id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-305299-vbhilmve	Santos, C. Sieiro	Determinants of COVID-19 disease severity in patients with underlying rheumatic disease	2020-07-27		.txt	text/plain	2941	149	39	CONCLUSIONS: Our results suggest that comorbidities, rheumatic disease activity and laboratorial abnormalities such as C-reactive protein (CRP), D-Dimer, lactate dehydrogenase (LDH), serum ferritin elevation significantly associated with mortality whereas previous use of rheumatic medication did not. It is not clear whether the use of immunosuppressive medication for rheumatic pathology may suppose a risk of developing SARS-CoV-2 infection, if rheumatic patients have a higher mortality rate than general population or what factors may be associated with COVID-19 severity [5] . Age, sex, comorbidities, rheumatic disease diagnosis, treatment for rheumatic disease and disease activity prior to infection, duration of hospital stay, symptoms before admission, radiographic abnormalities and laboratorial results at arrival were analysed. Our results suggest that comorbidities, rheumatic disease activity and laboratorial abnormalities such as C-reactive protein (CRP), D-Dimer, lactate dehydrogenase (LDH), ferritin serum elevation significantly associated with mortality whereas previous use of hydroxychloroquine, corticosteroid, dcDMARDS and biologic therapy did not.	./cache/cord-305299-vbhilmve.txt	./txt/cord-305299-vbhilmve.txt