id author title date pages extension mime words sentences flesch summary cache txt cord-285613-hbd44euq Søborg, Christian Vaccines in a hurry 2009-05-26 .txt text/plain 3804 161 43 Early recognition of an emerging microbial threat Identification and characterization of the causative agent Rapid understanding of natural history, pathogenesis, molecular biology and epidemiology; building on work in related pathogens as well as ongoing clinical, laboratory and epidemiological studies Identification of potential vaccine candidates Identification of potential delivery systems and suitable adjuvant to improve immunogenicity and sparing of antigen and dosages Production at pilot plant level Development and acceptance of correlates of immunity Development and acceptance of correlates of safety Limited trials in animals and humans based on these correlates as outcome measures Fast-track approval of the vaccines Enhancing production capacity by public-private partnerships Based on risk assessment and defined objectives: implementation of emergency vaccination Post-licensure follow-up of emergency vaccination with data accessible in real-time to medicine-and public health agencies as a surrogate for phase III trials and ensuring development with advance purchase agreements to establish a market. ./cache/cord-285613-hbd44euq.txt ./txt/cord-285613-hbd44euq.txt