id author title date pages extension mime words sentences flesch summary cache txt cord-261058-yu2qw02l Burgner, David Kawasaki disease: What is the epidemiology telling us about the etiology? 2005-06-03 .txt text/plain 5144 324 40 Thus in genetically susceptible children, acute infections such as those causing fever and rash, may result in unrecognised damage to the cardiovascular system that later manifests itself as adult cardiovascular disease. 3 The consensus view is that KD results from a widely distributed infectious agent (or possibly agents) that causes the clinical syndrome in genetically susceptible children. Kawasaki disease is more common in boys (male:female ratio 1.6:1) 1 a feature observed in many infectious diseases 30, 31 and also in coronary atherosclerosis, where sex differences in immune responses are suggested to mediate susceptibility. A recent report of an association between the presence of genetic material from a novel coronavirus and Kawasaki disease in a handful of cases 48 remains unproven and may reflect an epiphenomenon; the putative etiological agent is a relatively common viral pathogen in young children and it is unclear how long the DNA persists. ./cache/cord-261058-yu2qw02l.txt ./txt/cord-261058-yu2qw02l.txt