id author title date pages extension mime words sentences flesch summary cache txt cord-321993-uazc3lyg Hedrick, Stephen M. The Imperative to Vaccinate 2018-10-31 .txt text/plain 4188 239 54 A simplified version is that diffuse or small host populations cannot sustain an acutely infectious agent, meaning one in which infection is followed by clearance and long-term immunity. So, in addition to the endless parade of cold viruses that circulate among us, we acquired a great many deadly infectious agents, such as those that cause diphtheria, influenza, measles, meningitis, mumps, plague, rubella, smallpox, typhus, whooping cough, and others. Smallpox eradication was our first and thus far only complete victory over a human disease-causing agent, made possible by universal, global vaccination, and intensive surveillance. Vaccination effectively reduces the number and density of the disease-susceptible people, making acutely infectious agents unsustainable in the population. The risk of disease for any individual is thus most importantly dependent on the collective immunity of the population, especially those most susceptible to infection, usually the youngest children and oldest adults. ./cache/cord-321993-uazc3lyg.txt ./txt/cord-321993-uazc3lyg.txt