cord-015935-r2wd1yfa	553	35	associated	associate	VBN
cord-015935-r2wd1yfa	553	36	with	with	IN
cord-015935-r2wd1yfa	553	37	autism	autism	NN
cord-015935-r2wd1yfa	554	1	The	the	DT
cord-015935-r2wd1yfa	554	2	search	search	NN
cord-015935-r2wd1yfa	554	3	for	for	IN
cord-015935-r2wd1yfa	554	4	autism	autism	NN
cord-015935-r2wd1yfa	554	5	disease	disease	NN
cord-015935-r2wd1yfa	554	6	genes	gene	NNS
cord-015935-r2wd1yfa	555	1	Evidence	evidence	NN
cord-015935-r2wd1yfa	555	2	supporting	support	VBG
cord-015935-r2wd1yfa	555	3	WNT2	WNT2	NNP
cord-015935-r2wd1yfa	555	4	as	as	IN
cord-015935-r2wd1yfa	555	5	an	an	DT
cord-015935-r2wd1yfa	555	6	autism	autism	NN
cord-015935-r2wd1yfa	555	7	susceptibility	susceptibility	NN
cord-015935-r2wd1yfa	555	8	gene	gene	NN
cord-015935-r2wd1yfa	555	9	A	a	DT
cord-015935-r2wd1yfa	555	10	genome	genome	NN
cord-015935-r2wd1yfa	555	11	-	-	HYPH
cord-015935-r2wd1yfa	555	12	wide	wide	JJ
cord-015935-r2wd1yfa	555	13	linkage	linkage	NN
cord-015935-r2wd1yfa	555	14	and	and	CC
cord-015935-r2wd1yfa	555	15	association	association	NN
cord-015935-r2wd1yfa	555	16	scan	scan	NN
cord-015935-r2wd1yfa	555	17	reveals	reveal	VBZ
cord-015935-r2wd1yfa	555	18	novel	novel	JJ
cord-015935-r2wd1yfa	555	19	loci	locus	NNS
cord-015935-r2wd1yfa	555	20	for	for	IN
cord-015935-r2wd1yfa	555	21	autism	autism	NN
cord-015935-r2wd1yfa	555	22	FMRP	FMRP	NNP
cord-015935-r2wd1yfa	555	23	mediates	mediate	VBZ
cord-015935-r2wd1yfa	555	24	mGluR5-dependent	mGluR5-dependent	NNP
cord-015935-r2wd1yfa	555	25	translation	translation	NN
cord-015935-r2wd1yfa	555	26	of	of	IN
cord-015935-r2wd1yfa	555	27	amyloid	amyloid	NN
cord-015935-r2wd1yfa	555	28	precursor	precursor	NN
cord-015935-r2wd1yfa	555	29	protein	protein	NN
cord-015935-r2wd1yfa	555	30	Analysis	Analysis	NNP
cord-015935-r2wd1yfa	555	31	of	of	IN
cord-015935-r2wd1yfa	555	32	the	the	DT
cord-015935-r2wd1yfa	555	33	neuroligin	neuroligin	NNP
cord-015935-r2wd1yfa	555	34	3	3	CD
cord-015935-r2wd1yfa	555	35	and	and	CC
cord-015935-r2wd1yfa	555	36	4	4	CD
cord-015935-r2wd1yfa	555	37	genes	gene	NNS
cord-015935-r2wd1yfa	555	38	in	in	IN
cord-015935-r2wd1yfa	555	39	autism	autism	NN
cord-015935-r2wd1yfa	555	40	and	and	CC
cord-015935-r2wd1yfa	555	41	other	other	JJ
cord-015935-r2wd1yfa	555	42	neuropsychiatric	neuropsychiatric	JJ
cord-015935-r2wd1yfa	555	43	patients	patient	NNS
cord-015935-r2wd1yfa	555	44	Reelin	Reelin	NNP
cord-015935-r2wd1yfa	555	45	gene	gene	NN
cord-015935-r2wd1yfa	555	46	alleles	allele	NNS
cord-015935-r2wd1yfa	555	47	and	and	CC
cord-015935-r2wd1yfa	555	48	susceptibility	susceptibility	NN
cord-015935-r2wd1yfa	555	49	to	to	IN
cord-015935-r2wd1yfa	555	50	autism	autism	NN
cord-015935-r2wd1yfa	555	51	spectrum	spectrum	NN
cord-015935-r2wd1yfa	555	52	disorders	disorder	NNS
cord-015935-r2wd1yfa	555	53	Postnatal	postnatal	JJ
cord-015935-r2wd1yfa	555	54	neurodevelopmental	neurodevelopmental	JJ
cord-015935-r2wd1yfa	555	55	disorders	disorder	NNS
cord-015935-r2wd1yfa	555	56	:	:	:
cord-015935-r2wd1yfa	556	1	Meeting	meet	VBG
cord-015935-r2wd1yfa	556	2	at	at	IN
cord-015935-r2wd1yfa	556	3	the	the	DT
cord-015935-r2wd1yfa	556	4	synapse	synapse	NN
cord-015935-r2wd1yfa	556	5	?	?	.
cord-015935-r2wd1yfa	557	1	Science	Science	NNP
cord-015935-r2wd1yfa	557	2	Acknowledgment	Acknowledgment	NNP
cord-015935-r2wd1yfa	558	1	Thanks	thank	NNS
cord-015935-r2wd1yfa	558	2	to	to	IN
cord-015935-r2wd1yfa	558	3	Bryan	Bryan	NNP
cord-015935-r2wd1yfa	558	4	Maloney	Maloney	NNP
cord-015935-r2wd1yfa	558	5	,	,	,
cord-015935-r2wd1yfa	558	6	M.S.	M.S.	NNP
cord-015935-r2wd1yfa	558	7	for	for	IN
cord-015935-r2wd1yfa	558	8	his	-PRON-	PRP$
cord-015935-r2wd1yfa	558	9	help	help	NN
cord-015935-r2wd1yfa	558	10	in	in	IN
cord-015935-r2wd1yfa	558	11	editing	edit	VBG
cord-015935-r2wd1yfa	558	12	this	this	DT
cord-015935-r2wd1yfa	558	13	manuscript	manuscript	NN
cord-015935-r2wd1yfa	558	14	.	.	.