id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-261301-8mw2kpmr	McVey, Scott	Vaccines in Veterinary Medicine: A Brief Review of History and Technology	2010-05-13		.txt	text/plain	4039	233	38	Nevertheless, both the effectiveness and imperfections of vaccination lead to the eventual global eradication of smallpox, and was the inspiration for development of the products and programs for immunization against several diseases in humans and animals. Table 1 describes the types of vaccines currently available to companion animal practitioners in most regions of the world 11-14 (http://www.aphis.usda.gov/animal_health/vet_biologics/ vb_licensed_products.shtml) These vaccines include very traditional inactivated antigen formulations, multiple attenuated agents, and new technologies such as poxvectored vaccines, defined subunit vaccines, and nucleic acid vaccines (see Table 1 ). Therefore, a well-differentiated antibody response with isotype switching, affinity maturation to high avidity, and memory requires some effective initial stimulation involving dendritic cells and expansion of regulatory T lymphocytes A claim that it is intended to prevent disease may be made only for products shown to be highly effective in preventing clinical disease in vaccinated and challenged animals.	./cache/cord-261301-8mw2kpmr.txt	./txt/cord-261301-8mw2kpmr.txt