id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-023584-yaxawqhj	Bucknall, R.A.	The Continuing Search for Antiviral Drugs	2008-04-10		.txt	text/plain	8497	339	48	Of course, if wide-spectrum leads appear, the choice of test virus may be irrelevant, but the antiviral compounds (as distinct from interferon inducers) known at present are characterized by their relatively limited spectrum of activity, e.g., methisazone is active only against poxviruses (Bauer and Sadler, 1960) and possibly adenoviruses (Bauer and Apostolov, 1966) ; l-aminoadamantane is active only against influenza A1 and As and not against other myxo-or paramyxoviruses (Davies et al., 1964) ; guanidine and a-hydroxybenzyl benzimidazole are active only against picornaviruses and not against other small ribonucleic acid (RNA) viruses (Eggers and Tamm, 1961) . In summary, a tissue culture screen should be able to proccss large numbers of tcst compounds, using viruses as relevant as possible to the diseases for which a drug is required, and should employ normal rather than neoplastic cells.	./cache/cord-023584-yaxawqhj.txt	./txt/cord-023584-yaxawqhj.txt