id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-268561-vq1uhj5i	da Silva, Severino Jefferson Ribeiro	Clinical and Laboratory Diagnosis of SARS-CoV-2, the Virus Causing COVID-19	2020-08-04		.txt	text/plain	9916	594	47	11 The causative agent was identified as a novel CoV, eventually named SARS-CoV-2, and the respiratory syndrome associated with the infection was designated as coronavirus disease-2019 (COVID-19) by the World Health Organization (WHO). In direct tests, the clinical sample is examined directly for the presence of particles, virus antigens, or viral nucleic acids, whereas indirect methods detect the serological response against the infection (Figure 2 ). 11 Culture-based methods for SARS-CoV-2 detection have been used in research and public health laboratories in different parts of the world, but virus isolation is not recommended as a routine diagnostic procedure because it has low sensitivity, it is time-consuming, and it requires BSL-3 containment. 11 In addition to unequivocally confirming the diagnosis of a SARS-CoV-2 infection, regular sequencing of a percentage of patient samples from clinical cases can be used to monitor changes in the viral genome over time and trace transmission patterns.	./cache/cord-268561-vq1uhj5i.txt	./txt/cord-268561-vq1uhj5i.txt