id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-348567-rvwxysvc	Panfili, F. M.	Possible role of vitamin D in Covid-19 infection in pediatric population	2020-06-15		.txt	text/plain	5375	229	36	CONCLUSIONS: In this review, we suggest that vitamin D supplementation might play a role in the prevention and/or treatment to SARS-CoV-2 infection disease, by modulating the immune response to the virus both in the adult and pediatric population. Although the effect of normal to high levels of vitamin D on increasing CD4+ count is still unclear, a recent review proved that vitamin D plays an important role in reducing the immune activation of HIV-infected patients. In this autoimmune disease using calcitriol supplementation reduces serum levels of antibodies and slows the progression of β cell destruction down in the early stages of the disease [38] , Interestingly, it has also been demonstrated that in Systemic Sclerosis (SSc) [39] the VDR could act as a negative regulator of TGF-β/ Hydroxyproline, col1a1, col3a1 and alfa-SMA mRNAs ↓ Prevention of bleomycin-induced lung fibrosis in a murine model [48] Smad signaling, thus making vitamin D a putative antifibrotic treatment in the early stages of the disease.	./cache/cord-348567-rvwxysvc.txt	./txt/cord-348567-rvwxysvc.txt