id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-343029-85ga6r7d	Haghpanah, Abdolreza	Potential mechanisms of SARS‐CoV‐2 action on male gonadal function and fertility: Current status and future prospects	2020-10-27		.txt	text/plain	4375	218	43	The aim of this review was to provide new insights into different possible mechanisms of involvement of male gonads with SARS‐CoV‐2 including investigating the ACE2 axis in testis, hormonal alterations in patients with COVID‐19, possible formation of anti‐sperm antibodies (ASA) and subsequently immunological infertility as a complication of SARS‐CoV‐2 infection. Considering the fact that the testis is highly enriched in ACE2 receptors and its vulnerability to SARS-CoV-2 invasion, detectable changes in semen analysis, alteration in sex hormones balance and, most importantly, anti-sperm antibodies (ASA) formation and sperm DNA fragmentation are considered to play a major role in male infertility. Search phrases used for different databases strategy included the following: "severe acute respiratory syndrome coronavirus 2", "2019 nCoV", "SARS-CoV-2", "coronavirus", "COVID-19", "reproductive system", "fertility", "infertility", "germ cells", "gamete", "spermatogonia", "spermatogenesis" "spermatozoa", "spermatozoan", "testis", "Sertoli cells", "Leydig cells", "Androgen", "steroidogenesis", "spermiogenesis", "spermiation", "development", "fertilization", "gonadal function", "sex hormones", "angiotensin-converting enzyme 2 receptor", "ACE2", "anti-sperm antibodies", "ASA", "sperm DNA fragmentation index", "DFI", and "semen analysis".	./cache/cord-343029-85ga6r7d.txt	./txt/cord-343029-85ga6r7d.txt