id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-349451-vak2p7ac	Rocha, Francisco Airton Castro	Microbes, Helminths and Rheumatic Diseases	2020-05-07		.txt	text/plain	7465	355	33	Studies suggest the billions of germs that compose the gut microbiota influence one's innate and adaptive immune responses at the intestinal level, but these microorganisms may also impact rheumatic diseases. Evidence indicates that changes in the gut microbiome alter the pathogenesis of immune-mediated diseases such as rheumatoid arthritis and ankylosing spondylitis but also of other disorders like atherosclerosis and osteoarthritis. The pathogenesis of Chlamydia-related arthritis can be considered distinct from that associated with enteric bacteria since it involves metabolically active organisms residing long-term within monocytic cells in synovial tissues, after resolution of the primary genital infection and migration of the cells to the joint, a process that is known as persistence [56, [61] [62] [63] . Studies indicate inflammatory bowel disease, or, at least, intestinal inflammation, is more prevalent in SpA patients (AS or others) and some genes associated with AS are also associated with IBD [83, 85] , including genes related to gut physiology and immunology.	./cache/cord-349451-vak2p7ac.txt	./txt/cord-349451-vak2p7ac.txt