id author title date pages extension mime words sentences flesch summary cache txt cord-264814-v4wnmg03 Flanagan, Katie L. Progress and Pitfalls in the Quest for Effective SARS-CoV-2 (COVID-19) Vaccines 2020-10-02 .txt text/plain 15130 700 44 Herein, we review the current knowledge about the immune response to this novel virus as it pertains to the design of effective and safe SARS-CoV-2 vaccines and the range of novel and established approaches to vaccine development being taken. Herein, we review the current knowledge about the immune response to this novel virus as it pertains to the design of effective and safe SARS-CoV-2 vaccines and the range of novel and established approaches to vaccine development being taken. Comprehensive safety studies are particularly critical because some candidate vaccines use platform technologies that have not been examined extensively in human subjects to date, including some of the viral vectors, mRNA and nanoparticle constructs, and because of the potential for enhanced disease and adverse events related to aberrant immune responses to be seen upon infection pre-and post-licensure. ./cache/cord-264814-v4wnmg03.txt ./txt/cord-264814-v4wnmg03.txt