id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-342819-p8wp6yvo	De Groot, Anne S	Making vaccines “on demand”: A potential solution for emerging pathogens and biodefense?	2013-09-01		.txt	text/plain	5661	259	40	The accelerated process, as proposed by our group, would begin with analysis of the genomic sequence of an emerging pathogen with immunoinformatics tools, followed by rapid design of an epitope-based vaccine containing the most immunogenic components, using an integrated in silico approach illustrated in Figure 2 . Available evidence from animal studies suggests that the number of vaccine components (epitopes) required for full protection against disease is a small and definable subset that can be discovered using state-of-the-art computer programs such as the ones described and validated by EpiVax. 30, 31 We have proposed that any FastVax vaccine would include a minimum of 100 broadly reactive T cell epitopes in several strings, designed to induce multi-functional immune responses that are essential for protective immunity.	./cache/cord-342819-p8wp6yvo.txt	./txt/cord-342819-p8wp6yvo.txt