id author title date pages extension mime words sentences flesch summary cache txt cord-273602-cq276tj8 Bavishi, Chirag Acute myocardial injury in patients hospitalized with COVID-19 infection: A review 2020-06-06 .txt text/plain 2116 123 39 Randomized trials are urgently needed to investigate treatment modalities to reduce the incidence and mortality associated with COVID-19 related acute myocardial injury. In this concise review, we will focus on acute myocardial injury in COVID-19 infection, its prevalence, plausible pathophysiologic mechanisms, guidance on the use of cardiac biomarkers, and general management strategies. In a prospective cohort study by Du et al(11) of 179 patients with COVID-19 pneumonia, troponin I ≥0.05 ng/mL was independently associated with mortality in addition to age ≥65 years, pre-existing cardiovascular (CV) or cerebrovascular diseases and CD3+CD8+ Tcells ≤75 cells/μL. Epidemiological studies and randomized trials are urgently needed to investigate treatment modalities regulating immune function and inhibiting inflammatory responses to reduce the incidence and mortality associated with COVID-19 related acute myocardial injury. Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality ./cache/cord-273602-cq276tj8.txt ./txt/cord-273602-cq276tj8.txt