id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-027309-8siz9rb8	Paul, Debjani	Developing a Point-of-Care Molecular Test to Detect SARS-CoV-2	2020-06-19		.txt	text/plain	2269	136	51	The recent pandemic of COVID-19 caused by the novel coronavirus (SARS-CoV-2) has drawn attention to the need for developing rapid and accurate diagnostic tests. The widespread use of these immunodiagnostic tests in clinical settings, in spite of their shortcomings, emphasizes the need for developing rapid and point-of-care (POC) tests that are based on molecular diagnostics (i.e., tests that detect the viral RNA directly in a manner similar to RT-PCR). We believe we can build on our past experience with isothermal DNA amplification techniques and paperfluidic devices to develop an isothermal amplification-based molecular diagnostic test for COVID-19 that can be deployed more easily. The ID NOW COVID-19 assay from Abbott, which recently got an emergency use authorization (EUA) from the US government for clinical use, detects SARS-CoV-2 RNA using an isothermal amplification test and can enable a clinical decision in as early as 13 min (ID NOWTM Covid-19 2020).	./cache/cord-027309-8siz9rb8.txt	./txt/cord-027309-8siz9rb8.txt