id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-017999-saxwqc2j	Travers, Andrew A.	Gene Regulation by HMGA and HMGB Chromosomal Proteins and Related Architectural DNA-Binding Proteins	2005		.txt	text/plain	6332	294	48	The eukaryotic abundant high mobility group HMGA and HMGB proteins can act as architectural transcription factors by promoting the assembly of higher-order protein-DNA complexes which can either activate or repress gene expression. Similarly rat SSRPl has been shown to facilitate the DNA binding of serum response factor and human SSRPl is associated with the y isoform of p63 in vivo at the endogenous MDM22inAp2nfl'"^^ promoters.^^ In most of these cases, the interaction of the HMG protein with the transcription factor has been detected in vitro and could, in principle, serve as the mechanism for recruitment of HMGB 1 or 2 to particular DNA sites.	./cache/cord-017999-saxwqc2j.txt	./txt/cord-017999-saxwqc2j.txt