id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-315570-khm1veuv	González-Mora, Alejandro	Bacteriophage-Based Vaccines: A Potent Approach for Antigen Delivery	2020-09-04		.txt	text/plain	9969	455	40	This system relies on bacteriophages displaying proteins or peptides with high affinity to antigen-presenting cells or the antigen itself and at the same time they carry on their genome an eukaryotic expression cassette encoding a specific antigen with the final aim of increasing the immune response by combining both effects (Figure 1 ) [6] . developed a double-hybrid filamentous bacteriophage fd co-displaying peptides recognized by the Major Histocompatibility Complex (MHC) class I and MHC class II cell surface receptors and epitopes from the antigen MAGE aiming to enhance the anti-tumor immune activity based on CTL responses [62] . Thus, the adjuvant-like effect exhibited by phages in various vaccination studies along with their capacity to effectively present peptides or proteins to the immune system leading to the activation of cellular and humoral immune responses [40] demonstrates that engineered phage particles are a proper strategy to enhance the efficacy and safety of viral particle-based vaccines.	./cache/cord-315570-khm1veuv.txt	./txt/cord-315570-khm1veuv.txt