id author title date pages extension mime words sentences flesch summary cache txt cord-324875-04s0ysih Honigsbaum, Mark Introduction: microbes, networks, knowledge—disease ecology and emerging infectious diseases in time of COVID-19 2020-06-23 .txt text/plain 4043 148 40 More than twenty years ago, historian of science and medicine Andrew Mendelsohn asked, "Where did the modern, ecological understanding of epidemic disease come from?" Moving beyond Mendelsohn's answer, this collection of new essays considers the global history of disease ecology in the past century and shows how epidemics and pandemics have made "microbes complex". Adding to the complexities about the multiple intellectual origins of this nonreductionist perspective, terms such as "virulence," "pathogen," and "infection" have been historically defined in different ways in biology and medicine, creating semantic confusion about the nature of biological processes in host-parasite interactions (Méthot and Dentinger 2016) . In so doing, it could not help but provoke deep philosophical questions about what the French bacteriologist Charles Nicolle (1930) termed the "birth, life and death of infectious diseases" and the waxing and waning of epidemics in different historical epochs (see Méthot 2019a, this issue) , and what the Rockefeller researcher René Dubos called the "symbiosis between humankind and earth" (see Honigsbaum 2017a, b) . ./cache/cord-324875-04s0ysih.txt ./txt/cord-324875-04s0ysih.txt