id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-252838-av7ducrk	Lucchi, Naomi W.	Real-Time Fluorescence Loop Mediated Isothermal Amplification for the Diagnosis of Malaria	2010-10-29		.txt	text/plain	4913	250	52	In this study, we attempted to improve this method for malaria diagnosis by using a simple and portable device capable of performing both the amplification and detection (by fluorescence) of LAMP in one platform. reported a species specific LAMP diagnostic method; using clinical samples and a conventional DNA extraction method, they demonstrated sensitivity and specificity of 98.5% and 94.3% respectively compared to microscopy and a nested PCR [14] . We refer to this method as RealAmp. We demonstrate the utility of this method for the diagnosis of malaria by using published Plasmodium genus specific primers and comparing it to microscopy and a nested PCR method as described by Singh et al [18] . As summarized in Table 5 , results from the RealAmp method were comparable to the previously reported malaria LAMP assays [13] [14] [15] [16] [17] demonstrating reasonable sensitivity and specificity profiles when compared to microscopy and nested PCR.	./cache/cord-252838-av7ducrk.txt	./txt/cord-252838-av7ducrk.txt