id author title date pages extension mime words sentences flesch summary cache txt cord-021825-4tkc61yq Hooks, John J. Infections Associated with Retinal Autoimmunity 2007-05-09 .txt text/plain 4977 276 48 We will highlight two human diseases triggered by Onchocerca volvulus or Toxoplasma gondii and an experimental model referred to as experimental coronavirus retinopathy (ECOR), triggered by the murine coronavims, mouse hepatitis virus (MHV). During the early phase of the disease (day 1-8) the virus infects and replicates within the retina of both BALB/c and CD-1 mouse stains [9] . Initial studies in the ECOR system, showed that inoculation of this JHM strain into the vitreous or anterior chamber of BALB/c mice resulted in retinal tissue damage [7, 8] . Analysis of pooled retinal mRNAs from untreated, mock-injected and virus infected BALB/ c mice revealed the presence of IL-6, IFN-y and TNF-~ mRNAs in virus infected retinas isolated during the acute disease, day 4 and day 8 PI. We therefore, evaluated the development of a retinal degenerative disease and the development of antiretinal autoantibodies in these two strains of mice after inoculation with JHM virus [11] . ./cache/cord-021825-4tkc61yq.txt ./txt/cord-021825-4tkc61yq.txt