id	sid	tid	token	lemma	pos
cord-009615-xcz8m9a7	1	1	key	key	NN
cord-009615-xcz8m9a7	1	2	:	:	:
cord-009615-xcz8m9a7	2	1	cord-009615-xcz8m9a7	cord-009615-xcz8m9a7	NN
cord-009615-xcz8m9a7	2	2	authors	author	NNS
cord-009615-xcz8m9a7	2	3	:	:	:
cord-009615-xcz8m9a7	2	4	Stoner	Stoner	NNP
cord-009615-xcz8m9a7	2	5	,	,	,
cord-009615-xcz8m9a7	2	6	Gerald	Gerald	NNP
cord-009615-xcz8m9a7	2	7	L.	L.	NNP
cord-009615-xcz8m9a7	2	8	title	title	NN
cord-009615-xcz8m9a7	2	9	:	:	:
cord-009615-xcz8m9a7	2	10	Polyomavirus	Polyomavirus	NNP
cord-009615-xcz8m9a7	2	11	Models	Models	NNPS
cord-009615-xcz8m9a7	2	12	of	of	IN
cord-009615-xcz8m9a7	2	13	Brain	Brain	NNP
cord-009615-xcz8m9a7	2	14	Infection	Infection	NNP
cord-009615-xcz8m9a7	2	15	and	and	CC
cord-009615-xcz8m9a7	2	16	the	the	DT
cord-009615-xcz8m9a7	2	17	Pathogenesis	Pathogenesis	NNP
cord-009615-xcz8m9a7	2	18	of	of	IN
cord-009615-xcz8m9a7	2	19	Multiple	Multiple	NNP
cord-009615-xcz8m9a7	2	20	Sclerosis	Sclerosis	NNP
cord-009615-xcz8m9a7	2	21	date	date	NN
cord-009615-xcz8m9a7	2	22	:	:	:
cord-009615-xcz8m9a7	2	23	2008	2008	CD
cord-009615-xcz8m9a7	2	24	-	-	SYM
cord-009615-xcz8m9a7	2	25	01	01	CD
cord-009615-xcz8m9a7	2	26	-	-	HYPH
cord-009615-xcz8m9a7	2	27	28	28	CD
cord-009615-xcz8m9a7	2	28	journal	journal	NN
cord-009615-xcz8m9a7	2	29	:	:	:
cord-009615-xcz8m9a7	3	1	Brain	Brain	NNP
cord-009615-xcz8m9a7	3	2	Pathol	Pathol	NNP
cord-009615-xcz8m9a7	3	3	DOI	DOI	NNP
cord-009615-xcz8m9a7	3	4	:	:	:
cord-009615-xcz8m9a7	4	1	10.1111	10.1111	CD
cord-009615-xcz8m9a7	4	2	/	/	SYM
cord-009615-xcz8m9a7	4	3	j.1750	j.1750	NNP
cord-009615-xcz8m9a7	4	4	-	-	HYPH
cord-009615-xcz8m9a7	4	5	3639.1993.tb00748.x	3639.1993.tb00748.x	CD
cord-009615-xcz8m9a7	4	6	sha	sha	NNP
cord-009615-xcz8m9a7	4	7	:	:	:
cord-009615-xcz8m9a7	4	8	4909f165f53715b3512cf7a9d9ae4c050da5cb96	4909f165f53715b3512cf7a9d9ae4c050da5cb96	CD
cord-009615-xcz8m9a7	4	9	doc_id	doc_id	CD
cord-009615-xcz8m9a7	4	10	:	:	:
cord-009615-xcz8m9a7	4	11	9615	9615	CD
cord-009615-xcz8m9a7	4	12	cord_uid	cord_uid	NNS
cord-009615-xcz8m9a7	4	13	:	:	:
cord-009615-xcz8m9a7	5	1	xcz8m9a7	xcz8m9a7	NNP
cord-009615-xcz8m9a7	6	1	Multiple	multiple	JJ
cord-009615-xcz8m9a7	6	2	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	6	3	(	(	-LRB-
cord-009615-xcz8m9a7	6	4	MS	MS	NNP
cord-009615-xcz8m9a7	6	5	)	)	-RRB-
cord-009615-xcz8m9a7	6	6	is	be	VBZ
cord-009615-xcz8m9a7	6	7	generally	generally	RB
cord-009615-xcz8m9a7	6	8	considered	consider	VBN
cord-009615-xcz8m9a7	6	9	to	to	TO
cord-009615-xcz8m9a7	6	10	be	be	VB
cord-009615-xcz8m9a7	6	11	an	an	DT
cord-009615-xcz8m9a7	6	12	autoimmune	autoimmune	JJ
cord-009615-xcz8m9a7	6	13	disorder	disorder	NN
cord-009615-xcz8m9a7	6	14	with	with	IN
cord-009615-xcz8m9a7	6	15	myelin	myelin	NN
cord-009615-xcz8m9a7	6	16	as	as	IN
cord-009615-xcz8m9a7	6	17	the	the	DT
cord-009615-xcz8m9a7	6	18	target	target	NN
cord-009615-xcz8m9a7	6	19	and	and	CC
cord-009615-xcz8m9a7	6	20	with	with	IN
cord-009615-xcz8m9a7	6	21	several	several	JJ
cord-009615-xcz8m9a7	6	22	unidentified	unidentified	JJ
cord-009615-xcz8m9a7	6	23	viruses	virus	NNS
cord-009615-xcz8m9a7	6	24	playing	play	VBG
cord-009615-xcz8m9a7	6	25	ancillary	ancillary	JJ
cord-009615-xcz8m9a7	6	26	roles	role	NNS
cord-009615-xcz8m9a7	6	27	,	,	,
cord-009615-xcz8m9a7	6	28	possibly	possibly	RB
cord-009615-xcz8m9a7	6	29	through	through	IN
cord-009615-xcz8m9a7	6	30	molecular	molecular	JJ
cord-009615-xcz8m9a7	6	31	mimicry	mimicry	NN
cord-009615-xcz8m9a7	6	32	.	.	.
cord-009615-xcz8m9a7	7	1	Although	although	IN
cord-009615-xcz8m9a7	7	2	this	this	DT
cord-009615-xcz8m9a7	7	3	paradigm	paradigm	NN
cord-009615-xcz8m9a7	7	4	has	have	VBZ
cord-009615-xcz8m9a7	7	5	led	lead	VBN
cord-009615-xcz8m9a7	7	6	to	to	IN
cord-009615-xcz8m9a7	7	7	important	important	JJ
cord-009615-xcz8m9a7	7	8	progress	progress	NN
cord-009615-xcz8m9a7	7	9	on	on	IN
cord-009615-xcz8m9a7	7	10	potential	potential	JJ
cord-009615-xcz8m9a7	7	11	mechanisms	mechanism	NNS
cord-009615-xcz8m9a7	7	12	of	of	IN
cord-009615-xcz8m9a7	7	13	myelin	myelin	JJ
cord-009615-xcz8m9a7	7	14	loss	loss	NN
cord-009615-xcz8m9a7	7	15	,	,	,
cord-009615-xcz8m9a7	7	16	neither	neither	CC
cord-009615-xcz8m9a7	7	17	a	a	DT
cord-009615-xcz8m9a7	7	18	target	target	NN
cord-009615-xcz8m9a7	7	19	antigen	antigen	NN
cord-009615-xcz8m9a7	7	20	in	in	IN
cord-009615-xcz8m9a7	7	21	myelin	myelin	NN
cord-009615-xcz8m9a7	7	22	nor	nor	CC
cord-009615-xcz8m9a7	7	23	a	a	DT
cord-009615-xcz8m9a7	7	24	triggering	trigger	VBG
cord-009615-xcz8m9a7	7	25	mechanism	mechanism	NN
cord-009615-xcz8m9a7	7	26	has	have	VBZ
cord-009615-xcz8m9a7	7	27	yet	yet	RB
cord-009615-xcz8m9a7	7	28	been	be	VBN
cord-009615-xcz8m9a7	7	29	identified	identify	VBN
cord-009615-xcz8m9a7	7	30	,	,	,
cord-009615-xcz8m9a7	7	31	leaving	leave	VBG
cord-009615-xcz8m9a7	7	32	the	the	DT
cord-009615-xcz8m9a7	7	33	etiology	etiology	NN
cord-009615-xcz8m9a7	7	34	of	of	IN
cord-009615-xcz8m9a7	7	35	MS	MS	NNP
cord-009615-xcz8m9a7	7	36	still	still	RB
cord-009615-xcz8m9a7	7	37	unknown	unknown	JJ
cord-009615-xcz8m9a7	7	38	.	.	.
cord-009615-xcz8m9a7	8	1	Animal	animal	NN
cord-009615-xcz8m9a7	8	2	models	model	NNS
cord-009615-xcz8m9a7	8	3	of	of	IN
cord-009615-xcz8m9a7	8	4	viral	viral	JJ
cord-009615-xcz8m9a7	8	5	demyelination	demyelination	NN
cord-009615-xcz8m9a7	8	6	and	and	CC
cord-009615-xcz8m9a7	8	7	studies	study	NNS
cord-009615-xcz8m9a7	8	8	showing	show	VBG
cord-009615-xcz8m9a7	8	9	that	that	IN
cord-009615-xcz8m9a7	8	10	JC	JC	NNP
cord-009615-xcz8m9a7	8	11	virus	virus	NN
cord-009615-xcz8m9a7	8	12	(	(	-LRB-
cord-009615-xcz8m9a7	8	13	JCV	JCV	NNP
cord-009615-xcz8m9a7	8	14	)	)	-RRB-
cord-009615-xcz8m9a7	8	15	,	,	,
cord-009615-xcz8m9a7	8	16	the	the	DT
cord-009615-xcz8m9a7	8	17	polyomavirus	polyomavirus	NNP
cord-009615-xcz8m9a7	8	18	which	which	WDT
cord-009615-xcz8m9a7	8	19	causes	cause	VBZ
cord-009615-xcz8m9a7	8	20	progressive	progressive	JJ
cord-009615-xcz8m9a7	8	21	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	8	22	leukoencephalopathy	leukoencephalopathy	NNS
cord-009615-xcz8m9a7	8	23	(	(	-LRB-
cord-009615-xcz8m9a7	8	24	PML	PML	NNP
cord-009615-xcz8m9a7	8	25	)	)	-RRB-
cord-009615-xcz8m9a7	8	26	,	,	,
cord-009615-xcz8m9a7	8	27	may	may	MD
cord-009615-xcz8m9a7	8	28	be	be	VB
cord-009615-xcz8m9a7	8	29	latent	latent	JJ
cord-009615-xcz8m9a7	8	30	in	in	IN
cord-009615-xcz8m9a7	8	31	some	some	DT
cord-009615-xcz8m9a7	8	32	normal	normal	JJ
cord-009615-xcz8m9a7	8	33	human	human	JJ
cord-009615-xcz8m9a7	8	34	brains	brain	NNS
cord-009615-xcz8m9a7	8	35	suggest	suggest	VBP
cord-009615-xcz8m9a7	8	36	another	another	DT
cord-009615-xcz8m9a7	8	37	possibility	possibility	NN
cord-009615-xcz8m9a7	8	38	.	.	.
cord-009615-xcz8m9a7	9	1	A	a	DT
cord-009615-xcz8m9a7	9	2	host	host	NN
cord-009615-xcz8m9a7	9	3	immune	immune	JJ
cord-009615-xcz8m9a7	9	4	response	response	NN
cord-009615-xcz8m9a7	9	5	targeting	target	VBG
cord-009615-xcz8m9a7	9	6	proteins	protein	NNS
cord-009615-xcz8m9a7	9	7	expressed	express	VBN
cord-009615-xcz8m9a7	9	8	at	at	IN
cord-009615-xcz8m9a7	9	9	low	low	JJ
cord-009615-xcz8m9a7	9	10	levels	level	NNS
cord-009615-xcz8m9a7	9	11	from	from	IN
cord-009615-xcz8m9a7	9	12	viral	viral	JJ
cord-009615-xcz8m9a7	9	13	DNA	dna	NN
cord-009615-xcz8m9a7	9	14	latent	latent	NN
cord-009615-xcz8m9a7	9	15	in	in	IN
cord-009615-xcz8m9a7	9	16	the	the	DT
cord-009615-xcz8m9a7	9	17	central	central	JJ
cord-009615-xcz8m9a7	9	18	nervous	nervous	JJ
cord-009615-xcz8m9a7	9	19	system	system	NN
cord-009615-xcz8m9a7	9	20	(	(	-LRB-
cord-009615-xcz8m9a7	9	21	CNS	CNS	NNP
cord-009615-xcz8m9a7	9	22	)	)	-RRB-
cord-009615-xcz8m9a7	9	23	might	may	MD
cord-009615-xcz8m9a7	9	24	underlie	underlie	VB
cord-009615-xcz8m9a7	9	25	a	a	DT
cord-009615-xcz8m9a7	9	26	focal	focal	JJ
cord-009615-xcz8m9a7	9	27	demyelinating	demyelinate	VBG
cord-009615-xcz8m9a7	9	28	disease	disease	NN
cord-009615-xcz8m9a7	9	29	such	such	JJ
cord-009615-xcz8m9a7	9	30	as	as	IN
cord-009615-xcz8m9a7	9	31	MS	MS	NNP
cord-009615-xcz8m9a7	9	32	.	.	.
cord-009615-xcz8m9a7	10	1	A	a	DT
cord-009615-xcz8m9a7	10	2	shift	shift	NN
cord-009615-xcz8m9a7	10	3	from	from	IN
cord-009615-xcz8m9a7	10	4	autoimmunity	autoimmunity	NN
cord-009615-xcz8m9a7	10	5	to	to	IN
cord-009615-xcz8m9a7	10	6	a	a	DT
cord-009615-xcz8m9a7	10	7	latent‐virus	latent‐virus	NNP
cord-009615-xcz8m9a7	10	8	model	model	NN
cord-009615-xcz8m9a7	10	9	is	be	VBZ
cord-009615-xcz8m9a7	10	10	not	not	RB
cord-009615-xcz8m9a7	10	11	a	a	DT
cord-009615-xcz8m9a7	10	12	trivial	trivial	JJ
cord-009615-xcz8m9a7	10	13	substitution	substitution	NN
cord-009615-xcz8m9a7	10	14	of	of	IN
cord-009615-xcz8m9a7	10	15	target	target	NN
cord-009615-xcz8m9a7	10	16	antigens	antigen	NNS
cord-009615-xcz8m9a7	10	17	.	.	.
cord-009615-xcz8m9a7	11	1	This	this	DT
cord-009615-xcz8m9a7	11	2	shift	shift	NN
cord-009615-xcz8m9a7	11	3	would	would	MD
cord-009615-xcz8m9a7	11	4	expand	expand	VB
cord-009615-xcz8m9a7	11	5	the	the	DT
cord-009615-xcz8m9a7	11	6	search	search	NN
cord-009615-xcz8m9a7	11	7	for	for	IN
cord-009615-xcz8m9a7	11	8	a	a	DT
cord-009615-xcz8m9a7	11	9	definitive	definitive	JJ
cord-009615-xcz8m9a7	11	10	laboratory	laboratory	NN
cord-009615-xcz8m9a7	11	11	test	test	NN
cord-009615-xcz8m9a7	11	12	for	for	IN
cord-009615-xcz8m9a7	11	13	MS	MS	NNP
cord-009615-xcz8m9a7	11	14	and	and	CC
cord-009615-xcz8m9a7	11	15	could	could	MD
cord-009615-xcz8m9a7	11	16	lead	lead	VB
cord-009615-xcz8m9a7	11	17	to	to	IN
cord-009615-xcz8m9a7	11	18	improved	improve	VBN
cord-009615-xcz8m9a7	11	19	therapeutic	therapeutic	JJ
cord-009615-xcz8m9a7	11	20	and	and	CC
cord-009615-xcz8m9a7	11	21	preventive	preventive	JJ
cord-009615-xcz8m9a7	11	22	approaches	approach	NNS
cord-009615-xcz8m9a7	11	23	.	.	.
cord-009615-xcz8m9a7	12	1	For	for	IN
cord-009615-xcz8m9a7	12	2	more	more	JJR
cord-009615-xcz8m9a7	12	3	than	than	IN
cord-009615-xcz8m9a7	12	4	25	25	CD
cord-009615-xcz8m9a7	12	5	years	year	NNS
cord-009615-xcz8m9a7	12	6	the	the	DT
cord-009615-xcz8m9a7	12	7	autoimmune	autoimmune	JJ
cord-009615-xcz8m9a7	12	8	theory	theory	NN
cord-009615-xcz8m9a7	12	9	of	of	IN
cord-009615-xcz8m9a7	12	10	multiple	multiple	JJ
cord-009615-xcz8m9a7	12	11	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	12	12	(	(	-LRB-
cord-009615-xcz8m9a7	12	13	MS	MS	NNP
cord-009615-xcz8m9a7	12	14	)	)	-RRB-
cord-009615-xcz8m9a7	12	15	etiology	etiology	NN
cord-009615-xcz8m9a7	12	16	has	have	VBZ
cord-009615-xcz8m9a7	12	17	dominated	dominate	VBN
cord-009615-xcz8m9a7	12	18	the	the	DT
cord-009615-xcz8m9a7	12	19	field	field	NN
cord-009615-xcz8m9a7	12	20	.	.	.
cord-009615-xcz8m9a7	13	1	The	the	DT
cord-009615-xcz8m9a7	13	2	origins	origin	NNS
cord-009615-xcz8m9a7	13	3	of	of	IN
cord-009615-xcz8m9a7	13	4	the	the	DT
cord-009615-xcz8m9a7	13	5	experimental	experimental	JJ
cord-009615-xcz8m9a7	13	6	allergic	allergic	JJ
cord-009615-xcz8m9a7	13	7	encephalomyelitis	encephalomyelitis	NN
cord-009615-xcz8m9a7	13	8	(	(	-LRB-
cord-009615-xcz8m9a7	13	9	EAE	EAE	NNP
cord-009615-xcz8m9a7	13	10	)	)	-RRB-
cord-009615-xcz8m9a7	13	11	/	/	NFP
cord-009615-xcz8m9a7	13	12	autoimmunity	autoimmunity	NN
cord-009615-xcz8m9a7	13	13	paradigm	paradigm	NN
cord-009615-xcz8m9a7	13	14	go	go	VBP
cord-009615-xcz8m9a7	13	15	back	back	RB
cord-009615-xcz8m9a7	13	16	nearly	nearly	RB
cord-009615-xcz8m9a7	13	17	60	60	CD
cord-009615-xcz8m9a7	13	18	years	year	NNS
cord-009615-xcz8m9a7	13	19	to	to	IN
cord-009615-xcz8m9a7	13	20	the	the	DT
cord-009615-xcz8m9a7	13	21	work	work	NN
cord-009615-xcz8m9a7	13	22	of	of	IN
cord-009615-xcz8m9a7	13	23	Rivers	Rivers	NNPS
cord-009615-xcz8m9a7	13	24	and	and	CC
cord-009615-xcz8m9a7	13	25	colleagues	colleague	NNS
cord-009615-xcz8m9a7	13	26	on	on	IN
cord-009615-xcz8m9a7	13	27	demyelination	demyelination	NN
cord-009615-xcz8m9a7	13	28	following	follow	VBG
cord-009615-xcz8m9a7	13	29	repeated	repeat	VBN
cord-009615-xcz8m9a7	13	30	injections	injection	NNS
cord-009615-xcz8m9a7	13	31	of	of	IN
cord-009615-xcz8m9a7	13	32	normal	normal	JJ
cord-009615-xcz8m9a7	13	33	rabbit	rabbit	NN
cord-009615-xcz8m9a7	13	34	brain	brain	NN
cord-009615-xcz8m9a7	13	35	homogenate	homogenate	NNP
cord-009615-xcz8m9a7	13	36	into	into	IN
cord-009615-xcz8m9a7	13	37	monkeys	monkey	NNS
cord-009615-xcz8m9a7	13	38	(	(	-LRB-
cord-009615-xcz8m9a7	13	39	1	1	CD
cord-009615-xcz8m9a7	13	40	)	)	-RRB-
cord-009615-xcz8m9a7	13	41	.	.	.
cord-009615-xcz8m9a7	14	1	Despite	despite	IN
cord-009615-xcz8m9a7	14	2	occasional	occasional	JJ
cord-009615-xcz8m9a7	14	3	dissent	dissent	NN
cord-009615-xcz8m9a7	14	4	by	by	IN
cord-009615-xcz8m9a7	14	5	some	some	DT
cord-009615-xcz8m9a7	14	6	neuropathologists	neuropathologist	NNS
cord-009615-xcz8m9a7	14	7	(	(	-LRB-
cord-009615-xcz8m9a7	14	8	2	2	CD
cord-009615-xcz8m9a7	14	9	-	-	SYM
cord-009615-xcz8m9a7	14	10	4	4	CD
cord-009615-xcz8m9a7	14	11	)	)	-RRB-
cord-009615-xcz8m9a7	14	12	,	,	,
cord-009615-xcz8m9a7	14	13	EAE	EAE	NNP
cord-009615-xcz8m9a7	14	14	has	have	VBZ
cord-009615-xcz8m9a7	14	15	generally	generally	RB
cord-009615-xcz8m9a7	14	16	been	be	VBN
cord-009615-xcz8m9a7	14	17	considered	consider	VBN
cord-009615-xcz8m9a7	14	18	to	to	TO
cord-009615-xcz8m9a7	14	19	have	have	VB
cord-009615-xcz8m9a7	14	20	sufficient	sufficient	JJ
cord-009615-xcz8m9a7	14	21	clinical	clinical	JJ
cord-009615-xcz8m9a7	14	22	and	and	CC
cord-009615-xcz8m9a7	14	23	pathological	pathological	JJ
cord-009615-xcz8m9a7	14	24	similari	similari	JJ
cord-009615-xcz8m9a7	14	25	-	-	HYPH
cord-009615-xcz8m9a7	14	26	ties	tie	NNS
cord-009615-xcz8m9a7	14	27	to	to	IN
cord-009615-xcz8m9a7	14	28	MS	MS	NNP
cord-009615-xcz8m9a7	14	29	to	to	TO
cord-009615-xcz8m9a7	14	30	provide	provide	VB
cord-009615-xcz8m9a7	14	31	a	a	DT
cord-009615-xcz8m9a7	14	32	valid	valid	JJ
cord-009615-xcz8m9a7	14	33	model	model	NN
cord-009615-xcz8m9a7	14	34	.	.	.
cord-009615-xcz8m9a7	15	1	Development	development	NN
cord-009615-xcz8m9a7	15	2	of	of	IN
cord-009615-xcz8m9a7	15	3	the	the	DT
cord-009615-xcz8m9a7	15	4	chronic	chronic	NN
cord-009615-xcz8m9a7	15	5	-	-	HYPH
cord-009615-xcz8m9a7	15	6	relapsing	relapse	VBG
cord-009615-xcz8m9a7	15	7	variant	variant	NN
cord-009615-xcz8m9a7	15	8	of	of	IN
cord-009615-xcz8m9a7	15	9	experimental	experimental	JJ
cord-009615-xcz8m9a7	15	10	allergic	allergic	JJ
cord-009615-xcz8m9a7	15	11	encephalomyelitis	encephalomyelitis	NN
cord-009615-xcz8m9a7	15	12	(	(	-LRB-
cord-009615-xcz8m9a7	15	13	CR	CR	NNP
cord-009615-xcz8m9a7	15	14	-	-	HYPH
cord-009615-xcz8m9a7	15	15	EAE	EAE	NNP
cord-009615-xcz8m9a7	15	16	)	)	-RRB-
cord-009615-xcz8m9a7	15	17	added	add	VBD
cord-009615-xcz8m9a7	15	18	to	to	IN
cord-009615-xcz8m9a7	15	19	the	the	DT
cord-009615-xcz8m9a7	15	20	utility	utility	NN
cord-009615-xcz8m9a7	15	21	of	of	IN
cord-009615-xcz8m9a7	15	22	this	this	DT
cord-009615-xcz8m9a7	15	23	model	model	NN
cord-009615-xcz8m9a7	15	24	(	(	-LRB-
cord-009615-xcz8m9a7	15	25	5,6	5,6	CD
cord-009615-xcz8m9a7	15	26	)	)	-RRB-
cord-009615-xcz8m9a7	15	27	.	.	.
cord-009615-xcz8m9a7	16	1	Over	over	IN
cord-009615-xcz8m9a7	16	2	the	the	DT
cord-009615-xcz8m9a7	16	3	years	year	NNS
cord-009615-xcz8m9a7	16	4	,	,	,
cord-009615-xcz8m9a7	16	5	increasingly	increasingly	RB
cord-009615-xcz8m9a7	16	6	sophisticated	sophisticated	JJ
cord-009615-xcz8m9a7	16	7	immunological	immunological	JJ
cord-009615-xcz8m9a7	16	8	approaches	approach	NNS
cord-009615-xcz8m9a7	16	9	have	have	VBP
cord-009615-xcz8m9a7	16	10	dissected	dissect	VBN
cord-009615-xcz8m9a7	16	11	all	all	DT
cord-009615-xcz8m9a7	16	12	aspects	aspect	NNS
cord-009615-xcz8m9a7	16	13	of	of	IN
cord-009615-xcz8m9a7	16	14	the	the	DT
cord-009615-xcz8m9a7	16	15	EAE	EAE	NNP
cord-009615-xcz8m9a7	16	16	model	model	NN
cord-009615-xcz8m9a7	16	17	,	,	,
cord-009615-xcz8m9a7	16	18	as	as	RB
cord-009615-xcz8m9a7	16	19	well	well	RB
cord-009615-xcz8m9a7	16	20	as	as	IN
cord-009615-xcz8m9a7	16	21	the	the	DT
cord-009615-xcz8m9a7	16	22	immune	immune	JJ
cord-009615-xcz8m9a7	16	23	dysregulation	dysregulation	NN
cord-009615-xcz8m9a7	16	24	evident	evident	JJ
cord-009615-xcz8m9a7	16	25	in	in	IN
cord-009615-xcz8m9a7	16	26	MS	MS	NNP
cord-009615-xcz8m9a7	16	27	(	(	-LRB-
cord-009615-xcz8m9a7	16	28	7	7	CD
cord-009615-xcz8m9a7	16	29	)	)	-RRB-
cord-009615-xcz8m9a7	16	30	(	(	-LRB-
cord-009615-xcz8m9a7	16	31	8)	8)	NNP
cord-009615-xcz8m9a7	16	32	(	(	-LRB-
cord-009615-xcz8m9a7	16	33	9	9	CD
cord-009615-xcz8m9a7	16	34	)	)	-RRB-
cord-009615-xcz8m9a7	16	35	(	(	-LRB-
cord-009615-xcz8m9a7	16	36	10	10	CD
cord-009615-xcz8m9a7	16	37	)	)	-RRB-
cord-009615-xcz8m9a7	16	38	(	(	-LRB-
cord-009615-xcz8m9a7	16	39	11	11	CD
cord-009615-xcz8m9a7	16	40	)	)	-RRB-
cord-009615-xcz8m9a7	16	41	(	(	-LRB-
cord-009615-xcz8m9a7	16	42	12	12	CD
cord-009615-xcz8m9a7	16	43	)	)	-RRB-
cord-009615-xcz8m9a7	16	44	(	(	-LRB-
cord-009615-xcz8m9a7	16	45	13	13	CD
cord-009615-xcz8m9a7	16	46	)	)	-RRB-
cord-009615-xcz8m9a7	16	47	(	(	-LRB-
cord-009615-xcz8m9a7	16	48	14	14	CD
cord-009615-xcz8m9a7	16	49	)	)	-RRB-
cord-009615-xcz8m9a7	16	50	(	(	-LRB-
cord-009615-xcz8m9a7	16	51	15	15	CD
cord-009615-xcz8m9a7	16	52	)	)	-RRB-
cord-009615-xcz8m9a7	16	53	)	)	-RRB-
cord-009615-xcz8m9a7	16	54	.	.	.
cord-009615-xcz8m9a7	17	1	However	however	RB
cord-009615-xcz8m9a7	17	2	,	,	,
cord-009615-xcz8m9a7	17	3	while	while	IN
cord-009615-xcz8m9a7	17	4	T	t	NN
cord-009615-xcz8m9a7	17	5	cells	cell	NNS
cord-009615-xcz8m9a7	17	6	specific	specific	JJ
cord-009615-xcz8m9a7	17	7	for	for	IN
cord-009615-xcz8m9a7	17	8	myelin	myelin	JJ
cord-009615-xcz8m9a7	17	9	basic	basic	JJ
cord-009615-xcz8m9a7	17	10	protein	protein	NN
cord-009615-xcz8m9a7	17	11	(	(	-LRB-
cord-009615-xcz8m9a7	17	12	MBP	MBP	NNP
cord-009615-xcz8m9a7	17	13	)	)	-RRB-
cord-009615-xcz8m9a7	17	14	can	can	MD
cord-009615-xcz8m9a7	17	15	be	be	VB
cord-009615-xcz8m9a7	17	16	found	find	VBN
cord-009615-xcz8m9a7	17	17	in	in	IN
cord-009615-xcz8m9a7	17	18	the	the	DT
cord-009615-xcz8m9a7	17	19	circulation	circulation	NN
cord-009615-xcz8m9a7	17	20	of	of	IN
cord-009615-xcz8m9a7	17	21	MS	MS	NNP
cord-009615-xcz8m9a7	17	22	patients	patient	NNS
cord-009615-xcz8m9a7	17	23	,	,	,
cord-009615-xcz8m9a7	17	24	similar	similar	JJ
cord-009615-xcz8m9a7	17	25	cells	cell	NNS
cord-009615-xcz8m9a7	17	26	can	can	MD
cord-009615-xcz8m9a7	17	27	be	be	VB
cord-009615-xcz8m9a7	17	28	demonstrated	demonstrate	VBN
cord-009615-xcz8m9a7	17	29	in	in	IN
cord-009615-xcz8m9a7	17	30	healthy	healthy	JJ
cord-009615-xcz8m9a7	17	31	individuals	individual	NNS
cord-009615-xcz8m9a7	17	32	as	as	RB
cord-009615-xcz8m9a7	17	33	well	well	RB
cord-009615-xcz8m9a7	17	34	(	(	-LRB-
cord-009615-xcz8m9a7	17	35	9,16	9,16	CD
cord-009615-xcz8m9a7	17	36	-	-	SYM
cord-009615-xcz8m9a7	17	37	21	21	CD
cord-009615-xcz8m9a7	17	38	)	)	-RRB-
cord-009615-xcz8m9a7	17	39	.	.	.
cord-009615-xcz8m9a7	18	1	Thus	thus	RB
cord-009615-xcz8m9a7	18	2	,	,	,
cord-009615-xcz8m9a7	18	3	questions	question	NNS
cord-009615-xcz8m9a7	18	4	persist	persist	VBP
cord-009615-xcz8m9a7	18	5	about	about	IN
cord-009615-xcz8m9a7	18	6	the	the	DT
cord-009615-xcz8m9a7	18	7	significance	significance	NN
cord-009615-xcz8m9a7	18	8	of	of	IN
cord-009615-xcz8m9a7	18	9	these	these	DT
cord-009615-xcz8m9a7	18	10	immunological	immunological	JJ
cord-009615-xcz8m9a7	18	11	abnormalities	abnormality	NNS
cord-009615-xcz8m9a7	18	12	and	and	CC
cord-009615-xcz8m9a7	18	13	anti	anti	JJ
cord-009615-xcz8m9a7	18	14	-	-	JJ
cord-009615-xcz8m9a7	18	15	myelin	myelin	JJ
cord-009615-xcz8m9a7	18	16	reactivities	reactivity	NNS
cord-009615-xcz8m9a7	18	17	,	,	,
cord-009615-xcz8m9a7	18	18	some	some	DT
cord-009615-xcz8m9a7	18	19	of	of	IN
cord-009615-xcz8m9a7	18	20	which	which	WDT
cord-009615-xcz8m9a7	18	21	might	may	MD
cord-009615-xcz8m9a7	18	22	be	be	VB
cord-009615-xcz8m9a7	18	23	a	a	DT
cord-009615-xcz8m9a7	18	24	reflection	reflection	NN
cord-009615-xcz8m9a7	18	25	of	of	IN
cord-009615-xcz8m9a7	18	26	natural	natural	JJ
cord-009615-xcz8m9a7	18	27	immunity	immunity	NN
cord-009615-xcz8m9a7	18	28	or	or	CC
cord-009615-xcz8m9a7	18	29	epiphenomena	epiphenomenon	NNS
cord-009615-xcz8m9a7	18	30	resulting	result	VBG
cord-009615-xcz8m9a7	18	31	from	from	IN
cord-009615-xcz8m9a7	18	32	myelin	myelin	NN
cord-009615-xcz8m9a7	18	33	breakdown	breakdown	NN
cord-009615-xcz8m9a7	18	34	,	,	,
cord-009615-xcz8m9a7	18	35	rather	rather	RB
cord-009615-xcz8m9a7	18	36	than	than	IN
cord-009615-xcz8m9a7	18	37	its	-PRON-	PRP$
cord-009615-xcz8m9a7	18	38	cause	cause	NN
cord-009615-xcz8m9a7	18	39	(	(	-LRB-
cord-009615-xcz8m9a7	18	40	7	7	CD
cord-009615-xcz8m9a7	18	41	,	,	,
cord-009615-xcz8m9a7	18	42	2225	2225	CD
cord-009615-xcz8m9a7	18	43	)	)	-RRB-
cord-009615-xcz8m9a7	18	44	.	.	.
cord-009615-xcz8m9a7	19	1	Other	other	JJ
cord-009615-xcz8m9a7	19	2	immunological	immunological	JJ
cord-009615-xcz8m9a7	19	3	abnormalities	abnormality	NNS
cord-009615-xcz8m9a7	19	4	might	may	MD
cord-009615-xcz8m9a7	19	5	be	be	VB
cord-009615-xcz8m9a7	19	6	secondary	secondary	JJ
cord-009615-xcz8m9a7	19	7	to	to	IN
cord-009615-xcz8m9a7	19	8	virus	virus	NN
cord-009615-xcz8m9a7	19	9	recrudescence	recrudescence	NNP
cord-009615-xcz8m9a7	19	10	(	(	-LRB-
cord-009615-xcz8m9a7	19	11	26	26	CD
cord-009615-xcz8m9a7	19	12	)	)	-RRB-
cord-009615-xcz8m9a7	19	13	.	.	.
cord-009615-xcz8m9a7	20	1	A	a	DT
cord-009615-xcz8m9a7	20	2	recent	recent	JJ
cord-009615-xcz8m9a7	20	3	report	report	NN
cord-009615-xcz8m9a7	20	4	of	of	IN
cord-009615-xcz8m9a7	20	5	the	the	DT
cord-009615-xcz8m9a7	20	6	development	development	NN
cord-009615-xcz8m9a7	20	7	of	of	IN
cord-009615-xcz8m9a7	20	8	white	white	JJ
cord-009615-xcz8m9a7	20	9	matter	matter	NN
cord-009615-xcz8m9a7	20	10	1e:;ions	1e:;ions	CD
cord-009615-xcz8m9a7	20	11	in	in	IN
cord-009615-xcz8m9a7	20	12	severe	severe	JJ
cord-009615-xcz8m9a7	20	13	combined	combine	VBN
cord-009615-xcz8m9a7	20	14	immunodeficiency	immunodeficiency	NN
cord-009615-xcz8m9a7	21	1	(	(	-LRB-
cord-009615-xcz8m9a7	21	2	SCID	SCID	NNP
cord-009615-xcz8m9a7	21	3	)	)	-RRB-
cord-009615-xcz8m9a7	21	4	mice	mouse	NNS
cord-009615-xcz8m9a7	21	5	following	follow	VBG
cord-009615-xcz8m9a7	21	6	intracisternal	intracisternal	JJ
cord-009615-xcz8m9a7	21	7	injection	injection	NN
cord-009615-xcz8m9a7	21	8	of	of	IN
cord-009615-xcz8m9a7	21	9	CSF	CSF	NNP
cord-009615-xcz8m9a7	21	10	mononuclear	mononuclear	NN
cord-009615-xcz8m9a7	21	11	cells	cell	NNS
cord-009615-xcz8m9a7	21	12	from	from	IN
cord-009615-xcz8m9a7	21	13	MS	MS	NNP
cord-009615-xcz8m9a7	21	14	patients	patient	NNS
cord-009615-xcz8m9a7	21	15	in	in	IN
cord-009615-xcz8m9a7	21	16	exacerbation	exacerbation	NN
cord-009615-xcz8m9a7	21	17	(	(	-LRB-
cord-009615-xcz8m9a7	21	18	27	27	CD
cord-009615-xcz8m9a7	21	19	)	)	-RRB-
cord-009615-xcz8m9a7	21	20	supports	support	VBZ
cord-009615-xcz8m9a7	21	21	a	a	DT
cord-009615-xcz8m9a7	21	22	pathogenetic	pathogenetic	JJ
cord-009615-xcz8m9a7	21	23	role	role	NN
cord-009615-xcz8m9a7	21	24	for	for	IN
cord-009615-xcz8m9a7	21	25	these	these	DT
cord-009615-xcz8m9a7	21	26	cells	cell	NNS
cord-009615-xcz8m9a7	21	27	,	,	,
cord-009615-xcz8m9a7	21	28	but	but	CC
cord-009615-xcz8m9a7	21	29	their	-PRON-	PRP$
cord-009615-xcz8m9a7	21	30	antigen	antigen	NN
cord-009615-xcz8m9a7	21	31	specificity	specificity	NN
cord-009615-xcz8m9a7	21	32	,	,	,
cord-009615-xcz8m9a7	21	33	if	if	IN
cord-009615-xcz8m9a7	21	34	any	any	DT
cord-009615-xcz8m9a7	21	35	,	,	,
cord-009615-xcz8m9a7	21	36	remains	remain	VBZ
cord-009615-xcz8m9a7	21	37	undefined	undefined	JJ
cord-009615-xcz8m9a7	21	38	.	.	.
cord-009615-xcz8m9a7	22	1	Experimentally	experimentally	RB
cord-009615-xcz8m9a7	22	2	,	,	,
cord-009615-xcz8m9a7	22	3	viral	viral	JJ
cord-009615-xcz8m9a7	22	4	concepts	concept	NNS
cord-009615-xcz8m9a7	22	5	of	of	IN
cord-009615-xcz8m9a7	22	6	MS	MS	NNP
cord-009615-xcz8m9a7	22	7	etiopathogenesis	etiopathogenesis	NNP
cord-009615-xcz8m9a7	22	8	owe	owe	VBP
cord-009615-xcz8m9a7	22	9	much	much	JJ
cord-009615-xcz8m9a7	22	10	to	to	IN
cord-009615-xcz8m9a7	22	11	the	the	DT
cord-009615-xcz8m9a7	22	12	elegant	elegant	JJ
cord-009615-xcz8m9a7	22	13	studies	study	NNS
cord-009615-xcz8m9a7	22	14	of	of	IN
cord-009615-xcz8m9a7	22	15	demyelination	demyelination	NN
cord-009615-xcz8m9a7	22	16	mediated	mediate	VBN
cord-009615-xcz8m9a7	22	17	by	by	IN
cord-009615-xcz8m9a7	22	18	the	the	DT
cord-009615-xcz8m9a7	22	19	immune	immune	JJ
cord-009615-xcz8m9a7	22	20	response	response	NN
cord-009615-xcz8m9a7	22	21	to	to	IN
cord-009615-xcz8m9a7	22	22	viral	viral	JJ
cord-009615-xcz8m9a7	22	23	gene	gene	NN
cord-009615-xcz8m9a7	22	24	products	product	NNS
cord-009615-xcz8m9a7	22	25	delineated	delineate	VBN
cord-009615-xcz8m9a7	22	26	in	in	IN
cord-009615-xcz8m9a7	22	27	the	the	DT
cord-009615-xcz8m9a7	22	28	Theiler	Theiler	NNP
cord-009615-xcz8m9a7	22	29	's	's	POS
cord-009615-xcz8m9a7	22	30	murine	murine	JJ
cord-009615-xcz8m9a7	22	31	encephalomyelitis	encephalomyelitis	NN
cord-009615-xcz8m9a7	22	32	virus	virus	NN
cord-009615-xcz8m9a7	22	33	(	(	-LRB-
cord-009615-xcz8m9a7	22	34	TMEV	TMEV	NNP
cord-009615-xcz8m9a7	22	35	)	)	-RRB-
cord-009615-xcz8m9a7	22	36	model	model	NN
cord-009615-xcz8m9a7	22	37	(	(	-LRB-
cord-009615-xcz8m9a7	22	38	28	28	CD
cord-009615-xcz8m9a7	22	39	)	)	-RRB-
cord-009615-xcz8m9a7	22	40	.	.	.
cord-009615-xcz8m9a7	23	1	However	however	RB
cord-009615-xcz8m9a7	23	2	,	,	,
cord-009615-xcz8m9a7	23	3	reports	report	NNS
cord-009615-xcz8m9a7	23	4	of	of	IN
cord-009615-xcz8m9a7	23	5	a	a	DT
cord-009615-xcz8m9a7	23	6	variety	variety	NN
cord-009615-xcz8m9a7	23	7	of	of	IN
cord-009615-xcz8m9a7	23	8	candidate	candidate	NN
cord-009615-xcz8m9a7	23	9	MS	MS	NNP
cord-009615-xcz8m9a7	23	10	viruses	virus	NNS
cord-009615-xcz8m9a7	23	11	isolated	isolate	VBN
cord-009615-xcz8m9a7	23	12	from	from	IN
cord-009615-xcz8m9a7	23	13	the	the	DT
cord-009615-xcz8m9a7	23	14	human	human	JJ
cord-009615-xcz8m9a7	23	15	brain	brain	NN
cord-009615-xcz8m9a7	23	16	have	have	VBP
cord-009615-xcz8m9a7	23	17	remained	remain	VBN
cord-009615-xcz8m9a7	23	18	largely	largely	RB
cord-009615-xcz8m9a7	23	19	unconfirmed	unconfirmed	JJ
cord-009615-xcz8m9a7	23	20	in	in	IN
cord-009615-xcz8m9a7	23	21	other	other	JJ
cord-009615-xcz8m9a7	23	22	laboratories	laboratory	NNS
cord-009615-xcz8m9a7	23	23	(	(	-LRB-
cord-009615-xcz8m9a7	23	24	29	29	CD
cord-009615-xcz8m9a7	23	25	)	)	-RRB-
cord-009615-xcz8m9a7	23	26	,	,	,
cord-009615-xcz8m9a7	23	27	and	and	CC
cord-009615-xcz8m9a7	23	28	an	an	DT
cord-009615-xcz8m9a7	23	29	appropriate	appropriate	JJ
cord-009615-xcz8m9a7	23	30	viral	viral	JJ
cord-009615-xcz8m9a7	23	31	model	model	NN
cord-009615-xcz8m9a7	23	32	involving	involve	VBG
cord-009615-xcz8m9a7	23	33	latency	latency	NN
cord-009615-xcz8m9a7	23	34	and	and	CC
cord-009615-xcz8m9a7	23	35	reactivation	reactivation	NN
cord-009615-xcz8m9a7	23	36	of	of	IN
cord-009615-xcz8m9a7	23	37	a	a	DT
cord-009615-xcz8m9a7	23	38	human	human	JJ
cord-009615-xcz8m9a7	23	39	virus	virus	NN
cord-009615-xcz8m9a7	23	40	in	in	IN
cord-009615-xcz8m9a7	23	41	glial	glial	JJ
cord-009615-xcz8m9a7	23	42	cells	cell	NNS
cord-009615-xcz8m9a7	23	43	has	have	VBZ
cord-009615-xcz8m9a7	23	44	been	be	VBN
cord-009615-xcz8m9a7	23	45	lacking	lack	VBG
cord-009615-xcz8m9a7	23	46	.	.	.
cord-009615-xcz8m9a7	24	1	More	more	RBR
cord-009615-xcz8m9a7	24	2	recently	recently	RB
cord-009615-xcz8m9a7	24	3	,	,	,
cord-009615-xcz8m9a7	24	4	the	the	DT
cord-009615-xcz8m9a7	24	5	molecular	molecular	JJ
cord-009615-xcz8m9a7	24	6	mimicry	mimicry	NN
cord-009615-xcz8m9a7	24	7	hypothesis	hypothesis	NN
cord-009615-xcz8m9a7	24	8	of	of	IN
cord-009615-xcz8m9a7	24	9	viral	viral	JJ
cord-009615-xcz8m9a7	24	10	induction	induction	NN
cord-009615-xcz8m9a7	24	11	of	of	IN
cord-009615-xcz8m9a7	24	12	autoimmunity	autoimmunity	NN
cord-009615-xcz8m9a7	24	13	by	by	IN
cord-009615-xcz8m9a7	24	14	chance	chance	NN
cord-009615-xcz8m9a7	24	15	cross	cross	NN
cord-009615-xcz8m9a7	24	16	-	-	NN
cord-009615-xcz8m9a7	24	17	reactivity	reactivity	NN
cord-009615-xcz8m9a7	24	18	with	with	IN
cord-009615-xcz8m9a7	24	19	brain	brain	NN
cord-009615-xcz8m9a7	24	20	antigens	antigen	NNS
cord-009615-xcz8m9a7	24	21	(	(	-LRB-
cord-009615-xcz8m9a7	24	22	30	30	CD
cord-009615-xcz8m9a7	24	23	)	)	-RRB-
cord-009615-xcz8m9a7	24	24	has	have	VBZ
cord-009615-xcz8m9a7	24	25	led	lead	VBN
cord-009615-xcz8m9a7	24	26	to	to	IN
cord-009615-xcz8m9a7	24	27	the	the	DT
cord-009615-xcz8m9a7	24	28	"	"	``
cord-009615-xcz8m9a7	24	29	multiple	multiple	JJ
cord-009615-xcz8m9a7	24	30	virus	virus	NN
cord-009615-xcz8m9a7	24	31	hypothesis	hypothesis	NN
cord-009615-xcz8m9a7	24	32	"	"	''
cord-009615-xcz8m9a7	24	33	(	(	-LRB-
cord-009615-xcz8m9a7	24	34	31	31	CD
cord-009615-xcz8m9a7	24	35	)	)	-RRB-
cord-009615-xcz8m9a7	24	36	which	which	WDT
cord-009615-xcz8m9a7	24	37	further	further	RB
cord-009615-xcz8m9a7	24	38	weakens	weaken	VBZ
cord-009615-xcz8m9a7	24	39	the	the	DT
cord-009615-xcz8m9a7	24	40	case	case	NN
cord-009615-xcz8m9a7	24	41	for	for	IN
cord-009615-xcz8m9a7	24	42	a	a	DT
cord-009615-xcz8m9a7	24	43	single	single	JJ
cord-009615-xcz8m9a7	24	44	specific	specific	JJ
cord-009615-xcz8m9a7	24	45	etiologic	etiologic	JJ
cord-009615-xcz8m9a7	24	46	viral	viral	JJ
cord-009615-xcz8m9a7	24	47	agent	agent	NN
cord-009615-xcz8m9a7	24	48	in	in	IN
cord-009615-xcz8m9a7	24	49	the	the	DT
cord-009615-xcz8m9a7	24	50	brain	brain	NN
cord-009615-xcz8m9a7	24	51	.	.	.
cord-009615-xcz8m9a7	25	1	Under	under	IN
cord-009615-xcz8m9a7	25	2	these	these	DT
cord-009615-xcz8m9a7	25	3	circumstances	circumstance	NNS
cord-009615-xcz8m9a7	25	4	any	any	DT
cord-009615-xcz8m9a7	25	5	single	single	JJ
cord-009615-xcz8m9a7	25	6	-	-	HYPH
cord-009615-xcz8m9a7	25	7	virus	virus	NN
cord-009615-xcz8m9a7	25	8	etiology	etiology	NN
cord-009615-xcz8m9a7	25	9	proposed	propose	VBN
cord-009615-xcz8m9a7	25	10	for	for	IN
cord-009615-xcz8m9a7	25	11	MS	MS	NNP
cord-009615-xcz8m9a7	25	12	tends	tend	VBZ
cord-009615-xcz8m9a7	25	13	to	to	TO
cord-009615-xcz8m9a7	25	14	face	face	VB
cord-009615-xcz8m9a7	25	15	a	a	DT
cord-009615-xcz8m9a7	25	16	skeptical	skeptical	JJ
cord-009615-xcz8m9a7	25	17	reception	reception	NN
cord-009615-xcz8m9a7	25	18	.	.	.
cord-009615-xcz8m9a7	26	1	It	-PRON-	PRP
cord-009615-xcz8m9a7	26	2	is	be	VBZ
cord-009615-xcz8m9a7	26	3	not	not	RB
cord-009615-xcz8m9a7	26	4	the	the	DT
cord-009615-xcz8m9a7	26	5	purpose	purpose	NN
cord-009615-xcz8m9a7	26	6	of	of	IN
cord-009615-xcz8m9a7	26	7	this	this	DT
cord-009615-xcz8m9a7	26	8	presentation	presentation	NN
cord-009615-xcz8m9a7	26	9	to	to	TO
cord-009615-xcz8m9a7	26	10	review	review	VB
cord-009615-xcz8m9a7	26	11	the	the	DT
cord-009615-xcz8m9a7	26	12	entire	entire	JJ
cord-009615-xcz8m9a7	26	13	field	field	NN
cord-009615-xcz8m9a7	26	14	of	of	IN
cord-009615-xcz8m9a7	26	15	virus	virus	NN
cord-009615-xcz8m9a7	26	16	persistence	persistence	NN
cord-009615-xcz8m9a7	26	17	and	and	CC
cord-009615-xcz8m9a7	26	18	demyelination	demyelination	NN
cord-009615-xcz8m9a7	26	19	,	,	,
cord-009615-xcz8m9a7	26	20	nor	nor	CC
cord-009615-xcz8m9a7	26	21	to	to	TO
cord-009615-xcz8m9a7	26	22	make	make	VB
cord-009615-xcz8m9a7	26	23	a	a	DT
cord-009615-xcz8m9a7	26	24	case	case	NN
cord-009615-xcz8m9a7	26	25	for	for	IN
cord-009615-xcz8m9a7	26	26	a	a	DT
cord-009615-xcz8m9a7	26	27	particular	particular	JJ
cord-009615-xcz8m9a7	26	28	virus	virus	NN
cord-009615-xcz8m9a7	26	29	as	as	IN
cord-009615-xcz8m9a7	26	30	a	a	DT
cord-009615-xcz8m9a7	26	31	major	major	JJ
cord-009615-xcz8m9a7	26	32	cause	cause	NN
cord-009615-xcz8m9a7	26	33	of	of	IN
cord-009615-xcz8m9a7	26	34	MS	MS	NNP
cord-009615-xcz8m9a7	26	35	,	,	,
cord-009615-xcz8m9a7	26	36	but	but	CC
cord-009615-xcz8m9a7	26	37	rather	rather	RB
cord-009615-xcz8m9a7	26	38	to	to	TO
cord-009615-xcz8m9a7	26	39	use	use	VB
cord-009615-xcz8m9a7	26	40	the	the	DT
cord-009615-xcz8m9a7	26	41	example	example	NN
cord-009615-xcz8m9a7	26	42	of	of	IN
cord-009615-xcz8m9a7	26	43	a	a	DT
cord-009615-xcz8m9a7	26	44	ubiquitous	ubiquitous	JJ
cord-009615-xcz8m9a7	26	45	virus	virus	NN
cord-009615-xcz8m9a7	26	46	with	with	IN
cord-009615-xcz8m9a7	26	47	tropism	tropism	NN
cord-009615-xcz8m9a7	26	48	for	for	IN
cord-009615-xcz8m9a7	26	49	glial	glial	JJ
cord-009615-xcz8m9a7	26	50	cells	cell	NNS
cord-009615-xcz8m9a7	26	51	to	to	TO
cord-009615-xcz8m9a7	26	52	illustrate	illustrate	VB
cord-009615-xcz8m9a7	26	53	the	the	DT
cord-009615-xcz8m9a7	26	54	value	value	NN
cord-009615-xcz8m9a7	26	55	of	of	IN
cord-009615-xcz8m9a7	26	56	a	a	DT
cord-009615-xcz8m9a7	26	57	modified	modify	VBN
cord-009615-xcz8m9a7	26	58	paradigm	paradigm	NN
cord-009615-xcz8m9a7	26	59	for	for	IN
cord-009615-xcz8m9a7	26	60	investi-	investi-	NN
cord-009615-xcz8m9a7	26	61	would	would	MD
cord-009615-xcz8m9a7	26	62	be	be	VB
cord-009615-xcz8m9a7	26	63	the	the	DT
cord-009615-xcz8m9a7	26	64	closely	closely	RB
cord-009615-xcz8m9a7	26	65	related	related	JJ
cord-009615-xcz8m9a7	26	66	human	human	JJ
cord-009615-xcz8m9a7	26	67	polyomaviruses	polyomaviruse	NNS
cord-009615-xcz8m9a7	26	68	known	know	VBN
cord-009615-xcz8m9a7	26	69	as	as	IN
cord-009615-xcz8m9a7	26	70	JC	JC	NNP
cord-009615-xcz8m9a7	26	71	virus	virus	NN
cord-009615-xcz8m9a7	26	72	UCV	UCV	NNP
cord-009615-xcz8m9a7	26	73	)	)	-RRB-
cord-009615-xcz8m9a7	27	1	(	(	-LRB-
cord-009615-xcz8m9a7	27	2	46	46	CD
cord-009615-xcz8m9a7	27	3	)	)	-RRB-
cord-009615-xcz8m9a7	27	4	and	and	CC
cord-009615-xcz8m9a7	27	5	BK	BK	NNP
cord-009615-xcz8m9a7	27	6	virus	virus	NN
cord-009615-xcz8m9a7	27	7	(	(	-LRB-
cord-009615-xcz8m9a7	27	8	BKV	BKV	NNP
cord-009615-xcz8m9a7	27	9	)	)	-RRB-
cord-009615-xcz8m9a7	27	10	(	(	-LRB-
cord-009615-xcz8m9a7	27	11	47	47	CD
cord-009615-xcz8m9a7	27	12	)	)	-RRB-
cord-009615-xcz8m9a7	27	13	.	.	.
cord-009615-xcz8m9a7	28	1	Serological	serological	JJ
cord-009615-xcz8m9a7	28	2	evidence	evidence	NN
cord-009615-xcz8m9a7	28	3	suggests	suggest	VBZ
cord-009615-xcz8m9a7	28	4	that	that	IN
cord-009615-xcz8m9a7	28	5	JCV	JCV	NNP
cord-009615-xcz8m9a7	28	6	and	and	CC
cord-009615-xcz8m9a7	28	7	BKV	BKV	NNP
cord-009615-xcz8m9a7	28	8	each	each	DT
cord-009615-xcz8m9a7	28	9	The	the	DT
cord-009615-xcz8m9a7	28	10	Nature	Nature	NNP
cord-009615-xcz8m9a7	28	11	Of	of	IN
cord-009615-xcz8m9a7	28	12	a	a	DT
cord-009615-xcz8m9a7	28	13	Muitiipie	muitiipie	NN
cord-009615-xcz8m9a7	29	1	It	-PRON-	PRP
cord-009615-xcz8m9a7	29	2	is	be	VBZ
cord-009615-xcz8m9a7	29	3	thought	think	VBN
cord-009615-xcz8m9a7	29	4	that	that	IN
cord-009615-xcz8m9a7	29	5	an	an	DT
cord-009615-xcz8m9a7	29	6	MS	MS	NNP
cord-009615-xcz8m9a7	29	7	virus	virus	NN
cord-009615-xcz8m9a7	29	8	could	could	MD
cord-009615-xcz8m9a7	29	9	be	be	VB
cord-009615-xcz8m9a7	29	10	one	one	CD
cord-009615-xcz8m9a7	29	11	of	of	IN
cord-009615-xcz8m9a7	29	12	two	two	CD
cord-009615-xcz8m9a7	29	13	basic	basic	JJ
cord-009615-xcz8m9a7	29	14	types	type	NNS
cord-009615-xcz8m9a7	29	15	:	:	:
cord-009615-xcz8m9a7	29	16	1	1	LS
cord-009615-xcz8m9a7	29	17	)	)	-RRB-
cord-009615-xcz8m9a7	30	1	A	a	DT
cord-009615-xcz8m9a7	30	2	rare	rare	JJ
cord-009615-xcz8m9a7	30	3	agent	agent	NN
cord-009615-xcz8m9a7	30	4	which	which	WDT
cord-009615-xcz8m9a7	30	5	infects	infect	VBZ
cord-009615-xcz8m9a7	30	6	relatively	relatively	RB
cord-009615-xcz8m9a7	30	7	few	few	JJ
cord-009615-xcz8m9a7	30	8	individuals	individual	NNS
cord-009615-xcz8m9a7	30	9	but	but	CC
cord-009615-xcz8m9a7	30	10	is	be	VBZ
cord-009615-xcz8m9a7	30	11	frequently	frequently	RB
cord-009615-xcz8m9a7	30	12	pathogenic	pathogenic	JJ
cord-009615-xcz8m9a7	30	13	,	,	,
cord-009615-xcz8m9a7	30	14	or	or	CC
cord-009615-xcz8m9a7	30	15	2	2	CD
cord-009615-xcz8m9a7	30	16	)	)	-RRB-
cord-009615-xcz8m9a7	31	1	A	a	DT
cord-009615-xcz8m9a7	31	2	common	common	JJ
cord-009615-xcz8m9a7	31	3	agent	agent	NN
cord-009615-xcz8m9a7	31	4	which	which	WDT
cord-009615-xcz8m9a7	31	5	infects	infect	VBZ
cord-009615-xcz8m9a7	31	6	a	a	DT
cord-009615-xcz8m9a7	31	7	majority	majority	NN
cord-009615-xcz8m9a7	31	8	of	of	IN
cord-009615-xcz8m9a7	31	9	the	the	DT
cord-009615-xcz8m9a7	31	10	population	population	NN
cord-009615-xcz8m9a7	31	11	and	and	CC
cord-009615-xcz8m9a7	31	12	perhaps	perhaps	RB
cord-009615-xcz8m9a7	31	13	a	a	DT
cord-009615-xcz8m9a7	31	14	significant	significant	JJ
cord-009615-xcz8m9a7	31	15	number	number	NN
cord-009615-xcz8m9a7	31	16	of	of	IN
cord-009615-xcz8m9a7	31	17	normal	normal	JJ
cord-009615-xcz8m9a7	31	18	brains	brain	NNS
cord-009615-xcz8m9a7	31	19	,	,	,
cord-009615-xcz8m9a7	31	20	but	but	CC
cord-009615-xcz8m9a7	31	21	,	,	,
cord-009615-xcz8m9a7	31	22	in	in	IN
cord-009615-xcz8m9a7	31	23	which	which	WDT
cord-009615-xcz8m9a7	31	24	the	the	DT
cord-009615-xcz8m9a7	31	25	virus	virus	NN
cord-009615-xcz8m9a7	31	26	expression	expression	NN
cord-009615-xcz8m9a7	31	27	and	and	CC
cord-009615-xcz8m9a7	31	28	the	the	DT
cord-009615-xcz8m9a7	31	29	host	host	NN
cord-009615-xcz8m9a7	31	30	response	response	NN
cord-009615-xcz8m9a7	31	31	to	to	IN
cord-009615-xcz8m9a7	31	32	the	the	DT
cord-009615-xcz8m9a7	31	33	infection	infection	NN
cord-009615-xcz8m9a7	31	34	(	(	-LRB-
cord-009615-xcz8m9a7	31	35	Immunocytochemical	Immunocytochemical	NNP
cord-009615-xcz8m9a7	31	36	studies	study	NNS
cord-009615-xcz8m9a7	31	37	in	in	IN
cord-009615-xcz8m9a7	31	38	our	-PRON-	PRP$
cord-009615-xcz8m9a7	31	39	laboratory	laboratory	NN
cord-009615-xcz8m9a7	31	40	indicate	indicate	VBP
cord-009615-xcz8m9a7	31	41	that	that	IN
cord-009615-xcz8m9a7	31	42	perivascular	perivascular	JJ
cord-009615-xcz8m9a7	31	43	cellular	cellular	JJ
cord-009615-xcz8m9a7	31	44	infiltration	infiltration	NN
cord-009615-xcz8m9a7	31	45	,	,	,
cord-009615-xcz8m9a7	31	46	apparently	apparently	RB
cord-009615-xcz8m9a7	31	47	due	due	JJ
cord-009615-xcz8m9a7	31	48	to	to	IN
cord-009615-xcz8m9a7	31	49	immunological	immunological	JJ
cord-009615-xcz8m9a7	31	50	reactivity	reactivity	NN
cord-009615-xcz8m9a7	31	51	to	to	IN
cord-009615-xcz8m9a7	31	52	SV40	SV40	NNP
cord-009615-xcz8m9a7	31	53	antigens	antigen	NNS
cord-009615-xcz8m9a7	31	54	,	,	,
cord-009615-xcz8m9a7	31	55	occurs	occur	VBZ
cord-009615-xcz8m9a7	31	56	in	in	IN
cord-009615-xcz8m9a7	31	57	this	this	DT
cord-009615-xcz8m9a7	31	58	model	model	NN
cord-009615-xcz8m9a7	32	1	(	(	-LRB-
cord-009615-xcz8m9a7	32	2	Fig	Fig	NNP
cord-009615-xcz8m9a7	32	3	.	.	NNP
cord-009615-xcz8m9a7	32	4	1	1	CD
cord-009615-xcz8m9a7	32	5	)	)	-RRB-
cord-009615-xcz8m9a7	32	6	.	.	.
cord-009615-xcz8m9a7	33	1	These	these	DT
cord-009615-xcz8m9a7	33	2	results	result	NNS
cord-009615-xcz8m9a7	33	3	suggest	suggest	VBP
cord-009615-xcz8m9a7	33	4	that	that	IN
cord-009615-xcz8m9a7	33	5	SV40	SV40	NNP
cord-009615-xcz8m9a7	33	6	in	in	IN
cord-009615-xcz8m9a7	33	7	brain	brain	NN
cord-009615-xcz8m9a7	33	8	glial	glial	NN
cord-009615-xcz8m9a7	33	9	cells	cell	NNS
cord-009615-xcz8m9a7	33	10	around	around	IN
cord-009615-xcz8m9a7	33	11	vessels	vessel	NNS
cord-009615-xcz8m9a7	33	12	can	can	MD
cord-009615-xcz8m9a7	33	13	trigger	trigger	VB
cord-009615-xcz8m9a7	33	14	lymphocytic	lymphocytic	JJ
cord-009615-xcz8m9a7	33	15	infiltration	infiltration	NN
cord-009615-xcz8m9a7	33	16	.	.	.
cord-009615-xcz8m9a7	34	1	Although	although	IN
cord-009615-xcz8m9a7	34	2	human	human	JJ
cord-009615-xcz8m9a7	34	3	PML	PML	NNP
cord-009615-xcz8m9a7	34	4	is	be	VBZ
cord-009615-xcz8m9a7	34	5	thought	think	VBN
cord-009615-xcz8m9a7	34	6	to	to	TO
cord-009615-xcz8m9a7	34	7	characteristically	characteristically	RB
cord-009615-xcz8m9a7	34	8	lack	lack	VB
cord-009615-xcz8m9a7	34	9	perivascular	perivascular	JJ
cord-009615-xcz8m9a7	34	10	mononuclear	mononuclear	JJ
cord-009615-xcz8m9a7	34	11	cell	cell	NN
cord-009615-xcz8m9a7	34	12	infiltration	infiltration	NN
cord-009615-xcz8m9a7	34	13	because	because	IN
cord-009615-xcz8m9a7	34	14	of	of	IN
cord-009615-xcz8m9a7	34	15	the	the	DT
cord-009615-xcz8m9a7	34	16	underlying	underlie	VBG
cord-009615-xcz8m9a7	34	17	immunocompromising	immunocompromising	NN
cord-009615-xcz8m9a7	34	18	condition	condition	NN
cord-009615-xcz8m9a7	34	19	,	,	,
cord-009615-xcz8m9a7	34	20	in	in	IN
cord-009615-xcz8m9a7	34	21	fact	fact	NN
cord-009615-xcz8m9a7	34	22	perivascular	perivascular	JJ
cord-009615-xcz8m9a7	34	23	cuffing	cuffing	NN
cord-009615-xcz8m9a7	34	24	does	do	VBZ
cord-009615-xcz8m9a7	34	25	occur	occur	VB
cord-009615-xcz8m9a7	35	1	(	(	-LRB-
cord-009615-xcz8m9a7	35	2	e.g.	e.g.	RB
cord-009615-xcz8m9a7	35	3	,	,	,
cord-009615-xcz8m9a7	35	4	see	see	VB
cord-009615-xcz8m9a7	35	5	description	description	NN
cord-009615-xcz8m9a7	35	6	of	of	IN
cord-009615-xcz8m9a7	35	7	cases	case	NNS
cord-009615-xcz8m9a7	35	8	4	4	CD
cord-009615-xcz8m9a7	35	9	,	,	,
cord-009615-xcz8m9a7	35	10	6	6	CD
cord-009615-xcz8m9a7	35	11	and	and	CC
cord-009615-xcz8m9a7	35	12	7	7	CD
cord-009615-xcz8m9a7	35	13	of	of	IN
cord-009615-xcz8m9a7	35	14	Richardson	Richardson	NNP
cord-009615-xcz8m9a7	35	15	(	(	-LRB-
cord-009615-xcz8m9a7	35	16	81	81	CD
cord-009615-xcz8m9a7	35	17	)	)	-RRB-
cord-009615-xcz8m9a7	35	18	)	)	-RRB-
cord-009615-xcz8m9a7	35	19	and	and	CC
cord-009615-xcz8m9a7	35	20	the	the	DT
cord-009615-xcz8m9a7	35	21	simian	simian	JJ
cord-009615-xcz8m9a7	35	22	model	model	NN
cord-009615-xcz8m9a7	35	23	may	may	MD
cord-009615-xcz8m9a7	35	24	not	not	RB
cord-009615-xcz8m9a7	35	25	be	be	VB
cord-009615-xcz8m9a7	35	26	different	different	JJ
cord-009615-xcz8m9a7	35	27	in	in	IN
cord-009615-xcz8m9a7	35	28	this	this	DT
cord-009615-xcz8m9a7	35	29	regard	regard	NN
cord-009615-xcz8m9a7	35	30	.	.	.
cord-009615-xcz8m9a7	36	1	While	while	IN
cord-009615-xcz8m9a7	36	2	its	-PRON-	PRP$
cord-009615-xcz8m9a7	36	3	relevance	relevance	NN
cord-009615-xcz8m9a7	36	4	as	as	IN
cord-009615-xcz8m9a7	36	5	a	a	DT
cord-009615-xcz8m9a7	36	6	PML	PML	NNP
cord-009615-xcz8m9a7	36	7	model	model	NN
cord-009615-xcz8m9a7	36	8	is	be	VBZ
cord-009615-xcz8m9a7	36	9	apparent	apparent	JJ
cord-009615-xcz8m9a7	36	10	,	,	,
cord-009615-xcz8m9a7	36	11	the	the	DT
cord-009615-xcz8m9a7	36	12	SV40-infected	sv40-infected	JJ
cord-009615-xcz8m9a7	36	13	macaque	macaque	NN
cord-009615-xcz8m9a7	36	14	might	may	MD
cord-009615-xcz8m9a7	36	15	also	also	RB
cord-009615-xcz8m9a7	36	16	provide	provide	VB
cord-009615-xcz8m9a7	36	17	a	a	DT
cord-009615-xcz8m9a7	36	18	model	model	NN
cord-009615-xcz8m9a7	36	19	for	for	IN
cord-009615-xcz8m9a7	36	20	MS	MS	NNP
cord-009615-xcz8m9a7	36	21	-	-	HYPH
cord-009615-xcz8m9a7	36	22	like	like	JJ
cord-009615-xcz8m9a7	36	23	disease	disease	NN
cord-009615-xcz8m9a7	36	24	induced	induce	VBN
cord-009615-xcz8m9a7	36	25	by	by	IN
cord-009615-xcz8m9a7	36	26	a	a	DT
cord-009615-xcz8m9a7	36	27	latent	latent	JJ
cord-009615-xcz8m9a7	36	28	virus	virus	NN
cord-009615-xcz8m9a7	36	29	.	.	.
cord-009615-xcz8m9a7	37	1	If	if	IN
cord-009615-xcz8m9a7	37	2	some	some	DT
cord-009615-xcz8m9a7	37	3	of	of	IN
cord-009615-xcz8m9a7	37	4	these	these	DT
cord-009615-xcz8m9a7	37	5	animals	animal	NNS
cord-009615-xcz8m9a7	37	6	carry	carry	VBP
cord-009615-xcz8m9a7	37	7	a	a	DT
cord-009615-xcz8m9a7	37	8	latent	latent	JJ
cord-009615-xcz8m9a7	37	9	SV40	SV40	NNP
cord-009615-xcz8m9a7	37	10	infection	infection	NN
cord-009615-xcz8m9a7	37	11	in	in	IN
cord-009615-xcz8m9a7	37	12	the	the	DT
cord-009615-xcz8m9a7	37	13	brain	brain	NN
cord-009615-xcz8m9a7	37	14	,	,	,
cord-009615-xcz8m9a7	37	15	and	and	CC
cord-009615-xcz8m9a7	37	16	the	the	DT
cord-009615-xcz8m9a7	37	17	balance	balance	NN
cord-009615-xcz8m9a7	37	18	between	between	IN
cord-009615-xcz8m9a7	37	19	viral	viral	JJ
cord-009615-xcz8m9a7	37	20	expression	expression	NN
cord-009615-xcz8m9a7	37	21	and	and	CC
cord-009615-xcz8m9a7	37	22	anti	anti	JJ
cord-009615-xcz8m9a7	37	23	-	-	JJ
cord-009615-xcz8m9a7	37	24	SV40	sv40	JJ
cord-009615-xcz8m9a7	37	25	immunity	immunity	NN
cord-009615-xcz8m9a7	37	26	tips	tip	NNS
cord-009615-xcz8m9a7	37	27	to	to	IN
cord-009615-xcz8m9a7	37	28	the	the	DT
cord-009615-xcz8m9a7	37	29	other	other	JJ
cord-009615-xcz8m9a7	37	30	side	side	NN
cord-009615-xcz8m9a7	37	31	so	so	IN
cord-009615-xcz8m9a7	37	32	that	that	IN
cord-009615-xcz8m9a7	37	33	SV40	SV40	NNP
cord-009615-xcz8m9a7	37	34	reactivation	reactivation	NN
cord-009615-xcz8m9a7	37	35	is	be	VBZ
cord-009615-xcz8m9a7	37	36	abortive	abortive	JJ
cord-009615-xcz8m9a7	37	37	,	,	,
cord-009615-xcz8m9a7	37	38	then	then	RB
cord-009615-xcz8m9a7	37	39	the	the	DT
cord-009615-xcz8m9a7	37	40	pathology	pathology	NN
cord-009615-xcz8m9a7	37	41	might	may	MD
cord-009615-xcz8m9a7	37	42	be	be	VB
cord-009615-xcz8m9a7	37	43	limited	limit	VBN
cord-009615-xcz8m9a7	37	44	to	to	IN
cord-009615-xcz8m9a7	37	45	immune	immune	JJ
cord-009615-xcz8m9a7	37	46	-	-	HYPH
cord-009615-xcz8m9a7	37	47	mediated	mediate	VBN
cord-009615-xcz8m9a7	37	48	destruction	destruction	NN
cord-009615-xcz8m9a7	37	49	of	of	IN
cord-009615-xcz8m9a7	37	50	glial	glial	JJ
cord-009615-xcz8m9a7	37	51	cells	cell	NNS
cord-009615-xcz8m9a7	37	52	with	with	IN
cord-009615-xcz8m9a7	37	53	primary	primary	JJ
cord-009615-xcz8m9a7	37	54	demyelination	demyelination	NN
cord-009615-xcz8m9a7	37	55	.	.	.
cord-009615-xcz8m9a7	38	1	Thus	thus	RB
cord-009615-xcz8m9a7	38	2	,	,	,
cord-009615-xcz8m9a7	38	3	simian	simian	JJ
cord-009615-xcz8m9a7	38	4	immunodeficiency	immunodeficiency	NN
cord-009615-xcz8m9a7	38	5	virus	virus	NN
cord-009615-xcz8m9a7	38	6	(	(	-LRB-
cord-009615-xcz8m9a7	38	7	S1V)-infected	s1v)-infected	CD
cord-009615-xcz8m9a7	38	8	macaques	macaque	NNS
cord-009615-xcz8m9a7	38	9	should	should	MD
cord-009615-xcz8m9a7	38	10	be	be	VB
cord-009615-xcz8m9a7	38	11	observed	observe	VBN
cord-009615-xcz8m9a7	38	12	regularly	regularly	RB
cord-009615-xcz8m9a7	38	13	for	for	IN
cord-009615-xcz8m9a7	38	14	the	the	DT
cord-009615-xcz8m9a7	38	15	possible	possible	JJ
cord-009615-xcz8m9a7	38	16	occurrence	occurrence	NN
cord-009615-xcz8m9a7	38	17	of	of	IN
cord-009615-xcz8m9a7	38	18	MS	MS	NNP
cord-009615-xcz8m9a7	38	19	-	-	HYPH
cord-009615-xcz8m9a7	38	20	like	like	JJ
cord-009615-xcz8m9a7	38	21	signs	sign	NNS
cord-009615-xcz8m9a7	38	22	with	with	IN
cord-009615-xcz8m9a7	38	23	demyelination	demyelination	NN
cord-009615-xcz8m9a7	38	24	attributable	attributable	JJ
cord-009615-xcz8m9a7	38	25	to	to	IN
cord-009615-xcz8m9a7	38	26	mononuclear	mononuclear	JJ
cord-009615-xcz8m9a7	38	27	cell	cell	NN
cord-009615-xcz8m9a7	38	28	infiltration	infiltration	NN
cord-009615-xcz8m9a7	38	29	in	in	IN
cord-009615-xcz8m9a7	38	30	response	response	NN
cord-009615-xcz8m9a7	38	31	to	to	IN
cord-009615-xcz8m9a7	38	32	abortively	abortively	RB
cord-009615-xcz8m9a7	38	33	infected	infected	JJ
cord-009615-xcz8m9a7	38	34	glial	glial	JJ
cord-009615-xcz8m9a7	38	35	cells	cell	NNS
cord-009615-xcz8m9a7	38	36	,	,	,
cord-009615-xcz8m9a7	38	37	rather	rather	RB
cord-009615-xcz8m9a7	38	38	twa	twa	JJ
cord-009615-xcz8m9a7	38	39	-	-	HYPH
cord-009615-xcz8m9a7	38	40	stage	stage	NN
cord-009615-xcz8m9a7	38	41	process	process	NN
cord-009615-xcz8m9a7	38	42	of	of	IN
cord-009615-xcz8m9a7	38	43	deletion	deletion	NN
cord-009615-xcz8m9a7	38	44	and	and	CC
cord-009615-xcz8m9a7	38	45	duplication	duplication	NN
cord-009615-xcz8m9a7	38	46	known	know	VBN
cord-009615-xcz8m9a7	38	47	as	as	IN
cord-009615-xcz8m9a7	38	48	"	"	``
cord-009615-xcz8m9a7	38	49	brain	brain	NN
cord-009615-xcz8m9a7	38	50	adaptation	adaptation	NN
cord-009615-xcz8m9a7	38	51	"	"	''
cord-009615-xcz8m9a7	38	52	to	to	TO
cord-009615-xcz8m9a7	38	53	generate	generate	VB
cord-009615-xcz8m9a7	38	54	the	the	DT
cord-009615-xcz8m9a7	38	55	progressive	progressive	JJ
cord-009615-xcz8m9a7	38	56	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	38	57	leukoencephalopathy	leukoencephalopathy	NNS
cord-009615-xcz8m9a7	38	58	(	(	-LRB-
cord-009615-xcz8m9a7	38	59	PML)-type	pml)-type	CD
cord-009615-xcz8m9a7	38	60	viral	viral	JJ
cord-009615-xcz8m9a7	38	61	genome	genome	NN
cord-009615-xcz8m9a7	38	62	capable	capable	JJ
cord-009615-xcz8m9a7	38	63	of	of	IN
cord-009615-xcz8m9a7	38	64	replicating	replicate	VBG
cord-009615-xcz8m9a7	38	65	in	in	IN
cord-009615-xcz8m9a7	38	66	glial	glial	JJ
cord-009615-xcz8m9a7	38	67	cells	cell	NNS
cord-009615-xcz8m9a7	38	68	of	of	IN
cord-009615-xcz8m9a7	38	69	the	the	DT
cord-009615-xcz8m9a7	38	70	human	human	JJ
cord-009615-xcz8m9a7	38	71	brain	brain	NN
cord-009615-xcz8m9a7	38	72	.	.	.
cord-009615-xcz8m9a7	39	1	It	-PRON-	PRP
cord-009615-xcz8m9a7	39	2	is	be	VBZ
cord-009615-xcz8m9a7	39	3	this	this	DT
cord-009615-xcz8m9a7	39	4	rearranged	rearrange	VBN
cord-009615-xcz8m9a7	39	5	promoter/	promoter/	NN
cord-009615-xcz8m9a7	39	6	enhancer	enhancer	NN
cord-009615-xcz8m9a7	39	7	,	,	,
cord-009615-xcz8m9a7	39	8	not	not	RB
cord-009615-xcz8m9a7	39	9	the	the	DT
cord-009615-xcz8m9a7	39	10	archetypal	archetypal	JJ
cord-009615-xcz8m9a7	39	11	form	form	NN
cord-009615-xcz8m9a7	39	12	circulating	circulate	VBG
cord-009615-xcz8m9a7	39	13	in	in	IN
cord-009615-xcz8m9a7	39	14	the	the	DT
cord-009615-xcz8m9a7	39	15	population	population	NN
cord-009615-xcz8m9a7	39	16	,	,	,
cord-009615-xcz8m9a7	39	17	which	which	WDT
cord-009615-xcz8m9a7	39	18	becomes	become	VBZ
cord-009615-xcz8m9a7	39	19	neurotropic	neurotropic	NNP
cord-009615-xcz8m9a7	39	20	in	in	IN
cord-009615-xcz8m9a7	39	21	its	-PRON-	PRP$
cord-009615-xcz8m9a7	39	22	host	host	NN
cord-009615-xcz8m9a7	39	23	.	.	.
cord-009615-xcz8m9a7	40	1	The	the	DT
cord-009615-xcz8m9a7	40	2	JCV	JCV	NNP
cord-009615-xcz8m9a7	40	3	isolates	isolate	VBZ
cord-009615-xcz8m9a7	40	4	obtained	obtain	VBN
cord-009615-xcz8m9a7	40	5	from	from	IN
cord-009615-xcz8m9a7	40	6	11	11	CD
cord-009615-xcz8m9a7	40	7	PML	PML	NNP
cord-009615-xcz8m9a7	40	8	brains	brain	NNS
cord-009615-xcz8m9a7	40	9	-	-	,
cord-009615-xcz8m9a7	40	10	were	be	VBD
cord-009615-xcz8m9a7	40	11	each	each	DT
cord-009615-xcz8m9a7	40	12	uniquely	uniquely	RB
cord-009615-xcz8m9a7	40	13	rearranged	rearrange	VBN
cord-009615-xcz8m9a7	40	14	;	;	:
cord-009615-xcz8m9a7	40	15	none	none	NN
cord-009615-xcz8m9a7	40	16	was	be	VBD
cord-009615-xcz8m9a7	40	17	identical	identical	JJ
cord-009615-xcz8m9a7	40	18	to	to	IN
cord-009615-xcz8m9a7	40	19	the	the	DT
cord-009615-xcz8m9a7	40	20	prototype	prototype	NN
cord-009615-xcz8m9a7	40	21	Mad-1	Mad-1	NNP
cord-009615-xcz8m9a7	40	22	strain	strain	VB
cord-009615-xcz8m9a7	40	23	.	.	.
cord-009615-xcz8m9a7	41	1	The	the	DT
cord-009615-xcz8m9a7	41	2	host	host	NN
cord-009615-xcz8m9a7	41	3	enzymes	enzymes	VBP
cord-009615-xcz8m9a7	41	4	mediating	mediate	VBG
cord-009615-xcz8m9a7	41	5	these	these	DT
cord-009615-xcz8m9a7	41	6	rearrangements	rearrangement	NNS
cord-009615-xcz8m9a7	41	7	are	be	VBP
cord-009615-xcz8m9a7	41	8	unknown	unknown	JJ
cord-009615-xcz8m9a7	41	9	.	.	.
cord-009615-xcz8m9a7	42	1	Diagram	Diagram	NNP
cord-009615-xcz8m9a7	42	2	modified	modify	VBN
cord-009615-xcz8m9a7	42	3	from	from	IN
cord-009615-xcz8m9a7	42	4	J	J	NNP
cord-009615-xcz8m9a7	42	5	vim/	vim/	NNP
cord-009615-xcz8m9a7	42	6	64	64	CD
cord-009615-xcz8m9a7	42	7	:	:	:
cord-009615-xcz8m9a7	42	8	31	31	CD
cord-009615-xcz8m9a7	42	9	39	39	CD
cord-009615-xcz8m9a7	42	10	-	-	SYM
cord-009615-xcz8m9a7	42	11	31	31	CD
cord-009615-xcz8m9a7	42	12	43	43	CD
cord-009615-xcz8m9a7	42	13	,	,	,
cord-009615-xcz8m9a7	42	14	reference	reference	NN
cord-009615-xcz8m9a7	42	15	83	83	CD
cord-009615-xcz8m9a7	42	16	.	.	.
cord-009615-xcz8m9a7	43	1	than	than	IN
cord-009615-xcz8m9a7	43	2	to	to	IN
cord-009615-xcz8m9a7	43	3	productive	productive	JJ
cord-009615-xcz8m9a7	43	4	SV40	SV40	NNP
cord-009615-xcz8m9a7	43	5	infection	infection	NN
cord-009615-xcz8m9a7	43	6	or	or	CC
cord-009615-xcz8m9a7	43	7	to	to	IN
cord-009615-xcz8m9a7	43	8	SIV	SIV	NNP
cord-009615-xcz8m9a7	43	9	-	-	HYPH
cord-009615-xcz8m9a7	43	10	induced	induce	VBN
cord-009615-xcz8m9a7	43	11	pathology	pathology	NN
cord-009615-xcz8m9a7	43	12	.	.	.
cord-009615-xcz8m9a7	44	1	Our	-PRON-	PRP$
cord-009615-xcz8m9a7	44	2	studies	study	NNS
cord-009615-xcz8m9a7	44	3	with	with	IN
cord-009615-xcz8m9a7	44	4	the	the	DT
cord-009615-xcz8m9a7	44	5	polymerase	polymerase	NN
cord-009615-xcz8m9a7	44	6	chain	chain	NN
cord-009615-xcz8m9a7	44	7	reaction	reaction	NN
cord-009615-xcz8m9a7	44	8	(	(	-LRB-
cord-009615-xcz8m9a7	44	9	PCR	PCR	NNP
cord-009615-xcz8m9a7	44	10	)	)	-RRB-
cord-009615-xcz8m9a7	44	11	on	on	IN
cord-009615-xcz8m9a7	44	12	frozen	frozen	JJ
cord-009615-xcz8m9a7	44	13	sections	section	NNS
cord-009615-xcz8m9a7	44	14	of	of	IN
cord-009615-xcz8m9a7	44	15	brain	brain	NN
cord-009615-xcz8m9a7	44	16	tissue	tissue	NN
cord-009615-xcz8m9a7	44	17	without	without	IN
cord-009615-xcz8m9a7	44	18	known	know	VBN
cord-009615-xcz8m9a7	44	19	neurological	neurological	JJ
cord-009615-xcz8m9a7	44	20	disease	disease	NN
cord-009615-xcz8m9a7	44	21	have	have	VBP
cord-009615-xcz8m9a7	44	22	shown	show	VBN
cord-009615-xcz8m9a7	44	23	that	that	IN
cord-009615-xcz8m9a7	44	24	as	as	RB
cord-009615-xcz8m9a7	44	25	many	many	JJ
cord-009615-xcz8m9a7	44	26	as	as	IN
cord-009615-xcz8m9a7	44	27	half	half	NN
cord-009615-xcz8m9a7	44	28	of	of	IN
cord-009615-xcz8m9a7	44	29	the	the	DT
cord-009615-xcz8m9a7	44	30	brains	brain	NNS
cord-009615-xcz8m9a7	44	31	may	may	MD
cord-009615-xcz8m9a7	44	32	contain	contain	VB
cord-009615-xcz8m9a7	44	33	very	very	RB
cord-009615-xcz8m9a7	44	34	low	low	JJ
cord-009615-xcz8m9a7	44	35	levels	level	NNS
cord-009615-xcz8m9a7	44	36	of	of	IN
cord-009615-xcz8m9a7	44	37	JCV	JCV	NNP
cord-009615-xcz8m9a7	44	38	DNA	DNA	NNP
cord-009615-xcz8m9a7	44	39	(	(	-LRB-
cord-009615-xcz8m9a7	44	40	54	54	CD
cord-009615-xcz8m9a7	44	41	)	)	-RRB-
cord-009615-xcz8m9a7	44	42	.	.	.
cord-009615-xcz8m9a7	45	1	Sequences	sequence	NNS
cord-009615-xcz8m9a7	45	2	of	of	IN
cord-009615-xcz8m9a7	45	3	amplified	amplify	VBN
cord-009615-xcz8m9a7	45	4	DNA	dna	NN
cord-009615-xcz8m9a7	45	5	fragments	fragment	NNS
cord-009615-xcz8m9a7	45	6	from	from	IN
cord-009615-xcz8m9a7	45	7	these	these	DT
cord-009615-xcz8m9a7	45	8	brains	brain	NNS
cord-009615-xcz8m9a7	45	9	have	have	VBP
cord-009615-xcz8m9a7	45	10	a	a	DT
cord-009615-xcz8m9a7	45	11	rearranged	rearrange	VBN
cord-009615-xcz8m9a7	45	12	regulatory	regulatory	JJ
cord-009615-xcz8m9a7	45	13	region	region	NN
cord-009615-xcz8m9a7	45	14	showing	show	VBG
cord-009615-xcz8m9a7	45	15	deletion	deletion	NN
cord-009615-xcz8m9a7	45	16	followed	follow	VBN
cord-009615-xcz8m9a7	45	17	by	by	IN
cord-009615-xcz8m9a7	45	18	duplication	duplication	NN
cord-009615-xcz8m9a7	45	19	of	of	IN
cord-009615-xcz8m9a7	45	20	promoter	promoter	NN
cord-009615-xcz8m9a7	45	21	/	/	SYM
cord-009615-xcz8m9a7	45	22	enhancer	enhancer	NN
cord-009615-xcz8m9a7	45	23	elements	element	NNS
cord-009615-xcz8m9a7	45	24	(	(	-LRB-
cord-009615-xcz8m9a7	45	25	54	54	CD
cord-009615-xcz8m9a7	45	26	)	)	-RRB-
cord-009615-xcz8m9a7	45	27	,	,	,
cord-009615-xcz8m9a7	45	28	rather	rather	RB
cord-009615-xcz8m9a7	45	29	than	than	IN
cord-009615-xcz8m9a7	45	30	the	the	DT
cord-009615-xcz8m9a7	45	31	stable	stable	JJ
cord-009615-xcz8m9a7	45	32	"	"	``
cord-009615-xcz8m9a7	45	33	archetypal	archetypal	JJ
cord-009615-xcz8m9a7	45	34	"	"	''
cord-009615-xcz8m9a7	45	35	form	form	NN
cord-009615-xcz8m9a7	45	36	which	which	WDT
cord-009615-xcz8m9a7	45	37	is	be	VBZ
cord-009615-xcz8m9a7	45	38	found	find	VBN
cord-009615-xcz8m9a7	45	39	in	in	IN
cord-009615-xcz8m9a7	45	40	the	the	DT
cord-009615-xcz8m9a7	45	41	kidney	kidney	NN
cord-009615-xcz8m9a7	45	42	and	and	CC
cord-009615-xcz8m9a7	45	43	shed	shed	VBD
cord-009615-xcz8m9a7	45	44	into	into	IN
cord-009615-xcz8m9a7	45	45	the	the	DT
cord-009615-xcz8m9a7	45	46	urine	urine	NN
cord-009615-xcz8m9a7	45	47	(	(	-LRB-
cord-009615-xcz8m9a7	45	48	82,83	82,83	CD
cord-009615-xcz8m9a7	45	49	)	)	-RRB-
cord-009615-xcz8m9a7	46	1	(	(	-LRB-
cord-009615-xcz8m9a7	46	2	Fig	Fig	NNP
cord-009615-xcz8m9a7	46	3	.	.	NNP
cord-009615-xcz8m9a7	46	4	2	2	CD
cord-009615-xcz8m9a7	46	5	)	)	-RRB-
cord-009615-xcz8m9a7	46	6	.	.	.
cord-009615-xcz8m9a7	47	1	There	there	EX
cord-009615-xcz8m9a7	47	2	is	be	VBZ
cord-009615-xcz8m9a7	47	3	additional	additional	JJ
cord-009615-xcz8m9a7	47	4	data	datum	NNS
cord-009615-xcz8m9a7	47	5	in	in	IN
cord-009615-xcz8m9a7	47	6	support	support	NN
cord-009615-xcz8m9a7	47	7	of	of	IN
cord-009615-xcz8m9a7	47	8	these	these	DT
cord-009615-xcz8m9a7	47	9	findings	finding	NNS
cord-009615-xcz8m9a7	47	10	.	.	.
cord-009615-xcz8m9a7	48	1	PCR	PCR	NNP
cord-009615-xcz8m9a7	48	2	analysis	analysis	NN
cord-009615-xcz8m9a7	48	3	of	of	IN
cord-009615-xcz8m9a7	48	4	DNA	DNA	NNP
cord-009615-xcz8m9a7	48	5	extracted	extract	VBN
cord-009615-xcz8m9a7	48	6	from	from	IN
cord-009615-xcz8m9a7	48	7	fixed	fix	VBN
cord-009615-xcz8m9a7	48	8	brain	brain	NN
cord-009615-xcz8m9a7	48	9	tissue	tissue	NN
cord-009615-xcz8m9a7	48	10	,	,	,
cord-009615-xcz8m9a7	48	11	obtained	obtain	VBN
cord-009615-xcz8m9a7	48	12	from	from	IN
cord-009615-xcz8m9a7	48	13	aged	aged	JJ
cord-009615-xcz8m9a7	48	14	individuals	individual	NNS
cord-009615-xcz8m9a7	48	15	without	without	IN
cord-009615-xcz8m9a7	48	16	PML	PML	NNP
cord-009615-xcz8m9a7	48	17	,	,	,
cord-009615-xcz8m9a7	48	18	was	be	VBD
cord-009615-xcz8m9a7	48	19	able	able	JJ
cord-009615-xcz8m9a7	48	20	to	to	TO
cord-009615-xcz8m9a7	48	21	detect	detect	VB
cord-009615-xcz8m9a7	48	22	JCV	JCV	NNP
cord-009615-xcz8m9a7	48	23	DNA	DNA	NNP
cord-009615-xcz8m9a7	48	24	in	in	IN
cord-009615-xcz8m9a7	48	25	one	one	CD
cord-009615-xcz8m9a7	48	26	-	-	HYPH
cord-009615-xcz8m9a7	48	27	third	third	NN
cord-009615-xcz8m9a7	48	28	of	of	IN
cord-009615-xcz8m9a7	48	29	the	the	DT
cord-009615-xcz8m9a7	48	30	brains	brain	NNS
cord-009615-xcz8m9a7	48	31	(	(	-LRB-
cord-009615-xcz8m9a7	48	32	55	55	CD
cord-009615-xcz8m9a7	48	33	)	)	-RRB-
cord-009615-xcz8m9a7	48	34	.	.	.
cord-009615-xcz8m9a7	49	1	In	in	IN
cord-009615-xcz8m9a7	49	2	another	another	DT
cord-009615-xcz8m9a7	49	3	study	study	NN
cord-009615-xcz8m9a7	49	4	in	in	IN
cord-009615-xcz8m9a7	49	5	which	which	WDT
cord-009615-xcz8m9a7	49	6	PCR	PCR	NNP
cord-009615-xcz8m9a7	49	7	was	be	VBD
cord-009615-xcz8m9a7	49	8	used	use	VBN
cord-009615-xcz8m9a7	49	9	to	to	TO
cord-009615-xcz8m9a7	49	10	detect	detect	VB
cord-009615-xcz8m9a7	49	11	JCV	JCV	NNP
cord-009615-xcz8m9a7	49	12	in	in	IN
cord-009615-xcz8m9a7	49	13	the	the	DT
cord-009615-xcz8m9a7	49	14	brains	brain	NNS
cord-009615-xcz8m9a7	49	15	of	of	IN
cord-009615-xcz8m9a7	49	16	human	human	JJ
cord-009615-xcz8m9a7	49	17	immunodeficiency	immunodeficiency	NN
cord-009615-xcz8m9a7	49	18	virus	virus	NN
cord-009615-xcz8m9a7	49	19	(	(	-LRB-
cord-009615-xcz8m9a7	49	20	H1V)-positive	h1v)-positive	CD
cord-009615-xcz8m9a7	49	21	individuals	individual	NNS
cord-009615-xcz8m9a7	49	22	without	without	IN
cord-009615-xcz8m9a7	49	23	AIDS	AIDS	NNP
cord-009615-xcz8m9a7	49	24	or	or	CC
cord-009615-xcz8m9a7	49	25	other	other	JJ
cord-009615-xcz8m9a7	49	26	CNS	CNS	NNP
cord-009615-xcz8m9a7	49	27	diseases	disease	NNS
cord-009615-xcz8m9a7	49	28	such	such	JJ
cord-009615-xcz8m9a7	49	29	as	as	IN
cord-009615-xcz8m9a7	49	30	PML	PML	NNP
cord-009615-xcz8m9a7	49	31	,	,	,
cord-009615-xcz8m9a7	49	32	4	4	CD
cord-009615-xcz8m9a7	49	33	of	of	IN
cord-009615-xcz8m9a7	49	34	13	13	CD
cord-009615-xcz8m9a7	49	35	brains	brain	NNS
cord-009615-xcz8m9a7	49	36	were	be	VBD
cord-009615-xcz8m9a7	49	37	found	find	VBN
cord-009615-xcz8m9a7	49	38	to	to	TO
cord-009615-xcz8m9a7	49	39	contain	contain	VB
cord-009615-xcz8m9a7	49	40	JCV	JCV	NNP
cord-009615-xcz8m9a7	49	41	DNA	DNA	NNP
cord-009615-xcz8m9a7	49	42	(	(	-LRB-
cord-009615-xcz8m9a7	49	43	56	56	CD
cord-009615-xcz8m9a7	49	44	)	)	-RRB-
cord-009615-xcz8m9a7	49	45	.	.	.
cord-009615-xcz8m9a7	50	1	In	in	IN
cord-009615-xcz8m9a7	50	2	that	that	DT
cord-009615-xcz8m9a7	50	3	same	same	JJ
cord-009615-xcz8m9a7	50	4	study	study	NN
cord-009615-xcz8m9a7	50	5	,	,	,
cord-009615-xcz8m9a7	50	6	JCV	JCV	NNP
cord-009615-xcz8m9a7	50	7	DNA	DNA	NNP
cord-009615-xcz8m9a7	50	8	was	be	VBD
cord-009615-xcz8m9a7	50	9	found	find	VBN
cord-009615-xcz8m9a7	50	10	in	in	IN
cord-009615-xcz8m9a7	50	11	1	1	CD
cord-009615-xcz8m9a7	50	12	of	of	IN
cord-009615-xcz8m9a7	50	13	the	the	DT
cord-009615-xcz8m9a7	50	14	12	12	CD
cord-009615-xcz8m9a7	50	15	normal	normal	JJ
cord-009615-xcz8m9a7	50	16	brains	brain	NNS
cord-009615-xcz8m9a7	50	17	.	.	.
cord-009615-xcz8m9a7	51	1	In	in	IN
cord-009615-xcz8m9a7	51	2	a	a	DT
cord-009615-xcz8m9a7	51	3	third	third	JJ
cord-009615-xcz8m9a7	51	4	study	study	NN
cord-009615-xcz8m9a7	51	5	,	,	,
cord-009615-xcz8m9a7	51	6	19	19	CD
cord-009615-xcz8m9a7	51	7	of	of	IN
cord-009615-xcz8m9a7	51	8	67	67	CD
cord-009615-xcz8m9a7	51	9	brains	brain	NNS
cord-009615-xcz8m9a7	51	10	without	without	IN
cord-009615-xcz8m9a7	51	11	PML	PML	NNP
cord-009615-xcz8m9a7	51	12	(	(	-LRB-
cord-009615-xcz8m9a7	51	13	28	28	CD
cord-009615-xcz8m9a7	51	14	%	%	NN
cord-009615-xcz8m9a7	51	15	)	)	-RRB-
cord-009615-xcz8m9a7	51	16	were	be	VBD
cord-009615-xcz8m9a7	51	17	found	find	VBN
cord-009615-xcz8m9a7	51	18	to	to	TO
cord-009615-xcz8m9a7	51	19	harbor	harbor	VB
cord-009615-xcz8m9a7	51	20	JCV	JCV	NNP
cord-009615-xcz8m9a7	51	21	DNA	DNA	NNP
cord-009615-xcz8m9a7	51	22	by	by	IN
cord-009615-xcz8m9a7	51	23	both	both	CC
cord-009615-xcz8m9a7	51	24	PCR	PCR	NNP
cord-009615-xcz8m9a7	51	25	and	and	CC
cord-009615-xcz8m9a7	51	26	Southern	southern	JJ
cord-009615-xcz8m9a7	51	27	blot	blot	NN
cord-009615-xcz8m9a7	51	28	hybridization	hybridization	NN
cord-009615-xcz8m9a7	51	29	analysis	analysis	NN
cord-009615-xcz8m9a7	51	30	(	(	-LRB-
cord-009615-xcz8m9a7	51	31	57	57	CD
cord-009615-xcz8m9a7	51	32	)	)	-RRB-
cord-009615-xcz8m9a7	51	33	.	.	.
cord-009615-xcz8m9a7	52	1	Two	two	CD
cord-009615-xcz8m9a7	52	2	of	of	IN
cord-009615-xcz8m9a7	52	3	the	the	DT
cord-009615-xcz8m9a7	52	4	positive	positive	JJ
cord-009615-xcz8m9a7	52	5	cases	case	NNS
cord-009615-xcz8m9a7	52	6	were	be	VBD
cord-009615-xcz8m9a7	52	7	confirmed	confirm	VBN
cord-009615-xcz8m9a7	52	8	by	by	IN
cord-009615-xcz8m9a7	52	9	direct	direct	JJ
cord-009615-xcz8m9a7	52	10	cloning	cloning	NN
cord-009615-xcz8m9a7	52	11	of	of	IN
cord-009615-xcz8m9a7	52	12	free	free	JJ
cord-009615-xcz8m9a7	52	13	full	full	JJ
cord-009615-xcz8m9a7	52	14	length	length	NN
cord-009615-xcz8m9a7	52	15	JCV	JCV	NNP
cord-009615-xcz8m9a7	52	16	DNA	DNA	NNP
cord-009615-xcz8m9a7	52	17	from	from	IN
cord-009615-xcz8m9a7	52	18	the	the	DT
cord-009615-xcz8m9a7	52	19	infected	infected	JJ
cord-009615-xcz8m9a7	52	20	tissue	tissue	NN
cord-009615-xcz8m9a7	52	21	.	.	.
cord-009615-xcz8m9a7	53	1	In	in	IN
cord-009615-xcz8m9a7	53	2	the	the	DT
cord-009615-xcz8m9a7	53	3	same	same	JJ
cord-009615-xcz8m9a7	53	4	study	study	NN
cord-009615-xcz8m9a7	53	5	,	,	,
cord-009615-xcz8m9a7	53	6	2	2	CD
cord-009615-xcz8m9a7	53	7	of	of	IN
cord-009615-xcz8m9a7	53	8	8	8	CD
cord-009615-xcz8m9a7	53	9	MS	MS	NNP
cord-009615-xcz8m9a7	53	10	brains	brain	NNS
cord-009615-xcz8m9a7	53	11	showed	show	VBD
cord-009615-xcz8m9a7	53	12	evidence	evidence	NN
cord-009615-xcz8m9a7	53	13	of	of	IN
cord-009615-xcz8m9a7	53	14	JCV	JCV	NNP
cord-009615-xcz8m9a7	53	15	DNA	DNA	NNP
cord-009615-xcz8m9a7	53	16	(	(	-LRB-
cord-009615-xcz8m9a7	53	17	57	57	CD
cord-009615-xcz8m9a7	53	18	)	)	-RRB-
cord-009615-xcz8m9a7	53	19	.	.	.
cord-009615-xcz8m9a7	54	1	In	in	IN
cord-009615-xcz8m9a7	54	2	addition	addition	NN
cord-009615-xcz8m9a7	54	3	,	,	,
cord-009615-xcz8m9a7	54	4	18	18	CD
cord-009615-xcz8m9a7	54	5	of	of	IN
cord-009615-xcz8m9a7	54	6	the	the	DT
cord-009615-xcz8m9a7	54	7	19	19	CD
cord-009615-xcz8m9a7	54	8	JCV	JCV	NNP
cord-009615-xcz8m9a7	54	9	-	-	HYPH
cord-009615-xcz8m9a7	54	10	positive	positive	JJ
cord-009615-xcz8m9a7	54	11	brains	brain	NNS
cord-009615-xcz8m9a7	54	12	were	be	VBD
cord-009615-xcz8m9a7	54	13	also	also	RB
cord-009615-xcz8m9a7	54	14	positive	positive	JJ
cord-009615-xcz8m9a7	54	15	for	for	IN
cord-009615-xcz8m9a7	54	16	BKV	BKV	NNP
cord-009615-xcz8m9a7	54	17	DNA	DNA	NNP
cord-009615-xcz8m9a7	54	18	,	,	,
cord-009615-xcz8m9a7	54	19	but	but	CC
cord-009615-xcz8m9a7	54	20	at	at	IN
cord-009615-xcz8m9a7	54	21	much	much	RB
cord-009615-xcz8m9a7	54	22	lower	low	JJR
cord-009615-xcz8m9a7	54	23	levels	level	NNS
cord-009615-xcz8m9a7	54	24	(	(	-LRB-
cord-009615-xcz8m9a7	54	25	57	57	CD
cord-009615-xcz8m9a7	54	26	)	)	-RRB-
cord-009615-xcz8m9a7	54	27	.	.	.
cord-009615-xcz8m9a7	55	1	However	however	RB
cord-009615-xcz8m9a7	55	2	,	,	,
cord-009615-xcz8m9a7	55	3	in	in	IN
cord-009615-xcz8m9a7	55	4	a	a	DT
cord-009615-xcz8m9a7	55	5	fifth	fifth	JJ
cord-009615-xcz8m9a7	55	6	study	study	NN
cord-009615-xcz8m9a7	55	7	PCR	PCR	NNP
cord-009615-xcz8m9a7	55	8	failed	fail	VBD
cord-009615-xcz8m9a7	55	9	to	to	TO
cord-009615-xcz8m9a7	55	10	detect	detect	VB
cord-009615-xcz8m9a7	55	11	JCV	JCV	NNP
cord-009615-xcz8m9a7	55	12	in	in	IN
cord-009615-xcz8m9a7	55	13	DNA	dna	NN
cord-009615-xcz8m9a7	55	14	preparations	preparation	NNS
cord-009615-xcz8m9a7	55	15	from	from	IN
cord-009615-xcz8m9a7	55	16	either	either	CC
cord-009615-xcz8m9a7	55	17	MS	MS	NNP
cord-009615-xcz8m9a7	55	18	or	or	CC
cord-009615-xcz8m9a7	55	19	normal	normal	JJ
cord-009615-xcz8m9a7	55	20	brains	brain	NNS
cord-009615-xcz8m9a7	55	21	(	(	-LRB-
cord-009615-xcz8m9a7	55	22	84	84	CD
cord-009615-xcz8m9a7	55	23	)	)	-RRB-
cord-009615-xcz8m9a7	55	24	.	.	.
cord-009615-xcz8m9a7	56	1	Additional	additional	JJ
cord-009615-xcz8m9a7	56	2	studies	study	NNS
cord-009615-xcz8m9a7	56	3	are	be	VBP
cord-009615-xcz8m9a7	56	4	required	require	VBN
cord-009615-xcz8m9a7	56	5	to	to	TO
cord-009615-xcz8m9a7	56	6	ascertain	ascertain	VB
cord-009615-xcz8m9a7	56	7	the	the	DT
cord-009615-xcz8m9a7	56	8	proportion	proportion	NN
cord-009615-xcz8m9a7	56	9	of	of	IN
cord-009615-xcz8m9a7	56	10	non	non	JJ
cord-009615-xcz8m9a7	56	11	-	-	JJ
cord-009615-xcz8m9a7	56	12	PML	pml	JJ
cord-009615-xcz8m9a7	56	13	brains	brain	NNS
cord-009615-xcz8m9a7	56	14	with	with	IN
cord-009615-xcz8m9a7	56	15	polyomavirus	polyomavirus	JJ
cord-009615-xcz8m9a7	56	16	infection	infection	NN
cord-009615-xcz8m9a7	56	17	and	and	CC
cord-009615-xcz8m9a7	56	18	the	the	DT
cord-009615-xcz8m9a7	56	19	state	state	NN
cord-009615-xcz8m9a7	56	20	of	of	IN
cord-009615-xcz8m9a7	56	21	the	the	DT
cord-009615-xcz8m9a7	56	22	viral	viral	JJ
cord-009615-xcz8m9a7	56	23	DNA	dna	NN
cord-009615-xcz8m9a7	56	24	.	.	.
cord-009615-xcz8m9a7	57	1	In	in	IN
cord-009615-xcz8m9a7	57	2	these	these	DT
cord-009615-xcz8m9a7	57	3	individuals	individual	NNS
cord-009615-xcz8m9a7	57	4	there	there	EX
cord-009615-xcz8m9a7	57	5	was	be	VBD
cord-009615-xcz8m9a7	57	6	no	no	DT
cord-009615-xcz8m9a7	57	7	reported	report	VBN
cord-009615-xcz8m9a7	57	8	evidence	evidence	NN
cord-009615-xcz8m9a7	57	9	for	for	IN
cord-009615-xcz8m9a7	57	10	virus	virus	NN
cord-009615-xcz8m9a7	57	11	particles	particle	NNS
cord-009615-xcz8m9a7	57	12	,	,	,
cord-009615-xcz8m9a7	57	13	nor	nor	CC
cord-009615-xcz8m9a7	57	14	for	for	IN
cord-009615-xcz8m9a7	57	15	JCV	JCV	NNP
cord-009615-xcz8m9a7	57	16	expression	expression	NN
cord-009615-xcz8m9a7	57	17	in	in	IN
cord-009615-xcz8m9a7	57	18	the	the	DT
cord-009615-xcz8m9a7	57	19	brain	brain	NN
cord-009615-xcz8m9a7	57	20	or	or	CC
cord-009615-xcz8m9a7	57	21	neuropathological	neuropathological	JJ
cord-009615-xcz8m9a7	57	22	changes	change	NNS
cord-009615-xcz8m9a7	57	23	attributable	attributable	JJ
cord-009615-xcz8m9a7	57	24	to	to	IN
cord-009615-xcz8m9a7	57	25	the	the	DT
cord-009615-xcz8m9a7	57	26	presence	presence	NN
cord-009615-xcz8m9a7	57	27	of	of	IN
cord-009615-xcz8m9a7	57	28	viral	viral	JJ
cord-009615-xcz8m9a7	57	29	DNA	dna	NN
cord-009615-xcz8m9a7	57	30	.	.	.
cord-009615-xcz8m9a7	58	1	However	however	RB
cord-009615-xcz8m9a7	58	2	,	,	,
cord-009615-xcz8m9a7	58	3	in	in	IN
cord-009615-xcz8m9a7	58	4	another	another	DT
cord-009615-xcz8m9a7	58	5	study	study	NN
cord-009615-xcz8m9a7	58	6	evidence	evidence	NN
cord-009615-xcz8m9a7	58	7	for	for	IN
cord-009615-xcz8m9a7	58	8	JCV	JCV	NNP
cord-009615-xcz8m9a7	58	9	DNA	DNA	NNP
cord-009615-xcz8m9a7	58	10	was	be	VBD
cord-009615-xcz8m9a7	58	11	found	find	VBN
cord-009615-xcz8m9a7	58	12	by	by	IN
cord-009615-xcz8m9a7	58	13	in	in	IN
cord-009615-xcz8m9a7	58	14	situ	situ	NN
cord-009615-xcz8m9a7	58	15	hybridization	hybridization	NN
cord-009615-xcz8m9a7	58	16	in	in	IN
cord-009615-xcz8m9a7	58	17	brains	brain	NNS
cord-009615-xcz8m9a7	58	18	of	of	IN
cord-009615-xcz8m9a7	58	19	3	3	CD
cord-009615-xcz8m9a7	58	20	of	of	IN
cord-009615-xcz8m9a7	58	21	10	10	CD
cord-009615-xcz8m9a7	58	22	elderly	elderly	JJ
cord-009615-xcz8m9a7	58	23	patients	patient	NNS
cord-009615-xcz8m9a7	58	24	without	without	IN
cord-009615-xcz8m9a7	58	25	clinical	clinical	JJ
cord-009615-xcz8m9a7	58	26	PML	PML	NNP
cord-009615-xcz8m9a7	58	27	,	,	,
cord-009615-xcz8m9a7	58	28	but	but	CC
cord-009615-xcz8m9a7	58	29	with	with	IN
cord-009615-xcz8m9a7	58	30	very	very	RB
cord-009615-xcz8m9a7	58	31	small	small	JJ
cord-009615-xcz8m9a7	58	32	foci	foci	NN
cord-009615-xcz8m9a7	58	33	of	of	IN
cord-009615-xcz8m9a7	58	34	demyelination	demyelination	NN
cord-009615-xcz8m9a7	58	35	(	(	-LRB-
cord-009615-xcz8m9a7	58	36	58	58	CD
cord-009615-xcz8m9a7	58	37	)	)	-RRB-
cord-009615-xcz8m9a7	58	38	.	.	.
cord-009615-xcz8m9a7	59	1	It	-PRON-	PRP
cord-009615-xcz8m9a7	59	2	should	should	MD
cord-009615-xcz8m9a7	59	3	be	be	VB
cord-009615-xcz8m9a7	59	4	noted	note	VBN
cord-009615-xcz8m9a7	59	5	that	that	IN
cord-009615-xcz8m9a7	59	6	these	these	DT
cord-009615-xcz8m9a7	59	7	findings	finding	NNS
cord-009615-xcz8m9a7	59	8	could	could	MD
cord-009615-xcz8m9a7	59	9	not	not	RB
cord-009615-xcz8m9a7	59	10	be	be	VB
cord-009615-xcz8m9a7	59	11	reproduced	reproduce	VBN
cord-009615-xcz8m9a7	59	12	in	in	IN
cord-009615-xcz8m9a7	59	13	a	a	DT
cord-009615-xcz8m9a7	59	14	study	study	NN
cord-009615-xcz8m9a7	59	15	of	of	IN
cord-009615-xcz8m9a7	59	16	Alzheimer	Alzheimer	NNP
cord-009615-xcz8m9a7	59	17	's	's	POS
cord-009615-xcz8m9a7	59	18	disease	disease	NN
cord-009615-xcz8m9a7	59	19	brain	brain	NN
cord-009615-xcz8m9a7	59	20	tissue	tissue	NN
cord-009615-xcz8m9a7	59	21	(	(	-LRB-
cord-009615-xcz8m9a7	59	22	85	85	CD
cord-009615-xcz8m9a7	59	23	PML	PML	NNP
cord-009615-xcz8m9a7	59	24	was	be	VBD
cord-009615-xcz8m9a7	59	25	once	once	RB
cord-009615-xcz8m9a7	59	26	an	an	DT
cord-009615-xcz8m9a7	59	27	extremely	extremely	RB
cord-009615-xcz8m9a7	59	28	rare	rare	JJ
cord-009615-xcz8m9a7	59	29	complication	complication	NN
cord-009615-xcz8m9a7	59	30	of	of	IN
cord-009615-xcz8m9a7	59	31	chronic	chronic	JJ
cord-009615-xcz8m9a7	59	32	lymphocytic	lymphocytic	JJ
cord-009615-xcz8m9a7	59	33	leukemia	leukemia	NN
cord-009615-xcz8m9a7	59	34	and	and	CC
cord-009615-xcz8m9a7	59	35	lymphomas	lymphoma	NNS
cord-009615-xcz8m9a7	59	36	,	,	,
cord-009615-xcz8m9a7	59	37	but	but	CC
cord-009615-xcz8m9a7	59	38	now	now	RB
cord-009615-xcz8m9a7	59	39	occurs	occur	VBZ
cord-009615-xcz8m9a7	59	40	in	in	IN
cord-009615-xcz8m9a7	59	41	approximately	approximately	RB
cord-009615-xcz8m9a7	59	42	26	26	CD
cord-009615-xcz8m9a7	59	43	%	%	NN
cord-009615-xcz8m9a7	59	44	(	(	-LRB-
cord-009615-xcz8m9a7	59	45	or	or	CC
cord-009615-xcz8m9a7	59	46	more	more	RBR
cord-009615-xcz8m9a7	59	47	)	)	-RRB-
cord-009615-xcz8m9a7	59	48	of	of	IN
cord-009615-xcz8m9a7	59	49	AIDS	AIDS	NNP
cord-009615-xcz8m9a7	59	50	patients	patient	NNS
cord-009615-xcz8m9a7	59	51	(	(	-LRB-
cord-009615-xcz8m9a7	59	52	87,88	87,88	CD
cord-009615-xcz8m9a7	59	53	)	)	-RRB-
cord-009615-xcz8m9a7	59	54	.	.	.
cord-009615-xcz8m9a7	60	1	The	the	DT
cord-009615-xcz8m9a7	60	2	finding	finding	NN
cord-009615-xcz8m9a7	60	3	of	of	IN
cord-009615-xcz8m9a7	60	4	JCV	JCV	NNP
cord-009615-xcz8m9a7	60	5	DNA	DNA	NNP
cord-009615-xcz8m9a7	60	6	in	in	IN
cord-009615-xcz8m9a7	60	7	normal	normal	JJ
cord-009615-xcz8m9a7	60	8	brains	brain	NNS
cord-009615-xcz8m9a7	60	9	suggests	suggest	VBZ
cord-009615-xcz8m9a7	60	10	that	that	IN
cord-009615-xcz8m9a7	60	11	some	some	DT
cord-009615-xcz8m9a7	60	12	cases	case	NNS
cord-009615-xcz8m9a7	60	13	of	of	IN
cord-009615-xcz8m9a7	60	14	PML	PML	NNP
cord-009615-xcz8m9a7	60	15	,	,	,
cord-009615-xcz8m9a7	60	16	which	which	WDT
cord-009615-xcz8m9a7	60	17	is	be	VBZ
cord-009615-xcz8m9a7	60	18	almost	almost	RB
cord-009615-xcz8m9a7	60	19	exclusively	exclusively	RB
cord-009615-xcz8m9a7	60	20	an	an	DT
cord-009615-xcz8m9a7	60	21	adult	adult	NN
cord-009615-xcz8m9a7	60	22	disease	disease	NN
cord-009615-xcz8m9a7	60	23	,	,	,
cord-009615-xcz8m9a7	60	24	may	may	MD
cord-009615-xcz8m9a7	60	25	represent	represent	VB
cord-009615-xcz8m9a7	60	26	the	the	DT
cord-009615-xcz8m9a7	60	27	reactivation	reactivation	NN
cord-009615-xcz8m9a7	60	28	of	of	IN
cord-009615-xcz8m9a7	60	29	latent	latent	JJ
cord-009615-xcz8m9a7	60	30	viral	viral	JJ
cord-009615-xcz8m9a7	60	31	DNA	dna	NN
cord-009615-xcz8m9a7	60	32	harbored	harbor	VBN
cord-009615-xcz8m9a7	60	33	in	in	IN
cord-009615-xcz8m9a7	60	34	the	the	DT
cord-009615-xcz8m9a7	60	35	brain	brain	NN
cord-009615-xcz8m9a7	60	36	following	follow	VBG
cord-009615-xcz8m9a7	60	37	a	a	DT
cord-009615-xcz8m9a7	60	38	childhood	childhood	NN
cord-009615-xcz8m9a7	60	39	infection	infection	NN
cord-009615-xcz8m9a7	60	40	.	.	.
cord-009615-xcz8m9a7	61	1	When	when	WRB
cord-009615-xcz8m9a7	61	2	PML	PML	NNP
cord-009615-xcz8m9a7	61	3	occurs	occur	VBZ
cord-009615-xcz8m9a7	61	4	in	in	IN
cord-009615-xcz8m9a7	61	5	AIDS	AIDS	NNP
cord-009615-xcz8m9a7	61	6	,	,	,
cord-009615-xcz8m9a7	61	7	it	-PRON-	PRP
cord-009615-xcz8m9a7	61	8	seems	seem	VBZ
cord-009615-xcz8m9a7	61	9	likely	likely	JJ
cord-009615-xcz8m9a7	61	10	that	that	IN
cord-009615-xcz8m9a7	61	11	two	two	CD
cord-009615-xcz8m9a7	61	12	main	main	JJ
cord-009615-xcz8m9a7	61	13	factors	factor	NNS
cord-009615-xcz8m9a7	61	14	combine	combine	VBP
cord-009615-xcz8m9a7	61	15	to	to	TO
cord-009615-xcz8m9a7	61	16	promote	promote	VB
cord-009615-xcz8m9a7	61	17	JCV	JCV	NNP
cord-009615-xcz8m9a7	61	18	reactivation	reactivation	NN
cord-009615-xcz8m9a7	61	19	.	.	.
cord-009615-xcz8m9a7	62	1	First	first	RB
cord-009615-xcz8m9a7	62	2	,	,	,
cord-009615-xcz8m9a7	62	3	there	there	EX
cord-009615-xcz8m9a7	62	4	is	be	VBZ
cord-009615-xcz8m9a7	62	5	the	the	DT
cord-009615-xcz8m9a7	62	6	immunosuppressive	immunosuppressive	JJ
cord-009615-xcz8m9a7	62	7	effect	effect	NN
cord-009615-xcz8m9a7	62	8	of	of	IN
cord-009615-xcz8m9a7	62	9	HIV-1	HIV-1	NNP
cord-009615-xcz8m9a7	62	10	infection	infection	NN
cord-009615-xcz8m9a7	62	11	.	.	.
cord-009615-xcz8m9a7	63	1	In	in	IN
cord-009615-xcz8m9a7	63	2	addition	addition	NN
cord-009615-xcz8m9a7	63	3	,	,	,
cord-009615-xcz8m9a7	63	4	since	since	IN
cord-009615-xcz8m9a7	63	5	the	the	DT
cord-009615-xcz8m9a7	63	6	HIV-1	HIV-1	NNP
cord-009615-xcz8m9a7	63	7	Tat	Tat	NNP
cord-009615-xcz8m9a7	63	8	protein	protein	NN
cord-009615-xcz8m9a7	63	9	can	can	MD
cord-009615-xcz8m9a7	63	10	transactivate	transactivate	VB
cord-009615-xcz8m9a7	63	11	JCV	JCV	NNP
cord-009615-xcz8m9a7	63	12	late	late	JJ
cord-009615-xcz8m9a7	63	13	transcription	transcription	NN
cord-009615-xcz8m9a7	63	14	in	in	IN
cord-009615-xcz8m9a7	63	15	vitro	vitro	FW
cord-009615-xcz8m9a7	63	16	(	(	-LRB-
cord-009615-xcz8m9a7	63	17	89	89	CD
cord-009615-xcz8m9a7	63	18	-	-	SYM
cord-009615-xcz8m9a7	63	19	91	91	CD
cord-009615-xcz8m9a7	63	20	)	)	-RRB-
cord-009615-xcz8m9a7	63	21	,	,	,
cord-009615-xcz8m9a7	63	22	it	-PRON-	PRP
cord-009615-xcz8m9a7	63	23	seems	seem	VBZ
cord-009615-xcz8m9a7	63	24	likely	likely	JJ
cord-009615-xcz8m9a7	63	25	that	that	IN
cord-009615-xcz8m9a7	63	26	Tat	Tat	NNP
cord-009615-xcz8m9a7	63	27	produced	produce	VBN
cord-009615-xcz8m9a7	63	28	by	by	IN
cord-009615-xcz8m9a7	63	29	HIV-1	HIV-1	NNP
cord-009615-xcz8m9a7	63	30	infection	infection	NN
cord-009615-xcz8m9a7	63	31	of	of	IN
cord-009615-xcz8m9a7	63	32	the	the	DT
cord-009615-xcz8m9a7	63	33	CNS	CNS	NNP
cord-009615-xcz8m9a7	63	34	transactivates	transactivate	NNS
cord-009615-xcz8m9a7	63	35	latent	latent	JJ
cord-009615-xcz8m9a7	63	36	JCV	JCV	NNP
cord-009615-xcz8m9a7	63	37	in	in	IN
cord-009615-xcz8m9a7	63	38	the	the	DT
cord-009615-xcz8m9a7	63	39	brain	brain	NN
cord-009615-xcz8m9a7	63	40	.	.	.
cord-009615-xcz8m9a7	64	1	Brain	brain	NN
cord-009615-xcz8m9a7	64	2	tissue	tissue	NN
cord-009615-xcz8m9a7	64	3	doubly	doubly	RB
cord-009615-xcz8m9a7	64	4	infected	infect	VBN
cord-009615-xcz8m9a7	64	5	with	with	IN
cord-009615-xcz8m9a7	64	6	HIV	HIV	NNP
cord-009615-xcz8m9a7	64	7	and	and	CC
cord-009615-xcz8m9a7	64	8	JCV	JCV	NNP
cord-009615-xcz8m9a7	64	9	has	have	VBZ
cord-009615-xcz8m9a7	64	10	been	be	VBN
cord-009615-xcz8m9a7	64	11	observed	observe	VBN
cord-009615-xcz8m9a7	64	12	in	in	IN
cord-009615-xcz8m9a7	64	13	several	several	JJ
cord-009615-xcz8m9a7	64	14	studies	study	NNS
cord-009615-xcz8m9a7	64	15	(	(	-LRB-
cord-009615-xcz8m9a7	64	16	92	92	CD
cord-009615-xcz8m9a7	64	17	-	-	SYM
cord-009615-xcz8m9a7	64	18	94	94	CD
cord-009615-xcz8m9a7	64	19	)	)	-RRB-
cord-009615-xcz8m9a7	64	20	.	.	.
cord-009615-xcz8m9a7	65	1	However	however	RB
cord-009615-xcz8m9a7	65	2	,	,	,
cord-009615-xcz8m9a7	65	3	since	since	IN
cord-009615-xcz8m9a7	65	4	Tat	Tat	NNP
cord-009615-xcz8m9a7	65	5	is	be	VBZ
cord-009615-xcz8m9a7	65	6	a	a	DT
cord-009615-xcz8m9a7	65	7	regulatory	regulatory	JJ
cord-009615-xcz8m9a7	65	8	protein	protein	NN
cord-009615-xcz8m9a7	65	9	expressed	express	VBD
cord-009615-xcz8m9a7	65	10	prior	prior	RB
cord-009615-xcz8m9a7	65	11	to	to	IN
cord-009615-xcz8m9a7	65	12	viral	viral	JJ
cord-009615-xcz8m9a7	65	13	replication	replication	NN
cord-009615-xcz8m9a7	65	14	,	,	,
cord-009615-xcz8m9a7	65	15	HIV	HIV	NNP
cord-009615-xcz8m9a7	65	16	particles	particle	NNS
cord-009615-xcz8m9a7	65	17	need	nee	MD
cord-009615-xcz8m9a7	65	18	not	not	RB
cord-009615-xcz8m9a7	65	19	be	be	VB
cord-009615-xcz8m9a7	65	20	present	present	JJ
cord-009615-xcz8m9a7	65	21	for	for	IN
cord-009615-xcz8m9a7	65	22	Tat	Tat	NNP
cord-009615-xcz8m9a7	65	23	to	to	TO
cord-009615-xcz8m9a7	65	24	be	be	VB
cord-009615-xcz8m9a7	65	25	expressed	express	VBN
cord-009615-xcz8m9a7	65	26	.	.	.
cord-009615-xcz8m9a7	66	1	Furthermore	furthermore	RB
cord-009615-xcz8m9a7	66	2	,	,	,
cord-009615-xcz8m9a7	66	3	there	there	EX
cord-009615-xcz8m9a7	66	4	is	be	VBZ
cord-009615-xcz8m9a7	66	5	no	no	DT
cord-009615-xcz8m9a7	66	6	apparent	apparent	JJ
cord-009615-xcz8m9a7	66	7	requirement	requirement	NN
cord-009615-xcz8m9a7	66	8	for	for	IN
cord-009615-xcz8m9a7	66	9	superinfection	superinfection	NN
cord-009615-xcz8m9a7	66	10	of	of	IN
cord-009615-xcz8m9a7	66	11	JCV	JCV	NNP
cord-009615-xcz8m9a7	66	12	-	-	HYPH
cord-009615-xcz8m9a7	66	13	containing	contain	VBG
cord-009615-xcz8m9a7	66	14	glial	glial	JJ
cord-009615-xcz8m9a7	66	15	cells	cell	NNS
cord-009615-xcz8m9a7	66	16	by	by	IN
cord-009615-xcz8m9a7	66	17	HIV	HIV	NNP
cord-009615-xcz8m9a7	66	18	since	since	IN
cord-009615-xcz8m9a7	66	19	a	a	DT
cord-009615-xcz8m9a7	66	20	single	single	JJ
cord-009615-xcz8m9a7	66	21	HIV	HIV	NNP
cord-009615-xcz8m9a7	66	22	-	-	HYPH
cord-009615-xcz8m9a7	66	23	infected	infect	VBN
cord-009615-xcz8m9a7	66	24	cell	cell	NN
cord-009615-xcz8m9a7	66	25	can	can	MD
cord-009615-xcz8m9a7	66	26	transactivate	transactivate	VB
cord-009615-xcz8m9a7	66	27	as	as	RB
cord-009615-xcz8m9a7	66	28	many	many	JJ
cord-009615-xcz8m9a7	66	29	as	as	IN
cord-009615-xcz8m9a7	66	30	1,000	1,000	CD
cord-009615-xcz8m9a7	66	31	uninfected	uninfected	JJ
cord-009615-xcz8m9a7	66	32	bystander	bystander	NN
cord-009615-xcz8m9a7	66	33	human	human	JJ
cord-009615-xcz8m9a7	66	34	brain	brain	NN
cord-009615-xcz8m9a7	66	35	could	could	MD
cord-009615-xcz8m9a7	66	36	provide	provide	VB
cord-009615-xcz8m9a7	66	37	a	a	DT
cord-009615-xcz8m9a7	66	38	target	target	NN
cord-009615-xcz8m9a7	66	39	for	for	IN
cord-009615-xcz8m9a7	66	40	immunemediated	immunemediated	JJ
cord-009615-xcz8m9a7	66	41	demyelination	demyelination	NN
cord-009615-xcz8m9a7	66	42	.	.	.
cord-009615-xcz8m9a7	67	1	Thus	thus	RB
cord-009615-xcz8m9a7	67	2	,	,	,
cord-009615-xcz8m9a7	67	3	while	while	IN
cord-009615-xcz8m9a7	67	4	PML	PML	NNP
cord-009615-xcz8m9a7	67	5	represents	represent	VBZ
cord-009615-xcz8m9a7	67	6	one	one	CD
cord-009615-xcz8m9a7	67	7	type	type	NN
cord-009615-xcz8m9a7	67	8	of	of	IN
cord-009615-xcz8m9a7	67	9	host	host	NN
cord-009615-xcz8m9a7	67	10	response	response	NN
cord-009615-xcz8m9a7	67	11	to	to	IN
cord-009615-xcz8m9a7	67	12	a	a	DT
cord-009615-xcz8m9a7	67	13	latent	latent	JJ
cord-009615-xcz8m9a7	67	14	virus	virus	NN
cord-009615-xcz8m9a7	67	15	infection	infection	NN
cord-009615-xcz8m9a7	67	16	following	follow	VBG
cord-009615-xcz8m9a7	67	17	immunosuppression	immunosuppression	NN
cord-009615-xcz8m9a7	67	18	and	and	CC
cord-009615-xcz8m9a7	67	19	transactivation	transactivation	NN
cord-009615-xcz8m9a7	67	20	,	,	,
cord-009615-xcz8m9a7	67	21	quite	quite	RB
cord-009615-xcz8m9a7	67	22	another	another	DT
cord-009615-xcz8m9a7	67	23	host	host	NN
cord-009615-xcz8m9a7	67	24	response	response	NN
cord-009615-xcz8m9a7	67	25	to	to	IN
cord-009615-xcz8m9a7	67	26	the	the	DT
cord-009615-xcz8m9a7	67	27	same	same	JJ
cord-009615-xcz8m9a7	67	28	latent	latent	JJ
cord-009615-xcz8m9a7	67	29	virus	virus	NN
cord-009615-xcz8m9a7	67	30	might	may	MD
cord-009615-xcz8m9a7	67	31	involve	involve	VB
cord-009615-xcz8m9a7	67	32	strictly	strictly	RB
cord-009615-xcz8m9a7	67	33	limited	limit	VBN
cord-009615-xcz8m9a7	67	34	viral	viral	JJ
cord-009615-xcz8m9a7	67	35	antigen	antigen	NN
cord-009615-xcz8m9a7	67	36	expression	expression	NN
cord-009615-xcz8m9a7	67	37	,	,	,
cord-009615-xcz8m9a7	67	38	which	which	WDT
cord-009615-xcz8m9a7	67	39	when	when	WRB
cord-009615-xcz8m9a7	67	40	combined	combine	VBN
cord-009615-xcz8m9a7	67	41	with	with	IN
cord-009615-xcz8m9a7	67	42	a	a	DT
cord-009615-xcz8m9a7	67	43	hyperactive	hyperactive	JJ
cord-009615-xcz8m9a7	67	44	immune	immune	JJ
cord-009615-xcz8m9a7	67	45	response	response	NN
cord-009615-xcz8m9a7	67	46	to	to	IN
cord-009615-xcz8m9a7	67	47	CNS	CNS	NNP
cord-009615-xcz8m9a7	67	48	viral	viral	JJ
cord-009615-xcz8m9a7	67	49	antigen	antigen	NN
cord-009615-xcz8m9a7	67	50	,	,	,
cord-009615-xcz8m9a7	67	51	could	could	MD
cord-009615-xcz8m9a7	67	52	lead	lead	VB
cord-009615-xcz8m9a7	67	53	to	to	IN
cord-009615-xcz8m9a7	67	54	demyelinating	demyelinate	VBG
cord-009615-xcz8m9a7	67	55	disease	disease	NN
cord-009615-xcz8m9a7	67	56	(	(	-LRB-
cord-009615-xcz8m9a7	67	57	98	98	CD
cord-009615-xcz8m9a7	67	58	)	)	-RRB-
cord-009615-xcz8m9a7	67	59	.	.	.
cord-009615-xcz8m9a7	68	1	In	in	IN
cord-009615-xcz8m9a7	68	2	the	the	DT
cord-009615-xcz8m9a7	68	3	latent	latent	NN
cord-009615-xcz8m9a7	68	4	-	-	HYPH
cord-009615-xcz8m9a7	68	5	virus	virus	NN
cord-009615-xcz8m9a7	68	6	model	model	NN
cord-009615-xcz8m9a7	68	7	a	a	DT
cord-009615-xcz8m9a7	68	8	viral	viral	JJ
cord-009615-xcz8m9a7	68	9	protein	protein	NN
cord-009615-xcz8m9a7	68	10	,	,	,
cord-009615-xcz8m9a7	68	11	or	or	CC
cord-009615-xcz8m9a7	68	12	possibly	possibly	RB
cord-009615-xcz8m9a7	68	13	a	a	DT
cord-009615-xcz8m9a7	68	14	cellular	cellular	JJ
cord-009615-xcz8m9a7	68	15	protein	protein	NN
cord-009615-xcz8m9a7	68	16	aberrantly	aberrantly	RB
cord-009615-xcz8m9a7	68	17	expressed	express	VBD
cord-009615-xcz8m9a7	68	18	,	,	,
cord-009615-xcz8m9a7	68	19	provides	provide	VBZ
cord-009615-xcz8m9a7	68	20	the	the	DT
cord-009615-xcz8m9a7	68	21	antigenic	antigenic	JJ
cord-009615-xcz8m9a7	68	22	target	target	NN
cord-009615-xcz8m9a7	68	23	.	.	.
cord-009615-xcz8m9a7	69	1	In	in	IN
cord-009615-xcz8m9a7	69	2	addition	addition	NN
cord-009615-xcz8m9a7	69	3	,	,	,
cord-009615-xcz8m9a7	69	4	degenerative	degenerative	JJ
cord-009615-xcz8m9a7	69	5	changes	change	NNS
cord-009615-xcz8m9a7	69	6	in	in	IN
cord-009615-xcz8m9a7	69	7	latently	latently	RB
cord-009615-xcz8m9a7	69	8	infected	infected	JJ
cord-009615-xcz8m9a7	69	9	cells	cell	NNS
cord-009615-xcz8m9a7	69	10	leading	lead	VBG
cord-009615-xcz8m9a7	69	11	to	to	IN
cord-009615-xcz8m9a7	69	12	cell	cell	NN
cord-009615-xcz8m9a7	69	13	death	death	NN
cord-009615-xcz8m9a7	69	14	with	with	IN
cord-009615-xcz8m9a7	69	15	antigen	antigen	NN
cord-009615-xcz8m9a7	69	16	release	release	NN
cord-009615-xcz8m9a7	69	17	can	can	MD
cord-009615-xcz8m9a7	69	18	not	not	RB
cord-009615-xcz8m9a7	69	19	be	be	VB
cord-009615-xcz8m9a7	69	20	excluded	exclude	VBN
cord-009615-xcz8m9a7	69	21	.	.	.
cord-009615-xcz8m9a7	70	1	There	there	EX
cord-009615-xcz8m9a7	70	2	is	be	VBZ
cord-009615-xcz8m9a7	70	3	likely	likely	JJ
cord-009615-xcz8m9a7	70	4	to	to	TO
cord-009615-xcz8m9a7	70	5	be	be	VB
cord-009615-xcz8m9a7	70	6	a	a	DT
cord-009615-xcz8m9a7	70	7	continuum	continuum	NN
cord-009615-xcz8m9a7	70	8	between	between	IN
cord-009615-xcz8m9a7	70	9	latent	latent	JJ
cord-009615-xcz8m9a7	70	10	infections	infection	NNS
cord-009615-xcz8m9a7	70	11	which	which	WDT
cord-009615-xcz8m9a7	70	12	remain	remain	VBP
cord-009615-xcz8m9a7	70	13	entirely	entirely	RB
cord-009615-xcz8m9a7	70	14	quiescent	quiescent	JJ
cord-009615-xcz8m9a7	70	15	on	on	IN
cord-009615-xcz8m9a7	70	16	the	the	DT
cord-009615-xcz8m9a7	70	17	one	one	CD
cord-009615-xcz8m9a7	70	18	hand	hand	NN
cord-009615-xcz8m9a7	70	19	,	,	,
cord-009615-xcz8m9a7	70	20	and	and	CC
cord-009615-xcz8m9a7	70	21	those	those	DT
cord-009615-xcz8m9a7	70	22	which	which	WDT
cord-009615-xcz8m9a7	70	23	progress	progress	VBP
cord-009615-xcz8m9a7	70	24	to	to	IN
cord-009615-xcz8m9a7	70	25	clinically	clinically	RB
cord-009615-xcz8m9a7	70	26	definite	definite	JJ
cord-009615-xcz8m9a7	70	27	demyelinating	demyelinating	JJ
cord-009615-xcz8m9a7	70	28	disease	disease	NN
cord-009615-xcz8m9a7	70	29	on	on	IN
cord-009615-xcz8m9a7	70	30	the	the	DT
cord-009615-xcz8m9a7	70	31	other	other	JJ
cord-009615-xcz8m9a7	70	32	.	.	.
cord-009615-xcz8m9a7	71	1	For	for	IN
cord-009615-xcz8m9a7	71	2	example	example	NN
cord-009615-xcz8m9a7	71	3	,	,	,
cord-009615-xcz8m9a7	71	4	primary	primary	JJ
cord-009615-xcz8m9a7	71	5	demyelination	demyelination	NN
cord-009615-xcz8m9a7	71	6	without	without	IN
cord-009615-xcz8m9a7	71	7	clinical	clinical	JJ
cord-009615-xcz8m9a7	71	8	MS	MS	NNP
cord-009615-xcz8m9a7	71	9	has	have	VBZ
cord-009615-xcz8m9a7	71	10	been	be	VBN
cord-009615-xcz8m9a7	71	11	discovered	discover	VBN
cord-009615-xcz8m9a7	71	12	during	during	IN
cord-009615-xcz8m9a7	71	13	routine	routine	JJ
cord-009615-xcz8m9a7	71	14	pathological	pathological	JJ
cord-009615-xcz8m9a7	71	15	study	study	NN
cord-009615-xcz8m9a7	71	16	at	at	IN
cord-009615-xcz8m9a7	71	17	autopsy	autopsy	JJ
cord-009615-xcz8m9a7	71	18	(	(	-LRB-
cord-009615-xcz8m9a7	71	19	99,100	99,100	CD
cord-009615-xcz8m9a7	71	20	)	)	-RRB-
cord-009615-xcz8m9a7	71	21	.	.	.
cord-009615-xcz8m9a7	72	1	Abnormali	Abnormali	NNP
cord-009615-xcz8m9a7	72	2	-	-	HYPH
cord-009615-xcz8m9a7	72	3	ties	tie	NNS
cord-009615-xcz8m9a7	72	4	on	on	IN
cord-009615-xcz8m9a7	72	5	neuroimaging	neuroimage	VBG
cord-009615-xcz8m9a7	72	6	suggestive	suggestive	JJ
cord-009615-xcz8m9a7	72	7	of	of	IN
cord-009615-xcz8m9a7	72	8	subclinical	subclinical	JJ
cord-009615-xcz8m9a7	72	9	MS	m	NNS
cord-009615-xcz8m9a7	72	10	have	have	VBP
cord-009615-xcz8m9a7	72	11	been	be	VBN
cord-009615-xcz8m9a7	72	12	found	find	VBN
cord-009615-xcz8m9a7	72	13	in	in	IN
cord-009615-xcz8m9a7	72	14	healthy	healthy	JJ
cord-009615-xcz8m9a7	72	15	identical	identical	JJ
cord-009615-xcz8m9a7	72	16	twins	twin	NNS
cord-009615-xcz8m9a7	72	17	(	(	-LRB-
cord-009615-xcz8m9a7	72	18	101	101	CD
cord-009615-xcz8m9a7	72	19	)	)	-RRB-
cord-009615-xcz8m9a7	72	20	and	and	CC
cord-009615-xcz8m9a7	72	21	unaffected	unaffected	JJ
cord-009615-xcz8m9a7	72	22	siblings	sibling	NNS
cord-009615-xcz8m9a7	72	23	of	of	IN
cord-009615-xcz8m9a7	72	24	MS	MS	NNP
cord-009615-xcz8m9a7	72	25	patients	patient	NNS
cord-009615-xcz8m9a7	72	26	(	(	-LRB-
cord-009615-xcz8m9a7	72	27	102	102	CD
cord-009615-xcz8m9a7	72	28	)	)	-RRB-
cord-009615-xcz8m9a7	72	29	,	,	,
cord-009615-xcz8m9a7	72	30	as	as	RB
cord-009615-xcz8m9a7	72	31	well	well	RB
cord-009615-xcz8m9a7	72	32	as	as	IN
cord-009615-xcz8m9a7	72	33	20	20	CD
cord-009615-xcz8m9a7	72	34	%	%	NN
cord-009615-xcz8m9a7	72	35	of	of	IN
cord-009615-xcz8m9a7	72	36	older	old	JJR
cord-009615-xcz8m9a7	72	37	adults	adult	NNS
cord-009615-xcz8m9a7	72	38	(	(	-LRB-
cord-009615-xcz8m9a7	72	39	103	103	CD
cord-009615-xcz8m9a7	72	40	)	)	-RRB-
cord-009615-xcz8m9a7	72	41	.	.	.
cord-009615-xcz8m9a7	73	1	What	what	WP
cord-009615-xcz8m9a7	73	2	would	would	MD
cord-009615-xcz8m9a7	73	3	determine	determine	VB
cord-009615-xcz8m9a7	73	4	whether	whether	IN
cord-009615-xcz8m9a7	73	5	a	a	DT
cord-009615-xcz8m9a7	73	6	latent	latent	JJ
cord-009615-xcz8m9a7	73	7	virus	virus	NN
cord-009615-xcz8m9a7	73	8	infection	infection	NN
cord-009615-xcz8m9a7	73	9	remains	remain	VBZ
cord-009615-xcz8m9a7	73	10	entirely	entirely	RB
cord-009615-xcz8m9a7	73	11	benign	benign	JJ
cord-009615-xcz8m9a7	73	12	,	,	,
cord-009615-xcz8m9a7	73	13	or	or	CC
cord-009615-xcz8m9a7	73	14	erupts	erupt	VBZ
cord-009615-xcz8m9a7	73	15	as	as	IN
cord-009615-xcz8m9a7	73	16	a	a	DT
cord-009615-xcz8m9a7	73	17	chronic	chronic	JJ
cord-009615-xcz8m9a7	73	18	demyelinating	demyelinate	VBG
cord-009615-xcz8m9a7	73	19	disease	disease	NN
cord-009615-xcz8m9a7	73	20	such	such	JJ
cord-009615-xcz8m9a7	73	21	as	as	IN
cord-009615-xcz8m9a7	73	22	MS	MS	NNP
cord-009615-xcz8m9a7	73	23	?	?	.
cord-009615-xcz8m9a7	74	1	The	the	DT
cord-009615-xcz8m9a7	74	2	precise	precise	JJ
cord-009615-xcz8m9a7	74	3	mechanisms	mechanism	NNS
cord-009615-xcz8m9a7	74	4	which	which	WDT
cord-009615-xcz8m9a7	74	5	trigger	trigger	VBP
cord-009615-xcz8m9a7	74	6	JCV	JCV	NNP
cord-009615-xcz8m9a7	74	7	and	and	CC
cord-009615-xcz8m9a7	74	8	BKV	BKV	NNP
cord-009615-xcz8m9a7	74	9	expression	expression	NN
cord-009615-xcz8m9a7	74	10	in	in	IN
cord-009615-xcz8m9a7	74	11	kidney	kidney	NN
cord-009615-xcz8m9a7	74	12	tissues	tissue	NNS
cord-009615-xcz8m9a7	74	13	leading	lead	VBG
cord-009615-xcz8m9a7	74	14	to	to	IN
cord-009615-xcz8m9a7	74	15	virus	virus	NN
cord-009615-xcz8m9a7	74	16	excretion	excretion	NN
cord-009615-xcz8m9a7	74	17	under	under	IN
cord-009615-xcz8m9a7	74	18	certain	certain	JJ
cord-009615-xcz8m9a7	74	19	conditions	condition	NNS
cord-009615-xcz8m9a7	74	20	,	,	,
cord-009615-xcz8m9a7	74	21	e.g.	e.g.	RB
cord-009615-xcz8m9a7	74	22	,	,	,
cord-009615-xcz8m9a7	74	23	late	late	RB
cord-009615-xcz8m9a7	74	24	in	in	IN
cord-009615-xcz8m9a7	74	25	pregnancy	pregnancy	NN
cord-009615-xcz8m9a7	74	26	(	(	-LRB-
cord-009615-xcz8m9a7	74	27	104	104	CD
cord-009615-xcz8m9a7	74	28	)	)	-RRB-
cord-009615-xcz8m9a7	75	1	and	and	CC
cord-009615-xcz8m9a7	75	2	during	during	IN
cord-009615-xcz8m9a7	75	3	immunosuppression	immunosuppression	NN
cord-009615-xcz8m9a7	75	4	(	(	-LRB-
cord-009615-xcz8m9a7	75	5	105	105	CD
cord-009615-xcz8m9a7	75	6	,	,	,
cord-009615-xcz8m9a7	75	7	106	106	CD
cord-009615-xcz8m9a7	75	8	)	)	-RRB-
cord-009615-xcz8m9a7	75	9	are	be	VBP
cord-009615-xcz8m9a7	75	10	not	not	RB
cord-009615-xcz8m9a7	75	11	yet	yet	RB
cord-009615-xcz8m9a7	75	12	understood	understand	VBN
cord-009615-xcz8m9a7	75	13	.	.	.
cord-009615-xcz8m9a7	76	1	Nevertheless	nevertheless	RB
cord-009615-xcz8m9a7	76	2	,	,	,
cord-009615-xcz8m9a7	76	3	it	-PRON-	PRP
cord-009615-xcz8m9a7	76	4	is	be	VBZ
cord-009615-xcz8m9a7	76	5	possible	possible	JJ
cord-009615-xcz8m9a7	76	6	to	to	TO
cord-009615-xcz8m9a7	76	7	suggest	suggest	VB
cord-009615-xcz8m9a7	76	8	a	a	DT
cord-009615-xcz8m9a7	76	9	variety	variety	NN
cord-009615-xcz8m9a7	76	10	of	of	IN
cord-009615-xcz8m9a7	76	11	factors	factor	NNS
cord-009615-xcz8m9a7	76	12	capable	capable	JJ
cord-009615-xcz8m9a7	76	13	of	of	IN
cord-009615-xcz8m9a7	76	14	influencing	influence	VBG
cord-009615-xcz8m9a7	76	15	virus	virus	NN
cord-009615-xcz8m9a7	76	16	expression	expression	NN
cord-009615-xcz8m9a7	76	17	in	in	IN
cord-009615-xcz8m9a7	76	18	human	human	JJ
cord-009615-xcz8m9a7	76	19	glial	glial	NN
cord-009615-xcz8m9a7	76	20	cells	cell	NNS
cord-009615-xcz8m9a7	76	21	.	.	.
cord-009615-xcz8m9a7	77	1	The	the	DT
cord-009615-xcz8m9a7	77	2	following	follow	VBG
cord-009615-xcz8m9a7	77	3	likely	likely	JJ
cord-009615-xcz8m9a7	77	4	factors	factor	NNS
cord-009615-xcz8m9a7	77	5	would	would	MD
cord-009615-xcz8m9a7	77	6	include	include	VB
cord-009615-xcz8m9a7	77	7	intrinsic	intrinsic	JJ
cord-009615-xcz8m9a7	77	8	(	(	-LRB-
cord-009615-xcz8m9a7	77	9	i.e.	i.e.	FW
cord-009615-xcz8m9a7	77	10	,	,	,
cord-009615-xcz8m9a7	77	11	genetics	genetic	NNS
cord-009615-xcz8m9a7	77	12	of	of	IN
cord-009615-xcz8m9a7	77	13	host	host	NN
cord-009615-xcz8m9a7	77	14	and	and	CC
cord-009615-xcz8m9a7	77	15	virus	virus	NN
cord-009615-xcz8m9a7	77	16	)	)	-RRB-
cord-009615-xcz8m9a7	77	17	and	and	CC
cord-009615-xcz8m9a7	77	18	extrinsic	extrinsic	JJ
cord-009615-xcz8m9a7	77	19	(	(	-LRB-
cord-009615-xcz8m9a7	77	20	e.g.	e.g.	RB
cord-009615-xcz8m9a7	77	21	,	,	,
cord-009615-xcz8m9a7	77	22	environmental	environmental	JJ
cord-009615-xcz8m9a7	77	23	)	)	-RRB-
cord-009615-xcz8m9a7	77	24	influences	influence	NNS
cord-009615-xcz8m9a7	77	25	on	on	IN
cord-009615-xcz8m9a7	77	26	the	the	DT
cord-009615-xcz8m9a7	77	27	host	host	NN
cord-009615-xcz8m9a7	77	28	's	's	POS
cord-009615-xcz8m9a7	77	29	immune	immune	JJ
cord-009615-xcz8m9a7	77	30	response	response	NN
cord-009615-xcz8m9a7	77	31	.	.	.
cord-009615-xcz8m9a7	78	1	Genetics	genetic	NNS
cord-009615-xcz8m9a7	78	2	of	of	IN
cord-009615-xcz8m9a7	78	3	the	the	DT
cord-009615-xcz8m9a7	78	4	host	host	NN
cord-009615-xcz8m9a7	78	5	.	.	.
cord-009615-xcz8m9a7	79	1	Animal	animal	NN
cord-009615-xcz8m9a7	79	2	models	model	NNS
cord-009615-xcz8m9a7	79	3	have	have	VBP
cord-009615-xcz8m9a7	79	4	documented	document	VBN
cord-009615-xcz8m9a7	79	5	the	the	DT
cord-009615-xcz8m9a7	79	6	important	important	JJ
cord-009615-xcz8m9a7	79	7	influence	influence	NN
cord-009615-xcz8m9a7	79	8	of	of	IN
cord-009615-xcz8m9a7	79	9	host	host	NN
cord-009615-xcz8m9a7	79	10	genetics	genetic	NNS
cord-009615-xcz8m9a7	79	11	in	in	IN
cord-009615-xcz8m9a7	79	12	determining	determine	VBG
cord-009615-xcz8m9a7	79	13	the	the	DT
cord-009615-xcz8m9a7	79	14	outcome	outcome	NN
cord-009615-xcz8m9a7	79	15	of	of	IN
cord-009615-xcz8m9a7	79	16	virus	virus	NN
cord-009615-xcz8m9a7	79	17	infections	infection	NNS
cord-009615-xcz8m9a7	79	18	(	(	-LRB-
cord-009615-xcz8m9a7	79	19	107	107	CD
cord-009615-xcz8m9a7	79	20	,	,	,
cord-009615-xcz8m9a7	79	21	108	108	CD
cord-009615-xcz8m9a7	79	22	)	)	-RRB-
cord-009615-xcz8m9a7	79	23	.	.	.
cord-009615-xcz8m9a7	80	1	These	these	DT
cord-009615-xcz8m9a7	80	2	genetic	genetic	JJ
cord-009615-xcz8m9a7	80	3	influences	influence	NNS
cord-009615-xcz8m9a7	80	4	most	most	RBS
cord-009615-xcz8m9a7	80	5	likely	likely	RB
cord-009615-xcz8m9a7	80	6	include	include	VBP
cord-009615-xcz8m9a7	80	7	determinants	determinant	NNS
cord-009615-xcz8m9a7	80	8	of	of	IN
cord-009615-xcz8m9a7	80	9	the	the	DT
cord-009615-xcz8m9a7	80	10	specificity	specificity	NN
cord-009615-xcz8m9a7	80	11	,	,	,
cord-009615-xcz8m9a7	80	12	type	type	NN
cord-009615-xcz8m9a7	80	13	and	and	CC
cord-009615-xcz8m9a7	80	14	strength	strength	NN
cord-009615-xcz8m9a7	80	15	of	of	IN
cord-009615-xcz8m9a7	80	16	the	the	DT
cord-009615-xcz8m9a7	80	17	immune	immune	JJ
cord-009615-xcz8m9a7	80	18	response	response	NN
cord-009615-xcz8m9a7	80	19	.	.	.
cord-009615-xcz8m9a7	81	1	They	-PRON-	PRP
cord-009615-xcz8m9a7	81	2	may	may	MD
cord-009615-xcz8m9a7	81	3	in	in	IN
cord-009615-xcz8m9a7	81	4	turn	turn	NN
cord-009615-xcz8m9a7	81	5	control	control	VB
cord-009615-xcz8m9a7	81	6	the	the	DT
cord-009615-xcz8m9a7	81	7	severity	severity	NN
cord-009615-xcz8m9a7	81	8	and	and	CC
cord-009615-xcz8m9a7	81	9	extent	extent	NN
cord-009615-xcz8m9a7	81	10	of	of	IN
cord-009615-xcz8m9a7	81	11	the	the	DT
cord-009615-xcz8m9a7	81	12	primary	primary	JJ
cord-009615-xcz8m9a7	81	13	infection	infection	NN
cord-009615-xcz8m9a7	81	14	and	and	CC
cord-009615-xcz8m9a7	81	15	thus	thus	RB
cord-009615-xcz8m9a7	81	16	the	the	DT
cord-009615-xcz8m9a7	81	17	extent	extent	NN
cord-009615-xcz8m9a7	81	18	of	of	IN
cord-009615-xcz8m9a7	81	19	latency	latency	NN
cord-009615-xcz8m9a7	81	20	in	in	IN
cord-009615-xcz8m9a7	81	21	tissues	tissue	NNS
cord-009615-xcz8m9a7	81	22	,	,	,
cord-009615-xcz8m9a7	81	23	e.g.	e.g.	RB
cord-009615-xcz8m9a7	81	24	,	,	,
cord-009615-xcz8m9a7	81	25	kidney	kidney	NN
cord-009615-xcz8m9a7	81	26	,	,	,
cord-009615-xcz8m9a7	81	27	spleen	spleen	NN
cord-009615-xcz8m9a7	81	28	,	,	,
cord-009615-xcz8m9a7	81	29	bone	bone	NN
cord-009615-xcz8m9a7	81	30	marrow	marrow	NN
cord-009615-xcz8m9a7	81	31	and	and	CC
cord-009615-xcz8m9a7	81	32	brain	brain	NN
cord-009615-xcz8m9a7	81	33	.	.	.
cord-009615-xcz8m9a7	82	1	The	the	DT
cord-009615-xcz8m9a7	82	2	immunogenetic	immunogenetic	JJ
cord-009615-xcz8m9a7	82	3	aspects	aspect	NNS
cord-009615-xcz8m9a7	82	4	of	of	IN
cord-009615-xcz8m9a7	82	5	MS	MS	NNP
cord-009615-xcz8m9a7	82	6	(	(	-LRB-
cord-009615-xcz8m9a7	82	7	109	109	CD
cord-009615-xcz8m9a7	82	8	)	)	-RRB-
cord-009615-xcz8m9a7	82	9	can	can	MD
cord-009615-xcz8m9a7	82	10	be	be	VB
cord-009615-xcz8m9a7	82	11	understood	understand	VBN
cord-009615-xcz8m9a7	82	12	in	in	IN
cord-009615-xcz8m9a7	82	13	this	this	DT
cord-009615-xcz8m9a7	82	14	context	context	NN
cord-009615-xcz8m9a7	82	15	,	,	,
cord-009615-xcz8m9a7	82	16	as	as	RB
cord-009615-xcz8m9a7	82	17	well	well	RB
cord-009615-xcz8m9a7	82	18	as	as	IN
cord-009615-xcz8m9a7	82	19	in	in	IN
cord-009615-xcz8m9a7	82	20	the	the	DT
cord-009615-xcz8m9a7	82	21	context	context	NN
cord-009615-xcz8m9a7	82	22	of	of	IN
cord-009615-xcz8m9a7	82	23	autoimmunity	autoimmunity	NN
cord-009615-xcz8m9a7	82	24	to	to	IN
cord-009615-xcz8m9a7	82	25	MBP	MBP	NNP
cord-009615-xcz8m9a7	82	26	.	.	.
cord-009615-xcz8m9a7	83	1	Genetics	genetic	NNS
cord-009615-xcz8m9a7	83	2	of	of	IN
cord-009615-xcz8m9a7	83	3	the	the	DT
cord-009615-xcz8m9a7	83	4	virus	virus	NN
cord-009615-xcz8m9a7	83	5	.	.	.
cord-009615-xcz8m9a7	84	1	At	at	RB
cord-009615-xcz8m9a7	84	2	least	least	JJS
cord-009615-xcz8m9a7	84	3	two	two	CD
cord-009615-xcz8m9a7	84	4	distinct	distinct	JJ
cord-009615-xcz8m9a7	84	5	genotypes	genotype	NNS
cord-009615-xcz8m9a7	84	6	of	of	IN
cord-009615-xcz8m9a7	84	7	JCV	JCV	NNP
cord-009615-xcz8m9a7	84	8	circulate	circulate	VBP
cord-009615-xcz8m9a7	84	9	in	in	IN
cord-009615-xcz8m9a7	84	10	the	the	DT
cord-009615-xcz8m9a7	84	11	human	human	JJ
cord-009615-xcz8m9a7	84	12	population	population	NN
cord-009615-xcz8m9a7	84	13	(	(	-LRB-
cord-009615-xcz8m9a7	84	14	1	1	CD
cord-009615-xcz8m9a7	84	15	10,111	10,111	CD
cord-009615-xcz8m9a7	84	16	)	)	-RRB-
cord-009615-xcz8m9a7	84	17	.	.	.
cord-009615-xcz8m9a7	85	1	Two	two	CD
cord-009615-xcz8m9a7	85	2	types	type	NNS
cord-009615-xcz8m9a7	85	3	of	of	IN
cord-009615-xcz8m9a7	85	4	JCV	JCV	NNP
cord-009615-xcz8m9a7	85	5	in	in	IN
cord-009615-xcz8m9a7	85	6	the	the	DT
cord-009615-xcz8m9a7	85	7	United	United	NNP
cord-009615-xcz8m9a7	85	8	States	States	NNP
cord-009615-xcz8m9a7	85	9	,	,	,
cord-009615-xcz8m9a7	85	10	termed	term	VBD
cord-009615-xcz8m9a7	85	11	type	type	NN
cord-009615-xcz8m9a7	85	12	1	1	CD
cord-009615-xcz8m9a7	85	13	and	and	CC
cord-009615-xcz8m9a7	85	14	type	type	NN
cord-009615-xcz8m9a7	85	15	2	2	CD
cord-009615-xcz8m9a7	85	16	,	,	,
cord-009615-xcz8m9a7	85	17	have	have	VBP
cord-009615-xcz8m9a7	85	18	been	be	VBN
cord-009615-xcz8m9a7	85	19	identified	identify	VBN
cord-009615-xcz8m9a7	85	20	by	by	IN
cord-009615-xcz8m9a7	85	21	DNA	dna	NN
cord-009615-xcz8m9a7	85	22	coding	coding	NN
cord-009615-xcz8m9a7	85	23	region	region	NN
cord-009615-xcz8m9a7	85	24	sequence	sequence	NN
cord-009615-xcz8m9a7	85	25	data	datum	NNS
cord-009615-xcz8m9a7	85	26	from	from	IN
cord-009615-xcz8m9a7	85	27	11	11	CD
cord-009615-xcz8m9a7	85	28	PML	PML	NNP
cord-009615-xcz8m9a7	85	29	isolates	isolate	NNS
cord-009615-xcz8m9a7	85	30	(	(	-LRB-
cord-009615-xcz8m9a7	85	31	111	111	CD
cord-009615-xcz8m9a7	85	32	)	)	-RRB-
cord-009615-xcz8m9a7	85	33	.	.	.
cord-009615-xcz8m9a7	86	1	While	while	IN
cord-009615-xcz8m9a7	86	2	both	both	DT
cord-009615-xcz8m9a7	86	3	are	be	VBP
cord-009615-xcz8m9a7	86	4	also	also	RB
cord-009615-xcz8m9a7	86	5	present	present	JJ
cord-009615-xcz8m9a7	86	6	in	in	IN
cord-009615-xcz8m9a7	86	7	Europe	Europe	NNP
cord-009615-xcz8m9a7	86	8	,	,	,
cord-009615-xcz8m9a7	86	9	to	to	IN
cord-009615-xcz8m9a7	86	10	date	date	NN
cord-009615-xcz8m9a7	86	11	only	only	RB
cord-009615-xcz8m9a7	86	12	cells	cell	NNS
cord-009615-xcz8m9a7	86	13	with	with	IN
cord-009615-xcz8m9a7	86	14	which	which	WDT
cord-009615-xcz8m9a7	86	15	it	-PRON-	PRP
cord-009615-xcz8m9a7	86	16	is	be	VBZ
cord-009615-xcz8m9a7	86	17	in	in	IN
cord-009615-xcz8m9a7	86	18	contact	contact	NN
cord-009615-xcz8m9a7	86	19	(	(	-LRB-
cord-009615-xcz8m9a7	86	20	95,96	95,96	CD
cord-009615-xcz8m9a7	86	21	)	)	-RRB-
cord-009615-xcz8m9a7	86	22	.	.	.
cord-009615-xcz8m9a7	87	1	As	as	IN
cord-009615-xcz8m9a7	87	2	postulated	postulate	VBN
cord-009615-xcz8m9a7	87	3	from	from	IN
cord-009615-xcz8m9a7	87	4	the	the	DT
cord-009615-xcz8m9a7	87	5	TMEV	TMEV	NNP
cord-009615-xcz8m9a7	87	6	model	model	NN
cord-009615-xcz8m9a7	87	7	(	(	-LRB-
cord-009615-xcz8m9a7	87	8	97	97	CD
cord-009615-xcz8m9a7	87	9	)	)	-RRB-
cord-009615-xcz8m9a7	87	10	,	,	,
cord-009615-xcz8m9a7	87	11	and	and	CC
cord-009615-xcz8m9a7	87	12	in	in	IN
cord-009615-xcz8m9a7	87	13	analogy	analogy	NN
cord-009615-xcz8m9a7	87	14	to	to	IN
cord-009615-xcz8m9a7	87	15	the	the	DT
cord-009615-xcz8m9a7	87	16	prediction	prediction	NN
cord-009615-xcz8m9a7	87	17	derived	derive	VBN
cord-009615-xcz8m9a7	87	18	above	above	RB
cord-009615-xcz8m9a7	87	19	from	from	IN
cord-009615-xcz8m9a7	87	20	the	the	DT
cord-009615-xcz8m9a7	87	21	macaque	macaque	NN
cord-009615-xcz8m9a7	87	22	model	model	NN
cord-009615-xcz8m9a7	87	23	,	,	,
cord-009615-xcz8m9a7	87	24	a	a	DT
cord-009615-xcz8m9a7	87	25	latent	latent	JJ
cord-009615-xcz8m9a7	87	26	polyomavirus	polyomavirus	NN
cord-009615-xcz8m9a7	87	27	infecting	infect	VBG
cord-009615-xcz8m9a7	87	28	the	the	DT
cord-009615-xcz8m9a7	87	29	one	one	CD
cord-009615-xcz8m9a7	87	30	of	of	IN
cord-009615-xcz8m9a7	87	31	these	these	DT
cord-009615-xcz8m9a7	87	32	has	have	VBZ
cord-009615-xcz8m9a7	87	33	been	be	VBN
cord-009615-xcz8m9a7	87	34	found	find	VBN
cord-009615-xcz8m9a7	87	35	in	in	IN
cord-009615-xcz8m9a7	87	36	Asian	asian	JJ
cord-009615-xcz8m9a7	87	37	populations	population	NNS
cord-009615-xcz8m9a7	87	38	(	(	-LRB-
cord-009615-xcz8m9a7	87	39	1	1	CD
cord-009615-xcz8m9a7	87	40	10	10	CD
cord-009615-xcz8m9a7	87	41	)	)	-RRB-
cord-009615-xcz8m9a7	87	42	.	.	.
cord-009615-xcz8m9a7	88	1	Most	Most	JJS
cord-009615-xcz8m9a7	88	2	of	of	IN
cord-009615-xcz8m9a7	88	3	the	the	DT
cord-009615-xcz8m9a7	88	4	DNA	dna	NN
cord-009615-xcz8m9a7	88	5	sequence	sequence	NN
cord-009615-xcz8m9a7	88	6	differences	difference	NNS
cord-009615-xcz8m9a7	88	7	between	between	IN
cord-009615-xcz8m9a7	88	8	JCV	JCV	NNP
cord-009615-xcz8m9a7	88	9	types	type	NNS
cord-009615-xcz8m9a7	88	10	1	1	CD
cord-009615-xcz8m9a7	88	11	and	and	CC
cord-009615-xcz8m9a7	88	12	2	2	CD
cord-009615-xcz8m9a7	88	13	are	be	VBP
cord-009615-xcz8m9a7	88	14	silent	silent	JJ
cord-009615-xcz8m9a7	88	15	,	,	,
cord-009615-xcz8m9a7	88	16	i.e.	i.e.	FW
cord-009615-xcz8m9a7	88	17	,	,	,
cord-009615-xcz8m9a7	88	18	do	do	VBP
cord-009615-xcz8m9a7	88	19	not	not	RB
cord-009615-xcz8m9a7	88	20	cause	cause	VB
cord-009615-xcz8m9a7	88	21	typespecific	typespecific	JJ
cord-009615-xcz8m9a7	88	22	amino	amino	NN
cord-009615-xcz8m9a7	88	23	acid	acid	NN
cord-009615-xcz8m9a7	88	24	substitutions	substitution	NNS
cord-009615-xcz8m9a7	88	25	(	(	-LRB-
cord-009615-xcz8m9a7	88	26	1	1	CD
cord-009615-xcz8m9a7	88	27	11	11	CD
cord-009615-xcz8m9a7	88	28	)	)	-RRB-
cord-009615-xcz8m9a7	88	29	.	.	.
cord-009615-xcz8m9a7	89	1	Thus	thus	RB
cord-009615-xcz8m9a7	89	2	,	,	,
cord-009615-xcz8m9a7	89	3	the	the	DT
cord-009615-xcz8m9a7	89	4	capsid	capsid	NN
cord-009615-xcz8m9a7	89	5	proteins	protein	NNS
cord-009615-xcz8m9a7	89	6	of	of	IN
cord-009615-xcz8m9a7	89	7	the	the	DT
cord-009615-xcz8m9a7	89	8	two	two	CD
cord-009615-xcz8m9a7	89	9	types	type	NNS
cord-009615-xcz8m9a7	89	10	of	of	IN
cord-009615-xcz8m9a7	89	11	JCV	JCV	NNP
cord-009615-xcz8m9a7	89	12	are	be	VBP
cord-009615-xcz8m9a7	89	13	antigenically	antigenically	RB
cord-009615-xcz8m9a7	89	14	similar	similar	JJ
cord-009615-xcz8m9a7	89	15	,	,	,
cord-009615-xcz8m9a7	89	16	and	and	CC
cord-009615-xcz8m9a7	89	17	types	type	NNS
cord-009615-xcz8m9a7	89	18	1	1	CD
cord-009615-xcz8m9a7	89	19	and	and	CC
cord-009615-xcz8m9a7	89	20	2	2	CD
cord-009615-xcz8m9a7	89	21	viruses	virus	NNS
cord-009615-xcz8m9a7	89	22	are	be	VBP
cord-009615-xcz8m9a7	89	23	not	not	RB
cord-009615-xcz8m9a7	89	24	serologically	serologically	RB
cord-009615-xcz8m9a7	89	25	distinguishable	distinguishable	JJ
cord-009615-xcz8m9a7	89	26	.	.	.
cord-009615-xcz8m9a7	90	1	However	however	RB
cord-009615-xcz8m9a7	90	2	,	,	,
cord-009615-xcz8m9a7	90	3	a	a	DT
cord-009615-xcz8m9a7	90	4	few	few	JJ
cord-009615-xcz8m9a7	90	5	type	type	NN
cord-009615-xcz8m9a7	90	6	-	-	HYPH
cord-009615-xcz8m9a7	90	7	specific	specific	JJ
cord-009615-xcz8m9a7	90	8	amino	amino	NN
cord-009615-xcz8m9a7	90	9	acid	acid	NN
cord-009615-xcz8m9a7	90	10	changes	change	NNS
cord-009615-xcz8m9a7	90	11	are	be	VBP
cord-009615-xcz8m9a7	90	12	predicted	predict	VBN
cord-009615-xcz8m9a7	90	13	in	in	IN
cord-009615-xcz8m9a7	90	14	the	the	DT
cord-009615-xcz8m9a7	90	15	C	c	NN
cord-009615-xcz8m9a7	90	16	-	-	HYPH
cord-009615-xcz8m9a7	90	17	terminus	terminus	NN
cord-009615-xcz8m9a7	90	18	of	of	IN
cord-009615-xcz8m9a7	90	19	T	T	NNP
cord-009615-xcz8m9a7	90	20	-	-	HYPH
cord-009615-xcz8m9a7	90	21	antigen	antigen	NNP
cord-009615-xcz8m9a7	90	22	which	which	WDT
cord-009615-xcz8m9a7	90	23	might	may	MD
cord-009615-xcz8m9a7	90	24	have	have	VB
cord-009615-xcz8m9a7	90	25	functional	functional	JJ
cord-009615-xcz8m9a7	90	26	significance	significance	NN
cord-009615-xcz8m9a7	90	27	(	(	-LRB-
cord-009615-xcz8m9a7	90	28	1	1	CD
cord-009615-xcz8m9a7	90	29	11	11	CD
cord-009615-xcz8m9a7	90	30	)	)	-RRB-
cord-009615-xcz8m9a7	90	31	.	.	.
cord-009615-xcz8m9a7	91	1	By	by	IN
cord-009615-xcz8m9a7	91	2	analogy	analogy	NN
cord-009615-xcz8m9a7	91	3	to	to	IN
cord-009615-xcz8m9a7	91	4	SV40	SV40	NNP
cord-009615-xcz8m9a7	91	5	T	T	NNP
cord-009615-xcz8m9a7	91	6	-	-	HYPH
cord-009615-xcz8m9a7	91	7	antigen	antigen	NNP
cord-009615-xcz8m9a7	91	8	(	(	-LRB-
cord-009615-xcz8m9a7	91	9	1	1	CD
cord-009615-xcz8m9a7	91	10	12	12	CD
cord-009615-xcz8m9a7	91	11	)	)	-RRB-
cord-009615-xcz8m9a7	91	12	,	,	,
cord-009615-xcz8m9a7	91	13	the	the	DT
cord-009615-xcz8m9a7	91	14	C	c	NN
cord-009615-xcz8m9a7	91	15	-	-	HYPH
cord-009615-xcz8m9a7	91	16	terminus	terminus	NN
cord-009615-xcz8m9a7	91	17	of	of	IN
cord-009615-xcz8m9a7	91	18	JCV	JCV	NNP
cord-009615-xcz8m9a7	91	19	T	T	NNP
cord-009615-xcz8m9a7	91	20	-	-	HYPH
cord-009615-xcz8m9a7	91	21	antigen	antigen	NNP
cord-009615-xcz8m9a7	91	22	may	may	MD
cord-009615-xcz8m9a7	91	23	contain	contain	VB
cord-009615-xcz8m9a7	91	24	a	a	DT
cord-009615-xcz8m9a7	91	25	hostrange	hostrange	NN
cord-009615-xcz8m9a7	91	26	function	function	NN
cord-009615-xcz8m9a7	91	27	.	.	.
cord-009615-xcz8m9a7	92	1	The	the	DT
cord-009615-xcz8m9a7	92	2	possible	possible	JJ
cord-009615-xcz8m9a7	92	3	existence	existence	NN
cord-009615-xcz8m9a7	92	4	of	of	IN
cord-009615-xcz8m9a7	92	5	distinct	distinct	JJ
cord-009615-xcz8m9a7	92	6	types	type	NNS
cord-009615-xcz8m9a7	92	7	of	of	IN
cord-009615-xcz8m9a7	92	8	JCV	JCV	NNP
cord-009615-xcz8m9a7	92	9	characteristic	characteristic	NN
cord-009615-xcz8m9a7	92	10	of	of	IN
cord-009615-xcz8m9a7	92	11	Northern	Northern	NNP
cord-009615-xcz8m9a7	92	12	Europe	Europe	NNP
cord-009615-xcz8m9a7	92	13	and	and	CC
cord-009615-xcz8m9a7	92	14	Asia	Asia	NNP
cord-009615-xcz8m9a7	92	15	suggests	suggest	VBZ
cord-009615-xcz8m9a7	92	16	that	that	IN
cord-009615-xcz8m9a7	92	17	differing	differ	VBG
cord-009615-xcz8m9a7	92	18	types	type	NNS
cord-009615-xcz8m9a7	92	19	of	of	IN
cord-009615-xcz8m9a7	92	20	a	a	DT
cord-009615-xcz8m9a7	92	21	virus	virus	NN
cord-009615-xcz8m9a7	92	22	circulating	circulate	VBG
cord-009615-xcz8m9a7	92	23	in	in	IN
cord-009615-xcz8m9a7	92	24	European	european	JJ
cord-009615-xcz8m9a7	92	25	and	and	CC
cord-009615-xcz8m9a7	92	26	Japanese	japanese	JJ
cord-009615-xcz8m9a7	92	27	populations	population	NNS
cord-009615-xcz8m9a7	92	28	might	may	MD
cord-009615-xcz8m9a7	92	29	contribute	contribute	VB
cord-009615-xcz8m9a7	92	30	to	to	IN
cord-009615-xcz8m9a7	92	31	the	the	DT
cord-009615-xcz8m9a7	92	32	contrasting	contrast	VBG
cord-009615-xcz8m9a7	92	33	clinical	clinical	JJ
cord-009615-xcz8m9a7	92	34	presentations	presentation	NNS
cord-009615-xcz8m9a7	92	35	of	of	IN
cord-009615-xcz8m9a7	92	36	MS	MS	NNP
cord-009615-xcz8m9a7	92	37	(	(	-LRB-
cord-009615-xcz8m9a7	92	38	1	1	CD
cord-009615-xcz8m9a7	92	39	13	13	CD
cord-009615-xcz8m9a7	92	40	)	)	-RRB-
cord-009615-xcz8m9a7	92	41	,	,	,
cord-009615-xcz8m9a7	92	42	in	in	IN
cord-009615-xcz8m9a7	92	43	addition	addition	NN
cord-009615-xcz8m9a7	92	44	to	to	IN
cord-009615-xcz8m9a7	92	45	the	the	DT
cord-009615-xcz8m9a7	92	46	immunogenetic	immunogenetic	JJ
cord-009615-xcz8m9a7	92	47	differences	difference	NNS
cord-009615-xcz8m9a7	92	48	in	in	IN
cord-009615-xcz8m9a7	92	49	Asian	asian	JJ
cord-009615-xcz8m9a7	92	50	populations	population	NNS
cord-009615-xcz8m9a7	92	51	which	which	WDT
cord-009615-xcz8m9a7	92	52	have	have	VBP
cord-009615-xcz8m9a7	92	53	been	be	VBN
cord-009615-xcz8m9a7	92	54	previously	previously	RB
cord-009615-xcz8m9a7	92	55	invoked	invoke	VBN
cord-009615-xcz8m9a7	92	56	(	(	-LRB-
cord-009615-xcz8m9a7	92	57	114	114	CD
cord-009615-xcz8m9a7	92	58	)	)	-RRB-
cord-009615-xcz8m9a7	92	59	.	.	.
cord-009615-xcz8m9a7	93	1	Small	small	JJ
cord-009615-xcz8m9a7	93	2	DNA	dna	NN
cord-009615-xcz8m9a7	93	3	tumor	tumor	NN
cord-009615-xcz8m9a7	93	4	viruses	virus	NNS
cord-009615-xcz8m9a7	93	5	such	such	JJ
cord-009615-xcz8m9a7	93	6	as	as	IN
cord-009615-xcz8m9a7	93	7	the	the	DT
cord-009615-xcz8m9a7	93	8	polyomaviruses	polyomaviruse	NNS
cord-009615-xcz8m9a7	93	9	have	have	VBP
cord-009615-xcz8m9a7	93	10	a	a	DT
cord-009615-xcz8m9a7	93	11	propensity	propensity	NN
cord-009615-xcz8m9a7	93	12	to	to	TO
cord-009615-xcz8m9a7	93	13	be	be	VB
cord-009615-xcz8m9a7	93	14	integrated	integrate	VBN
cord-009615-xcz8m9a7	93	15	into	into	IN
cord-009615-xcz8m9a7	93	16	host	host	NN
cord-009615-xcz8m9a7	93	17	cell	cell	NN
cord-009615-xcz8m9a7	93	18	DNA	dna	NN
cord-009615-xcz8m9a7	93	19	during	during	IN
cord-009615-xcz8m9a7	93	20	transformation	transformation	NN
cord-009615-xcz8m9a7	93	21	,	,	,
cord-009615-xcz8m9a7	93	22	with	with	IN
cord-009615-xcz8m9a7	93	23	oncogenic	oncogenic	JJ
cord-009615-xcz8m9a7	93	24	effects	effect	NNS
cord-009615-xcz8m9a7	93	25	mediated	mediate	VBN
cord-009615-xcz8m9a7	93	26	by	by	IN
cord-009615-xcz8m9a7	93	27	subsequent	subsequent	JJ
cord-009615-xcz8m9a7	93	28	viral	viral	JJ
cord-009615-xcz8m9a7	93	29	oncogene	oncogene	NN
cord-009615-xcz8m9a7	93	30	(	(	-LRB-
cord-009615-xcz8m9a7	93	31	T	t	NN
cord-009615-xcz8m9a7	93	32	-	-	HYPH
cord-009615-xcz8m9a7	93	33	antigen	antigen	NN
cord-009615-xcz8m9a7	93	34	)	)	-RRB-
cord-009615-xcz8m9a7	93	35	expression	expression	NN
cord-009615-xcz8m9a7	93	36	.	.	.
cord-009615-xcz8m9a7	94	1	If	if	IN
cord-009615-xcz8m9a7	94	2	the	the	DT
cord-009615-xcz8m9a7	94	3	viral	viral	JJ
cord-009615-xcz8m9a7	94	4	agents	agent	NNS
cord-009615-xcz8m9a7	94	5	were	be	VBD
cord-009615-xcz8m9a7	94	6	integrated	integrate	VBN
cord-009615-xcz8m9a7	94	7	into	into	IN
cord-009615-xcz8m9a7	94	8	the	the	DT
cord-009615-xcz8m9a7	94	9	DNA	dna	NN
cord-009615-xcz8m9a7	94	10	of	of	IN
cord-009615-xcz8m9a7	94	11	scattered	scatter	VBN
cord-009615-xcz8m9a7	94	12	glial	glial	JJ
cord-009615-xcz8m9a7	94	13	host	host	NN
cord-009615-xcz8m9a7	94	14	cells	cell	NNS
cord-009615-xcz8m9a7	94	15	early	early	RB
cord-009615-xcz8m9a7	94	16	in	in	IN
cord-009615-xcz8m9a7	94	17	life	life	NN
cord-009615-xcz8m9a7	94	18	(	(	-LRB-
cord-009615-xcz8m9a7	94	19	perhaps	perhaps	RB
cord-009615-xcz8m9a7	94	20	during	during	IN
cord-009615-xcz8m9a7	94	21	early	early	JJ
cord-009615-xcz8m9a7	94	22	brain	brain	NN
cord-009615-xcz8m9a7	94	23	development	development	NN
cord-009615-xcz8m9a7	94	24	)	)	-RRB-
cord-009615-xcz8m9a7	94	25	and	and	CC
cord-009615-xcz8m9a7	94	26	thus	thus	RB
cord-009615-xcz8m9a7	94	27	had	have	VBD
cord-009615-xcz8m9a7	94	28	been	be	VBN
cord-009615-xcz8m9a7	94	29	passed	pass	VBN
cord-009615-xcz8m9a7	94	30	on	on	RP
cord-009615-xcz8m9a7	94	31	to	to	IN
cord-009615-xcz8m9a7	94	32	both	both	DT
cord-009615-xcz8m9a7	94	33	daughter	daughter	NN
cord-009615-xcz8m9a7	94	34	cells	cell	NNS
cord-009615-xcz8m9a7	94	35	during	during	IN
cord-009615-xcz8m9a7	94	36	each	each	DT
cord-009615-xcz8m9a7	94	37	host	host	NN
cord-009615-xcz8m9a7	94	38	cell	cell	NN
cord-009615-xcz8m9a7	94	39	mitosis	mitosis	NN
cord-009615-xcz8m9a7	94	40	,	,	,
cord-009615-xcz8m9a7	94	41	a	a	DT
cord-009615-xcz8m9a7	94	42	ready	ready	JJ
cord-009615-xcz8m9a7	94	43	explanation	explanation	NN
cord-009615-xcz8m9a7	94	44	for	for	IN
cord-009615-xcz8m9a7	94	45	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	94	46	infection	infection	NN
cord-009615-xcz8m9a7	94	47	(	(	-LRB-
cord-009615-xcz8m9a7	94	48	and	and	CC
cord-009615-xcz8m9a7	94	49	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	94	50	lesions	lesion	NNS
cord-009615-xcz8m9a7	94	51	)	)	-RRB-
cord-009615-xcz8m9a7	94	52	would	would	MD
cord-009615-xcz8m9a7	94	53	be	be	VB
cord-009615-xcz8m9a7	94	54	provided	provide	VBN
cord-009615-xcz8m9a7	94	55	.	.	.
cord-009615-xcz8m9a7	95	1	(	(	-LRB-
cord-009615-xcz8m9a7	95	2	However	however	RB
cord-009615-xcz8m9a7	95	3	,	,	,
cord-009615-xcz8m9a7	95	4	free	free	JJ
cord-009615-xcz8m9a7	95	5	viral	viral	JJ
cord-009615-xcz8m9a7	95	6	genomes	genome	NNS
cord-009615-xcz8m9a7	95	7	could	could	MD
cord-009615-xcz8m9a7	95	8	also	also	RB
cord-009615-xcz8m9a7	95	9	be	be	VB
cord-009615-xcz8m9a7	95	10	lineally	lineally	RB
cord-009615-xcz8m9a7	95	11	passed	pass	VBN
cord-009615-xcz8m9a7	95	12	to	to	IN
cord-009615-xcz8m9a7	95	13	daughter	daughter	NN
cord-009615-xcz8m9a7	95	14	cells	cell	NNS
cord-009615-xcz8m9a7	95	15	if	if	IN
cord-009615-xcz8m9a7	95	16	viral	viral	JJ
cord-009615-xcz8m9a7	95	17	replication	replication	NN
cord-009615-xcz8m9a7	95	18	is	be	VBZ
cord-009615-xcz8m9a7	95	19	negatively	negatively	RB
cord-009615-xcz8m9a7	95	20	regulated	regulate	VBN
cord-009615-xcz8m9a7	95	21	by	by	IN
cord-009615-xcz8m9a7	95	22	a	a	DT
cord-009615-xcz8m9a7	95	23	cis	cis	NNP
cord-009615-xcz8m9a7	95	24	-	-	HYPH
cord-009615-xcz8m9a7	95	25	acting	act	VBG
cord-009615-xcz8m9a7	95	26	mechanism	mechanism	NN
cord-009615-xcz8m9a7	95	27	and	and	CC
cord-009615-xcz8m9a7	95	28	restricted	restrict	VBN
cord-009615-xcz8m9a7	95	29	to	to	IN
cord-009615-xcz8m9a7	95	30	once	once	RB
cord-009615-xcz8m9a7	95	31	per	per	IN
cord-009615-xcz8m9a7	95	32	cell	cell	NN
cord-009615-xcz8m9a7	95	33	generation	generation	NN
cord-009615-xcz8m9a7	95	34	(	(	-LRB-
cord-009615-xcz8m9a7	95	35	115	115	CD
cord-009615-xcz8m9a7	95	36	)	)	-RRB-
cord-009615-xcz8m9a7	95	37	)	)	-RRB-
cord-009615-xcz8m9a7	95	38	.	.	.
cord-009615-xcz8m9a7	96	1	Each	each	DT
cord-009615-xcz8m9a7	96	2	focus	focus	NN
cord-009615-xcz8m9a7	96	3	of	of	IN
cord-009615-xcz8m9a7	96	4	infection	infection	NN
cord-009615-xcz8m9a7	96	5	would	would	MD
cord-009615-xcz8m9a7	96	6	represent	represent	VB
cord-009615-xcz8m9a7	96	7	the	the	DT
cord-009615-xcz8m9a7	96	8	progeny	progeny	NN
cord-009615-xcz8m9a7	96	9	of	of	IN
cord-009615-xcz8m9a7	96	10	a	a	DT
cord-009615-xcz8m9a7	96	11	single	single	JJ
cord-009615-xcz8m9a7	96	12	infected	infected	JJ
cord-009615-xcz8m9a7	96	13	precursor	precursor	NN
cord-009615-xcz8m9a7	96	14	cell	cell	NN
cord-009615-xcz8m9a7	96	15	.	.	.
cord-009615-xcz8m9a7	97	1	The	the	DT
cord-009615-xcz8m9a7	97	2	cellular	cellular	JJ
cord-009615-xcz8m9a7	97	3	genes	gene	NNS
cord-009615-xcz8m9a7	97	4	flanking	flank	VBG
cord-009615-xcz8m9a7	97	5	the	the	DT
cord-009615-xcz8m9a7	97	6	insertion	insertion	NN
cord-009615-xcz8m9a7	97	7	site	site	NN
cord-009615-xcz8m9a7	97	8	could	could	MD
cord-009615-xcz8m9a7	97	9	influence	influence	VB
cord-009615-xcz8m9a7	97	10	viral	viral	JJ
cord-009615-xcz8m9a7	97	11	expression	expression	NN
cord-009615-xcz8m9a7	97	12	,	,	,
cord-009615-xcz8m9a7	97	13	and	and	CC
cord-009615-xcz8m9a7	97	14	,	,	,
cord-009615-xcz8m9a7	97	15	in	in	IN
cord-009615-xcz8m9a7	97	16	turn	turn	NN
cord-009615-xcz8m9a7	97	17	,	,	,
cord-009615-xcz8m9a7	97	18	viral	viral	JJ
cord-009615-xcz8m9a7	97	19	promoters	promoter	NNS
cord-009615-xcz8m9a7	97	20	/	/	SYM
cord-009615-xcz8m9a7	97	21	enhancers	enhancer	NNS
cord-009615-xcz8m9a7	97	22	could	could	MD
cord-009615-xcz8m9a7	97	23	alter	alter	VB
cord-009615-xcz8m9a7	97	24	the	the	DT
cord-009615-xcz8m9a7	97	25	expression	expression	NN
cord-009615-xcz8m9a7	97	26	of	of	IN
cord-009615-xcz8m9a7	97	27	nearby	nearby	JJ
cord-009615-xcz8m9a7	97	28	cellular	cellular	JJ
cord-009615-xcz8m9a7	97	29	genes	gene	NNS
cord-009615-xcz8m9a7	97	30	.	.	.
cord-009615-xcz8m9a7	98	1	The	the	DT
cord-009615-xcz8m9a7	98	2	site	site	NN
cord-009615-xcz8m9a7	98	3	of	of	IN
cord-009615-xcz8m9a7	98	4	cleavage	cleavage	NN
cord-009615-xcz8m9a7	98	5	of	of	IN
cord-009615-xcz8m9a7	98	6	the	the	DT
cord-009615-xcz8m9a7	98	7	circular	circular	JJ
cord-009615-xcz8m9a7	98	8	viral	viral	JJ
cord-009615-xcz8m9a7	98	9	genome	genome	NN
cord-009615-xcz8m9a7	98	10	(	(	-LRB-
cord-009615-xcz8m9a7	98	11	5	5	CD
cord-009615-xcz8m9a7	98	12	,	,	,
cord-009615-xcz8m9a7	98	13	130	130	CD
cord-009615-xcz8m9a7	98	14	bp	bp	NN
cord-009615-xcz8m9a7	98	15	for	for	IN
cord-009615-xcz8m9a7	98	16	JCV	JCV	NNP
cord-009615-xcz8m9a7	98	17	(	(	-LRB-
cord-009615-xcz8m9a7	98	18	Mad-1	Mad-1	NNP
cord-009615-xcz8m9a7	98	19	)	)	-RRB-
cord-009615-xcz8m9a7	98	20	(	(	-LRB-
cord-009615-xcz8m9a7	98	21	116	116	CD
cord-009615-xcz8m9a7	98	22	)	)	-RRB-
cord-009615-xcz8m9a7	98	23	)	)	-RRB-
cord-009615-xcz8m9a7	98	24	would	would	MD
cord-009615-xcz8m9a7	98	25	be	be	VB
cord-009615-xcz8m9a7	98	26	important	important	JJ
cord-009615-xcz8m9a7	98	27	,	,	,
cord-009615-xcz8m9a7	98	28	as	as	IN
cord-009615-xcz8m9a7	98	29	interruption	interruption	NN
cord-009615-xcz8m9a7	98	30	of	of	IN
cord-009615-xcz8m9a7	98	31	either	either	CC
cord-009615-xcz8m9a7	98	32	the	the	DT
cord-009615-xcz8m9a7	98	33	regulatory	regulatory	JJ
cord-009615-xcz8m9a7	98	34	region	region	NN
cord-009615-xcz8m9a7	98	35	or	or	CC
cord-009615-xcz8m9a7	98	36	viral	viral	JJ
cord-009615-xcz8m9a7	98	37	early	early	JJ
cord-009615-xcz8m9a7	98	38	coding	code	VBG
cord-009615-xcz8m9a7	98	39	region	region	NN
cord-009615-xcz8m9a7	98	40	would	would	MD
cord-009615-xcz8m9a7	98	41	preclude	preclude	VB
cord-009615-xcz8m9a7	98	42	production	production	NN
cord-009615-xcz8m9a7	98	43	of	of	IN
cord-009615-xcz8m9a7	98	44	an	an	DT
cord-009615-xcz8m9a7	98	45	intact	intact	JJ
cord-009615-xcz8m9a7	98	46	T	t	NN
cord-009615-xcz8m9a7	98	47	-	-	HYPH
cord-009615-xcz8m9a7	98	48	antigen	antigen	NNP
cord-009615-xcz8m9a7	98	49	.	.	.
cord-009615-xcz8m9a7	99	1	A	a	DT
cord-009615-xcz8m9a7	99	2	truncated	truncated	JJ
cord-009615-xcz8m9a7	99	3	polypeptide	polypeptide	NN
cord-009615-xcz8m9a7	99	4	might	may	MD
cord-009615-xcz8m9a7	99	5	,	,	,
cord-009615-xcz8m9a7	99	6	however	however	RB
cord-009615-xcz8m9a7	99	7	,	,	,
cord-009615-xcz8m9a7	99	8	be	be	VB
cord-009615-xcz8m9a7	99	9	sufficient	sufficient	JJ
cord-009615-xcz8m9a7	99	10	to	to	TO
cord-009615-xcz8m9a7	99	11	provide	provide	VB
cord-009615-xcz8m9a7	99	12	an	an	DT
cord-009615-xcz8m9a7	99	13	antigenic	antigenic	JJ
cord-009615-xcz8m9a7	99	14	target	target	NN
cord-009615-xcz8m9a7	99	15	in	in	IN
cord-009615-xcz8m9a7	99	16	glial	glial	JJ
cord-009615-xcz8m9a7	99	17	cells	cell	NNS
cord-009615-xcz8m9a7	99	18	.	.	.
cord-009615-xcz8m9a7	100	1	It	-PRON-	PRP
cord-009615-xcz8m9a7	100	2	can	can	MD
cord-009615-xcz8m9a7	100	3	be	be	VB
cord-009615-xcz8m9a7	100	4	assumed	assume	VBN
cord-009615-xcz8m9a7	100	5	that	that	IN
cord-009615-xcz8m9a7	100	6	virus	virus	NN
cord-009615-xcz8m9a7	100	7	latent	latent	VBN
cord-009615-xcz8m9a7	100	8	in	in	IN
cord-009615-xcz8m9a7	100	9	the	the	DT
cord-009615-xcz8m9a7	100	10	adult	adult	NN
cord-009615-xcz8m9a7	100	11	brain	brain	NN
cord-009615-xcz8m9a7	100	12	may	may	MD
cord-009615-xcz8m9a7	100	13	be	be	VB
cord-009615-xcz8m9a7	100	14	acquired	acquire	VBN
cord-009615-xcz8m9a7	100	15	during	during	IN
cord-009615-xcz8m9a7	100	16	primary	primary	JJ
cord-009615-xcz8m9a7	100	17	infection	infection	NN
cord-009615-xcz8m9a7	100	18	early	early	RB
cord-009615-xcz8m9a7	100	19	in	in	IN
cord-009615-xcz8m9a7	100	20	life	life	NN
cord-009615-xcz8m9a7	100	21	,	,	,
cord-009615-xcz8m9a7	100	22	or	or	CC
cord-009615-xcz8m9a7	100	23	possibly	possibly	RB
cord-009615-xcz8m9a7	100	24	transplacentally	transplacentally	RB
cord-009615-xcz8m9a7	100	25	from	from	IN
cord-009615-xcz8m9a7	100	26	a	a	DT
cord-009615-xcz8m9a7	100	27	mother	mother	NN
cord-009615-xcz8m9a7	100	28	who	who	WP
cord-009615-xcz8m9a7	100	29	reactivates	reactivate	VBZ
cord-009615-xcz8m9a7	100	30	the	the	DT
cord-009615-xcz8m9a7	100	31	virus	virus	NN
cord-009615-xcz8m9a7	100	32	during	during	IN
cord-009615-xcz8m9a7	100	33	pregnancy	pregnancy	NN
cord-009615-xcz8m9a7	100	34	(	(	-LRB-
cord-009615-xcz8m9a7	100	35	104,105	104,105	CD
cord-009615-xcz8m9a7	100	36	)	)	-RRB-
cord-009615-xcz8m9a7	100	37	.	.	.
cord-009615-xcz8m9a7	101	1	Unfortunately	unfortunately	RB
cord-009615-xcz8m9a7	101	2	,	,	,
cord-009615-xcz8m9a7	101	3	primary	primary	JJ
cord-009615-xcz8m9a7	101	4	infection	infection	NN
cord-009615-xcz8m9a7	101	5	in	in	IN
cord-009615-xcz8m9a7	101	6	the	the	DT
cord-009615-xcz8m9a7	101	7	child	child	NN
cord-009615-xcz8m9a7	101	8	is	be	VBZ
cord-009615-xcz8m9a7	101	9	difficult	difficult	JJ
cord-009615-xcz8m9a7	101	10	to	to	TO
cord-009615-xcz8m9a7	101	11	pinpoint	pinpoint	VB
cord-009615-xcz8m9a7	101	12	as	as	IN
cord-009615-xcz8m9a7	101	13	it	-PRON-	PRP
cord-009615-xcz8m9a7	101	14	lacks	lack	VBZ
cord-009615-xcz8m9a7	101	15	known	know	VBN
cord-009615-xcz8m9a7	101	16	disease	disease	NN
cord-009615-xcz8m9a7	101	17	symptoms	symptom	NNS
cord-009615-xcz8m9a7	101	18	and	and	CC
cord-009615-xcz8m9a7	101	19	can	can	MD
cord-009615-xcz8m9a7	101	20	only	only	RB
cord-009615-xcz8m9a7	101	21	be	be	VB
cord-009615-xcz8m9a7	101	22	identified	identify	VBN
cord-009615-xcz8m9a7	101	23	by	by	IN
cord-009615-xcz8m9a7	101	24	seroconversion	seroconversion	NN
cord-009615-xcz8m9a7	101	25	.	.	.
cord-009615-xcz8m9a7	102	1	Maternal	maternal	JJ
cord-009615-xcz8m9a7	102	2	reactivation	reactivation	NN
cord-009615-xcz8m9a7	102	3	with	with	IN
cord-009615-xcz8m9a7	102	4	shedding	shed	VBG
cord-009615-xcz8m9a7	102	5	of	of	IN
cord-009615-xcz8m9a7	102	6	virus	virus	NN
cord-009615-xcz8m9a7	102	7	in	in	IN
cord-009615-xcz8m9a7	102	8	the	the	DT
cord-009615-xcz8m9a7	102	9	urine	urine	NN
cord-009615-xcz8m9a7	102	10	is	be	VBZ
cord-009615-xcz8m9a7	102	11	asymptomatic	asymptomatic	JJ
cord-009615-xcz8m9a7	102	12	as	as	RB
cord-009615-xcz8m9a7	102	13	well	well	RB
cord-009615-xcz8m9a7	102	14	.	.	.
cord-009615-xcz8m9a7	103	1	The	the	DT
cord-009615-xcz8m9a7	103	2	timing	timing	NN
cord-009615-xcz8m9a7	103	3	,	,	,
cord-009615-xcz8m9a7	103	4	duration	duration	NN
cord-009615-xcz8m9a7	103	5	,	,	,
cord-009615-xcz8m9a7	103	6	and	and	CC
cord-009615-xcz8m9a7	103	7	site	site	NN
cord-009615-xcz8m9a7	103	8	of	of	IN
cord-009615-xcz8m9a7	103	9	the	the	DT
cord-009615-xcz8m9a7	103	10	primary	primary	JJ
cord-009615-xcz8m9a7	103	11	infection	infection	NN
cord-009615-xcz8m9a7	103	12	,	,	,
cord-009615-xcz8m9a7	103	13	as	as	RB
cord-009615-xcz8m9a7	103	14	well	well	RB
cord-009615-xcz8m9a7	103	15	as	as	IN
cord-009615-xcz8m9a7	103	16	the	the	DT
cord-009615-xcz8m9a7	103	17	magnitude	magnitude	NN
cord-009615-xcz8m9a7	103	18	of	of	IN
cord-009615-xcz8m9a7	103	19	the	the	DT
cord-009615-xcz8m9a7	103	20	resulting	result	VBG
cord-009615-xcz8m9a7	103	21	viremia	viremia	NN
cord-009615-xcz8m9a7	103	22	,	,	,
cord-009615-xcz8m9a7	103	23	will	will	MD
cord-009615-xcz8m9a7	103	24	be	be	VB
cord-009615-xcz8m9a7	103	25	important	important	JJ
cord-009615-xcz8m9a7	103	26	determinants	determinant	NNS
cord-009615-xcz8m9a7	103	27	of	of	IN
cord-009615-xcz8m9a7	103	28	whether	whether	IN
cord-009615-xcz8m9a7	103	29	and	and	CC
cord-009615-xcz8m9a7	103	30	to	to	TO
cord-009615-xcz8m9a7	103	31	what	what	WDT
cord-009615-xcz8m9a7	103	32	extent	extent	NN
cord-009615-xcz8m9a7	103	33	the	the	DT
cord-009615-xcz8m9a7	103	34	virus	virus	NN
cord-009615-xcz8m9a7	103	35	penetrates	penetrate	VBZ
cord-009615-xcz8m9a7	103	36	the	the	DT
cord-009615-xcz8m9a7	103	37	developing	develop	VBG
cord-009615-xcz8m9a7	103	38	brain	brain	NN
cord-009615-xcz8m9a7	103	39	and	and	CC
cord-009615-xcz8m9a7	103	40	establishes	establish	VBZ
cord-009615-xcz8m9a7	103	41	latency	latency	NN
cord-009615-xcz8m9a7	103	42	,	,	,
cord-009615-xcz8m9a7	103	43	and	and	CC
cord-009615-xcz8m9a7	103	44	will	will	MD
cord-009615-xcz8m9a7	103	45	influence	influence	VB
cord-009615-xcz8m9a7	103	46	the	the	DT
cord-009615-xcz8m9a7	103	47	eventual	eventual	JJ
cord-009615-xcz8m9a7	103	48	outcome	outcome	NN
cord-009615-xcz8m9a7	103	49	of	of	IN
cord-009615-xcz8m9a7	103	50	viral	viral	JJ
cord-009615-xcz8m9a7	103	51	latency	latency	NN
cord-009615-xcz8m9a7	103	52	.	.	.
cord-009615-xcz8m9a7	104	1	In	in	IN
cord-009615-xcz8m9a7	104	2	general	general	JJ
cord-009615-xcz8m9a7	104	3	,	,	,
cord-009615-xcz8m9a7	104	4	for	for	IN
cord-009615-xcz8m9a7	104	5	a	a	DT
cord-009615-xcz8m9a7	104	6	given	give	VBN
cord-009615-xcz8m9a7	104	7	virus	virus	NN
cord-009615-xcz8m9a7	104	8	load	load	NN
cord-009615-xcz8m9a7	104	9	,	,	,
cord-009615-xcz8m9a7	104	10	the	the	DT
cord-009615-xcz8m9a7	104	11	earlier	early	RBR
cord-009615-xcz8m9a7	104	12	in	in	IN
cord-009615-xcz8m9a7	104	13	brain	brain	NN
cord-009615-xcz8m9a7	104	14	development	development	NN
cord-009615-xcz8m9a7	104	15	this	this	DT
cord-009615-xcz8m9a7	104	16	seeding	seeding	NN
cord-009615-xcz8m9a7	104	17	occurs	occur	VBZ
cord-009615-xcz8m9a7	104	18	,	,	,
cord-009615-xcz8m9a7	104	19	the	the	DT
cord-009615-xcz8m9a7	104	20	greater	great	JJR
cord-009615-xcz8m9a7	104	21	the	the	DT
cord-009615-xcz8m9a7	104	22	number	number	NN
cord-009615-xcz8m9a7	104	23	of	of	IN
cord-009615-xcz8m9a7	104	24	daughter	daughter	NN
cord-009615-xcz8m9a7	104	25	cells	cell	NNS
cord-009615-xcz8m9a7	104	26	to	to	TO
cord-009615-xcz8m9a7	104	27	which	which	WDT
cord-009615-xcz8m9a7	104	28	the	the	DT
cord-009615-xcz8m9a7	104	29	viral	viral	JJ
cord-009615-xcz8m9a7	104	30	genome	genome	NN
cord-009615-xcz8m9a7	104	31	could	could	MD
cord-009615-xcz8m9a7	104	32	be	be	VB
cord-009615-xcz8m9a7	104	33	lineally	lineally	RB
cord-009615-xcz8m9a7	104	34	passed	pass	VBN
cord-009615-xcz8m9a7	104	35	.	.	.
cord-009615-xcz8m9a7	105	1	This	this	DT
cord-009615-xcz8m9a7	105	2	is	be	VBZ
cord-009615-xcz8m9a7	105	3	true	true	JJ
cord-009615-xcz8m9a7	105	4	whether	whether	IN
cord-009615-xcz8m9a7	105	5	the	the	DT
cord-009615-xcz8m9a7	105	6	viral	viral	JJ
cord-009615-xcz8m9a7	105	7	DNA	dna	NN
cord-009615-xcz8m9a7	105	8	integrates	integrate	VBZ
cord-009615-xcz8m9a7	105	9	into	into	IN
cord-009615-xcz8m9a7	105	10	host	host	NN
cord-009615-xcz8m9a7	105	11	cell	cell	NN
cord-009615-xcz8m9a7	105	12	DNA	dna	NN
cord-009615-xcz8m9a7	105	13	or	or	CC
cord-009615-xcz8m9a7	105	14	free	free	JJ
cord-009615-xcz8m9a7	105	15	virus	virus	NN
cord-009615-xcz8m9a7	105	16	replicates	replicate	VBZ
cord-009615-xcz8m9a7	105	17	synchronously	synchronously	RB
cord-009615-xcz8m9a7	105	18	with	with	IN
cord-009615-xcz8m9a7	105	19	cell	cell	NN
cord-009615-xcz8m9a7	105	20	DNA	dna	NN
cord-009615-xcz8m9a7	105	21	during	during	IN
cord-009615-xcz8m9a7	105	22	mitosis	mitosis	NN
cord-009615-xcz8m9a7	105	23	.	.	.
cord-009615-xcz8m9a7	106	1	Cell	cell	NN
cord-009615-xcz8m9a7	106	2	types	type	NNS
cord-009615-xcz8m9a7	106	3	targeted	target	VBN
cord-009615-xcz8m9a7	106	4	by	by	IN
cord-009615-xcz8m9a7	106	5	brain	brain	NN
cord-009615-xcz8m9a7	106	6	infection	infection	NN
cord-009615-xcz8m9a7	106	7	.	.	.
cord-009615-xcz8m9a7	107	1	Although	although	IN
cord-009615-xcz8m9a7	107	2	JCV	JCV	NNP
cord-009615-xcz8m9a7	107	3	grows	grow	VBZ
cord-009615-xcz8m9a7	107	4	best	well	RBS
cord-009615-xcz8m9a7	107	5	in	in	IN
cord-009615-xcz8m9a7	107	6	human	human	JJ
cord-009615-xcz8m9a7	107	7	fetal	fetal	JJ
cord-009615-xcz8m9a7	107	8	glial	glial	JJ
cord-009615-xcz8m9a7	107	9	cells	cell	NNS
cord-009615-xcz8m9a7	107	10	,	,	,
cord-009615-xcz8m9a7	107	11	glial	glial	JJ
cord-009615-xcz8m9a7	107	12	cells	cell	NNS
cord-009615-xcz8m9a7	107	13	are	be	VBP
cord-009615-xcz8m9a7	107	14	not	not	RB
cord-009615-xcz8m9a7	107	15	the	the	DT
cord-009615-xcz8m9a7	107	16	exclusive	exclusive	JJ
cord-009615-xcz8m9a7	107	17	target	target	NN
cord-009615-xcz8m9a7	107	18	of	of	IN
cord-009615-xcz8m9a7	107	19	JCV	JCV	NNP
cord-009615-xcz8m9a7	107	20	infection	infection	NN
cord-009615-xcz8m9a7	107	21	in	in	IN
cord-009615-xcz8m9a7	107	22	vivo	vivo	NN
cord-009615-xcz8m9a7	107	23	.	.	.
cord-009615-xcz8m9a7	108	1	Infection	infection	NN
cord-009615-xcz8m9a7	108	2	of	of	IN
cord-009615-xcz8m9a7	108	3	the	the	DT
cord-009615-xcz8m9a7	108	4	kidney	kidney	NN
cord-009615-xcz8m9a7	108	5	(	(	-LRB-
cord-009615-xcz8m9a7	108	6	117	117	CD
cord-009615-xcz8m9a7	108	7	)	)	-RRB-
cord-009615-xcz8m9a7	108	8	,	,	,
cord-009615-xcz8m9a7	108	9	spleen	spleen	NNS
cord-009615-xcz8m9a7	108	10	(	(	-LRB-
cord-009615-xcz8m9a7	108	11	118	118	CD
cord-009615-xcz8m9a7	108	12	)	)	-RRB-
cord-009615-xcz8m9a7	108	13	,	,	,
cord-009615-xcz8m9a7	108	14	and	and	CC
cord-009615-xcz8m9a7	108	15	bone	bone	NN
cord-009615-xcz8m9a7	108	16	marrow	marrow	NN
cord-009615-xcz8m9a7	108	17	(	(	-LRB-
cord-009615-xcz8m9a7	108	18	119	119	CD
cord-009615-xcz8m9a7	108	19	)	)	-RRB-
cord-009615-xcz8m9a7	108	20	is	be	VBZ
cord-009615-xcz8m9a7	108	21	well	well	RB
cord-009615-xcz8m9a7	108	22	documented	document	VBN
cord-009615-xcz8m9a7	108	23	.	.	.
cord-009615-xcz8m9a7	109	1	Within	within	IN
cord-009615-xcz8m9a7	109	2	the	the	DT
cord-009615-xcz8m9a7	109	3	brain	brain	NN
cord-009615-xcz8m9a7	109	4	other	other	JJ
cord-009615-xcz8m9a7	109	5	cell	cell	NN
cord-009615-xcz8m9a7	109	6	types	type	NNS
cord-009615-xcz8m9a7	109	7	may	may	MD
cord-009615-xcz8m9a7	109	8	be	be	VB
cord-009615-xcz8m9a7	109	9	involved	involve	VBN
cord-009615-xcz8m9a7	109	10	.	.	.
cord-009615-xcz8m9a7	110	1	Abortive	abortive	JJ
cord-009615-xcz8m9a7	110	2	granule	granule	NN
cord-009615-xcz8m9a7	110	3	cell	cell	NN
cord-009615-xcz8m9a7	110	4	infection	infection	NN
cord-009615-xcz8m9a7	110	5	has	have	VBZ
cord-009615-xcz8m9a7	110	6	been	be	VBN
cord-009615-xcz8m9a7	110	7	observed	observe	VBN
cord-009615-xcz8m9a7	110	8	in	in	IN
cord-009615-xcz8m9a7	110	9	cerebellar	cerebellar	JJ
cord-009615-xcz8m9a7	110	10	PML	PML	NNP
cord-009615-xcz8m9a7	110	11	(	(	-LRB-
cord-009615-xcz8m9a7	110	12	120	120	CD
cord-009615-xcz8m9a7	110	13	)	)	-RRB-
cord-009615-xcz8m9a7	110	14	.	.	.
cord-009615-xcz8m9a7	111	1	Other	other	JJ
cord-009615-xcz8m9a7	111	2	cell	cell	NN
cord-009615-xcz8m9a7	111	3	types	type	NNS
cord-009615-xcz8m9a7	111	4	infected	infect	VBN
cord-009615-xcz8m9a7	111	5	include	include	VBP
cord-009615-xcz8m9a7	111	6	microglial	microglial	JJ
cord-009615-xcz8m9a7	111	7	cells	cell	NNS
cord-009615-xcz8m9a7	111	8	(	(	-LRB-
cord-009615-xcz8m9a7	111	9	121	121	CD
cord-009615-xcz8m9a7	111	10	)	)	-RRB-
cord-009615-xcz8m9a7	111	11	and	and	CC
cord-009615-xcz8m9a7	111	12	brain	brain	NN
cord-009615-xcz8m9a7	111	13	endothelial	endothelial	NN
cord-009615-xcz8m9a7	111	14	cells	cell	NNS
cord-009615-xcz8m9a7	111	15	(	(	-LRB-
cord-009615-xcz8m9a7	111	16	122	122	CD
cord-009615-xcz8m9a7	111	17	)	)	-RRB-
cord-009615-xcz8m9a7	111	18	.	.	.
cord-009615-xcz8m9a7	112	1	JCV	JCV	NNP
cord-009615-xcz8m9a7	112	2	infection	infection	NN
cord-009615-xcz8m9a7	112	3	has	have	VBZ
cord-009615-xcz8m9a7	112	4	been	be	VBN
cord-009615-xcz8m9a7	112	5	observed	observe	VBN
cord-009615-xcz8m9a7	112	6	in	in	IN
cord-009615-xcz8m9a7	112	7	umbilical	umbilical	JJ
cord-009615-xcz8m9a7	112	8	vein	vein	NN
cord-009615-xcz8m9a7	112	9	endothelial	endothelial	JJ
cord-009615-xcz8m9a7	112	10	cells	cell	NNS
cord-009615-xcz8m9a7	112	11	in	in	IN
cord-009615-xcz8m9a7	112	12	culture	culture	NN
cord-009615-xcz8m9a7	112	13	(	(	-LRB-
cord-009615-xcz8m9a7	112	14	123	123	CD
cord-009615-xcz8m9a7	112	15	)	)	-RRB-
cord-009615-xcz8m9a7	112	16	and	and	CC
cord-009615-xcz8m9a7	112	17	in	in	IN
cord-009615-xcz8m9a7	112	18	vascular	vascular	JJ
cord-009615-xcz8m9a7	112	19	endothelial	endothelial	JJ
cord-009615-xcz8m9a7	112	20	cells	cell	NNS
cord-009615-xcz8m9a7	112	21	of	of	IN
cord-009615-xcz8m9a7	112	22	the	the	DT
cord-009615-xcz8m9a7	112	23	neonatally	neonatally	RB
cord-009615-xcz8m9a7	112	24	infected	infect	VBN
cord-009615-xcz8m9a7	112	25	hamster	hamster	NN
cord-009615-xcz8m9a7	112	26	brain	brain	NN
cord-009615-xcz8m9a7	112	27	(	(	-LRB-
cord-009615-xcz8m9a7	112	28	124	124	CD
cord-009615-xcz8m9a7	112	29	)	)	-RRB-
cord-009615-xcz8m9a7	112	30	.	.	.
cord-009615-xcz8m9a7	113	1	Since	since	IN
cord-009615-xcz8m9a7	113	2	astrocytic	astrocytic	JJ
cord-009615-xcz8m9a7	113	3	endfeet	endfeet	NNP
cord-009615-xcz8m9a7	113	4	contact	contact	NN
cord-009615-xcz8m9a7	113	5	up	up	IN
cord-009615-xcz8m9a7	113	6	to	to	TO
cord-009615-xcz8m9a7	113	7	95	95	CD
cord-009615-xcz8m9a7	113	8	%	%	NN
cord-009615-xcz8m9a7	113	9	of	of	IN
cord-009615-xcz8m9a7	113	10	the	the	DT
cord-009615-xcz8m9a7	113	11	endothelial	endothelial	JJ
cord-009615-xcz8m9a7	113	12	cells	cell	NNS
cord-009615-xcz8m9a7	113	13	of	of	IN
cord-009615-xcz8m9a7	113	14	the	the	DT
cord-009615-xcz8m9a7	113	15	brain	brain	NN
cord-009615-xcz8m9a7	113	16	microvasculature	microvasculature	NN
cord-009615-xcz8m9a7	113	17	(	(	-LRB-
cord-009615-xcz8m9a7	113	18	125	125	CD
cord-009615-xcz8m9a7	113	19	)	)	-RRB-
cord-009615-xcz8m9a7	113	20	,	,	,
cord-009615-xcz8m9a7	113	21	infection	infection	NN
cord-009615-xcz8m9a7	113	22	of	of	IN
cord-009615-xcz8m9a7	113	23	brain	brain	NN
cord-009615-xcz8m9a7	113	24	endothelial	endothelial	NN
cord-009615-xcz8m9a7	113	25	cells	cell	NNS
cord-009615-xcz8m9a7	113	26	following	follow	VBG
cord-009615-xcz8m9a7	113	27	early	early	JJ
cord-009615-xcz8m9a7	113	28	viremia	viremia	NN
cord-009615-xcz8m9a7	113	29	would	would	MD
cord-009615-xcz8m9a7	113	30	provide	provide	VB
cord-009615-xcz8m9a7	113	31	an	an	DT
cord-009615-xcz8m9a7	113	32	avenue	avenue	NN
cord-009615-xcz8m9a7	113	33	for	for	IN
cord-009615-xcz8m9a7	113	34	an	an	DT
cord-009615-xcz8m9a7	113	35	agent	agent	NN
cord-009615-xcz8m9a7	113	36	coming	come	VBG
cord-009615-xcz8m9a7	113	37	from	from	IN
cord-009615-xcz8m9a7	113	38	the	the	DT
cord-009615-xcz8m9a7	113	39	circulation	circulation	NN
cord-009615-xcz8m9a7	113	40	to	to	TO
cord-009615-xcz8m9a7	113	41	reach	reach	VB
cord-009615-xcz8m9a7	113	42	astrocytes	astrocyte	NNS
cord-009615-xcz8m9a7	113	43	,	,	,
cord-009615-xcz8m9a7	113	44	and	and	CC
cord-009615-xcz8m9a7	113	45	after	after	IN
cord-009615-xcz8m9a7	113	46	replication	replication	NN
cord-009615-xcz8m9a7	113	47	,	,	,
cord-009615-xcz8m9a7	113	48	to	to	TO
cord-009615-xcz8m9a7	113	49	infect	infect	VB
cord-009615-xcz8m9a7	113	50	surrounding	surround	VBG
cord-009615-xcz8m9a7	113	51	oligodendrocytes	oligodendrocyte	NNS
cord-009615-xcz8m9a7	113	52	.	.	.
cord-009615-xcz8m9a7	114	1	Macaque	Macaque	NNP
cord-009615-xcz8m9a7	114	2	PML	PML	NNP
cord-009615-xcz8m9a7	114	3	brain	brain	NN
cord-009615-xcz8m9a7	114	4	showed	show	VBD
cord-009615-xcz8m9a7	114	5	several	several	JJ
cord-009615-xcz8m9a7	114	6	isolated	isolate	VBN
cord-009615-xcz8m9a7	114	7	clusters	cluster	NNS
cord-009615-xcz8m9a7	114	8	of	of	IN
cord-009615-xcz8m9a7	114	9	SV40-infected	sv40-infected	JJ
cord-009615-xcz8m9a7	114	10	oligodendrocytes	oligodendrocyte	NNS
cord-009615-xcz8m9a7	114	11	around	around	IN
cord-009615-xcz8m9a7	114	12	an	an	DT
cord-009615-xcz8m9a7	114	13	infected	infected	JJ
cord-009615-xcz8m9a7	114	14	astrocyte	astrocyte	NN
cord-009615-xcz8m9a7	114	15	(	(	-LRB-
cord-009615-xcz8m9a7	114	16	Fig	fig	NN
cord-009615-xcz8m9a7	114	17	.	.	.
cord-009615-xcz8m9a7	114	18	3	3	CD
cord-009615-xcz8m9a7	114	19	)	)	-RRB-
cord-009615-xcz8m9a7	114	20	.	.	.
cord-009615-xcz8m9a7	115	1	Although	although	IN
cord-009615-xcz8m9a7	115	2	other	other	JJ
cord-009615-xcz8m9a7	115	3	interpretations	interpretation	NNS
cord-009615-xcz8m9a7	115	4	are	be	VBP
cord-009615-xcz8m9a7	115	5	possible	possible	JJ
cord-009615-xcz8m9a7	115	6	,	,	,
cord-009615-xcz8m9a7	115	7	this	this	DT
cord-009615-xcz8m9a7	115	8	unique	unique	JJ
cord-009615-xcz8m9a7	115	9	array	array	NN
cord-009615-xcz8m9a7	115	10	is	be	VBZ
cord-009615-xcz8m9a7	115	11	best	well	RBS
cord-009615-xcz8m9a7	115	12	explained	explain	VBN
cord-009615-xcz8m9a7	115	13	by	by	IN
cord-009615-xcz8m9a7	115	14	direct	direct	JJ
cord-009615-xcz8m9a7	115	15	passage	passage	NN
cord-009615-xcz8m9a7	115	16	of	of	IN
cord-009615-xcz8m9a7	115	17	virus	virus	NN
cord-009615-xcz8m9a7	115	18	from	from	IN
cord-009615-xcz8m9a7	115	19	the	the	DT
cord-009615-xcz8m9a7	115	20	centrally	centrally	RB
cord-009615-xcz8m9a7	115	21	located	locate	VBN
cord-009615-xcz8m9a7	115	22	astrocyte	astrocyte	NN
cord-009615-xcz8m9a7	115	23	to	to	IN
cord-009615-xcz8m9a7	115	24	the	the	DT
cord-009615-xcz8m9a7	115	25	surrounding	surround	VBG
cord-009615-xcz8m9a7	115	26	oligodendrocytes	oligodendrocyte	NNS
cord-009615-xcz8m9a7	115	27	which	which	WDT
cord-009615-xcz8m9a7	115	28	it	-PRON-	PRP
cord-009615-xcz8m9a7	115	29	contacts	contact	VBZ
cord-009615-xcz8m9a7	115	30	.	.	.
cord-009615-xcz8m9a7	116	1	In	in	IN
cord-009615-xcz8m9a7	116	2	human	human	JJ
cord-009615-xcz8m9a7	116	3	PML	PML	NNP
cord-009615-xcz8m9a7	116	4	brain	brain	NN
cord-009615-xcz8m9a7	116	5	clusters	cluster	NNS
cord-009615-xcz8m9a7	116	6	of	of	IN
cord-009615-xcz8m9a7	116	7	a	a	DT
cord-009615-xcz8m9a7	116	8	few	few	JJ
cord-009615-xcz8m9a7	116	9	enlarged	enlarged	JJ
cord-009615-xcz8m9a7	116	10	oligodendrocytes	oligodendrocyte	NNS
cord-009615-xcz8m9a7	116	11	have	have	VBP
cord-009615-xcz8m9a7	116	12	been	be	VBN
cord-009615-xcz8m9a7	116	13	described	describe	VBN
cord-009615-xcz8m9a7	116	14	as	as	IN
cord-009615-xcz8m9a7	116	15	the	the	DT
cord-009615-xcz8m9a7	116	16	earliest	early	JJS
cord-009615-xcz8m9a7	116	17	recognizable	recognizable	JJ
cord-009615-xcz8m9a7	116	18	microscopic	microscopic	JJ
cord-009615-xcz8m9a7	116	19	lesion	lesion	NN
cord-009615-xcz8m9a7	116	20	(	(	-LRB-
cord-009615-xcz8m9a7	116	21	128,129	128,129	CD
cord-009615-xcz8m9a7	116	22	)	)	-RRB-
cord-009615-xcz8m9a7	116	23	.	.	.
cord-009615-xcz8m9a7	117	1	They	-PRON-	PRP
cord-009615-xcz8m9a7	117	2	created	create	VBD
cord-009615-xcz8m9a7	117	3	demyelinated	demyelinate	VBN
cord-009615-xcz8m9a7	117	4	foci	foci	NN
cord-009615-xcz8m9a7	117	5	of	of	IN
cord-009615-xcz8m9a7	117	6	pinhead	pinhead	NN
cord-009615-xcz8m9a7	117	7	size	size	NN
cord-009615-xcz8m9a7	117	8	(	(	-LRB-
cord-009615-xcz8m9a7	117	9	130	130	CD
cord-009615-xcz8m9a7	117	10	)	)	-RRB-
cord-009615-xcz8m9a7	117	11	,	,	,
cord-009615-xcz8m9a7	117	12	usualIy	usualIy	NNP
cord-009615-xcz8m9a7	117	13	1	1	CD
cord-009615-xcz8m9a7	117	14	to	to	IN
cord-009615-xcz8m9a7	117	15	2	2	CD
cord-009615-xcz8m9a7	117	16	millimeters	millimeter	NNS
cord-009615-xcz8m9a7	117	17	(	(	-LRB-
cord-009615-xcz8m9a7	117	18	mm	mm	NNP
cord-009615-xcz8m9a7	117	19	)	)	-RRB-
cord-009615-xcz8m9a7	117	20	in	in	IN
cord-009615-xcz8m9a7	117	21	diameter	diameter	NN
cord-009615-xcz8m9a7	117	22	(	(	-LRB-
cord-009615-xcz8m9a7	117	23	128,129	128,129	CD
cord-009615-xcz8m9a7	117	24	)	)	-RRB-
cord-009615-xcz8m9a7	117	25	,	,	,
cord-009615-xcz8m9a7	117	26	but	but	CC
cord-009615-xcz8m9a7	117	27	sometimes	sometimes	RB
cord-009615-xcz8m9a7	117	28	as	as	RB
cord-009615-xcz8m9a7	117	29	small	small	JJ
cord-009615-xcz8m9a7	117	30	as	as	IN
cord-009615-xcz8m9a7	117	31	0.1	0.1	CD
cord-009615-xcz8m9a7	117	32	to	to	TO
cord-009615-xcz8m9a7	117	33	0.5	0.5	CD
cord-009615-xcz8m9a7	117	34	mm	mm	NN
cord-009615-xcz8m9a7	117	35	(	(	-LRB-
cord-009615-xcz8m9a7	117	36	131,132	131,132	CD
cord-009615-xcz8m9a7	117	37	)	)	-RRB-
cord-009615-xcz8m9a7	117	38	.	.	.
cord-009615-xcz8m9a7	118	1	In	in	IN
cord-009615-xcz8m9a7	118	2	these	these	DT
cord-009615-xcz8m9a7	118	3	lesions	lesion	NNS
cord-009615-xcz8m9a7	118	4	small	small	JJ
cord-009615-xcz8m9a7	118	5	blood	blood	NN
cord-009615-xcz8m9a7	118	6	vessels	vessel	NNS
cord-009615-xcz8m9a7	118	7	were	be	VBD
cord-009615-xcz8m9a7	118	8	often	often	RB
cord-009615-xcz8m9a7	118	9	seen	see	VBN
cord-009615-xcz8m9a7	118	10	(	(	-LRB-
cord-009615-xcz8m9a7	118	11	129,131,132	129,131,132	CD
cord-009615-xcz8m9a7	118	12	)	)	-RRB-
cord-009615-xcz8m9a7	118	13	,	,	,
cord-009615-xcz8m9a7	118	14	although	although	IN
cord-009615-xcz8m9a7	118	15	no	no	DT
cord-009615-xcz8m9a7	118	16	consistent	consistent	JJ
cord-009615-xcz8m9a7	118	17	perivascular	perivascular	JJ
cord-009615-xcz8m9a7	118	18	location	location	NN
cord-009615-xcz8m9a7	118	19	was	be	VBD
cord-009615-xcz8m9a7	118	20	proved	prove	VBN
cord-009615-xcz8m9a7	118	21	.	.	.
cord-009615-xcz8m9a7	119	1	Giant	giant	JJ
cord-009615-xcz8m9a7	119	2	astrocytes	astrocyte	NNS
cord-009615-xcz8m9a7	119	3	in	in	IN
cord-009615-xcz8m9a7	119	4	PML	PML	NNP
cord-009615-xcz8m9a7	119	5	lesions	lesion	NNS
cord-009615-xcz8m9a7	119	6	have	have	VBP
cord-009615-xcz8m9a7	119	7	been	be	VBN
cord-009615-xcz8m9a7	119	8	observed	observe	VBN
cord-009615-xcz8m9a7	119	9	with	with	IN
cord-009615-xcz8m9a7	119	10	a	a	DT
cord-009615-xcz8m9a7	119	11	cellular	cellular	JJ
cord-009615-xcz8m9a7	119	12	process	process	NN
cord-009615-xcz8m9a7	119	13	attached	attach	VBN
cord-009615-xcz8m9a7	119	14	to	to	IN
cord-009615-xcz8m9a7	119	15	the	the	DT
cord-009615-xcz8m9a7	119	16	wall	wall	NN
cord-009615-xcz8m9a7	119	17	of	of	IN
cord-009615-xcz8m9a7	119	18	an	an	DT
cord-009615-xcz8m9a7	119	19	adjacent	adjacent	JJ
cord-009615-xcz8m9a7	119	20	blood	blood	NN
cord-009615-xcz8m9a7	119	21	vessel	vessel	NN
cord-009615-xcz8m9a7	119	22	(	(	-LRB-
cord-009615-xcz8m9a7	119	23	133	133	CD
cord-009615-xcz8m9a7	119	24	)	)	-RRB-
cord-009615-xcz8m9a7	119	25	.	.	.
cord-009615-xcz8m9a7	120	1	In	in	IN
cord-009615-xcz8m9a7	120	2	one	one	CD
cord-009615-xcz8m9a7	120	3	study	study	NN
cord-009615-xcz8m9a7	120	4	intracytoplasmic	intracytoplasmic	JJ
cord-009615-xcz8m9a7	120	5	clusters	cluster	NNS
cord-009615-xcz8m9a7	120	6	of	of	IN
cord-009615-xcz8m9a7	120	7	JCV	JCV	NNP
cord-009615-xcz8m9a7	120	8	particles	particle	NNS
cord-009615-xcz8m9a7	120	9	were	be	VBD
cord-009615-xcz8m9a7	120	10	observed	observe	VBN
cord-009615-xcz8m9a7	120	11	by	by	IN
cord-009615-xcz8m9a7	120	12	electron	electron	NN
cord-009615-xcz8m9a7	120	13	microscopy	microscopy	NN
cord-009615-xcz8m9a7	120	14	in	in	IN
cord-009615-xcz8m9a7	120	15	infected	infected	JJ
cord-009615-xcz8m9a7	120	16	astrocytes	astrocyte	NNS
cord-009615-xcz8m9a7	120	17	,	,	,
cord-009615-xcz8m9a7	120	18	sometimes	sometimes	RB
cord-009615-xcz8m9a7	120	19	near	near	IN
cord-009615-xcz8m9a7	120	20	foot	foot	NN
cord-009615-xcz8m9a7	120	21	processes	process	NNS
cord-009615-xcz8m9a7	120	22	(	(	-LRB-
cord-009615-xcz8m9a7	120	23	134	134	CD
cord-009615-xcz8m9a7	120	24	)	)	-RRB-
cord-009615-xcz8m9a7	120	25	.	.	.
cord-009615-xcz8m9a7	121	1	These	these	DT
cord-009615-xcz8m9a7	121	2	might	may	MD
cord-009615-xcz8m9a7	121	3	be	be	VB
cord-009615-xcz8m9a7	121	4	passed	pass	VBN
cord-009615-xcz8m9a7	121	5	to	to	IN
cord-009615-xcz8m9a7	121	6	susceptible	susceptible	JJ
cord-009615-xcz8m9a7	121	7	oligodendrocytes	oligodendrocyte	NNS
cord-009615-xcz8m9a7	121	8	,	,	,
cord-009615-xcz8m9a7	121	9	although	although	IN
cord-009615-xcz8m9a7	121	10	in	in	IN
cord-009615-xcz8m9a7	121	11	late	late	JJ
cord-009615-xcz8m9a7	121	12	stages	stage	NNS
cord-009615-xcz8m9a7	121	13	of	of	IN
cord-009615-xcz8m9a7	121	14	disease	disease	NN
cord-009615-xcz8m9a7	121	15	such	such	JJ
cord-009615-xcz8m9a7	121	16	intracytoplasmic	intracytoplasmic	JJ
cord-009615-xcz8m9a7	121	17	particles	particle	NNS
cord-009615-xcz8m9a7	121	18	can	can	MD
cord-009615-xcz8m9a7	121	19	also	also	RB
cord-009615-xcz8m9a7	121	20	be	be	VB
cord-009615-xcz8m9a7	121	21	interpreted	interpret	VBN
cord-009615-xcz8m9a7	121	22	as	as	IN
cord-009615-xcz8m9a7	121	23	an	an	DT
cord-009615-xcz8m9a7	121	24	early	early	JJ
cord-009615-xcz8m9a7	121	25	step	step	NN
cord-009615-xcz8m9a7	121	26	in	in	IN
cord-009615-xcz8m9a7	121	27	astrocyte	astrocyte	JJ
cord-009615-xcz8m9a7	121	28	infection	infection	NN
cord-009615-xcz8m9a7	121	29	by	by	IN
cord-009615-xcz8m9a7	121	30	virions	virion	NNS
cord-009615-xcz8m9a7	121	31	taken	take	VBN
cord-009615-xcz8m9a7	121	32	up	up	RP
cord-009615-xcz8m9a7	121	33	from	from	IN
cord-009615-xcz8m9a7	121	34	surrounding	surround	VBG
cord-009615-xcz8m9a7	121	35	cell	cell	NN
cord-009615-xcz8m9a7	121	36	debris	debris	NN
cord-009615-xcz8m9a7	121	37	(	(	-LRB-
cord-009615-xcz8m9a7	121	38	135	135	CD
cord-009615-xcz8m9a7	121	39	)	)	-RRB-
cord-009615-xcz8m9a7	121	40	.	.	.
cord-009615-xcz8m9a7	122	1	The	the	DT
cord-009615-xcz8m9a7	122	2	presence	presence	NN
cord-009615-xcz8m9a7	122	3	of	of	IN
cord-009615-xcz8m9a7	122	4	small	small	JJ
cord-009615-xcz8m9a7	122	5	clusters	cluster	NNS
cord-009615-xcz8m9a7	122	6	of	of	IN
cord-009615-xcz8m9a7	122	7	infected	infected	JJ
cord-009615-xcz8m9a7	122	8	oligodendrocytes	oligodendrocyte	NNS
cord-009615-xcz8m9a7	122	9	in	in	IN
cord-009615-xcz8m9a7	122	10	the	the	DT
cord-009615-xcz8m9a7	122	11	human	human	JJ
cord-009615-xcz8m9a7	122	12	PML	PML	NNP
cord-009615-xcz8m9a7	122	13	brain	brain	NN
cord-009615-xcz8m9a7	122	14	can	can	MD
cord-009615-xcz8m9a7	122	15	be	be	VB
cord-009615-xcz8m9a7	122	16	interpreted	interpret	VBN
cord-009615-xcz8m9a7	122	17	in	in	IN
cord-009615-xcz8m9a7	122	18	one	one	CD
cord-009615-xcz8m9a7	122	19	of	of	IN
cord-009615-xcz8m9a7	122	20	the	the	DT
cord-009615-xcz8m9a7	122	21	following	follow	VBG
cord-009615-xcz8m9a7	122	22	ways	way	NNS
cord-009615-xcz8m9a7	122	23	.	.	.
cord-009615-xcz8m9a7	123	1	Firstly	firstly	RB
cord-009615-xcz8m9a7	123	2	,	,	,
cord-009615-xcz8m9a7	123	3	the	the	DT
cord-009615-xcz8m9a7	123	4	characteristic	characteristic	JJ
cord-009615-xcz8m9a7	123	5	pinpoint	pinpoint	NN
cord-009615-xcz8m9a7	123	6	foci	foci	NN
cord-009615-xcz8m9a7	123	7	of	of	IN
cord-009615-xcz8m9a7	123	8	demyelination	demyelination	NN
cord-009615-xcz8m9a7	123	9	in	in	IN
cord-009615-xcz8m9a7	123	10	a	a	DT
cord-009615-xcz8m9a7	123	11	b	b	NN
cord-009615-xcz8m9a7	123	12	Figure	figure	NN
cord-009615-xcz8m9a7	123	13	3	3	CD
cord-009615-xcz8m9a7	123	14	Clusters	cluster	NNS
cord-009615-xcz8m9a7	123	15	of	of	IN
cord-009615-xcz8m9a7	123	16	simian	simian	JJ
cord-009615-xcz8m9a7	123	17	virus	virus	NN
cord-009615-xcz8m9a7	123	18	40	40	CD
cord-009615-xcz8m9a7	123	19	(	(	-LRB-
cord-009615-xcz8m9a7	123	20	SV40)-infected	SV40)-infected	NNP
cord-009615-xcz8m9a7	123	21	oligodendrocytes	oligodendrocyte	NNS
cord-009615-xcz8m9a7	123	22	surround	surround	VBP
cord-009615-xcz8m9a7	123	23	an	an	DT
cord-009615-xcz8m9a7	123	24	infected	infected	JJ
cord-009615-xcz8m9a7	123	25	astrocyte	astrocyte	NN
cord-009615-xcz8m9a7	123	26	in	in	IN
cord-009615-xcz8m9a7	123	27	the	the	DT
cord-009615-xcz8m9a7	123	28	macaque	macaque	NN
cord-009615-xcz8m9a7	123	29	brain	brain	NN
cord-009615-xcz8m9a7	123	30	.	.	.
cord-009615-xcz8m9a7	124	1	a	a	DT
cord-009615-xcz8m9a7	124	2	Note	note	NN
cord-009615-xcz8m9a7	124	3	the	the	DT
cord-009615-xcz8m9a7	124	4	immunostained	immunostained	JJ
cord-009615-xcz8m9a7	124	5	astrocyte	astrocyte	NNP
cord-009615-xcz8m9a7	124	6	process	process	NN
cord-009615-xcz8m9a7	124	7	extending	extend	VBG
cord-009615-xcz8m9a7	124	8	to	to	IN
cord-009615-xcz8m9a7	124	9	an	an	DT
cord-009615-xcz8m9a7	124	10	infected	infected	JJ
cord-009615-xcz8m9a7	124	11	oligodendrocyte	oligodendrocyte	NNP
cord-009615-xcz8m9a7	124	12	(	(	-LRB-
cord-009615-xcz8m9a7	124	13	arrowhead	arrowhead	NNP
cord-009615-xcz8m9a7	124	14	)	)	-RRB-
cord-009615-xcz8m9a7	124	15	.	.	.
cord-009615-xcz8m9a7	125	1	Smaller	small	JJR
cord-009615-xcz8m9a7	125	2	groups	group	NNS
cord-009615-xcz8m9a7	125	3	of	of	IN
cord-009615-xcz8m9a7	125	4	,	,	,
cord-009615-xcz8m9a7	125	5	infected	infected	JJ
cord-009615-xcz8m9a7	125	6	oligodendrocytes	oligodendrocyte	NNS
cord-009615-xcz8m9a7	125	7	were	be	VBD
cord-009615-xcz8m9a7	125	8	seen	see	VBN
cord-009615-xcz8m9a7	125	9	at	at	IN
cord-009615-xcz8m9a7	125	10	this	this	DT
cord-009615-xcz8m9a7	125	11	location	location	NN
cord-009615-xcz8m9a7	125	12	in	in	IN
cord-009615-xcz8m9a7	125	13	both	both	DT
cord-009615-xcz8m9a7	125	14	adjacent	adjacent	JJ
cord-009615-xcz8m9a7	125	15	sections	section	NNS
cord-009615-xcz8m9a7	125	16	indicating	indicate	VBG
cord-009615-xcz8m9a7	125	17	that	that	IN
cord-009615-xcz8m9a7	125	18	the	the	DT
cord-009615-xcz8m9a7	125	19	infected	infected	JJ
cord-009615-xcz8m9a7	125	20	cells	cell	NNS
cord-009615-xcz8m9a7	125	21	surround	surround	VBP
cord-009615-xcz8m9a7	125	22	the	the	DT
cord-009615-xcz8m9a7	125	23	astrocyte	astrocyte	NN
cord-009615-xcz8m9a7	125	24	on	on	IN
cord-009615-xcz8m9a7	125	25	all	all	DT
cord-009615-xcz8m9a7	125	26	sides	side	NNS
cord-009615-xcz8m9a7	125	27	.	.	.
cord-009615-xcz8m9a7	126	1	x	x	SYM
cord-009615-xcz8m9a7	126	2	350	350	CD
cord-009615-xcz8m9a7	126	3	;	;	:
cord-009615-xcz8m9a7	127	1	b	b	LS
cord-009615-xcz8m9a7	127	2	A	a	DT
cord-009615-xcz8m9a7	127	3	similar	similar	JJ
cord-009615-xcz8m9a7	127	4	cluster	cluster	NN
cord-009615-xcz8m9a7	127	5	in	in	IN
cord-009615-xcz8m9a7	127	6	another	another	DT
cord-009615-xcz8m9a7	127	7	section	section	NN
cord-009615-xcz8m9a7	127	8	.	.	.
cord-009615-xcz8m9a7	128	1	lmmunostaining	lmmunostaine	VBG
cord-009615-xcz8m9a7	128	2	by	by	IN
cord-009615-xcz8m9a7	128	3	monoclonal	monoclonal	JJ
cord-009615-xcz8m9a7	128	4	antibodies	antibody	NNS
cord-009615-xcz8m9a7	128	5	BH3	bh3	NN
cord-009615-xcz8m9a7	128	6	and	and	CC
cord-009615-xcz8m9a7	128	7	CE5	CE5	VBN
cord-009615-xcz8m9a7	128	8	to	to	IN
cord-009615-xcz8m9a7	128	9	SV40	SV40	NNP
cord-009615-xcz8m9a7	128	10	capsid	capsid	NN
cord-009615-xcz8m9a7	128	11	proteins	protein	NNS
cord-009615-xcz8m9a7	128	12	(	(	-LRB-
cord-009615-xcz8m9a7	128	13	1	1	CD
cord-009615-xcz8m9a7	128	14	26	26	CD
cord-009615-xcz8m9a7	128	15	)	)	-RRB-
cord-009615-xcz8m9a7	128	16	with	with	IN
cord-009615-xcz8m9a7	128	17	biotinylated	biotinylated	NNP
cord-009615-xcz8m9a7	128	18	goat	goat	NNP
cord-009615-xcz8m9a7	128	19	antibody	antibody	NN
cord-009615-xcz8m9a7	128	20	to	to	TO
cord-009615-xcz8m9a7	128	21	mouse	mouse	VB
cord-009615-xcz8m9a7	129	1	IgG.	IgG.	NNP
cord-009615-xcz8m9a7	129	2	followed	follow	VBN
cord-009615-xcz8m9a7	129	3	by	by	IN
cord-009615-xcz8m9a7	129	4	peroxidase	peroxidase	JJ
cord-009615-xcz8m9a7	129	5	conjugated	conjugate	VBN
cord-009615-xcz8m9a7	129	6	streptavidin	streptavidin	NNS
cord-009615-xcz8m9a7	129	7	as	as	IN
cord-009615-xcz8m9a7	129	8	described	describe	VBN
cord-009615-xcz8m9a7	129	9	(	(	-LRB-
cord-009615-xcz8m9a7	129	10	1	1	CD
cord-009615-xcz8m9a7	129	11	27	27	CD
cord-009615-xcz8m9a7	129	12	)	)	-RRB-
cord-009615-xcz8m9a7	129	13	.	.	.
cord-009615-xcz8m9a7	130	1	No	no	DT
cord-009615-xcz8m9a7	130	2	counterstain	counterstain	NN
cord-009615-xcz8m9a7	130	3	.	.	.
cord-009615-xcz8m9a7	131	1	x	x	LS
cord-009615-xcz8m9a7	132	1	175	175	CD
cord-009615-xcz8m9a7	132	2	early	early	JJ
cord-009615-xcz8m9a7	132	3	PML	PML	NNP
cord-009615-xcz8m9a7	132	4	could	could	MD
cord-009615-xcz8m9a7	132	5	result	result	VB
cord-009615-xcz8m9a7	132	6	from	from	IN
cord-009615-xcz8m9a7	132	7	cytolysis	cytolysis	NN
cord-009615-xcz8m9a7	132	8	of	of	IN
cord-009615-xcz8m9a7	132	9	a	a	DT
cord-009615-xcz8m9a7	132	10	cluster	cluster	NN
cord-009615-xcz8m9a7	132	11	of	of	IN
cord-009615-xcz8m9a7	132	12	oligodendrocytes	oligodendrocyte	NNS
cord-009615-xcz8m9a7	132	13	infected	infect	VBN
cord-009615-xcz8m9a7	132	14	by	by	IN
cord-009615-xcz8m9a7	132	15	contact	contact	NN
cord-009615-xcz8m9a7	132	16	with	with	IN
cord-009615-xcz8m9a7	132	17	the	the	DT
cord-009615-xcz8m9a7	132	18	same	same	JJ
cord-009615-xcz8m9a7	132	19	infected	infect	VBN
cord-009615-xcz8m9a7	132	20	astrocyte	astrocyte	NN
cord-009615-xcz8m9a7	132	21	.	.	.
cord-009615-xcz8m9a7	133	1	The	the	DT
cord-009615-xcz8m9a7	133	2	length	length	NN
cord-009615-xcz8m9a7	133	3	of	of	IN
cord-009615-xcz8m9a7	133	4	the	the	DT
cord-009615-xcz8m9a7	133	5	processes	process	NNS
cord-009615-xcz8m9a7	133	6	of	of	IN
cord-009615-xcz8m9a7	133	7	this	this	DT
cord-009615-xcz8m9a7	133	8	central	central	JJ
cord-009615-xcz8m9a7	133	9	astrocyte	astrocyte	NN
cord-009615-xcz8m9a7	133	10	would	would	MD
cord-009615-xcz8m9a7	133	11	determine	determine	VB
cord-009615-xcz8m9a7	133	12	the	the	DT
cord-009615-xcz8m9a7	133	13	diameter	diameter	NN
cord-009615-xcz8m9a7	133	14	of	of	IN
cord-009615-xcz8m9a7	133	15	this	this	DT
cord-009615-xcz8m9a7	133	16	early	early	JJ
cord-009615-xcz8m9a7	133	17	focus	focus	NN
cord-009615-xcz8m9a7	133	18	of	of	IN
cord-009615-xcz8m9a7	133	19	infection	infection	NN
cord-009615-xcz8m9a7	133	20	,	,	,
cord-009615-xcz8m9a7	133	21	and	and	CC
cord-009615-xcz8m9a7	133	22	thus	thus	RB
cord-009615-xcz8m9a7	133	23	the	the	DT
cord-009615-xcz8m9a7	133	24	extent	extent	NN
cord-009615-xcz8m9a7	133	25	of	of	IN
cord-009615-xcz8m9a7	133	26	the	the	DT
cord-009615-xcz8m9a7	133	27	lesion	lesion	NN
cord-009615-xcz8m9a7	133	28	(	(	-LRB-
cord-009615-xcz8m9a7	133	29	0.1	0.1	CD
cord-009615-xcz8m9a7	133	30	to	to	TO
cord-009615-xcz8m9a7	133	31	2.0	2.0	CD
cord-009615-xcz8m9a7	133	32	mm	mm	CD
cord-009615-xcz8m9a7	133	33	)	)	-RRB-
cord-009615-xcz8m9a7	133	34	.	.	.
cord-009615-xcz8m9a7	134	1	The	the	DT
cord-009615-xcz8m9a7	134	2	infected	infected	JJ
cord-009615-xcz8m9a7	134	3	astrocyte	astrocyte	NN
cord-009615-xcz8m9a7	134	4	could	could	MD
cord-009615-xcz8m9a7	134	5	have	have	VB
cord-009615-xcz8m9a7	134	6	received	receive	VBN
cord-009615-xcz8m9a7	134	7	its	-PRON-	PRP$
cord-009615-xcz8m9a7	134	8	virus	virus	NN
cord-009615-xcz8m9a7	134	9	from	from	IN
cord-009615-xcz8m9a7	134	10	an	an	DT
cord-009615-xcz8m9a7	134	11	infected	infected	JJ
cord-009615-xcz8m9a7	134	12	endothelial	endothelial	JJ
cord-009615-xcz8m9a7	134	13	cell	cell	NN
cord-009615-xcz8m9a7	134	14	.	.	.
cord-009615-xcz8m9a7	135	1	Although	although	IN
cord-009615-xcz8m9a7	135	2	endothelial	endothelial	JJ
cord-009615-xcz8m9a7	135	3	cell	cell	NN
cord-009615-xcz8m9a7	135	4	infection	infection	NN
cord-009615-xcz8m9a7	135	5	is	be	VBZ
cord-009615-xcz8m9a7	135	6	well	well	RB
cord-009615-xcz8m9a7	135	7	recognized	recognize	VBN
cord-009615-xcz8m9a7	135	8	as	as	IN
cord-009615-xcz8m9a7	135	9	a	a	DT
cord-009615-xcz8m9a7	135	10	possible	possible	JJ
cord-009615-xcz8m9a7	135	11	route	route	NN
cord-009615-xcz8m9a7	135	12	for	for	IN
cord-009615-xcz8m9a7	135	13	virus	virus	NN
cord-009615-xcz8m9a7	135	14	penetration	penetration	NN
cord-009615-xcz8m9a7	135	15	into	into	IN
cord-009615-xcz8m9a7	135	16	the	the	DT
cord-009615-xcz8m9a7	135	17	brain	brain	NN
cord-009615-xcz8m9a7	135	18	(	(	-LRB-
cord-009615-xcz8m9a7	135	19	136	136	CD
cord-009615-xcz8m9a7	135	20	)	)	-RRB-
cord-009615-xcz8m9a7	135	21	,	,	,
cord-009615-xcz8m9a7	135	22	it	-PRON-	PRP
cord-009615-xcz8m9a7	135	23	must	must	MD
cord-009615-xcz8m9a7	135	24	be	be	VB
cord-009615-xcz8m9a7	135	25	emphasized	emphasize	VBN
cord-009615-xcz8m9a7	135	26	that	that	IN
cord-009615-xcz8m9a7	135	27	direct	direct	JJ
cord-009615-xcz8m9a7	135	28	evidence	evidence	NN
cord-009615-xcz8m9a7	135	29	for	for	IN
cord-009615-xcz8m9a7	135	30	polyomavirus	polyomavirus	NNP
cord-009615-xcz8m9a7	135	31	transfer	transfer	NN
cord-009615-xcz8m9a7	135	32	along	along	IN
cord-009615-xcz8m9a7	135	33	this	this	DT
cord-009615-xcz8m9a7	135	34	pathway	pathway	NN
cord-009615-xcz8m9a7	135	35	is	be	VBZ
cord-009615-xcz8m9a7	135	36	lacking	lack	VBG
cord-009615-xcz8m9a7	135	37	and	and	CC
cord-009615-xcz8m9a7	135	38	at	at	IN
cord-009615-xcz8m9a7	135	39	present	present	JJ
cord-009615-xcz8m9a7	135	40	this	this	DT
cord-009615-xcz8m9a7	135	41	scheme	scheme	NN
cord-009615-xcz8m9a7	135	42	is	be	VBZ
cord-009615-xcz8m9a7	135	43	a	a	DT
cord-009615-xcz8m9a7	135	44	working	work	VBG
cord-009615-xcz8m9a7	135	45	hypothesis	hypothesis	NN
cord-009615-xcz8m9a7	135	46	.	.	.
cord-009615-xcz8m9a7	136	1	Secondly	secondly	RB
cord-009615-xcz8m9a7	136	2	,	,	,
cord-009615-xcz8m9a7	136	3	clusters	cluster	NNS
cord-009615-xcz8m9a7	136	4	of	of	IN
cord-009615-xcz8m9a7	136	5	infected	infected	JJ
cord-009615-xcz8m9a7	136	6	glial	glial	JJ
cord-009615-xcz8m9a7	136	7	cells	cell	NNS
cord-009615-xcz8m9a7	136	8	could	could	MD
cord-009615-xcz8m9a7	136	9	arise	arise	VB
cord-009615-xcz8m9a7	136	10	when	when	WRB
cord-009615-xcz8m9a7	136	11	virus	virus	NN
cord-009615-xcz8m9a7	136	12	is	be	VBZ
cord-009615-xcz8m9a7	136	13	passed	pass	VBN
cord-009615-xcz8m9a7	136	14	to	to	IN
cord-009615-xcz8m9a7	136	15	daughter	daughter	NN
cord-009615-xcz8m9a7	136	16	cells	cell	NNS
cord-009615-xcz8m9a7	136	17	from	from	IN
cord-009615-xcz8m9a7	136	18	a	a	DT
cord-009615-xcz8m9a7	136	19	common	common	JJ
cord-009615-xcz8m9a7	136	20	infected	infected	JJ
cord-009615-xcz8m9a7	136	21	glial	glial	JJ
cord-009615-xcz8m9a7	136	22	precursor	precursor	NN
cord-009615-xcz8m9a7	136	23	during	during	IN
cord-009615-xcz8m9a7	136	24	cell	cell	NN
cord-009615-xcz8m9a7	136	25	proliferation	proliferation	NN
cord-009615-xcz8m9a7	136	26	.	.	.
cord-009615-xcz8m9a7	137	1	This	this	DT
cord-009615-xcz8m9a7	137	2	could	could	MD
cord-009615-xcz8m9a7	137	3	OCN	OCN	NNP
cord-009615-xcz8m9a7	137	4	with	with	IN
cord-009615-xcz8m9a7	137	5	free	free	JJ
cord-009615-xcz8m9a7	137	6	or	or	CC
cord-009615-xcz8m9a7	137	7	integrated	integrated	JJ
cord-009615-xcz8m9a7	137	8	virus	virus	NN
cord-009615-xcz8m9a7	137	9	.	.	.
cord-009615-xcz8m9a7	138	1	The	the	DT
cord-009615-xcz8m9a7	138	2	size	size	NN
cord-009615-xcz8m9a7	138	3	of	of	IN
cord-009615-xcz8m9a7	138	4	such	such	JJ
cord-009615-xcz8m9a7	138	5	clusters	cluster	NNS
cord-009615-xcz8m9a7	138	6	would	would	MD
cord-009615-xcz8m9a7	138	7	be	be	VB
cord-009615-xcz8m9a7	138	8	determined	determine	VBN
cord-009615-xcz8m9a7	138	9	by	by	IN
cord-009615-xcz8m9a7	138	10	the	the	DT
cord-009615-xcz8m9a7	138	11	stage	stage	NN
cord-009615-xcz8m9a7	138	12	of	of	IN
cord-009615-xcz8m9a7	138	13	development	development	NN
cord-009615-xcz8m9a7	138	14	at	at	IN
cord-009615-xcz8m9a7	138	15	which	which	WDT
cord-009615-xcz8m9a7	138	16	infection	infection	NN
cord-009615-xcz8m9a7	138	17	initially	initially	RB
cord-009615-xcz8m9a7	138	18	occurs	occur	VBZ
cord-009615-xcz8m9a7	138	19	and	and	CC
cord-009615-xcz8m9a7	138	20	the	the	DT
cord-009615-xcz8m9a7	138	21	efficiency	efficiency	NN
cord-009615-xcz8m9a7	138	22	with	with	IN
cord-009615-xcz8m9a7	138	23	which	which	WDT
cord-009615-xcz8m9a7	138	24	the	the	DT
cord-009615-xcz8m9a7	138	25	viral	viral	JJ
cord-009615-xcz8m9a7	138	26	minichromosome	minichromosome	NN
cord-009615-xcz8m9a7	138	27	persists	persist	VBZ
cord-009615-xcz8m9a7	138	28	and	and	CC
cord-009615-xcz8m9a7	138	29	replicates	replicate	VBZ
cord-009615-xcz8m9a7	138	30	.	.	.
cord-009615-xcz8m9a7	139	1	Thirdly	thirdly	RB
cord-009615-xcz8m9a7	139	2	,	,	,
cord-009615-xcz8m9a7	139	3	a	a	DT
cord-009615-xcz8m9a7	139	4	cluster	cluster	NN
cord-009615-xcz8m9a7	139	5	of	of	IN
cord-009615-xcz8m9a7	139	6	infected	infected	JJ
cord-009615-xcz8m9a7	139	7	cells	cell	NNS
cord-009615-xcz8m9a7	139	8	might	may	MD
cord-009615-xcz8m9a7	139	9	arise	arise	VB
cord-009615-xcz8m9a7	139	10	by	by	IN
cord-009615-xcz8m9a7	139	11	infection	infection	NN
cord-009615-xcz8m9a7	139	12	with	with	IN
cord-009615-xcz8m9a7	139	13	extracellular	extracellular	JJ
cord-009615-xcz8m9a7	139	14	virus	virus	NN
cord-009615-xcz8m9a7	139	15	released	release	VBN
cord-009615-xcz8m9a7	139	16	from	from	IN
cord-009615-xcz8m9a7	139	17	a	a	DT
cord-009615-xcz8m9a7	139	18	lysed	lyse	VBN
cord-009615-xcz8m9a7	139	19	cell	cell	NN
cord-009615-xcz8m9a7	139	20	and	and	CC
cord-009615-xcz8m9a7	139	21	diffused	diffuse	VBN
cord-009615-xcz8m9a7	139	22	locally	locally	RB
cord-009615-xcz8m9a7	139	23	.	.	.
cord-009615-xcz8m9a7	140	1	This	this	DT
cord-009615-xcz8m9a7	140	2	latter	latter	JJ
cord-009615-xcz8m9a7	140	3	possibility	possibility	NN
cord-009615-xcz8m9a7	140	4	seems	seem	VBZ
cord-009615-xcz8m9a7	140	5	less	less	RBR
cord-009615-xcz8m9a7	140	6	likely	likely	JJ
cord-009615-xcz8m9a7	140	7	,	,	,
cord-009615-xcz8m9a7	140	8	as	as	IN
cord-009615-xcz8m9a7	140	9	it	-PRON-	PRP
cord-009615-xcz8m9a7	140	10	should	should	MD
cord-009615-xcz8m9a7	140	11	be	be	VB
cord-009615-xcz8m9a7	140	12	a	a	DT
cord-009615-xcz8m9a7	140	13	recurring	recurring	JJ
cord-009615-xcz8m9a7	140	14	feature	feature	NN
cord-009615-xcz8m9a7	140	15	of	of	IN
cord-009615-xcz8m9a7	140	16	spread	spread	NN
cord-009615-xcz8m9a7	140	17	beyond	beyond	IN
cord-009615-xcz8m9a7	140	18	coalescing	coalesce	VBG
cord-009615-xcz8m9a7	140	19	lesions	lesion	NNS
cord-009615-xcz8m9a7	140	20	within	within	IN
cord-009615-xcz8m9a7	140	21	the	the	DT
cord-009615-xcz8m9a7	140	22	brain	brain	NN
cord-009615-xcz8m9a7	140	23	,	,	,
cord-009615-xcz8m9a7	140	24	not	not	RB
cord-009615-xcz8m9a7	140	25	a	a	DT
cord-009615-xcz8m9a7	140	26	feature	feature	NN
cord-009615-xcz8m9a7	140	27	limited	limit	VBN
cord-009615-xcz8m9a7	140	28	to	to	IN
cord-009615-xcz8m9a7	140	29	very	very	RB
cord-009615-xcz8m9a7	140	30	early	early	JJ
cord-009615-xcz8m9a7	140	31	lesions	lesion	NNS
cord-009615-xcz8m9a7	140	32	and	and	CC
cord-009615-xcz8m9a7	140	33	very	very	RB
cord-009615-xcz8m9a7	140	34	early	early	JJ
cord-009615-xcz8m9a7	140	35	disease	disease	NN
cord-009615-xcz8m9a7	140	36	.	.	.
cord-009615-xcz8m9a7	141	1	Environmental	environmental	JJ
cord-009615-xcz8m9a7	141	2	factors	factor	NNS
cord-009615-xcz8m9a7	141	3	will	will	MD
cord-009615-xcz8m9a7	141	4	modulate	modulate	VB
cord-009615-xcz8m9a7	141	5	the	the	DT
cord-009615-xcz8m9a7	141	6	viral	viral	JJ
cord-009615-xcz8m9a7	141	7	and	and	CC
cord-009615-xcz8m9a7	141	8	host	host	NN
cord-009615-xcz8m9a7	141	9	genetic	genetic	JJ
cord-009615-xcz8m9a7	141	10	determinants	determinant	NNS
cord-009615-xcz8m9a7	141	11	.	.	.
cord-009615-xcz8m9a7	142	1	These	these	DT
cord-009615-xcz8m9a7	142	2	could	could	MD
cord-009615-xcz8m9a7	142	3	include	include	VB
cord-009615-xcz8m9a7	142	4	coinfection	coinfection	NN
cord-009615-xcz8m9a7	142	5	with	with	IN
cord-009615-xcz8m9a7	142	6	closely	closely	RB
cord-009615-xcz8m9a7	142	7	related	relate	VBN
cord-009615-xcz8m9a7	142	8	viruses	virus	NNS
cord-009615-xcz8m9a7	142	9	which	which	WDT
cord-009615-xcz8m9a7	142	10	may	may	MD
cord-009615-xcz8m9a7	142	11	influence	influence	VB
cord-009615-xcz8m9a7	142	12	the	the	DT
cord-009615-xcz8m9a7	142	13	immune	immune	JJ
cord-009615-xcz8m9a7	142	14	response	response	NN
cord-009615-xcz8m9a7	142	15	to	to	IN
cord-009615-xcz8m9a7	142	16	the	the	DT
cord-009615-xcz8m9a7	142	17	pathogenic	pathogenic	JJ
cord-009615-xcz8m9a7	142	18	virus	virus	NN
cord-009615-xcz8m9a7	142	19	.	.	.
cord-009615-xcz8m9a7	143	1	In	in	IN
cord-009615-xcz8m9a7	143	2	the	the	DT
cord-009615-xcz8m9a7	143	3	case	case	NN
cord-009615-xcz8m9a7	143	4	of	of	IN
cord-009615-xcz8m9a7	143	5	JCV	JCV	NNP
cord-009615-xcz8m9a7	143	6	,	,	,
cord-009615-xcz8m9a7	143	7	these	these	DT
cord-009615-xcz8m9a7	143	8	would	would	MD
cord-009615-xcz8m9a7	143	9	include	include	VB
cord-009615-xcz8m9a7	143	10	various	various	JJ
cord-009615-xcz8m9a7	143	11	serotypes	serotype	NNS
cord-009615-xcz8m9a7	143	12	of	of	IN
cord-009615-xcz8m9a7	143	13	BKV	BKV	NNP
cord-009615-xcz8m9a7	143	14	(	(	-LRB-
cord-009615-xcz8m9a7	143	15	137	137	CD
cord-009615-xcz8m9a7	143	16	,	,	,
cord-009615-xcz8m9a7	143	17	138	138	CD
cord-009615-xcz8m9a7	143	18	)	)	-RRB-
cord-009615-xcz8m9a7	143	19	.	.	.
cord-009615-xcz8m9a7	144	1	The	the	DT
cord-009615-xcz8m9a7	144	2	existence	existence	NN
cord-009615-xcz8m9a7	144	3	of	of	IN
cord-009615-xcz8m9a7	144	4	distinct	distinct	JJ
cord-009615-xcz8m9a7	144	5	serotypes	serotype	NNS
cord-009615-xcz8m9a7	144	6	of	of	IN
cord-009615-xcz8m9a7	144	7	BK	BK	NNP
cord-009615-xcz8m9a7	144	8	virus	virus	NN
cord-009615-xcz8m9a7	144	9	has	have	VBZ
cord-009615-xcz8m9a7	144	10	been	be	VBN
cord-009615-xcz8m9a7	144	11	confirmed	confirm	VBN
cord-009615-xcz8m9a7	144	12	by	by	IN
cord-009615-xcz8m9a7	144	13	DNA	dna	NN
cord-009615-xcz8m9a7	144	14	sequence	sequence	NN
cord-009615-xcz8m9a7	144	15	comparison	comparison	NN
cord-009615-xcz8m9a7	144	16	of	of	IN
cord-009615-xcz8m9a7	144	17	wildtype	wildtype	JJ
cord-009615-xcz8m9a7	144	18	BKV(Dun	BKV(Dun	NNP
cord-009615-xcz8m9a7	144	19	)	)	-RRB-
cord-009615-xcz8m9a7	144	20	and	and	CC
cord-009615-xcz8m9a7	144	21	the	the	DT
cord-009615-xcz8m9a7	144	22	variant	variant	NN
cord-009615-xcz8m9a7	144	23	known	know	VBN
cord-009615-xcz8m9a7	144	24	as	as	IN
cord-009615-xcz8m9a7	144	25	BKV(AS	bkv(as	CD
cord-009615-xcz8m9a7	144	26	)	)	-RRB-
cord-009615-xcz8m9a7	144	27	(	(	-LRB-
cord-009615-xcz8m9a7	144	28	139	139	CD
cord-009615-xcz8m9a7	144	29	)	)	-RRB-
cord-009615-xcz8m9a7	144	30	.	.	.
cord-009615-xcz8m9a7	145	1	BKV	BKV	NNP
cord-009615-xcz8m9a7	145	2	infection	infection	NN
cord-009615-xcz8m9a7	145	3	will	will	MD
cord-009615-xcz8m9a7	145	4	probably	probably	RB
cord-009615-xcz8m9a7	145	5	modulate	modulate	VB
cord-009615-xcz8m9a7	145	6	the	the	DT
cord-009615-xcz8m9a7	145	7	immune	immune	JJ
cord-009615-xcz8m9a7	145	8	response	response	NN
cord-009615-xcz8m9a7	145	9	to	to	IN
cord-009615-xcz8m9a7	145	10	the	the	DT
cord-009615-xcz8m9a7	145	11	potentially	potentially	RB
cord-009615-xcz8m9a7	145	12	cross	cross	JJ
cord-009615-xcz8m9a7	145	13	-	-	JJ
cord-009615-xcz8m9a7	145	14	reactive	reactive	JJ
cord-009615-xcz8m9a7	145	15	JCV	JCV	NNP
cord-009615-xcz8m9a7	145	16	(=	(=	NNP
cord-009615-xcz8m9a7	145	17	80	80	CD
cord-009615-xcz8m9a7	145	18	%	%	NN
cord-009615-xcz8m9a7	145	19	amino	amino	NN
cord-009615-xcz8m9a7	145	20	acid	acid	NN
cord-009615-xcz8m9a7	145	21	sequence	sequence	NN
cord-009615-xcz8m9a7	145	22	identity	identity	NN
cord-009615-xcz8m9a7	145	23	(	(	-LRB-
cord-009615-xcz8m9a7	145	24	79	79	CD
cord-009615-xcz8m9a7	145	25	)	)	-RRB-
cord-009615-xcz8m9a7	145	26	)	)	-RRB-
cord-009615-xcz8m9a7	145	27	.	.	.
cord-009615-xcz8m9a7	146	1	The	the	DT
cord-009615-xcz8m9a7	146	2	BKV(AS	bkv(as	CD
cord-009615-xcz8m9a7	146	3	)	)	-RRB-
cord-009615-xcz8m9a7	146	4	strains	strain	NNS
cord-009615-xcz8m9a7	146	5	,	,	,
cord-009615-xcz8m9a7	146	6	which	which	WDT
cord-009615-xcz8m9a7	146	7	comprised	comprise	VBD
cord-009615-xcz8m9a7	146	8	15	15	CD
cord-009615-xcz8m9a7	146	9	%	%	NN
cord-009615-xcz8m9a7	146	10	of	of	IN
cord-009615-xcz8m9a7	146	11	BKV	BKV	NNP
cord-009615-xcz8m9a7	146	12	strains	strain	NNS
cord-009615-xcz8m9a7	146	13	in	in	IN
cord-009615-xcz8m9a7	146	14	one	one	CD
cord-009615-xcz8m9a7	146	15	series	series	NN
cord-009615-xcz8m9a7	146	16	of	of	IN
cord-009615-xcz8m9a7	146	17	urinary	urinary	JJ
cord-009615-xcz8m9a7	146	18	isolates	isolate	NNS
cord-009615-xcz8m9a7	146	19	(	(	-LRB-
cord-009615-xcz8m9a7	146	20	140	140	CD
cord-009615-xcz8m9a7	146	21	)	)	-RRB-
cord-009615-xcz8m9a7	146	22	,	,	,
cord-009615-xcz8m9a7	146	23	lack	lack	VBP
cord-009615-xcz8m9a7	146	24	the	the	DT
cord-009615-xcz8m9a7	146	25	primary	primary	JJ
cord-009615-xcz8m9a7	146	26	antigenic	antigenic	JJ
cord-009615-xcz8m9a7	146	27	epitope	epitope	NN
cord-009615-xcz8m9a7	146	28	on	on	IN
cord-009615-xcz8m9a7	146	29	the	the	DT
cord-009615-xcz8m9a7	146	30	wild	wild	JJ
cord-009615-xcz8m9a7	146	31	type	type	NN
cord-009615-xcz8m9a7	146	32	BKV	BKV	NNP
cord-009615-xcz8m9a7	146	33	capsid	capsid	NN
cord-009615-xcz8m9a7	146	34	(	(	-LRB-
cord-009615-xcz8m9a7	146	35	139	139	CD
cord-009615-xcz8m9a7	146	36	)	)	-RRB-
cord-009615-xcz8m9a7	146	37	,	,	,
cord-009615-xcz8m9a7	146	38	as	as	IN
cord-009615-xcz8m9a7	146	39	do	do	VB
cord-009615-xcz8m9a7	146	40	the	the	DT
cord-009615-xcz8m9a7	146	41	BKV(DB	bkv(db	CD
cord-009615-xcz8m9a7	146	42	)	)	-RRB-
cord-009615-xcz8m9a7	146	43	strains	strain	NNS
cord-009615-xcz8m9a7	146	44	(	(	-LRB-
cord-009615-xcz8m9a7	146	45	138	138	CD
cord-009615-xcz8m9a7	146	46	)	)	-RRB-
cord-009615-xcz8m9a7	146	47	.	.	.
cord-009615-xcz8m9a7	147	1	Which	which	WDT
cord-009615-xcz8m9a7	147	2	one	one	CD
cord-009615-xcz8m9a7	147	3	of	of	IN
cord-009615-xcz8m9a7	147	4	these	these	DT
cord-009615-xcz8m9a7	147	5	potentially	potentially	RB
cord-009615-xcz8m9a7	147	6	cross	cross	JJ
cord-009615-xcz8m9a7	147	7	-	-	JJ
cord-009615-xcz8m9a7	147	8	reactive	reactive	JJ
cord-009615-xcz8m9a7	147	9	BKV	BKV	NNP
cord-009615-xcz8m9a7	147	10	serotypes	serotype	NNS
cord-009615-xcz8m9a7	147	11	is	be	VBZ
cord-009615-xcz8m9a7	147	12	associated	associate	VBN
cord-009615-xcz8m9a7	147	13	with	with	IN
cord-009615-xcz8m9a7	147	14	a	a	DT
cord-009615-xcz8m9a7	147	15	JCV	JCV	NNP
cord-009615-xcz8m9a7	147	16	infection	infection	NN
cord-009615-xcz8m9a7	147	17	,	,	,
cord-009615-xcz8m9a7	147	18	and	and	CC
cord-009615-xcz8m9a7	147	19	the	the	DT
cord-009615-xcz8m9a7	147	20	order	order	NN
cord-009615-xcz8m9a7	147	21	in	in	IN
cord-009615-xcz8m9a7	147	22	which	which	WDT
cord-009615-xcz8m9a7	147	23	the	the	DT
cord-009615-xcz8m9a7	147	24	two	two	CD
cord-009615-xcz8m9a7	147	25	infections	infection	NNS
cord-009615-xcz8m9a7	147	26	were	be	VBD
cord-009615-xcz8m9a7	147	27	acquired	acquire	VBN
cord-009615-xcz8m9a7	147	28	,	,	,
cord-009615-xcz8m9a7	147	29	might	may	MD
cord-009615-xcz8m9a7	147	30	significantly	significantly	RB
cord-009615-xcz8m9a7	147	31	influence	influence	VB
cord-009615-xcz8m9a7	147	32	JCV	JCV	NNP
cord-009615-xcz8m9a7	147	33	immunoregulation	immunoregulation	NN
cord-009615-xcz8m9a7	147	34	.	.	.
cord-009615-xcz8m9a7	148	1	In	in	IN
cord-009615-xcz8m9a7	148	2	general	general	JJ
cord-009615-xcz8m9a7	148	3	,	,	,
cord-009615-xcz8m9a7	148	4	antibodies	antibody	NNS
cord-009615-xcz8m9a7	148	5	to	to	IN
cord-009615-xcz8m9a7	148	6	BKV	BKV	NNP
cord-009615-xcz8m9a7	148	7	are	be	VBP
cord-009615-xcz8m9a7	148	8	acquired	acquire	VBN
cord-009615-xcz8m9a7	148	9	by	by	IN
cord-009615-xcz8m9a7	148	10	the	the	DT
cord-009615-xcz8m9a7	148	11	population	population	NN
cord-009615-xcz8m9a7	148	12	at	at	IN
cord-009615-xcz8m9a7	148	13	a	a	DT
cord-009615-xcz8m9a7	148	14	younger	young	JJR
cord-009615-xcz8m9a7	148	15	age	age	NN
cord-009615-xcz8m9a7	148	16	than	than	IN
cord-009615-xcz8m9a7	148	17	are	be	VBP
cord-009615-xcz8m9a7	148	18	those	those	DT
cord-009615-xcz8m9a7	148	19	to	to	IN
cord-009615-xcz8m9a7	148	20	JCV	JCV	NNP
cord-009615-xcz8m9a7	148	21	(	(	-LRB-
cord-009615-xcz8m9a7	148	22	48	48	CD
cord-009615-xcz8m9a7	148	23	)	)	-RRB-
cord-009615-xcz8m9a7	148	24	.	.	.
cord-009615-xcz8m9a7	149	1	Reversal	reversal	NN
cord-009615-xcz8m9a7	149	2	of	of	IN
cord-009615-xcz8m9a7	149	3	the	the	DT
cord-009615-xcz8m9a7	149	4	usual	usual	JJ
cord-009615-xcz8m9a7	149	5	order	order	NN
cord-009615-xcz8m9a7	149	6	of	of	IN
cord-009615-xcz8m9a7	149	7	infection	infection	NN
cord-009615-xcz8m9a7	149	8	,	,	,
cord-009615-xcz8m9a7	149	9	i.e.	i.e.	FW
cord-009615-xcz8m9a7	149	10	,	,	,
cord-009615-xcz8m9a7	149	11	acquisition	acquisition	NN
cord-009615-xcz8m9a7	149	12	of	of	IN
cord-009615-xcz8m9a7	149	13	JCV	JCV	NNP
cord-009615-xcz8m9a7	149	14	infection	infection	NN
cord-009615-xcz8m9a7	149	15	before	before	IN
cord-009615-xcz8m9a7	149	16	BKV	BKV	NNP
cord-009615-xcz8m9a7	149	17	,	,	,
cord-009615-xcz8m9a7	149	18	might	may	MD
cord-009615-xcz8m9a7	149	19	influence	influence	VB
cord-009615-xcz8m9a7	149	20	the	the	DT
cord-009615-xcz8m9a7	149	21	strength	strength	NN
cord-009615-xcz8m9a7	149	22	and	and	CC
cord-009615-xcz8m9a7	149	23	specificity	specificity	NN
cord-009615-xcz8m9a7	149	24	of	of	IN
cord-009615-xcz8m9a7	149	25	the	the	DT
cord-009615-xcz8m9a7	149	26	immune	immune	JJ
cord-009615-xcz8m9a7	149	27	response	response	NN
cord-009615-xcz8m9a7	149	28	to	to	IN
cord-009615-xcz8m9a7	149	29	JCV	JCV	NNP
cord-009615-xcz8m9a7	149	30	(	(	-LRB-
cord-009615-xcz8m9a7	149	31	and	and	CC
cord-009615-xcz8m9a7	149	32	BKV	BKV	NNP
cord-009615-xcz8m9a7	149	33	)	)	-RRB-
cord-009615-xcz8m9a7	149	34	.	.	.
cord-009615-xcz8m9a7	150	1	The	the	DT
cord-009615-xcz8m9a7	150	2	cellular	cellular	JJ
cord-009615-xcz8m9a7	150	3	immune	immune	JJ
cord-009615-xcz8m9a7	150	4	responses	response	NNS
cord-009615-xcz8m9a7	150	5	to	to	IN
cord-009615-xcz8m9a7	150	6	JCV	JCV	NNP
cord-009615-xcz8m9a7	150	7	and	and	CC
cord-009615-xcz8m9a7	150	8	BKV	BKV	NNP
cord-009615-xcz8m9a7	150	9	virion	virion	NN
cord-009615-xcz8m9a7	150	10	proteins	protein	NNS
cord-009615-xcz8m9a7	150	11	or	or	CC
cord-009615-xcz8m9a7	150	12	T	t	NN
cord-009615-xcz8m9a7	150	13	-	-	HYPH
cord-009615-xcz8m9a7	150	14	antigens	antigen	NNS
cord-009615-xcz8m9a7	150	15	have	have	VBP
cord-009615-xcz8m9a7	150	16	been	be	VBN
cord-009615-xcz8m9a7	150	17	studied	study	VBN
cord-009615-xcz8m9a7	150	18	very	very	RB
cord-009615-xcz8m9a7	150	19	little	little	JJ
cord-009615-xcz8m9a7	150	20	in	in	IN
cord-009615-xcz8m9a7	150	21	any	any	DT
cord-009615-xcz8m9a7	150	22	human	human	JJ
cord-009615-xcz8m9a7	150	23	populations	population	NNS
cord-009615-xcz8m9a7	150	24	(	(	-LRB-
cord-009615-xcz8m9a7	150	25	141	141	CD
cord-009615-xcz8m9a7	150	26	,	,	,
cord-009615-xcz8m9a7	150	27	142	142	CD
cord-009615-xcz8m9a7	150	28	)	)	-RRB-
cord-009615-xcz8m9a7	150	29	due	due	IN
cord-009615-xcz8m9a7	150	30	to	to	IN
cord-009615-xcz8m9a7	150	31	lack	lack	NN
cord-009615-xcz8m9a7	150	32	of	of	IN
cord-009615-xcz8m9a7	150	33	antigen	antigen	NN
cord-009615-xcz8m9a7	150	34	.	.	.
cord-009615-xcz8m9a7	151	1	The	the	DT
cord-009615-xcz8m9a7	151	2	Role	role	NN
cord-009615-xcz8m9a7	151	3	of	of	IN
cord-009615-xcz8m9a7	151	4	Retroviruses	retrovirus	NNS
cord-009615-xcz8m9a7	151	5	:	:	:
cord-009615-xcz8m9a7	151	6	Late	late	JJ
cord-009615-xcz8m9a7	151	7	Region	Region	NNP
cord-009615-xcz8m9a7	151	8	Transactivution	Transactivution	NNP
cord-009615-xcz8m9a7	151	9	.	.	.
cord-009615-xcz8m9a7	152	1	The	the	DT
cord-009615-xcz8m9a7	152	2	ability	ability	NN
cord-009615-xcz8m9a7	152	3	of	of	IN
cord-009615-xcz8m9a7	152	4	HIV-1	HIV-1	NNP
cord-009615-xcz8m9a7	152	5	Tat	Tat	NNP
cord-009615-xcz8m9a7	152	6	to	to	TO
cord-009615-xcz8m9a7	152	7	transactivate	transactivate	VB
cord-009615-xcz8m9a7	152	8	the	the	DT
cord-009615-xcz8m9a7	152	9	JCV	JCV	NNP
cord-009615-xcz8m9a7	152	10	late	late	JJ
cord-009615-xcz8m9a7	152	11	region	region	NN
cord-009615-xcz8m9a7	152	12	promoter	promoter	NN
cord-009615-xcz8m9a7	152	13	(	(	-LRB-
cord-009615-xcz8m9a7	152	14	90	90	CD
cord-009615-xcz8m9a7	152	15	)	)	-RRB-
cord-009615-xcz8m9a7	152	16	suggests	suggest	VBZ
cord-009615-xcz8m9a7	152	17	that	that	IN
cord-009615-xcz8m9a7	152	18	HIV-1	HIV-1	NNP
cord-009615-xcz8m9a7	152	19	may	may	MD
cord-009615-xcz8m9a7	152	20	play	play	VB
cord-009615-xcz8m9a7	152	21	a	a	DT
cord-009615-xcz8m9a7	152	22	more	more	RBR
cord-009615-xcz8m9a7	152	23	direct	direct	JJ
cord-009615-xcz8m9a7	152	24	role	role	NN
cord-009615-xcz8m9a7	152	25	in	in	IN
cord-009615-xcz8m9a7	152	26	viral	viral	JJ
cord-009615-xcz8m9a7	152	27	reactivation	reactivation	NN
cord-009615-xcz8m9a7	152	28	leading	lead	VBG
cord-009615-xcz8m9a7	152	29	to	to	IN
cord-009615-xcz8m9a7	152	30	the	the	DT
cord-009615-xcz8m9a7	152	31	induction	induction	NN
cord-009615-xcz8m9a7	152	32	of	of	IN
cord-009615-xcz8m9a7	152	33	PML	PML	NNP
cord-009615-xcz8m9a7	152	34	in	in	IN
cord-009615-xcz8m9a7	152	35	AIDS	AIDS	NNP
cord-009615-xcz8m9a7	152	36	than	than	IN
cord-009615-xcz8m9a7	152	37	by	by	IN
cord-009615-xcz8m9a7	152	38	immunosuppression	immunosuppression	NN
cord-009615-xcz8m9a7	152	39	alone	alone	RB
cord-009615-xcz8m9a7	152	40	.	.	.
cord-009615-xcz8m9a7	153	1	In	in	IN
cord-009615-xcz8m9a7	153	2	fact	fact	NN
cord-009615-xcz8m9a7	153	3	,	,	,
cord-009615-xcz8m9a7	153	4	HIV-1	HIV-1	NNP
cord-009615-xcz8m9a7	153	5	Tat	Tat	NNP
cord-009615-xcz8m9a7	153	6	protein	protein	NN
cord-009615-xcz8m9a7	153	7	is	be	VBZ
cord-009615-xcz8m9a7	153	8	a	a	DT
cord-009615-xcz8m9a7	153	9	stronger	strong	JJR
cord-009615-xcz8m9a7	153	10	activator	activator	NN
cord-009615-xcz8m9a7	153	11	of	of	IN
cord-009615-xcz8m9a7	153	12	JCV	JCV	NNP
cord-009615-xcz8m9a7	153	13	late	late	JJ
cord-009615-xcz8m9a7	153	14	region	region	NN
cord-009615-xcz8m9a7	153	15	transcription	transcription	NN
cord-009615-xcz8m9a7	153	16	than	than	IN
cord-009615-xcz8m9a7	153	17	is	be	VBZ
cord-009615-xcz8m9a7	153	18	T	t	NN
cord-009615-xcz8m9a7	153	19	-	-	HYPH
cord-009615-xcz8m9a7	153	20	antigen	antigen	NN
cord-009615-xcz8m9a7	153	21	itself	-PRON-	PRP
cord-009615-xcz8m9a7	153	22	,	,	,
cord-009615-xcz8m9a7	153	23	and	and	CC
cord-009615-xcz8m9a7	153	24	the	the	DT
cord-009615-xcz8m9a7	153	25	two	two	CD
cord-009615-xcz8m9a7	153	26	act	act	NN
cord-009615-xcz8m9a7	153	27	synergistically	synergistically	RB
cord-009615-xcz8m9a7	153	28	(	(	-LRB-
cord-009615-xcz8m9a7	153	29	89	89	CD
cord-009615-xcz8m9a7	153	30	)	)	-RRB-
cord-009615-xcz8m9a7	153	31	.	.	.
cord-009615-xcz8m9a7	154	1	The	the	DT
cord-009615-xcz8m9a7	154	2	potential	potential	JJ
cord-009615-xcz8m9a7	154	3	role	role	NN
cord-009615-xcz8m9a7	154	4	of	of	IN
cord-009615-xcz8m9a7	154	5	HIV-1	HIV-1	NNP
cord-009615-xcz8m9a7	154	6	Tat	Tat	NNP
cord-009615-xcz8m9a7	154	7	in	in	IN
cord-009615-xcz8m9a7	154	8	modulating	modulate	VBG
cord-009615-xcz8m9a7	154	9	JCV	JCV	NNP
cord-009615-xcz8m9a7	154	10	antigen	antigen	NN
cord-009615-xcz8m9a7	154	11	expression	expression	NN
cord-009615-xcz8m9a7	154	12	during	during	IN
cord-009615-xcz8m9a7	154	13	latency	latency	NN
cord-009615-xcz8m9a7	154	14	,	,	,
cord-009615-xcz8m9a7	154	15	i.e.	i.e.	FW
cord-009615-xcz8m9a7	154	16	,	,	,
cord-009615-xcz8m9a7	154	17	prior	prior	RB
cord-009615-xcz8m9a7	154	18	to	to	IN
cord-009615-xcz8m9a7	154	19	DNA	dna	NN
cord-009615-xcz8m9a7	154	20	replication	replication	NN
cord-009615-xcz8m9a7	154	21	and	and	CC
cord-009615-xcz8m9a7	154	22	in	in	IN
cord-009615-xcz8m9a7	154	23	the	the	DT
cord-009615-xcz8m9a7	154	24	absence	absence	NN
cord-009615-xcz8m9a7	154	25	of	of	IN
cord-009615-xcz8m9a7	154	26	capsid	capsid	NN
cord-009615-xcz8m9a7	154	27	protein	protein	NN
cord-009615-xcz8m9a7	154	28	synthesis	synthesis	NN
cord-009615-xcz8m9a7	154	29	,	,	,
cord-009615-xcz8m9a7	154	30	remains	remain	VBZ
cord-009615-xcz8m9a7	154	31	to	to	TO
cord-009615-xcz8m9a7	154	32	be	be	VB
cord-009615-xcz8m9a7	154	33	explored	explore	VBN
cord-009615-xcz8m9a7	154	34	.	.	.
cord-009615-xcz8m9a7	155	1	It	-PRON-	PRP
cord-009615-xcz8m9a7	155	2	is	be	VBZ
cord-009615-xcz8m9a7	155	3	noteworthy	noteworthy	JJ
cord-009615-xcz8m9a7	155	4	that	that	IN
cord-009615-xcz8m9a7	155	5	HIV-1	HIV-1	NNP
cord-009615-xcz8m9a7	155	6	infection	infection	NN
cord-009615-xcz8m9a7	155	7	can	can	MD
cord-009615-xcz8m9a7	155	8	promote	promote	VB
cord-009615-xcz8m9a7	155	9	MS	MS	NNP
cord-009615-xcz8m9a7	155	10	-	-	HYPH
cord-009615-xcz8m9a7	155	11	like	like	JJ
cord-009615-xcz8m9a7	155	12	disease	disease	NN
cord-009615-xcz8m9a7	155	13	prior	prior	RB
cord-009615-xcz8m9a7	155	14	to	to	IN
cord-009615-xcz8m9a7	155	15	or	or	CC
cord-009615-xcz8m9a7	155	16	during	during	IN
cord-009615-xcz8m9a7	155	17	onset	onset	NN
cord-009615-xcz8m9a7	155	18	of	of	IN
cord-009615-xcz8m9a7	155	19	clinical	clinical	JJ
cord-009615-xcz8m9a7	155	20	AIDS	AIDS	NNP
cord-009615-xcz8m9a7	155	21	(	(	-LRB-
cord-009615-xcz8m9a7	155	22	143	143	CD
cord-009615-xcz8m9a7	155	23	)	)	-RRB-
cord-009615-xcz8m9a7	156	1	(	(	-LRB-
cord-009615-xcz8m9a7	156	2	144	144	CD
cord-009615-xcz8m9a7	156	3	)	)	-RRB-
cord-009615-xcz8m9a7	157	1	(	(	-LRB-
cord-009615-xcz8m9a7	157	2	145	145	CD
cord-009615-xcz8m9a7	157	3	)	)	-RRB-
cord-009615-xcz8m9a7	158	1	(	(	-LRB-
cord-009615-xcz8m9a7	158	2	146	146	CD
cord-009615-xcz8m9a7	158	3	)	)	-RRB-
cord-009615-xcz8m9a7	158	4	(	(	-LRB-
cord-009615-xcz8m9a7	158	5	147	147	CD
cord-009615-xcz8m9a7	158	6	)	)	-RRB-
cord-009615-xcz8m9a7	158	7	.	.	.
cord-009615-xcz8m9a7	159	1	This	this	DT
cord-009615-xcz8m9a7	159	2	phenomenon	phenomenon	NN
cord-009615-xcz8m9a7	159	3	might	may	MD
cord-009615-xcz8m9a7	159	4	be	be	VB
cord-009615-xcz8m9a7	159	5	a	a	DT
cord-009615-xcz8m9a7	159	6	direct	direct	JJ
cord-009615-xcz8m9a7	159	7	result	result	NN
cord-009615-xcz8m9a7	159	8	of	of	IN
cord-009615-xcz8m9a7	159	9	HIV-1	HIV-1	NNP
cord-009615-xcz8m9a7	159	10	brain	brain	NN
cord-009615-xcz8m9a7	159	11	infection	infection	NN
cord-009615-xcz8m9a7	159	12	,	,	,
cord-009615-xcz8m9a7	159	13	or	or	CC
cord-009615-xcz8m9a7	159	14	an	an	DT
cord-009615-xcz8m9a7	159	15	indirect	indirect	JJ
cord-009615-xcz8m9a7	159	16	effect	effect	NN
cord-009615-xcz8m9a7	159	17	mediated	mediate	VBN
cord-009615-xcz8m9a7	159	18	by	by	IN
cord-009615-xcz8m9a7	159	19	activation	activation	NN
cord-009615-xcz8m9a7	159	20	of	of	IN
cord-009615-xcz8m9a7	159	21	another	another	DT
cord-009615-xcz8m9a7	159	22	latent	latent	JJ
cord-009615-xcz8m9a7	159	23	virus	virus	NN
cord-009615-xcz8m9a7	159	24	.	.	.
cord-009615-xcz8m9a7	160	1	If	if	IN
cord-009615-xcz8m9a7	160	2	the	the	DT
cord-009615-xcz8m9a7	160	3	latter	latter	JJ
cord-009615-xcz8m9a7	160	4	,	,	,
cord-009615-xcz8m9a7	160	5	these	these	DT
cord-009615-xcz8m9a7	160	6	patients	patient	NNS
cord-009615-xcz8m9a7	160	7	might	may	MD
cord-009615-xcz8m9a7	160	8	represent	represent	VB
cord-009615-xcz8m9a7	160	9	a	a	DT
cord-009615-xcz8m9a7	160	10	group	group	NN
cord-009615-xcz8m9a7	160	11	in	in	IN
cord-009615-xcz8m9a7	160	12	which	which	WDT
cord-009615-xcz8m9a7	160	13	abortive	abortive	JJ
cord-009615-xcz8m9a7	160	14	viral	viral	JJ
cord-009615-xcz8m9a7	160	15	reactivation	reactivation	NN
cord-009615-xcz8m9a7	160	16	is	be	VBZ
cord-009615-xcz8m9a7	160	17	sufficient	sufficient	JJ
cord-009615-xcz8m9a7	160	18	to	to	TO
cord-009615-xcz8m9a7	160	19	cause	cause	VB
cord-009615-xcz8m9a7	160	20	neurological	neurological	JJ
cord-009615-xcz8m9a7	160	21	disease	disease	NN
cord-009615-xcz8m9a7	160	22	,	,	,
cord-009615-xcz8m9a7	160	23	but	but	CC
cord-009615-xcz8m9a7	160	24	stops	stop	VBZ
cord-009615-xcz8m9a7	160	25	short	short	RB
cord-009615-xcz8m9a7	160	26	of	of	IN
cord-009615-xcz8m9a7	160	27	active	active	JJ
cord-009615-xcz8m9a7	160	28	viral	viral	JJ
cord-009615-xcz8m9a7	160	29	replication	replication	NN
cord-009615-xcz8m9a7	160	30	and	and	CC
cord-009615-xcz8m9a7	160	31	fatal	fatal	JJ
cord-009615-xcz8m9a7	160	32	productive	productive	JJ
cord-009615-xcz8m9a7	160	33	CNS	cns	NN
cord-009615-xcz8m9a7	160	34	infection	infection	NN
cord-009615-xcz8m9a7	160	35	.	.	.
cord-009615-xcz8m9a7	161	1	TO	to	IN
cord-009615-xcz8m9a7	161	2	date	date	NN
cord-009615-xcz8m9a7	161	3	only	only	RB
cord-009615-xcz8m9a7	161	4	one	one	CD
cord-009615-xcz8m9a7	161	5	AIDS	AIDS	NNP
cord-009615-xcz8m9a7	161	6	patient	patient	NN
cord-009615-xcz8m9a7	161	7	presenting	present	VBG
cord-009615-xcz8m9a7	161	8	with	with	IN
cord-009615-xcz8m9a7	161	9	MS	MS	NNP
cord-009615-xcz8m9a7	161	10	-	-	HYPH
cord-009615-xcz8m9a7	161	11	like	like	JJ
cord-009615-xcz8m9a7	161	12	symptoms	symptom	NNS
cord-009615-xcz8m9a7	161	13	has	have	VBZ
cord-009615-xcz8m9a7	161	14	been	be	VBN
cord-009615-xcz8m9a7	161	15	reported	report	VBN
cord-009615-xcz8m9a7	161	16	to	to	TO
cord-009615-xcz8m9a7	161	17	have	have	VB
cord-009615-xcz8m9a7	161	18	developed	develop	VBN
cord-009615-xcz8m9a7	161	19	PML	PML	NNP
cord-009615-xcz8m9a7	161	20	(	(	-LRB-
cord-009615-xcz8m9a7	161	21	143	143	CD
cord-009615-xcz8m9a7	161	22	)	)	-RRB-
cord-009615-xcz8m9a7	161	23	.	.	.
cord-009615-xcz8m9a7	162	1	In	in	IN
cord-009615-xcz8m9a7	162	2	another	another	DT
cord-009615-xcz8m9a7	162	3	of	of	IN
cord-009615-xcz8m9a7	162	4	these	these	DT
cord-009615-xcz8m9a7	162	5	patients	patient	NNS
cord-009615-xcz8m9a7	162	6	whose	whose	WP$
cord-009615-xcz8m9a7	162	7	brain	brain	NN
cord-009615-xcz8m9a7	162	8	was	be	VBD
cord-009615-xcz8m9a7	162	9	biopsied	biopsie	VBN
cord-009615-xcz8m9a7	162	10	,	,	,
cord-009615-xcz8m9a7	162	11	JCV	JCV	NNP
cord-009615-xcz8m9a7	162	12	replication	replication	NN
cord-009615-xcz8m9a7	162	13	was	be	VBD
cord-009615-xcz8m9a7	162	14	not	not	RB
cord-009615-xcz8m9a7	162	15	detected	detect	VBN
cord-009615-xcz8m9a7	162	16	by	by	IN
cord-009615-xcz8m9a7	162	17	in	in	IN
cord-009615-xcz8m9a7	162	18	sihi	sihi	JJ
cord-009615-xcz8m9a7	162	19	hybridization	hybridization	NN
cord-009615-xcz8m9a7	162	20	,	,	,
cord-009615-xcz8m9a7	162	21	although	although	IN
cord-009615-xcz8m9a7	162	22	PCR	PCR	NNP
cord-009615-xcz8m9a7	162	23	revealed	reveal	VBD
cord-009615-xcz8m9a7	162	24	that	that	IN
cord-009615-xcz8m9a7	162	25	bone	bone	NN
cord-009615-xcz8m9a7	162	26	marrow	marrow	NN
cord-009615-xcz8m9a7	162	27	and	and	CC
cord-009615-xcz8m9a7	162	28	peripheral	peripheral	JJ
cord-009615-xcz8m9a7	162	29	blood	blood	NN
cord-009615-xcz8m9a7	162	30	lymphocytes	lymphocyte	NNS
cord-009615-xcz8m9a7	162	31	were	be	VBD
cord-009615-xcz8m9a7	162	32	infected	infect	VBN
cord-009615-xcz8m9a7	162	33	by	by	IN
cord-009615-xcz8m9a7	162	34	JCV	JCV	NNP
cord-009615-xcz8m9a7	162	35	(	(	-LRB-
cord-009615-xcz8m9a7	162	36	147	147	CD
cord-009615-xcz8m9a7	162	37	)	)	-RRB-
cord-009615-xcz8m9a7	162	38	.	.	.
cord-009615-xcz8m9a7	163	1	Note	note	VB
cord-009615-xcz8m9a7	163	2	,	,	,
cord-009615-xcz8m9a7	163	3	however	however	RB
cord-009615-xcz8m9a7	163	4	,	,	,
cord-009615-xcz8m9a7	163	5	that	that	IN
cord-009615-xcz8m9a7	163	6	if	if	IN
cord-009615-xcz8m9a7	163	7	it	-PRON-	PRP
cord-009615-xcz8m9a7	163	8	is	be	VBZ
cord-009615-xcz8m9a7	163	9	postulated	postulate	VBN
cord-009615-xcz8m9a7	163	10	that	that	IN
cord-009615-xcz8m9a7	163	11	MS	MS	NNP
cord-009615-xcz8m9a7	163	12	patients	patient	NNS
cord-009615-xcz8m9a7	163	13	show	show	VBP
cord-009615-xcz8m9a7	163	14	a	a	DT
cord-009615-xcz8m9a7	163	15	hyperactive	hyperactive	JJ
cord-009615-xcz8m9a7	163	16	immune	immune	JJ
cord-009615-xcz8m9a7	163	17	response	response	NN
cord-009615-xcz8m9a7	163	18	to	to	IN
cord-009615-xcz8m9a7	163	19	a	a	DT
cord-009615-xcz8m9a7	163	20	latent	latent	JJ
cord-009615-xcz8m9a7	163	21	viral	viral	JJ
cord-009615-xcz8m9a7	163	22	brain	brain	NN
cord-009615-xcz8m9a7	163	23	antigen	antigen	NN
cord-009615-xcz8m9a7	163	24	,	,	,
cord-009615-xcz8m9a7	163	25	then	then	RB
cord-009615-xcz8m9a7	163	26	these	these	DT
cord-009615-xcz8m9a7	163	27	patients	patient	NNS
cord-009615-xcz8m9a7	163	28	may	may	MD
cord-009615-xcz8m9a7	163	29	be	be	VB
cord-009615-xcz8m9a7	163	30	less	less	RBR
cord-009615-xcz8m9a7	163	31	likely	likely	JJ
cord-009615-xcz8m9a7	163	32	to	to	TO
cord-009615-xcz8m9a7	163	33	progress	progress	VB
cord-009615-xcz8m9a7	163	34	to	to	IN
cord-009615-xcz8m9a7	163	35	a	a	DT
cord-009615-xcz8m9a7	163	36	productive	productive	JJ
cord-009615-xcz8m9a7	163	37	viral	viral	JJ
cord-009615-xcz8m9a7	163	38	infection	infection	NN
cord-009615-xcz8m9a7	163	39	of	of	IN
cord-009615-xcz8m9a7	163	40	the	the	DT
cord-009615-xcz8m9a7	163	41	brain	brain	NN
cord-009615-xcz8m9a7	163	42	than	than	IN
cord-009615-xcz8m9a7	163	43	those	those	DT
cord-009615-xcz8m9a7	163	44	who	who	WP
cord-009615-xcz8m9a7	163	45	lack	lack	VBP
cord-009615-xcz8m9a7	163	46	an	an	DT
cord-009615-xcz8m9a7	163	47	antiviral	antiviral	JJ
cord-009615-xcz8m9a7	163	48	CNS	CNS	NNP
cord-009615-xcz8m9a7	163	49	immune	immune	JJ
cord-009615-xcz8m9a7	163	50	response	response	NN
cord-009615-xcz8m9a7	163	51	.	.	.
cord-009615-xcz8m9a7	164	1	Thus	thus	RB
cord-009615-xcz8m9a7	164	2	,	,	,
cord-009615-xcz8m9a7	164	3	in	in	IN
cord-009615-xcz8m9a7	164	4	any	any	DT
cord-009615-xcz8m9a7	164	5	cases	case	NNS
cord-009615-xcz8m9a7	164	6	of	of	IN
cord-009615-xcz8m9a7	164	7	MS	MS	NNP
cord-009615-xcz8m9a7	164	8	-	-	HYPH
cord-009615-xcz8m9a7	164	9	like	like	JJ
cord-009615-xcz8m9a7	164	10	demyelinating	demyelinating	JJ
cord-009615-xcz8m9a7	164	11	disease	disease	NN
cord-009615-xcz8m9a7	164	12	in	in	IN
cord-009615-xcz8m9a7	164	13	which	which	WDT
cord-009615-xcz8m9a7	164	14	JCV	JCV	NNP
cord-009615-xcz8m9a7	164	15	provides	provide	VBZ
cord-009615-xcz8m9a7	164	16	the	the	DT
cord-009615-xcz8m9a7	164	17	antigenic	antigenic	JJ
cord-009615-xcz8m9a7	164	18	target	target	NN
cord-009615-xcz8m9a7	164	19	,	,	,
cord-009615-xcz8m9a7	164	20	progres	progres	NN
cord-009615-xcz8m9a7	164	21	-	-	HYPH
cord-009615-xcz8m9a7	164	22	sion	sion	NN
cord-009615-xcz8m9a7	164	23	to	to	IN
cord-009615-xcz8m9a7	164	24	PML	PML	NNP
cord-009615-xcz8m9a7	164	25	under	under	IN
cord-009615-xcz8m9a7	164	26	the	the	DT
cord-009615-xcz8m9a7	164	27	influence	influence	NN
cord-009615-xcz8m9a7	164	28	of	of	IN
cord-009615-xcz8m9a7	164	29	HIV-1	HIV-1	NNP
cord-009615-xcz8m9a7	164	30	infection	infection	NN
cord-009615-xcz8m9a7	164	31	may	may	MD
cord-009615-xcz8m9a7	164	32	actually	actually	RB
cord-009615-xcz8m9a7	164	33	be	be	VB
cord-009615-xcz8m9a7	164	34	less	less	RBR
cord-009615-xcz8m9a7	164	35	likely	likely	JJ
cord-009615-xcz8m9a7	164	36	than	than	IN
cord-009615-xcz8m9a7	164	37	it	-PRON-	PRP
cord-009615-xcz8m9a7	164	38	would	would	MD
cord-009615-xcz8m9a7	164	39	in	in	IN
cord-009615-xcz8m9a7	164	40	ordinary	ordinary	JJ
cord-009615-xcz8m9a7	164	41	JCV	JCV	NNP
cord-009615-xcz8m9a7	164	42	latency	latency	NN
cord-009615-xcz8m9a7	164	43	.	.	.
cord-009615-xcz8m9a7	165	1	A	a	DT
cord-009615-xcz8m9a7	165	2	useful	useful	JJ
cord-009615-xcz8m9a7	165	3	and	and	CC
cord-009615-xcz8m9a7	165	4	instructive	instructive	JJ
cord-009615-xcz8m9a7	165	5	animal	animal	NN
cord-009615-xcz8m9a7	165	6	model	model	NN
cord-009615-xcz8m9a7	165	7	for	for	IN
cord-009615-xcz8m9a7	165	8	immunemediated	immunemediated	JJ
cord-009615-xcz8m9a7	165	9	demyelination	demyelination	NN
cord-009615-xcz8m9a7	165	10	triggered	trigger	VBN
cord-009615-xcz8m9a7	165	11	by	by	IN
cord-009615-xcz8m9a7	165	12	viral	viral	JJ
cord-009615-xcz8m9a7	165	13	antigen	antigen	NN
cord-009615-xcz8m9a7	165	14	in	in	IN
cord-009615-xcz8m9a7	165	15	the	the	DT
cord-009615-xcz8m9a7	165	16	CNS	CNS	NNP
cord-009615-xcz8m9a7	165	17	has	have	VBZ
cord-009615-xcz8m9a7	165	18	been	be	VBN
cord-009615-xcz8m9a7	165	19	provided	provide	VBN
cord-009615-xcz8m9a7	165	20	by	by	IN
cord-009615-xcz8m9a7	165	21	the	the	DT
cord-009615-xcz8m9a7	165	22	Theiler	Theiler	NNP
cord-009615-xcz8m9a7	165	23	's	's	POS
cord-009615-xcz8m9a7	165	24	murine	murine	JJ
cord-009615-xcz8m9a7	165	25	encephalomyelitis	encephalomyelitis	NN
cord-009615-xcz8m9a7	165	26	virus	virus	NN
cord-009615-xcz8m9a7	165	27	infection	infection	NN
cord-009615-xcz8m9a7	165	28	(	(	-LRB-
cord-009615-xcz8m9a7	165	29	34,148	34,148	CD
cord-009615-xcz8m9a7	165	30	)	)	-RRB-
cord-009615-xcz8m9a7	165	31	.	.	.
cord-009615-xcz8m9a7	166	1	Another	another	DT
cord-009615-xcz8m9a7	166	2	w	w	NN
cord-009615-xcz8m9a7	166	3	ell	ell	NNP
cord-009615-xcz8m9a7	166	4	-	-	HYPH
cord-009615-xcz8m9a7	166	5	developed	develop	VBN
cord-009615-xcz8m9a7	166	6	model	model	NN
cord-009615-xcz8m9a7	166	7	is	be	VBZ
cord-009615-xcz8m9a7	166	8	provided	provide	VBN
cord-009615-xcz8m9a7	166	9	by	by	IN
cord-009615-xcz8m9a7	166	10	coronavirusinduced	coronavirusinduced	JJ
cord-009615-xcz8m9a7	166	11	demyelinating	demyelinating	JJ
cord-009615-xcz8m9a7	166	12	encephalomyelitis	encephalomyelitis	NN
cord-009615-xcz8m9a7	166	13	in	in	IN
cord-009615-xcz8m9a7	166	14	rats	rat	NNS
cord-009615-xcz8m9a7	166	15	(	(	-LRB-
cord-009615-xcz8m9a7	166	16	35	35	CD
cord-009615-xcz8m9a7	166	17	-	-	SYM
cord-009615-xcz8m9a7	166	18	37	37	CD
cord-009615-xcz8m9a7	166	19	)	)	-RRB-
cord-009615-xcz8m9a7	166	20	.	.	.
cord-009615-xcz8m9a7	167	1	For	for	IN
cord-009615-xcz8m9a7	167	2	study	study	NN
cord-009615-xcz8m9a7	167	3	of	of	IN
cord-009615-xcz8m9a7	167	4	the	the	DT
cord-009615-xcz8m9a7	167	5	pathogenesis	pathogenesis	NN
cord-009615-xcz8m9a7	167	6	of	of	IN
cord-009615-xcz8m9a7	167	7	polyomaviruses	polyomaviruse	NNS
cord-009615-xcz8m9a7	167	8	in	in	IN
cord-009615-xcz8m9a7	167	9	the	the	DT
cord-009615-xcz8m9a7	167	10	CNS	CNS	NNP
cord-009615-xcz8m9a7	167	11	and	and	CC
cord-009615-xcz8m9a7	167	12	the	the	DT
cord-009615-xcz8m9a7	167	13	potential	potential	JJ
cord-009615-xcz8m9a7	167	14	role	role	NN
cord-009615-xcz8m9a7	167	15	of	of	IN
cord-009615-xcz8m9a7	167	16	these	these	DT
cord-009615-xcz8m9a7	167	17	small	small	JJ
cord-009615-xcz8m9a7	167	18	DNA	dna	NN
cord-009615-xcz8m9a7	167	19	viruses	virus	NNS
cord-009615-xcz8m9a7	167	20	in	in	IN
cord-009615-xcz8m9a7	167	21	demyelinating	demyelinate	VBG
cord-009615-xcz8m9a7	167	22	disease	disease	NN
cord-009615-xcz8m9a7	167	23	,	,	,
cord-009615-xcz8m9a7	167	24	four	four	CD
cord-009615-xcz8m9a7	167	25	different	different	JJ
cord-009615-xcz8m9a7	167	26	animal	animal	NN
cord-009615-xcz8m9a7	167	27	models	model	NNS
cord-009615-xcz8m9a7	167	28	are	be	VBP
cord-009615-xcz8m9a7	167	29	available	available	JJ
cord-009615-xcz8m9a7	167	30	(	(	-LRB-
cord-009615-xcz8m9a7	167	31	Table	table	NN
cord-009615-xcz8m9a7	167	32	1	1	CD
cord-009615-xcz8m9a7	167	33	)	)	-RRB-
cord-009615-xcz8m9a7	167	34	.	.	.
cord-009615-xcz8m9a7	168	1	These	these	DT
cord-009615-xcz8m9a7	168	2	models	model	NNS
cord-009615-xcz8m9a7	168	3	of	of	IN
cord-009615-xcz8m9a7	168	4	polyomavirus	polyomavirus	JJ
cord-009615-xcz8m9a7	168	5	CNS	CNS	NNP
cord-009615-xcz8m9a7	168	6	infection	infection	NN
cord-009615-xcz8m9a7	168	7	include	include	VBP
cord-009615-xcz8m9a7	168	8	simian	simian	JJ
cord-009615-xcz8m9a7	168	9	PML	PML	NNP
cord-009615-xcz8m9a7	168	10	due	due	IN
cord-009615-xcz8m9a7	168	11	to	to	IN
cord-009615-xcz8m9a7	168	12	SV40	SV40	NNP
cord-009615-xcz8m9a7	168	13	in	in	IN
cord-009615-xcz8m9a7	168	14	the	the	DT
cord-009615-xcz8m9a7	168	15	context	context	NN
cord-009615-xcz8m9a7	168	16	of	of	IN
cord-009615-xcz8m9a7	168	17	simian	simian	JJ
cord-009615-xcz8m9a7	168	18	AIDS	AIDS	NNP
cord-009615-xcz8m9a7	168	19	(	(	-LRB-
cord-009615-xcz8m9a7	168	20	74	74	CD
cord-009615-xcz8m9a7	168	21	-	-	SYM
cord-009615-xcz8m9a7	168	22	77	77	CD
cord-009615-xcz8m9a7	168	23	)	)	-RRB-
cord-009615-xcz8m9a7	168	24	,	,	,
cord-009615-xcz8m9a7	168	25	and	and	CC
cord-009615-xcz8m9a7	168	26	the	the	DT
cord-009615-xcz8m9a7	168	27	neonatal	neonatal	JJ
cord-009615-xcz8m9a7	168	28	hamster	hamster	NN
cord-009615-xcz8m9a7	168	29	brain	brain	NN
cord-009615-xcz8m9a7	168	30	infectjon	infectjon	NNP
cord-009615-xcz8m9a7	168	31	(	(	-LRB-
cord-009615-xcz8m9a7	168	32	67	67	CD
cord-009615-xcz8m9a7	168	33	,	,	,
cord-009615-xcz8m9a7	168	34	124	124	CD
cord-009615-xcz8m9a7	168	35	,	,	,
cord-009615-xcz8m9a7	168	36	127	127	CD
cord-009615-xcz8m9a7	168	37	)	)	-RRB-
cord-009615-xcz8m9a7	168	38	with	with	IN
cord-009615-xcz8m9a7	168	39	persistence	persistence	NN
cord-009615-xcz8m9a7	168	40	of	of	IN
cord-009615-xcz8m9a7	168	41	JCV	JCV	NNP
cord-009615-xcz8m9a7	168	42	in	in	IN
cord-009615-xcz8m9a7	168	43	brain	brain	NN
cord-009615-xcz8m9a7	168	44	cells	cell	NNS
cord-009615-xcz8m9a7	168	45	(	(	-LRB-
cord-009615-xcz8m9a7	168	46	Ressetar	Ressetar	NNP
cord-009615-xcz8m9a7	168	47	,	,	,
cord-009615-xcz8m9a7	168	48	unpublished	unpublished	JJ
cord-009615-xcz8m9a7	168	49	data	datum	NNS
cord-009615-xcz8m9a7	168	50	)	)	-RRB-
cord-009615-xcz8m9a7	168	51	.	.	.
cord-009615-xcz8m9a7	169	1	Note	note	VB
cord-009615-xcz8m9a7	169	2	that	that	IN
cord-009615-xcz8m9a7	169	3	the	the	DT
cord-009615-xcz8m9a7	169	4	ham-	ham-	XX
cord-009615-xcz8m9a7	169	5	ster	ster	NNP
cord-009615-xcz8m9a7	169	6	brain	brain	NN
cord-009615-xcz8m9a7	169	7	infection	infection	NN
cord-009615-xcz8m9a7	169	8	currently	currently	RB
cord-009615-xcz8m9a7	169	9	provides	provide	VBZ
cord-009615-xcz8m9a7	169	10	a	a	DT
cord-009615-xcz8m9a7	169	11	model	model	NN
cord-009615-xcz8m9a7	169	12	of	of	IN
cord-009615-xcz8m9a7	169	13	brain	brain	NN
cord-009615-xcz8m9a7	169	14	tumor	tumor	NN
cord-009615-xcz8m9a7	169	15	induction	induction	NN
cord-009615-xcz8m9a7	169	16	and	and	CC
cord-009615-xcz8m9a7	169	17	brain	brain	NN
cord-009615-xcz8m9a7	169	18	endothelial	endothelial	JJ
cord-009615-xcz8m9a7	169	19	cell	cell	NN
cord-009615-xcz8m9a7	169	20	infection	infection	NN
cord-009615-xcz8m9a7	169	21	by	by	IN
cord-009615-xcz8m9a7	169	22	JCV	JCV	NNP
cord-009615-xcz8m9a7	169	23	(	(	-LRB-
cord-009615-xcz8m9a7	169	24	124	124	CD
cord-009615-xcz8m9a7	169	25	,	,	,
cord-009615-xcz8m9a7	169	26	127	127	CD
cord-009615-xcz8m9a7	169	27	)	)	-RRB-
cord-009615-xcz8m9a7	169	28	.	.	.
cord-009615-xcz8m9a7	170	1	Additional	additional	JJ
cord-009615-xcz8m9a7	170	2	experimental	experimental	JJ
cord-009615-xcz8m9a7	170	3	manipulation	manipulation	NN
cord-009615-xcz8m9a7	170	4	will	will	MD
cord-009615-xcz8m9a7	170	5	likely	likely	RB
cord-009615-xcz8m9a7	170	6	be	be	VB
cord-009615-xcz8m9a7	170	7	required	require	VBN
cord-009615-xcz8m9a7	170	8	to	to	TO
cord-009615-xcz8m9a7	170	9	create	create	VB
cord-009615-xcz8m9a7	170	10	a	a	DT
cord-009615-xcz8m9a7	170	11	model	model	NN
cord-009615-xcz8m9a7	170	12	of	of	IN
cord-009615-xcz8m9a7	170	13	immune	immune	NN
cord-009615-xcz8m9a7	170	14	-	-	HYPH
cord-009615-xcz8m9a7	170	15	mediated	mediate	VBN
cord-009615-xcz8m9a7	170	16	demyelination	demyelination	NN
cord-009615-xcz8m9a7	170	17	triggered	trigger	VBN
cord-009615-xcz8m9a7	170	18	by	by	IN
cord-009615-xcz8m9a7	170	19	polyomavirus	polyomavirus	JJ
cord-009615-xcz8m9a7	170	20	antigen	antigen	NN
cord-009615-xcz8m9a7	170	21	in	in	IN
cord-009615-xcz8m9a7	170	22	hamster	hamster	NN
cord-009615-xcz8m9a7	170	23	glial	glial	NN
cord-009615-xcz8m9a7	170	24	cells	cell	NNS
cord-009615-xcz8m9a7	170	25	.	.	.
cord-009615-xcz8m9a7	171	1	Transgenic	transgenic	JJ
cord-009615-xcz8m9a7	171	2	mice	mouse	NNS
cord-009615-xcz8m9a7	171	3	carrying	carry	VBG
cord-009615-xcz8m9a7	171	4	the	the	DT
cord-009615-xcz8m9a7	171	5	JCV	JCV	NNP
cord-009615-xcz8m9a7	171	6	early	early	JJ
cord-009615-xcz8m9a7	171	7	region	region	NN
cord-009615-xcz8m9a7	171	8	expressed	express	VBN
cord-009615-xcz8m9a7	171	9	in	in	IN
cord-009615-xcz8m9a7	171	10	oligodendrocytes	oligodendrocyte	NNS
cord-009615-xcz8m9a7	171	11	showed	show	VBD
cord-009615-xcz8m9a7	171	12	dysmyelination	dysmyelination	NN
cord-009615-xcz8m9a7	171	13	in	in	IN
cord-009615-xcz8m9a7	171	14	the	the	DT
cord-009615-xcz8m9a7	171	15	CNS	CNS	NNP
cord-009615-xcz8m9a7	171	16	in	in	IN
cord-009615-xcz8m9a7	171	17	the	the	DT
cord-009615-xcz8m9a7	171	18	second	second	JJ
cord-009615-xcz8m9a7	171	19	generation	generation	NN
cord-009615-xcz8m9a7	171	20	(	(	-LRB-
cord-009615-xcz8m9a7	171	21	149	149	CD
cord-009615-xcz8m9a7	171	22	)	)	-RRB-
cord-009615-xcz8m9a7	171	23	.	.	.
cord-009615-xcz8m9a7	172	1	In	in	IN
cord-009615-xcz8m9a7	172	2	another	another	DT
cord-009615-xcz8m9a7	172	3	transgenic	transgenic	JJ
cord-009615-xcz8m9a7	172	4	mouse	mouse	NN
cord-009615-xcz8m9a7	172	5	model	model	NN
cord-009615-xcz8m9a7	172	6	,	,	,
cord-009615-xcz8m9a7	172	7	severe	severe	JJ
cord-009615-xcz8m9a7	172	8	dysmyelination	dysmyelination	NN
cord-009615-xcz8m9a7	172	9	occurred	occur	VBD
cord-009615-xcz8m9a7	172	10	in	in	IN
cord-009615-xcz8m9a7	172	11	animals	animal	NNS
cord-009615-xcz8m9a7	172	12	carrying	carry	VBG
cord-009615-xcz8m9a7	172	13	mouse	mouse	NN
cord-009615-xcz8m9a7	172	14	polyoma	polyoma	NNP
cord-009615-xcz8m9a7	172	15	virus	virus	NN
cord-009615-xcz8m9a7	172	16	T	T	NNP
cord-009615-xcz8m9a7	172	17	-	-	HYPH
cord-009615-xcz8m9a7	172	18	antigen	antigen	NN
cord-009615-xcz8m9a7	172	19	DNA	dna	NN
cord-009615-xcz8m9a7	172	20	which	which	WDT
cord-009615-xcz8m9a7	172	21	was	be	VBD
cord-009615-xcz8m9a7	172	22	expressed	express	VBN
cord-009615-xcz8m9a7	172	23	primarily	primarily	RB
cord-009615-xcz8m9a7	172	24	in	in	IN
cord-009615-xcz8m9a7	172	25	astrocytes	astrocyte	NNS
cord-009615-xcz8m9a7	172	26	(	(	-LRB-
cord-009615-xcz8m9a7	172	27	151	151	CD
cord-009615-xcz8m9a7	172	28	)	)	-RRB-
cord-009615-xcz8m9a7	172	29	.	.	.
cord-009615-xcz8m9a7	173	1	This	this	DT
cord-009615-xcz8m9a7	173	2	finding	find	VBG
cord-009615-xcz8m9a7	173	3	points	point	NNS
cord-009615-xcz8m9a7	173	4	toward	toward	IN
cord-009615-xcz8m9a7	173	5	a	a	DT
cord-009615-xcz8m9a7	173	6	key	key	JJ
cord-009615-xcz8m9a7	173	7	role	role	NN
cord-009615-xcz8m9a7	173	8	for	for	IN
cord-009615-xcz8m9a7	173	9	the	the	DT
cord-009615-xcz8m9a7	173	10	astrocyte	astrocyte	NNP
cord-009615-xcz8m9a7	173	11	in	in	IN
cord-009615-xcz8m9a7	173	12	oligodendrocyte	oligodendrocyte	NNP
cord-009615-xcz8m9a7	173	13	support	support	NN
cord-009615-xcz8m9a7	173	14	and	and	CC
cord-009615-xcz8m9a7	173	15	myelin	myelin	NN
cord-009615-xcz8m9a7	173	16	formation	formation	NN
cord-009615-xcz8m9a7	173	17	and	and	CC
cord-009615-xcz8m9a7	173	18	maintenance	maintenance	NN
cord-009615-xcz8m9a7	173	19	.	.	.
cord-009615-xcz8m9a7	174	1	There	there	EX
cord-009615-xcz8m9a7	174	2	are	be	VBP
cord-009615-xcz8m9a7	174	3	more	more	JJR
cord-009615-xcz8m9a7	174	4	data	datum	NNS
cord-009615-xcz8m9a7	174	5	available	available	JJ
cord-009615-xcz8m9a7	174	6	in	in	IN
cord-009615-xcz8m9a7	174	7	all	all	DT
cord-009615-xcz8m9a7	174	8	medical	medical	JJ
cord-009615-xcz8m9a7	174	9	disciplines	discipline	NNS
cord-009615-xcz8m9a7	174	10	for	for	IN
cord-009615-xcz8m9a7	174	11	MS	MS	NNP
cord-009615-xcz8m9a7	174	12	than	than	IN
cord-009615-xcz8m9a7	174	13	for	for	IN
cord-009615-xcz8m9a7	174	14	any	any	DT
cord-009615-xcz8m9a7	174	15	other	other	JJ
cord-009615-xcz8m9a7	174	16	neurological	neurological	JJ
cord-009615-xcz8m9a7	174	17	disease	disease	NN
cord-009615-xcz8m9a7	174	18	,	,	,
cord-009615-xcz8m9a7	174	19	yet	yet	CC
cord-009615-xcz8m9a7	174	20	its	-PRON-	PRP$
cord-009615-xcz8m9a7	174	21	etiopathogenesis	etiopathogenesis	NN
cord-009615-xcz8m9a7	174	22	remains	remain	VBZ
cord-009615-xcz8m9a7	174	23	mysterious	mysterious	JJ
cord-009615-xcz8m9a7	174	24	.	.	.
cord-009615-xcz8m9a7	175	1	Could	Could	MD
cord-009615-xcz8m9a7	175	2	brain	brain	VB
cord-009615-xcz8m9a7	175	3	infection	infection	NN
cord-009615-xcz8m9a7	175	4	with	with	IN
cord-009615-xcz8m9a7	175	5	a	a	DT
cord-009615-xcz8m9a7	175	6	latent	latent	JJ
cord-009615-xcz8m9a7	175	7	virus	virus	NN
cord-009615-xcz8m9a7	175	8	capable	capable	JJ
cord-009615-xcz8m9a7	175	9	of	of	IN
cord-009615-xcz8m9a7	175	10	limited	limited	JJ
cord-009615-xcz8m9a7	175	11	reactivation	reactivation	NN
cord-009615-xcz8m9a7	175	12	in	in	IN
cord-009615-xcz8m9a7	175	13	glial	glial	JJ
cord-009615-xcz8m9a7	175	14	cells	cell	NNS
cord-009615-xcz8m9a7	175	15	explain	explain	VBP
cord-009615-xcz8m9a7	175	16	this	this	DT
cord-009615-xcz8m9a7	175	17	wealth	wealth	NN
cord-009615-xcz8m9a7	175	18	of	of	IN
cord-009615-xcz8m9a7	175	19	data	datum	NNS
cord-009615-xcz8m9a7	175	20	?	?	.
cord-009615-xcz8m9a7	176	1	The	the	DT
cord-009615-xcz8m9a7	176	2	example	example	NN
cord-009615-xcz8m9a7	176	3	of	of	IN
cord-009615-xcz8m9a7	176	4	the	the	DT
cord-009615-xcz8m9a7	176	5	polyomaviruses	polyomaviruse	NNS
cord-009615-xcz8m9a7	176	6	suggests	suggest	VBZ
cord-009615-xcz8m9a7	176	7	that	that	IN
cord-009615-xcz8m9a7	176	8	it	-PRON-	PRP
cord-009615-xcz8m9a7	176	9	could	could	MD
cord-009615-xcz8m9a7	176	10	.	.	.
cord-009615-xcz8m9a7	177	1	Unfortunately	unfortunately	RB
cord-009615-xcz8m9a7	177	2	,	,	,
cord-009615-xcz8m9a7	177	3	our	-PRON-	PRP$
cord-009615-xcz8m9a7	177	4	knowledge	knowledge	NN
cord-009615-xcz8m9a7	177	5	of	of	IN
cord-009615-xcz8m9a7	177	6	the	the	DT
cord-009615-xcz8m9a7	177	7	natural	natural	JJ
cord-009615-xcz8m9a7	177	8	history	history	NN
cord-009615-xcz8m9a7	177	9	of	of	IN
cord-009615-xcz8m9a7	177	10	polyomavirus	polyomavirus	JJ
cord-009615-xcz8m9a7	177	11	infections	infection	NNS
cord-009615-xcz8m9a7	177	12	of	of	IN
cord-009615-xcz8m9a7	177	13	humans	human	NNS
cord-009615-xcz8m9a7	177	14	is	be	VBZ
cord-009615-xcz8m9a7	177	15	still	still	RB
cord-009615-xcz8m9a7	177	16	fragmentary	fragmentary	JJ
cord-009615-xcz8m9a7	177	17	,	,	,
cord-009615-xcz8m9a7	177	18	and	and	CC
cord-009615-xcz8m9a7	177	19	there	there	EX
cord-009615-xcz8m9a7	177	20	is	be	VBZ
cord-009615-xcz8m9a7	177	21	very	very	RB
cord-009615-xcz8m9a7	177	22	little	little	JJ
cord-009615-xcz8m9a7	177	23	data	datum	NNS
cord-009615-xcz8m9a7	177	24	available	available	JJ
cord-009615-xcz8m9a7	177	25	on	on	IN
cord-009615-xcz8m9a7	177	26	these	these	DT
cord-009615-xcz8m9a7	177	27	infections	infection	NNS
cord-009615-xcz8m9a7	177	28	in	in	IN
cord-009615-xcz8m9a7	177	29	relation	relation	NN
cord-009615-xcz8m9a7	177	30	to	to	IN
cord-009615-xcz8m9a7	177	31	MS	MS	NNP
cord-009615-xcz8m9a7	177	32	.	.	.
cord-009615-xcz8m9a7	178	1	Although	although	IN
cord-009615-xcz8m9a7	178	2	JCV	JCV	NNP
cord-009615-xcz8m9a7	178	3	was	be	VBD
cord-009615-xcz8m9a7	178	4	first	first	RB
cord-009615-xcz8m9a7	178	5	cultured	cultured	JJ
cord-009615-xcz8m9a7	178	6	and	and	CC
cord-009615-xcz8m9a7	178	7	characterized	characterize	VBN
cord-009615-xcz8m9a7	178	8	in	in	IN
cord-009615-xcz8m9a7	178	9	1971	1971	CD
cord-009615-xcz8m9a7	178	10	(	(	-LRB-
cord-009615-xcz8m9a7	178	11	46	46	CD
cord-009615-xcz8m9a7	178	12	)	)	-RRB-
cord-009615-xcz8m9a7	178	13	,	,	,
cord-009615-xcz8m9a7	178	14	primary	primary	JJ
cord-009615-xcz8m9a7	178	15	JCV	JCV	NNP
cord-009615-xcz8m9a7	178	16	infections	infection	NNS
cord-009615-xcz8m9a7	178	17	in	in	IN
cord-009615-xcz8m9a7	178	18	humans	human	NNS
cord-009615-xcz8m9a7	178	19	have	have	VBP
cord-009615-xcz8m9a7	178	20	never	never	RB
cord-009615-xcz8m9a7	178	21	been	be	VBN
cord-009615-xcz8m9a7	178	22	identi	identi	VBN
cord-009615-xcz8m9a7	178	23	-	-	HYPH
cord-009615-xcz8m9a7	178	24	fied	fied	JJ
cord-009615-xcz8m9a7	178	25	and	and	CC
cord-009615-xcz8m9a7	178	26	have	have	VBP
cord-009615-xcz8m9a7	178	27	therefore	therefore	RB
cord-009615-xcz8m9a7	178	28	been	be	VBN
cord-009615-xcz8m9a7	178	29	impossible	impossible	JJ
cord-009615-xcz8m9a7	178	30	to	to	TO
cord-009615-xcz8m9a7	178	31	study	study	VB
cord-009615-xcz8m9a7	178	32	.	.	.
cord-009615-xcz8m9a7	179	1	Serological	serological	JJ
cord-009615-xcz8m9a7	179	2	tests	test	NNS
cord-009615-xcz8m9a7	179	3	are	be	VBP
cord-009615-xcz8m9a7	179	4	presently	presently	RB
cord-009615-xcz8m9a7	179	5	the	the	DT
cord-009615-xcz8m9a7	179	6	only	only	JJ
cord-009615-xcz8m9a7	179	7	available	available	JJ
cord-009615-xcz8m9a7	179	8	indicator	indicator	NN
cord-009615-xcz8m9a7	179	9	of	of	IN
cord-009615-xcz8m9a7	179	10	acquisition	acquisition	NN
cord-009615-xcz8m9a7	179	11	of	of	IN
cord-009615-xcz8m9a7	179	12	this	this	DT
cord-009615-xcz8m9a7	179	13	(	(	-LRB-
cord-009615-xcz8m9a7	179	14	apparently	apparently	RB
cord-009615-xcz8m9a7	179	15	)	)	-RRB-
cord-009615-xcz8m9a7	179	16	silent	silent	JJ
cord-009615-xcz8m9a7	179	17	initial	initial	JJ
cord-009615-xcz8m9a7	179	18	infection	infection	NN
cord-009615-xcz8m9a7	179	19	.	.	.
cord-009615-xcz8m9a7	180	1	The	the	DT
cord-009615-xcz8m9a7	180	2	most	most	RBS
cord-009615-xcz8m9a7	180	3	widely	widely	RB
cord-009615-xcz8m9a7	180	4	used	use	VBN
cord-009615-xcz8m9a7	180	5	antibody	antibody	NN
cord-009615-xcz8m9a7	180	6	assay	assay	NN
cord-009615-xcz8m9a7	180	7	,	,	,
cord-009615-xcz8m9a7	180	8	hemagglutination	hemagglutination	NN
cord-009615-xcz8m9a7	180	9	inhibition	inhibition	NN
cord-009615-xcz8m9a7	180	10	,	,	,
cord-009615-xcz8m9a7	180	11	requires	require	VBZ
cord-009615-xcz8m9a7	180	12	large	large	JJ
cord-009615-xcz8m9a7	180	13	amounts	amount	NNS
cord-009615-xcz8m9a7	180	14	of	of	IN
cord-009615-xcz8m9a7	180	15	the	the	DT
cord-009615-xcz8m9a7	180	16	virus	virus	NN
cord-009615-xcz8m9a7	180	17	which	which	WDT
cord-009615-xcz8m9a7	180	18	is	be	VBZ
cord-009615-xcz8m9a7	180	19	in	in	IN
cord-009615-xcz8m9a7	180	20	limited	limited	JJ
cord-009615-xcz8m9a7	180	21	supply	supply	NN
cord-009615-xcz8m9a7	180	22	due	due	IN
cord-009615-xcz8m9a7	180	23	to	to	IN
cord-009615-xcz8m9a7	180	24	the	the	DT
cord-009615-xcz8m9a7	180	25	difficulty	difficulty	NN
cord-009615-xcz8m9a7	180	26	with	with	IN
cord-009615-xcz8m9a7	180	27	which	which	WDT
cord-009615-xcz8m9a7	180	28	JCV	JCV	NNP
cord-009615-xcz8m9a7	180	29	is	be	VBZ
cord-009615-xcz8m9a7	180	30	cultured	culture	VBN
cord-009615-xcz8m9a7	180	31	in	in	IN
cord-009615-xcz8m9a7	180	32	primary	primary	JJ
cord-009615-xcz8m9a7	180	33	human	human	JJ
cord-009615-xcz8m9a7	180	34	fetal	fetal	JJ
cord-009615-xcz8m9a7	180	35	glial	glial	JJ
cord-009615-xcz8m9a7	180	36	cells	cell	NNS
cord-009615-xcz8m9a7	180	37	(	(	-LRB-
cord-009615-xcz8m9a7	180	38	152	152	CD
cord-009615-xcz8m9a7	180	39	)	)	-RRB-
cord-009615-xcz8m9a7	180	40	.	.	.
cord-009615-xcz8m9a7	181	1	A	a	DT
cord-009615-xcz8m9a7	181	2	single	single	JJ
cord-009615-xcz8m9a7	181	3	report	report	NN
cord-009615-xcz8m9a7	181	4	on	on	IN
cord-009615-xcz8m9a7	181	5	BKV	BKV	NNP
cord-009615-xcz8m9a7	181	6	serology	serology	NN
cord-009615-xcz8m9a7	181	7	in	in	IN
cord-009615-xcz8m9a7	181	8	MS	MS	NNP
cord-009615-xcz8m9a7	181	9	(	(	-LRB-
cord-009615-xcz8m9a7	181	10	153	153	CD
cord-009615-xcz8m9a7	181	11	)	)	-RRB-
cord-009615-xcz8m9a7	181	12	did	do	VBD
cord-009615-xcz8m9a7	181	13	not	not	RB
cord-009615-xcz8m9a7	181	14	reveal	reveal	VB
cord-009615-xcz8m9a7	181	15	an	an	DT
cord-009615-xcz8m9a7	181	16	association	association	NN
cord-009615-xcz8m9a7	181	17	.	.	.
cord-009615-xcz8m9a7	182	1	There	there	EX
cord-009615-xcz8m9a7	182	2	is	be	VBZ
cord-009615-xcz8m9a7	182	3	no	no	DT
cord-009615-xcz8m9a7	182	4	published	publish	VBN
cord-009615-xcz8m9a7	182	5	information	information	NN
cord-009615-xcz8m9a7	182	6	on	on	IN
cord-009615-xcz8m9a7	182	7	JCV	JCV	NNP
cord-009615-xcz8m9a7	182	8	serology	serology	NN
cord-009615-xcz8m9a7	182	9	in	in	IN
cord-009615-xcz8m9a7	182	10	relation	relation	NN
cord-009615-xcz8m9a7	182	11	to	to	IN
cord-009615-xcz8m9a7	182	12	MS	MS	NNP
cord-009615-xcz8m9a7	182	13	.	.	.
cord-009615-xcz8m9a7	183	1	With	with	IN
cord-009615-xcz8m9a7	183	2	respect	respect	NN
cord-009615-xcz8m9a7	183	3	to	to	IN
cord-009615-xcz8m9a7	183	4	pathology	pathology	NN
cord-009615-xcz8m9a7	183	5	,	,	,
cord-009615-xcz8m9a7	183	6	a	a	DT
cord-009615-xcz8m9a7	183	7	systematic	systematic	JJ
cord-009615-xcz8m9a7	183	8	comparison	comparison	NN
cord-009615-xcz8m9a7	183	9	of	of	IN
cord-009615-xcz8m9a7	183	10	lesion	lesion	NN
cord-009615-xcz8m9a7	183	11	development	development	NN
cord-009615-xcz8m9a7	183	12	and	and	CC
cord-009615-xcz8m9a7	183	13	distribution	distribution	NN
cord-009615-xcz8m9a7	183	14	in	in	IN
cord-009615-xcz8m9a7	183	15	PML	PML	NNP
cord-009615-xcz8m9a7	183	16	and	and	CC
cord-009615-xcz8m9a7	183	17	MS	MS	NNP
cord-009615-xcz8m9a7	183	18	brains	brain	NNS
cord-009615-xcz8m9a7	183	19	has	have	VBZ
cord-009615-xcz8m9a7	183	20	never	never	RB
cord-009615-xcz8m9a7	183	21	been	be	VBN
cord-009615-xcz8m9a7	183	22	reported	report	VBN
cord-009615-xcz8m9a7	183	23	.	.	.
cord-009615-xcz8m9a7	184	1	However	however	RB
cord-009615-xcz8m9a7	184	2	,	,	,
cord-009615-xcz8m9a7	184	3	comparison	comparison	NN
cord-009615-xcz8m9a7	184	4	of	of	IN
cord-009615-xcz8m9a7	184	5	the	the	DT
cord-009615-xcz8m9a7	184	6	recognized	recognize	VBN
cord-009615-xcz8m9a7	184	7	pathological	pathological	JJ
cord-009615-xcz8m9a7	184	8	features	feature	NNS
cord-009615-xcz8m9a7	184	9	of	of	IN
cord-009615-xcz8m9a7	184	10	each	each	DT
cord-009615-xcz8m9a7	184	11	disease	disease	NN
cord-009615-xcz8m9a7	184	12	suggests	suggest	VBZ
cord-009615-xcz8m9a7	184	13	some	some	DT
cord-009615-xcz8m9a7	184	14	interesting	interesting	JJ
cord-009615-xcz8m9a7	184	15	parallels	parallel	NNS
cord-009615-xcz8m9a7	184	16	(	(	-LRB-
cord-009615-xcz8m9a7	184	17	98	98	CD
cord-009615-xcz8m9a7	184	18	)	)	-RRB-
cord-009615-xcz8m9a7	184	19	.	.	.
cord-009615-xcz8m9a7	185	1	It	-PRON-	PRP
cord-009615-xcz8m9a7	185	2	is	be	VBZ
cord-009615-xcz8m9a7	185	3	noteworthy	noteworthy	JJ
cord-009615-xcz8m9a7	185	4	that	that	IN
cord-009615-xcz8m9a7	185	5	the	the	DT
cord-009615-xcz8m9a7	185	6	very	very	RB
cord-009615-xcz8m9a7	185	7	small	small	JJ
cord-009615-xcz8m9a7	185	8	early	early	JJ
cord-009615-xcz8m9a7	185	9	foci	focus	NNS
cord-009615-xcz8m9a7	185	10	described	describe	VBN
cord-009615-xcz8m9a7	185	11	for	for	IN
cord-009615-xcz8m9a7	185	12	PML	PML	NNP
cord-009615-xcz8m9a7	185	13	(	(	-LRB-
cord-009615-xcz8m9a7	185	14	128	128	CD
cord-009615-xcz8m9a7	185	15	)	)	-RRB-
cord-009615-xcz8m9a7	185	16	(	(	-LRB-
cord-009615-xcz8m9a7	185	17	129	129	CD
cord-009615-xcz8m9a7	185	18	)	)	-RRB-
cord-009615-xcz8m9a7	185	19	(	(	-LRB-
cord-009615-xcz8m9a7	185	20	130	130	CD
cord-009615-xcz8m9a7	185	21	)	)	-RRB-
cord-009615-xcz8m9a7	185	22	(	(	-LRB-
cord-009615-xcz8m9a7	185	23	131	131	CD
cord-009615-xcz8m9a7	185	24	)	)	-RRB-
cord-009615-xcz8m9a7	185	25	(	(	-LRB-
cord-009615-xcz8m9a7	185	26	132	132	CD
cord-009615-xcz8m9a7	185	27	)	)	-RRB-
cord-009615-xcz8m9a7	185	28	are	be	VBP
cord-009615-xcz8m9a7	185	29	in	in	IN
cord-009615-xcz8m9a7	185	30	some	some	DT
cord-009615-xcz8m9a7	185	31	ways	way	NNS
cord-009615-xcz8m9a7	185	32	reminiscent	reminiscent	JJ
cord-009615-xcz8m9a7	185	33	of	of	IN
cord-009615-xcz8m9a7	185	34	the	the	DT
cord-009615-xcz8m9a7	185	35	earliest	early	JJS
cord-009615-xcz8m9a7	185	36	MS	MS	NNP
cord-009615-xcz8m9a7	185	37	lesions	lesion	NNS
cord-009615-xcz8m9a7	185	38	as	as	IN
cord-009615-xcz8m9a7	185	39	described	describe	VBN
cord-009615-xcz8m9a7	185	40	by	by	IN
cord-009615-xcz8m9a7	185	41	Lumsden	Lumsden	NNP
cord-009615-xcz8m9a7	185	42	(	(	-LRB-
cord-009615-xcz8m9a7	185	43	2	2	CD
cord-009615-xcz8m9a7	185	44	)	)	-RRB-
cord-009615-xcz8m9a7	185	45	.	.	.
cord-009615-xcz8m9a7	186	1	(	(	-LRB-
cord-009615-xcz8m9a7	186	2	For	for	IN
cord-009615-xcz8m9a7	186	3	discussion	discussion	NN
cord-009615-xcz8m9a7	186	4	of	of	IN
cord-009615-xcz8m9a7	186	5	early	early	JJ
cord-009615-xcz8m9a7	186	6	MS	MS	NNP
cord-009615-xcz8m9a7	186	7	pathology	pathology	NN
cord-009615-xcz8m9a7	186	8	see	see	VBP
cord-009615-xcz8m9a7	186	9	also	also	RB
cord-009615-xcz8m9a7	186	10	reference	reference	NN
cord-009615-xcz8m9a7	186	11	154	154	CD
cord-009615-xcz8m9a7	186	12	)	)	-RRB-
cord-009615-xcz8m9a7	186	13	.	.	.
cord-009615-xcz8m9a7	187	1	The	the	DT
cord-009615-xcz8m9a7	187	2	relationship	relationship	NN
cord-009615-xcz8m9a7	187	3	of	of	IN
cord-009615-xcz8m9a7	187	4	many	many	JJ
cord-009615-xcz8m9a7	187	5	small	small	JJ
cord-009615-xcz8m9a7	187	6	MS	MS	NNP
cord-009615-xcz8m9a7	187	7	plaques	plaque	NNS
cord-009615-xcz8m9a7	187	8	to	to	IN
cord-009615-xcz8m9a7	187	9	the	the	DT
cord-009615-xcz8m9a7	187	10	course	course	NN
cord-009615-xcz8m9a7	187	11	of	of	IN
cord-009615-xcz8m9a7	187	12	a	a	DT
cord-009615-xcz8m9a7	187	13	vessel	vessel	NN
cord-009615-xcz8m9a7	187	14	(	(	-LRB-
cord-009615-xcz8m9a7	187	15	2,155	2,155	CD
cord-009615-xcz8m9a7	187	16	)	)	-RRB-
cord-009615-xcz8m9a7	187	17	is	be	VBZ
cord-009615-xcz8m9a7	187	18	consistent	consistent	JJ
cord-009615-xcz8m9a7	187	19	with	with	IN
cord-009615-xcz8m9a7	187	20	the	the	DT
cord-009615-xcz8m9a7	187	21	proposed	propose	VBN
cord-009615-xcz8m9a7	187	22	route	route	NN
cord-009615-xcz8m9a7	187	23	of	of	IN
cord-009615-xcz8m9a7	187	24	polyomavirus	polyomavirus	NNP
cord-009615-xcz8m9a7	187	25	entry	entry	NN
cord-009615-xcz8m9a7	187	26	into	into	IN
cord-009615-xcz8m9a7	187	27	the	the	DT
cord-009615-xcz8m9a7	187	28	CNS	CNS	NNP
cord-009615-xcz8m9a7	187	29	.	.	.
cord-009615-xcz8m9a7	188	1	At	at	IN
cord-009615-xcz8m9a7	188	2	onset	onset	NN
cord-009615-xcz8m9a7	188	3	the	the	DT
cord-009615-xcz8m9a7	188	4	topology	topology	NN
cord-009615-xcz8m9a7	188	5	of	of	IN
cord-009615-xcz8m9a7	188	6	MS	MS	NNP
cord-009615-xcz8m9a7	188	7	lesions	lesion	NNS
cord-009615-xcz8m9a7	188	8	may	may	MD
cord-009615-xcz8m9a7	188	9	be	be	VB
cord-009615-xcz8m9a7	188	10	defined	define	VBN
cord-009615-xcz8m9a7	188	11	in	in	IN
cord-009615-xcz8m9a7	188	12	large	large	JJ
cord-009615-xcz8m9a7	188	13	part	part	NN
cord-009615-xcz8m9a7	188	14	by	by	IN
cord-009615-xcz8m9a7	188	15	the	the	DT
cord-009615-xcz8m9a7	188	16	distribution	distribution	NN
cord-009615-xcz8m9a7	188	17	of	of	IN
cord-009615-xcz8m9a7	188	18	viral	viral	JJ
cord-009615-xcz8m9a7	188	19	antigen	antigen	NN
cord-009615-xcz8m9a7	188	20	along	along	IN
cord-009615-xcz8m9a7	188	21	the	the	DT
cord-009615-xcz8m9a7	188	22	pathway	pathway	NN
cord-009615-xcz8m9a7	188	23	taken	take	VBN
cord-009615-xcz8m9a7	188	24	by	by	IN
cord-009615-xcz8m9a7	188	25	the	the	DT
cord-009615-xcz8m9a7	188	26	virus	virus	NN
cord-009615-xcz8m9a7	188	27	on	on	IN
cord-009615-xcz8m9a7	188	28	leaving	leave	VBG
cord-009615-xcz8m9a7	188	29	the	the	DT
cord-009615-xcz8m9a7	188	30	circulation	circulation	NN
cord-009615-xcz8m9a7	188	31	and	and	CC
cord-009615-xcz8m9a7	188	32	entering	enter	VBG
cord-009615-xcz8m9a7	188	33	the	the	DT
cord-009615-xcz8m9a7	188	34	brain	brain	NN
cord-009615-xcz8m9a7	188	35	.	.	.
cord-009615-xcz8m9a7	189	1	This	this	DT
cord-009615-xcz8m9a7	189	2	path	path	NN
cord-009615-xcz8m9a7	189	3	could	could	MD
cord-009615-xcz8m9a7	189	4	be	be	VB
cord-009615-xcz8m9a7	189	5	within	within	IN
cord-009615-xcz8m9a7	189	6	dividing	divide	VBG
cord-009615-xcz8m9a7	189	7	cells	cell	NNS
cord-009615-xcz8m9a7	189	8	or	or	CC
cord-009615-xcz8m9a7	189	9	between	between	IN
cord-009615-xcz8m9a7	189	10	cells	cell	NNS
cord-009615-xcz8m9a7	189	11	in	in	IN
cord-009615-xcz8m9a7	189	12	contact	contact	NN
cord-009615-xcz8m9a7	189	13	,	,	,
cord-009615-xcz8m9a7	189	14	or	or	CC
cord-009615-xcz8m9a7	189	15	both	both	DT
cord-009615-xcz8m9a7	189	16	.	.	.
cord-009615-xcz8m9a7	190	1	Recent	recent	JJ
cord-009615-xcz8m9a7	190	2	neuroimaging	neuroimaging	NN
cord-009615-xcz8m9a7	190	3	data	datum	NNS
cord-009615-xcz8m9a7	190	4	suggest	suggest	VBP
cord-009615-xcz8m9a7	190	5	that	that	IN
cord-009615-xcz8m9a7	190	6	disturbance	disturbance	NN
cord-009615-xcz8m9a7	190	7	of	of	IN
cord-009615-xcz8m9a7	190	8	the	the	DT
cord-009615-xcz8m9a7	190	9	blood	blood	NN
cord-009615-xcz8m9a7	190	10	-	-	HYPH
cord-009615-xcz8m9a7	190	11	brain	brain	NN
cord-009615-xcz8m9a7	190	12	barrier	barrier	NN
cord-009615-xcz8m9a7	190	13	with	with	IN
cord-009615-xcz8m9a7	190	14	or	or	CC
cord-009615-xcz8m9a7	190	15	without	without	IN
cord-009615-xcz8m9a7	190	16	clinical	clinical	JJ
cord-009615-xcz8m9a7	190	17	symptoms	symptom	NNS
cord-009615-xcz8m9a7	190	18	is	be	VBZ
cord-009615-xcz8m9a7	190	19	the	the	DT
cord-009615-xcz8m9a7	190	20	initial	initial	JJ
cord-009615-xcz8m9a7	190	21	event	event	NN
cord-009615-xcz8m9a7	190	22	in	in	IN
cord-009615-xcz8m9a7	190	23	the	the	DT
cord-009615-xcz8m9a7	190	24	development	development	NN
cord-009615-xcz8m9a7	190	25	of	of	IN
cord-009615-xcz8m9a7	190	26	new	new	JJ
cord-009615-xcz8m9a7	190	27	demyelinated	demyelinated	JJ
cord-009615-xcz8m9a7	190	28	lesions	lesion	NNS
cord-009615-xcz8m9a7	190	29	in	in	IN
cord-009615-xcz8m9a7	190	30	relapsing	relapse	VBG
cord-009615-xcz8m9a7	190	31	/	/	SYM
cord-009615-xcz8m9a7	190	32	remitting	remit	VBG
cord-009615-xcz8m9a7	190	33	MS	MS	NNP
cord-009615-xcz8m9a7	190	34	(	(	-LRB-
cord-009615-xcz8m9a7	190	35	103	103	CD
cord-009615-xcz8m9a7	190	36	,	,	,
cord-009615-xcz8m9a7	190	37	156	156	CD
cord-009615-xcz8m9a7	190	38	,	,	,
cord-009615-xcz8m9a7	190	39	157	157	CD
cord-009615-xcz8m9a7	190	40	)	)	-RRB-
cord-009615-xcz8m9a7	190	41	.	.	.
cord-009615-xcz8m9a7	191	1	These	these	DT
cord-009615-xcz8m9a7	191	2	findings	finding	NNS
cord-009615-xcz8m9a7	191	3	emphasize	emphasize	VBP
cord-009615-xcz8m9a7	191	4	a	a	DT
cord-009615-xcz8m9a7	191	5	role	role	NN
cord-009615-xcz8m9a7	191	6	for	for	IN
cord-009615-xcz8m9a7	191	7	the	the	DT
cord-009615-xcz8m9a7	191	8	endothelium	endothelium	NN
cord-009615-xcz8m9a7	191	9	in	in	IN
cord-009615-xcz8m9a7	191	10	MS	MS	NNP
cord-009615-xcz8m9a7	191	11	lesion	lesion	NN
cord-009615-xcz8m9a7	191	12	pathogenesis	pathogenesis	NN
cord-009615-xcz8m9a7	191	13	,	,	,
cord-009615-xcz8m9a7	191	14	and	and	CC
cord-009615-xcz8m9a7	191	15	have	have	VBP
cord-009615-xcz8m9a7	191	16	generally	generally	RB
cord-009615-xcz8m9a7	191	17	been	be	VBN
cord-009615-xcz8m9a7	191	18	interpreted	interpret	VBN
cord-009615-xcz8m9a7	191	19	in	in	IN
cord-009615-xcz8m9a7	191	20	terms	term	NNS
cord-009615-xcz8m9a7	191	21	of	of	IN
cord-009615-xcz8m9a7	191	22	the	the	DT
cord-009615-xcz8m9a7	191	23	EAE	EAE	NNP
cord-009615-xcz8m9a7	191	24	model	model	NN
cord-009615-xcz8m9a7	191	25	(	(	-LRB-
cord-009615-xcz8m9a7	191	26	158	158	CD
cord-009615-xcz8m9a7	191	27	)	)	-RRB-
cord-009615-xcz8m9a7	191	28	.	.	.
cord-009615-xcz8m9a7	192	1	Can	Can	MD
cord-009615-xcz8m9a7	192	2	they	-PRON-	PRP
cord-009615-xcz8m9a7	192	3	also	also	RB
cord-009615-xcz8m9a7	192	4	be	be	VB
cord-009615-xcz8m9a7	192	5	accommodated	accommodate	VBN
cord-009615-xcz8m9a7	192	6	by	by	IN
cord-009615-xcz8m9a7	192	7	a	a	DT
cord-009615-xcz8m9a7	192	8	latent	latent	NN
cord-009615-xcz8m9a7	192	9	-	-	HYPH
cord-009615-xcz8m9a7	192	10	virus	virus	NN
cord-009615-xcz8m9a7	192	11	model	model	NN
cord-009615-xcz8m9a7	192	12	?	?	.
cord-009615-xcz8m9a7	193	1	In	in	IN
cord-009615-xcz8m9a7	193	2	fact	fact	NN
cord-009615-xcz8m9a7	193	3	,	,	,
cord-009615-xcz8m9a7	193	4	as	as	IN
cord-009615-xcz8m9a7	193	5	described	describe	VBN
cord-009615-xcz8m9a7	193	6	above	above	RB
cord-009615-xcz8m9a7	193	7	,	,	,
cord-009615-xcz8m9a7	193	8	JCV	JCV	NNP
cord-009615-xcz8m9a7	193	9	can	can	MD
cord-009615-xcz8m9a7	193	10	infect	infect	VB
cord-009615-xcz8m9a7	193	11	brain	brain	NN
cord-009615-xcz8m9a7	193	12	endothelial	endothelial	JJ
cord-009615-xcz8m9a7	193	13	cells	cell	NNS
cord-009615-xcz8m9a7	193	14	.	.	.
cord-009615-xcz8m9a7	194	1	Productive	productive	JJ
cord-009615-xcz8m9a7	194	2	infection	infection	NN
cord-009615-xcz8m9a7	194	3	of	of	IN
cord-009615-xcz8m9a7	194	4	endothelial	endothelial	JJ
cord-009615-xcz8m9a7	194	5	cells	cell	NNS
cord-009615-xcz8m9a7	194	6	by	by	IN
cord-009615-xcz8m9a7	194	7	JCV	JCV	NNP
cord-009615-xcz8m9a7	194	8	is	be	VBZ
cord-009615-xcz8m9a7	194	9	unusual	unusual	JJ
cord-009615-xcz8m9a7	194	10	in	in	IN
cord-009615-xcz8m9a7	194	11	PML	PML	NNP
cord-009615-xcz8m9a7	194	12	(	(	-LRB-
cord-009615-xcz8m9a7	194	13	122	122	CD
cord-009615-xcz8m9a7	194	14	)	)	-RRB-
cord-009615-xcz8m9a7	194	15	,	,	,
cord-009615-xcz8m9a7	194	16	but	but	CC
cord-009615-xcz8m9a7	194	17	an	an	DT
cord-009615-xcz8m9a7	194	18	abortive	abortive	JJ
cord-009615-xcz8m9a7	194	19	infection	infection	NN
cord-009615-xcz8m9a7	194	20	of	of	IN
cord-009615-xcz8m9a7	194	21	hamster	hamster	NN
cord-009615-xcz8m9a7	194	22	endothelial	endothelial	JJ
cord-009615-xcz8m9a7	194	23	cells	cell	NNS
cord-009615-xcz8m9a7	194	24	in	in	IN
cord-009615-xcz8m9a7	194	25	which	which	WDT
cord-009615-xcz8m9a7	194	26	T	t	NN
cord-009615-xcz8m9a7	194	27	-	-	HYPH
cord-009615-xcz8m9a7	194	28	antigen	antigen	NNP
cord-009615-xcz8m9a7	194	29	is	be	VBZ
cord-009615-xcz8m9a7	194	30	expressed	express	VBN
cord-009615-xcz8m9a7	194	31	at	at	IN
cord-009615-xcz8m9a7	194	32	30	30	CD
cord-009615-xcz8m9a7	194	33	days	day	NNS
cord-009615-xcz8m9a7	194	34	of	of	IN
cord-009615-xcz8m9a7	194	35	age	age	NN
cord-009615-xcz8m9a7	194	36	is	be	VBZ
cord-009615-xcz8m9a7	194	37	particularly	particularly	RB
cord-009615-xcz8m9a7	194	38	pronounced	pronounce	VBN
cord-009615-xcz8m9a7	194	39	following	following	JJ
cord-009615-xcz8m9a7	194	40	immunosuppressive	immunosuppressive	JJ
cord-009615-xcz8m9a7	194	41	treatment	treatment	NN
cord-009615-xcz8m9a7	194	42	with	with	IN
cord-009615-xcz8m9a7	194	43	cyclophosphamide	cyclophosphamide	NN
cord-009615-xcz8m9a7	194	44	(	(	-LRB-
cord-009615-xcz8m9a7	194	45	124	124	CD
cord-009615-xcz8m9a7	194	46	)	)	-RRB-
cord-009615-xcz8m9a7	194	47	.	.	.
cord-009615-xcz8m9a7	195	1	Thus	thus	RB
cord-009615-xcz8m9a7	195	2	,	,	,
cord-009615-xcz8m9a7	195	3	initiating	initiate	VBG
cord-009615-xcz8m9a7	195	4	events	event	NNS
cord-009615-xcz8m9a7	195	5	at	at	IN
cord-009615-xcz8m9a7	195	6	the	the	DT
cord-009615-xcz8m9a7	195	7	blood	blood	NN
cord-009615-xcz8m9a7	195	8	-	-	HYPH
cord-009615-xcz8m9a7	195	9	brain	brain	NN
cord-009615-xcz8m9a7	195	10	barrier	barrier	NN
cord-009615-xcz8m9a7	195	11	in	in	IN
cord-009615-xcz8m9a7	195	12	MS	MS	NNP
cord-009615-xcz8m9a7	195	13	pathogenesis	pathogenesis	NN
cord-009615-xcz8m9a7	195	14	can	can	MD
cord-009615-xcz8m9a7	195	15	be	be	VB
cord-009615-xcz8m9a7	195	16	accommodated	accommodate	VBN
cord-009615-xcz8m9a7	195	17	by	by	IN
cord-009615-xcz8m9a7	195	18	a	a	DT
cord-009615-xcz8m9a7	195	19	viral	viral	JJ
cord-009615-xcz8m9a7	195	20	hypothesis	hypothesis	NN
cord-009615-xcz8m9a7	195	21	in	in	IN
cord-009615-xcz8m9a7	195	22	which	which	WDT
cord-009615-xcz8m9a7	195	23	immune	immune	JJ
cord-009615-xcz8m9a7	195	24	responses	response	NNS
cord-009615-xcz8m9a7	195	25	targeting	target	VBG
cord-009615-xcz8m9a7	195	26	cells	cell	NNS
cord-009615-xcz8m9a7	195	27	in	in	IN
cord-009615-xcz8m9a7	195	28	the	the	DT
cord-009615-xcz8m9a7	195	29	parenchyma	parenchyma	NN
cord-009615-xcz8m9a7	195	30	follow	follow	VBP
cord-009615-xcz8m9a7	195	31	viral	viral	JJ
cord-009615-xcz8m9a7	195	32	reactivation	reactivation	NN
cord-009615-xcz8m9a7	195	33	in	in	IN
cord-009615-xcz8m9a7	195	34	infected	infected	JJ
cord-009615-xcz8m9a7	195	35	endothelial	endothelial	JJ
cord-009615-xcz8m9a7	195	36	cells	cell	NNS
cord-009615-xcz8m9a7	195	37	nearby	nearby	RB
cord-009615-xcz8m9a7	195	38	,	,	,
cord-009615-xcz8m9a7	195	39	as	as	IN
cord-009615-xcz8m9a7	195	40	originally	originally	RB
cord-009615-xcz8m9a7	195	41	postulated	postulate	VBN
cord-009615-xcz8m9a7	195	42	by	by	IN
cord-009615-xcz8m9a7	195	43	Wisniewski	Wisniewski	NNP
cord-009615-xcz8m9a7	195	44	et	et	NNP
cord-009615-xcz8m9a7	195	45	al	al	NNP
cord-009615-xcz8m9a7	195	46	.	.	.
cord-009615-xcz8m9a7	196	1	(	(	-LRB-
cord-009615-xcz8m9a7	196	2	3	3	CD
cord-009615-xcz8m9a7	196	3	)	)	-RRB-
cord-009615-xcz8m9a7	196	4	.	.	.
cord-009615-xcz8m9a7	197	1	The	the	DT
cord-009615-xcz8m9a7	197	2	polyomaviruses	polyomaviruse	NNS
cord-009615-xcz8m9a7	197	3	are	be	VBP
cord-009615-xcz8m9a7	197	4	involved	involve	VBN
cord-009615-xcz8m9a7	197	5	not	not	RB
cord-009615-xcz8m9a7	197	6	only	only	RB
cord-009615-xcz8m9a7	197	7	in	in	IN
cord-009615-xcz8m9a7	197	8	demyelinating	demyelinating	JJ
cord-009615-xcz8m9a7	197	9	disease	disease	NN
cord-009615-xcz8m9a7	197	10	,	,	,
cord-009615-xcz8m9a7	197	11	but	but	CC
cord-009615-xcz8m9a7	197	12	are	be	VBP
cord-009615-xcz8m9a7	197	13	best	well	RBS
cord-009615-xcz8m9a7	197	14	known	know	VBN
cord-009615-xcz8m9a7	197	15	as	as	IN
cord-009615-xcz8m9a7	197	16	DNA	dna	NN
cord-009615-xcz8m9a7	197	17	tumor	tumor	NN
cord-009615-xcz8m9a7	197	18	viruses	virus	NNS
cord-009615-xcz8m9a7	197	19	in	in	IN
cord-009615-xcz8m9a7	197	20	animal	animal	NN
cord-009615-xcz8m9a7	197	21	models	model	NNS
cord-009615-xcz8m9a7	197	22	.	.	.
cord-009615-xcz8m9a7	198	1	This	this	DT
cord-009615-xcz8m9a7	198	2	has	have	VBZ
cord-009615-xcz8m9a7	198	3	encouraged	encourage	VBN
cord-009615-xcz8m9a7	198	4	a	a	DT
cord-009615-xcz8m9a7	198	5	continuing	continue	VBG
cord-009615-xcz8m9a7	198	6	search	search	NN
cord-009615-xcz8m9a7	198	7	for	for	IN
cord-009615-xcz8m9a7	198	8	these	these	DT
cord-009615-xcz8m9a7	198	9	viruses	virus	NNS
cord-009615-xcz8m9a7	198	10	in	in	IN
cord-009615-xcz8m9a7	198	11	human	human	JJ
cord-009615-xcz8m9a7	198	12	tumors	tumor	NNS
cord-009615-xcz8m9a7	198	13	(	(	-LRB-
cord-009615-xcz8m9a7	198	14	73	73	CD
cord-009615-xcz8m9a7	198	15	)	)	-RRB-
cord-009615-xcz8m9a7	198	16	.	.	.
cord-009615-xcz8m9a7	199	1	Thus	thus	RB
cord-009615-xcz8m9a7	199	2	,	,	,
cord-009615-xcz8m9a7	199	3	three	three	CD
cord-009615-xcz8m9a7	199	4	possible	possible	JJ
cord-009615-xcz8m9a7	199	5	outcomes	outcome	NNS
cord-009615-xcz8m9a7	199	6	of	of	IN
cord-009615-xcz8m9a7	199	7	JCV	JCV	NNP
cord-009615-xcz8m9a7	199	8	latency	latency	NN
cord-009615-xcz8m9a7	199	9	in	in	IN
cord-009615-xcz8m9a7	199	10	the	the	DT
cord-009615-xcz8m9a7	199	11	human	human	JJ
cord-009615-xcz8m9a7	199	12	brain	brain	NN
cord-009615-xcz8m9a7	199	13	can	can	MD
cord-009615-xcz8m9a7	199	14	be	be	VB
cord-009615-xcz8m9a7	199	15	envisioned	envision	VBN
cord-009615-xcz8m9a7	199	16	(	(	-LRB-
cord-009615-xcz8m9a7	199	17	see	see	VB
cord-009615-xcz8m9a7	199	18	Fig	Fig	NNP
cord-009615-xcz8m9a7	199	19	.	.	NNP
cord-009615-xcz8m9a7	199	20	4	4	CD
cord-009615-xcz8m9a7	199	21	)	)	-RRB-
cord-009615-xcz8m9a7	199	22	.	.	.
cord-009615-xcz8m9a7	200	1	The	the	DT
cord-009615-xcz8m9a7	200	2	etiological	etiological	JJ
cord-009615-xcz8m9a7	200	3	role	role	NN
cord-009615-xcz8m9a7	200	4	of	of	IN
cord-009615-xcz8m9a7	200	5	JCV	JCV	NNP
cord-009615-xcz8m9a7	200	6	in	in	IN
cord-009615-xcz8m9a7	200	7	PML	PML	NNP
cord-009615-xcz8m9a7	200	8	is	be	VBZ
cord-009615-xcz8m9a7	200	9	well	well	RB
cord-009615-xcz8m9a7	200	10	established	establish	VBN
cord-009615-xcz8m9a7	200	11	,	,	,
cord-009615-xcz8m9a7	200	12	but	but	CC
cord-009615-xcz8m9a7	200	13	the	the	DT
cord-009615-xcz8m9a7	200	14	other	other	JJ
cord-009615-xcz8m9a7	200	15	outcomes	outcome	NNS
cord-009615-xcz8m9a7	200	16	(	(	-LRB-
cord-009615-xcz8m9a7	200	17	Figs	fig	NNS
cord-009615-xcz8m9a7	200	18	.	.	.
cord-009615-xcz8m9a7	200	19	4c,4d	4c,4d	NNP
cord-009615-xcz8m9a7	200	20	)	)	-RRB-
cord-009615-xcz8m9a7	200	21	remain	remain	VBP
cord-009615-xcz8m9a7	200	22	speculative	speculative	JJ
cord-009615-xcz8m9a7	200	23	.	.	.
cord-009615-xcz8m9a7	201	1	With	with	IN
cord-009615-xcz8m9a7	201	2	respect	respect	NN
cord-009615-xcz8m9a7	201	3	to	to	IN
cord-009615-xcz8m9a7	201	4	tumorigenesis	tumorigenesis	NN
cord-009615-xcz8m9a7	201	5	by	by	IN
cord-009615-xcz8m9a7	201	6	JCV	JCV	NNP
cord-009615-xcz8m9a7	201	7	,	,	,
cord-009615-xcz8m9a7	201	8	interest	interest	NN
cord-009615-xcz8m9a7	201	9	has	have	VBZ
cord-009615-xcz8m9a7	201	10	centered	center	VBN
cord-009615-xcz8m9a7	201	11	around	around	IN
cord-009615-xcz8m9a7	201	12	medulloblastomas	medulloblastomas	NNP
cord-009615-xcz8m9a7	201	13	(	(	-LRB-
cord-009615-xcz8m9a7	201	14	67	67	CD
cord-009615-xcz8m9a7	201	15	,	,	,
cord-009615-xcz8m9a7	201	16	127	127	CD
cord-009615-xcz8m9a7	201	17	,	,	,
cord-009615-xcz8m9a7	201	18	159	159	CD
cord-009615-xcz8m9a7	201	19	,	,	,
cord-009615-xcz8m9a7	201	20	160	160	CD
cord-009615-xcz8m9a7	201	21	)	)	-RRB-
cord-009615-xcz8m9a7	201	22	,	,	,
cord-009615-xcz8m9a7	201	23	but	but	CC
cord-009615-xcz8m9a7	201	24	there	there	EX
cord-009615-xcz8m9a7	201	25	is	be	VBZ
cord-009615-xcz8m9a7	201	26	currently	currently	RB
cord-009615-xcz8m9a7	201	27	no	no	DT
cord-009615-xcz8m9a7	201	28	direct	direct	JJ
cord-009615-xcz8m9a7	201	29	evidence	evidence	NN
cord-009615-xcz8m9a7	201	30	for	for	IN
cord-009615-xcz8m9a7	201	31	involvement	involvement	NN
cord-009615-xcz8m9a7	201	32	of	of	IN
cord-009615-xcz8m9a7	201	33	JCV	JCV	NNP
cord-009615-xcz8m9a7	201	34	in	in	IN
cord-009615-xcz8m9a7	201	35	human	human	JJ
cord-009615-xcz8m9a7	201	36	tumors	tumor	NNS
cord-009615-xcz8m9a7	201	37	.	.	.
cord-009615-xcz8m9a7	202	1	However	however	RB
cord-009615-xcz8m9a7	202	2	,	,	,
cord-009615-xcz8m9a7	202	3	from	from	IN
cord-009615-xcz8m9a7	202	4	this	this	DT
cord-009615-xcz8m9a7	202	5	perspective	perspective	NN
cord-009615-xcz8m9a7	202	6	the	the	DT
cord-009615-xcz8m9a7	202	7	unexplained	unexplained	JJ
cord-009615-xcz8m9a7	202	8	reports	report	NNS
cord-009615-xcz8m9a7	202	9	of	of	IN
cord-009615-xcz8m9a7	202	10	MS	MS	NNP
cord-009615-xcz8m9a7	202	11	lesions	lesion	NNS
cord-009615-xcz8m9a7	202	12	and	and	CC
cord-009615-xcz8m9a7	202	13	gliomas	gliomas	RB
cord-009615-xcz8m9a7	202	14	occupying	occupy	VBG
cord-009615-xcz8m9a7	202	15	the	the	DT
cord-009615-xcz8m9a7	202	16	same	same	JJ
cord-009615-xcz8m9a7	202	17	anatomical	anatomical	JJ
cord-009615-xcz8m9a7	202	18	locations	location	NNS
cord-009615-xcz8m9a7	202	19	(	(	-LRB-
cord-009615-xcz8m9a7	202	20	161	161	CD
cord-009615-xcz8m9a7	202	21	-	-	SYM
cord-009615-xcz8m9a7	202	22	166	166	CD
cord-009615-xcz8m9a7	202	23	)	)	-RRB-
cord-009615-xcz8m9a7	202	24	may	may	MD
cord-009615-xcz8m9a7	202	25	not	not	RB
cord-009615-xcz8m9a7	202	26	be	be	VB
cord-009615-xcz8m9a7	202	27	chance	chance	NN
cord-009615-xcz8m9a7	202	28	occurrences	occurrence	NNS
cord-009615-xcz8m9a7	202	29	.	.	.
cord-009615-xcz8m9a7	203	1	Reports	report	NNS
cord-009615-xcz8m9a7	203	2	that	that	IN
cord-009615-xcz8m9a7	203	3	PML	PML	NNP
cord-009615-xcz8m9a7	203	4	and	and	CC
cord-009615-xcz8m9a7	203	5	multiple	multiple	JJ
cord-009615-xcz8m9a7	203	6	gliomas	glioma	NNS
cord-009615-xcz8m9a7	203	7	(	(	-LRB-
cord-009615-xcz8m9a7	203	8	167	167	CD
cord-009615-xcz8m9a7	203	9	)	)	-RRB-
cord-009615-xcz8m9a7	203	10	or	or	CC
cord-009615-xcz8m9a7	203	11	astrocytomas	astrocytomas	NNPS
cord-009615-xcz8m9a7	203	12	(	(	-LRB-
cord-009615-xcz8m9a7	203	13	168	168	CD
cord-009615-xcz8m9a7	203	14	)	)	-RRB-
cord-009615-xcz8m9a7	203	15	can	can	MD
cord-009615-xcz8m9a7	203	16	coincide	coincide	VB
cord-009615-xcz8m9a7	203	17	are	be	VBP
cord-009615-xcz8m9a7	203	18	also	also	RB
cord-009615-xcz8m9a7	203	19	of	of	IN
cord-009615-xcz8m9a7	203	20	interest	interest	NN
cord-009615-xcz8m9a7	203	21	in	in	IN
cord-009615-xcz8m9a7	203	22	this	this	DT
cord-009615-xcz8m9a7	203	23	context	context	NN
cord-009615-xcz8m9a7	203	24	.	.	.
cord-009615-xcz8m9a7	204	1	Finally	finally	RB
cord-009615-xcz8m9a7	204	2	,	,	,
cord-009615-xcz8m9a7	204	3	the	the	DT
cord-009615-xcz8m9a7	204	4	coincidence	coincidence	NN
cord-009615-xcz8m9a7	204	5	of	of	IN
cord-009615-xcz8m9a7	204	6	clinical	clinical	JJ
cord-009615-xcz8m9a7	204	7	MS	MS	NNP
cord-009615-xcz8m9a7	204	8	and	and	CC
cord-009615-xcz8m9a7	204	9	PML	PML	NNP
cord-009615-xcz8m9a7	204	10	(	(	-LRB-
cord-009615-xcz8m9a7	204	11	169,170	169,170	CD
cord-009615-xcz8m9a7	204	12	)	)	-RRB-
cord-009615-xcz8m9a7	204	13	completes	complete	VBZ
cord-009615-xcz8m9a7	204	14	the	the	DT
cord-009615-xcz8m9a7	204	15	reported	report	VBN
cord-009615-xcz8m9a7	204	16	associations	association	NNS
cord-009615-xcz8m9a7	204	17	between	between	IN
cord-009615-xcz8m9a7	204	18	these	these	DT
cord-009615-xcz8m9a7	204	19	three	three	CD
cord-009615-xcz8m9a7	204	20	different	different	JJ
cord-009615-xcz8m9a7	204	21	outcomes	outcome	NNS
cord-009615-xcz8m9a7	204	22	.	.	.
cord-009615-xcz8m9a7	205	1	This	this	DT
cord-009615-xcz8m9a7	205	2	latter	latter	JJ
cord-009615-xcz8m9a7	205	3	association	association	NN
cord-009615-xcz8m9a7	205	4	occurred	occur	VBD
cord-009615-xcz8m9a7	205	5	before	before	IN
cord-009615-xcz8m9a7	205	6	the	the	DT
cord-009615-xcz8m9a7	205	7	AIDS	AIDS	NNP
cord-009615-xcz8m9a7	205	8	epidemic	epidemic	NN
cord-009615-xcz8m9a7	205	9	under	under	IN
cord-009615-xcz8m9a7	205	10	the	the	DT
cord-009615-xcz8m9a7	205	11	combined	combine	VBN
cord-009615-xcz8m9a7	205	12	influence	influence	NN
cord-009615-xcz8m9a7	205	13	of	of	IN
cord-009615-xcz8m9a7	205	14	systemic	systemic	JJ
cord-009615-xcz8m9a7	205	15	lupus	lupus	NN
cord-009615-xcz8m9a7	205	16	erythematosus	erythematosus	NN
cord-009615-xcz8m9a7	205	17	(	(	-LRB-
cord-009615-xcz8m9a7	205	18	SLE	SLE	NNP
cord-009615-xcz8m9a7	205	19	)	)	-RRB-
cord-009615-xcz8m9a7	205	20	and	and	CC
cord-009615-xcz8m9a7	205	21	corticosteroid	corticosteroid	NN
cord-009615-xcz8m9a7	205	22	therapy	therapy	NN
cord-009615-xcz8m9a7	205	23	(	(	-LRB-
cord-009615-xcz8m9a7	205	24	170	170	CD
cord-009615-xcz8m9a7	205	25	)	)	-RRB-
cord-009615-xcz8m9a7	205	26	.	.	.
cord-009615-xcz8m9a7	206	1	It	-PRON-	PRP
cord-009615-xcz8m9a7	206	2	is	be	VBZ
cord-009615-xcz8m9a7	206	3	not	not	RB
cord-009615-xcz8m9a7	206	4	certain	certain	JJ
cord-009615-xcz8m9a7	206	5	that	that	IN
cord-009615-xcz8m9a7	206	6	this	this	DT
cord-009615-xcz8m9a7	206	7	was	be	VBD
cord-009615-xcz8m9a7	206	8	a	a	DT
cord-009615-xcz8m9a7	206	9	case	case	NN
cord-009615-xcz8m9a7	206	10	of	of	IN
cord-009615-xcz8m9a7	206	11	MS	MS	NNP
cord-009615-xcz8m9a7	206	12	as	as	IN
cord-009615-xcz8m9a7	206	13	the	the	DT
cord-009615-xcz8m9a7	206	14	demyelinated	demyelinate	VBN
cord-009615-xcz8m9a7	206	15	lesions	lesion	NNS
cord-009615-xcz8m9a7	206	16	observed	observe	VBD
cord-009615-xcz8m9a7	206	17	at	at	IN
cord-009615-xcz8m9a7	206	18	autopsy	autopsy	NN
cord-009615-xcz8m9a7	206	19	could	could	MD
cord-009615-xcz8m9a7	206	20	not	not	RB
cord-009615-xcz8m9a7	206	21	be	be	VB
cord-009615-xcz8m9a7	206	22	distinguished	distinguish	VBN
cord-009615-xcz8m9a7	206	23	from	from	IN
cord-009615-xcz8m9a7	206	24	those	those	DT
cord-009615-xcz8m9a7	206	25	of	of	IN
cord-009615-xcz8m9a7	206	26	chronic	chronic	JJ
cord-009615-xcz8m9a7	206	27	PML	PML	NNP
cord-009615-xcz8m9a7	206	28	(	(	-LRB-
cord-009615-xcz8m9a7	206	29	171	171	CD
cord-009615-xcz8m9a7	206	30	)	)	-RRB-
cord-009615-xcz8m9a7	206	31	.	.	.
cord-009615-xcz8m9a7	207	1	A	a	DT
cord-009615-xcz8m9a7	207	2	latent	latent	JJ
cord-009615-xcz8m9a7	207	3	virus	virus	NN
cord-009615-xcz8m9a7	207	4	distributed	distribute	VBN
cord-009615-xcz8m9a7	207	5	multifocally	multifocally	RB
cord-009615-xcz8m9a7	207	6	in	in	IN
cord-009615-xcz8m9a7	207	7	the	the	DT
cord-009615-xcz8m9a7	207	8	CNS	CNS	NNP
cord-009615-xcz8m9a7	207	9	with	with	IN
cord-009615-xcz8m9a7	207	10	its	-PRON-	PRP$
cord-009615-xcz8m9a7	207	11	expression	expression	NN
cord-009615-xcz8m9a7	207	12	modulated	modulate	VBN
cord-009615-xcz8m9a7	207	13	by	by	IN
cord-009615-xcz8m9a7	207	14	the	the	DT
cord-009615-xcz8m9a7	207	15	immune	immune	JJ
cord-009615-xcz8m9a7	207	16	response	response	NN
cord-009615-xcz8m9a7	207	17	as	as	RB
cord-009615-xcz8m9a7	207	18	well	well	RB
cord-009615-xcz8m9a7	207	19	as	as	IN
cord-009615-xcz8m9a7	207	20	by	by	IN
cord-009615-xcz8m9a7	207	21	transactivating	transactivating	NN
cord-009615-xcz8m9a7	207	22	factors	factor	NNS
cord-009615-xcz8m9a7	207	23	acting	act	VBG
cord-009615-xcz8m9a7	207	24	within	within	IN
cord-009615-xcz8m9a7	207	25	or	or	CC
cord-009615-xcz8m9a7	207	26	between	between	IN
cord-009615-xcz8m9a7	207	27	cells	cell	NNS
cord-009615-xcz8m9a7	207	28	,	,	,
cord-009615-xcz8m9a7	207	29	could	could	MD
cord-009615-xcz8m9a7	207	30	explain	explain	VB
cord-009615-xcz8m9a7	207	31	the	the	DT
cord-009615-xcz8m9a7	207	32	varied	varied	JJ
cord-009615-xcz8m9a7	207	33	clinical	clinical	JJ
cord-009615-xcz8m9a7	207	34	course	course	NN
cord-009615-xcz8m9a7	207	35	of	of	IN
cord-009615-xcz8m9a7	207	36	MS	MS	NNP
cord-009615-xcz8m9a7	207	37	.	.	.
cord-009615-xcz8m9a7	208	1	In	in	IN
cord-009615-xcz8m9a7	208	2	view	view	NN
cord-009615-xcz8m9a7	208	3	of	of	IN
cord-009615-xcz8m9a7	208	4	the	the	DT
cord-009615-xcz8m9a7	208	5	evidence	evidence	NN
cord-009615-xcz8m9a7	208	6	for	for	IN
cord-009615-xcz8m9a7	208	7	their	-PRON-	PRP$
cord-009615-xcz8m9a7	208	8	presence	presence	NN
cord-009615-xcz8m9a7	208	9	in	in	IN
cord-009615-xcz8m9a7	208	10	normal	normal	JJ
cord-009615-xcz8m9a7	208	11	brain	brain	NN
cord-009615-xcz8m9a7	208	12	,	,	,
cord-009615-xcz8m9a7	208	13	the	the	DT
cord-009615-xcz8m9a7	208	14	small	small	JJ
cord-009615-xcz8m9a7	208	15	human	human	JJ
cord-009615-xcz8m9a7	208	16	DNA	dna	NN
cord-009615-xcz8m9a7	208	17	viruses	virus	NNS
cord-009615-xcz8m9a7	208	18	with	with	IN
cord-009615-xcz8m9a7	208	19	gliotropic	gliotropic	NNP
cord-009615-xcz8m9a7	208	20	properties	property	NNS
cord-009615-xcz8m9a7	208	21	provide	provide	VBP
cord-009615-xcz8m9a7	208	22	a	a	DT
cord-009615-xcz8m9a7	208	23	compelling	compelling	JJ
cord-009615-xcz8m9a7	208	24	argument	argument	NN
cord-009615-xcz8m9a7	208	25	for	for	IN
cord-009615-xcz8m9a7	208	26	a	a	DT
cord-009615-xcz8m9a7	208	27	disease	disease	NN
cord-009615-xcz8m9a7	208	28	mechanism	mechanism	NN
cord-009615-xcz8m9a7	208	29	in	in	IN
cord-009615-xcz8m9a7	208	30	which	which	WDT
cord-009615-xcz8m9a7	208	31	a	a	DT
cord-009615-xcz8m9a7	208	32	common	common	JJ
cord-009615-xcz8m9a7	208	33	virus	virus	NN
cord-009615-xcz8m9a7	208	34	latent	latent	VBN
cord-009615-xcz8m9a7	208	35	in	in	IN
cord-009615-xcz8m9a7	208	36	CNS	CNS	NNP
cord-009615-xcz8m9a7	208	37	white	white	JJ
cord-009615-xcz8m9a7	208	38	matter	matter	NN
cord-009615-xcz8m9a7	208	39	provokes	provoke	VBZ
cord-009615-xcz8m9a7	208	40	an	an	DT
cord-009615-xcz8m9a7	208	41	uncommon	uncommon	JJ
cord-009615-xcz8m9a7	208	42	immunopathological	immunopathological	JJ
cord-009615-xcz8m9a7	208	43	response	response	NN
cord-009615-xcz8m9a7	208	44	in	in	IN
cord-009615-xcz8m9a7	208	45	a	a	DT
cord-009615-xcz8m9a7	208	46	few	few	JJ
cord-009615-xcz8m9a7	208	47	susceptible	susceptible	JJ
cord-009615-xcz8m9a7	208	48	individuals	individual	NNS
cord-009615-xcz8m9a7	208	49	.	.	.
cord-009615-xcz8m9a7	209	1	Along	along	IN
cord-009615-xcz8m9a7	209	2	with	with	IN
cord-009615-xcz8m9a7	209	3	the	the	DT
cord-009615-xcz8m9a7	209	4	recent	recent	JJ
cord-009615-xcz8m9a7	209	5	evidence	evidence	NN
cord-009615-xcz8m9a7	209	6	for	for	IN
cord-009615-xcz8m9a7	209	7	coronavirus	coronavirus	NN
cord-009615-xcz8m9a7	209	8	sequences	sequence	NNS
cord-009615-xcz8m9a7	209	9	in	in	IN
cord-009615-xcz8m9a7	209	10	MS	MS	NNP
cord-009615-xcz8m9a7	209	11	brains	brain	NNS
cord-009615-xcz8m9a7	209	12	(	(	-LRB-
cord-009615-xcz8m9a7	209	13	42,43	42,43	CD
cord-009615-xcz8m9a7	209	14	)	)	-RRB-
cord-009615-xcz8m9a7	209	15	,	,	,
cord-009615-xcz8m9a7	209	16	these	these	DT
cord-009615-xcz8m9a7	209	17	polyomavirus	polyomavirus	NNP
cord-009615-xcz8m9a7	209	18	findings	finding	NNS
cord-009615-xcz8m9a7	209	19	emphasize	emphasize	VBP
cord-009615-xcz8m9a7	209	20	the	the	DT
cord-009615-xcz8m9a7	209	21	relevance	relevance	NN
cord-009615-xcz8m9a7	209	22	of	of	IN
cord-009615-xcz8m9a7	209	23	the	the	DT
cord-009615-xcz8m9a7	209	24	latent	latent	JJ
cord-009615-xcz8m9a7	209	25	-	-	HYPH
cord-009615-xcz8m9a7	209	26	virus	virus	NN
cord-009615-xcz8m9a7	209	27	model	model	NN
cord-009615-xcz8m9a7	209	28	to	to	IN
cord-009615-xcz8m9a7	209	29	demyelinating	demyelinating	JJ
cord-009615-xcz8m9a7	209	30	disease	disease	NN
cord-009615-xcz8m9a7	209	31	.	.	.
cord-009615-xcz8m9a7	210	1	Virus	virus	NN
cord-009615-xcz8m9a7	210	2	latency	latency	NN
cord-009615-xcz8m9a7	210	3	in	in	IN
cord-009615-xcz8m9a7	210	4	the	the	DT
cord-009615-xcz8m9a7	210	5	CNS	CNS	NNP
cord-009615-xcz8m9a7	210	6	couid	couid	NNS
cord-009615-xcz8m9a7	210	7	be	be	VBP
cord-009615-xcz8m9a7	210	8	the	the	DT
cord-009615-xcz8m9a7	210	9	essential	essential	JJ
cord-009615-xcz8m9a7	210	10	precondition	precondition	NN
cord-009615-xcz8m9a7	210	11	for	for	IN
cord-009615-xcz8m9a7	210	12	onset	onset	NN
cord-009615-xcz8m9a7	210	13	of	of	IN
cord-009615-xcz8m9a7	210	14	MS	MS	NNP
cord-009615-xcz8m9a7	210	15	pathology	pathology	NN
cord-009615-xcz8m9a7	210	16	,	,	,
cord-009615-xcz8m9a7	210	17	i.e.	i.e.	FW
cord-009615-xcz8m9a7	210	18	,	,	,
cord-009615-xcz8m9a7	210	19	the	the	DT
cord-009615-xcz8m9a7	210	20	so	so	RB
cord-009615-xcz8m9a7	210	21	-	-	HYPH
cord-009615-xcz8m9a7	210	22	called	call	VBN
cord-009615-xcz8m9a7	210	23	"	"	``
cord-009615-xcz8m9a7	210	24	MS	MS	NNP
cord-009615-xcz8m9a7	210	25	trait	trait	NN
cord-009615-xcz8m9a7	210	26	"	"	''
cord-009615-xcz8m9a7	210	27	(	(	-LRB-
cord-009615-xcz8m9a7	210	28	172	172	CD
cord-009615-xcz8m9a7	210	29	)	)	-RRB-
cord-009615-xcz8m9a7	210	30	.	.	.
cord-009615-xcz8m9a7	211	1	AIthough	AIthough	NNP
cord-009615-xcz8m9a7	212	1	the	the	DT
cord-009615-xcz8m9a7	212	2	number	number	NN
cord-009615-xcz8m9a7	212	3	of	of	IN
cord-009615-xcz8m9a7	212	4	different	different	JJ
cord-009615-xcz8m9a7	212	5	viruses	virus	NNS
cord-009615-xcz8m9a7	212	6	which	which	WDT
cord-009615-xcz8m9a7	212	7	may	may	MD
cord-009615-xcz8m9a7	212	8	eventually	eventually	RB
cord-009615-xcz8m9a7	212	9	be	be	VB
cord-009615-xcz8m9a7	212	10	implicated	implicate	VBN
cord-009615-xcz8m9a7	212	11	in	in	IN
cord-009615-xcz8m9a7	212	12	CNS	CNS	NNP
cord-009615-xcz8m9a7	212	13	latency	latency	NN
cord-009615-xcz8m9a7	212	14	remains	remain	VBZ
cord-009615-xcz8m9a7	212	15	unclear	unclear	JJ
cord-009615-xcz8m9a7	212	16	,	,	,
cord-009615-xcz8m9a7	212	17	it	-PRON-	PRP
cord-009615-xcz8m9a7	212	18	is	be	VBZ
cord-009615-xcz8m9a7	212	19	apparent	apparent	JJ
cord-009615-xcz8m9a7	212	20	that	that	IN
cord-009615-xcz8m9a7	212	21	the	the	DT
cord-009615-xcz8m9a7	212	22	immune	immune	JJ
cord-009615-xcz8m9a7	212	23	response	response	NN
cord-009615-xcz8m9a7	212	24	to	to	IN
cord-009615-xcz8m9a7	212	25	a	a	DT
cord-009615-xcz8m9a7	212	26	single	single	JJ
cord-009615-xcz8m9a7	212	27	virus	virus	NN
cord-009615-xcz8m9a7	212	28	in	in	IN
cord-009615-xcz8m9a7	212	29	the	the	DT
cord-009615-xcz8m9a7	212	30	CNS	CNS	NNP
cord-009615-xcz8m9a7	212	31	could	could	MD
cord-009615-xcz8m9a7	212	32	provoke	provoke	VB
cord-009615-xcz8m9a7	212	33	a	a	DT
cord-009615-xcz8m9a7	212	34	disease	disease	NN
cord-009615-xcz8m9a7	212	35	as	as	RB
cord-009615-xcz8m9a7	212	36	diverse	diverse	JJ
cord-009615-xcz8m9a7	212	37	and	and	CC
cord-009615-xcz8m9a7	212	38	variable	variable	JJ
cord-009615-xcz8m9a7	212	39	in	in	IN
cord-009615-xcz8m9a7	212	40	its	-PRON-	PRP$
cord-009615-xcz8m9a7	212	41	expression	expression	NN
cord-009615-xcz8m9a7	212	42	as	as	IN
cord-009615-xcz8m9a7	212	43	MS	MS	NNP
cord-009615-xcz8m9a7	212	44	.	.	.
cord-009615-xcz8m9a7	213	1	The	the	DT
cord-009615-xcz8m9a7	213	2	interplay	interplay	NN
cord-009615-xcz8m9a7	213	3	of	of	IN
cord-009615-xcz8m9a7	213	4	the	the	DT
cord-009615-xcz8m9a7	213	5	genetic	genetic	JJ
cord-009615-xcz8m9a7	213	6	and	and	CC
cord-009615-xcz8m9a7	213	7	environmental	environmental	JJ
cord-009615-xcz8m9a7	213	8	factors	factor	NNS
cord-009615-xcz8m9a7	213	9	listed	list	VBN
cord-009615-xcz8m9a7	213	10	above	above	IN
cord-009615-xcz8m9a7	213	11	acting	act	VBG
cord-009615-xcz8m9a7	213	12	on	on	IN
cord-009615-xcz8m9a7	213	13	a	a	DT
cord-009615-xcz8m9a7	213	14	viral	viral	JJ
cord-009615-xcz8m9a7	213	15	infection	infection	NN
cord-009615-xcz8m9a7	213	16	capable	capable	JJ
cord-009615-xcz8m9a7	213	17	of	of	IN
cord-009615-xcz8m9a7	213	18	latency	latency	NN
cord-009615-xcz8m9a7	213	19	and	and	CC
cord-009615-xcz8m9a7	213	20	reactivation	reactivation	NN
cord-009615-xcz8m9a7	213	21	could	could	MD
cord-009615-xcz8m9a7	213	22	explain	explain	VB
cord-009615-xcz8m9a7	213	23	the	the	DT
cord-009615-xcz8m9a7	213	24	complex	complex	JJ
cord-009615-xcz8m9a7	213	25	and	and	CC
cord-009615-xcz8m9a7	213	26	unpredictable	unpredictable	JJ
cord-009615-xcz8m9a7	213	27	clinical	clinical	JJ
cord-009615-xcz8m9a7	213	28	course	course	NN
cord-009615-xcz8m9a7	213	29	of	of	IN
cord-009615-xcz8m9a7	213	30	MS	MS	NNP
cord-009615-xcz8m9a7	213	31	as	as	RB
cord-009615-xcz8m9a7	213	32	well	well	RB
cord-009615-xcz8m9a7	213	33	as	as	IN
cord-009615-xcz8m9a7	213	34	does	do	VBZ
cord-009615-xcz8m9a7	213	35	the	the	DT
cord-009615-xcz8m9a7	213	36	CR	CR	NNP
cord-009615-xcz8m9a7	213	37	-	-	HYPH
cord-009615-xcz8m9a7	213	38	EAE	EAE	NNP
cord-009615-xcz8m9a7	213	39	model	model	NN
cord-009615-xcz8m9a7	213	40	.	.	.
cord-009615-xcz8m9a7	214	1	The	the	DT
cord-009615-xcz8m9a7	214	2	latent	latent	JJ
cord-009615-xcz8m9a7	214	3	-	-	HYPH
cord-009615-xcz8m9a7	214	4	virus	virus	NN
cord-009615-xcz8m9a7	214	5	model	model	NN
cord-009615-xcz8m9a7	214	6	of	of	IN
cord-009615-xcz8m9a7	214	7	MS	MS	NNP
cord-009615-xcz8m9a7	214	8	pathogenesis	pathogenesis	NN
cord-009615-xcz8m9a7	214	9	has	have	VBZ
cord-009615-xcz8m9a7	214	10	several	several	JJ
cord-009615-xcz8m9a7	214	11	conceptual	conceptual	JJ
cord-009615-xcz8m9a7	214	12	advantages	advantage	NNS
cord-009615-xcz8m9a7	214	13	:	:	:
cord-009615-xcz8m9a7	214	14	1	1	LS
cord-009615-xcz8m9a7	214	15	)	)	-RRB-
cord-009615-xcz8m9a7	214	16	Provides	provide	VBZ
cord-009615-xcz8m9a7	214	17	a	a	DT
cord-009615-xcz8m9a7	214	18	mechanism	mechanism	NN
cord-009615-xcz8m9a7	214	19	for	for	IN
cord-009615-xcz8m9a7	214	20	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	214	21	distribution	distribution	NN
cord-009615-xcz8m9a7	214	22	of	of	IN
cord-009615-xcz8m9a7	214	23	antigen	antigen	NN
cord-009615-xcz8m9a7	214	24	in	in	IN
cord-009615-xcz8m9a7	214	25	the	the	DT
cord-009615-xcz8m9a7	214	26	CNS	CNS	NNP
cord-009615-xcz8m9a7	214	27	without	without	IN
cord-009615-xcz8m9a7	214	28	requiring	require	VBG
cord-009615-xcz8m9a7	214	29	viral	viral	JJ
cord-009615-xcz8m9a7	214	30	replication	replication	NN
cord-009615-xcz8m9a7	214	31	independent	independent	JJ
cord-009615-xcz8m9a7	214	32	of	of	IN
cord-009615-xcz8m9a7	214	33	cell	cell	NN
cord-009615-xcz8m9a7	214	34	division	division	NN
cord-009615-xcz8m9a7	214	35	,	,	,
cord-009615-xcz8m9a7	214	36	if	if	IN
cord-009615-xcz8m9a7	214	37	the	the	DT
cord-009615-xcz8m9a7	214	38	infection	infection	NN
cord-009615-xcz8m9a7	214	39	occurs	occur	VBZ
cord-009615-xcz8m9a7	214	40	early	early	RB
cord-009615-xcz8m9a7	214	41	in	in	IN
cord-009615-xcz8m9a7	214	42	life	life	NN
cord-009615-xcz8m9a7	214	43	;	;	:
cord-009615-xcz8m9a7	214	44	2	2	LS
cord-009615-xcz8m9a7	214	45	)	)	-RRB-
cord-009615-xcz8m9a7	214	46	Allows	allow	VBZ
cord-009615-xcz8m9a7	214	47	for	for	IN
cord-009615-xcz8m9a7	214	48	regulated	regulate	VBN
cord-009615-xcz8m9a7	214	49	antigen	antigen	NN
cord-009615-xcz8m9a7	214	50	expression	expression	NN
cord-009615-xcz8m9a7	214	51	,	,	,
cord-009615-xcz8m9a7	214	52	variable	variable	JJ
cord-009615-xcz8m9a7	214	53	in	in	IN
cord-009615-xcz8m9a7	214	54	time	time	NN
cord-009615-xcz8m9a7	214	55	,	,	,
cord-009615-xcz8m9a7	214	56	within	within	IN
cord-009615-xcz8m9a7	214	57	those	those	DT
cord-009615-xcz8m9a7	214	58	foci	foci	NN
cord-009615-xcz8m9a7	214	59	,	,	,
cord-009615-xcz8m9a7	214	60	and	and	CC
cord-009615-xcz8m9a7	214	61	3	3	LS
cord-009615-xcz8m9a7	214	62	)	)	-RRB-
cord-009615-xcz8m9a7	214	63	Has	have	VBZ
cord-009615-xcz8m9a7	214	64	the	the	DT
cord-009615-xcz8m9a7	214	65	potential	potential	NN
cord-009615-xcz8m9a7	214	66	for	for	IN
cord-009615-xcz8m9a7	214	67	modulation	modulation	NN
cord-009615-xcz8m9a7	214	68	of	of	IN
cord-009615-xcz8m9a7	214	69	the	the	DT
cord-009615-xcz8m9a7	214	70	immune	immune	JJ
cord-009615-xcz8m9a7	214	71	response	response	NN
cord-009615-xcz8m9a7	214	72	by	by	IN
cord-009615-xcz8m9a7	214	73	cross	cross	JJ
cord-009615-xcz8m9a7	214	74	-	-	JJ
cord-009615-xcz8m9a7	214	75	reactive	reactive	JJ
cord-009615-xcz8m9a7	214	76	viral	viral	JJ
cord-009615-xcz8m9a7	214	77	antigen	antigen	NN
cord-009615-xcz8m9a7	214	78	in	in	IN
cord-009615-xcz8m9a7	214	79	organs	organ	NNS
cord-009615-xcz8m9a7	214	80	outside	outside	IN
cord-009615-xcz8m9a7	214	81	the	the	DT
cord-009615-xcz8m9a7	214	82	CNS	CNS	NNP
cord-009615-xcz8m9a7	214	83	(	(	-LRB-
cord-009615-xcz8m9a7	215	1	e.g.	e.g.	RB
cord-009615-xcz8m9a7	215	2	,	,	,
cord-009615-xcz8m9a7	215	3	by	by	IN
cord-009615-xcz8m9a7	215	4	anti	anti	JJ
cord-009615-xcz8m9a7	215	5	-	-	NNS
cord-009615-xcz8m9a7	215	6	gens	gen	NNS
cord-009615-xcz8m9a7	215	7	of	of	IN
cord-009615-xcz8m9a7	215	8	BKV	BKV	NNP
cord-009615-xcz8m9a7	215	9	if	if	IN
cord-009615-xcz8m9a7	215	10	the	the	DT
cord-009615-xcz8m9a7	215	11	primary	primary	JJ
cord-009615-xcz8m9a7	215	12	CNS	CNS	NNP
cord-009615-xcz8m9a7	215	13	agent	agent	NN
cord-009615-xcz8m9a7	215	14	were	be	VBD
cord-009615-xcz8m9a7	215	15	JCV	JCV	NNP
cord-009615-xcz8m9a7	215	16	)	)	-RRB-
cord-009615-xcz8m9a7	215	17	.	.	.
cord-009615-xcz8m9a7	216	1	With	with	IN
cord-009615-xcz8m9a7	216	2	the	the	DT
cord-009615-xcz8m9a7	216	3	development	development	NN
cord-009615-xcz8m9a7	216	4	of	of	IN
cord-009615-xcz8m9a7	216	5	highly	highly	RB
cord-009615-xcz8m9a7	216	6	sensitive	sensitive	JJ
cord-009615-xcz8m9a7	216	7	PCR	pcr	NN
cord-009615-xcz8m9a7	216	8	techniques	technique	NNS
cord-009615-xcz8m9a7	216	9	,	,	,
cord-009615-xcz8m9a7	216	10	the	the	DT
cord-009615-xcz8m9a7	216	11	tools	tool	NNS
cord-009615-xcz8m9a7	216	12	to	to	TO
cord-009615-xcz8m9a7	216	13	detect	detect	VB
cord-009615-xcz8m9a7	216	14	MS	MS	NNP
cord-009615-xcz8m9a7	216	15	candidate	candidate	NN
cord-009615-xcz8m9a7	216	16	viruses	virus	NNS
cord-009615-xcz8m9a7	216	17	latent	latent	JJ
cord-009615-xcz8m9a7	216	18	in	in	IN
cord-009615-xcz8m9a7	216	19	the	the	DT
cord-009615-xcz8m9a7	216	20	human	human	JJ
cord-009615-xcz8m9a7	216	21	brain	brain	NN
cord-009615-xcz8m9a7	216	22	are	be	VBP
cord-009615-xcz8m9a7	216	23	in	in	IN
cord-009615-xcz8m9a7	216	24	hand	hand	NN
cord-009615-xcz8m9a7	216	25	.	.	.
cord-009615-xcz8m9a7	217	1	Even	even	RB
cord-009615-xcz8m9a7	217	2	if	if	IN
cord-009615-xcz8m9a7	217	3	many	many	JJ
cord-009615-xcz8m9a7	217	4	latently	latently	RB
cord-009615-xcz8m9a7	217	5	infected	infected	JJ
cord-009615-xcz8m9a7	217	6	cells	cell	NNS
cord-009615-xcz8m9a7	217	7	have	have	VBP
cord-009615-xcz8m9a7	217	8	been	be	VBN
cord-009615-xcz8m9a7	217	9	destroyed	destroy	VBN
cord-009615-xcz8m9a7	217	10	by	by	IN
cord-009615-xcz8m9a7	217	11	the	the	DT
cord-009615-xcz8m9a7	217	12	immune	immune	JJ
cord-009615-xcz8m9a7	217	13	response	response	NN
cord-009615-xcz8m9a7	217	14	in	in	IN
cord-009615-xcz8m9a7	217	15	the	the	DT
cord-009615-xcz8m9a7	217	16	course	course	NN
cord-009615-xcz8m9a7	217	17	of	of	IN
cord-009615-xcz8m9a7	217	18	the	the	DT
cord-009615-xcz8m9a7	217	19	disease	disease	NN
cord-009615-xcz8m9a7	217	20	,	,	,
cord-009615-xcz8m9a7	217	21	some	some	DT
cord-009615-xcz8m9a7	217	22	infected	infected	JJ
cord-009615-xcz8m9a7	217	23	cells	cell	NNS
cord-009615-xcz8m9a7	217	24	which	which	WDT
cord-009615-xcz8m9a7	217	25	express	express	VBP
cord-009615-xcz8m9a7	217	26	little	little	JJ
cord-009615-xcz8m9a7	217	27	or	or	CC
cord-009615-xcz8m9a7	217	28	no	no	DT
cord-009615-xcz8m9a7	217	29	antigen	antigen	NN
cord-009615-xcz8m9a7	217	30	and	and	CC
cord-009615-xcz8m9a7	217	31	therefore	therefore	RB
cord-009615-xcz8m9a7	217	32	escape	escape	VB
cord-009615-xcz8m9a7	217	33	destruction	destruction	NN
cord-009615-xcz8m9a7	217	34	may	may	MD
cord-009615-xcz8m9a7	217	35	continue	continue	VB
cord-009615-xcz8m9a7	217	36	to	to	TO
cord-009615-xcz8m9a7	217	37	harbor	harbor	VB
cord-009615-xcz8m9a7	217	38	detectable	detectable	JJ
cord-009615-xcz8m9a7	217	39	levels	level	NNS
cord-009615-xcz8m9a7	217	40	of	of	IN
cord-009615-xcz8m9a7	217	41	viral	viral	JJ
cord-009615-xcz8m9a7	217	42	DNA	dna	NN
cord-009615-xcz8m9a7	217	43	.	.	.
cord-009615-xcz8m9a7	218	1	The	the	DT
cord-009615-xcz8m9a7	218	2	choice	choice	NN
cord-009615-xcz8m9a7	218	3	of	of	IN
cord-009615-xcz8m9a7	218	4	paradigm	paradigm	NN
cord-009615-xcz8m9a7	218	5	is	be	VBZ
cord-009615-xcz8m9a7	218	6	important	important	JJ
cord-009615-xcz8m9a7	218	7	because	because	IN
cord-009615-xcz8m9a7	218	8	it	-PRON-	PRP
cord-009615-xcz8m9a7	218	9	determines	determine	VBZ
cord-009615-xcz8m9a7	218	10	the	the	DT
cord-009615-xcz8m9a7	218	11	range	range	NN
cord-009615-xcz8m9a7	218	12	of	of	IN
cord-009615-xcz8m9a7	218	13	questions	question	NNS
cord-009615-xcz8m9a7	218	14	asked	ask	VBD
cord-009615-xcz8m9a7	218	15	,	,	,
cord-009615-xcz8m9a7	218	16	and	and	CC
cord-009615-xcz8m9a7	218	17	can	can	MD
cord-009615-xcz8m9a7	218	18	,	,	,
cord-009615-xcz8m9a7	218	19	in	in	IN
cord-009615-xcz8m9a7	218	20	turn	turn	NN
cord-009615-xcz8m9a7	218	21	,	,	,
cord-009615-xcz8m9a7	218	22	limit	limit	VB
cord-009615-xcz8m9a7	218	23	the	the	DT
cord-009615-xcz8m9a7	218	24	answers	answer	NNS
cord-009615-xcz8m9a7	218	25	obtained	obtain	VBN
cord-009615-xcz8m9a7	218	26	.	.	.
cord-009615-xcz8m9a7	219	1	Is	be	VBZ
cord-009615-xcz8m9a7	219	2	it	-PRON-	PRP
cord-009615-xcz8m9a7	219	3	time	time	NN
cord-009615-xcz8m9a7	219	4	to	to	TO
cord-009615-xcz8m9a7	219	5	change	change	VB
cord-009615-xcz8m9a7	219	6	the	the	DT
cord-009615-xcz8m9a7	219	7	paradigm	paradigm	NN
cord-009615-xcz8m9a7	219	8	?	?	.
cord-009615-xcz8m9a7	220	1	Within	within	IN
cord-009615-xcz8m9a7	220	2	the	the	DT
cord-009615-xcz8m9a7	220	3	framework	framework	NN
cord-009615-xcz8m9a7	220	4	of	of	IN
cord-009615-xcz8m9a7	220	5	the	the	DT
cord-009615-xcz8m9a7	220	6	EAE	EAE	NNP
cord-009615-xcz8m9a7	220	7	/	/	SYM
cord-009615-xcz8m9a7	220	8	autoimmunity	autoimmunity	NN
cord-009615-xcz8m9a7	220	9	paradigm	paradigm	NN
cord-009615-xcz8m9a7	220	10	have	have	VBP
cord-009615-xcz8m9a7	220	11	come	come	VBN
cord-009615-xcz8m9a7	220	12	significant	significant	JJ
cord-009615-xcz8m9a7	220	13	advances	advance	NNS
cord-009615-xcz8m9a7	220	14	in	in	IN
cord-009615-xcz8m9a7	220	15	our	-PRON-	PRP$
cord-009615-xcz8m9a7	220	16	understanding	understanding	NN
cord-009615-xcz8m9a7	220	17	of	of	IN
cord-009615-xcz8m9a7	220	18	the	the	DT
cord-009615-xcz8m9a7	220	19	pathogenesis	pathogenesis	NN
cord-009615-xcz8m9a7	220	20	of	of	IN
cord-009615-xcz8m9a7	220	21	'	'	''
cord-009615-xcz8m9a7	220	22	MS	MS	NNP
cord-009615-xcz8m9a7	220	23	(	(	-LRB-
cord-009615-xcz8m9a7	220	24	173	173	CD
cord-009615-xcz8m9a7	220	25	,	,	,
cord-009615-xcz8m9a7	220	26	174	174	CD
cord-009615-xcz8m9a7	220	27	)	)	-RRB-
cord-009615-xcz8m9a7	220	28	,	,	,
cord-009615-xcz8m9a7	220	29	and	and	CC
cord-009615-xcz8m9a7	220	30	promising	promise	VBG
cord-009615-xcz8m9a7	220	31	new	new	JJ
cord-009615-xcz8m9a7	220	32	approaches	approach	NNS
cord-009615-xcz8m9a7	220	33	to	to	IN
cord-009615-xcz8m9a7	220	34	treatment	treatment	NN
cord-009615-xcz8m9a7	220	35	(	(	-LRB-
cord-009615-xcz8m9a7	220	36	1	1	CD
cord-009615-xcz8m9a7	220	37	75	75	CD
cord-009615-xcz8m9a7	220	38	-	-	SYM
cord-009615-xcz8m9a7	220	39	177	177	CD
cord-009615-xcz8m9a7	220	40	)	)	-RRB-
cord-009615-xcz8m9a7	220	41	,	,	,
cord-009615-xcz8m9a7	220	42	but	but	CC
cord-009615-xcz8m9a7	220	43	much	much	JJ
cord-009615-xcz8m9a7	220	44	remains	remain	VBZ
cord-009615-xcz8m9a7	220	45	uncertain	uncertain	JJ
cord-009615-xcz8m9a7	220	46	(	(	-LRB-
cord-009615-xcz8m9a7	220	47	4	4	CD
cord-009615-xcz8m9a7	220	48	,	,	,
cord-009615-xcz8m9a7	220	49	178	178	CD
cord-009615-xcz8m9a7	220	50	,	,	,
cord-009615-xcz8m9a7	220	51	179	179	CD
cord-009615-xcz8m9a7	220	52	)	)	-RRB-
cord-009615-xcz8m9a7	220	53	.	.	.
cord-009615-xcz8m9a7	221	1	After	after	IN
cord-009615-xcz8m9a7	221	2	25	25	CD
cord-009615-xcz8m9a7	221	3	years	year	NNS
cord-009615-xcz8m9a7	221	4	of	of	IN
cord-009615-xcz8m9a7	221	5	intensive	intensive	JJ
cord-009615-xcz8m9a7	221	6	investigation	investigation	NN
cord-009615-xcz8m9a7	221	7	,	,	,
cord-009615-xcz8m9a7	221	8	there	there	EX
cord-009615-xcz8m9a7	221	9	is	be	VBZ
cord-009615-xcz8m9a7	221	10	still	still	RB
cord-009615-xcz8m9a7	221	11	no	no	DT
cord-009615-xcz8m9a7	221	12	definite	definite	JJ
cord-009615-xcz8m9a7	221	13	autoantigen	autoantigen	NN
cord-009615-xcz8m9a7	221	14	,	,	,
cord-009615-xcz8m9a7	221	15	no	no	DT
cord-009615-xcz8m9a7	221	16	breakthrough	breakthrough	NN
cord-009615-xcz8m9a7	221	17	in	in	IN
cord-009615-xcz8m9a7	221	18	laboratory	laboratory	NN
cord-009615-xcz8m9a7	221	19	diagnosis	diagnosis	NN
cord-009615-xcz8m9a7	221	20	,	,	,
cord-009615-xcz8m9a7	221	21	no	no	DT
cord-009615-xcz8m9a7	221	22	effective	effective	JJ
cord-009615-xcz8m9a7	221	23	long	long	JJ
cord-009615-xcz8m9a7	221	24	-	-	HYPH
cord-009615-xcz8m9a7	221	25	term	term	NN
cord-009615-xcz8m9a7	221	26	treatment	treatment	NN
cord-009615-xcz8m9a7	221	27	for	for	IN
cord-009615-xcz8m9a7	221	28	MS	MS	NNP
cord-009615-xcz8m9a7	221	29	(	(	-LRB-
cord-009615-xcz8m9a7	221	30	180	180	CD
cord-009615-xcz8m9a7	221	31	,	,	,
cord-009615-xcz8m9a7	221	32	181	181	CD
cord-009615-xcz8m9a7	221	33	)	)	-RRB-
cord-009615-xcz8m9a7	221	34	,	,	,
cord-009615-xcz8m9a7	221	35	and	and	CC
cord-009615-xcz8m9a7	221	36	there	there	EX
cord-009615-xcz8m9a7	221	37	are	be	VBP
cord-009615-xcz8m9a7	221	38	no	no	DT
cord-009615-xcz8m9a7	221	39	approaches	approach	NNS
cord-009615-xcz8m9a7	221	40	to	to	IN
cord-009615-xcz8m9a7	221	41	disease	disease	NN
cord-009615-xcz8m9a7	221	42	prevention	prevention	NN
cord-009615-xcz8m9a7	221	43	.	.	.
cord-009615-xcz8m9a7	222	1	A	a	DT
cord-009615-xcz8m9a7	222	2	fuller	full	JJR
cord-009615-xcz8m9a7	222	3	understanding	understanding	NN
cord-009615-xcz8m9a7	222	4	of	of	IN
cord-009615-xcz8m9a7	222	5	the	the	DT
cord-009615-xcz8m9a7	222	6	disease	disease	NN
cord-009615-xcz8m9a7	222	7	could	could	MD
cord-009615-xcz8m9a7	222	8	lead	lead	VB
cord-009615-xcz8m9a7	222	9	to	to	IN
cord-009615-xcz8m9a7	222	10	new	new	JJ
cord-009615-xcz8m9a7	222	11	diagnostic	diagnostic	JJ
cord-009615-xcz8m9a7	222	12	laboratory	laboratory	NN
cord-009615-xcz8m9a7	222	13	tests	test	NNS
cord-009615-xcz8m9a7	222	14	,	,	,
cord-009615-xcz8m9a7	222	15	and	and	CC
cord-009615-xcz8m9a7	222	16	to	to	IN
cord-009615-xcz8m9a7	222	17	new	new	JJ
cord-009615-xcz8m9a7	222	18	possibilities	possibility	NNS
cord-009615-xcz8m9a7	222	19	for	for	IN
cord-009615-xcz8m9a7	222	20	therapy	therapy	NN
cord-009615-xcz8m9a7	222	21	and	and	CC
cord-009615-xcz8m9a7	222	22	prevention	prevention	NN
cord-009615-xcz8m9a7	222	23	.	.	.
cord-009615-xcz8m9a7	223	1	The	the	DT
cord-009615-xcz8m9a7	223	2	direction	direction	NN
cord-009615-xcz8m9a7	223	3	of	of	IN
cord-009615-xcz8m9a7	223	4	MS	MS	NNP
cord-009615-xcz8m9a7	223	5	therapy	therapy	NN
cord-009615-xcz8m9a7	223	6	research	research	NN
cord-009615-xcz8m9a7	223	7	indicated	indicate	VBN
cord-009615-xcz8m9a7	223	8	by	by	IN
cord-009615-xcz8m9a7	223	9	a	a	DT
cord-009615-xcz8m9a7	223	10	latent	latent	NN
cord-009615-xcz8m9a7	223	11	-	-	HYPH
cord-009615-xcz8m9a7	223	12	virus	virus	NN
cord-009615-xcz8m9a7	223	13	paradigm	paradigm	NN
cord-009615-xcz8m9a7	223	14	would	would	MD
cord-009615-xcz8m9a7	223	15	be	be	VB
cord-009615-xcz8m9a7	223	16	a	a	DT
cord-009615-xcz8m9a7	223	17	combined	combined	JJ
cord-009615-xcz8m9a7	223	18	attack	attack	NN
cord-009615-xcz8m9a7	223	19	on	on	IN
cord-009615-xcz8m9a7	223	20	both	both	CC
cord-009615-xcz8m9a7	223	21	the	the	DT
cord-009615-xcz8m9a7	223	22	afferent	afferent	JJ
cord-009615-xcz8m9a7	223	23	and	and	CC
cord-009615-xcz8m9a7	223	24	efferent	efferent	JJ
cord-009615-xcz8m9a7	223	25	arms	arm	NNS
cord-009615-xcz8m9a7	223	26	of	of	IN
cord-009615-xcz8m9a7	223	27	the	the	DT
cord-009615-xcz8m9a7	223	28	immune	immune	JJ
cord-009615-xcz8m9a7	223	29	response	response	NN
cord-009615-xcz8m9a7	223	30	.	.	.
cord-009615-xcz8m9a7	224	1	This	this	DT
cord-009615-xcz8m9a7	224	2	would	would	MD
cord-009615-xcz8m9a7	224	3	involve	involve	VB
cord-009615-xcz8m9a7	224	4	inhibition	inhibition	NN
cord-009615-xcz8m9a7	224	5	of	of	IN
cord-009615-xcz8m9a7	224	6	viral	viral	JJ
cord-009615-xcz8m9a7	224	7	reactivation	reactivation	NN
cord-009615-xcz8m9a7	224	8	to	to	TO
cord-009615-xcz8m9a7	224	9	reduce	reduce	VB
cord-009615-xcz8m9a7	224	10	both	both	CC
cord-009615-xcz8m9a7	224	11	the	the	DT
cord-009615-xcz8m9a7	224	12	(	(	-LRB-
cord-009615-xcz8m9a7	224	13	peripheral	peripheral	JJ
cord-009615-xcz8m9a7	224	14	)	)	-RRB-
cord-009615-xcz8m9a7	224	15	immunogenic	immunogenic	JJ
cord-009615-xcz8m9a7	224	16	stimulus	stimulus	NN
cord-009615-xcz8m9a7	224	17	as	as	RB
cord-009615-xcz8m9a7	224	18	well	well	RB
cord-009615-xcz8m9a7	224	19	as	as	IN
cord-009615-xcz8m9a7	224	20	the	the	DT
cord-009615-xcz8m9a7	224	21	(	(	-LRB-
cord-009615-xcz8m9a7	224	22	central	central	JJ
cord-009615-xcz8m9a7	224	23	)	)	-RRB-
cord-009615-xcz8m9a7	224	24	antigenic	antigenic	JJ
cord-009615-xcz8m9a7	224	25	target	target	NN
cord-009615-xcz8m9a7	224	26	and	and	CC
cord-009615-xcz8m9a7	224	27	,	,	,
cord-009615-xcz8m9a7	224	28	if	if	IN
cord-009615-xcz8m9a7	224	29	possible	possible	JJ
cord-009615-xcz8m9a7	224	30	,	,	,
cord-009615-xcz8m9a7	224	31	selective	selective	JJ
cord-009615-xcz8m9a7	224	32	immunosuppression	immunosuppression	NN
cord-009615-xcz8m9a7	224	33	directed	direct	VBN
cord-009615-xcz8m9a7	224	34	toward	toward	IN
cord-009615-xcz8m9a7	224	35	a	a	DT
cord-009615-xcz8m9a7	224	36	CNS	CNS	NNP
cord-009615-xcz8m9a7	224	37	antiviral	antiviral	JJ
cord-009615-xcz8m9a7	224	38	immune	immune	JJ
cord-009615-xcz8m9a7	224	39	response	response	NN
cord-009615-xcz8m9a7	224	40	to	to	TO
cord-009615-xcz8m9a7	224	41	reduce	reduce	VB
cord-009615-xcz8m9a7	224	42	inflammation	inflammation	NN
cord-009615-xcz8m9a7	224	43	without	without	IN
cord-009615-xcz8m9a7	224	44	provoking	provoke	VBG
cord-009615-xcz8m9a7	224	45	increased	increase	VBN
cord-009615-xcz8m9a7	224	46	antigen	antigen	NN
cord-009615-xcz8m9a7	224	47	expression	expression	NN
cord-009615-xcz8m9a7	224	48	.	.	.
cord-009615-xcz8m9a7	225	1	Clearly	clearly	RB
cord-009615-xcz8m9a7	225	2	,	,	,
cord-009615-xcz8m9a7	225	3	a	a	DT
cord-009615-xcz8m9a7	225	4	solid	solid	JJ
cord-009615-xcz8m9a7	225	5	rationale	rationale	NN
cord-009615-xcz8m9a7	225	6	for	for	IN
cord-009615-xcz8m9a7	225	7	the	the	DT
cord-009615-xcz8m9a7	225	8	use	use	NN
cord-009615-xcz8m9a7	225	9	of	of	IN
cord-009615-xcz8m9a7	225	10	antiviral	antiviral	JJ
cord-009615-xcz8m9a7	225	11	agents	agent	NNS
cord-009615-xcz8m9a7	225	12	would	would	MD
cord-009615-xcz8m9a7	225	13	ensure	ensure	VB
cord-009615-xcz8m9a7	225	14	new	new	JJ
cord-009615-xcz8m9a7	225	15	emphasis	emphasis	NN
cord-009615-xcz8m9a7	225	16	on	on	IN
cord-009615-xcz8m9a7	225	17	their	-PRON-	PRP$
cord-009615-xcz8m9a7	225	18	development	development	NN
cord-009615-xcz8m9a7	225	19	and	and	CC
cord-009615-xcz8m9a7	225	20	future	future	JJ
cord-009615-xcz8m9a7	225	21	testing	testing	NN
cord-009615-xcz8m9a7	225	22	.	.	.
cord-009615-xcz8m9a7	226	1	A	a	DT
cord-009615-xcz8m9a7	226	2	final	final	JJ
cord-009615-xcz8m9a7	226	3	resolution	resolution	NN
cord-009615-xcz8m9a7	226	4	of	of	IN
cord-009615-xcz8m9a7	226	5	the	the	DT
cord-009615-xcz8m9a7	226	6	seemingly	seemingly	RB
cord-009615-xcz8m9a7	226	7	intractable	intractable	JJ
cord-009615-xcz8m9a7	226	8	MS	MS	NNP
cord-009615-xcz8m9a7	226	9	problem	problem	NN
cord-009615-xcz8m9a7	226	10	,	,	,
cord-009615-xcz8m9a7	226	11	which	which	WDT
cord-009615-xcz8m9a7	226	12	has	have	VBZ
cord-009615-xcz8m9a7	226	13	been	be	VBN
cord-009615-xcz8m9a7	226	14	aptly	aptly	RB
cord-009615-xcz8m9a7	226	15	described	describe	VBN
cord-009615-xcz8m9a7	226	16	[	[	-LRB-
cord-009615-xcz8m9a7	226	17	borrowing	borrowing	NN
cord-009615-xcz8m9a7	226	18	from	from	IN
cord-009615-xcz8m9a7	226	19	Churchill	Churchill	NNP
cord-009615-xcz8m9a7	226	20	)	)	-RRB-
cord-009615-xcz8m9a7	226	21	as	as	IN
cord-009615-xcz8m9a7	226	22	"	"	``
cord-009615-xcz8m9a7	226	23	a	a	DT
cord-009615-xcz8m9a7	226	24	riddIe	riddie	CD
cord-009615-xcz8m9a7	226	25	wrapped	wrap	VBN
cord-009615-xcz8m9a7	226	26	in	in	IN
cord-009615-xcz8m9a7	226	27	a	a	DT
cord-009615-xcz8m9a7	226	28	mystery	mystery	NN
cord-009615-xcz8m9a7	226	29	inside	inside	IN
cord-009615-xcz8m9a7	226	30	an	an	DT
cord-009615-xcz8m9a7	226	31	enigma	enigma	NN
cord-009615-xcz8m9a7	226	32	"	"	''
cord-009615-xcz8m9a7	226	33	(	(	-LRB-
cord-009615-xcz8m9a7	226	34	172	172	CD
cord-009615-xcz8m9a7	226	35	)	)	-RRB-
cord-009615-xcz8m9a7	226	36	,	,	,
cord-009615-xcz8m9a7	226	37	will	will	MD
cord-009615-xcz8m9a7	226	38	require	require	VB
cord-009615-xcz8m9a7	226	39	the	the	DT
cord-009615-xcz8m9a7	226	40	framework	framework	NN
cord-009615-xcz8m9a7	226	41	of	of	IN
cord-009615-xcz8m9a7	226	42	an	an	DT
cord-009615-xcz8m9a7	226	43	authentic	authentic	JJ
cord-009615-xcz8m9a7	226	44	paradigm	paradigm	NN
cord-009615-xcz8m9a7	226	45	.	.	.
cord-009615-xcz8m9a7	227	1	Although	although	IN
cord-009615-xcz8m9a7	227	2	MS	MS	NNP
cord-009615-xcz8m9a7	227	3	is	be	VBZ
cord-009615-xcz8m9a7	227	4	now	now	RB
cord-009615-xcz8m9a7	227	5	frequently	frequently	RB
cord-009615-xcz8m9a7	227	6	described	describe	VBN
cord-009615-xcz8m9a7	227	7	as	as	IN
cord-009615-xcz8m9a7	227	8	an	an	DT
cord-009615-xcz8m9a7	227	9	autoimmune	autoimmune	JJ
cord-009615-xcz8m9a7	227	10	disease	disease	NN
cord-009615-xcz8m9a7	227	11	(	(	-LRB-
cord-009615-xcz8m9a7	227	12	182	182	CD
cord-009615-xcz8m9a7	227	13	)	)	-RRB-
cord-009615-xcz8m9a7	227	14	,	,	,
cord-009615-xcz8m9a7	227	15	the	the	DT
cord-009615-xcz8m9a7	227	16	use	use	NN
cord-009615-xcz8m9a7	227	17	of	of	IN
cord-009615-xcz8m9a7	227	18	a	a	DT
cord-009615-xcz8m9a7	227	19	latent	latent	JJ
cord-009615-xcz8m9a7	227	20	-	-	HYPH
cord-009615-xcz8m9a7	227	21	virus	virus	NN
cord-009615-xcz8m9a7	227	22	paradigm	paradigm	NN
cord-009615-xcz8m9a7	227	23	might	may	MD
cord-009615-xcz8m9a7	227	24	accelerate	accelerate	VB
cord-009615-xcz8m9a7	227	25	progress	progress	NN
cord-009615-xcz8m9a7	227	26	by	by	IN
cord-009615-xcz8m9a7	227	27	emphasizing	emphasize	VBG
cord-009615-xcz8m9a7	227	28	avenues	avenue	NNS
cord-009615-xcz8m9a7	227	29	of	of	IN
cord-009615-xcz8m9a7	227	30	research	research	NN
cord-009615-xcz8m9a7	227	31	which	which	WDT
cord-009615-xcz8m9a7	227	32	the	the	DT
cord-009615-xcz8m9a7	227	33	more	more	RBR
cord-009615-xcz8m9a7	227	34	narrowly	narrowly	RB
cord-009615-xcz8m9a7	227	35	based	base	VBN
cord-009615-xcz8m9a7	227	36	EAE	EAE	NNP
cord-009615-xcz8m9a7	227	37	I	-PRON-	PRP
cord-009615-xcz8m9a7	227	38	autoimmunity	autoimmunity	IN
cord-009615-xcz8m9a7	227	39	paradigm	paradigm	NN
cord-009615-xcz8m9a7	227	40	bypasses	bypass	VBZ
cord-009615-xcz8m9a7	227	41	.	.	.
cord-009615-xcz8m9a7	227	42	 	 	_SP
cord-009615-xcz8m9a7	228	1	Encephalomyelitis	Encephalomyelitis	NNP
cord-009615-xcz8m9a7	228	2	accompanied	accompany	VBN
cord-009615-xcz8m9a7	228	3	by	by	IN
cord-009615-xcz8m9a7	228	4	myelin	myelin	JJ
cord-009615-xcz8m9a7	228	5	destruction	destruction	NN
cord-009615-xcz8m9a7	228	6	experimentally	experimentally	RB
cord-009615-xcz8m9a7	228	7	produced	produce	VBN
cord-009615-xcz8m9a7	228	8	in	in	IN
cord-009615-xcz8m9a7	228	9	monkeys	monkey	NNS
cord-009615-xcz8m9a7	228	10	JC	JC	NNP
cord-009615-xcz8m9a7	228	11	virus	virus	NN
cord-009615-xcz8m9a7	228	12	detection	detection	NN
cord-009615-xcz8m9a7	228	13	by	by	IN
cord-009615-xcz8m9a7	228	14	in	in	IN
cord-009615-xcz8m9a7	228	15	situ	situ	NN
cord-009615-xcz8m9a7	228	16	hybridization	hybridization	NN
cord-009615-xcz8m9a7	228	17	in	in	IN
cord-009615-xcz8m9a7	228	18	brain	brain	NN
cord-009615-xcz8m9a7	228	19	tissue	tissue	NN
cord-009615-xcz8m9a7	228	20	from	from	IN
cord-009615-xcz8m9a7	228	21	elderly	elderly	JJ
cord-009615-xcz8m9a7	228	22	patients	patient	NNS
cord-009615-xcz8m9a7	228	23	Distribution	Distribution	NNP
cord-009615-xcz8m9a7	228	24	of	of	IN
cord-009615-xcz8m9a7	228	25	papovavirus	papovavirus	NNP
cord-009615-xcz8m9a7	228	26	,	,	,
cord-009615-xcz8m9a7	228	27	myelin	myelin	NN
cord-009615-xcz8m9a7	228	28	-	-	HYPH
cord-009615-xcz8m9a7	228	29	associated	associate	VBN
cord-009615-xcz8m9a7	228	30	glycoprotein	glycoprotein	NN
cord-009615-xcz8m9a7	228	31	,	,	,
cord-009615-xcz8m9a7	228	32	and	and	CC
cord-009615-xcz8m9a7	228	33	myelin	myelin	JJ
cord-009615-xcz8m9a7	228	34	basic	basic	JJ
cord-009615-xcz8m9a7	228	35	protein	protein	NN
cord-009615-xcz8m9a7	228	36	in	in	IN
cord-009615-xcz8m9a7	228	37	progressive	progressive	JJ
cord-009615-xcz8m9a7	228	38	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	228	39	leukoencephalopathy	leukoencephalopathy	JJ
cord-009615-xcz8m9a7	228	40	lesions	lesion	NNS
cord-009615-xcz8m9a7	229	1	Progressive	progressive	JJ
cord-009615-xcz8m9a7	229	2	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	229	3	leukoencephalopathy	leukoencephalopathy	NNP
cord-009615-xcz8m9a7	229	4	Multiple	Multiple	NNP
cord-009615-xcz8m9a7	229	5	Sclerosis	Sclerosis	NNP
cord-009615-xcz8m9a7	229	6	:	:	:
cord-009615-xcz8m9a7	230	1	lmmunological	lmmunological	JJ
cord-009615-xcz8m9a7	230	2	,	,	,
cord-009615-xcz8m9a7	230	3	Diagnostic	Diagnostic	NNP
cord-009615-xcz8m9a7	230	4	,	,	,
cord-009615-xcz8m9a7	230	5	and	and	CC
cord-009615-xcz8m9a7	230	6	Therapeutic	Therapeutic	NNP
cord-009615-xcz8m9a7	230	7	Aspects	Aspects	NNPS
cord-009615-xcz8m9a7	230	8	Handbook	Handbook	NNP
cord-009615-xcz8m9a7	230	9	of	of	IN
cord-009615-xcz8m9a7	230	10	Multiple	Multiple	NNP
cord-009615-xcz8m9a7	230	11	Sclerosis	Sclerosis	NNP
cord-009615-xcz8m9a7	230	12	McAlpine	McAlpine	NNP
cord-009615-xcz8m9a7	230	13	's	's	POS
cord-009615-xcz8m9a7	230	14	Multiple	Multiple	NNP
cord-009615-xcz8m9a7	230	15	Sclerosis	Sclerosis	NNP
cord-009615-xcz8m9a7	230	16	Molecular	Molecular	NNP
cord-009615-xcz8m9a7	230	17	biology	biology	NN
cord-009615-xcz8m9a7	230	18	of	of	IN
cord-009615-xcz8m9a7	230	19	SV40	SV40	NNP
cord-009615-xcz8m9a7	230	20	and	and	CC
cord-009615-xcz8m9a7	230	21	the	the	DT
cord-009615-xcz8m9a7	230	22	human	human	JJ
cord-009615-xcz8m9a7	230	23	polyomaviruses	polyomaviruse	NNS
cord-009615-xcz8m9a7	230	24	BK	BK	NNP
cord-009615-xcz8m9a7	230	25	and	and	CC
cord-009615-xcz8m9a7	230	26	JC	JC	NNP
cord-009615-xcz8m9a7	230	27	Human	Human	NNP
cord-009615-xcz8m9a7	230	28	papovaviruses	papovavirus	NNS
cord-009615-xcz8m9a7	231	1	Studies	study	NNS
cord-009615-xcz8m9a7	231	2	of	of	IN
cord-009615-xcz8m9a7	231	3	JC	JC	NNP
cord-009615-xcz8m9a7	231	4	virus	virus	NN
cord-009615-xcz8m9a7	231	5	-	-	HYPH
cord-009615-xcz8m9a7	231	6	induced	induce	VBN
cord-009615-xcz8m9a7	231	7	nervous	nervous	JJ
cord-009615-xcz8m9a7	231	8	system	system	NN
cord-009615-xcz8m9a7	231	9	tumors	tumor	NNS
cord-009615-xcz8m9a7	231	10	in	in	IN
cord-009615-xcz8m9a7	231	11	the	the	DT
cord-009615-xcz8m9a7	231	12	Syrian	syrian	JJ
cord-009615-xcz8m9a7	231	13	hamster	hamster	NN
cord-009615-xcz8m9a7	231	14	Transformation	transformation	NN
cord-009615-xcz8m9a7	231	15	by	by	IN
cord-009615-xcz8m9a7	231	16	SV40	SV40	NNP
cord-009615-xcz8m9a7	231	17	and	and	CC
cord-009615-xcz8m9a7	231	18	polyoma	polyoma	NNP
cord-009615-xcz8m9a7	231	19	Common	Common	NNP
cord-009615-xcz8m9a7	231	20	Mechanisms	Mechanisms	NNPS
cord-009615-xcz8m9a7	231	21	of	of	IN
cord-009615-xcz8m9a7	231	22	Transformation	Transformation	NNP
cord-009615-xcz8m9a7	231	23	by	by	IN
cord-009615-xcz8m9a7	231	24	Small	small	JJ
cord-009615-xcz8m9a7	231	25	DNA	dna	NN
cord-009615-xcz8m9a7	231	26	Tumor	tumor	NN
cord-009615-xcz8m9a7	231	27	Viruses	virus	NNS
cord-009615-xcz8m9a7	232	1	Neuroimaging	neuroimage	VBG
cord-009615-xcz8m9a7	232	2	in	in	IN
cord-009615-xcz8m9a7	232	3	multiple	multiple	JJ
cord-009615-xcz8m9a7	232	4	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	232	5	Human	Human	NNP
cord-009615-xcz8m9a7	232	6	polyomavirus	polyomavirus	NNP
cord-009615-xcz8m9a7	232	7	in	in	IN
cord-009615-xcz8m9a7	232	8	pregnancy	pregnancy	NN
cord-009615-xcz8m9a7	232	9	.	.	.
cord-009615-xcz8m9a7	233	1	A	a	DT
cord-009615-xcz8m9a7	233	2	model	model	NN
cord-009615-xcz8m9a7	233	3	for	for	IN
cord-009615-xcz8m9a7	233	4	the	the	DT
cord-009615-xcz8m9a7	233	5	study	study	NN
cord-009615-xcz8m9a7	233	6	of	of	IN
cord-009615-xcz8m9a7	233	7	defence	defence	NN
cord-009615-xcz8m9a7	233	8	mechanisms	mechanism	NNS
cord-009615-xcz8m9a7	233	9	to	to	IN
cord-009615-xcz8m9a7	233	10	virus	virus	NN
cord-009615-xcz8m9a7	233	11	reactivation	reactivation	NN
cord-009615-xcz8m9a7	233	12	Occurrence	occurrence	NN
cord-009615-xcz8m9a7	233	13	and	and	CC
cord-009615-xcz8m9a7	233	14	significance	significance	NN
cord-009615-xcz8m9a7	233	15	of	of	IN
cord-009615-xcz8m9a7	233	16	papovaviruses	papovavirus	NNS
cord-009615-xcz8m9a7	233	17	BK	BK	NNP
cord-009615-xcz8m9a7	233	18	and	and	CC
cord-009615-xcz8m9a7	233	19	JC	JC	NNP
cord-009615-xcz8m9a7	233	20	in	in	IN
cord-009615-xcz8m9a7	233	21	the	the	DT
cord-009615-xcz8m9a7	233	22	urine	urine	NN
cord-009615-xcz8m9a7	233	23	Incidence	incidence	NN
cord-009615-xcz8m9a7	233	24	of	of	IN
cord-009615-xcz8m9a7	233	25	BK	BK	NNP
cord-009615-xcz8m9a7	233	26	virus	virus	NN
cord-009615-xcz8m9a7	233	27	and	and	CC
cord-009615-xcz8m9a7	233	28	JC	JC	NNP
cord-009615-xcz8m9a7	233	29	virus	virus	NN
cord-009615-xcz8m9a7	233	30	viruria	viruria	VBZ
cord-009615-xcz8m9a7	233	31	in	in	IN
cord-009615-xcz8m9a7	233	32	human	human	JJ
cord-009615-xcz8m9a7	233	33	immunodeficiency	immunodeficiency	NN
cord-009615-xcz8m9a7	233	34	virus	virus	NN
cord-009615-xcz8m9a7	233	35	-	-	HYPH
cord-009615-xcz8m9a7	233	36	infected	infect	VBN
cord-009615-xcz8m9a7	233	37	and	and	CC
cord-009615-xcz8m9a7	233	38	uninfected	uninfected	JJ
cord-009615-xcz8m9a7	233	39	subjects	subject	NNS
cord-009615-xcz8m9a7	233	40	Host	Host	NNP
cord-009615-xcz8m9a7	233	41	genes	gene	NNS
cord-009615-xcz8m9a7	233	42	that	that	WDT
cord-009615-xcz8m9a7	233	43	influence	influence	VBP
cord-009615-xcz8m9a7	233	44	susceptibility	susceptibility	NN
cord-009615-xcz8m9a7	233	45	to	to	IN
cord-009615-xcz8m9a7	233	46	viral	viral	JJ
cord-009615-xcz8m9a7	233	47	diseases	disease	NNS
cord-009615-xcz8m9a7	233	48	Genetics	genetic	NNS
cord-009615-xcz8m9a7	233	49	of	of	IN
cord-009615-xcz8m9a7	233	50	the	the	DT
cord-009615-xcz8m9a7	233	51	immune	immune	JJ
cord-009615-xcz8m9a7	233	52	response	response	NN
cord-009615-xcz8m9a7	233	53	to	to	IN
cord-009615-xcz8m9a7	233	54	infectious	infectious	JJ
cord-009615-xcz8m9a7	233	55	pathogens	pathogen	NNS
cord-009615-xcz8m9a7	233	56	11	11	CD
cord-009615-xcz8m9a7	233	57	989	989	CD
cord-009615-xcz8m9a7	233	58	)	)	-RRB-
cord-009615-xcz8m9a7	234	1	The	the	DT
cord-009615-xcz8m9a7	234	2	role	role	NN
cord-009615-xcz8m9a7	234	3	of	of	IN
cord-009615-xcz8m9a7	234	4	the	the	DT
cord-009615-xcz8m9a7	234	5	MHC	MHC	NNP
cord-009615-xcz8m9a7	234	6	and	and	CC
cord-009615-xcz8m9a7	234	7	T	T	NNP
cord-009615-xcz8m9a7	234	8	cell	cell	NN
cord-009615-xcz8m9a7	234	9	receptor	receptor	NN
cord-009615-xcz8m9a7	234	10	in	in	IN
cord-009615-xcz8m9a7	234	11	susceptibility	susceptibility	NN
cord-009615-xcz8m9a7	234	12	to	to	IN
cord-009615-xcz8m9a7	234	13	multiple	multiple	JJ
cord-009615-xcz8m9a7	234	14	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	234	15	Typing	typing	NN
cord-009615-xcz8m9a7	234	16	of	of	IN
cord-009615-xcz8m9a7	234	17	human	human	JJ
cord-009615-xcz8m9a7	234	18	polyomavirus	polyomavirus	JJ
cord-009615-xcz8m9a7	234	19	JC	JC	NNP
cord-009615-xcz8m9a7	234	20	virus	virus	NN
cord-009615-xcz8m9a7	234	21	on	on	IN
cord-009615-xcz8m9a7	234	22	the	the	DT
cord-009615-xcz8m9a7	234	23	basis	basis	NN
cord-009615-xcz8m9a7	234	24	of	of	IN
cord-009615-xcz8m9a7	234	25	restriction	restriction	NN
cord-009615-xcz8m9a7	234	26	fragment	fragment	NN
cord-009615-xcz8m9a7	234	27	length	length	NN
cord-009615-xcz8m9a7	235	1	polymorphisms	polymorphism	NNS
cord-009615-xcz8m9a7	235	2	Two	two	CD
cord-009615-xcz8m9a7	235	3	major	major	JJ
cord-009615-xcz8m9a7	235	4	types	type	NNS
cord-009615-xcz8m9a7	235	5	of	of	IN
cord-009615-xcz8m9a7	235	6	JC	JC	NNP
cord-009615-xcz8m9a7	235	7	virus	virus	NN
cord-009615-xcz8m9a7	235	8	defined	define	VBN
cord-009615-xcz8m9a7	235	9	in	in	IN
cord-009615-xcz8m9a7	235	10	PML	PML	NNP
cord-009615-xcz8m9a7	235	11	brain	brain	NN
cord-009615-xcz8m9a7	235	12	by	by	IN
cord-009615-xcz8m9a7	235	13	early	early	JJ
cord-009615-xcz8m9a7	235	14	and	and	CC
cord-009615-xcz8m9a7	235	15	late	late	JJ
cord-009615-xcz8m9a7	235	16	region	region	NN
cord-009615-xcz8m9a7	235	17	DNA	dna	NN
cord-009615-xcz8m9a7	235	18	coding	coding	NN
cord-009615-xcz8m9a7	235	19	sequence	sequence	NN
cord-009615-xcz8m9a7	235	20	Structure	structure	NN
cord-009615-xcz8m9a7	235	21	and	and	CC
cord-009615-xcz8m9a7	235	22	function	function	NN
cord-009615-xcz8m9a7	235	23	of	of	IN
cord-009615-xcz8m9a7	235	24	simian	simian	JJ
cord-009615-xcz8m9a7	235	25	virus	virus	NN
cord-009615-xcz8m9a7	235	26	40	40	CD
cord-009615-xcz8m9a7	235	27	large	large	JJ
cord-009615-xcz8m9a7	235	28	tumor	tumor	NN
cord-009615-xcz8m9a7	235	29	antigen	antigen	NN
cord-009615-xcz8m9a7	235	30	HLA	HLA	NNP
cord-009615-xcz8m9a7	235	31	-	-	HYPH
cord-009615-xcz8m9a7	235	32	DP	dp	NN
cord-009615-xcz8m9a7	235	33	beta	beta	NN
cord-009615-xcz8m9a7	235	34	and	and	CC
cord-009615-xcz8m9a7	235	35	susceptibility	susceptibility	NN
cord-009615-xcz8m9a7	235	36	to	to	IN
cord-009615-xcz8m9a7	235	37	multiple	multiple	JJ
cord-009615-xcz8m9a7	235	38	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	235	39	:	:	:
cord-009615-xcz8m9a7	235	40	An	an	DT
cord-009615-xcz8m9a7	235	41	analysis	analysis	NN
cord-009615-xcz8m9a7	235	42	of	of	IN
cord-009615-xcz8m9a7	235	43	Caucasoid	caucasoid	JJ
cord-009615-xcz8m9a7	235	44	and	and	CC
cord-009615-xcz8m9a7	235	45	Japanese	japanese	JJ
cord-009615-xcz8m9a7	235	46	patient	patient	NN
cord-009615-xcz8m9a7	235	47	populations	population	NNS
cord-009615-xcz8m9a7	235	48	Regulated	regulate	VBD
cord-009615-xcz8m9a7	235	49	replication	replication	NN
cord-009615-xcz8m9a7	235	50	of	of	IN
cord-009615-xcz8m9a7	235	51	an	an	DT
cord-009615-xcz8m9a7	235	52	episomal	episomal	JJ
cord-009615-xcz8m9a7	235	53	simian	simian	JJ
cord-009615-xcz8m9a7	235	54	virus	virus	NN
cord-009615-xcz8m9a7	235	55	40	40	CD
cord-009615-xcz8m9a7	235	56	origin	origin	NN
cord-009615-xcz8m9a7	235	57	plasmid	plasmid	NN
cord-009615-xcz8m9a7	235	58	in	in	IN
cord-009615-xcz8m9a7	235	59	COS7	COS7	NNP
cord-009615-xcz8m9a7	235	60	cells	cell	NNS
cord-009615-xcz8m9a7	235	61	Human	human	JJ
cord-009615-xcz8m9a7	235	62	polyomavirus	polyomavirus	JJ
cord-009615-xcz8m9a7	235	63	JC	JC	NNP
cord-009615-xcz8m9a7	235	64	virus	virus	NN
cord-009615-xcz8m9a7	235	65	genome	genome	NN
cord-009615-xcz8m9a7	235	66	Progressive	progressive	JJ
cord-009615-xcz8m9a7	235	67	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	235	68	leucoencephalopathy	leucoencephalopathy	NN
cord-009615-xcz8m9a7	235	69	:	:	:
cord-009615-xcz8m9a7	235	70	Detection	detection	NN
cord-009615-xcz8m9a7	235	71	of	of	IN
cord-009615-xcz8m9a7	235	72	papovavirus	papovavirus	NNP
cord-009615-xcz8m9a7	235	73	JC	JC	NNP
cord-009615-xcz8m9a7	235	74	in	in	IN
cord-009615-xcz8m9a7	235	75	kidney	kidney	NN
cord-009615-xcz8m9a7	235	76	tissue	tissue	NN
cord-009615-xcz8m9a7	235	77	Distribution	distribution	NN
cord-009615-xcz8m9a7	235	78	of	of	IN
cord-009615-xcz8m9a7	235	79	nonintegrated	nonintegrate	VBN
cord-009615-xcz8m9a7	235	80	DNA	DNA	NNP
cord-009615-xcz8m9a7	235	81	from	from	IN
cord-009615-xcz8m9a7	235	82	JC	JC	NNP
cord-009615-xcz8m9a7	235	83	papovavirus	papovavirus	NNP
cord-009615-xcz8m9a7	235	84	in	in	IN
cord-009615-xcz8m9a7	235	85	organs	organ	NNS
cord-009615-xcz8m9a7	235	86	of	of	IN
cord-009615-xcz8m9a7	235	87	patients	patient	NNS
cord-009615-xcz8m9a7	235	88	with	with	IN
cord-009615-xcz8m9a7	235	89	progressive	progressive	JJ
cord-009615-xcz8m9a7	235	90	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	235	91	leukoencephalopathy	leukoencephalopathy	NNP
cord-009615-xcz8m9a7	235	92	Involvement	Involvement	NNP
cord-009615-xcz8m9a7	235	93	of	of	IN
cord-009615-xcz8m9a7	235	94	JC	JC	NNP
cord-009615-xcz8m9a7	235	95	virus	virus	NN
cord-009615-xcz8m9a7	235	96	-	-	HYPH
cord-009615-xcz8m9a7	235	97	infected	infect	VBN
cord-009615-xcz8m9a7	235	98	mononudear	mononudear	JJ
cord-009615-xcz8m9a7	235	99	cells	cell	NNS
cord-009615-xcz8m9a7	235	100	from	from	IN
cord-009615-xcz8m9a7	235	101	the	the	DT
cord-009615-xcz8m9a7	235	102	bone	bone	NN
cord-009615-xcz8m9a7	235	103	marrow	marrow	NN
cord-009615-xcz8m9a7	235	104	and	and	CC
cord-009615-xcz8m9a7	235	105	spleen	spleen	NNS
cord-009615-xcz8m9a7	235	106	in	in	IN
cord-009615-xcz8m9a7	235	107	the	the	DT
cord-009615-xcz8m9a7	235	108	pathogenesis	pathogenesis	NN
cord-009615-xcz8m9a7	235	109	of	of	IN
cord-009615-xcz8m9a7	235	110	prcgressive	prcgressive	JJ
cord-009615-xcz8m9a7	235	111	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	235	112	leukoencephalopathy	leukoencephalopathy	NNP
cord-009615-xcz8m9a7	235	113	Cerebellar	Cerebellar	NNP
cord-009615-xcz8m9a7	235	114	progressive	progressive	JJ
cord-009615-xcz8m9a7	235	115	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	235	116	leukoencephalopathy	leukoencephalopathy	NNS
cord-009615-xcz8m9a7	235	117	:	:	:
cord-009615-xcz8m9a7	236	1	Localization	Localization	NNP
cord-009615-xcz8m9a7	236	2	of	of	IN
cord-009615-xcz8m9a7	236	3	JC	JC	NNP
cord-009615-xcz8m9a7	236	4	virus	virus	NN
cord-009615-xcz8m9a7	236	5	T	T	NNP
cord-009615-xcz8m9a7	236	6	-	-	HYPH
cord-009615-xcz8m9a7	236	7	antigen	antigen	NN
cord-009615-xcz8m9a7	236	8	in	in	IN
cord-009615-xcz8m9a7	236	9	granule	granule	NN
cord-009615-xcz8m9a7	236	10	cell	cell	NN
cord-009615-xcz8m9a7	236	11	neurons	neuron	NNS
cord-009615-xcz8m9a7	236	12	986	986	CD
cord-009615-xcz8m9a7	236	13	)	)	-RRB-
cord-009615-xcz8m9a7	237	1	JC	JC	NNP
cord-009615-xcz8m9a7	237	2	papovavirus	papovavirus	NNP
cord-009615-xcz8m9a7	237	3	large	large	JJ
cord-009615-xcz8m9a7	237	4	tumor	tumor	NN
cord-009615-xcz8m9a7	238	1	(	(	-LRB-
cord-009615-xcz8m9a7	238	2	T)-antigen	T)-antigen	NNP
cord-009615-xcz8m9a7	238	3	expression	expression	NN
cord-009615-xcz8m9a7	238	4	in	in	IN
cord-009615-xcz8m9a7	238	5	brain	brain	NN
cord-009615-xcz8m9a7	238	6	tissue	tissue	NN
cord-009615-xcz8m9a7	238	7	of	of	IN
cord-009615-xcz8m9a7	238	8	acquired	acquire	VBN
cord-009615-xcz8m9a7	238	9	immune	immune	JJ
cord-009615-xcz8m9a7	238	10	deficiency	deficiency	NN
cord-009615-xcz8m9a7	238	11	syndrome	syndrome	NN
cord-009615-xcz8m9a7	238	12	(	(	-LRB-
cord-009615-xcz8m9a7	238	13	AIDS	AIDS	NNP
cord-009615-xcz8m9a7	238	14	)	)	-RRB-
cord-009615-xcz8m9a7	238	15	and	and	CC
cord-009615-xcz8m9a7	238	16	non	non	JJ
cord-009615-xcz8m9a7	238	17	-	-	JJ
cord-009615-xcz8m9a7	238	18	AIDS	aids	JJ
cord-009615-xcz8m9a7	238	19	patients	patient	NNS
cord-009615-xcz8m9a7	238	20	with	with	IN
cord-009615-xcz8m9a7	238	21	progressive	progressive	JJ
cord-009615-xcz8m9a7	238	22	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	238	23	leukoencephalopathy	leukoencephalopathy	NNP
cord-009615-xcz8m9a7	238	24	Detection	detection	NN
cord-009615-xcz8m9a7	238	25	of	of	IN
cord-009615-xcz8m9a7	238	26	polyoma	polyoma	NNP
cord-009615-xcz8m9a7	238	27	virus	virus	NN
cord-009615-xcz8m9a7	238	28	DNA	dna	NN
cord-009615-xcz8m9a7	238	29	in	in	IN
cord-009615-xcz8m9a7	238	30	PML	PML	NNP
cord-009615-xcz8m9a7	238	31	-	-	HYPH
cord-009615-xcz8m9a7	238	32	brain	brain	NN
cord-009615-xcz8m9a7	238	33	tissue	tissue	NN
cord-009615-xcz8m9a7	238	34	by	by	IN
cord-009615-xcz8m9a7	238	35	(	(	-LRB-
cord-009615-xcz8m9a7	238	36	in	in	IN
cord-009615-xcz8m9a7	238	37	situ	situ	NN
cord-009615-xcz8m9a7	238	38	)	)	-RRB-
cord-009615-xcz8m9a7	239	1	hybridization	hybridization	NN
cord-009615-xcz8m9a7	239	2	Interaction	Interaction	NNP
cord-009615-xcz8m9a7	239	3	of	of	IN
cord-009615-xcz8m9a7	239	4	simian	simian	JJ
cord-009615-xcz8m9a7	239	5	virus	virus	NN
cord-009615-xcz8m9a7	239	6	40	40	CD
cord-009615-xcz8m9a7	239	7	and	and	CC
cord-009615-xcz8m9a7	239	8	human	human	JJ
cord-009615-xcz8m9a7	239	9	papovaviruses	papovavirus	NNS
cord-009615-xcz8m9a7	239	10	,	,	,
cord-009615-xcz8m9a7	239	11	BK	BK	NNP
cord-009615-xcz8m9a7	239	12	and	and	CC
cord-009615-xcz8m9a7	239	13	JC	JC	NNP
cord-009615-xcz8m9a7	240	1	,	,	,
cord-009615-xcz8m9a7	240	2	with	with	IN
cord-009615-xcz8m9a7	240	3	human	human	JJ
cord-009615-xcz8m9a7	240	4	vascular	vascular	JJ
cord-009615-xcz8m9a7	240	5	endothelial	endothelial	JJ
cord-009615-xcz8m9a7	240	6	cells	cell	NNS
cord-009615-xcz8m9a7	240	7	Brain	Brain	NNP
cord-009615-xcz8m9a7	240	8	vascular	vascular	JJ
cord-009615-xcz8m9a7	240	9	endothelial	endothelial	JJ
cord-009615-xcz8m9a7	240	10	cells	cell	NNS
cord-009615-xcz8m9a7	240	11	express	express	VBP
cord-009615-xcz8m9a7	240	12	JC	JC	NNP
cord-009615-xcz8m9a7	240	13	virus	virus	NN
cord-009615-xcz8m9a7	240	14	large	large	JJ
cord-009615-xcz8m9a7	240	15	tumor	tumor	NN
cord-009615-xcz8m9a7	240	16	antigen	antigen	NN
cord-009615-xcz8m9a7	240	17	in	in	IN
cord-009615-xcz8m9a7	240	18	immunocompetent	immunocompetent	JJ
cord-009615-xcz8m9a7	240	19	and	and	CC
cord-009615-xcz8m9a7	240	20	cyclophosphamide	cyclophosphamide	RB
cord-009615-xcz8m9a7	240	21	-	-	HYPH
cord-009615-xcz8m9a7	240	22	treated	treat	VBN
cord-009615-xcz8m9a7	240	23	hamsters	hamster	NNS
cord-009615-xcz8m9a7	240	24	Advances	advance	NNS
cord-009615-xcz8m9a7	240	25	in	in	IN
cord-009615-xcz8m9a7	240	26	cell	cell	NN
cord-009615-xcz8m9a7	240	27	biology	biology	NN
cord-009615-xcz8m9a7	240	28	of	of	IN
cord-009615-xcz8m9a7	240	29	bloodbrain	bloodbrain	NN
cord-009615-xcz8m9a7	240	30	barrier	barrier	NN
cord-009615-xcz8m9a7	240	31	transport	transport	NN
cord-009615-xcz8m9a7	240	32	Epitopes	Epitopes	NNP
cord-009615-xcz8m9a7	240	33	on	on	IN
cord-009615-xcz8m9a7	240	34	the	the	DT
cord-009615-xcz8m9a7	240	35	major	major	JJ
cord-009615-xcz8m9a7	240	36	capsid	capsid	NN
cord-009615-xcz8m9a7	240	37	protein	protein	NN
cord-009615-xcz8m9a7	240	38	of	of	IN
cord-009615-xcz8m9a7	240	39	simian	simian	JJ
cord-009615-xcz8m9a7	240	40	virus	virus	NN
cord-009615-xcz8m9a7	240	41	40	40	CD
cord-009615-xcz8m9a7	240	42	lmmunolabeling	lmmunolabele	VBG
cord-009615-xcz8m9a7	240	43	of	of	IN
cord-009615-xcz8m9a7	240	44	JC	JC	NNP
cord-009615-xcz8m9a7	240	45	virus	virus	NN
cord-009615-xcz8m9a7	240	46	large	large	JJ
cord-009615-xcz8m9a7	240	47	T	T	NNP
cord-009615-xcz8m9a7	240	48	antigen	antigen	NN
cord-009615-xcz8m9a7	240	49	in	in	IN
cord-009615-xcz8m9a7	240	50	neonatal	neonatal	JJ
cord-009615-xcz8m9a7	240	51	hamster	hamster	NN
cord-009615-xcz8m9a7	240	52	brain	brain	NN
cord-009615-xcz8m9a7	240	53	before	before	IN
cord-009615-xcz8m9a7	240	54	tumor	tumor	NN
cord-009615-xcz8m9a7	240	55	formation	formation	NN
cord-009615-xcz8m9a7	240	56	Cerebral	cerebral	JJ
cord-009615-xcz8m9a7	240	57	demyelination	demyelination	NN
cord-009615-xcz8m9a7	240	58	associated	associate	VBN
cord-009615-xcz8m9a7	240	59	with	with	IN
cord-009615-xcz8m9a7	240	60	polycythemia	polycythemia	NN
cord-009615-xcz8m9a7	240	61	Vera	Vera	NNP
cord-009615-xcz8m9a7	240	62	Association	Association	NNP
cord-009615-xcz8m9a7	240	63	of	of	IN
cord-009615-xcz8m9a7	240	64	papova	papova	NNP
cord-009615-xcz8m9a7	240	65	-	-	HYPH
cord-009615-xcz8m9a7	240	66	virions	virion	NNS
cord-009615-xcz8m9a7	240	67	with	with	IN
cord-009615-xcz8m9a7	240	68	a	a	DT
cord-009615-xcz8m9a7	240	69	human	human	JJ
cord-009615-xcz8m9a7	240	70	demyelinating	demyelinating	NN
cord-009615-xcz8m9a7	240	71	disease	disease	NN
cord-009615-xcz8m9a7	240	72	(	(	-LRB-
cord-009615-xcz8m9a7	240	73	progressive	progressive	JJ
cord-009615-xcz8m9a7	240	74	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	240	75	leukoencephalopathy	leukoencephalopathy	NNP
cord-009615-xcz8m9a7	240	76	)	)	-RRB-
cord-009615-xcz8m9a7	241	1	Wive1	wive1	JJ
cord-009615-xcz8m9a7	241	2	NA	NA	NNP
cord-009615-xcz8m9a7	241	3	(	(	-LRB-
cord-009615-xcz8m9a7	241	4	1	1	CD
cord-009615-xcz8m9a7	241	5	965	965	CD
cord-009615-xcz8m9a7	241	6	)	)	-RRB-
cord-009615-xcz8m9a7	242	1	Progressive	progressive	JJ
cord-009615-xcz8m9a7	242	2	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	242	3	leucoencephalopathy	leucoencephalopathy	NN
cord-009615-xcz8m9a7	242	4	Asymptomatic	asymptomatic	JJ
cord-009615-xcz8m9a7	242	5	progressive	progressive	JJ
cord-009615-xcz8m9a7	242	6	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	242	7	leukoencephalopathy	leukoencephalopathy	NNS
cord-009615-xcz8m9a7	242	8	(	(	-LRB-
cord-009615-xcz8m9a7	242	9	PML	PML	NNP
cord-009615-xcz8m9a7	242	10	)	)	-RRB-
cord-009615-xcz8m9a7	243	1	with	with	IN
cord-009615-xcz8m9a7	243	2	early	early	JJ
cord-009615-xcz8m9a7	243	3	lesions	lesion	NNS
cord-009615-xcz8m9a7	243	4	discovered	discover	VBN
cord-009615-xcz8m9a7	243	5	at	at	IN
cord-009615-xcz8m9a7	243	6	autopsy	autopsy	JJ
cord-009615-xcz8m9a7	243	7	Two	two	CD
cord-009615-xcz8m9a7	243	8	cases	case	NNS
cord-009615-xcz8m9a7	243	9	of	of	IN
cord-009615-xcz8m9a7	243	10	progressive	progressive	JJ
cord-009615-xcz8m9a7	243	11	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	243	12	leukcencephalopathy	leukcencephalopathy	NNP
cord-009615-xcz8m9a7	243	13	with	with	IN
cord-009615-xcz8m9a7	243	14	unusual	unusual	JJ
cord-009615-xcz8m9a7	243	15	aspects	aspect	NNS
cord-009615-xcz8m9a7	243	16	Virus	virus	NN
cord-009615-xcz8m9a7	243	17	-	-	HYPH
cord-009615-xcz8m9a7	243	18	cell	cell	NN
cord-009615-xcz8m9a7	243	19	interaction	interaction	NN
cord-009615-xcz8m9a7	243	20	in	in	IN
cord-009615-xcz8m9a7	243	21	oligodendroglia	oligodendroglia	NNP
cord-009615-xcz8m9a7	243	22	.	.	.
cord-009615-xcz8m9a7	244	1	astroglia	astroglia	NNP
cord-009615-xcz8m9a7	244	2	and	and	CC
cord-009615-xcz8m9a7	244	3	phagocyte	phagocyte	NNP
cord-009615-xcz8m9a7	244	4	in	in	IN
cord-009615-xcz8m9a7	244	5	progressive	progressive	JJ
cord-009615-xcz8m9a7	244	6	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	244	7	leukoencephalopathy	leukoencephalopathy	NNS
cord-009615-xcz8m9a7	244	8	.	.	.
cord-009615-xcz8m9a7	245	1	An	an	DT
cord-009615-xcz8m9a7	245	2	electron	electron	NN
cord-009615-xcz8m9a7	245	3	microscopic	microscopic	JJ
cord-009615-xcz8m9a7	245	4	study	study	NN
cord-009615-xcz8m9a7	245	5	Are	be	VBP
cord-009615-xcz8m9a7	245	6	astrocytes	astrocyte	NNS
cord-009615-xcz8m9a7	245	7	infected	infect	VBN
cord-009615-xcz8m9a7	245	8	in	in	IN
cord-009615-xcz8m9a7	245	9	progressive	progressive	JJ
cord-009615-xcz8m9a7	245	10	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	245	11	leukoencephalopathy	leukoencephalopathy	NNS
cord-009615-xcz8m9a7	245	12	(	(	-LRB-
cord-009615-xcz8m9a7	245	13	PML	PML	NNP
cord-009615-xcz8m9a7	245	14	)	)	-RRB-
cord-009615-xcz8m9a7	245	15	?	?	.
cord-009615-xcz8m9a7	246	1	968	968	CD
cord-009615-xcz8m9a7	246	2	)	)	-RRB-
cord-009615-xcz8m9a7	247	1	Pathogenesis	pathogenesis	NN
cord-009615-xcz8m9a7	247	2	of	of	IN
cord-009615-xcz8m9a7	247	3	viral	viral	JJ
cord-009615-xcz8m9a7	247	4	infections	infection	NNS
cord-009615-xcz8m9a7	247	5	of	of	IN
cord-009615-xcz8m9a7	247	6	the	the	DT
cord-009615-xcz8m9a7	247	7	nervous	nervous	JJ
cord-009615-xcz8m9a7	247	8	system	system	NN
cord-009615-xcz8m9a7	247	9	Serological	serological	JJ
cord-009615-xcz8m9a7	247	10	typing	typing	NN
cord-009615-xcz8m9a7	247	11	scheme	scheme	NN
cord-009615-xcz8m9a7	247	12	for	for	IN
cord-009615-xcz8m9a7	247	13	BK	BK	NNP
cord-009615-xcz8m9a7	247	14	-	-	HYPH
cord-009615-xcz8m9a7	247	15	like	like	JJ
cord-009615-xcz8m9a7	247	16	isolates	isolate	NNS
cord-009615-xcz8m9a7	247	17	of	of	IN
cord-009615-xcz8m9a7	247	18	human	human	JJ
cord-009615-xcz8m9a7	247	19	polyomavirus	polyomavirus	JJ
cord-009615-xcz8m9a7	247	20	White	White	NNP
cord-009615-xcz8m9a7	247	21	Ill	Ill	NNP
cord-009615-xcz8m9a7	247	22	FA	FA	NNP
cord-009615-xcz8m9a7	247	23	(	(	-LRB-
cord-009615-xcz8m9a7	247	24	1990	1990	CD
cord-009615-xcz8m9a7	247	25	)	)	-RRB-
cord-009615-xcz8m9a7	247	26	Antigenic	antigenic	JJ
cord-009615-xcz8m9a7	247	27	and	and	CC
cord-009615-xcz8m9a7	247	28	transforming	transform	VBG
cord-009615-xcz8m9a7	247	29	properties	property	NNS
cord-009615-xcz8m9a7	247	30	of	of	IN
cord-009615-xcz8m9a7	247	31	the	the	DT
cord-009615-xcz8m9a7	247	32	DB	DB	NNP
cord-009615-xcz8m9a7	247	33	strain	strain	NN
cord-009615-xcz8m9a7	247	34	of	of	IN
cord-009615-xcz8m9a7	247	35	the	the	DT
cord-009615-xcz8m9a7	247	36	human	human	JJ
cord-009615-xcz8m9a7	247	37	polyomavirus	polyomavirus	JJ
cord-009615-xcz8m9a7	247	38	BK	BK	NNP
cord-009615-xcz8m9a7	247	39	virus	virus	NN
cord-009615-xcz8m9a7	247	40	Nucleotide	nucleotide	JJ
cord-009615-xcz8m9a7	247	41	sequence	sequence	NN
cord-009615-xcz8m9a7	247	42	of	of	IN
cord-009615-xcz8m9a7	247	43	the	the	DT
cord-009615-xcz8m9a7	247	44	human	human	JJ
cord-009615-xcz8m9a7	247	45	polyomavirus	polyomavirus	NNP
cord-009615-xcz8m9a7	247	46	AS	as	IN
cord-009615-xcz8m9a7	247	47	virus	virus	NN
cord-009615-xcz8m9a7	247	48	,	,	,
cord-009615-xcz8m9a7	247	49	an	an	DT
cord-009615-xcz8m9a7	247	50	antigenic	antigenic	JJ
cord-009615-xcz8m9a7	247	51	variant	variant	NN
cord-009615-xcz8m9a7	247	52	of	of	IN
cord-009615-xcz8m9a7	247	53	BK	BK	NNP
cord-009615-xcz8m9a7	247	54	virus	virus	NN
cord-009615-xcz8m9a7	247	55	Prevalence	prevalence	NN
cord-009615-xcz8m9a7	247	56	of	of	IN
cord-009615-xcz8m9a7	247	57	the	the	DT
cord-009615-xcz8m9a7	247	58	archetypal	archetypal	JJ
cord-009615-xcz8m9a7	247	59	regulatory	regulatory	JJ
cord-009615-xcz8m9a7	247	60	region	region	NN
cord-009615-xcz8m9a7	247	61	and	and	CC
cord-009615-xcz8m9a7	247	62	sequence	sequence	NN
cord-009615-xcz8m9a7	247	63	polymorphisms	polymorphism	NNS
cord-009615-xcz8m9a7	247	64	in	in	IN
cord-009615-xcz8m9a7	247	65	non	non	JJ
cord-009615-xcz8m9a7	247	66	-	-	JJ
cord-009615-xcz8m9a7	247	67	passaged	passaged	JJ
cord-009615-xcz8m9a7	247	68	BK	BK	NNP
cord-009615-xcz8m9a7	247	69	virus	virus	NN
cord-009615-xcz8m9a7	247	70	variants	variant	VBZ
cord-009615-xcz8m9a7	247	71	980	980	CD
cord-009615-xcz8m9a7	247	72	)	)	-RRB-
cord-009615-xcz8m9a7	248	1	Progressive	progressive	JJ
cord-009615-xcz8m9a7	248	2	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	248	3	leukoencephalopathy	leukoencephalopathy	NN
cord-009615-xcz8m9a7	248	4	(	(	-LRB-
cord-009615-xcz8m9a7	248	5	PML	PML	NNP
cord-009615-xcz8m9a7	248	6	)	)	-RRB-
cord-009615-xcz8m9a7	248	7	:	:	:
cord-009615-xcz8m9a7	249	1	In	in	IN
cord-009615-xcz8m9a7	249	2	vitro	vitro	FW
cord-009615-xcz8m9a7	249	3	cell	cell	NN
cord-009615-xcz8m9a7	249	4	-	-	HYPH
cord-009615-xcz8m9a7	249	5	mediated	mediate	VBN
cord-009615-xcz8m9a7	249	6	immune	immune	JJ
cord-009615-xcz8m9a7	249	7	responses	response	NNS
cord-009615-xcz8m9a7	249	8	to	to	IN
cord-009615-xcz8m9a7	249	9	mitogens	mitogens	NNP
cord-009615-xcz8m9a7	249	10	and	and	CC
cord-009615-xcz8m9a7	249	11	JC	JC	NNP
cord-009615-xcz8m9a7	249	12	virus	virus	NN
cord-009615-xcz8m9a7	250	1	Cellmediated	cellmediate	VBN
cord-009615-xcz8m9a7	250	2	immune	immune	JJ
cord-009615-xcz8m9a7	250	3	responses	response	NNS
cord-009615-xcz8m9a7	250	4	to	to	IN
cord-009615-xcz8m9a7	250	5	BK	BK	NNP
cord-009615-xcz8m9a7	250	6	virus	virus	NN
cord-009615-xcz8m9a7	250	7	in	in	IN
cord-009615-xcz8m9a7	250	8	normal	normal	JJ
cord-009615-xcz8m9a7	250	9	individuals	individual	NNS
cord-009615-xcz8m9a7	251	1	Progressive	progressive	JJ
cord-009615-xcz8m9a7	251	2	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	251	3	leukoencephalopathy	leukoencephalopathy	NNP
cord-009615-xcz8m9a7	251	4	mimicking	mimic	VBG
cord-009615-xcz8m9a7	251	5	multiple	multiple	JJ
cord-009615-xcz8m9a7	251	6	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	251	7	as	as	IN
cord-009615-xcz8m9a7	251	8	only	only	JJ
cord-009615-xcz8m9a7	251	9	manifestation	manifestation	NN
cord-009615-xcz8m9a7	251	10	of	of	IN
cord-009615-xcz8m9a7	251	11	an	an	DT
cord-009615-xcz8m9a7	251	12	acquired	acquire	VBN
cord-009615-xcz8m9a7	251	13	immune	immune	JJ
cord-009615-xcz8m9a7	251	14	deficiency	deficiency	NN
cord-009615-xcz8m9a7	251	15	syndrome	syndrome	NN
cord-009615-xcz8m9a7	251	16	989	989	CD
cord-009615-xcz8m9a7	251	17	)	)	-RRB-
cord-009615-xcz8m9a7	252	1	Multiple	multiple	JJ
cord-009615-xcz8m9a7	252	2	sclerosislike	sclerosislike	NN
cord-009615-xcz8m9a7	252	3	illness	illness	NN
cord-009615-xcz8m9a7	252	4	occurring	occur	VBG
cord-009615-xcz8m9a7	252	5	with	with	IN
cord-009615-xcz8m9a7	252	6	human	human	JJ
cord-009615-xcz8m9a7	252	7	immunodeficiency	immunodeficiency	NN
cord-009615-xcz8m9a7	252	8	virus	virus	NN
cord-009615-xcz8m9a7	252	9	infection	infection	NN
cord-009615-xcz8m9a7	252	10	MS	MS	NNP
cord-009615-xcz8m9a7	252	11	-	-	HYPH
cord-009615-xcz8m9a7	252	12	like	like	JJ
cord-009615-xcz8m9a7	252	13	leukoencephalopathy	leukoencephalopathy	NNP
cord-009615-xcz8m9a7	252	14	in	in	IN
cord-009615-xcz8m9a7	252	15	HIV-1	HIV-1	NNP
cord-009615-xcz8m9a7	252	16	Fulminating	fulminate	VBG
cord-009615-xcz8m9a7	252	17	multiple	multiple	JJ
cord-009615-xcz8m9a7	252	18	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	252	19	-	-	HYPH
cord-009615-xcz8m9a7	252	20	like	like	JJ
cord-009615-xcz8m9a7	252	21	leukoencephalopathy	leukoencephalopathy	NNP
cord-009615-xcz8m9a7	252	22	revealing	reveal	VBG
cord-009615-xcz8m9a7	252	23	human	human	JJ
cord-009615-xcz8m9a7	252	24	immunodeficiency	immunodeficiency	NN
cord-009615-xcz8m9a7	252	25	virus	virus	NN
cord-009615-xcz8m9a7	252	26	infection	infection	NN
cord-009615-xcz8m9a7	252	27	992	992	CD
cord-009615-xcz8m9a7	252	28	)	)	-RRB-
cord-009615-xcz8m9a7	252	29	Relapsing	relapse	VBG
cord-009615-xcz8m9a7	252	30	and	and	CC
cord-009615-xcz8m9a7	252	31	remitting	remit	VBG
cord-009615-xcz8m9a7	252	32	human	human	JJ
cord-009615-xcz8m9a7	252	33	immunodeficiency	immunodeficiency	NN
cord-009615-xcz8m9a7	252	34	virus	virus	NN
cord-009615-xcz8m9a7	252	35	-	-	HYPH
cord-009615-xcz8m9a7	252	36	associated	associate	VBN
cord-009615-xcz8m9a7	252	37	leukoencephalomyelopathy	leukoencephalomyelopathy	NN
cord-009615-xcz8m9a7	253	1	Theiler	Theiler	NNP
cord-009615-xcz8m9a7	253	2	's	's	POS
cord-009615-xcz8m9a7	253	3	murine	murine	JJ
cord-009615-xcz8m9a7	253	4	encephalomyelitis	encephalomyelitis	NN
cord-009615-xcz8m9a7	253	5	virus	virus	NN
cord-009615-xcz8m9a7	253	6	(	(	-LRB-
cord-009615-xcz8m9a7	253	7	TMEV	TMEV	NNP
cord-009615-xcz8m9a7	253	8	)	)	-RRB-
cord-009615-xcz8m9a7	253	9	infection	infection	NN
cord-009615-xcz8m9a7	253	10	in	in	IN
cord-009615-xcz8m9a7	253	11	mice	mouse	NNS
cord-009615-xcz8m9a7	253	12	as	as	IN
cord-009615-xcz8m9a7	253	13	a	a	DT
cord-009615-xcz8m9a7	253	14	model	model	NN
cord-009615-xcz8m9a7	253	15	for	for	IN
cord-009615-xcz8m9a7	253	16	multiple	multiple	JJ
cord-009615-xcz8m9a7	253	17	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	254	1	The	the	DT
cord-009615-xcz8m9a7	254	2	early	early	JJ
cord-009615-xcz8m9a7	254	3	region	region	NN
cord-009615-xcz8m9a7	254	4	of	of	IN
cord-009615-xcz8m9a7	254	5	human	human	JJ
cord-009615-xcz8m9a7	254	6	papovavirus	papovavirus	NNP
cord-009615-xcz8m9a7	254	7	JC	JC	NNP
cord-009615-xcz8m9a7	254	8	induces	induce	VBZ
cord-009615-xcz8m9a7	254	9	dysmyelination	dysmyelination	NN
cord-009615-xcz8m9a7	254	10	in	in	IN
cord-009615-xcz8m9a7	254	11	transgenic	transgenic	JJ
cord-009615-xcz8m9a7	254	12	mice	mouse	NNS
cord-009615-xcz8m9a7	254	13	988	988	CD
cord-009615-xcz8m9a7	254	14	)	)	-RRB-
cord-009615-xcz8m9a7	255	1	Dysmyelination	dysmyelination	NN
cord-009615-xcz8m9a7	255	2	in	in	IN
cord-009615-xcz8m9a7	255	3	transgenic	transgenic	JJ
cord-009615-xcz8m9a7	255	4	mice	mouse	NNS
cord-009615-xcz8m9a7	255	5	containing	contain	VBG
cord-009615-xcz8m9a7	255	6	JC	JC	NNP
cord-009615-xcz8m9a7	255	7	virus	virus	NN
cord-009615-xcz8m9a7	255	8	early	early	JJ
cord-009615-xcz8m9a7	255	9	region	region	NN
cord-009615-xcz8m9a7	255	10	Transgenic	transgenic	JJ
cord-009615-xcz8m9a7	255	11	mice	mouse	NNS
cord-009615-xcz8m9a7	255	12	expressing	express	VBG
cord-009615-xcz8m9a7	255	13	polyoma	polyoma	NNP
cord-009615-xcz8m9a7	255	14	virus	virus	NN
cord-009615-xcz8m9a7	255	15	large	large	JJ
cord-009615-xcz8m9a7	255	16	T	T	NNP
cord-009615-xcz8m9a7	255	17	antigen	antigen	NN
cord-009615-xcz8m9a7	255	18	in	in	IN
cord-009615-xcz8m9a7	255	19	astrocytes	astrocyte	NNS
cord-009615-xcz8m9a7	255	20	develop	develop	VBP
cord-009615-xcz8m9a7	255	21	severe	severe	JJ
cord-009615-xcz8m9a7	255	22	dysmyelination	dysmyelination	NN
cord-009615-xcz8m9a7	255	23	of	of	IN
cord-009615-xcz8m9a7	255	24	the	the	DT
cord-009615-xcz8m9a7	255	25	central	central	JJ
cord-009615-xcz8m9a7	255	26	nervous	nervous	JJ
cord-009615-xcz8m9a7	255	27	system	system	NN
cord-009615-xcz8m9a7	255	28	Human	Human	NNP
cord-009615-xcz8m9a7	255	29	Polyomaviruses	Polyomaviruses	NNPS
cord-009615-xcz8m9a7	255	30	Prevalence	prevalence	NN
cord-009615-xcz8m9a7	255	31	of	of	IN
cord-009615-xcz8m9a7	255	32	antibodies	antibody	NNS
cord-009615-xcz8m9a7	255	33	to	to	IN
cord-009615-xcz8m9a7	255	34	a	a	DT
cord-009615-xcz8m9a7	255	35	human	human	JJ
cord-009615-xcz8m9a7	255	36	papova	papova	NN
cord-009615-xcz8m9a7	255	37	virus	virus	NN
cord-009615-xcz8m9a7	255	38	(	(	-LRB-
cord-009615-xcz8m9a7	255	39	BK	BK	NNP
cord-009615-xcz8m9a7	255	40	virus	virus	NN
cord-009615-xcz8m9a7	255	41	)	)	-RRB-
cord-009615-xcz8m9a7	255	42	in	in	IN
cord-009615-xcz8m9a7	255	43	subacute	subacute	JJ
cord-009615-xcz8m9a7	255	44	sclerosing	sclerosing	NN
cord-009615-xcz8m9a7	255	45	panencephalitis	panencephalitis	NN
cord-009615-xcz8m9a7	255	46	and	and	CC
cord-009615-xcz8m9a7	255	47	multiple	multiple	JJ
cord-009615-xcz8m9a7	255	48	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	255	49	patients	patient	NNS
cord-009615-xcz8m9a7	255	50	982	982	CD
cord-009615-xcz8m9a7	255	51	)	)	-RRB-
cord-009615-xcz8m9a7	255	52	Disease	Disease	NNP
cord-009615-xcz8m9a7	255	53	states	state	NNS
cord-009615-xcz8m9a7	255	54	involving	involve	VBG
cord-009615-xcz8m9a7	255	55	the	the	DT
cord-009615-xcz8m9a7	255	56	white	white	JJ
cord-009615-xcz8m9a7	255	57	matter	matter	NN
cord-009615-xcz8m9a7	255	58	of	of	IN
cord-009615-xcz8m9a7	255	59	the	the	DT
cord-009615-xcz8m9a7	255	60	central	central	JJ
cord-009615-xcz8m9a7	255	61	nervous	nervous	JJ
cord-009615-xcz8m9a7	255	62	system	system	NN
cord-009615-xcz8m9a7	255	63	.	.	.
cord-009615-xcz8m9a7	256	1	Part	part	NN
cord-009615-xcz8m9a7	256	2	I.	i.	NN
cord-009615-xcz8m9a7	257	1	The	the	DT
cord-009615-xcz8m9a7	257	2	primary	primary	JJ
cord-009615-xcz8m9a7	257	3	demyelinating	demyelinate	VBG
cord-009615-xcz8m9a7	257	4	diseases	disease	NNS
cord-009615-xcz8m9a7	258	1	The	the	DT
cord-009615-xcz8m9a7	258	2	topography	topography	NN
cord-009615-xcz8m9a7	258	3	of	of	IN
cord-009615-xcz8m9a7	258	4	plaques	plaque	NNS
cord-009615-xcz8m9a7	258	5	in	in	IN
cord-009615-xcz8m9a7	258	6	multiple	multiple	JJ
cord-009615-xcz8m9a7	258	7	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	258	8	Serial	serial	JJ
cord-009615-xcz8m9a7	258	9	gadolinium	gadolinium	NN
cord-009615-xcz8m9a7	258	10	-	-	HYPH
cord-009615-xcz8m9a7	258	11	enhanced	enhance	VBN
cord-009615-xcz8m9a7	258	12	magnetic	magnetic	JJ
cord-009615-xcz8m9a7	258	13	resonance	resonance	NN
cord-009615-xcz8m9a7	258	14	imaging	imaging	NN
cord-009615-xcz8m9a7	258	15	scans	scan	NNS
cord-009615-xcz8m9a7	258	16	in	in	IN
cord-009615-xcz8m9a7	258	17	patients	patient	NNS
cord-009615-xcz8m9a7	258	18	with	with	IN
cord-009615-xcz8m9a7	258	19	early	early	RB
cord-009615-xcz8m9a7	258	20	.	.	.
cord-009615-xcz8m9a7	259	1	relapsingremitting	relapsingremitte	VBG
cord-009615-xcz8m9a7	259	2	multiple	multiple	JJ
cord-009615-xcz8m9a7	259	3	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	259	4	:	:	:
cord-009615-xcz8m9a7	259	5	Implications	implication	NNS
cord-009615-xcz8m9a7	259	6	for	for	IN
cord-009615-xcz8m9a7	259	7	clinical	clinical	JJ
cord-009615-xcz8m9a7	259	8	trials	trial	NNS
cord-009615-xcz8m9a7	259	9	and	and	CC
cord-009615-xcz8m9a7	259	10	natural	natural	JJ
cord-009615-xcz8m9a7	259	11	history	history	NN
cord-009615-xcz8m9a7	260	1	Major	major	JJ
cord-009615-xcz8m9a7	260	2	differences	difference	NNS
cord-009615-xcz8m9a7	260	3	in	in	IN
cord-009615-xcz8m9a7	260	4	the	the	DT
cord-009615-xcz8m9a7	260	5	dynamics	dynamic	NNS
cord-009615-xcz8m9a7	260	6	of	of	IN
cord-009615-xcz8m9a7	260	7	primary	primary	JJ
cord-009615-xcz8m9a7	260	8	and	and	CC
cord-009615-xcz8m9a7	260	9	secondary	secondary	JJ
cord-009615-xcz8m9a7	260	10	progressive	progressive	JJ
cord-009615-xcz8m9a7	260	11	multiple	multiple	JJ
cord-009615-xcz8m9a7	260	12	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	260	13	Varakis	Varakis	NNP
cord-009615-xcz8m9a7	260	14	JN	JN	NNP
cord-009615-xcz8m9a7	260	15	(	(	-LRB-
cord-009615-xcz8m9a7	260	16	1979	1979	CD
cord-009615-xcz8m9a7	260	17	)	)	-RRB-
cord-009615-xcz8m9a7	261	1	Perinatal	perinatal	JJ
cord-009615-xcz8m9a7	261	2	induction	induction	NN
cord-009615-xcz8m9a7	261	3	of	of	IN
cord-009615-xcz8m9a7	261	4	medulloblastomas	medulloblastomas	NNP
cord-009615-xcz8m9a7	261	5	in	in	IN
cord-009615-xcz8m9a7	261	6	Syrian	syrian	JJ
cord-009615-xcz8m9a7	261	7	golden	golden	JJ
cord-009615-xcz8m9a7	261	8	hamsters	hamster	NNS
cord-009615-xcz8m9a7	261	9	by	by	IN
cord-009615-xcz8m9a7	261	10	a	a	DT
cord-009615-xcz8m9a7	261	11	human	human	JJ
cord-009615-xcz8m9a7	261	12	polyoma	polyoma	NN
cord-009615-xcz8m9a7	261	13	virus	virus	NN
cord-009615-xcz8m9a7	261	14	(	(	-LRB-
cord-009615-xcz8m9a7	261	15	JC	JC	NNP
cord-009615-xcz8m9a7	261	16	)	)	-RRB-
cord-009615-xcz8m9a7	262	1	Viral	viral	JJ
cord-009615-xcz8m9a7	262	2	neurooncogenesis	neurooncogenesis	NN
cord-009615-xcz8m9a7	262	3	Multiple	multiple	JJ
cord-009615-xcz8m9a7	262	4	cerebral	cerebral	JJ
cord-009615-xcz8m9a7	262	5	gliomas	glioma	NNS
cord-009615-xcz8m9a7	262	6	in	in	IN
cord-009615-xcz8m9a7	262	7	multiple	multiple	JJ
cord-009615-xcz8m9a7	262	8	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	262	9	Pathology	pathology	NN
cord-009615-xcz8m9a7	262	10	of	of	IN
cord-009615-xcz8m9a7	262	11	Tumors	tumor	NNS
cord-009615-xcz8m9a7	262	12	of	of	IN
cord-009615-xcz8m9a7	262	13	the	the	DT
cord-009615-xcz8m9a7	262	14	Nervous	Nervous	NNP
cord-009615-xcz8m9a7	262	15	System	System	NNP
cord-009615-xcz8m9a7	262	16	980	980	CD
cord-009615-xcz8m9a7	262	17	)	)	-RRB-
cord-009615-xcz8m9a7	263	1	Gliomatous	gliomatous	JJ
cord-009615-xcz8m9a7	263	2	transformation	transformation	NN
cord-009615-xcz8m9a7	263	3	and	and	CC
cord-009615-xcz8m9a7	263	4	demyelinating	demyelinate	VBG
cord-009615-xcz8m9a7	263	5	diseases	disease	NNS
cord-009615-xcz8m9a7	263	6	Cc	cc	NN
cord-009615-xcz8m9a7	263	7	-	-	HYPH
cord-009615-xcz8m9a7	263	8	occurrence	occurrence	NN
cord-009615-xcz8m9a7	263	9	of	of	IN
cord-009615-xcz8m9a7	263	10	multiple	multiple	JJ
cord-009615-xcz8m9a7	263	11	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	263	12	and	and	CC
cord-009615-xcz8m9a7	264	1	glioma	glioma	NN
cord-009615-xcz8m9a7	264	2	-Case	-Case	NNP
cord-009615-xcz8m9a7	264	3	report	report	NN
cord-009615-xcz8m9a7	264	4	and	and	CC
cord-009615-xcz8m9a7	264	5	neuropathologic	neuropathologic	JJ
cord-009615-xcz8m9a7	264	6	and	and	CC
cord-009615-xcz8m9a7	264	7	epidemiologic	epidemiologic	JJ
cord-009615-xcz8m9a7	264	8	review	review	NN
cord-009615-xcz8m9a7	265	1	Sclerose	Sclerose	NNP
cord-009615-xcz8m9a7	265	2	en	en	IN
cord-009615-xcz8m9a7	265	3	plaques	plaque	NNS
cord-009615-xcz8m9a7	265	4	et	et	IN
cord-009615-xcz8m9a7	265	5	gliome	gliome	NNP
cord-009615-xcz8m9a7	265	6	cerebral	cerebral	JJ
cord-009615-xcz8m9a7	265	7	Glioblastoma	Glioblastoma	NNP
cord-009615-xcz8m9a7	265	8	associated	associate	VBN
cord-009615-xcz8m9a7	265	9	with	with	IN
cord-009615-xcz8m9a7	265	10	multiple	multiple	JJ
cord-009615-xcz8m9a7	265	11	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	265	12	:	:	:
cord-009615-xcz8m9a7	265	13	Coincidence	coincidence	NN
cord-009615-xcz8m9a7	265	14	or	or	CC
cord-009615-xcz8m9a7	265	15	induction	induction	NN
cord-009615-xcz8m9a7	265	16	?	?	.
cord-009615-xcz8m9a7	266	1	974	974	LS
cord-009615-xcz8m9a7	266	2	)	)	-RRB-
cord-009615-xcz8m9a7	267	1	Leucoencephalopathie	Leucoencephalopathie	NNP
cord-009615-xcz8m9a7	267	2	multifocale	multifocale	NNP
cord-009615-xcz8m9a7	267	3	progressive	progressive	JJ
cord-009615-xcz8m9a7	267	4	et	et	NNP
cord-009615-xcz8m9a7	267	5	'	'	``
cord-009615-xcz8m9a7	267	6	gliomes	gliome	NNS
cord-009615-xcz8m9a7	267	7	'	'	POS
cord-009615-xcz8m9a7	267	8	multiples	multiple	NNS
cord-009615-xcz8m9a7	267	9	Multiple	multiple	JJ
cord-009615-xcz8m9a7	267	10	malignant	malignant	JJ
cord-009615-xcz8m9a7	267	11	astrocytomas	astrocytoma	NNS
cord-009615-xcz8m9a7	267	12	in	in	IN
cord-009615-xcz8m9a7	267	13	a	a	DT
cord-009615-xcz8m9a7	267	14	patient	patient	NN
cord-009615-xcz8m9a7	267	15	with	with	IN
cord-009615-xcz8m9a7	267	16	spontaneous	spontaneous	JJ
cord-009615-xcz8m9a7	267	17	progressive	progressive	JJ
cord-009615-xcz8m9a7	267	18	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	267	19	leukoencephalopathy	leukoencephalopathy	NNP
cord-009615-xcz8m9a7	267	20	Progressive	progressive	JJ
cord-009615-xcz8m9a7	267	21	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	267	22	leukoencephalopathy	leukoencephalopathy	NNS
cord-009615-xcz8m9a7	267	23	complicating	complicate	VBG
cord-009615-xcz8m9a7	267	24	systemic	systemic	JJ
cord-009615-xcz8m9a7	267	25	lupus	lupus	NN
cord-009615-xcz8m9a7	267	26	erythematosus	erythematosus	NN
cord-009615-xcz8m9a7	267	27	Progressive	progressive	JJ
cord-009615-xcz8m9a7	267	28	multifocal	multifocal	JJ
cord-009615-xcz8m9a7	267	29	leukoencephalopathy	leukoencephalopathy	NNS
cord-009615-xcz8m9a7	267	30	complicating	complicate	VBG
cord-009615-xcz8m9a7	267	31	systemic	systemic	JJ
cord-009615-xcz8m9a7	267	32	lupus	lupus	NN
cord-009615-xcz8m9a7	267	33	erythematosus	erythematosus	NN
cord-009615-xcz8m9a7	267	34	:	:	:
cord-009615-xcz8m9a7	268	1	Distribution	distribution	NN
cord-009615-xcz8m9a7	268	2	of	of	IN
cord-009615-xcz8m9a7	268	3	JC	JC	NNP
cord-009615-xcz8m9a7	268	4	virus	virus	NN
cord-009615-xcz8m9a7	268	5	in	in	IN
cord-009615-xcz8m9a7	268	6	chronically	chronically	RB
cord-009615-xcz8m9a7	268	7	demyelinated	demyelinate	VBN
cord-009615-xcz8m9a7	268	8	cerebellar	cerebellar	JJ
cord-009615-xcz8m9a7	268	9	lesions	lesion	NNS
cord-009615-xcz8m9a7	268	10	Poser	Poser	NNP
cord-009615-xcz8m9a7	268	11	CM	CM	NNP
cord-009615-xcz8m9a7	268	12	(	(	-LRB-
cord-009615-xcz8m9a7	268	13	1	1	CD
cord-009615-xcz8m9a7	268	14	992	992	CD
cord-009615-xcz8m9a7	268	15	)	)	-RRB-
cord-009615-xcz8m9a7	268	16	Multiple	multiple	JJ
cord-009615-xcz8m9a7	268	17	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	268	18	.	.	.
cord-009615-xcz8m9a7	269	1	Observations	observation	NNS
cord-009615-xcz8m9a7	269	2	and	and	CC
cord-009615-xcz8m9a7	269	3	reflections	reflection	NNS
cord-009615-xcz8m9a7	269	4	-	-	:
cord-009615-xcz8m9a7	269	5	A	a	DT
cord-009615-xcz8m9a7	269	6	personal	personal	JJ
cord-009615-xcz8m9a7	269	7	memoir	memoir	NN
cord-009615-xcz8m9a7	269	8	Cannella	Cannella	NNP
cord-009615-xcz8m9a7	269	9	6	6	CD
cord-009615-xcz8m9a7	269	10	,	,	,
cord-009615-xcz8m9a7	269	11	Brosnan	Brosnan	NNP
cord-009615-xcz8m9a7	269	12	CF	CF	NNP
cord-009615-xcz8m9a7	269	13	(	(	-LRB-
cord-009615-xcz8m9a7	269	14	1991	1991	CD
cord-009615-xcz8m9a7	269	15	)	)	-RRB-
cord-009615-xcz8m9a7	269	16	Identification	identification	NN
cord-009615-xcz8m9a7	269	17	of	of	IN
cord-009615-xcz8m9a7	269	18	lymphotoxin	lymphotoxin	NN
cord-009615-xcz8m9a7	269	19	and	and	CC
cord-009615-xcz8m9a7	269	20	tumor	tumor	NN
cord-009615-xcz8m9a7	269	21	necrosis	necrosis	NN
cord-009615-xcz8m9a7	269	22	factor	factor	NN
cord-009615-xcz8m9a7	269	23	in	in	IN
cord-009615-xcz8m9a7	269	24	multiple	multiple	JJ
cord-009615-xcz8m9a7	269	25	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	269	26	lesions	lesion	NNS
cord-009615-xcz8m9a7	269	27	Pathogenesis	Pathogenesis	NNP
cord-009615-xcz8m9a7	269	28	of	of	IN
cord-009615-xcz8m9a7	270	1	multiple	multiple	JJ
cord-009615-xcz8m9a7	270	2	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	270	3	Anti	anti	JJ
cord-009615-xcz8m9a7	270	4	-	-	JJ
cord-009615-xcz8m9a7	270	5	tumor	tumor	JJ
cord-009615-xcz8m9a7	270	6	necrosis	necrosis	NN
cord-009615-xcz8m9a7	270	7	factor	factor	NN
cord-009615-xcz8m9a7	270	8	therapy	therapy	NN
cord-009615-xcz8m9a7	270	9	abrogates	abrogate	VBZ
cord-009615-xcz8m9a7	270	10	autoimmune	autoimmune	JJ
cord-009615-xcz8m9a7	270	11	demyelination	demyelination	NN
cord-009615-xcz8m9a7	271	1	The	the	DT
cord-009615-xcz8m9a7	271	2	development	development	NN
cord-009615-xcz8m9a7	271	3	of	of	IN
cord-009615-xcz8m9a7	271	4	rational	rational	JJ
cord-009615-xcz8m9a7	271	5	strategies	strategy	NNS
cord-009615-xcz8m9a7	271	6	for	for	IN
cord-009615-xcz8m9a7	271	7	selective	selective	JJ
cord-009615-xcz8m9a7	271	8	immunotherapy	immunotherapy	NN
cord-009615-xcz8m9a7	271	9	against	against	IN
cord-009615-xcz8m9a7	271	10	autoimmune	autoimmune	JJ
cord-009615-xcz8m9a7	271	11	demyelinating	demyelinate	VBG
cord-009615-xcz8m9a7	271	12	disease	disease	NN
cord-009615-xcz8m9a7	271	13	T	T	NNP
cord-009615-xcz8m9a7	271	14	cell	cell	NN
cord-009615-xcz8m9a7	271	15	vaccination	vaccination	NN
cord-009615-xcz8m9a7	271	16	in	in	IN
cord-009615-xcz8m9a7	271	17	multiple	multiple	JJ
cord-009615-xcz8m9a7	271	18	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	271	19	:	:	:
cord-009615-xcz8m9a7	271	20	A	a	DT
cord-009615-xcz8m9a7	271	21	preliminary	preliminary	JJ
cord-009615-xcz8m9a7	271	22	report	report	NN
cord-009615-xcz8m9a7	271	23	Multiple	multiple	JJ
cord-009615-xcz8m9a7	271	24	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	271	25	:	:	:
cord-009615-xcz8m9a7	271	26	Additional	additional	JJ
cord-009615-xcz8m9a7	271	27	thoughts	thought	NNS
cord-009615-xcz8m9a7	271	28	Debate	debate	NN
cord-009615-xcz8m9a7	271	29	:	:	:
cord-009615-xcz8m9a7	271	30	Do	Do	NNP
cord-009615-xcz8m9a7	271	31	TCR	TCR	NNP
cord-009615-xcz8m9a7	271	32	genes	gene	NNS
cord-009615-xcz8m9a7	271	33	influence	influence	VBP
cord-009615-xcz8m9a7	271	34	susceptibility	susceptibility	NN
cord-009615-xcz8m9a7	271	35	to	to	IN
cord-009615-xcz8m9a7	271	36	autoimmune	autoimmune	JJ
cord-009615-xcz8m9a7	271	37	disease	disease	NN
cord-009615-xcz8m9a7	271	38	in	in	IN
cord-009615-xcz8m9a7	271	39	humans	human	NNS
cord-009615-xcz8m9a7	271	40	?	?	.
cord-009615-xcz8m9a7	272	1	Germline	Germline	NNP
cord-009615-xcz8m9a7	272	2	polymorphism	polymorphism	NN
cord-009615-xcz8m9a7	272	3	of	of	IN
cord-009615-xcz8m9a7	272	4	TCR	TCR	NNP
cord-009615-xcz8m9a7	272	5	genes	gene	NNS
cord-009615-xcz8m9a7	272	6	and	and	CC
cord-009615-xcz8m9a7	272	7	disease	disease	NN
cord-009615-xcz8m9a7	272	8	susceptibility	susceptibility	NN
cord-009615-xcz8m9a7	272	9	-Fact	-Fact	NNP
cord-009615-xcz8m9a7	272	10	or	or	CC
cord-009615-xcz8m9a7	272	11	hypothesis	hypothesis	NN
cord-009615-xcz8m9a7	272	12	Multiple	multiple	JJ
cord-009615-xcz8m9a7	272	13	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	272	14	:	:	:
cord-009615-xcz8m9a7	272	15	Therapeutic	therapeutic	JJ
cord-009615-xcz8m9a7	272	16	pessimism	pessimism	NN
cord-009615-xcz8m9a7	272	17	Natural	natural	JJ
cord-009615-xcz8m9a7	272	18	history	history	NN
cord-009615-xcz8m9a7	272	19	and	and	CC
cord-009615-xcz8m9a7	272	20	treatment	treatment	NN
cord-009615-xcz8m9a7	272	21	of	of	IN
cord-009615-xcz8m9a7	272	22	multiple	multiple	JJ
cord-009615-xcz8m9a7	272	23	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	272	24	Multiple	multiple	JJ
cord-009615-xcz8m9a7	272	25	sclerosis	sclerosis	NN
cord-009615-xcz8m9a7	272	26	:	:	:
cord-009615-xcz8m9a7	272	27	An	an	DT
cord-009615-xcz8m9a7	272	28	autoimmune	autoimmune	JJ
cord-009615-xcz8m9a7	272	29	disease	disease	NN
cord-009615-xcz8m9a7	272	30	of	of	IN
cord-009615-xcz8m9a7	272	31	multifactorial	multifactorial	JJ
cord-009615-xcz8m9a7	272	32	etiology	etiology	NN
cord-009615-xcz8m9a7	273	1	The	the	DT
cord-009615-xcz8m9a7	273	2	author	author	NN
cord-009615-xcz8m9a7	273	3	would	would	MD
cord-009615-xcz8m9a7	273	4	like	like	VB
cord-009615-xcz8m9a7	273	5	to	to	TO
cord-009615-xcz8m9a7	273	6	thank	thank	VB
cord-009615-xcz8m9a7	273	7	the	the	DT
cord-009615-xcz8m9a7	273	8	following	follow	VBG
cord-009615-xcz8m9a7	273	9	individuals	individual	NNS
cord-009615-xcz8m9a7	273	10	:	:	:
cord-009615-xcz8m9a7	273	11	Caroline	Caroline	NNP
cord-009615-xcz8m9a7	273	12	F.	F.	NNP
cord-009615-xcz8m9a7	273	13	Ryschkewitsch	Ryschkewitsch	NNP
cord-009615-xcz8m9a7	273	14	for	for	IN
cord-009615-xcz8m9a7	273	15	perfprming	perfprme	VBG
cord-009615-xcz8m9a7	273	16	the	the	DT
cord-009615-xcz8m9a7	273	17	immunocytochemical	immunocytochemical	JJ
cord-009615-xcz8m9a7	273	18	studies	study	NNS
cord-009615-xcz8m9a7	273	19	and	and	CC
cord-009615-xcz8m9a7	273	20	Karl	Karl	NNP
cord-009615-xcz8m9a7	273	21	Astrom	Astrom	NNP
cord-009615-xcz8m9a7	273	22	,	,	,
cord-009615-xcz8m9a7	273	23	Richard	Richard	NNP
cord-009615-xcz8m9a7	273	24	J.	J.	NNP
cord-009615-xcz8m9a7	273	25	Frisque	Frisque	NNP
cord-009615-xcz8m9a7	273	26	,	,	,
cord-009615-xcz8m9a7	273	27	Maria	Maria	NNP
cord-009615-xcz8m9a7	273	28	Mhzl6	Mhzl6	NNP
cord-009615-xcz8m9a7	273	29	,	,	,
cord-009615-xcz8m9a7	273	30	Holly	Holly	NNP
cord-009615-xcz8m9a7	273	31	G.	G.	NNP
cord-009615-xcz8m9a7	273	32	Ressetar	Ressetar	NNP
cord-009615-xcz8m9a7	273	33	and	and	CC
cord-009615-xcz8m9a7	273	34	Duard	Duard	NNP
cord-009615-xcz8m9a7	273	35	L.	L.	NNP
cord-009615-xcz8m9a7	273	36	Walker	Walker	NNP
cord-009615-xcz8m9a7	273	37	for	for	IN
cord-009615-xcz8m9a7	273	38	many	many	JJ
cord-009615-xcz8m9a7	273	39	helpful	helpful	JJ
cord-009615-xcz8m9a7	273	40	discussions	discussion	NNS
cord-009615-xcz8m9a7	273	41	,	,	,
cord-009615-xcz8m9a7	273	42	Linda	Linda	NNP
cord-009615-xcz8m9a7	273	43	Lowenstine	Lowenstine	NNP
cord-009615-xcz8m9a7	273	44	and	and	CC
cord-009615-xcz8m9a7	273	45	Andrew	Andrew	NNP
cord-009615-xcz8m9a7	273	46	Lackner	Lackner	NNP
cord-009615-xcz8m9a7	273	47	for	for	IN
cord-009615-xcz8m9a7	273	48	supplying	supply	VBG
cord-009615-xcz8m9a7	273	49	the	the	DT
cord-009615-xcz8m9a7	273	50	macaque	macaque	NN
cord-009615-xcz8m9a7	273	51	PML	PML	NNP
cord-009615-xcz8m9a7	273	52	brain	brain	NN
cord-009615-xcz8m9a7	273	53	tissue	tissue	NN
cord-009615-xcz8m9a7	273	54	,	,	,
cord-009615-xcz8m9a7	273	55	and	and	CC
cord-009615-xcz8m9a7	273	56	Walter	Walter	NNP
cord-009615-xcz8m9a7	273	57	Scott	Scott	NNP
cord-009615-xcz8m9a7	273	58	for	for	IN
cord-009615-xcz8m9a7	273	59	providing	provide	VBG
cord-009615-xcz8m9a7	273	60	the	the	DT
cord-009615-xcz8m9a7	273	61	monoclonal	monoclonal	JJ
cord-009615-xcz8m9a7	273	62	antibodies	antibody	NNS
cord-009615-xcz8m9a7	273	63	to	to	IN
cord-009615-xcz8m9a7	273	64	the	the	DT
cord-009615-xcz8m9a7	273	65	SV40	SV40	NNP
cord-009615-xcz8m9a7	273	66	capsid	capsid	NN
cord-009615-xcz8m9a7	273	67	protein	protein	NN
cord-009615-xcz8m9a7	273	68	.	.	.
cord-009615-xcz8m9a7	274	1	The	the	DT
cord-009615-xcz8m9a7	274	2	support	support	NN
cord-009615-xcz8m9a7	274	3	and	and	CC
cord-009615-xcz8m9a7	274	4	encouragement	encouragement	NN
cord-009615-xcz8m9a7	274	5	of	of	IN
cord-009615-xcz8m9a7	274	6	Henry	Henry	NNP
cord-009615-xcz8m9a7	274	7	deF.	deF.	NNP
cord-009615-xcz8m9a7	274	8	Webster	Webster	NNP
cord-009615-xcz8m9a7	274	9	is	be	VBZ
cord-009615-xcz8m9a7	274	10	also	also	RB
cord-009615-xcz8m9a7	274	11	gratefully	gratefully	RB
cord-009615-xcz8m9a7	274	12	acknowledged	acknowledge	VBN
cord-009615-xcz8m9a7	274	13	.	.	.