id author title date pages extension mime words sentences flesch summary cache txt cord-296356-qkvafy69 Garman, Elspeth SARS Proteomics Reveals Viral Secrets 2005-11-30 .txt text/plain 1306 74 51 The structure of the mutagenic base pair in the confines of a closed polymerase complex exposes some of those strategies. (2005) In a worldwide cooperative research effort involving a multidisciplinary approach, structural and functional characterization of the SARS virus and its host interactions has been swiftly pursued. By sequence alignment and structural comparison with all known H2A domains, as well as examination of functional data, the authors conjecture that proteins from this superfamily form an emerging group of nucleotide phosphatases, all with similar functionality. This has two pivotal consequences for understanding the biology of the virus: A systematic approach is essential, and, even more importantly, a deeper structural and functional knowledge of the many complexes that the SARS CoV proteins form with one another and with proteins of the host organisms will be required-research that is still in its infancy. ./cache/cord-296356-qkvafy69.txt ./txt/cord-296356-qkvafy69.txt