id author title date pages extension mime words sentences flesch summary cache txt cord-330830-x2swoy4d Kobayashi, Nobumichi Impact of Emerging, Re-Emerging and Zoonotic Viral Infectious Diseases, in a Virologist’s Perspective 2018-08-31 .txt text/plain 921 59 43 Factors related to humans and society are the most responsible for emergence and spread of infectious diseases. The number of infectious diseases outbreaks increased globally about 4 times from the 1980s to 2010, associated with an evident increase of zoonosis as well as vector-borne disease, compared with human-specific infections [4] . Increase of zoonosis and vector-borne diseases is related to global changes in environment and ecosystem which may be caused by climate change associated with global warming. Phylogenetic analysis combined with chronological tracing indicated that recent global spread of Chikungunya was caused synergistically by factors of humans, environment, vectors, and viruses [5] . A mutation in the envelope protein conferred increased viral growth in mosquito, which facilitated spread of this vector-born disease. Thus, spread of emerging viral diseases is considered to be caused by multifactorial mechanisms. The author declares no conflict of interest, financial or otherwise. Global rise in human infectious disease outbreaks ./cache/cord-330830-x2swoy4d.txt ./txt/cord-330830-x2swoy4d.txt