id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-253000-nwbmxepi	Margină, Denisa	Chronic Inflammation in the Context of Everyday Life: Dietary Changes as Mitigating Factors	2020-06-10		.txt	text/plain	8273	424	37	Fasting in combination with calorie restriction modulates molecular mechanisms such as m-TOR, FOXO, NRF2, AMPK, and sirtuins, ultimately leads to significantly reduced inflammatory marker levels, as well as improved metabolic markers. It has been found that intermittent fasting can prevent and reverse all aspects of metabolic syndrome in rodents: body fat, inflammation, and blood pressure are reduced; insulin sensitivity is increased; and the functional capacity of the neuromuscular and cardiovascular systems are improved [151] [152] [153] . In another study, which used the same fasting guidelines, improved metabolic markers were observed after periodic fasting, including a decrease in blood glucose levels associated with changes in gut microbiome composition [73] . These changes include increased fiber and polyphenol intake compared to the current western diets, but also well-structured, personalized fasting protocols, which can reduce the risk of metabolic disorders (Figure 3) .	./cache/cord-253000-nwbmxepi.txt	./txt/cord-253000-nwbmxepi.txt