id author title date pages extension mime words sentences flesch summary cache txt cord-312418-e4g5u1nz Melillo, Alessandro Rabbit Clinical Pathology 2007-09-18 .txt text/plain 6442 363 46 There is little information available that describes the effect of clinical disease on the blood parameters of companion rabbits, or on the use of blood tests as diagnostic and prognostic indicators. An intestinal isoenzyme is quite abundant, so serum ALP concentrations are actually the sum of these 3 isoenzymes, which may explain why many reference ranges are vague and wide and why raised ALP levels in clinically healthy animals are a common finding. Azotemia is also indicative of renal disease, usually affecting the rabbit patient in association with hyperkalemia or hypokalemia, hypercalcemia and coexisting hyperphosphatemia, nonregenerative anemia, and isostenuric urine. Blood urea levels below the reference range indicate hepatic insufficiency or muscle mass loss (e.g., dental disease). Hyperphosphatemia usually indicates chronic kidney failure (a loss of more than 80% of nephrons) given that serum phosphorus levels are normalized by compensatory mechanisms in early-onset renal disease. ./cache/cord-312418-e4g5u1nz.txt ./txt/cord-312418-e4g5u1nz.txt