id author title date pages extension mime words sentences flesch summary cache txt cord-264660-tfktgy57 Creech, C Buddy It’s True Even in a Pandemic: Children are Not Merely Little Adults 2020-05-30 .txt text/plain 980 64 55 In this issue of CID, Mehta et al (CID PAPER) provide a systematic review of pediatric COVID-19, evaluating the available literature to date to glean characteristics of disease and transmission. The authors report that children represent only 5% or less of diagnosed COVID cases and the data available at the time of review suggest that children are less likely to develop either severe pneumonia or the laboratory alterations commonly associated with severe disease, such as lymphopenia and elevated inflammatory markers. The authors also report that intrauterine transmission appears to be extremely uncommon and that newborns born to infected mothers are likely to experience either asymptomatic disease or mild disease. Taken together, it would appear that children experience a very different response to SARS-CoV-2 infection than adults and raises the hypothesis that dysregulated host responses may be the primary driver of disease severity. ./cache/cord-264660-tfktgy57.txt ./txt/cord-264660-tfktgy57.txt