id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-277665-ac8txr3h	Grichko, Varvara P.	15 Nanodiamond Designing the Bio-Platform	2006-12-31		.txt	text/plain	8852	453	38	The chapter also summarizes different approaches to the surface functionalization of nanodiamonds (ND) particles—that is, the key in successful biomedical applications followed by a discussion of modification of diamond surfaces with nucleic acids and proteins. This chapter will be organized as follows: in the next section different approaches to the surface functionalization of ND particles, that is, the key in successful biomedical applications, will be summarized, followed by a discussion of modification of diamond surfaces with nucleic acids and proteins. Nanocrystalline diamond thin films covalently modified with DNA oligonucleotides following the photochemical modification of H-terminated surfaces with amine groups provide a very stable and highly selective platform for the surface hybridization reaction (Yang et al., 2002) . When made sufficiently electrically conducting by boron doping, thin-film and free-standing diamond electrodes exhibit remarkable chemical resistance to etching, a wide potential window, low background current responses, mechanical stability toward ultrasound-induced interfacial cavitation, a low stickiness in adsorption processes, and a high degree of tunability of the surface properties (reviewed by Compton et al., 2003) .	./cache/cord-277665-ac8txr3h.txt	./txt/cord-277665-ac8txr3h.txt