id author title date pages extension mime words sentences flesch summary cache txt cord-257318-jejgkcql Jain, K.K. Synthetic Biology and Personalized Medicine 2012-08-16 .txt text/plain 6096 285 33 Methods based on synthetic biology enable the design of novel strategies for the treatment of cancer, immune diseases metabolic disorders and infectious diseases as well as the production of cheap drugs [2] . Whereas genetic engineering focuses on individual genes, synthetic biology strings together a series of molecular components, such as DNA, RNA, proteins and cells, into circuits and networks. Synthetic gene network design and prototype therapeutic circuits will have an impact on future gene-and cell-based therapies and usher a new era of drug discovery that may enable treatment of complex diseases in a personalized manner. Among new technologies, synthetic biology will contribute by the introduction of therapeutic systems based on a synthetic genome, using an expanded genetic code, and designed for specific personalized drug synthesis as well as delivery and activation by a pathological signal. ./cache/cord-257318-jejgkcql.txt ./txt/cord-257318-jejgkcql.txt