id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-291687-kwu0otpi	Judson, Gregory L.	Cardiovascular Implications and Therapeutic Considerations in COVID-19 Infection	2020-06-13		.txt	text/plain	5569	273	40	A review of 44,672 confirmed COVID-19 cases from Wuhan, China, demonstrated increased mortality in patients with cardiovascular disease (10.5%), diabetes (7.3%), and hypertension (6%), which was significantly higher than the overall case-fatality rate of 2.3% [22] . These initial cases series have shown a similar relationship between underlying cardiac comorbidities with a higher prevalence of hypertension, diabetes, coronary artery disease, and obesity in patients requiring mechanical ventilation [24] . Early studies reported a prevalence of acute cardiac injury of 12% in the entire cohort as defined by either high sensitivity troponin (Hs Tn) or the MB fraction of creatinine kinase (CK-MB) [ 99 th percentile or new echocardiographic or electrocardiographic abnormalities with greater elevations in cardiac biomarkers among patients requiring ICU care [1, 20] . Case cohort studies included data in patients for whom the outcome and illness course helped further elucidate the role of cardiac injury in COVID-19 disease.	./cache/cord-291687-kwu0otpi.txt	./txt/cord-291687-kwu0otpi.txt