id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-315131-4yb2b70g	Hammerschmidt, Sven	Threat of infection: Microbes of high pathogenic potential – strategies for detection, control and eradication	2005-06-28		.txt	text/plain	7177	343	40	This report highlights some of the lectures that were presented during the international symposium 'Threat of infection: Microbes of high potential -strategies for detection, control and eradication' in July 2004 in Wu¨rzburg (Germany). E. Kaufmann (Max-Planck-Institute for Infection Biology (MPI), Berlin) suggested that the following vaccination strategies against intracellular bacteria deserve consideration: (i) attenuated viable strains, (ii) naked DNA encoding protective antigens and (iii) protective antigens expressed by recombinant viable vectors (bacteria or viruses). Based on the initial finding that several live-attenuated PrV vaccine strains lack a major surface antigen (glycoprotein E, gE) which is invariably present in all field strains (Mettenleiter et al., 1985) , a simple ELISA system has been developed that is able to specifically detect the presence or absence of anti-gE antibodies in the animal (van Oirschot et al., 1986) .	./cache/cord-315131-4yb2b70g.txt	./txt/cord-315131-4yb2b70g.txt