id author title date pages extension mime words sentences flesch summary cache txt cord-022505-17khcmta Delaney, Martha A. Rodentia 2018-10-26 .txt text/plain 10529 731 37 Common microscopic findings in rodents that may be misinterpreted as lesions include: multinucleated, karyomegalic, and cytomegalic hepatocytes are common in several rodent species and can increase with age ( Fig. 20 .1); hepatocellular intranuclear cytoplasmic invaginations (pseudoinclusions) (Fig. 20 .1); eosinophilic cytoplasmic spherical inclusions in renal tubular epithelial cells and hepatocytes seen predominantly male mice, rats, and hamsters; splenic extramedullary hematopoiesis, which is very common in healthy rodents of all ages (Fig. 20 .2); hemosiderin, lipofuscin, ceroid, and melanin (in dark or black coated animals) are commonly detected in various tissues, such as spleen, liver, kidney, and adrenal glands; cardiac muscle in the tunica of pulmonary veins in the lung is a normal finding in mice; male rodents may have refluxed seminal coagula in the urinary bladder and urethra that is thought to occur peri mortem; and adrenal X-zone vacuolation in female mice. ./cache/cord-022505-17khcmta.txt ./txt/cord-022505-17khcmta.txt