id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-274019-dao10kx9	Rife, Brittany D	Phylodynamic applications in 21(st) century global infectious disease research	2017-05-08		.txt	text/plain	6268	280	30	These innovative tools have greatly enhanced scientific investigations of the temporal and geographical origins, evolutionary history, and ecological risk factors associated with the growth and spread of viruses such as human immunodeficiency virus (HIV), Zika, and dengue and bacteria such as Methicillin-resistant Staphylococcus aureus. CONCLUSIONS: Capitalizing on an extensive review of the literature, we discuss the evolution of the field of infectious disease epidemiology and recent accomplishments, highlighting the advancements in phylodynamics, as well as the challenges and limitations currently facing researchers studying emerging pathogen epidemics across the globe. The reliance on phylodynamic methods for estimating a pathogen's population-level characteristics (e.g., effective population size) and their relationships with epidemiological data suffers from a high costincreasing the number of inference models, and thus parameters associated with these models, requires an even greater increase in the information content, or phylogenetic resolution, of the sequence alignment and associated phenotypic data.	./cache/cord-274019-dao10kx9.txt	./txt/cord-274019-dao10kx9.txt